CN103656320B - For preventing and treating the oral administered compound Chinese medicine preparation of birds anemofrigid cold, influenza - Google Patents
For preventing and treating the oral administered compound Chinese medicine preparation of birds anemofrigid cold, influenza Download PDFInfo
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Abstract
The invention discloses a kind of oral administered compound Chinese medicine preparation for preventing and treating birds anemofrigid cold, influenza; this Chinese medicine preparation is made up of the raw material mix homogeneously of following parts by weight: Herba Schizonepetae 120 ~ 200 parts; Cornu Bovis seu Bubali silk 50 ~ 80 parts, taurine 15 ~ 35 parts, shikimic acid 20 ~ 60 parts, 80 ~ 150 parts, Gypsum Fibrosum, Borneolum Syntheticum 1 ~ 3 part, Herba Menthae 80 ~ 150 parts, Herba Violae 80 ~ 150 parts, Rhizoma Phragmitis 30 ~ 80 parts, Radix Isatidis 10 ~ 50 parts.The present invention adopts Chinese medicine extract, have the Chinese medicinal powder of unique effects is re-dubbed compound preparation, there is antiinflammatory, sterilization, antiviral, heart tonifying, antitussive, antiallergic action, promote poultry anti pathologic immunity power, repair impaired mucosa, effectively control the effects such as secondary infection, have efficient therapeutical effect to avian influenza, influenza.Formula rationally, simple, the Be very effective of science, preparation, to be widely used, can be used as the choice drug of prevention and therapy avian influenza, influenza.
Description
Technical field
The present invention relates to a kind of fowl medicine, particularly relating to a kind of oral administered compound Chinese powder medicine for preventing and treating birds anemofrigid cold, influenza.
Background technology
Aquaculture is the pillar industry in modern agriculture, and the sustainable and stable development of aquaculture is for promoting the development of modern agriculture and the material support providing strong of uplifting the people's living standard.But current China's cultivation level backwardness relatively, some small-sized raisers lack management system and the technological means of science, drive by interests, adopt inappropriate method for breeding and means to produce inferior even poisonous animal products.In feeding process, abuse antimicrobial drug, cause on the one hand that medicine is residual to exceed standard, the health of serious harm people, facilitates the generation of " superbacteria " on the other hand.In several past years, the event such as " clenbuterol hydrochloride ", tripolycyanamide in rapid succession, causes the healthy of people and consumer psychology and has a strong impact on.Therefore, science healthy aquaculture and standardization medication are current cultivation industry problems in the urgent need to address.Chinese herbal medicine and preparation thereof have nontoxic, noresidue, not easily produce the advantages such as drug resistance, and China's Chinese herbal medicine resource enriches, and show academic significance more and more important in herbal control, practical value and unlimited prospect.And anemofrigid cold, influenza (comprising influenza) are one of major diseases of harm aquaculture always, therefore, a kind of scientific formula being provided, without drug resistance, the Chinese traditional compound medicine for preventing and treating birds anemofrigid cold, influenza evident in efficacy, namely becoming one of this those skilled in the art's problem demanding prompt solution.
In the achievement that China's application herbal control livestock and poultry is with a long history and abundant.Over nearly more than 10 years, the development of intensive culture industry, numerous veterinarys scientific worker and cultivation worker are in scientific experiments and production practices, use theoretical system and the application form of Chinese medicine uniqueness, in conjunction with the feature such as physiology, pathology of animal, probe boldly, constantly bring forth new ideas, develop Chinese herbal medicine resource, in diseases prevention and treatment, obtain important breakthrough and happiness man-based development.Application Chinese herbal medicine not only can be treated, and can prevent; Not only can prevent and treat common disease, can also infectious disease be prevented and treated, even in the control of deadly infectious disease, also obtain compellent effect; Also from individual treatment to mass prevention and mass treatment, adapt to the needs of intensive farm; Particularly Chinese herbal medicine nonspecific immunity is prevented and treated to exploration and the breakthrough of aspect, not only prove that Chinese herbal medicine has science and has actuality again, and will huge science and technology be caused to change by medical domain at home and abroad.
