CN102846517B - Traditional Chinese medicine composition capable of removing miliaria and relieving itching as well as cosmetic containing traditional Chinese medicine composition - Google Patents
Traditional Chinese medicine composition capable of removing miliaria and relieving itching as well as cosmetic containing traditional Chinese medicine composition Download PDFInfo
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- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention provides a traditional Chinese medicine composition capable of removing miliaria and relieving itching, which is composed of a folium nelumbinis extract, a folium phyllostachys extract, a honeysuckle extract and a salix leaf extract. Further, the invention particularly provides floral water containing the traditional Chinese medicine composition for removing miliaria and relieving itching. The traditional Chinese medicine composition capable of removing miliaria and relieving itching and the floral water provided by the invention have the effects of removing miliaria and relieving itching, sterilizing and preventing infantile eczema when being directly daubed on the skin, and the irritants such as alcohol, essence, pigment and mush are not added, so that the traditional Chinese medicine composition and the floral water can be used for daily skin care of infants.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition and contain the cosmetics of said composition, a kind of cosmetics that possess the Chinese medicine composition of the miliaria itching-relieving efficacies of dispelling and contain said composition particularly, a kind of cosmetics that are suitable for the antipruritic Chinese medicine composition of the miliaria of dispelling that infant uses and contain said composition more specifically.
Background technology
As a kind of traditional sanitary care article, be to be equipped with the fluid product that ethanol is made with the liquid distilled from honeysuckle flowers or lotus leaves quintessence oil at China's floral water, human body skin is had fragrance, refrigerant, effect such as the miliaria of dispelling is antipruritic.
The production of tradition floral water need add chemical substances such as ethanol, essence, pigment, only is fit to the adult and uses, if infant uses this product, has following problem:
1, the ethanol that contains in traditional floral water, essence, pigment have certain zest to human body skin, and the skin of infant own is relatively immature, and are easy to generate reactions such as allergy, discomfort.
2, ethanol belongs to dangerous materials, easily breaking out of fire danger in production, transportation, use, and infant lacks safety consciousness, is not suitable for very much using this dangerous product that has.
Therefore, the product that in the floral water product system, needs a kind of pointed, suitable infant to use.
Summary of the invention
One object of the present invention is to provide a kind of miliaria of dispelling antipruritic Chinese medicine composition, and said composition is made up of the extract of natural plants, can directly act on human body or be applied to cosmetics, has the effect that the miliaria of dispelling is antipruritic, sterilize, prevent and treat infantile eczema.
The antipruritic Chinese medicine composition of the miliaria of dispelling of the present invention, formed by the component of following mass fraction:
Folium Nelumbinis extract 1 weight portion, Folium Bambosae extract 1 weight portion, Flos Lonicerae extract 0.5-1 weight portion and Folium Salicis Babylonicae extract 0.5-1 weight portion.
The present invention's antipruritic Chinese medicine composition of miliaria of dispelling, adopt the pure natural plants extract to make, to human body safety, and have natural flavor, do not add pungents such as ethanol, essence, pigment, do not have the offensive odour of conventional extract yet, can directly be applied in skin surface and use, effect with the miliaria of dispelling, antipruritic, sterilization, control infantile eczema also can be further used for having the miliaria of dispelling, in the cosmetics of antipruritic, sterilization, control infantile eczema effect.
Another object of the present invention is to provide a kind of cosmetics that comprise the antipruritic Chinese medicine composition of the described miliaria of dispelling, a kind of floral water particularly, pungents such as this floral water is soft, essence, pigment, perfect traditional floral water is not suitable for the weak point that infant uses, and has simultaneously that the miliaria of dispelling is antipruritic, an effect of sterilization, control infantile eczema.
The invention provides a kind of cosmetics, contain the antipruritic Chinese medicine composition of the above-mentioned miliaria of dispelling.Described cosmetics can be floral water.
According to specific embodiments of the present invention, described cosmetics are a kind of floral water, comprising the antipruritic Chinese medicine composition of the above-mentioned miliaria of dispelling, can also further contain the adding ingredient of floral water routine, for example phenoxyethanol, ethylhexyl glycerol, deionized water etc.
