CN105997659A - Anti-inflammation and anti-bacterium mouth wash - Google Patents

Anti-inflammation and anti-bacterium mouth wash Download PDF

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Publication number
CN105997659A
CN105997659A CN201610451375.9A CN201610451375A CN105997659A CN 105997659 A CN105997659 A CN 105997659A CN 201610451375 A CN201610451375 A CN 201610451375A CN 105997659 A CN105997659 A CN 105997659A
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CN
China
Prior art keywords
content
combination
antiinflammatory
extract
spice
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610451375.9A
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Chinese (zh)
Inventor
吴克
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jiangsu Qilikang Skin Pharmaceutical Co Ltd
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Jiangsu Qilikang Skin Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jiangsu Qilikang Skin Pharmaceutical Co Ltd filed Critical Jiangsu Qilikang Skin Pharmaceutical Co Ltd
Priority to CN201610451375.9A priority Critical patent/CN105997659A/en
Publication of CN105997659A publication Critical patent/CN105997659A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/347Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

Abstract

The invention relates to anti-inflammation and anti-bacterium mouth wash. According to the anti-inflammation and anti-bacterium mouth wash, deionized water serves as a main ingredient, and at least a combination of magnolol, wild chrysanthemum flower extract, common andrographis herb extract and honeysuckle extract is added. According to the anti-inflammation and anti-bacterium mouth wash in the technical scheme, the mode that the magnolol, the wild chrysanthemum flower extract, the common andrographis herb extract and the honeysuckle extract are used in cooperation is adopted, the effects of rapidly diminishing inflammation, preventing gingival bleeding and effectively inhibiting oral bacteria can be achieved, and the aim of treating both symptoms and root causes is achieved.

