CN107982192A - A kind of draft nursing mouthwash of effectively removing taste - Google Patents
A kind of draft nursing mouthwash of effectively removing taste Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
- A61K8/21—Fluorides; Derivatives thereof
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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Abstract
The present invention discloses a kind of draft nursing mouthwash of effectively removing taste, green tea is rich in tea polyphenols, it can suppress the bacterial reproduction in oral cavity, and remove the foreign odor in oral cavity, honeysuckle, mulberry leaf, Radix zanthoxyli, dandelion, Sagina subulata and dried peppermint leaf have heat-clearing toxic removing, the effect of fresh breath, both extracting solutions with reference to made from Chinese gall, and sodium fluoride, glycerine, borneol, sweetener, sodium benzoate and potassium sorbate these subsidiary engine agent are dissolved in water element, the smoke of smoking generation can be removed, and the microorganism in oral cavity can be eliminated, promote canker sore healing, and taste taste and sweet mouthfeel, the sweet taste holdup time is longer, effectively oral cavity can be nursed, with safe and non-stimulating property, the advantages of breath freshening.
Description
Technical field
The present invention relates to a kind of draft of effectively removing taste to nurse mouthwash.
Background technology
The common oral care product of people is mainly toothpaste, gargle, tooth powder etc., its basic function is exactly to clean tooth,
Gum is protected, safeguards the hygiene and health in oral cavity.As the improvement of people's living standards, the health care consciousness of consumer constantly strengthens,
It it is also proposed more requirements to oral care product, requirement of the people to toothpaste and gargle is except with this basic training that cleans the teeth
The effect of some can aid in prevention mouth disease can be also add outside, therefore, toothpaste and gargle currently on the market is almost complete
All addition is for component the effect of preventing various mouth diseases, therefore oral care product both domestic and external has the production of various functions type
Product become the market mainstream, wherein being to add western medicine composition to realize mostly.
But with economic continuous development, increasingly showing the problems such as with environmental pollution, ecological disturbance, consumer
The security of product is increasingly paid close attention to, so as to increasingly advocate natural and safe product.Addition can effectively prevent various mouths
The oral care product of chamber disease Chinese herbal medicine, it is small with its toxic side effect, it is green, environmentally friendly, safe the features such as and be subject to people again
Favor, the consumption demand of in the market this kind of product constantly increasing.In addition, with the development of modernization of Chinese medicine technology, centering
The method that medicine study of active components utilizes also has obtained fine development, this is aided in for oral care product using active ingredient of Chinese herbs
Prevention mouth disease provides good technical support.
When hypersensitive dentin is that the dentine part of exposure on tooth is subject to machinery, chemistry or thermal stimulus, produce a kind of
The problem of special acid, " soft ", the symptom of pain, are the mouth diseases as caused by many reasons, present most serious is in many men
Scholar likes smoking, and it is more serious the problem of causing oral cavity to smoke, and causes smell more unpleasant.And in the market only only has
Part mouthwash be for handling the oral problem produced after smoking, and its to solve effect not obvious enough.In addition, existing market
On mouthwash to depositing insalubrity in vivo as main component, long-time service using chemical synthesis substance.There are peace
The problem of full hidden danger is high, toxic side effect is big and irritation is big.Therefore, vegetable Chinese herbal medicine is used in oral care product have become
The direction of people's research.
The content of the invention
In view of this, it is an object of the present invention to provide one kind effectively to nurse oral cavity, has safe and non-stimulating property, mouth
The draft nursing mouthwash of the pure and fresh effective removing taste of gas.
In order to solve the above-mentioned technical problem, the technical scheme is that：
A kind of draft nursing mouthwash of effectively removing taste, includes the raw material of following weight：20-30 parts of green tea,
10-16 parts of honeysuckle, 12-16 parts of mulberry leaf, 6-7 parts of Radix zanthoxyli, 17-21 parts of Sagina subulata, 8-12 parts of dried peppermint leaf, Chinese gall 7-13
Part, 11-15 parts of dandelion, 6-8 parts of sodium fluoride, 3-5 parts of glycerine, 7-9 parts of borneol, 3-5 parts of sweetener, 11-17 parts of sodium benzoate,
100-160 parts of 5-8 parts of potassium sorbate and water element.
Further, the raw material of following weight is included：30 parts of green tea, 10 parts of honeysuckle, 12 parts of mulberry leaf, Radix zanthoxyli
6 parts, 17 parts of Sagina subulata, 8 parts of dried peppermint leaf, 7 parts of Chinese gall, 11 parts of dandelion, 6 parts of sodium fluoride, 3 parts of glycerine, 7 parts of borneol, sweet taste
100 parts of 3 parts of agent, 11 parts of sodium benzoate, 5 parts of potassium sorbate and water element.