Floral water provided by the invention comprises: by weight,
The present invention's antipruritic Chinese medicine composition 3 ~ 4% of miliaria of dispelling,
Phenoxyethanol 0.05-0.1%,
Ethylhexyl glycerol 0.05%,
The deionized water surplus.
Floral water preparation method of the present invention is: the antipruritic Chinese medicine composition of the miliaria of will dispelling adds in the deionized water, adds ethylhexyl glycerol and phenoxyethanol again, and the 1-5 ℃ of cold preservation in back that stirs was left standstill 20-24 hour.
The plant extract that the present invention adopts, be adopt the supercritical extraction technique orientation obtain and the plant of concentrating in effective composition.Wherein, the primary raw material of the used Folium Bambosae extract of the present invention is Folium Bambusae, and main component is Folium Bambosae flavone; The primary raw material of Folium Nelumbinis extract is Folium Nelumbinis, and main component is lotus flavone; The primary raw material of Flos Lonicerae extract is blade and the flower of Flos Lonicerae (Caulis Lonicerae), and main component is chlorogenic acid; The primary raw material of Folium Salicis Babylonicae extract is Folium Salicis Babylonicae, and main component is 3', 4', 5,7-luteolin.
The used plant extract carbon dioxide supercritical fluid extraction of the present invention preparation method is specific as follows:
Its technology comprises: choose fresh and tender plant leaf blade or flower → drying → pulverizing → extraction → separation → plant extract.
Concrete operation method is:
A, choose the fresh and tender plant leaf blade of high-quality or flower and clean;
B, with the blade of a or flower through 50 ℃ of dryings;
C, blade or flower are ground into 50 order powderies after the b drying;
D, will render in the extraction kettle through blade or pollen end that c obtains, and feed carbon dioxide, flow velocity is 20kg/h, and pressure is 40MPa, and temperature is 35-40 ℃, extracts, and extracts time 6-8 hour.
E, can obtain plant extract raw material of the present invention by said method.
The used raw-material pharmacological properties of the present invention is:
1) Folium Bambusae
Folium Bambusae is cool in nature, and is nontoxic, has long edible and medicinal history in China, is medicine, the dual-purpose natural plants of food of authorized by state and approval.
Folium Bambusae is record in clear " herbal classic is met former ": " Folium Bambusae master cough with dyspnea is treated muscular contracture (disease), and malignant boil kills small worm ... main cough with dyspnea person, with the heat of its energy lung heat clearing stomach also; Treat muscular contracture (disease), the malignant boil person with its gas in can incarnation also, gasifies that then bones of the body collectively is orderly and clearly, and what has the trouble of small worm." clear " medicine justice " middle record: " cold air steam is all clear for the saturating heart of Folium Bambusae delicate fragrance, little hardship.Through saying: control Wen Yiqing, the gas that specially clears away heart-fire, Ye Ruineng looses, and lightly seasoned sharp key decomposes heart channel steam.Cure mainly summer-heat and quench one's thirst, heat-phlegm in the heart, the cough with dyspnea dyspnea with rapid and short breath, all with for good agent also.Get color green grass or young crops again and go into gallbladder, gas is gone into lung clearly, is the heat with the clearing heat in QI system branch, and non-Folium Bambusae can not ... ".
Modern study:
The main component of the used Folium Bambosae extract of the present invention is Folium Bambosae flavone, and Folium Bambosae flavone can effectively be removed nitrite, and blocks the synthetic of strong carcinogen-N one nitrosamine (NMDA); Simultaneously, also have stronger bacteriostasis, salmonella typhi, gram negative bacilli and positive coccus etc. are all had certain inhibitory action.
2) Folium Nelumbinis
Folium Nelumbinis is cool in nature, and is nontoxic, has long edible and medicinal history in China, is medicine, the dual-purpose natural plants of food of authorized by state and approval.
" folk prescription proved recipe new therapy that combines both Chinese and Western medical practices a collection of selected materials " carries: Folium Nelumbinis is made charcoal, pulverization, and Oleum sesami is transferred all, is coated on the affected part, a twice-daily, the treatment impetigo has specially good effect.
