CN110279792B - Traditional Chinese medicine composition for preventing and treating ichthyophthiriasis of fishes and preparation method thereof - Google Patents
Traditional Chinese medicine composition for preventing and treating ichthyophthiriasis of fishes and preparation method thereof Download PDFInfo
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- CN110279792B CN110279792B CN201910589489.3A CN201910589489A CN110279792B CN 110279792 B CN110279792 B CN 110279792B CN 201910589489 A CN201910589489 A CN 201910589489A CN 110279792 B CN110279792 B CN 110279792B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/68—Plantaginaceae (Plantain Family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8962—Allium, e.g. garden onion, leek, garlic or chives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
Abstract
The invention discloses a traditional Chinese medicine composition for preventing and treating ichthyophthiriasis of fishes and a preparation method thereof. The formula of the traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 30-45 parts of allium macrostemon, 40-60 parts of semen plantaginis and 10-15 parts of star anise; drying Bulbus Allii Macrostemi, semen plantaginis, and fructus Anisi Stellati respectively, micronizing with 1000 mesh, and mixing at a certain proportion. The traditional Chinese medicine composition is non-toxic and free of side effects, improves the immunity of fishes through oral administration of the traditional Chinese medicine, and treats ichthyophthiriasis of the fishes by inhibiting and killing pathogens.
Description
Technical Field
The invention relates to a fish drug for preventing and treating ichthyophthiriasis of fishes, belongs to the technical field of aquaculture, and particularly relates to a Chinese herbal medicine formula composition capable of effectively preventing and treating ichthyophthiriasis of fishes and a preparation method thereof.
Background
The ichthyophthirius multifiliis named cryptocaryon irritans, which is a kind of hereditary ciliate (cilia spread all over the body), usually parasitizes on the body surface and gill of fish, and forms white-spotted cysts with large needles, so the ichthyophthiriasis is produced. The parasite causes abnormal activity, epithelial hyperplasia, dyspnea and mechanical damage to the fish, with subsequent infection by pathogenic bacteria. When the disease condition is serious, mucus on the body surface of the fish is increased, the body color is blackened, the fish is thin, the fish has difficulty in breathing and abnormal swimming, the fish stops eating, and the fish body rubs solid matters, so that the fish can die in batches quickly.
In nature, wild fish are rarely severely infected with the ichthyophthirius multifiliis because the host has insufficient aggregation density and the bodies of the fish are not bred enough to achieve a severe infection. However, in cement ponds, indoor aquariums, net cages of fish raft and other high-density fish culture places, insects can propagate in a large amount in a short time to cause diseases.
The method for preventing and treating ichthyophthiriasis of fish in production and aquaculture mainly adopts a method for killing pathogens, such as common mercury preparations, malachite green, formaldehyde, methyl blue and other disinfectants. However, abuse of chemical disinfectants can cause the problem of drug residues, which causes the problems of food safety and ecological safety, and the ministry of agriculture has sent out that mercury preparations and malachite green are forbidden in fish disease control, so that few methods for controlling ichthyophthiriasis are available at present. Moreover, as a result of the extensive use of disinfectants, insecticides, antimicrobial drugs, pathogenic resistance is becoming stronger.
Therefore, how to develop a safe and nontoxic fish additive as a method for preventing and treating ichthyophthiriasis is a technical problem which needs to be solved urgently by technical personnel in the field at present.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine composition for preventing and treating ichthyophthiriasis of fishes, which adopts a Chinese herbal medicine formula, is added into feed for mixing and feeding, and can effectively prevent and treat ichthyophthiriasis of fishes.
The object of the present invention is achieved by the following means.
A traditional Chinese medicine composition for preventing and treating ichthyophthiriasis is prepared from the following raw materials in parts by weight:
30-45 parts of allium macrostemon, 40-60 parts of semen plantaginis and 10-15 parts of star anise.
Furthermore, the optimal weight parts of the components in the traditional Chinese medicine composition are as follows:
40 parts of allium macrostemon, 48 parts of semen plantaginis and 12 parts of star anise.
Further, the preparation process of the traditional Chinese medicine composition for preventing and treating ichthyophthiriasis comprises the following steps:
the allium macrostemon health care tea is prepared by drying 30-45 parts of allium macrostemon, 40-60 parts of semen plantaginis and 10-15 parts of star anise respectively, carrying out 1000-mesh superfine grinding, and then uniformly mixing in proportion.
In addition, the invention also provides a using method of the traditional Chinese medicine composition for preventing and treating the ichthyophthiriasis, and the traditional Chinese medicine composition is added into daily fish feed according to the mass ratio of 1.5% and is mixed with feed for feeding.