Further, the raw material of following weight is included：20 parts of green tea, 16 parts of honeysuckle, 16 parts of mulberry leaf, Radix zanthoxyli
7 parts, 21 parts of Sagina subulata, 12 parts of dried peppermint leaf, 13 parts of Chinese gall, 15 parts of dandelion, 8 parts of sodium fluoride, 5 parts of glycerine, 9 parts of borneol, sweet tea
160 parts of 5 parts of taste agent, 17 parts of sodium benzoate, 8 parts of potassium sorbate and water element.
Further, the raw material of following weight is included：25 parts of green tea, 13 parts of honeysuckle, 14 parts of mulberry leaf, Radix zanthoxyli
6.5 parts, 19 parts of Sagina subulata, 10 parts of dried peppermint leaf, 10 parts of Chinese gall, 13 parts of dandelion, 7 parts of sodium fluoride, 4 parts of glycerine, 8 parts of borneol,
130 parts of 4 parts of sweetener, 14 parts of sodium benzoate, 6.5 parts of potassium sorbate and water element.
Further, the fungicide be methylisothiazolinone, thymol, one or both of edible alcohol with
On mixture.
Further, the water element is sulphur water element.
Further, the sweetener is steviol glycoside.
Another technical problem to be solved by the invention nurses the preparation of mouthwash for a kind of draft of effectively removing taste of offer
Method, comprises the following steps：
1) 20-30 parts of fresh green tea, 10-16 parts of honeysuckle, 12-16 parts of mulberry leaf, 6-7 parts of Radix zanthoxyli, Sagina subulata 17- are taken
11-15 parts of 21 parts, 8-12 parts of dried peppermint leaf and dandelion are immersed in water purification, and are cleaned up, and are then taken out and are drained to water stain-free,
It is spare；
2) medicinal squeezer is stirred mashing in being cleaned up in step 1), mixing draft slurries is made, then
The draft solid in mixing draft slurries and draft liquid are separated using waterpower squeezer, you can draft liquid is consolidated from draft
Squeeze out and in body, finally using fractionating process, natural herb extract is isolated from draft liquid, it is spare；
3) prepared by Chinese nutgall：A, take in 7-13 parts of feeding drying units of Chinese gall and ground after drying moisture with grinder
Mill is in powder, and it is small with 40-50 DEG C of hot-water soak 24 of four times of Chinese Gall when, obtain Chinese gall leachate, it is spare；B、
Chinese gall leachate is cooled to 5-8 DEG C, activated carbon is then added into Chinese gall leachate is filtered, and Chinese gall filter is made
Liquid, it is spare；C, storng-acid cation exchange resin is added into Chinese gall filtrate, separates out the resin column containing inorganic salts, obtain
Chinese gall exchanges liquid, spare；D, make exchange liquid inject the equipment that is concentrated under reduced pressure Chinese gall to be processed, it is quiet after being concentrated under reduced pressure
Cooling is put, and Chinese nutgall is made after being filtered, it is spare；
4) fetch water in 100-160 parts of injection large beakers of element, be subsequently placed in continuous heating 5-10 minutes above alcolhol burner so that
Water element is heated to 20-40 DEG C, and adds 6-8 parts of sodium fluoride, 3-5 parts of glycerine, 7-9 parts of borneol, sweetener successively into large beaker
5-8 parts of 3-5 parts, 11-17 parts of sodium benzoate and potassium sorbate, using glass bar by manually stirring so that above-mentioned material is abundant
It is dissolved in water element, it is spare；
5) water temperature of 20-40 DEG C of water element in step 4) is kept, in addition sodium fluoride, glycerine, borneol, sweetener, benzoic acid
After sodium and potassium sorbate, take natural herb extract made from step 2) to inject in large beaker, slowly stirred clockwise with glass bar
Mix 4-6 minutes so that spare in the completely soluble element of natural herb extract；
6) by step 5) be used for heat the alcolhol burner intensity of a fire strengthen so that in large beaker the temperature of water element improve to
60-70 DEG C, then take Chinese nutgall made from step 3) to inject in large beaker, 4-6 is slowly stirred counterclockwise with glass bar
Minute so that in the completely soluble element of Chinese nutgall, and extinguish alcolhol burner, the water element in large beaker is placed naturally cold
But, it is spare；
7) water element made from step 6) is put into -10 DEG C of freezer carry out refrigeration 10-16 it is small when, carry out disinfection and kill
Bacterium, and after sterilization take out melt, with bottle it is canned after deepfreeze, to obtain the final product.
