CN110090173A - A kind of antibacterial anti-inflammatory analgesic toothpaste adding plant essence - Google Patents
A kind of antibacterial anti-inflammatory analgesic toothpaste adding plant essence Download PDFInfo
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- CN110090173A CN110090173A CN201810951975.0A CN201810951975A CN110090173A CN 110090173 A CN110090173 A CN 110090173A CN 201810951975 A CN201810951975 A CN 201810951975A CN 110090173 A CN110090173 A CN 110090173A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/25—Silicon; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/29—Titanium; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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Abstract
The invention discloses a kind of antibacterial anti-inflammatory for adding plant essence to relieve pain toothpaste, consists of the following compositions: sorbierite, hydrated silica, water, glycerol, polyethylene glycol-400, laruyl alcohol sulfuric acid ester sodium, narrow leaved tea tree essential oil, terpinene, cellulose gum, tetrasodium pyrophosphate, saccharin sodium, sodium benzoate, titanium dioxide.The toothpaste user is daily wash one's face and rinse one's mouth when can effectively remove oral bacteria using the present invention, inhibit oral bacteria cause to dental problems, without inflammation in the case where use, oral bacteria bring oral cavity, the inflammation in terms of tooth can be prevented with fresh breath；If tooth gum oral cavity is inflamed and pain, the effect of significant antibacterial anti-inflammatory and analgesic can be played.Easy to use, natural plant extracts are to human body noresidue, securely and reliably.
Description
Technical field
The present invention relates to technical field of toothpaste more particularly to a kind of antibacterial anti-inflammatory for adding plant essence to relieve pain toothpaste.
Background technique
Toothpaste is common cleaning supplies in daily life, there is very long history.With the continuous hair of science and technology
Exhibition, technological equipment continuously improve and it is perfect, various types of toothpaste are come out one after another, and the quality and grade of product is continuously improved,
Present toothpaste variety develops into great variety of goods, vdiverse in function by single clean type toothpaste, a brands up to a hundred it is multi-functional
Type toothpaste meets the needs of the different levels level of consumption.
According to the definition of toothpaste, toothpaste should comply with the following terms requirement:
(1) film and bacterial plaque that can remove dental surface are without damaging enamel and dentine；
(2) there is good cleaning oral cavity and surrounding effect；
(3) non-toxic, it is non-stimulated to oral mucosa；
(4) there are comfortable fragrance and taste, there is cool and sweet-smelling feeling after use；
(5) easy to use, at uniform, bright, soft bar when extrusion；
(6) it is easy to clean from oral cavity and on tooth, toothbrush；
(7) there is good chemically and physically stability, guarantee that indices are met the requirements of the standard in the storage phase；
(8) there is reasonable cost performance.
Existing technology is the antiphlogistic effects that Chinese medicinal herb reaches as main component, but has medicine well known to Chinese medicine
Imitate the slow and issuable toxic side effect of drug.
Summary of the invention
The present invention with the stronger ingredient of penetration natural in plant, by effective antibacterial anti-inflammatory analgesic of plant extract at
Point, the region of inflammation is reached, quickly to achieve the effect that quick sterilization anti-inflammatory analgetic.Moreover, because its pure natural plant at
Divide and does not have any side-effects to human body.Technical problems based on background technology, the invention proposes a kind of addition plants
The antibacterial anti-inflammatory of essence relieves pain toothpaste.
Technical scheme is as follows:
A kind of antibacterial anti-inflammatory analgesic toothpaste adding plant essence, consists of the following compositions: sorb (sugar) alcohol, hydration silicon
Stone, water, glycerol, polyethylene glycol-400, laruyl alcohol sulfuric acid ester sodium, plant extract elite 1, plant extract elite 2, cellulose
Glue, tetrasodium pyrophosphate, saccharin sodium, sodium benzoate, titanium dioxide.
A kind of antibacterial anti-inflammatory adding plant essence relieves pain toothpaste, by following weight percent at being grouped as: sorb
(sugar) alcohol 30-42%, hydrated silica 1-3%, water 5-10%, glycerol 12-25%, polyethylene glycol-400 1-8%, laruyl alcohol sulphur
Sour rouge sodium 1-3%, No. 1 1-5% of plant extract elite, No. 2 1-6% of plant extract elite, cellulose gum 1-3%, pyrophosphoric acid four
Sodium 0.2-1%, saccharin sodium 1-3%, sodium benzoate 1-3%, titanium dioxide surplus.
