CN107648494A - One kind treats gingivitis and canker sore Chinese medical collutory and preparation method thereof - Google Patents
One kind treats gingivitis and canker sore Chinese medical collutory and preparation method thereof Download PDFInfo
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- CN107648494A CN107648494A CN201711029850.4A CN201711029850A CN107648494A CN 107648494 A CN107648494 A CN 107648494A CN 201711029850 A CN201711029850 A CN 201711029850A CN 107648494 A CN107648494 A CN 107648494A
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- Cosmetics (AREA)
Abstract
The present invention relates to one kind to treat gingivitis and canker sore Chinese medical collutory and preparation method thereof, belongs to drug preparation technique field；The Chinese medical collutory is made up of 5 10 parts of Chinese anise, 10 20 parts of elscholtiza, 25 35 parts of peppermint, 5 15 parts of honeysuckle, 15 25 parts of lophatherum gracile, 10 20 parts of catechu, 38 parts of radix glycyrrhizae, 3000 parts of water；Its preparation method is by 5 15 grams of extracting honeysuckle, 15 25 grams of lophatherum gracile, 10 20 grams of catechu, the mixing of 38 grams of radix glycyrrhizae, adds 3000 milliliters of water, with being cooked by medium heat after being boiled by fire, maintains 100 DEG C of temperature, decocts half an hour；5 10 grams of Chinese anise, 10 20 grams of elscholtiza, 25 35 grams of peppermint are added, continues to boil to remaining 1600 milliliters of liquid；Take the Chinese medicinal liquor to add 400 milliliters of rice wine 50 degree after being cooled to 25 DEG C, be distributed into 200 milliliters one bottle, produce gargle；The gargle can be effectively improved the performance directly perceived of oral cavity disease and tongue fur, and the Chinese medicine of the gargle integration of drinking and medicinal herbs, in good taste, occupation mode is easy, without any side effects, and safety coefficient is high.
Description
Technical field
The present invention relates to a kind of Chinese medical collutory, and in particular to a kind of Chinese medical collutory for treating gingivitis and canker sore
And preparation method thereof, belong to drug preparation technique field.
Background technology
One of the approach of oral cavity as pathogenic microorganism invasion human body, in resistance of human body decline, underlying diseases breaking-out etc.
Under the influence of the factors such as integral status and topical health are bad, often occur halitosis, mouth be viscous, canker sore, tooth with illnesss such as inflammation,
Severe patient influences appetite, digestion, influences notice and mood, and even pulmonary infection, throat are caused for some severe cases
The possibility of the complication such as inflammation, gastritis.
The concern because of personal image and various factors cause the increase of oral cavity partial discomfort crowd, some crowds couple in recent years
The performance directly perceived of oral cavity disease and tongue fur is also paid attention to earlier above, thus oral cavity disease is badly in need of improving, and the appearance of all kinds of mouthwashes is just
Embody this demand.Present market and the Western medicine collutory clinically largely used, spray etc., chemicals it is chronic
Toxicity, often patient is set to give up halfway；Chlorohexidene is gargled the with a long history of hydraulic control bacterial plaque, and effect is more affirmed, but chlorohexidene
It is middle because having the shortcomings that to make tooth dyeing, bitter, be subject to certain restrictions its clinical practice.And contain bactericide in chlorohexidene
Chlorhexidine, chlorhexidine have stronger excitant, larger to eye conjunctiva stimulation, and children and young oral cavity occur Silent Neuritis superficial and taken off
Bits infringement, allergic reaction may also can be produced after use of being grown up, limitation or systemic nettle rash occurs, can also had cough, roar
Asthma, expiratory dyspnea, stomachache, papebral conjunctiva oedema, shock etc. are reacted.In addition because containing anion surfactant in toothpaste, its with
Chlorhexidine produces incompatibility, therefore using at least needing can just brush teeth after the oral preparation of this product within 30 minutes.Some Chinese medicine mouth washs
The Chinese medicine used can not be long-term use of, because of its toxic side effect, renal toxicity etc..