The raw material Chinese medicine of above-mentioned Chinese medicine composition：
Green tea：Rich in tea polyphenols, the effect of there is the bacterial reproduction for suppressing oral cavity, remove the foreign odor in oral cavity；
Honeysuckle：With antibacterial and antiviral efficacy；
Mulberry leaf：Containing chlorophyll, have effects that to strengthen eliminating halitosis；
Radix zanthoxyli：It is bitter, pungent；With promoting blood circulation and removing blood stasis, the effect of promoting qi circulation and relieving pain, dispelling wind and removing obstruction in the meridians, removing toxicity for detumescence；
Sagina subulata：There is expelling wind and clearing away heat, spasmolysis.
Dried peppermint leaf：Have effects that to remove halitosis, fresh breath；
Chinese gall：Have effects that antibacterial, antiviral；
Dandelion：With clearing heat and detoxicating；The effect of carbuncle that disappears dissipating bind.
For Chinese medicine composition of the present invention in Clinical practice, green tea is rich in tea polyphenols, can suppress the bacterial reproduction in oral cavity, and
The foreign odor in oral cavity is removed, being capable of counterpart intracavitary after honeysuckle, mulberry leaf, Radix zanthoxyli, dandelion, Sagina subulata and dried peppermint leaf is combined
Portion carries out the effect of heat-clearing toxic removing, fresh breath, while both extracting solutions with reference to made from Chinese gall, and sodium fluoride, glycerine,
These subsidiary engine agent of borneol, sweetener, sodium benzoate and potassium sorbate are dissolved in water element, and can not only remove smoking in use produces
Smoke, eliminate the microorganism in oral cavity, promote canker sore healing, additionally it is possible to which functions of whitening teeth and cleaning tooth stain, and gargle
Mouth of a river taste taste and sweet mouthfeel, the sweet taste holdup time is longer, nonirritant, thus oral cavity is effectively nursed, and has safe stingless
The advantages of swashing property, breath freshening.
Embodiment
Embodiment 1
A kind of draft nursing mouthwash of effectively removing taste, includes the raw material of following weight：30 parts of green tea, gold and silver
Spend 10 parts, 12 parts of mulberry leaf, 6 parts of Radix zanthoxyli, 17 parts of Sagina subulata, 8 parts of dried peppermint leaf, 7 parts of Chinese gall, 11 parts of dandelion, sodium fluoride 6
Part, 3 parts of glycerine, 7 parts of borneol, 3 parts of sweetener, 11 parts of sodium benzoate, 5 parts of potassium sorbate and 100 parts of water element.
A kind of preparation method of the draft nursing mouthwash of effectively removing taste, comprises the following steps：
1) 30 parts of fresh green tea, 10 parts of honeysuckle, 12 parts of mulberry leaf, 6 parts of Radix zanthoxyli, 17 parts of Sagina subulata, 8 parts of dried peppermint leaf are taken
It is immersed in water purification for 11 parts, and cleans up with dandelion, then takes out and drain to water stain-free, it is spare；
2) medicinal squeezer is stirred mashing in being cleaned up in step 1), mixing draft slurries is made, then
The draft solid in mixing draft slurries and draft liquid are separated using waterpower squeezer, you can draft liquid is consolidated from draft
Squeeze out and in body, finally using fractionating process, natural herb extract is isolated from draft liquid, it is spare；
3) prepared by Chinese nutgall：A, take in 7 parts of feeding drying units of Chinese gall and ground after drying moisture with grinder
In powder, and it is small with 40 DEG C of hot-water soak 24 of four times of Chinese Gall when, obtain Chinese gall leachate, it is spare；B, by five
Gall nut leachate is cooled to 5 DEG C, and activated carbon is then added into Chinese gall leachate is filtered, and Chinese gall filtrate is made, standby
With；C, storng-acid cation exchange resin is added into Chinese gall filtrate, separates out the resin column containing inorganic salts, obtain Chinese gall
Liquid is exchanged, it is spare；D, make exchange liquid inject the equipment that is concentrated under reduced pressure Chinese gall to be processed, stand after being concentrated under reduced pressure cold
But Chinese nutgall, and after being filtered is made, it is spare；
4) fetch water in 100 parts of injection large beakers of element, be subsequently placed in continuous heating 5 minutes above alcolhol burner so that water element adds
Heat adds 6 parts of sodium fluoride, 3 parts of glycerine, 7 parts of borneol, 3 parts of sweetener, 11 parts of sodium benzoate into large beaker successively to 20 DEG C
With 5 parts of potassium sorbate, using glass bar by manually stirring so that above-mentioned material is substantially soluble in water element, spare；
5) keep 20 DEG C of water temperature of water element in step 4), addition sodium fluoride, glycerine, borneol, sweetener, sodium benzoate and
After potassium sorbate, take natural herb extract made from step 2) to inject in large beaker, 4-6 is slowly stirred clockwise with glass bar
Minute so that it is spare in the completely soluble element of natural herb extract；
6) the alcolhol burner intensity of a fire for being used to heat in step 5) is strengthened so that the temperature of water element is improved to 60 in large beaker
DEG C, then take Chinese nutgall made from step 3) to inject in large beaker, be slowly stirred counterclockwise with glass bar 4-6 minutes,
So that in the completely soluble element of Chinese nutgall, and extinguish alcolhol burner, and the water element in large beaker is placed naturally and is cooled down, it is standby
With；
7) water element made from step 6) is put into -10 DEG C of freezer carry out refrigeration 10 it is small when, carry out disinfection sterilization, and
After sterilization take out melt, with bottle it is canned after deepfreeze, to obtain the final product.
