CN105168821A - Cough-relieving traditional Chinese medicine composition and preparation method thereof - Google Patents
Cough-relieving traditional Chinese medicine composition and preparation method thereof Download PDFInfo
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- CN105168821A CN105168821A CN201510532203.XA CN201510532203A CN105168821A CN 105168821 A CN105168821 A CN 105168821A CN 201510532203 A CN201510532203 A CN 201510532203A CN 105168821 A CN105168821 A CN 105168821A
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Abstract
The invention discloses a cough-relieving traditional Chinese medicine composition and a preparation method thereof. The medicine comprises cucumber stem, pond-bottom lichee leaf, carp's gallbladder, human nail, radix ranunculi ternati, crocodile blood, pond dragon, brackish-water crab, garlic, RADIX PUERARIAE, orange peel, rhizoma pinelliae, sterculia nobilis Smith and macrosolen cochinchinensis (Lour.)Van Tiegh. The preparation method comprises: step A, weighing the ingredients according to the weight fractions in a formula; step B, getting human nail and grinding, drying brackish-water crab and rhizoma pinelliae in the sun, putting human nail, brackish-water crab and rhizoma pinelliae into a pot and frying together with stirring under the condition of big fire for 2-5 min; step C, adding the other compositions except for carp's gallbladder into the pot in the step B, adding water with the amount being 10-20 times and boiling for 20-120 min; and step D, adding carp's gallbladder bile into the pot of the step C, so as to obtain the finished product. The invention aims at overcoming disadvantages of the prior art and providing the cough-relieving composition which is reasonable in matching ratio and fast in curative effect and used for treating cold and cough. The invention also aims at providing the method for preparing the above composition for treating cold and cough.
Description
Technical field
The present invention relates to a kind of cough relief traditional Chinese medicine compositions, the invention still further relates to a kind of method preparing above-mentioned cough relief traditional Chinese medicine compositions.
Background technology
Cold cough is a kind of commonly encountered diseases and frequently-occurring disease, coughs frequently unhealthful, and especially child and old man, coughs larger to its health effect.Not only endanger own health, also affect surrounding population.At present, the medicine having many treatment coughs of market medicine store merchandising, as: JIZHI TANGJIANG, MILIAN CHUANBEI PIPA GAO, cough spirit, Succus Fel Serpentis et Bulbus Fritillariae Cirrhosae etc., but patient takes rear reaction, and curative effect is not very good.
Existing cough relief traditional Chinese medicine compositions takes effect slowly, can not meet the demand of patient, so existing cough relief traditional Chinese medicine compositions needs to be further improved.
Summary of the invention
The object of the invention is in order to overcome weak point of the prior art, to provide a kind of reasonable mixture ratio, the cough relief traditional Chinese medicine compositions that curative effect is fast.
Another object of the present invention is to provide a kind of method preparing above-mentioned cough relief traditional Chinese medicine compositions.
In order to achieve the above object, the present invention adopts following scheme:
A kind of cough relief traditional Chinese medicine compositions, is characterized in that comprising following component by weight:
A kind of cough relief traditional Chinese medicine compositions as above, is characterized in that also comprising following component by weight:
Herba Gerberae Piloselloidis 1-22 heronsbill 5-35
Caulis menispermi 0.1-3 Cyrtomium fortunei J. Sm. 2-42.
A kind of cough relief traditional Chinese medicine compositions as above, is characterized in that also comprising following component by weight:
Herba Asparagi Setacei 6-35 Rhizoma Helminthostachydis Zeylanicae 3-19
Cortex Syringae 1-26 Radix Achyranthis 3-13.
A kind of cough relief traditional Chinese medicine compositions as above, is characterized in that also comprising following component by weight:
A kind of method preparing cough relief traditional Chinese medicine compositions described above of the present invention, is characterized in that comprising the following steps:
A, take each component by the weight portion in prescription;
B, get Concha and grind into powder, Sesarmae dehaani, the Rhizoma Pinelliae are dried, enter together a pot big fire stir-fry 2-5 minute for subsequent use;
C, in the pot in step B, add other component except Fel Cyprinus carpio, add 10-20 times of soak by water 20-120 minute;
D, in step C, add the bile of Fel Cyprinus carpio.
In sum, the present invention relative to its beneficial effect of prior art is:
Reasonable mixture ratio of the present invention, Fang Zhong:
1, Caulis Cucumidis sativiv: spasmolytic of eliminating the phlegm.
