CN110291438A - 用以在显微镜术中促进大区域成像的相机与试样对准 - Google Patents

用以在显微镜术中促进大区域成像的相机与试样对准 Download PDF

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Publication number
CN110291438A
CN110291438A CN201780086206.2A CN201780086206A CN110291438A CN 110291438 A CN110291438 A CN 110291438A CN 201780086206 A CN201780086206 A CN 201780086206A CN 110291438 A CN110291438 A CN 110291438A
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China
Prior art keywords
image sensor
sample
translation stage
pixels
pixel
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CN201780086206.2A
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English (en)
Chinese (zh)
Inventor
M·C·普特曼
J·B·普特曼
B·斯科特
D·法什博
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Photoelectron Image Ltd By Share Ltd
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Photoelectron Image Ltd By Share Ltd
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    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/24—Base structure
    • G02B21/26—Stages; Adjusting means therefor
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/362—Mechanical details, e.g. mountings for the camera or image sensor, housings
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/365—Control or image processing arrangements for digital or video microscopes
    • G02B21/367—Control or image processing arrangements for digital or video microscopes providing an output produced by processing a plurality of individual source images, e.g. image tiling, montage, composite images, depth sectioning, image comparison
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V10/00—Arrangements for image or video recognition or understanding
    • G06V10/10—Image acquisition
    • G06V10/16—Image acquisition using multiple overlapping images; Image stitching
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • G06V20/693—Acquisition
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N1/00—Scanning, transmission or reproduction of documents or the like, e.g. facsimile transmission; Details thereof
    • H04N1/387—Composing, repositioning or otherwise geometrically modifying originals
    • H04N1/3876—Recombination of partial images to recreate the original image

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  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Multimedia (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Theoretical Computer Science (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Signal Processing (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microscoopes, Condenser (AREA)
  • Length Measuring Devices By Optical Means (AREA)
CN201780086206.2A 2017-02-10 2017-05-16 用以在显微镜术中促进大区域成像的相机与试样对准 Pending CN110291438A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762457470P 2017-02-10 2017-02-10
US62/457,470 2017-02-10
PCT/US2017/032826 WO2018147888A1 (en) 2017-02-10 2017-05-16 Camera and specimen alignment to facilitate large area imaging in microscopy

Publications (1)

Publication Number Publication Date
CN110291438A true CN110291438A (zh) 2019-09-27

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CN201780086206.2A Pending CN110291438A (zh) 2017-02-10 2017-05-16 用以在显微镜术中促进大区域成像的相机与试样对准

Country Status (7)

Country Link
US (4) US10048477B1 (enExample)
EP (1) EP3580599B1 (enExample)
JP (2) JP7029821B2 (enExample)
KR (2) KR102414312B1 (enExample)
CN (1) CN110291438A (enExample)
TW (3) TWI764786B (enExample)
WO (1) WO2018147888A1 (enExample)

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CN110996002A (zh) * 2019-12-16 2020-04-10 深圳大学 显微镜聚焦方法、装置、计算机设备和存储介质
CN112469984A (zh) * 2019-12-31 2021-03-09 深圳迈瑞生物医疗电子股份有限公司 一种图像分析装置及其成像方法
CN115020270A (zh) * 2021-07-06 2022-09-06 深圳市森美协尔科技有限公司 晶圆测试设备及测试方法
CN119846827A (zh) * 2025-03-21 2025-04-18 浙江荷湖科技有限公司 一种针对电缸驱动的超大视野显微镜的视野调平方法