In this embodiment, the fungicide is methylisothiazolinone.The water element is sulphur water element.The sweetener is
Steviol glycoside.
Embodiment 2
A kind of draft nursing mouthwash of effectively removing taste, includes the raw material of following weight：20 parts of green tea, gold and silver
Spend 16 parts, 16 parts of mulberry leaf, 7 parts of Radix zanthoxyli, 21 parts of Sagina subulata, 12 parts of dried peppermint leaf, 13 parts of Chinese gall, 15 parts of dandelion, sodium fluoride 8
Part, 5 parts of glycerine, 9 parts of borneol, 5 parts of sweetener, 17 parts of sodium benzoate, 8 parts of potassium sorbate and 160 parts of water element.
A kind of preparation method of the draft nursing mouthwash of effectively removing taste, comprises the following steps：
1) 20 parts of fresh green tea, 16 parts of honeysuckle, 16 parts of mulberry leaf, 7 parts of Radix zanthoxyli, 21 parts of Sagina subulata, dried peppermint leaf 12 are taken
15 parts of part and dandelion are immersed in water purification, and are cleaned up, and are then taken out and are drained to water stain-free, spare；
2) medicinal squeezer is stirred mashing in being cleaned up in step 1), mixing draft slurries is made, then
The draft solid in mixing draft slurries and draft liquid are separated using waterpower squeezer, you can draft liquid is consolidated from draft
Squeeze out and in body, finally using fractionating process, natural herb extract is isolated from draft liquid, it is spare；
3) prepared by Chinese nutgall：A, take in 13 parts of feeding drying units of Chinese gall and ground after drying moisture with grinder
In powder, and it is small with 50 DEG C of hot-water soak 24 of four times of Chinese Gall when, obtain Chinese gall leachate, it is spare；B, by five
Gall nut leachate is cooled to 8 DEG C, and activated carbon is then added into Chinese gall leachate is filtered, and Chinese gall filtrate is made, standby
With；C, storng-acid cation exchange resin is added into Chinese gall filtrate, separates out the resin column containing inorganic salts, obtain Chinese gall
Liquid is exchanged, it is spare；D, make exchange liquid inject the equipment that is concentrated under reduced pressure Chinese gall to be processed, stand after being concentrated under reduced pressure cold
But Chinese nutgall, and after being filtered is made, it is spare；
4) fetch water in 160 parts of injection large beakers of element, be subsequently placed in continuous heating 10 minutes above alcolhol burner so that water element adds
Heat adds 8 parts of sodium fluoride, 5 parts of glycerine, 9 parts of borneol, 5 parts of sweetener, 17 parts of sodium benzoate into large beaker successively to 40 DEG C
With 8 parts of potassium sorbate, using glass bar by manually stirring so that above-mentioned material is substantially soluble in water element, spare；
5) keep 40 DEG C of water temperature of water element in step 4), addition sodium fluoride, glycerine, borneol, sweetener, sodium benzoate and
After potassium sorbate, take natural herb extract made from step 2) to inject in large beaker, be slowly stirred 6 points clockwise with glass bar
Clock so that spare in the completely soluble element of natural herb extract；
6) the alcolhol burner intensity of a fire for being used to heat in step 5) is strengthened so that the temperature of water element is improved to 70 in large beaker
DEG C, then take Chinese nutgall made from step 3) to inject in large beaker, be slowly stirred counterclockwise with glass bar 4-6 minutes,
So that in the completely soluble element of Chinese nutgall, and extinguish alcolhol burner, and the water element in large beaker is placed naturally and is cooled down, it is standby
With；
7) water element made from step 6) is put into -10 DEG C of freezer carry out refrigeration 16 it is small when, carry out disinfection sterilization, and
After sterilization take out melt, with bottle it is canned after deepfreeze, to obtain the final product.
