KR20150040818A - Oral Hygiene functional composition and a method of manufacturing - Google Patents

Abstract

The present invention relates to a functional composition containing natural plant components and mineral salts, and a method for preparing the same, the functional composition consisting of an extract obtained by hot water extraction having ginseng, aloe, licorice, elm bark, and green tea leaf as raw materials, and a mixture mixing a peppermint leaf extract having peppermint leaf be reflux extracted with ethyl alcohol to the extract. According to the present invention, the composition especially has an excellent effect of removing oral bacteria and preventing periodontitis and gingivitis, and can achieve the effect by having the function be applied not only to the mouth, but also to foods, cosmetics, quasi-drugs, and medicines.

Description

[0001] The present invention relates to an oral hygiene functional composition and a method of manufacturing,

The present invention relates to a functional composition containing a natural plant ingredient and a mineral salt, and more particularly, to a method for manufacturing a detergent composition containing natural plant ingredients and minerals, which can be eco- .

As interest in oral hygiene has increased recently, products related to oral care have become more diverse. Oral care products are aimed at removing bad breath, inhibiting the formation of dental plaque, or preventing tooth decay.

Bad breath is typically the result of volatile sulfur compounds (VSCs) generated by microbial degradation of food residues precipitated between tooth and periodontal sac. Plaque is produced by bacterial metabolism in the mouth. It is a plaque formed by saccharides and bacteria embedded in these polysaccharides. Plaque is very sticky and not easily removed, so it is usually a major cause of periodontal disease and tooth decay. In this respect, adding antimicrobial agents to oral cleaning products can be expected to be useful for removing bad breath, inhibiting plaque formation, or preventing tooth decay.

Among many oral products, mouthwashes are one of the popular consumer products because they are useful in helping to clean and ease oral care, especially for patients undergoing dental surgery or cervical surgery. For example, there is a listerine-based oral cleanser comprising thymol manufactured by Pfizer Inc. as an active ingredient. Thymol has antimicrobial effects because it can change the cell wall of bacteria, but causes side effects such as teeth coloring, bitter taste, and mouth burning sensation (coughing sensation).

According to the saying, oral health, including teeth, is the most important factor in maintaining human life, as there is a proverb that a person's body is one thousand and one thousand teeth. The longer the age and the aging society are, the more emphasis is placed on them. It is no exaggeration to say that the degree of health of the body is determined according to the degree of oral health as well as the degree of improvement in quality of life is determined according to the absorption of all the energy source necessary for the human body through the oral cavity.

However, the teeth are not as permanent as the life of the human being is prolonged. Therefore, the causes and frequency of threatening teeth and oral health due to abrasion caused by food-borne exercise, corrosion caused by foods with high acidity and corruption caused by oral bacteria The trend is increasing day by day.

In addition, since more than 90% of external harmful substances that threaten human health such as pathogenic bacteria, environmental hormones and harmful toxins are inhaled through the oral cavity, oral health is essential to maintain the health of the body. In particular, the oral environment has optimum conditions for the growth and propagation of bacteria due to digestive enzymes and proper moisture in food waste and saliva, and it is also possible to use more than 5,000 various bacterial microorganisms including pathogenic bacteria More than a billion of these populations are observed in the oral environment.

This oral environment causes tooth decay, tooth decay, gingivitis and other inflammatory oral diseases, and bacterial spoilage of food wastes resulting in frequent mouth odors.

In general, for oral health, humans brush their teeth at least three times daily, but brushing alone can only remove about 70% of food waste and oral bacteria in the mouth.

A typical bacterium among the oral bacteria is Streptococcus mutans which causes dental caries caused by dental caries. It is virtually impossible to eradicate the tooth once it is parasitized on the tooth surface and once placed in the oral cavity.

In addition, periodontitis and gingivitis, which are typical inflammatory diseases of oral diseases, are also frequently caused by various pathogenic bacteria. Oral health care is a very important management item while people are consuming a lot of food for a lifetime and getting energy while living it. It is very troublesome to realize that it is very important to manage for oral health every time you eat. This is because it is virtually impossible to brush your teeth every time there is an increased chance of consuming food according to the environment. In order to solve these inconveniences, oral cleaning products (gum type, liquid type, etc.) which can easily manage oral health have been developed and used by many people. These oral hygiene products are showing a steady growth trend mainly in the developed countries market, which forms an aging society where quality of life and life expectancy are prolonged.

However, most of oral hygiene products currently on the market are mainly composed of fluoride compound, cetylpyridinium chloride, menthol, etc., and there is a concern about side effects that may occur in the body when they are ingested. In addition, most products are more emphasized on the removal of bad breath than tooth and oral health care.