Description

The antibacterial collutory of antiinflammatory
Technical field
The present invention relates to a kind of collutory, be specifically related to a kind of antibacterial collutory of antiinflammatory.
Background technology
Gingivitis is common periodontal tissue disease, is that tooth is by tooth owing to not noting oral hygiene Soft tartar that around thing such as food debris, antibacterial is formed and the long-time stimulus caused by tartar of hard, And incorrect oral sanitary habit, the reason such as vitamin deficiency is caused.
There is also the uneven collutory of some quality in the market, the antiinflammatory of some collutory is antibacterial Effect is poor, and the antibacterial time is shorter, it is impossible to really realize effect of anti-inflammation.
Summary of the invention
In place of the deficiencies in the prior art, it is an object of the invention to provide a kind of antibacterial collutory of antiinflammatory, It can play antiinflammatory, prevent gingival hemorrhage, effectively suppresses the purpose of oral cavity bacterium.
Technical scheme is summarized as follows:
A kind of antibacterial collutory of antiinflammatory, it is with deionized water as main component, and is at least added with Cortex Magnoliae Officinalis The combination of phenol, Flos Chrysanthemi Indici extract, Herba Andrographis extract and Flos Lonicerae extract.
Preferably, the antibacterial collutory of described antiinflammatory, wherein, the content of described magnolol be 0.1~ 0.3wt%.
Preferably, the antibacterial collutory of described antiinflammatory, wherein, the content of described Flos Chrysanthemi Indici extract is 0.1~0.3wt%.
Preferably, the antibacterial collutory of described antiinflammatory, wherein, the content of described Herba Andrographis extract is 0.1~0.3wt%.
Preferably, the antibacterial collutory of described antiinflammatory, wherein, the content of described Flos Lonicerae extract is 0.1~0.3wt%.
Preferably, the antibacterial collutory of described antiinflammatory, wherein, also include wetting agent, surfactant, Sweeting agent, spice, freshener and preservative.
Preferably, the antibacterial collutory of described antiinflammatory, wherein, described wetting agent selected from sorbitol, third Glycol or a combination thereof;The content of described wetting agent is 10~45wt%;
Described surfactant is selected from sodium lauryl sulfate, poloxamer, polysorbate or a combination thereof; The content of described surfactant is 2~5wt%;
Described sweeting agent is selected from saccharin, saccharin sodium, aspartame, stevioside, sucralose, xylitol Or a combination thereof;The content of described sweeting agent is 0.1~0.5wt%;
Described spice is selected from mint flavouring, Herba Menthae Rotundifoliae material, green tea spice, milk flavour, fruits spice Or a combination thereof;The content of described spice is 0.1~0.5wt%;
Described freshener is selected from Borneolum Syntheticum, Mentholum or a combination thereof;The content of described freshener be 0.1~ 0.3wt%;
Described preservative selected from benzoic acid, sodium benzoate, sorbic acid, potassium sorbate, methyl hydroxybenzoate, Propylparaben, butoben or a combination thereof;The content of described preservative is 0.05~0.2wt%.
The invention has the beneficial effects as follows: this case uses magnolol, Flos Chrysanthemi Indici extract, Herba Andrographis extract The mode being used in combination with Flos Lonicerae extract, it is possible to play quick antiinflammatory, prevent gingival hemorrhage, effectively Effect of suppression oral cavity bacterium, reaches the purpose for the treatment of both the principal and secondary aspects of a disease.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further detail, to make those skilled in the art join Book word can be implemented according to this as directed.
This case proposes the antibacterial collutory of antiinflammatory of an embodiment, and it is with deionized water as main component, and At least it is added with the combination of magnolol, Flos Chrysanthemi Indici extract, Herba Andrographis extract and Flos Lonicerae extract. Here Chinese medicine extract refers to use after solvent extraction Chinese medicine, then removes the solid obtained by after solvent Thing.Magnolol, Flos Chrysanthemi Indici extract, Herba Andrographis extract and Flos Lonicerae extract are interwovenesses Organic whole, generation synergistic effect of can mutually promoting between four kinds of compositions, the common collutory that improves Anti-inflammation ability.Further, the content of these four composition should be defined, specific as follows:
In the above-described embodiments, the content of magnolol is preferably 0.1~0.3wt%.
In the above-described embodiments, the content of Flos Chrysanthemi Indici extract is preferably 0.1~0.3wt%.
In the above-described embodiments, the content of Herba Andrographis extract is preferably 0.1~0.3wt%.
In the above-described embodiments, the content of Flos Lonicerae extract is preferably 0.1~0.3wt%.
As another embodiment of this case, wherein, wetting agent, surfactant, sweeting agent, perfume (or spice) are also included Material, freshener and preservative.
In this embodiment, wetting agent is selected from sorbitol, propylene glycol or a combination thereof;The content of wetting agent is 10~45wt%;
Surfactant is selected from sodium lauryl sulfate, poloxamer, polysorbate or a combination thereof;Table The content of face activating agent is 2~5wt%;
Sweeting agent selected from saccharin, saccharin sodium, aspartame, stevioside, sucralose, xylitol or its Combination;The content of sweeting agent is 0.1~0.5wt%;
Spice selected from mint flavouring, Herba Menthae Rotundifoliae material, green tea spice, milk flavour, fruits spice or its Combination;The content of spice is 0.1~0.5wt%;
Freshener is selected from Borneolum Syntheticum, Mentholum or a combination thereof;The content of freshener is 0.1~0.3wt%;
Preservative is selected from benzoic acid, sodium benzoate, sorbic acid, potassium sorbate, methyl hydroxybenzoate, Ni Bo Gold propyl ester, butoben or a combination thereof;The content of preservative is 0.05~0.2wt%.
Concrete composition and the content thereof of different embodiment listed by table one, and the surplus outside the most each composition is for going Ionized water, each composition is 100% with the summation of deionized water, omits deionized water in table one.
Table one
Embodiment 1 Embodiment 2 Embodiment 3 Embodiment 4
Magnolol 0.1wt% 0.3wt% 0.2wt% 0.1wt%
Flos Chrysanthemi Indici extract 0.1wt% 0.3wt% 0.2wt% 0.3wt%
Herba Andrographis extract 0.1wt% 0.3wt% 0.2wt% 0.1wt%
Flos Lonicerae extract 0.1wt% 0.3wt% 0.2wt% 0.3wt%
Wetting agent 10wt% 45wt% 10wt% 45wt%
Surfactant 2wt% 5wt% 2wt% 5wt%
Sweeting agent 0.1wt% 0.5wt% 0.1wt% 0.5wt%
Spice 0.1wt% 0.5wt% 0.1wt% 0.5wt%
Freshener 0.1wt% 0.3wt% 0.1wt% 0.3wt%
Preservative 0.05wt% 0.2wt% 0.05wt% 0.2wt%
This case choose porphyromonas gingivalis, Prevotella, actinomyces viscosus, escherichia coli, These five kinds of bacterium of staphylococcus aureus also carry out antibacterial experiment with reference to GB 15979-2002 appendix C 3.
Table two lists the antibacterial experiment result of embodiment 1-4.
Table two
Although embodiment of the present invention are disclosed as above, but it is not restricted to description and embodiment party Listed utilization in formula, it can be applied to various applicable the field of the invention completely, for being familiar with ability For the personnel in territory, be easily achieved other amendment, therefore without departing substantially from claim and etc. homotype Enclosing under limited general concept, the present invention is not limited to specific details and shown here embodiment.