In the present embodiment, the fungicide is the mixture in thymol and edible alcohol.The water element is sulphur
Water element.The sweetener is steviol glycoside.
Embodiment 3
A kind of draft nursing mouthwash of effectively removing taste, includes the raw material of following weight：25 parts of green tea, gold and silver
Spend 13 parts, 14 parts of mulberry leaf, 6.5 parts of Radix zanthoxyli, 19 parts of Sagina subulata, 10 parts of dried peppermint leaf, 10 parts of Chinese gall, 13 parts of dandelion, fluorination
130 parts of 7 parts of sodium, 4 parts of glycerine, 8 parts of borneol, 4 parts of sweetener, 14 parts of sodium benzoate, 6.5 parts of potassium sorbate and water element.
A kind of preparation method of the draft nursing mouthwash of effectively removing taste, comprises the following steps：
1) 20-30 parts of fresh green tea, 10-16 parts of honeysuckle, 12-16 parts of mulberry leaf, 6-7 parts of Radix zanthoxyli, Sagina subulata 17- are taken
11-15 parts of 21 parts, 8-12 parts of dried peppermint leaf and dandelion are immersed in water purification, and are cleaned up, and are then taken out and are drained to water stain-free,
It is spare；
2) medicinal squeezer is stirred mashing in being cleaned up in step 1), mixing draft slurries is made, then
The draft solid in mixing draft slurries and draft liquid are separated using waterpower squeezer, you can draft liquid is consolidated from draft
Squeeze out and in body, finally using fractionating process, natural herb extract is isolated from draft liquid, it is spare；
3) prepared by Chinese nutgall：A, take in 7-13 parts of feeding drying units of Chinese gall and ground after drying moisture with grinder
Mill is in powder, and it is small with 40-50 DEG C of hot-water soak 24 of four times of Chinese Gall when, obtain Chinese gall leachate, it is spare；B、
Chinese gall leachate is cooled to 5-8 DEG C, activated carbon is then added into Chinese gall leachate is filtered, and Chinese gall filter is made
Liquid, it is spare；C, storng-acid cation exchange resin is added into Chinese gall filtrate, separates out the resin column containing inorganic salts, obtain
Chinese gall exchanges liquid, spare；D, make exchange liquid inject the equipment that is concentrated under reduced pressure Chinese gall to be processed, it is quiet after being concentrated under reduced pressure
Cooling is put, and Chinese nutgall is made after being filtered, it is spare；
4) fetch water in 100-160 parts of injection large beakers of element, be subsequently placed in continuous heating 5-10 minutes above alcolhol burner so that
Water element is heated to 20-40 DEG C, and adds 6-8 parts of sodium fluoride, 3-5 parts of glycerine, 7-9 parts of borneol, sweetener successively into large beaker
5-8 parts of 3-5 parts, 11-17 parts of sodium benzoate and potassium sorbate, using glass bar by manually stirring so that above-mentioned material is abundant
It is dissolved in water element, it is spare；
5) water temperature of 20-40 DEG C of water element in step 4) is kept, in addition sodium fluoride, glycerine, borneol, sweetener, benzoic acid
After sodium and potassium sorbate, take natural herb extract made from step 2) to inject in large beaker, slowly stirred clockwise with glass bar
Mix 4-6 minutes so that spare in the completely soluble element of natural herb extract；
6) by step 5) be used for heat the alcolhol burner intensity of a fire strengthen so that in large beaker the temperature of water element improve to
60-70 DEG C, then take Chinese nutgall made from step 3) to inject in large beaker, 4-6 is slowly stirred counterclockwise with glass bar
Minute so that in the completely soluble element of Chinese nutgall, and extinguish alcolhol burner, the water element in large beaker is placed naturally cold
But, it is spare；
7) water element made from step 6) is put into -10 DEG C of freezer carry out refrigeration 10-16 it is small when, carry out disinfection and kill
Bacterium, and after sterilization take out melt, with bottle it is canned after low refrigeration, to obtain the final product.
In the present embodiment, the fungicide is methylisothiazolinone, thymol, the mixture of edible alcohol.Institute
Water element is stated as sulphur water element.The sweetener is steviol glycoside.