CN03117479.5 discloses be addicted to drink Crowded health protection product additive and product, it is characterised in that is used from vegetable material
Solvent extraction active ingredient is as additive, although also containing in 73 kinds of plants such as the Longstamen Onion Bulb of its vegetable material composition, lily, Chinese cassia tree
There are Chinese anise, honeysuckle, elscholtiza, lophatherum gracile, peppermint, ramulus acaciae, radix glycyrrhizae etc., but because its constituent is more, drug ratio
Difference, required manufacture craft is more complicated, and curative effect does not protrude, the effect without obvious treatment gingivitis and canker sore.
CN201210489456.x, which discloses balance intestinal Bacterial community, improves complete nutritional composition and the application of metabolic syndrome, its group
Compound includes containing Chinese anise, honeysuckle, elscholtiza, lophatherum gracile, thin in the 100 numerous food components such as full cereal, peanut, nut
Lotus, ramulus acaciae, radix glycyrrhizae etc., but its composition species is more, and curative effect is different, non-to be directed to gingivitis and canker sore.
In summary, current technology makes its effect be greatly affected because of various deficiencies, develops a kind of instruction of Chinese Medicine theory
The treatment gingivitis and the Chinese medical collutory of canker sore that prescription is rigorous, flavour of a drug are reduced the number of, curative for effect are very necessary.
The content of the invention
It is an object of the invention to provide one kind to improve oral cavity hot gas sense, tooth with bleeding, glossalgia, the swelling and pain of tooth dental caries, dry throat, pharyngalgia
And the Chinese medical collutory of the symptom such as yellowish fur, gonorrhoea.The gargle can be effectively improved the table directly perceived of oral cavity disease and tongue fur
It is existing, and the gargle is in good taste, occupation mode is easy, without any side effects, safety coefficient is high.
To realize the purpose of foregoing invention, the technical scheme that the present invention takes is as follows：
One kind treats gingivitis and canker sore Chinese medical collutory, is made up of the component of following parts by weight：
Chinese anise 5-10 parts, elscholtiza 10-20 parts, peppermint 25-35 parts, honeysuckle 5-15 parts, lophatherum gracile 15-25 parts, catechu 10-
20 parts, radix glycyrrhizae 3-8 parts, 3000 parts of water.
It is a further object to provide a kind of preparation method for treating gingivitis and canker sore Chinese medical collutory,
Comprise the following steps：
（1）Extracting honeysuckle 5-15 parts, lophatherum gracile 15-25 parts, catechu 10-20 parts, the mixing of radix glycyrrhizae 3-8 parts, add 3000 parts of water, with big
Fire is cooked by medium heat after boiling, and maintains 100 DEG C of temperature, decocts half an hour；
（2）Chinese anise 5-10 parts, elscholtiza 10-20 parts, peppermint 25-35 parts are added, continues to boil to remaining 1600 parts of liquid；
（3）Take the Chinese medicinal liquor to add 50 degree of 400 milliliters of rice wine after being cooled to 25 DEG C, be distributed into 200 milliliters one bottle, produce to contain and gargle
Liquid.
The effect of each component and effect are as follows：
Chinese anise：It is pungent, temperature, gas fragrance, savory sweet tea.《Book on Chinese herbal medicine is just》Record its energy：" remove teeth mouth disease, lower gas, removing toxic substances." it is pungent
The effect of warm cold dispelling has the effect of fine for Buccodental disease, and fragrant odour can make breath freshening.Pharmacological evaluation proves eight
The ethanol extract of erect hypecoum is to staphylococcus aureus, pneumococcus, corynebacterium diphtheriae, hay bacillus, comma bacillus, typhoid fever bar
Bacterium, paratyphosum Bacterium, shigella dysenteriae, Escherichia coli and Common Pathogenic dermatophyte have stronger inhibitory action.