2, Folium Litchi at the bottom of the pool: property is flat, lightly seasoned, heat-clearing and toxic substances removing;
3, Fel Cyprinus carpio: bitter in the mouth, cold in nature, clearing away heat to improve acuity of vision, nebula removing is subsided a swelling, sore-throat relieving.
4, Concha: sweet in the mouth, salty, property is put down.For epistaxis, hematuria, laryngopharynx swelling and pain, dysuria, the raw cataracta of order, otitis media.
5, Radix Ranunculi Ternati: dissipating phlegm and resolving masses, removing toxic substances and promoting subsidence of swelling, treatment Drug resistant pulmonary tubeculosis.
6, crocodile blood: there is the effects such as antiinflammatory, heat-clearing and toxic substances removing, treating tumor;
7, Herba Jussiaeae Repentis: there is heat clearing away, diuresis, effect of removing toxic substances.Be usually used in cold, fever, cough caused by dryness-heat, high hot excessive thirst, drench pain, edema, pharyngalgia, larynx swells, aphtha, acute toothache, and carbuncle sore furuncle swells, burn and scald, and traumatic injury wound is swollen, poisonous snake, lyssodexis.
8, Sesarmae dehaani: the effect with detoxicating, relieving inflammation, effective especially to treatment laryngopharynx swelling and pain, come from " China's book on Chinese herbal medicine ";
9, Bulbus Allii: removing toxic substances parasite killing, reducing swelling and alleviating pain, antidiarrheal dysentery relieving, controls lung, anthelmintic, also has warming the spleen warming the stomach in addition.Control swollen ulcer drug, white bald tinea skin ulcer, dysentery is had loose bowels, pulmonary tuberculosis pertussis, ascarid pinworm, eating accumulation, coldness and pain in the epigastrium, edema distension.
10, Radix Puerariae: sweet in the mouth, pungent, cool in nature.Expelling pathogenic factors from muscles for reducing heat, rash, promoting the production of body fluid to quench thirst, yang invigorating antidiarrheal.
11, Pericarpium citri sinensis: fast diarrhea due to disorder of QI every, eliminating phlegm and lowering adverse QI, the stomach function regulating that helps digestion, neutralize the effect of alcoholic drinks, kill fish Eriocheir sinensis poison.The main chest and diaphragm stagnation of QI, cough with copious phlegm, diet do not disappear, nausea and vomiting, drunk.
12, the Rhizoma Pinelliae: drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.For abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm is had a headache, vomiting regurgitation, and breast gastral cavity painful abdominal mass is vexed, globus hystericus; Raw with external treatment carbuncle sucutaneous nodule.
13, sterculia nobilis: sweet, temperature.Yao Kecheng " food book on Chinese herbal medicine ": " control the infested and children's of internal organs and eat earth, stomachache, addiction block is long-pending hard.Nourishing the liver gallbladder, improving eyesight removing nebula, suppressing cough and abating fever, separates sharp ailment said due to cold or exposure, and disappear tired pathogenic fire reducing.”
14, Arillus Longan is parasitic: wind-damp dispelling; Invigorating the liver and kidney; Promoting blood circulation and stopping pain; Cough-relieving; Dysentery relieving.Main air pain of dampness syndrome; Soreness of waist and knee joint; Have a dizzy spell; Alopecia; Traumatic injury; Swelling and pain of hemorrhoid; Cough; Hemoptysis; Dysentery.
15, Herba Gerberae Piloselloidis: cure mainly lung qi dispersing, cough-relieving, diaphoresis, diuretic, circulation of qi promoting, invigorates blood circulation.Control the cough due to common cold, asthma, edema, distension, urinary obstruction, food stagnation of child, married woman's amenorrhea, traumatic injury, carbuncle, furuncle, multiple abscess.
16, heronsbill: tool heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, the function such as anticancer.
17, Caulis menispermi: blood pressure lowering, antipyretic, analgesia.
18, Cyrtomium fortunei J. Sm.: heat-clearing and toxic substances removing, cooling blood for calming endogenous wind, loose expectorant hemostasis, cures cold.
19, Herba Asparagi Setacei: nourishing the lung to arrest cough, reducing heat in the blood and treating stranguria, diuresis is detoxified..Cure mainly pulmonary tuberculosis cough, acute bronchitis, amebic dysentery, lung-dryness syndrome due to deficiency of YIN; Cough; Spitting of blood; Dribbling urination.
20, Rhizoma Helminthostachydis Zeylanicae: removing heat-phlegm, antidotes against snake bite.For pharyngitis, tonsillitis, cough, asthma; Venom is controlled in external.
21, Cortex Syringae: eliminate the phlegm and cough-relieving.