Experimental example
The draft nursing mouthwash of effective removing taste has carried out substantial amounts of animal hypersensitive test and substantial amounts of clinical examination
Test, the use to the Chinese medicine composition provides science and objective foundation, its test method and result of the test are as follows：
First, drug poisoning is tested：
Medicine：Solution is made in the formula that the present invention uses.
Drug poisoning is tested：Select 30 Kunming kinds：The small white mouse of health, and each 15 of male and female, the equal 22-25g of weight, chooses
Rabbit 30 is selected, each 15 of male and female, the equal 2.5kg of weight, pours into small white mouse and rabbit the Chinese medicine juice of equivalent, and continuously observes 2
Hour, 2 it is small when after, there is not saliva, dead phenomenon in the belly of 30 small white mouses and 30 rabbit, thus proves, the present invention
In Chinese medicine composition have undesirable reaction produced to live body, provide guarantee for clinical test of the invention.
Two：Clinical test
Experimental subjects：The adult of 100 smokings of selection carries out clinical trial, diagnostic criteria：1st, breath freshening, in oral cavity
Bacterium significantly reduce；2nd, smoke implication concentration declines, and the bacterium in oral cavity is reduced；3rd, smoke implication concentration is without decline, oral cavity
In bacterium it is unchanged；All experimenters are randomly divided into experimental group and control group, experimental group 50, control group 50.
Treatment method：Experimental group uses the mouthwash of the application：Mouthwash 200ml made from embodiment 2, gargles 6 daily
Secondary, respectively twice, before or after meals are respectively once for Morning Afternoon Evening.It is within 2 days 1 course for the treatment of, the control group gargle with lysostaphin complex enzyme
200ml, gargles 6 times daily, and respectively twice, before or after meals are respectively once for Morning Afternoon Evening.2 days are 1 course for the treatment of.Judge to treat after using 6 days
Effect.
Criterion of therapeutical effect：
It is effective：Breath freshening, the bacterium in oral cavity significantly reduce；
Effectively：Smoke implication concentration declines, and the bacterium in oral cavity is reduced；
It is invalid：For smoke implication concentration without decline, the bacterium in oral cavity is unchanged.
Table 1 is gargle with lysostaphin complex enzyme 200ml and effective smoke abatement of the application in experimental group in control group one
The implication situation contrasting data of the draft nursing mouthwash 200ml of taste：
Table 1
Table 2 is gargle with lysostaphin complex enzyme 200ml and effective smoke abatement of the application in experimental group in control group one
The oral bacteria content contrasting data of the draft nursing mouthwash 200ml of taste：
Table 2
With reference to upper table 1-2, two groups of different experimental subjects the data obtained in same test period is contrasted, as a result table
Bright, the data measured by the draft nursing mouthwash of the effective removing taste of the application are substantially better than the molten grape ball used in control group two
Bacterium complex enzyme mouthwash, therefore, the draft nursing mouthwash of effective removing taste have a significant effect for oral care.
The Chinese medicine preparation curative effect of the present invention is further verified below by specific case：
Specific typical case 1：Gold so-and-so, man is 32 years old, addicted because smoking, and causes oral cavity to accumulate substantial amounts of cigarette stain and dense
The tobacco implication of weight, cause with so-and-so colleague for working together of gold, therefore it is military so-and-so select the toothpaste and mouthwash of fresh breath
Cleaning oral cavity is carried out, but although effect unobvious, oral cavity fresh and cool are eased, but implication becomes dense again soon, because
This, so-and-so colleague of gold is proposed with the draft nursing mouthwash of the application, with two days as a treatment course, so-and-so golden mouth after three courses for the treatment of
Gas thoroughly controls, and continues use and can keep breath freshening.
For Chinese medicine composition of the present invention in Clinical practice, green tea is rich in tea polyphenols, can suppress the bacterial reproduction in oral cavity, and
The foreign odor in oral cavity is removed, being capable of counterpart intracavitary after honeysuckle, mulberry leaf, Radix zanthoxyli, dandelion, Sagina subulata and dried peppermint leaf is combined
Portion carries out the effect of heat-clearing toxic removing, fresh breath, while both extracting solutions with reference to made from Chinese gall, and sodium fluoride, glycerine,
These subsidiary engine agent of borneol, sweetener, sodium benzoate and potassium sorbate are dissolved in water element, and can not only remove smoking in use produces
Smoke, eliminate the microorganism in oral cavity, promote canker sore healing, additionally it is possible to which functions of whitening teeth and cleaning tooth stain, and gargle
Mouth of a river taste taste and sweet mouthfeel, the sweet taste holdup time is longer, nonirritant, thus oral cavity is effectively nursed, and has safe stingless
The advantages of swashing property, breath freshening.