" Shengji Zonglu " carries: dry Folium Nelumbinis 500 grams, 5000 milliliters of waters boil to 2500 milliliters, clean the affected part, and are coated with affected part with Rhizoma Osmundae end and oil, every day 2 times, treatment paint allergy and the dermatitis several that causes can be healed.
3) Flos Lonicerae
Flos Lonicerae is cool in nature, and is nontoxic, and China has long edible and medicinal history, is medicine, the dual-purpose natural plants of food of authorized by state and approval.
" Flos Lonicerae " one come from Compendium of Material Medica, and the sweet cold fragrance of its property can dispelling wind-heat, and also kind removing summer-heat blood poison is used for various febrile diseases, and as fever of the body, dermexanthesis, send out cards such as speckle, pyretic toxicity carbuncle sore, laryngopharynx swelling and pain, all effect is remarkable.Put down in writing according to " hall of accumulating virtue is through proved recipe ": Flos Lonicerae is controlled all toxic swellings, and paying no attention to bursts bursts, or from the beginning of heating, and the furuncle inguinal bubo, the sore throat tonsillitis: half bowl in the natural juice of Flos Lonicerae (connect stem and leaf), fry in shallow oil eight sub-services it, apply with dregs, the Tuoli that relieves internal heat, loose gas and blood, its merit solely wins.
4) Folium Salicis Babylonicae
Folium Salicis Babylonicae is cool in nature, and is nontoxic.
" the little volume of Ci Hui " controls children's's pellet, and be tired: one jin of Folium Salicis Babylonicae, and water is a pipeful of, boils and gets three liters, removes slag, and Extension washes Chi Chu, day seven, octave.
" the secret record of primary and secondary " control the soldier malignant boil, can not the name the knowledgeable: boil Folium Salicis Babylonicae if skin, wash it; But also anorexia salt.This is skin ulcer on the treatment face again.
The Chinese medicine composition that the miliaria of dispelling provided by the invention is antipruritic and floral water have the effect that the good miliaria of dispelling is antipruritic, sterilize, prevent and treat infantile eczema, and pungents such as soft, essence, pigment, perfect traditional floral water is not suitable for the weak point that infant uses.
The specific embodiment
Be further described below in conjunction with the present invention of embodiment.
Choose the fresh and tender Folium Nelumbinis of high-quality and clean, then through 50 ℃ of dryings, be ground into 50 order powderies.This Lotus Leaf is rendered in the extraction kettle, fed carbon dioxide, flow velocity is 20kg/h, and pressure is 40MPa, and temperature is 36 ℃, extracts, and extraction time remaining 7 hours obtains Folium Nelumbinis extract.
Choose high-quality fresh tender bamboo leaf and clean, then through 50 ℃ of dryings, be ground into 50 order powderies.This Folium Bambusae powder is rendered in the extraction kettle, fed carbon dioxide, flow velocity is 20kg/h, and pressure is 40MPa, and temperature is 35 ℃, extracts, and extraction time remaining 8 hours obtains Folium Bambosae extract.
Choose the fresh and tender leaf of Flos Lonicerae sheet of high-quality or flower and clean, then through 50 ℃ of dryings, be ground into 50 order powderies.This Honeysuckle Flower is rendered in the extraction kettle, fed carbon dioxide, flow velocity is 20kg/h, and pressure is 40MPa, and temperature is 38 ℃, extracts, and extraction time remaining 7 hours obtains Flos Lonicerae extract.
Choose the fresh and tender Folium Salicis Babylonicae of high-quality and clean, then through 50 ℃ of dryings, be ground into 50 order powderies.This Folium Salicis Babylonicae powder is rendered in the extraction kettle, fed carbon dioxide, flow velocity is 20kg/h, and pressure is 40MPa, and temperature is 40 ℃, extracts, and extraction time remaining 6 hours obtains the Folium Salicis Babylonicae extract.