KR 10-0681713 KR 10-1021088

In order to overcome the above-mentioned problems, the present invention has been made to solve the above-mentioned problems, and to overcome the limitation of oral health maintained by brushing, it is possible to prevent tooth decay by preventing dental caries and to prevent inflammation diseases such as periodontitis and gingivitis, In addition, research on the natural plant and mineral components that can anticipate the effects of oral odor inhibition through sterilization of oral bacteria and manufacture of dental oral cleaner containing them can improve the quality of human life through oral health The aim is to develop technology.

In order to achieve the above object, the present invention provides an extract obtained by extracting ginseng, aloe, licorice, elm bark and green tea leaves as a raw material by hot water extraction, and extracting the mint leaf with mint leaf alcohol And extracts.

In addition, the above-mentioned mixture is prepared by adding water-soluble useful ingredient extract, which is an extract of ginseng, aloe, licorice, elm bark and green tea leaves, to water in an extraction tank at a ratio of 100 times the weight of the extract, The extract was passed through a filter filter having a size of 0.5 to 1 쨉 m to remove suspended substances. The extract was filtered through a filter filter having a size of 0.5 to 1 쨉 m to remove the harmful substances from the extract. do.

In addition, the mint leaf was put into a nonwoven fabric bag and put into a shower type reflux extraction tank. The mint leaf was put into a shower type reflux extraction tank together with about 80 to 100% The extract was passed through a filter with an activated carbon filter to remove harmful components from the extract, and then the extracted extract was further extracted with 0.5-1 μm size Through which the suspended material is removed.

Further, the extract and the mint leaf extract are completely dissolved by mixing propolis, mineral sun salt, sodium fluoride, allantoin, xylitol, citric acid, sodium citrate and malic acid.

Further, the extract and the peppermint leaf extract are completely dissolved by mixing the L-menthol and glycerin.

In addition, the above production method is produced by continuously adding a mint leaf extract while stirring a natural plant mixed extract with a stirrer.

In addition, the fruit acid is prepared by mixing α-hydroxy acid (AHA) and mineral sun salt.

Also, the oral food product prepared by the method for producing a functional composition containing the natural plant ingredient and the mineral salt.

Also, cosmetics manufactured by the method for producing a functional composition containing the natural plant ingredient and the mineral salt.

Also, a quasi-drug prepared by a method for producing a functional composition containing the natural plant ingredient and the mineral salt.

Also, a medicinal product produced by the method for producing a functional composition containing the natural plant ingredient and the mineral salt.

The present invention constituted as described above is an effective ingredient showing germicidal effect of tooth decay bacteria and oral bacteria, prevention and healing effect of periodontitis and gingival inflammation, bad breath removing effect and esthetic effect, And the side effects of the chemical synthetic materials can be minimized. In addition, substances such as saponins derived from natural plants are natural surfactant components, and additional cleaning effect can be expected.

In addition, the present invention improves oral hygiene products to more natural and human-friendly products, thereby making it possible to use them safely for dental health regardless of sex, age, gender, age, By applying to oral cleaning products, Korea Ginseng can be marketed as an export strategy product as well as creating a new market for Korean ginseng product thanks to the global brand value of Korean ginseng.

1 is a photograph showing an initial stage of a sterilization test using a cleanser according to the present invention,
2 is a photograph showing a state of 30 seconds in the sterilization test using the cleaner according to the present invention,
FIG. 3 is a photograph of the state of oral bacteria observed with an optical microscope before using the oral cleanser according to the present invention,
FIG. 4 is a photograph of the state of oral bacteria observed with an optical microscope after using the oral cleanser according to the present invention. FIG.

Hereinafter, preferred embodiments of a functional composition and a method for producing a natural plant component and a mineral salt according to the present invention will be described in detail with reference to the accompanying drawings.

The functional composition containing the natural plant ingredient and the mineral salt according to the present invention and the preparation method thereof can be obtained by extracting an extract obtained by hot water extraction using ginseng, aloe, licorice, elm bark and green tea leaves as raw materials, And a mixture of mint leaf extracts refluxed with alcohol alcohol.

The natural plants used in the present invention are ginseng, aloe, licorice, elm bark, peppermint leaves, green tea leaves. The main component of ginseng is saponin, which is called ginsenoside, and it is known that it has sterilizing effect and anti-inflammatory effect against bacterial microorganisms as well as a soap base having a cleaning effect. It is also known that it contains analgesic ingredients such as pinene and strong anti-inflammatory and antimicrobial ingredients such as ocimene, panaxcinol and linoleic acid. Aloe is known to contain aloe vera, a substance that sterilizes bacteria and fungi and neutralizes toxins, and aloe vera, which is effective in the treatment of wounds and ulcers. Glycyrrhizin, which is the main ingredient, has sweetness of 4 ~ 50 times that of candy and strong surfactant effect.