Claims (7)

1. the antibacterial collutory of antiinflammatory, it is characterised in that it is with deionized water as main component, and At least it is added with the combination of magnolol, Flos Chrysanthemi Indici extract, Herba Andrographis extract and Flos Lonicerae extract.
The antibacterial collutory of antiinflammatory the most according to claim 1, it is characterised in that described magnolol Content is 0.1~0.3wt%.
The antibacterial collutory of antiinflammatory the most according to claim 1, it is characterised in that described Flos Chrysanthemi Indici carries The content taking thing is 0.1~0.3wt%.
The antibacterial collutory of antiinflammatory the most according to claim 1, it is characterised in that described Herba Andrographis carries The content taking thing is 0.1~0.3wt%.
The antibacterial collutory of antiinflammatory the most according to claim 1, it is characterised in that described Flos Lonicerae carries The content taking thing is 0.1~0.3wt%.
The antibacterial collutory of antiinflammatory the most according to claim 1, it is characterised in that also include wetting agent, Surfactant, sweeting agent, spice, freshener and preservative.
The antibacterial collutory of antiinflammatory the most according to claim 6, it is characterised in that described wetting agent selects From sorbitol, propylene glycol or a combination thereof;The content of described wetting agent is 10~45wt%;
Described surfactant is selected from sodium lauryl sulfate, poloxamer, polysorbate or a combination thereof; The content of described surfactant is 2~5wt%;
Described sweeting agent is selected from saccharin, saccharin sodium, aspartame, stevioside, sucralose, xylitol Or a combination thereof;The content of described sweeting agent is 0.1~0.5wt%;
Described spice is selected from mint flavouring, Herba Menthae Rotundifoliae material, green tea spice, milk flavour, fruits spice Or a combination thereof;The content of described spice is 0.1~0.5wt%;
Described freshener is selected from Borneolum Syntheticum, Mentholum or a combination thereof;The content of described freshener be 0.1~ 0.3wt%;
Described preservative selected from benzoic acid, sodium benzoate, sorbic acid, potassium sorbate, methyl hydroxybenzoate, Propylparaben, butoben or a combination thereof;The content of described preservative is 0.05~0.2wt%.
CN201610451375.9A 2016-06-21 2016-06-21 Anti-inflammation and anti-bacterium mouth wash Pending CN105997659A (en)

Priority Applications (1)

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Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
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CN105997659A true CN105997659A (en) 2016-10-12

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106580836A (en) * 2017-01-24 2017-04-26 广州薇美姿实业有限公司 Oral care composition containing plant factor and application thereof
CN106667843A (en) * 2017-01-23 2017-05-17 三椒口腔健康股份有限公司 Composition capable of inhibiting dental plaque and method for preparing mouth wash formed by composition
CN106691956A (en) * 2016-12-01 2017-05-24 李妍 Anti-inflammatory and bacteriostatic mouthwash
CN107468564A (en) * 2017-08-13 2017-12-15 何家平 A kind of blue stone toothwash hydraulic art
CN107693430A (en) * 2017-11-08 2018-02-16 江西草珊瑚消毒用品有限公司 Draft nurses one's health antibacterial gargle
CN107982192A (en) * 2017-12-22 2018-05-04 吕玲 A kind of draft nursing mouthwash of effectively removing taste
CN109363980A (en) * 2018-08-17 2019-02-22 上海涵博生物科技有限公司 A kind of antibacterial mouthwash

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CN101627965A (en) * 2009-07-21 2010-01-20 清华大学 Multifunctional pure natural mouthwash and preparation method thereof
CN103998013A (en) * 2011-12-21 2014-08-20 高露洁-棕榄公司 Heatiness and salivary secretory immunoglobulin
CN105497052A (en) * 2015-12-10 2016-04-20 苏州泽达兴邦医药科技有限公司 Compound medicine mouth wash

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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106691956A (en) * 2016-12-01 2017-05-24 李妍 Anti-inflammatory and bacteriostatic mouthwash
CN106667843A (en) * 2017-01-23 2017-05-17 三椒口腔健康股份有限公司 Composition capable of inhibiting dental plaque and method for preparing mouth wash formed by composition
CN106667843B (en) * 2017-01-23 2020-06-30 河北优固生物科技有限公司 Composition with dental plaque inhibiting effect
CN106580836A (en) * 2017-01-24 2017-04-26 广州薇美姿实业有限公司 Oral care composition containing plant factor and application thereof
CN106580836B (en) * 2017-01-24 2019-06-25 广州薇美姿实业有限公司 A kind of oral care composition and its application containing plant factor
CN107468564A (en) * 2017-08-13 2017-12-15 何家平 A kind of blue stone toothwash hydraulic art
CN107693430A (en) * 2017-11-08 2018-02-16 江西草珊瑚消毒用品有限公司 Draft nurses one's health antibacterial gargle
CN107982192A (en) * 2017-12-22 2018-05-04 吕玲 A kind of draft nursing mouthwash of effectively removing taste
CN109363980A (en) * 2018-08-17 2019-02-22 上海涵博生物科技有限公司 A kind of antibacterial mouthwash

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