By means of the technical scheme, the invention has the following advantages and beneficial technical effects:
1) the Chinese herbal medicine formula for preventing and treating ichthyophthiriasis of fishes is composed of pure Chinese herbal medicines, and has no toxic or side effect; the resistance of the fish is improved by taking the traditional Chinese medicine orally, and simultaneously, the ichthyophthiriasis of the fish is treated by inhibiting and killing pathogens;
2) the fish drug for preventing and treating ichthyophthiriasis of fishes belongs to a Chinese herbal medicine formula for preventing and treating ichthyophthiriasis of fishes, and can effectively prevent and treat ichthyophthiriasis of fishes when being added into feed for mixing and feeding;
3) the traditional Chinese medicine composition is non-toxic and free of side effects, improves the immunity of fishes through oral administration of the traditional Chinese medicine, and treats ichthyophthiriasis of the fishes by inhibiting and killing pathogens; is a traditional Chinese medicine formula with convenient use, good effect and no toxic or side effect.
Detailed Description
The present invention is further defined below by way of specific preferred embodiments and effect test examples, but the present invention is not limited to the following embodiments.
The traditional Chinese medicine composition for preventing and treating ichthyophthiriasis comprises the following components: 30-45 parts of allium macrostemon, 40-60 parts of semen plantaginis and 10-15 parts of star anise.
Among the above components, Bulbus Allii Macrostemi has effects of warming spleen and stomach, invigorating yang, resolving hard mass, resolving food stagnation, and killing parasite. Semen plantaginis has antibacterial and antiinflammatory effects. The star anise promotes gastrointestinal peristalsis, enhances ingestion, and can increase the number of leucocytes and improve immunity.
The allium macrostemon, the plantain seed and the star anise are all commercial products, and after the allium macrostemon, the plantain seed and the star anise are combined and formulated, a good prevention and treatment effect is achieved on the ichthyophthiriasis.
Example 1
A traditional Chinese medicine composition for preventing and treating ichthyophthiriasis of fishes is prepared from the following raw materials in parts by weight:
accurately weighing 40g of dried and crushed allium macrostemon, 48g of semen plantaginis and 12g of star anise, uniformly mixing, drying, carrying out 1000-mesh superfine crushing, and uniformly mixing according to a proportion to obtain the allium macrostemon-semen plantaginis powder.
When in use, the traditional Chinese medicine composition disclosed by the embodiment 1 of the invention is added into fish feed according to the actual situation and the mass ratio of 1.5%.
Example 2
A traditional Chinese medicine composition for preventing and treating ichthyophthiriasis of fishes is prepared from the following raw materials in parts by weight:
accurately weighing 38g of dried and crushed allium macrostemon, 52g of semen plantaginis and 10g of star anise, uniformly mixing, drying, carrying out 1000-mesh superfine crushing, and uniformly mixing according to a proportion to obtain the allium macrostemon-semen plantaginis superfine powder.
When in use, the traditional Chinese medicine composition disclosed by the embodiment 1 of the invention is added into fish feed according to the actual situation and the mass ratio of 1.5%.
Example 3
A traditional Chinese medicine composition for preventing and treating ichthyophthiriasis of fishes is prepared from the following raw materials in parts by weight:
accurately weighing 30g of dried and crushed allium macrostemon, 40g of semen plantaginis and 10g of star anise, uniformly mixing, drying, carrying out 1000-mesh superfine crushing, and uniformly mixing according to a proportion to obtain the allium macrostemon-semen plantaginis powder.
When in use, the traditional Chinese medicine composition disclosed by the embodiment 1 of the invention is added into fish feed according to the actual situation and the mass ratio of 1.5%.
Example 4
A traditional Chinese medicine composition for preventing and treating ichthyophthiriasis of fishes is prepared from the following raw materials in parts by weight:
accurately weighing 45g of dried and crushed allium macrostemon, 60g of semen plantaginis and 15g of star anise, uniformly mixing, drying, carrying out 1000-mesh superfine crushing, and uniformly mixing according to a proportion to obtain the allium macrostemon-semen plantaginis powder.
When in use, the traditional Chinese medicine composition disclosed by the embodiment 1 of the invention is added into fish feed according to the actual situation and the mass ratio of 1.5%.
Experimental examples of Effect application
Test example 1
The large yellow croaker is fed, and the experiment is set to three groups, which are arranged as follows:
a first group: adding 1.5% of the feed of example 1 into large yellow croaker;
second group: adding the feed of example 2 into feed in an amount of 1.5% to feed large yellow croakers;
third group: comparative example 1, large yellow croaker feed was normally fed without adding the Chinese medicinal composition of the present invention.
And (3) testing the fish: large yellow croaker, with about 6 halves, has ichthyophthiriasis, moderate disease condition and no serious death.
And observing and recording the ingestion condition and the body surface white spot condition of the three groups after the medicine feeding. Specific results are shown in table 1 below.