Preferably, the antibacterial anti-inflammatory of the addition plant essence relieves pain toothpaste, by following weight percent at grouping
At: sorb (sugar) alcohol 35-40%, hydrated silica 1-3%, water 5-10%, glycerol 15-20%, polyethylene glycol-400 2-5%, the moon
Cinnamic alcohol sulfuric acid ester sodium 1-3%, No. 1 1-3% of plant extract elite, No. 2 2-4% of plant extract elite, cellulose gum 1-3%, coke
Tetrasodium phosphate 0.5-0.8%, saccharin sodium 1-2%, sodium benzoate 1-3%, titanium dioxide surplus.
Preferably, the plant extract elite 1 is narrow leaved tea tree essential oil.
Preferably, the plant extract elite 2 are terpinene.
Narrow leaved tea tree (scientific name: Melaleuca ahemifolia), Myrtaceae cajeputtree mesh, xylophyta are mostly tall
Wood.Its leaf extract is commonly called as " tea tree ethereal oil " (Tea tree oil).
The narrow leaved tea tree being currently known has 236 kinds of kinds, wherein 230 kinds originate in Australia, remaining is grown in India Buddhist nun
West Asia, New Guinea, New Caledonia and Malaysia are myrtle.Melaleuca also known as thousand layers of Pterostyrax.Quilt
U.S. subtropical zone is introduced, wants that marsh is transformed with them, as a result becomes a kind of invasion Harmful species.Narrow leaved tea tree main product in
New South Wales, Australia continent north Coast.The history of discovery and existing more than 100 years of the use of Australia tea tree oil.Initially, Australia
Big Leah original inhabitant smashs or decocts the leaf of tea oil tree to pieces water and is used to treat skin disease, and later people, which gradually understand tea oil, to be had
Anti-inflammation and sterilization effect of strength.To the seven's or eight of 20th century, Australian is according to the medical value and industrial valence of tea oil
Value, by the plantation product development gradually industrialization of tea oil, in medicine, cosmetics, daily-use chemical industry, hygiene articles, women
Develop a series of new products in the fields such as conditioning liquid.
Through the statistics whole world, narrow leaved tea tree cultivated area is 20,000 hectares at that time within 2000, wherein 95% in Australian South
One line of New South Wales of the tropic, remaining is sporadicly distributed in north India, north is got over, Burma, Thailand, but yield is seldom.
2005 so far, and since Australia is influenced by global warming, narrow leaved tea tree planting area continuously meets with
By severe drought and there is desertification phenomenon, Australia narrow leaved tea tree cultivated area is reduced to 2000 hectares of (30000 mu) left and right
It can normally produce, yield only has more than 500 tons now.In international related fields, Israel and the U.S. utilize narrow leaved tea tree essential oil
Efficient, free of contamination biological organic agricultural chemical is successfully had developed to further increase to meet its large-scale production and application
Demand of the whole world to narrow leaved tea tree crude oil promotes China to rise many planting bases.
The discovery and use of Australia narrow leaved tea tree essential oil have more than 100 years history, and most of is natural mono-isolate, can
It is used in food, cosmetics and drug industry, narrow leaved tea tree essential oil has entered U.S.'s food at present, drug surveilance office " FDA " adopts
List is purchased, price is costly.
China when scientist be well understood that this essential oil have the function of strong antibacterial, bactericidal health-care effect etc. it
Afterwards, the bactericidal ingredient and non-pigmented narrow leaved tea tree essential oil draft shield of pure plant are developed on Feminine care solution field
Manage liquid, after the advent of obtain women and like.In addition scientist is in feminine hygiene wet tissue, daily-use sanitary product, skin-care product, change
Start that narrow leaved tea tree essential oil is widely applied in the industries such as cosmetic, food flavor, drug.
Terpinene is a kind of terpene.Molecular formula C10H16.It is present in cardamom oil, origanum oil and coriander oil.α-terpinene
Often existed simultaneously with γ-terpinene as mixture.α-terpinene is colourless mobility liquid, has citrus aromes.It is main to use
In manufacture essential oil and fragrance.
The invention has the beneficial effects that:
1, the present invention adds the plant extract elite of natural antibacterial anti-inflammatory analgetic in the standard for meeting national GB8372,
The plant extract elite is made of two parts；First is that the strong tonicity in plant extracts, second is that day in plant extracts
Right antibacterial anti-inflammatory analgesic component；Form the unique formula of complete antibacterial anti-inflammatory analgesic effect；Effectively prevention and improvement stomatitis
Disease and oral hygiene kill oral cavity harmful bacteria；Play the effect of prevention mouth disease.