Embodiment 1
Earlier 1g Folium Nelumbinis extract, 1g Folium Bambosae extract, 1g Flos Lonicerae extract, 0.5g Folium Salicis Babylonicae extract are stirred, obtain the present invention's antipruritic Chinese medicine composition of miliaria of dispelling.Having poured above-mentioned composition into splendid attire stirs in the agitator vessel of 96.35g deionized water; Add 0.1g phenoxyethanol and 0.05g ethylhexyl glycerol, restir is even; 1 ℃ of cold preservation was left standstill 24 hours, after the filtration filtrate packing can be obtained floral water of the present invention.
Gained floral water of the present invention carries out bacteriostatic activity through provincial health and epidemic prevention station and detects, confirmation has stronger inhibitory action (seeing Table 1) to gold-coloured staphylococci, escherichia coli, Candida albicans, salmonella typhi, helicobacter pylori, stability, bactericidal effect is good, safety non-toxic, nonirritant.
Table 1 floral water of the present invention is to the result that kills of various bacterial strains
Table 2 floral water acute oral toxicity test of the present invention result
| Dosage (mg/kg) | Mice quantity (only) | Death toll (only) | Mortality rate (%) |
| ?1000 | 10 | 0 | 0 |
| ?3000 | 10 | 0 | 0 |
| ?5000 | 10 | 0 | 0 |
| ?10000 | 10 | 0 | 0 |
Floral water of the present invention is to chmice acute per os LD
50＞10000mg/kg by the classification of chemical substance acute toxicity, belongs to actual nontoxic level.
The embodiment of the invention 1 gained floral water is used for the treatment of the facial miliaria of infant totally 20 examples, the age of institute's subject infant be 10 ~ 24 months big, get floral water of the present invention and be applied to the affected part in right amount:
Used first day, and saw that obviously infant scratched 18 examples that have that the action of facial affected part reduces.
Used second day, miliaria obviously reduces, and does not scratch infant 20 examples of action substantially.
Used the 3rd day, miliaria does not observe substantially, and all infant are not all scratched the affected part action.
Illustrate that floral water of the present invention has the antipruritic function of the miliaria of dispelling, and can substitute the like product that contains hormone.Do not see any untoward reaction eventually from beginning to be applied to.
Embodiment 2
Earlier 1g Folium Nelumbinis extract, 1g Folium Bambosae extract, 0.5g Flos Lonicerae extract, 0.5g Folium Salicis Babylonicae extract are stirred, obtain the present invention's antipruritic Chinese medicine composition of miliaria of dispelling.Having poured above-mentioned composition into splendid attire stirs in the agitator vessel of 96.9g deionized water; Add 0.05g phenoxyethanol and 0.05g ethylhexyl glycerol, restir is even; 3 ℃ of cold preservations were left standstill 20 hours, after the filtration filtrate packing can be obtained floral water of the present invention.
The embodiment of the invention 2 gained floral water are used for the treatment of the facial eczema of children's for 20 examples, the age of institute's subject infant be 10 ~ 24 months big, get floral water of the present invention and be applied to the affected part in right amount:
Used first day, infant is scratched 15 examples that have of action minimizing, and the red and swollen variation in affected part is all not obvious.
Used the 3rd day, the affected part redness is obviously improved, and infant is scratched 18 examples that have of action minimizing.
Used the 5th day, the facial eczema of children's disappears substantially 19 examples, and an infant eczema symptom obviously alleviates.
Illustrate that floral water of the present invention possesses the effect of the infantile eczema of preventing and treating, and do not see any untoward reaction eventually from beginning to be applied to.
Embodiment 3
Earlier 1g Folium Nelumbinis extract, 1g Folium Bambosae extract, 1g Flos Lonicerae extract, 1g Folium Salicis Babylonicae extract are stirred, obtain the present invention's antipruritic Chinese medicine composition of miliaria of dispelling.Having poured above-mentioned composition into splendid attire stirs in the agitator vessel of 95.85g deionized water; Add 0.1g phenoxyethanol and 0.05g ethylhexyl glycerol, restir is even; 5 ℃ of cold preservations were left standstill 23 hours, after the filtration filtrate packing can be obtained floral water of the present invention.