The application of Chinese herbal medicine in aquaculture: the preparation be made up of Chinese herbal medicine is a lot, has a wide range of applications in livestock breeding industry.Its Main Function has immunostimulant, weightening finish of fattening, anti-bacteria and anti-virus, anthelmintic, growth-promoting are grown and lactogenic, seasoning, painted, fresh-keeping etc.Various application features now with regard to Chinese herbal and crude drugs preparations are simply introduced.
Chinese medicine immunity enhancer: the composition that Chinese herbal medicine strengthens immunity mainly contains polysaccharide, organic acid, alkaloid, glycoside and volatile oil.The mechanism of its effect is that 1. Chinese herbal medicine can promote the growth of Immune Organs of Body; 2. Chinese herbal medicine is to the immunologic enhancement of leukocyte and monocytes/macrophages system; 3. Chinese herbal medicine is to the facilitation of natural killer cell; 4. Chinese herbal medicine is to the facilitation of cytokine; 5. Chinese herbal medicine is to the facilitation of cellular immunization; 6. Chinese herbal medicine is to the facilitation of humoral immunization; 7. the two-way immunoregulation effect of Chinese herbal medicine, much Chinese medicine or its active ingredient are dual regulation to body's immunity, and one is the two-way immunoregulation effect of dose dependent, and one is the two-way immunoregulation effect of activity-dependent.The two-way immunoregulation effect of dose dependent shows as low dose (or low concentration) and promotes body's immunity, and heavy dose of (or high concentration) suppresses body's immunity; And the two-way immunoregulation effect of activity-dependent can make (hyperfunction or low) immune state of body machine disorder recover normal.
Chinese herbal antibacterial agent and anthelmintic: have some fine antibacterial and anthelmintics in the middle of Chinese herbal medicine, as the Radix Dichroae, the Radix Pulsatillae etc. of Chinese medicine anthelmintic Semen Arecae, Fructus Quisqualis, Herba Buddlejae Lindleyanae and anticoccidial.And most Chinese herbal medicine is for major function with eliminating evil double righting, these Chinese herbal antibacterial anti-infective action principles mainly comprise virulence (aggressivity and toxin) to microorganism or direct killing power, but play and strengthen organ-tissue antibacterial functions, strengthen reticuloendothelial system phagocytic function and inducement interferon and the antianaphylactic effect of other antiinflammatory to body tissue.In view of these specific functions of Chinese herbal medicine, be highly suitable for the diseases prevention and treatment of ecological cultivation farm, particularly for the plant (as foster eel field, prawn field, outlet barren sow field) producing outlet animal product, Chinese herbal medicine has more played absolute irreplaceable advantage.
Chinese herbal medicine is fattened weighting agent: adopt Chinese herbal medicine as the weightening finish preparation of fattening of poultry, long history is had in China, particularly after eighties of last century eighties, start again the upsurge of Chinese herbal feed additive, nowadays this class additive almost relates to all poultry and aquatic animal, and style is a lot of.On current Chinese herbal feed additive market, the Chinese herbal feed additive most species of pig, its function has dyspepsia and intestinal stasis relieving, regulating qi-flowing for strengthening spleen, expelling intestinal worms and removing food stagnancy, evil removing heat clearing away etc.
Growth-promoting grows the hormonelike Chinese herbal and crude drugs preparations with lactogenic: growth-promoting grow mainly to refer to the hormonelike Chinese herbal and crude drugs preparations of lactogenic those can QI and blood regulating, tonify Qi of the kidney, spermatogenesis ovulation, vigorous mammary gland, to promote the sexual maturity and the Chinese herbal and crude drugs preparations of gonadal hormone sample.Motherland's theory of medicine is thought, the reproduction of animal body is body equilibrium between yin and yang, internal organs coordination, essence and blood and suitable embodiment.Reproduction and each internal organs of body closely related, and to be led by kidney because kidney hides congenital essence, also relevant to liver spleen because blood stored in the liver, the spleen being the foundation of acquired constitution, and the spleen governs the blood.So this kind of Chinese herbal medicine focuses on the kidney invigorating and essence nourishing blood, need animal body integrated regulation, determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs.The Chinese herbal medicine of compensate qi and blood has the Radix Astragali, Radix Codonopsis, Radix Angelicae Sinensis, slender acanthopanax, Radix Glycyrrhizae etc.; The Chinese herbal medicine of the kidney invigorating and essence nourishing has the Cortex Eucommiae, Radix Morindae Officinalis, Herba Epimedii, Fructus Psoraleae, Semen Cuscutae etc.; The Chinese herbal medicine of induced ovulation of promoting the sexual maturity has Herba Epimedii, Actinolitum, Semen Trigonellae, Rhizoma Curculiginis and Flos lupuli (Flos Humuli Lupuli) etc.; The Chinese herbal medicine of lactogenic has Semen Vaccariae, Squama Manis, Radix Rhapontici, Sargassum etc.