User is daily wash one's face and rinse one's mouth when can using the present invention effectively remove oral bacteria, inhibit oral bacteria cause to ask to tooth
Topic, without inflammation in the case where use, oral bacteria bring oral cavity, the inflammation in terms of tooth can be prevented with fresh breath；Such as
Fruit tooth gum oral cavity is inflamed and pain, can play the effect of significant antibacterial anti-inflammatory and analgesic.It is easy to use, it is natural to plant
Object extract is to human body noresidue, securely and reliably.
Specific embodiment
Embodiment 1:
A kind of antibacterial anti-inflammatory adding plant essence relieves pain toothpaste, by following weight percent at being grouped as: sorb
(sugar) alcohol 38%, water 7%, glycerol 18%, polyethylene glycol-400 3%, laruyl alcohol sulfuric acid ester sodium 1.5%, is planted at hydrated silica 2%
Object skims the cream off milk No. 1 2%, plant extract elite No. 2 3%, cellulose gum 1.5%, tetrasodium pyrophosphate 0.6%, saccharin sodium
1.5%, sodium benzoate 2%, titanium dioxide surplus.
Described plant extract elite 1 is narrow leaved tea tree essential oil.
Described plant extract elite 2 are terpinene.
Embodiment 2:
A kind of antibacterial anti-inflammatory adding plant essence relieves pain toothpaste, by following weight percent at being grouped as: sorb
(sugar) alcohol 35%, water 10%, glycerol 20%, polyethylene glycol-400 2%, laruyl alcohol sulfuric acid ester sodium 1%, is planted at hydrated silica 1%
Object skims the cream off milk No. 1 3%, plant extract elite No. 2 4%, cellulose gum 1%, tetrasodium pyrophosphate 0.5%, saccharin sodium 2%, benzene
Sodium formate 3%, titanium dioxide surplus.
Described plant extract elite 1 is narrow leaved tea tree essential oil.
Described plant extract elite 2 are terpinene.
Embodiment 3:
A kind of antibacterial anti-inflammatory adding plant essence relieves pain toothpaste, by following weight percent at being grouped as: sorb
(sugar) alcohol 40%, water 10%, glycerol 15%, polyethylene glycol-400 5%, laruyl alcohol sulfuric acid ester sodium 1%, is planted at hydrated silica 1%
Object skims the cream off milk No. 1 3%, plant extract elite No. 2 2%, cellulose gum 3%, tetrasodium pyrophosphate 0.5%, saccharin sodium 2%, benzene
Sodium formate 1%, titanium dioxide surplus.
Described plant extract elite 1 is narrow leaved tea tree essential oil.
Described plant extract elite 2 are terpinene.
Embodiment 4:
A kind of antibacterial anti-inflammatory adding plant essence relieves pain toothpaste, by following weight percent at being grouped as: sorb
(sugar) alcohol 35%, hydrated silica 1.5%, water 5%, glycerol 18%, polyethylene glycol-400 2%, laruyl alcohol sulfuric acid ester sodium 1.5%,
Plant extract elite No. 1 1%, plant extract elite No. 2 4%, cellulose gum 1%, tetrasodium pyrophosphate 0.8%, saccharin sodium 1%,
Sodium benzoate 2%, titanium dioxide surplus.
Described plant extract elite 1 is narrow leaved tea tree essential oil.
Described plant extract elite 2 are terpinene.
Embodiment 5:
A kind of antibacterial anti-inflammatory adding plant essence relieves pain toothpaste, by following weight percent at being grouped as: sorb
(sugar) alcohol 38%, water 7%, glycerol 20%, polyethylene glycol-400 2.5%, laruyl alcohol sulfuric acid ester sodium 3%, is planted at hydrated silica 3%
Object skim the cream off milk No. 1 1%, plant extract elite No. 2 2.5%, cellulose gum 1%, tetrasodium pyrophosphate 0.8%, saccharin sodium 1%,
Sodium benzoate 3%, titanium dioxide surplus.
Described plant extract elite 1 is narrow leaved tea tree essential oil.
Described plant extract elite 2 are terpinene.
Comparative example 1
By the terpinene removal in embodiment 1, remaining proportion is constant.
Comparative example 2
By the narrow leaved tea tree essential oil removal in embodiment 1, remaining proportion is constant.
By the sample of embodiment 1 and comparative example 1-2, the clinical detection of gingivitis is carried out, test result is shown in Table 1:
Test method: patient respectively brushes teeth once sooner or later daily, and the usage amount of toothpaste is 5g, detects therapeutic effect after 7 days.
Therapeutic effect is divided into:
Cure: gingivitis is cured completely；
Effective: gingivitis is cured substantially, and detumescence, pain disappears substantially；
Effective: gingivitis is alleviated, and detumescence, pain is alleviated；
Invalid: alleviated gingivitis symptom is without improvement.
