CN110092786B - 吴茱萸碱的制造方法 - Google Patents
吴茱萸碱的制造方法 Download PDFInfo
- Publication number
- CN110092786B CN110092786B CN201910028395.9A CN201910028395A CN110092786B CN 110092786 B CN110092786 B CN 110092786B CN 201910028395 A CN201910028395 A CN 201910028395A CN 110092786 B CN110092786 B CN 110092786B
- Authority
- CN
- China
- Prior art keywords
- evodiamine
- formula
- compound represented
- heating
- producing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
Description
Claims (3)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2018-012737 | 2018-01-29 | ||
JP2018012737A JP7205059B2 (ja) | 2018-01-29 | 2018-01-29 | エボジアミンの製造方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN110092786A CN110092786A (zh) | 2019-08-06 |
CN110092786B true CN110092786B (zh) | 2022-10-04 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201910028395.9A Active CN110092786B (zh) | 2018-01-29 | 2019-01-11 | 吴茱萸碱的制造方法 |
Country Status (3)
Country | Link |
---|---|
JP (1) | JP7205059B2 (zh) |
CN (1) | CN110092786B (zh) |
TW (1) | TWI786258B (zh) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114262329B (zh) * | 2021-12-06 | 2023-03-31 | 合肥工业大学 | 一种吴茱萸次碱的合成方法 |
CN115141199B (zh) * | 2022-06-28 | 2023-04-07 | 江西师范大学 | 一种合成吴茱萸次碱的新方法 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107629051A (zh) * | 2017-09-27 | 2018-01-26 | 桂林理工大学 | 一种利用羰基化反应三步法合成吴茱萸碱的方法 |
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2018
- 2018-01-29 JP JP2018012737A patent/JP7205059B2/ja active Active
-
2019
- 2019-01-11 CN CN201910028395.9A patent/CN110092786B/zh active Active
- 2019-01-18 TW TW108101904A patent/TWI786258B/zh active
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107629051A (zh) * | 2017-09-27 | 2018-01-26 | 桂林理工大学 | 一种利用羰基化反应三步法合成吴茱萸碱的方法 |
Non-Patent Citations (3)
Title |
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Isolation of an amide, a possible key precursor to evodiamine, from Evodia rutaecarpa;Noboru Shoji 等;《Journal of Natural Products》;19880228;第51卷(第1期);第161-162页 * |
Quinazolinecarboline alkaloid evodiamine as scaffold for targeting topoisomerase I and sirtuins;Michael S. Christodoulou 等;《Bioorganic & Medicinal Chemistry》;20131119;第21卷(第22期);第6920-6928页,尤其是第6921页流程图1中化合物5的制备,第6924页右栏哈何物4和5的制备 * |
Studies of rutaecarpine and related quinazolinocarboline alkaloids;Bergman, Jan 等;《Journal of Organic Chemistry》;19851231;第50卷(第8期);第1246-1255页 * |
Also Published As
Publication number | Publication date |
---|---|
TWI786258B (zh) | 2022-12-11 |
CN110092786A (zh) | 2019-08-06 |
TW201932463A (zh) | 2019-08-16 |
JP7205059B2 (ja) | 2023-01-17 |
JP2019131483A (ja) | 2019-08-08 |
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Application publication date: 20190806 Assignee: Jincun (China) Co.,Ltd. Assignor: TSUMURA & CO. Contract record no.: X2019990000204 Denomination of invention: Method for producing evodiamine License type: Common License Record date: 20191126 |
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