It is known to release drug poisoning and has a strong anti-inflammatory effect. The elm shell is also known as milky white or yugun pei, and contains flavonoids, saponins, tannins, and mucosubstance. It is known to have excellent effects in the treatment of bacterial inflammation, purulent swelling and boils.

Mint contains a large amount of menthol, and it has a unique flavor, which not only eliminates odors in the mouth, but also has local paralysis, sterilization and preservative effects. The main component of green tea leaf is cadecin component and it is known to be effective in eliminating bad breath, and has excellent antimicrobial effect and anticorrosive effect by tooth decay. In addition, it is called natural penicillin and includes propolis substance with excellent anti-inflammation, antibacterial and bactericidal effect and sun-salt which is rich in natural minerals.

Hereinafter, a method for preparing an oral cleanser containing a natural plant-derived oil component and a mineral salt according to the present invention will be described.

1) Hot water extraction method for the useful components of ginseng, aloe, licorice, elm bark, green tea leaves

①. To remove ginseng, aloe, licorice, elm bark, soil of green tea leaves, dirt, etc., clean each raw material with water and then shred for 5 ~ 10㎜ of the raw material.

②. 1 kg of each raw material is weighed and mixed in a bag of non-woven fabric which can hold 5 kg, and then it is put into an extraction tank, and about 100 After the water is poured into the extraction tank, the extraction temperature is subjected to hot water extraction in the range of 85 to 100 ° C for about 6 hours.

③. After the hydrothermal extraction process, the remaining pesticide residues, heavy metal ions, etc. remaining in the hydrothermal extracts of 5 kinds of natural plant were passed through an activated carbon filter device, and a filtration filter having a size of 0.5 to 1 μm was installed to remove floating insoluble matter To thereby obtain a hot-water extract containing the components of ginseng, aloe, licorice, elm bark and green tea leaves used in the present invention.

2) Shower-type reflux extraction method using alcohol alcohol for the useful components of mint leaf

①. To remove soil and dirt on the leaves of mint leaves, wash them thoroughly with water, and then crush them to a size of about 5 mm in order to efficiently extract the oil component.

②. 1 kg of shredded peppermint leaves were weighed into a bag of nonwoven fabrics, and then put into a shower type refluxing tank. Then, 80 to 100% of alcohol alcohol, which was about 10 times the weight of the peppermint leaves, The alcohol is extracted under refluxing for about 3 hours at room temperature.

③. In order to remove residual pesticide residues and heavy metal ions remaining in the alcohol extract of the mint leaf, it is passed through an activated carbon filter device and then passed through a filtration device equipped with a filter having a size of 0.5 to 1 μm to remove insoluble substances suspended therein A spirits alcohol extract containing an oil component of mint leaf used in the present invention is prepared.

Hereinafter, a method for producing an oral cleanser containing a natural plant-derived oil component and a mineral sun salt will be described.

1) Ingredients and content of oral cleaning agent

Raw material name
content(%)
Input (g)
Mint Leaf Alcohol Extract
6.00
30.00
Hydrothermal extract of natural plant
73.43
367.15
Propolis
5.00
25.00
Mineral sun salt
2.00
10.00
Xylitol
5.00
25.00
Sodium fluoride
0.02
0.10
Allantoin
0.05
0.25
glycerin
8.00
40.00
α-hydroxy acid (citric acid)
0.30
1.50
Citric acid soda
0.05
0.25
Malic acid
0.10
0.50
L-menthol
0.05
0.25
Sum
100.00%
500.00

2) Method of manufacturing mouth cleaner

①. After adding the ginseng, aloe, licorice, elm bark and green tea leaf hot water extract to the beaker in a fixed amount, propolis, mineral sun salt, sodium fluoride, allantoin, xylitol, citric acid, sodium citrate and malic acid were weighed Stir well until completely dissolved.

②. In other beakers, the mint leaf alcohol alcohol extract is added in a fixed amount and then L-menthol is weighed and completely dissolved. Then, glycerin is added to the beaker to stir well.

③. Add the ② mint leaf alcohol alcohol extraction mixture solution to the water mixture of ① and ② of the natural plant hydrothermal extraction mixture and stir well until the two mixture solutions are mixed thoroughly. Particularly, it is necessary to add a mixture of alcoholic solution of peppermint leaf to the mixture of natural plant mixture. When mixed with a mixture of peppermint alcohol and alcohol, the mixed solution may be suspended.

Next, the results of the efficacy test of the oral cleaning agent prepared by using the mineral oil sunflower and the useful oil component of the natural plant will be explained.

One). Oral cleansing cocoon Streptococcus mutans Sterilization experiment.

- Experimental method

①. Streptococcus mutans was inoculated into Brain Heart Infusion (BHI) at 37 ° C (1 ° C) and diluted to 10 ⁵ to 10 ⁶ CFU / ㎖. use.