Honeysuckle：It is clearing heat and detoxicating, wind-heat dissipating.《Book on Chinese herbal medicine is newly organized》It is " the superb work of sterilization to carry honeysuckle.Not into poison then
Dissipate, then disappear into poison, goner can give birth to, and bad person can turn.Therefore ulcer carbuncle on the back, must be using this medicine as the pellet for taking life by force.But its taste is pure good,
Property tonifying yin again, though kind sterilization, and function is very slow, it is necessary to uses it greatly." honeysuckle flower is sweet cold in nature, fragrant odour, both can clear thin table,
And can solution noxious heat in the blood system, for carbuncle swells furunculosis, larynx numbness, erysipelas, toxic-heat and blood stasis, anemopyretic cold, warm disease heating.
Elscholtiza：Inducing sweat and dispelling exogenous evils, and middle dampness removing.Wang Ying《Food book on Chinese herbal medicine》：" Xia Yue boils drink for tea, can adjust medium temperature without pyreticosis
Stomach；Gargled containing juice, remove foul smell.”
Lophatherum gracile：Clearing away the heart-fire, relieving restlessness heat, diuresis.It is thirsty to control pyreticosis, vexed, hot urination, stranguria with turbid discharge, aphthous stomatitis tongue boil, gum swells
Bitterly.
Peppermint：Dispelling wind-heat.Refresh oneself, promoting eruption.For anemopyretic cold, wind-warm syndrome is from the beginning of, headache, hot eyes, larynx numbness, aphtha,
Rubella, measles, Breast bilges frowsty.《A thousand pieces of gold food therapy》：" but kidney qi, it is clean to make us implication perfume (or spice).The main poison that exorcises evil spirits, except labor disadvantage.”《Detailed outline》：
" all diseases of throat, ability to speak.Control scrofula, sore scabies, wind scabies urticaria." lophatherum gracile has antivirus action, have to viral ECHO11 strains
Inhibitory action；There are anti-irritant, antitussive action simultaneously：The anti-irritant effect of menthol causes tracheae to produce new secretion, and makes thick
Thick mucus is easy to discharge, therefore has phlegm-dispelling functions, also has been reported that menthol has good antitussive action to cavy and per capita；Also
Bactericidal action：Menthol has a very strong bactericidal action, and d- menthols are stronger than the bacteriostasis of 1- menthol.
Ramulus acaciae：Heat-clearing, resolving sputum, hemostasis, help digestion, myogenic, analgesic therapy.Phlegm-heat cough is controlled, is quenched one's thirst, is spitted blood, bleeding from five sense organs or subcutaneous tissue, hematuria,
Bloody flux, metrorrhagia, children's indigestion, noma, aphtha, larynx numbness, wet sore.“《Book on Chinese herbal medicine is just》：Fall fire is promoted the production of body fluid, and clear sputum cough, controls mouth
Sore larynx numbness, dysphoria with smothery sensation, only quenches one's thirst, and spits blood, bleeding from five sense organs or subcutaneous tissue, has blood in stool, hematuria, hygropyretic dysentery blood, and married woman collapses leaching, and menses are more than, children's infantile malnutrition due to digestive disturbances or intestinalparasites heat,
Aphthae in children, herpes simplex, wet rotten all sores, hold back flesh and put on flesh, also kill parasites.”
Radix glycyrrhizae：It is clearing heat and detoxicating, moisten the lung and relieve the cough, coordinating the drug actions of a prescription；Honey-fried licorice root can invigorate the spleen and benefit qi.Abscess of throat is cured mainly, is coughed, taste are empty
It is weak, taste-blindness rate, hepatitis, hysteria, carbuncle furuncle poison, medicine and food poisoning.Anti-inflammatory and antiallergic action：Radix glycyrrhizae time
Granuloma induced by implantation of cotton pellets of the acid to big white mouse, formaldehyde edema, tuberculin reaction, subcutaneous granulation capsule inflammation have inhibitory action.
What ammonium glycyrrhetate, Sodium glycyrrhetinate can effectively influence subcutaneous granulation capsule inflammation oozes out phase and proliferative phase, and its action intensity is weaker than
Or close to cortisone.Radix glycyrrhizae has phlegm-dispelling functions, can promote throat and bronchial secretion, phlegm is easily brought up.Enoxolone
Derivative has significant antitussive effect to the trial cough of cavy and cat.
【Character】This product is brown liquid.