Certainly, the above is the representative instance of the present invention, and in addition, the present invention can also have other a variety of specific implementations
Mode, all technical solutions formed using equivalent substitution or equivalent transformation, is all fallen within the scope of protection of present invention.
Claims (8)
- A kind of 1. draft nursing mouthwash of effectively removing taste, it is characterised in that：Include the raw material of following weight：Green tea 20-30 parts, 10-16 parts of honeysuckle, 12-16 parts of mulberry leaf, 6-7 parts of Radix zanthoxyli, 17-21 parts of Sagina subulata, 8-12 parts, five times of dried peppermint leaf 7-13 parts sub-, 11-15 parts of dandelion, 6-8 parts of sodium fluoride, 3-5 parts of glycerine, 7-9 parts of borneol, 3-5 parts of sweetener, sodium benzoate 100-160 parts of 11-17 parts, 5-8 parts of potassium sorbate and water element.
- A kind of 2. draft nursing mouthwash of effectively removing taste as claimed in claim 1, it is characterised in that：Including following weight The raw material of part proportioning：30 parts of green tea, 10 parts of honeysuckle, 12 parts of mulberry leaf, 6 parts of Radix zanthoxyli, 17 parts of Sagina subulata, 8 parts, five times of dried peppermint leaf 7 parts of son, 11 parts of dandelion, 6 parts of sodium fluoride, 3 parts of glycerine, 7 parts of borneol, 3 parts of sweetener, 11 parts of sodium benzoate, 5 parts of potassium sorbate It is 100 parts plain with water.
- A kind of 3. draft nursing mouthwash of effectively removing taste as claimed in claim 1, it is characterised in that：Including following weight The raw material of part proportioning：20 parts of green tea, 16 parts of honeysuckle, 16 parts of mulberry leaf, 7 parts of Radix zanthoxyli, 21 parts of Sagina subulata, 12 parts of dried peppermint leaf, five 13 parts of gall nut, 15 parts of dandelion, 8 parts of sodium fluoride, 5 parts of glycerine, 9 parts of borneol, 5 parts of sweetener, 17 parts of sodium benzoate, potassium sorbate 8 parts and 160 parts of water element.
- A kind of 4. draft nursing mouthwash of effectively removing taste as claimed in claim 1, it is characterised in that：Including following weight The raw material of part proportioning：25 parts of green tea, 13 parts of honeysuckle, 14 parts of mulberry leaf, 6.5 parts of Radix zanthoxyli, 19 parts of Sagina subulata, 10 parts of dried peppermint leaf, 10 parts of Chinese gall, 13 parts of dandelion, 7 parts of sodium fluoride, 4 parts of glycerine, 8 parts of borneol, 4 parts of sweetener, 14 parts of sodium benzoate, sorbic acid 130 parts of 6.5 parts of potassium and water element.
- A kind of 5. draft nursing mouthwash of effectively removing taste as claimed in claim 1, it is characterised in that：The fungicide is Mixture more than one or both of methylisothiazolinone, thymol, edible alcohol.
- A kind of 6. draft nursing mouthwash of effectively removing taste as claimed in claim 1, it is characterised in that：The water element is sulphur Sulphur water element.
- A kind of 7. draft nursing mouthwash of effectively removing taste as claimed in claim 1, it is characterised in that：The sweetener is Steviol glycoside.