②. When 20 ml of the test solution (stock solution) is added to the test solution and mixed, the mixture is allowed to stand at room temperature for 30 seconds, and the number of bacteria is counted to determine the rate of bacterial reduction relative to the initial number of bacteria. The number of bacteria counted with sterilized physiological saline as a control is expressed as the number of initial bacteria.

③. In the initial dilution stage of all experiments, neutralization was carried out using D / E Neutralizing Broth (DIFCO). When bacteria were grown in the medium, the number of bacteria on the medium was multiplied by the dilution factor, If not, multiply by the dilution factor obtained in the neutralization step and mark it as "less than 10 (<10)".

④. Measurement of bacterial counts at all stages is carried out using Trypic Soy Agar (TSA). The viable count is calculated according to the following formula (1) and the bacterial reduction rate is determined according to the following formula (2).

(1)

 N = C X D

(N: number of viable cells, C: number of colonies (average number of two colonies), D: number of dilutions (dilution number of diluted solution))

(2)

R (%) = [(A-B) / A] X 100

(R: bacterial reduction rate, A: initial number of bacteria, B: number of bacteria after a certain time)

- Experiment result

As a result of the test, Streptococcus mutans, which is a deciduous bacterium, decreased to "<10 (less than 10) CFU / ㎖" after 30 seconds of initial inoculation [4.0 × 10 ⁵ CFU / ㎖].

(Unit: CFU / ml)
Sample name
Early
After 30 seconds
Bacterial reduction rate
Oral cleanser
4.0 X 10 ⁵
<10
99.9% or more

Streptococcus mutans sterilization test result table

One). Sterilization experiment of mouth cleaner to oral bacteria

- Experimental method

①. After the meal, rinse off the person's saliva after 2 hours, and observe the oral bacteria state before using the oral cleanser with an optical microscope.

②. 15 ml of the oral cleanser of the present invention is put into the oral cavity for 30 seconds and then the needle is taken and the state of bacteria in the oral cavity after using the oral cleanser with an optical microscope is observed.

- Experiment result

The oral cavity is the best environment for the growth of bacteria. It maintains abundant nutrients, moisture and warm and constant temperature, so more than 5,000 bacteria form more than a billion individuals. As a result of observing the state of oral bacteria before use of the oral cleanser developed in the present invention by acupuncture, it was observed that a variety of bacteria in the form of bacteria, bacillus, and sputum were active (FIG. 3).

However, when the oral cleaning agent developed in the present invention was rinsed in the oral cavity for 30 seconds, and the oral bacteria state was observed by acupuncture after spitting, various bacteria such as streptococcus, And it was observed that almost all the bacteria were killed.

While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be understood that the invention is not limited to the disclosed exemplary embodiments. On the contrary, those skilled in the art will appreciate that many modifications and variations of the present invention are possible without departing from the spirit and scope of the appended claims. And all such modifications and changes as fall within the scope of the present invention are therefore to be regarded as being within the scope of the present invention.

Claims (9)

A natural plant extract obtained by extracting it with hot water extraction using ginseng, aloe vera, licorice, elm bark and green tea leaf as a raw material and a mixture of a mixture of the above extract with a peppermint leaf extract obtained by refluxing mint leaves with alcohol And a mineral salt. The method according to claim 1,
A method for preparing a functional composition comprising a natural plant ingredient and a mineral salt, wherein the extract and the mint leaf extract are completely dissolved by mixing propolis, mineral sun salt, sodium fluoride, allantoin, xylitol, citric acid, sodium citrate and malic acid. The method according to claim 1,
A method for preparing a functional composition comprising a natural plant ingredient and a mineral salt, which are prepared by completely dissolving the extract and the L-menthol and glycerin in a mixture of the extract and the mint leaf extract. The method according to claim 1,
A method for preparing a functional composition containing a natural plant ingredient and a mineral salt, which is prepared by continuously adding a mint leaf extract while stirring a natural plant mixture extract with a stirrer. The method according to claim 1,
Wherein the fruit acid comprises a natural plant ingredient and a mineral salt prepared by mixing alpha hydroxy acid (AHA) and mineral sun salt. 6. The method according to one of claims 1 to 5,
A food for oral use produced by a method for producing a functional composition containing the natural plant ingredient and the mineral salt. 6. The method according to one of claims 1 to 5,
Cosmetics manufactured by the method for producing a functional composition containing the natural plant ingredient and the mineral salt, 6. The method according to one of claims 1 to 5,
A quasi-drug product prepared by a method for producing a functional composition containing the natural plant ingredient and the mineral salt. 6. The method according to one of claims 1 to 5,
A medicinal product produced by the method for producing a functional composition containing the natural plant ingredient and the mineral salt.

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