【Function is with curing mainly】
Treat function：Oral cavity hot gas sense, tooth can be effectively improved with bleeding, glossalgia, the swelling and pain of tooth dental caries, dry throat, pharynx
The symptom such as pain and yellowish fur, gonorrhoea.
【Usage and dosage】20 milliliters every time, containing gargling 3 minutes.
【Pay attention to】Pregnant woman and children, which avoid, to drink.
The beneficial effects of the invention are as follows：Chinese anise warming middle-JIAO for eliminating dampness in this product, the strong fortune of taste, wet turbid oral cavity general without more than.
Honeysuckle is clearing heat and detoxicating, kills except bacterium in oral cavity, can fundamentally clean oral cavity, keeps the balance of internal environment of oral cavity.Elscholtiza is adjusted
Medium temperature stomach, remove implication.Lophatherum gracile clearing away the heart-fire, relieving restlessness heat, it is thirsty to control pyreticosis, aphthous stomatitis tongue boil, swelling and aching of gum.Peppermint surname dissipate wind
Heat, hot gas in mouth is removed, makes implication perfume (or spice) clean.Ramulus acaciae has to improve well for mouth diseases such as noma, aphtha, larynx numbness to be made
With.Radix glycyrrhizae coordinating the drug actions of a prescription, while have certain effect to abscess of throat, cough etc..Gargle after boiling not only can substantially change
Kind canker sore, gingivitis, remove halitosis, eliminate thick greasy tongue fur, to mouth diseases such as periodontitis, gingivitis, canker sore all
There is certain Prevention effect；And this product is using the Chinese medicine of integration of drinking and medicinal herbs as primary raw material, it then follows safely, effectively, can
The principle of control, side effect will not be produced to human body, can be long-term use of.
In order to prove the effect of the present invention, situation is improved with Oral symptoms before and after gargle using observation patient and carried out pair
Than experiment.Experimental method and result are as follows：
Raise damp and hot tongue picture patient 20, wherein male 14, women 6, equal foundation-free disease.Positive controls are connected using silver
Gargle,（Prepared for The First Affiliated Hospital of Guangzhou University of Traditional Chinese Med, authentication code：101025）, gargle sample sets.Patient three
It is appropriate containing medicine is gargled before rear before the meal and sleep（20 milliliters or so）About 3 minutes in mouth.It is every during experiment to need first clear water after the meal
Gargle once, remove food residual in oral cavity, clean oral cavity.Subject avoids pungent food during testing, the food of damp and hot property, whole
Individual process need not change other habits and customs.It is 5 days to observe the course for the treatment of.According to clinical symptom characteristic, with dry, bitter taste, mouth it is light,
The projects such as salty taste, mouth are viscous, bleeding gums, swelling and aching of gum are symptom objects of statistics.Symptom describes：Without=0;Gently=1；In=2；Weight=3,
It the results are shown in Table 1 and table 2.
Test result indicates that：Sample gargle swells in dry, bitter taste, halitosis, oral cavity hot gas sense, glossalgia, bleeding gums, gum
Bitterly, with more all being improved before treatment in multiple symptoms such as dry throat, pharyngalgia, and silver connects gargle in identical disease project
Overall curative effect does not have sample port is clean to gargle improvement substantially.
Embodiment
The present invention is described in further details below by example, these examples are only used for illustrating the present invention, and unlimited
The scope of the present invention processed.
Embodiment 1
One kind treats gingivitis and canker sore Chinese medical collutory, is made up of the component of following parts by weight：
5 grams of Chinese anise, 10 grams of elscholtiza, 25 grams of peppermint, 5 grams of honeysuckle, 15 grams of lophatherum gracile, 10 grams of catechu, 3 grams of radix glycyrrhizae, water
3000 milliliters.