TABLE 1 Fish feeding situations of examples 1-2 and comparative example 1
As can be seen from the data in table 1 above: compared with the control group 1, the experimental group 1 and the experimental group 2 using the formula provided by the invention can reduce the white spot symptoms on the surface and gill of the fish body and promote food intake. It is fully described that: the traditional Chinese medicine composition formula provided by the invention can improve the immunity of the large yellow croaker, enhance the ingestion of the large yellow croaker and simultaneously give consideration to the insecticidal effect.
Test example 2
The experiments of feeding golden pomfret are set into three groups, and the following arrangement is adopted:
a first group: adding 1.5% of the feed of example 3 into golden pomfret;
second group: adding 1.5% of the feed of example 4 into golden pomfret;
third group: comparative example 1, large yellow croaker feed was normally fed without adding the Chinese medicinal composition of the present invention.
And (3) testing the fish: in golden pomfret, about 5 halves of golden pomfret will cause ichthyophthiriasis, mild disease and no serious death.
And observing and recording the ingestion condition and the body surface white spot condition of the three groups after the medicine feeding. Specific results are shown in table 2 below.
TABLE 2 Fish feeding situations of examples 3-4 and comparative example 1
As can be seen from the data in table 2 above: compared with the control group 1, the experimental group 1 (example 3) and the experimental group 2 (example 4) using the formula of the invention can reduce white spot symptoms on the body surface and gill of the fish, promote food intake and reduce death rate. It is fully described that: the formula of the traditional Chinese medicine composition can be absorbed by golden pompano, the immunity of the golden pompano is improved, the food intake of the golden pompano is enhanced, and the insecticidal effect is considered at the same time. The obvious effect can be seen after the composition is used for about 7 days generally.
The above description is only a preferred embodiment of the present invention, and is not intended to limit the present invention in any way, so that any simple modification, equivalent change and modification made to the above embodiment according to the technical spirit of the present invention are within the scope of the technical solution of the present invention.
Claims (2)
1. A traditional Chinese medicine composition for preventing and treating ichthyophthiriasis of fishes is characterized by being prepared from the following raw materials in parts by weight:
30-45 parts of allium macrostemon, 40-60 parts of semen plantaginis and 10-15 parts of star anise;
the allium macrostemon is prepared by drying 30-45 parts of allium macrostemon, 40-60 parts of semen plantaginis and 10-15 parts of star anise respectively, carrying out 1000-mesh superfine grinding and then uniformly mixing in proportion.
2. The traditional Chinese medicine composition for preventing and treating ichthyophthiriasis of fishes as claimed in claim 1, which comprises the following components in parts by weight: 40 parts of allium macrostemon, 48 parts of semen plantaginis and 12 parts of star anise.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201910589489.3A CN110279792B (en) | 2019-07-02 | 2019-07-02 | Traditional Chinese medicine composition for preventing and treating ichthyophthiriasis of fishes and preparation method thereof |
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| CN201910589489.3A CN110279792B (en) | 2019-07-02 | 2019-07-02 | Traditional Chinese medicine composition for preventing and treating ichthyophthiriasis of fishes and preparation method thereof |
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| CN110279792B true CN110279792B (en) | 2021-09-03 |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103623068A (en) * | 2013-11-13 | 2014-03-12 | 江西省水产科学研究所 | Drug for treating ichthyophthiriasis in fish |
| CN106728444A (en) * | 2015-11-25 | 2017-05-31 | 天津市野龙港水产养殖科技发展有限公司 | A kind of Chinese medicine composition for preventing and treating fish fresh water ich |
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- 2019-07-02 CN CN201910589489.3A patent/CN110279792B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103623068A (en) * | 2013-11-13 | 2014-03-12 | 江西省水产科学研究所 | Drug for treating ichthyophthiriasis in fish |
| CN106728444A (en) * | 2015-11-25 | 2017-05-31 | 天津市野龙港水产养殖科技发展有限公司 | A kind of Chinese medicine composition for preventing and treating fish fresh water ich |
Non-Patent Citations (2)
| Title |
|---|
| 40种中草药杀灭离体多子小瓜虫效果研究;王彬等;《广东农业科学》;20171231;第44卷(第07期);147-153 * |
| 王彬等.40种中草药杀灭离体多子小瓜虫效果研究.《广东农业科学》.2017,第44卷(第07期),147-153. * |
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Address after: 524399 No.12 Gongye South Road, Bainipo Industrial Park, Suicheng Town, Suixi County, Zhanjiang City, Guangdong Province Patentee after: Guangdong Hengxing Biotechnology Development Co.,Ltd. Address before: 524094 Jinkang Middle Road, Mazhang District, Zhanjiang City, Guangdong Province Patentee before: ZHANJIANG HENGXING CULTURE TECHNOLOGY SERVICE Co.,Ltd. |
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