22, Radix Achyranthis: have heat-clearing and toxic substances removing, diuresis effect, cures mainly cold, fever, tonsillitis, diphtheria, mumps, urinary system calculus, the diseases such as oedema due to nephritis.
23, Herba nepenthis: clearing away lung-heat and moistening for dryness, row water, removing toxic substances.Control xeropulmonary cough, pertussis, jaundice, stomachache, dysentery, edema, carbuncle, insect bite is hindered.
24, Herba Buddlejae Lindleyanae: cure mainly and dispel the wind, parasite killing, invigorates blood circulation.Control influenza, cough, asthma etc.
25, Radix Zanthoxyli Avicennae: control laryngopharynx swelling and pain, general edema with yellowish skin, malaria, rheumatic ostalgia, traumatic injury is dampened.
26, Herba Iridis japonicae: heat-clearing and toxic substances removing, dissipating blood stasis, cough-relieving, diuresis.For cough, infantile scrofula, innominate toxic swelling.
27, Semen Benincasae: lung moistening, reduces phlegm, eliminating carbuncle, diuretic.Control phlegm-heat cough, lung abscess, acute appendicitis, gonorrhea, edema, beriberi, hemorrhoid, nasal surface wine Zha.
28, Fel Anseris domestica: heat-clearing and toxic substances removing, controls hemorrhoid, cough.
29, floral disc of sunflower: removing heat-phlegm, the merit of cooling blood for hemostasis, to headache, dizziness etc. effectively.
Detailed description of the invention
Below in conjunction with detailed description of the invention, the invention will be further described:
Embodiment 1
A kind of cough relief traditional Chinese medicine compositions, comprises following component by weight:
Embodiment 2
A kind of cough relief traditional Chinese medicine compositions, comprises following component by weight:
Embodiment 3
A kind of cough relief traditional Chinese medicine compositions, comprises following component by weight:
Embodiment 4
A kind of cough relief traditional Chinese medicine compositions, comprises following component by weight:
Embodiment 5
A kind of cough relief traditional Chinese medicine compositions, comprises following component by weight:
Embodiment 6
A kind of cough relief traditional Chinese medicine compositions, comprises following component by weight:
Embodiment 7
A kind of cough relief traditional Chinese medicine compositions, comprises following component by weight:
Embodiment 8
A kind of cough relief traditional Chinese medicine compositions, comprises following component by weight:
Embodiment 9
A kind of cough relief traditional Chinese medicine compositions, comprises following component by weight:
Embodiment 10
A kind of cough relief traditional Chinese medicine compositions, comprises following component by weight:
Embodiment 11
A kind of cough relief traditional Chinese medicine compositions, comprises following component by weight:
Embodiment 12
A kind of cough relief traditional Chinese medicine compositions, comprises following component by weight:
Embodiment 13
A kind of cough relief traditional Chinese medicine compositions, comprises following component by weight:
Embodiment 14
A kind of cough relief traditional Chinese medicine compositions, comprises following component by weight:
Embodiment 15
A kind of cough relief traditional Chinese medicine compositions, comprises following component by weight:
Embodiment 16
A kind of cough relief traditional Chinese medicine compositions, comprises following component by weight:
Embodiment 17
A kind of cough relief traditional Chinese medicine compositions, comprises following component by weight:
Embodiment 18
A kind of cough relief traditional Chinese medicine compositions, comprises following component by weight:
Embodiment 19
A kind of cough relief traditional Chinese medicine compositions, comprises following component by weight:
Embodiment 20
A kind of cough relief traditional Chinese medicine compositions, comprises following component by weight:
Medicine in embodiment of the present invention 1-20 can be prepared by the following method:
A, take each component by the weight portion in prescription;
B, get Concha and grind into powder, Sesarmae dehaani, the Rhizoma Pinelliae are dried, enter together a pot big fire stir-fry 2-5 minute for subsequent use;
C, in the pot in step B, add other component except Fel Cyprinus carpio, add 10-20 times of soak by water 20-120 minute;
D, in step C, add the bile of Fel Cyprinus carpio.