Anti-stress Chinese herbal and crude drugs preparations: animal growth stress be caused slow, system disorder, fertility performance declines, and product quality is inferior, and body's immunity even can be caused to weaken and various disease occurs.The stressor sorted generalization destroying animal body physiology and psychological stabilization and automatic regulation function thereof is six climate exopathogens (wind, cold, summer-heat, wet, dry, fiery) and seven emotions (like, anger, melancholy, think of, compassion, fear, shy) by motherland's medical science.And in aquaculture, endangering maximum stressor to body is heat stress.And the animal the most responsive to heat stress performance is milch cow and poultry.In the feed additive of anti-heat stress, at present mainly based on the alleviant of sodium bicarbonate and vitamin C, in addition, also have antipyretic tranquilizer, electrolyte, antibiotics and part trace element etc.Though these Western medicine buffer agent anti-heat stress have certain effect, but the use that chemical drugs is long-term, easily toxicity, side effect is produced to milch cow and laying hen, and chemical drugs remaining in Lac Bovis seu Bubali and egg, have a strong impact on breast, the quality of egg and the healthy of consumer, adopt the experimental study of the anti-heat stress of cow in summer of Chinese herbal feed additive all to obtain good effect over the years.Make a general survey of anti-heat stress Chinese herbal medicine additive, major part is the Chinese herbal medicine of clearing away summer-heat, tonifying QI to produce body fluid and strengthening the spleen and nourishing the stomach, as Gypsum Fibrosum, Folium Nelumbinis, Radix Isatidis, Rhizoma Phragmitis, the Radix Paeoniae Alba and so on, action principle aspect, first should clearing away summer-heat, reuse the cooling of Gypsum Fibrosum, Folium Nelumbinis and so on expelling summer-heat, secondly summer-heat is stranded spleen, the most easily affect milch cow and laying hen appetite, cause milk yield and egg production to decline.So adopt the Chinese herbal medicine of strengthening the spleen and nourishing the stomach to promote appetite, strengthen digestion merit, make milch cow and laying hen keep vigorous appetite, ensure that normal milk production and egg production.
Chinese herbal medicine also can be used as flavoring agent, coloring agent, preserving agent etc.In a word, utilize the characteristics and advantages of Chinese herbal medicine, widely popularize in aquaculture and apply, solve the ubiquitous drug residue of cultured product and problem of poor quality, by the effect of playing very well in green animal husbandry.
Summary of the invention
Object of the present invention is intended to overcome above-mentioned weak point, provides a kind of green, efficient, noresidue, has no drug resistance, the Chinese traditional compound medicine for preventing and treating birds anemofrigid cold, influenza for the treatment of both the principal and secondary aspects of a disease.
The technical scheme that the present invention solves its technical problem is: a kind of oral administered compound Chinese medicine preparation for preventing and treating birds anemofrigid cold, influenza; this Chinese medicine preparation is made up of the raw material mix homogeneously of following parts by weight: Herba Schizonepetae 120 ~ 200 parts; Cornu Bovis seu Bubali silk 50 ~ 80 parts, taurine 15 ~ 35 parts, shikimic acid 20 ~ 60 parts, 80 ~ 150 parts, Gypsum Fibrosum, Borneolum Syntheticum 1 ~ 3 part, Herba Menthae 80 ~ 150 parts, Herba Violae 80 ~ 150 parts, Rhizoma Phragmitis 30 ~ 80 parts, Radix Isatidis 10 ~ 50 parts.