A kind of preparation method for treating gingivitis and canker sore Chinese medical collutory, comprises the following steps：
（1）3 grams of 5 grams of extracting honeysuckle, 15 grams of lophatherum gracile, 10 grams of catechu, radix glycyrrhizae mixing, add 3000 milliliters of water, after being boiled by fire
It is cooked by medium heat, maintains 100 DEG C of temperature, decocts half an hour；
（2）5 grams of Chinese anise, 10 grams of elscholtiza, 25 grams of peppermint are added, continues to boil to remaining 1600 milliliters of liquid；
（3）Take the Chinese medicinal liquor to add 50 degree of 400 milliliters of rice wine after being cooled to 25 DEG C, be distributed into 200 milliliters one bottle, produce to contain and gargle
Liquid.
Embodiment 2
One kind treats gingivitis and canker sore Chinese medical collutory, is made up of the component of following parts by weight：
5 grams of Chinese anise, 15 grams of elscholtiza, 30 grams of peppermint, 10 grams of honeysuckle, 20 grams of lophatherum gracile, 15 grams of catechu, 5 grams of radix glycyrrhizae, water
3000 milliliters.
A kind of preparation method for treating gingivitis and canker sore Chinese medical collutory, comprises the following steps：
（1）5 grams of 10 grams of extracting honeysuckle, 20 grams of lophatherum gracile, 15 grams of catechu, radix glycyrrhizae mixing, add 3000 milliliters of water, after being boiled by fire
It is cooked by medium heat, maintains 100 DEG C of temperature, decocts half an hour；
（2）5 grams of Chinese anise, 15 grams of elscholtiza, 30 grams of peppermint are added, continues to boil to remaining 1600 milliliters of liquid；
（3）Take the Chinese medicinal liquor to add 50 degree of 400 milliliters of rice wine after being cooled to 25 DEG C, be distributed into 200 milliliters one bottle, produce to contain and gargle
Liquid.
Embodiment 3
One kind treats gingivitis and canker sore Chinese medical collutory, is made up of the component of following parts by weight：
10 grams of Chinese anise, 20 grams of elscholtiza, 35 grams of peppermint, 15 grams of honeysuckle, 25 grams of lophatherum gracile, 20 grams of catechu, 8 grams of radix glycyrrhizae, water
3000 milliliters.
A kind of preparation method for treating gingivitis and canker sore Chinese medical collutory, comprises the following steps：
（1）8 grams of 15 grams of extracting honeysuckle, 25 grams of lophatherum gracile, 20 grams of catechu, radix glycyrrhizae mixing, add 3000 milliliters of water, after being boiled by fire
It is cooked by medium heat, maintains 100 DEG C of temperature, decocts half an hour；
（2）10 grams of Chinese anise, 20 grams of elscholtiza, 35 grams of peppermint are added, continues to boil to remaining 1600 milliliters of liquid；
（3）Take the Chinese medicinal liquor to add 50 degree of 400 milliliters of rice wine after being cooled to 25 DEG C, be distributed into 200 milliliters one bottle, produce to contain and gargle
Liquid.
Embodiment 4
One kind treats gingivitis and canker sore Chinese medical collutory, is made up of the component of following parts by weight：
8 grams of Chinese anise, 13 grams of elscholtiza, 35 grams of peppermint, 5 grams of honeysuckle, 20 grams of lophatherum gracile, 15 grams of catechu, 5 grams of radix glycyrrhizae, water
3000 milliliters.
A kind of preparation method for treating gingivitis and canker sore Chinese medical collutory, comprises the following steps：
（1）5 grams of 5 grams of extracting honeysuckle, 20 grams of lophatherum gracile, 15 grams of catechu, radix glycyrrhizae mixing, add 3000 milliliters of water, after being boiled by fire
It is cooked by medium heat, maintains 100 DEG C of temperature, decocts half an hour；
（2）8 grams of Chinese anise, 13 grams of elscholtiza, 35 grams of peppermint are added, continues to boil to remaining 1600 milliliters of liquid；
（3）Take the Chinese medicinal liquor to add 400 milliliters of rice wine 50 degree after being cooled to 25 DEG C, be distributed into 200 milliliters one bottle, produce to contain and gargle
Liquid.
Embodiment 5
One kind treats gingivitis and canker sore Chinese medical collutory, is made up of the component of following parts by weight：
6 grams of Chinese anise, 15 grams of elscholtiza, 25 grams of peppermint, 15 grams of honeysuckle, 22 grams of lophatherum gracile, 15 grams of catechu, 3 grams of radix glycyrrhizae, water
3000 milliliters.