In order to show the therapeutic effect of the present invention in treatment cold cough, invention has been following animal experiment and clinical trial:
Get body weight 18-22g mice 100, be divided into 4 groups at random, blank group gives gavage normal saline, and the other gavage of test component gives medicine 0.5g/kg, 1.0g/kg of the present invention, 2.0g/kg; Positive control gives Folium Eriobotryae cough-relieving electuary 2.0g/kg, and gavage volume is 2ml/100g successive administration 5 days.After last administration 30 minutes, mice is put in closed glass case, quantitatively spray into strong aqua ammonia aerosol to lure and cough, record in mouse cough incubation period and 3 minutes number of times of coughing, result: the average cough latent period of tested combination positive drug control group all extend more than 25 seconds, average cough number of times obviously reduces, and shows that this product has obvious antitussive effect:
Expectorant test:
The impact phenol red on mice trachea excretion: get body weight 18-22g mice, the other gavage of test component gives medicine 0.5g/kg, 1.0g/kg of the present invention, 2.0g/kg; Positive control gives Folium Eriobotryae cough-relieving electuary 2.0g/kg, and blank group gives gavage normal saline, successive administration 5 days.After last administration 30 minutes, the phenol red normal saline solution of lumbar injection 0.25%.Put to death mice after 30 minutes, rinse pulmonary branches trachea and collect irrigating solution, measure OD value, result shows that medicine of the present invention significantly can increase the phenol red amount of mice trachea excretion, has obvious phlegm-dispelling functions.
Clinical trial:
The cough after flu, pharyngolaryngitis is selected, the Patients with 300 Cases of the symptoms such as aphonia, xerostomia pharyngalgia, wherein course of disease 1-5 days 126 examples, 5-10 days 104 examples, more than 10 days 70 examples from clinic case.
Take medicine decoction of the present invention, every twice-daily.Cough in 1-3 days disappears substantially, the transference cures such as pharyngalgia, effective percentage 100%.
Impact on Hair of Rat tubule expectoration amount: rat is divided into 4 groups, after the anesthesia of lumbar injection pentobarbital sodium, cuts cervical region, is separated trachea, insert glass capillary, record the amount of sucking-off expectorant in 2 hours.Be put to the test and organize gavage respectively and give medicine 0.5g/kg, 1.0g/kg of the present invention, 2.0g/kg; Matched group gives gavage normal saline, and gavage volume is 2ml/100g, continues observation 2 hours amounts of expectoration, record administration forward backward averaging secretory volume per hour.Result shows that tested group of high and low dose group all can increase rat trachea expectoration amount, has obvious phlegm-dispelling functions.
More than show and describe ultimate principle of the present invention and principal character and advantage of the present invention.The technical staff of the industry should understand; the present invention is not restricted to the described embodiments; what describe in above-described embodiment and description just illustrates principle of the present invention; without departing from the spirit and scope of the present invention; the present invention also has various changes and modifications, and these changes and improvements all fall in the claimed scope of the invention.Application claims protection domain is defined by appending claims and equivalent thereof.
Claims (5)
1. a cough relief traditional Chinese medicine compositions, is characterized in that comprising following component by weight:
2. a kind of cough relief traditional Chinese medicine compositions according to claim 1, is characterized in that also comprising following component by weight:
3. a kind of cough relief traditional Chinese medicine compositions according to claim 1 and 2, is characterized in that also comprising following component by weight:
4. a kind of cough relief traditional Chinese medicine compositions according to claim 3, is characterized in that also comprising following component by weight:
5. prepare a method for cough relief traditional Chinese medicine compositions as claimed in claim 1 or 2, it is characterized in that comprising the following steps:
A, take each component by the weight portion in prescription;
B, get Concha and grind into powder, Sesarmae dehaani, the Rhizoma Pinelliae are dried, enter together a pot big fire stir-fry 2 ?5 minutes for subsequent use;
C, in the pot in step B, add other component except Fel Cyprinus carpio, add 10 ?20 times of soak by water 20 ?120 minutes;
D, in step C, add the bile of Fel Cyprinus carpio.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105031365A (en) * | 2015-08-26 | 2015-11-11 | 唐媚英 | Traditional Chinese medicine for preventing and treating cold and cough and preparation method thereof |
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| CN104324217A (en) * | 2014-11-11 | 2015-02-04 | 覃永红 | Oral liquid for reducing phlegm and relieving cough |
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| CN102698216A (en) * | 2012-04-21 | 2012-10-03 | 王伟良 | Formula and preparation method of medicament for preventing and treating cold and cough |
| CN104324217A (en) * | 2014-11-11 | 2015-02-04 | 覃永红 | Oral liquid for reducing phlegm and relieving cough |
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| 本书专家组: "《中医助理医师应试指导》", 31 January 2015, 中国协和医科大学出版社 * |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105031365A (en) * | 2015-08-26 | 2015-11-11 | 唐媚英 | Traditional Chinese medicine for preventing and treating cold and cough and preparation method thereof |
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Application publication date: 20151223 |