Described oral administered compound Chinese medicine preparation is made up of the raw material mix homogeneously of following parts by weight: Herba Schizonepetae 140 ~ 180 parts; Cornu Bovis seu Bubali silk 60 ~ 70 parts, taurine 20 ~ 25 parts, shikimic acid 30 ~ 40 parts, 90 ~ 130 parts, Gypsum Fibrosum, Borneolum Syntheticum 1.5 ~ 2.5 parts, Herba Menthae 100 ~ 130 parts, Herba Violae 110 ~ 120 parts, Rhizoma Phragmitis 40 ~ 60 parts, Radix Isatidis 15 ~ 35 parts.
Described oral administered compound Chinese medicine preparation is made up of the raw material mix homogeneously of following parts by weight: Herba Schizonepetae 140 ~ 180 parts; Cornu Bovis seu Bubali silk 60 ~ 70 parts, taurine 20 ~ 30 parts, shikimic acid 30 ~ 50 parts, 90 ~ 130 parts, Gypsum Fibrosum, Borneolum Syntheticum 1.5 ~ 2.5 parts, Herba Menthae 100 ~ 130 parts, Herba Violae 90 ~ 130 parts, Rhizoma Phragmitis 40 ~ 70 parts, Radix Isatidis 15 ~ 40 parts.
Described taurine is the taurine extracted in natural biological product.
Described shikimic acid is a kind of monomeric compound extracted from Chinese medicine Fructus Anisi Stellati.
The pharmacological property of the various medicine of the present invention is analyzed as follows:
Herba Schizonepetae: the medicinal efficacy that Herba Schizonepetae has dispeling the wind, induces sweat, stops blooding.Cure mainly the diseases such as cold, fever, headache, eye itching, cough, laryngopharynx swelling and pain, measles, carbuncle, there is following pharmacological action: 1. antipyretic-antalgic, 2. resisting pathogenic microbes effect, 3. anastalsis, 4. other effect: the effect such as anticancer, antiinflammatory.
Cornu Bovis seu Bubali silk: Cornu Bovis seu Bubali silk has heat-clearing and toxic substances removing, kind clearing away heat from blood, is usually used in warm febrile disease is joined the army, heat in blood contains heated high heat, coma; Also have the effect of cooling blood for hemostasis, can removing heat from blood with clearing away heat from blood, send out speckle, epistaxis for bleeding due to blood-heat.Be usually used in the disease such as treatment wind heat headache, calentura stupor, numb pox, macule, larynx pharyngeal swelling.
Taurine: taurine has another name called taurine, Taurine is a kind of non-protein amino acid of sulfur-bearing, and taurine used in the present invention is separated from Fel Bovis seu Bubali, is a kind of nutrient substance with extensive biological function.Due to its special biological effects of taurine, its application in aquaculture is the focus that zoologist studies always.A large amount of poultry results of study proves, and taurine can improve growth performance, fertility, improves immunity etc.Make a concrete analysis of as follows:
1. improve growth performance: although taurine does not participate in Protein synthesis, in daily ration, add the utilization rate that appropriate taurine can improve protein, thus indirectly promote animal growth.In addition, taurine promotes that fat and fatsoluble vitamin are digested and assimilated, and be combined with bile acid and form taurocholic acid, taurocholic acid is required for digesting and assimilating of lipid in digestive tract.Raising growth performance in, taurine to different aquatic animal, as Paralichthys olivaceus, jewfish, Ctenopharyngodon idellus, Cyprinus carpio etc. show certain diversity.
2. reproductive performance is improved: taurine is normal pregnancy, childbirth, young stock survive the required nutrient substance with normal development.Lack and miscarriage, stillborn fetus, fertility then can be caused to decline and young stock growth retardation.Meanwhile, taurine is the component of antioxidant system in body, and in this system, taurine is Water-soluble antioxidant material, can maintain the anti-oxidative defense of sperm and embryonal tissue, thus plays an important role in the breeding of birds.
3. improve immunity: most of histiocyte, the taurine especially containing high concentration in inflammatory cell (as phagocyte), this may be closely related with the function of its improvement immunity of organisms.Taurine can react with the hypochlorous acid produced with peroxide enzymatic pathway, and generate the taurine-chlorine stablizing low toxicity, in body, haloid acid is the causative factors of injury of inflammation, and taurine removes them by such process, reduces the injury of inflammation.Lot of experiments confirms equally, and taurine-chlorine is a kind of powerful immunomodulator, plays a key effect in innate immunity.Taurine-chlorine can be used for treating various infection popular at present to have scholar to think, comprises chronic inflammatory diseases etc.