The following are specific therapeutic effects:
Table 1: therapeutic effect
The antibacterial anti-inflammatory of addition plant essence of the invention relieves pain toothpaste, has significant therapeutic effect to gingivitis, and mutually
Leaf Melaleuca oil and terpinene have synergy.
The foregoing is only a preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto,
Anyone skilled in the art in the technical scope disclosed by the present invention, according to the technique and scheme of the present invention and its
Inventive concept is subject to equivalent substitution or change, should be covered by the protection scope of the present invention.
Claims (5)
1. a kind of antibacterial anti-inflammatory for adding plant essence relieves pain toothpaste, which is characterized in that consist of the following compositions: sorbierite, water
Close silica, water, glycerol, polyethylene glycol-400, laruyl alcohol sulfuric acid ester sodium, plant extract elite 1, plant extract elite 2, fibre
Tie up plain glue, tetrasodium pyrophosphate, saccharin sodium, sodium benzoate, titanium dioxide.
2. the antibacterial anti-inflammatory of addition plant essence relieves pain toothpaste as described in claim 1, which is characterized in that by following weight hundred
Point ratio at being grouped as: sorbierite 30-42%, hydrated silica 1-3%, water 5-10%, glycerol 12-25%, polyethylene glycol-
400 1-8%, laruyl alcohol sulfuric acid ester sodium 1-3%, No. 1 1-5% of plant extract elite, plant extract elite No. 2 1-6%, fibres
Tie up plain glue 1-3%, tetrasodium pyrophosphate 0.2-1%, saccharin sodium 1-3%, sodium benzoate 1-3%, titanium dioxide surplus.
3. the antibacterial anti-inflammatory of addition plant essence relieves pain toothpaste as described in claim 1, which is characterized in that by following weight hundred
Point ratio at being grouped as: sorbierite 35-40%, hydrated silica 1-3%, water 5-10%, glycerol 15-20%, polyethylene glycol-
400 2-5%, laruyl alcohol sulfuric acid ester sodium 1-3%, No. 1 1-3% of plant extract elite, plant extract elite No. 2 2-4%, fibres
Tie up plain glue 1-3%, tetrasodium pyrophosphate 0.5-0.8%, saccharin sodium 1-2%, sodium benzoate 1-3%, titanium dioxide surplus.
4. the antibacterial anti-inflammatory of addition plant essence a method according to any one of claims 1-3 relieves pain toothpaste, which is characterized in that described
Plant extract elite 1 is narrow leaved tea tree essential oil.
5. the antibacterial anti-inflammatory of addition plant essence a method according to any one of claims 1-3 relieves pain toothpaste, which is characterized in that described
Plant extract elite 2 are terpinene.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810951975.0A CN110090173A (en) | 2018-08-21 | 2018-08-21 | A kind of antibacterial anti-inflammatory analgesic toothpaste adding plant essence |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810951975.0A CN110090173A (en) | 2018-08-21 | 2018-08-21 | A kind of antibacterial anti-inflammatory analgesic toothpaste adding plant essence |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110559253A (en) * | 2019-09-30 | 2019-12-13 | 曲沃李时珍医药科技有限公司 | toothpaste added with probiotics for resisting oral bacteria and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101991521A (en) * | 2010-11-03 | 2011-03-30 | 中国热带农业科学院农产品加工研究所 | Tea tree oil mouth wash and preparation method thereof |
| CN106138196A (en) * | 2016-08-24 | 2016-11-23 | 成都体九生物科技有限公司 | Toothpaste containing Radix Notoginseng extract and Radix Lamiophlomidis Rotatae extract and preparation method thereof |
-
2018
- 2018-08-21 CN CN201810951975.0A patent/CN110090173A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101991521A (en) * | 2010-11-03 | 2011-03-30 | 中国热带农业科学院农产品加工研究所 | Tea tree oil mouth wash and preparation method thereof |
| CN106138196A (en) * | 2016-08-24 | 2016-11-23 | 成都体九生物科技有限公司 | Toothpaste containing Radix Notoginseng extract and Radix Lamiophlomidis Rotatae extract and preparation method thereof |
Non-Patent Citations (3)
| Title |
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| 张倩等: "《水环境化学》", 30 June 2018, 中国建材工业出版社 * |
| 袁昌齐等: "《欧美植物药》", 30 June 2004, 东南大学出版社 * |
| 黄文达: "《香草植物就要这样玩》", 30 November 2016, 福建科学技术出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110559253A (en) * | 2019-09-30 | 2019-12-13 | 曲沃李时珍医药科技有限公司 | toothpaste added with probiotics for resisting oral bacteria and preparation method thereof |
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Application publication date: 20190806 |