- A kind of 8. preparation method of the draft nursing mouthwash of effectively removing taste, it is characterised in that：Comprise the following steps：1) 20-30 parts of fresh green tea, 10-16 parts of honeysuckle, 12-16 parts of mulberry leaf, 6-7 parts of Radix zanthoxyli, Sagina subulata 17-21 are taken 11-15 parts of part, 8-12 parts of dried peppermint leaf and dandelion are immersed in water purification, and are cleaned up, and are then taken out and are drained to water stain-free, standby With；2) medicinal squeezer is stirred mashing in being cleaned up in step 1), and mixing draft slurries are made, then use Waterpower squeezer separates the draft solid in mixing draft slurries and draft liquid, you can draft liquid in draft solid Squeeze out and, finally using fractionating process, natural herb extract is isolated from draft liquid, it is spare；3) prepared by Chinese nutgall：A, take in 7-13 parts of feeding drying units of Chinese gall and be in grinder grinding after drying moisture Powder, and it is small with 40-50 DEG C of hot-water soak 24 of four times of Chinese Gall when, obtain Chinese gall leachate, it is spare；B, by five Gall nut leachate is cooled to 5-8 DEG C, and activated carbon is then added into Chinese gall leachate is filtered, and Chinese gall filtrate is made, It is spare；C, storng-acid cation exchange resin is added into Chinese gall filtrate, separates out the resin column containing inorganic salts, obtain five times Son exchanges liquid, spare；D, make exchange liquid inject the equipment that is concentrated under reduced pressure Chinese gall to be processed, stand after being concentrated under reduced pressure cold But Chinese nutgall, and after being filtered is made, it is spare；4) fetch water in 100-160 parts of injection large beakers of element, be subsequently placed in continuous heating 5-10 minutes above alcolhol burner so that water element 20-40 DEG C is heated to, and adds 6-8 parts of sodium fluoride, 3-5 parts of glycerine, 7-9 parts of borneol, sweetener 3-5 successively into large beaker 5-8 parts of part, 11-17 parts of sodium benzoate and potassium sorbate, using glass bar by manually stirring so that above-mentioned material is substantially soluble in It is spare in water element；5) keep step 4) in 20-40 DEG C of water element water temperature, addition sodium fluoride, glycerine, borneol, sweetener, sodium benzoate and After potassium sorbate, take natural herb extract made from step 2) to inject in large beaker, 4-6 is slowly stirred clockwise with glass bar Minute so that it is spare in the completely soluble element of natural herb extract；6) the alcolhol burner intensity of a fire for being used to heat in step 5) is strengthened so that the temperature of water element is improved to 60-70 in large beaker DEG C, then take Chinese nutgall made from step 3) to inject in large beaker, be slowly stirred counterclockwise with glass bar 4-6 minutes, So that in the completely soluble element of Chinese nutgall, and extinguish alcolhol burner, and the water element in large beaker is placed naturally and is cooled down, it is standby With；7) water element made from step 6) is put into -10 DEG C of freezer carry out refrigeration 10-16 it is small when, carry out disinfection sterilization, and After sterilization take out melt, with bottle it is canned after deepfreeze, to obtain the final product.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201711416391.5A CN107982192A (en) | 2017-12-22 | 2017-12-22 | A kind of draft nursing mouthwash of effectively removing taste |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201711416391.5A CN107982192A (en) | 2017-12-22 | 2017-12-22 | A kind of draft nursing mouthwash of effectively removing taste |
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| CN107982192A true CN107982192A (en) | 2018-05-04 |
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| CN201711416391.5A Withdrawn CN107982192A (en) | 2017-12-22 | 2017-12-22 | A kind of draft nursing mouthwash of effectively removing taste |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109125176A (en) * | 2018-09-28 | 2019-01-04 | 江苏瑾辉生物科技有限公司 | One kind gargle containing tea polyphenols and preparation method thereof |
| CN111728905A (en) * | 2020-06-02 | 2020-10-02 | 福州安得尔卫生技术开发有限公司 | Plant gargle |
| CN113520962A (en) * | 2021-06-18 | 2021-10-22 | 南方医科大学 | Composition for oral ecological care and preparation method and application thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103735473A (en) * | 2013-12-04 | 2014-04-23 | 何小刚 | Herbal mouthwash and preparation method thereof |
| CN105997659A (en) * | 2016-06-21 | 2016-10-12 | 江苏奇力康皮肤药业有限公司 | Anti-inflammation and anti-bacterium mouth wash |
| CN106937930A (en) * | 2017-03-07 | 2017-07-11 | 广州奥蓓斯化妆品有限公司 | A kind of herbal mouthwash and its manufacture craft for removing crock |
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2017
- 2017-12-22 CN CN201711416391.5A patent/CN107982192A/en not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103735473A (en) * | 2013-12-04 | 2014-04-23 | 何小刚 | Herbal mouthwash and preparation method thereof |
| CN105997659A (en) * | 2016-06-21 | 2016-10-12 | 江苏奇力康皮肤药业有限公司 | Anti-inflammation and anti-bacterium mouth wash |
| CN106937930A (en) * | 2017-03-07 | 2017-07-11 | 广州奥蓓斯化妆品有限公司 | A kind of herbal mouthwash and its manufacture craft for removing crock |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109125176A (en) * | 2018-09-28 | 2019-01-04 | 江苏瑾辉生物科技有限公司 | One kind gargle containing tea polyphenols and preparation method thereof |
| CN111728905A (en) * | 2020-06-02 | 2020-10-02 | 福州安得尔卫生技术开发有限公司 | Plant gargle |
| CN113520962A (en) * | 2021-06-18 | 2021-10-22 | 南方医科大学 | Composition for oral ecological care and preparation method and application thereof |
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