A kind of preparation method for treating gingivitis and canker sore Chinese medical collutory, comprises the following steps：
（1）3 grams of 15 grams of extracting honeysuckle, 22 grams of lophatherum gracile, 15 grams of catechu, radix glycyrrhizae mixing, add 3000 milliliters of water, after being boiled by fire
It is cooked by medium heat, maintains 100 DEG C of temperature, decocts half an hour；
（2）6 grams of Chinese anise, 15 grams of elscholtiza, 25 grams of peppermint are added, continues to boil to remaining 1600 milliliters of liquid；
（3）Take the Chinese medicinal liquor to add 50 degree of 400 milliliters of rice wine after being cooled to 25 DEG C, be distributed into 200 milliliters one bottle, produce to contain and gargle
Liquid.
Claims (2)
1. one kind treats gingivitis and canker sore Chinese medical collutory, it is characterised in that：It is made up of the component of following parts by weight：
Chinese anise 5-10 parts, elscholtiza 10-20 parts, peppermint 25-35 parts, honeysuckle 5-15 parts, lophatherum gracile 15-25 parts, catechu 10-
20 parts, radix glycyrrhizae 3-8 parts, 3000 parts of water.
2. a kind of method for the treatment of gingivitis prepared described in claim 1 and canker sore Chinese medical collutory, it is characterised in that：
Comprise the following steps：
（1）Extracting honeysuckle 5-15 parts, lophatherum gracile 15-25 parts, catechu 10-20 parts, the mixing of radix glycyrrhizae 3-8 parts, add 3000 parts of water, with big
Fire is cooked by medium heat after boiling, and maintains 100 DEG C of temperature, decocts half an hour；
（2）Chinese anise 5-10 parts, elscholtiza 10-20 parts, peppermint 25-35 parts are added, continues to boil to remaining 1600 parts of liquid；
（3）Take the Chinese medicinal liquor to add 50 degree of 400 milliliters of rice wine after being cooled to 25 DEG C, be distributed into 200 milliliters one bottle, produce to contain and gargle
Liquid.
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| CN110384725A (en) * | 2019-09-18 | 2019-10-29 | 江西中医药大学 | A kind of preparation of Chinese traditional medicine composition and its activity extract for adjusting oral cavity flora |
| CN117482198A (en) * | 2018-12-24 | 2024-02-02 | 东莞御叶香媛生物科技有限公司 | A kind of Wanxiang fruit environmentally friendly enzyme that inhibits gum bleeding, its preparation method and its application |
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| CN104721556A (en) * | 2013-12-20 | 2015-06-24 | 陕西康乐中医药养生研究院 | Traditional Chinese medicine used for treating oral ulcer |
| CN105853640A (en) * | 2015-01-22 | 2016-08-17 | 天津法莫西医药科技有限公司 | Traditional Chinese medicine pulvis for treating oral ulcer and preparation method thereof |
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| CN104721556A (en) * | 2013-12-20 | 2015-06-24 | 陕西康乐中医药养生研究院 | Traditional Chinese medicine used for treating oral ulcer |
| CN104383350A (en) * | 2014-12-11 | 2015-03-04 | 福建农林大学 | Traditional Chinese medicine compound gargling effervescent tablets and preparation method thereof |
| CN105853640A (en) * | 2015-01-22 | 2016-08-17 | 天津法莫西医药科技有限公司 | Traditional Chinese medicine pulvis for treating oral ulcer and preparation method thereof |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117482198A (en) * | 2018-12-24 | 2024-02-02 | 东莞御叶香媛生物科技有限公司 | A kind of Wanxiang fruit environmentally friendly enzyme that inhibits gum bleeding, its preparation method and its application |
| CN110384725A (en) * | 2019-09-18 | 2019-10-29 | 江西中医药大学 | A kind of preparation of Chinese traditional medicine composition and its activity extract for adjusting oral cavity flora |
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Application publication date: 20180202 |