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KR102414312B1 (ko) 2017-02-10 2022-06-28 나노트로닉스 이미징, 인코포레이티드 현미경 검사에서 대 영역 이미징을 용이하게 하는 카메라 및 표본 정렬
US10545096B1 (en) * 2018-10-11 2020-01-28 Nanotronics Imaging, Inc. Marco inspection systems, apparatus and methods
US10481379B1 (en) 2018-10-19 2019-11-19 Nanotronics Imaging, Inc. Method and system for automatically mapping fluid objects on a substrate
US11294162B2 (en) 2019-02-07 2022-04-05 Nanotronics Imaging, Inc. Fluorescence microscopy inspection systems, apparatus and methods with darkfield channel
CN109752832B (zh) * 2019-03-25 2024-10-22 南京泰立瑞信息科技有限公司 一种显微镜镜筒在z轴上的运动控制方法及自动显微镜
US11593919B2 (en) 2019-08-07 2023-02-28 Nanotronics Imaging, Inc. System, method and apparatus for macroscopic inspection of reflective specimens
US10915992B1 (en) 2019-08-07 2021-02-09 Nanotronics Imaging, Inc. System, method and apparatus for macroscopic inspection of reflective specimens
DE102020113454A1 (de) 2020-05-19 2021-11-25 Carl Zeiss Microscopy Gmbh Mikroskop und Verfahren zum Erzeugen eines aus mehreren mikroskopischen Einzelbildern zusammengesetzten Bildes
US11748871B2 (en) * 2020-09-28 2023-09-05 KLA Corp. Alignment of a specimen for inspection and other processes
DE102021101439A1 (de) * 2021-01-22 2022-07-28 Carl Zeiss Microscopy Gmbh Mikroskopiesystem und verfahren zur rotationsüberprüfung einer mikroskopkamera
EP4063709A1 (en) * 2021-03-22 2022-09-28 Roche Diagnostics GmbH Laboratory system and corresponding method of operation
EP4177662A1 (en) * 2021-11-09 2023-05-10 Roche Diagnostics GmbH Instrument for automatically dissecting a biological specimen on a slide
CN116263539A (zh) * 2022-08-11 2023-06-16 上海睿钰生物科技有限公司 一种显微成像系统
DE102023114945B3 (de) 2023-06-07 2024-11-21 Carl Zeiss Meditec Ag Computerimplementiertes Bildgebungsverfahren und optisches Beobachtungsgerät
KR102852898B1 (ko) * 2023-12-15 2025-09-02 (주)코셈 다중창 박막을 이용한 대기압 전자현미경

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110996002A (zh) * 2019-12-16 2020-04-10 深圳大学 显微镜聚焦方法、装置、计算机设备和存储介质
CN110996002B (zh) * 2019-12-16 2021-08-24 深圳市瑞图生物技术有限公司 显微镜聚焦方法、装置、计算机设备和存储介质
CN112469984A (zh) * 2019-12-31 2021-03-09 深圳迈瑞生物医疗电子股份有限公司 一种图像分析装置及其成像方法
CN112469984B (zh) * 2019-12-31 2024-04-09 深圳迈瑞生物医疗电子股份有限公司 一种图像分析装置及其成像方法
CN115020270A (zh) * 2021-07-06 2022-09-06 深圳市森美协尔科技有限公司 晶圆测试设备及测试方法
CN119846827A (zh) * 2025-03-21 2025-04-18 浙江荷湖科技有限公司 一种针对电缸驱动的超大视野显微镜的视野调平方法
CN119846827B (zh) * 2025-03-21 2025-06-13 浙江荷湖科技有限公司 一种针对电缸驱动的超大视野显微镜的视野调平方法

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TW202234120A (zh) 2022-09-01
US20180231752A1 (en) 2018-08-16
TW201831858A (zh) 2018-09-01
US20180307016A1 (en) 2018-10-25
JP2022062236A (ja) 2022-04-19
EP3580599B1 (en) 2024-12-25
US10698191B2 (en) 2020-06-30
WO2018147888A1 (en) 2018-08-16
TW202140991A (zh) 2021-11-01
TWI764786B (zh) 2022-05-11
TWI734891B (zh) 2021-08-01
JP7428406B2 (ja) 2024-02-06
US20180335614A1 (en) 2018-11-22
KR20220093274A (ko) 2022-07-05
KR102414312B1 (ko) 2022-06-28
EP3580599A1 (en) 2019-12-18
KR102668955B1 (ko) 2024-05-23
US10416426B2 (en) 2019-09-17
JP2020507813A (ja) 2020-03-12
JP7029821B2 (ja) 2022-03-04
US20200326519A1 (en) 2020-10-15
US10048477B1 (en) 2018-08-14
KR20190112108A (ko) 2019-10-02
TWI849418B (zh) 2024-07-21
US11099368B2 (en) 2021-08-24

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