Claims (5)
1. the Chinese medicine composition that the miliaria of dispelling is antipruritic is characterized in that, is made up of the component of following mass fraction:
Folium Nelumbinis extract 1 weight portion, Folium Bambosae extract 1 weight portion, Flos Lonicerae extract 0.5-1 weight portion and Folium Salicis Babylonicae extract 0.5-1 weight portion;
Described plant extract adopts the carbon dioxide supercritical extraction method preparation; Preparation technology comprises: choose fresh and tender plant leaf blade or flower → drying → pulverizing → extraction → separation → plant extract;
The concrete preparation method of described plant extract is:
A, choose the fresh and tender plant leaf blade of high-quality or flower and clean;
B, with the blade of a or flower through 50 ℃ of dryings;
C, blade or flower are ground into 50 order powderies after the b drying;
D, will render in the extraction kettle through blade or pollen end that c obtains, and feed carbon dioxide, flow velocity is 20kg/h, and pressure is 40MPa, and temperature is 35-40 ℃, extracts, and extracts time 6-8 hour, obtains plant extract.
2. cosmetics is characterized in that, contain the antipruritic Chinese medicine composition of the described miliaria of dispelling of claim 1.
3. cosmetics according to claim 2 is characterized in that, cosmetics are floral water.
4. cosmetics according to claim 3 is characterized in that, by weight percentage, comprising:
The Chinese medicine composition 3～4% that the described miliaria of dispelling of claim 1 is antipruritic,
Phenoxyethanol 0.05-0.1%,
Ethylhexyl glycerol 0.05%,
The deionized water surplus.
5. according to the preparation method of the described cosmetics of claim 4, it is characterized in that the Chinese medicine composition that the miliaria of dispelling is antipruritic is poured in the deionized water, add ethylhexyl glycerol and phenoxyethanol, stir evenly the 1-5 ℃ of cold preservation in back and left standstill 20-24 hour.
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| CN 201210364562 CN102846517B (en) | 2012-09-26 | 2012-09-26 | Traditional Chinese medicine composition capable of removing miliaria and relieving itching as well as cosmetic containing traditional Chinese medicine composition |
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| CN 201210364562 CN102846517B (en) | 2012-09-26 | 2012-09-26 | Traditional Chinese medicine composition capable of removing miliaria and relieving itching as well as cosmetic containing traditional Chinese medicine composition |
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| CN104606559B (en) * | 2015-02-13 | 2017-10-31 | 管天球 | A kind of Camellia Leaves antipruritic |
| CN107496498A (en) * | 2017-08-30 | 2017-12-22 | 浙江天多好环保科技有限公司 | It is a kind of to treat sensitive skin, the emulsifiable paste and preparation method thereof of eczema |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1418617A (en) * | 2001-12-26 | 2003-05-21 | 蔡兰泉 | Preparation of body-building disease-removing bath foam |
| CN101757401A (en) * | 2008-12-09 | 2010-06-30 | 景午辰 | Traditional Chinese medicine preparation for treating skin itch |
| CN101884608A (en) * | 2010-07-09 | 2010-11-17 | 天津郁美净集团有限公司 | Mosquito repelling composition |
| CN102247442A (en) * | 2011-06-13 | 2011-11-23 | 北京华夏众芳生物科技有限公司 | Traditional Chinese medicine composition and preparation with mosquito repelling and itching relieving efficacies, and preparation method thereof |
| CN102293967A (en) * | 2011-09-22 | 2011-12-28 | 郭心仪 | Medicine for treating eczema |
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Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1418617A (en) * | 2001-12-26 | 2003-05-21 | 蔡兰泉 | Preparation of body-building disease-removing bath foam |
| CN101757401A (en) * | 2008-12-09 | 2010-06-30 | 景午辰 | Traditional Chinese medicine preparation for treating skin itch |
| CN101884608A (en) * | 2010-07-09 | 2010-11-17 | 天津郁美净集团有限公司 | Mosquito repelling composition |
| CN102247442A (en) * | 2011-06-13 | 2011-11-23 | 北京华夏众芳生物科技有限公司 | Traditional Chinese medicine composition and preparation with mosquito repelling and itching relieving efficacies, and preparation method thereof |
| CN102293967A (en) * | 2011-09-22 | 2011-12-28 | 郭心仪 | Medicine for treating eczema |
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