Shikimic acid: shikimic acid is a kind of monomeric compound extracted from Chinese medicine Fructus Anisi Stellati, there is following pharmacological action: 1. antibacterial antitumor action 2. antithrombotic and cerebral ischemia: shikimic acid has obvious anti thrombotic action, can suppress the formation of artery and vein thrombosis and cerebral thrombosis, shikimic acid and derivant thereof also have treating cerebral ischemia.3. antiinflammatory action.
4. anti-avian influenza effect: human health and social stability in the bird flu epidemic situation serious harm that spreads fast in the world.At present, the anti-avian influenza patent drug " oseltamivir phosphate capsule " that Roche Holding Ag of Switzerland produces is that unique one can clinically to the medicable medicine of bird flu virus, and it has obvious inhibitory action to H5N1 type bird flu.Antiviral ingredients Oseltamivir in " oseltamivir phosphate capsule " is a kind of derivant transformed shikimic acid structure further and obtain.Oseltamivir phosphate capsule is a kind of neural ammonia inhibitor, it is the esterified prodrug of Oseltamivir carboxylate, Oseltamivir carboxylate is then the inhibitor that a kind of infected by influenza A and B neuraminidase (NA) have powerful selective, spreads all over whole body and play drug effect in liver after can being converted into its active metabolite.In vitro in experiment, it all has powerful antiviral activity to all influenza A and B strain (comprising H5N1 and H9N2 recently infecting the mankind in Hong Kong).All prove with experiment in vitro in body, Oseltamivir carboxylate is all effective to the infection of prevention and therapy influenza A and B, and has good toleration.By comparing discovery with bird flu inhibitor amantadine and rimantadine, oseltamivir has broader antiviral spectrum, the side effect lighter than amantadine, and cause can the tendentiousness of hereditary drug resistance strain less.
Shikimic acid is antiviral class medicine, all has comparatively high inhibition effect to various DNA and RNA viruses disease, especially the influenza caused by subtype influenza virus such as H5N1, H9N2 is had to the effect for the treatment of and prevention.Be mainly used in the viral diseases such as control avian influenza, infectious bronchitis, infectious laryngotracheitis, newcastle, infectious bursa of Fabricius clinically.
The pharmacological action of shikimic acid has following characteristics: 1. drug effect is more lasting: while this product plays drug effect in vivo, and in its body, derivatization product has antivirus action equally, and thus the efficacy stability time is longer; 2. model of action is unique
:direct suppression virion discharges from cell, thus stops it to infect normal cell further, plays the effect of rapid symptom management; 3. treating both the principal and secondary aspects of a disease: playing antiviral while, has antiinflammatory and analgesic effect concurrently.
Gypsum Fibrosum: Gypsum Fibrosum used in the present invention is natural dihydrate gypsum (CaSO42H2O), be also called Gypsum Fibrosum, Gypsum Fibrosum has refrigeration function, to normal body temperature without cooling effect, and to artificial fever animal, there is certain refrigeration function, there is obvious antipyretic effect to artificial fever rabbit.
Borneolum Syntheticum: this product is that the resin of Spore density Borneolum Syntheticum and the crystallization of volatile oil processed goods extraction acquisition are processed into.Borneolum Syntheticum acrid in the mouth, hardship, to be slightly cold; GUIXIN, liver, lung meridian; Delicate fragrance a surname is loose, has refreshment of having one's ideas straightened out, and the loose poison of heat clearing away, effect of improving acuity of vision and removing nebula, cures mainly calentura unconsciousness due to high fever, apoplexy syncope due to accumulation of phlegm infantile convulsion, and heat-damp in summer hoodwinks key clearly, and sore throat is deaf, and aphtha tooth swells, carbuncle sore infantile malnutrition hemorrhoid, conjunctival congestion and swelling pain.
Herba Menthae: Herba Menthae is one of Chinese conventional Chinese medicine is pungent cool property sweating antipyretic medicine, is usually used in controlling influenza, the disease such as headache, conjunctival congestion, fever of the body, throat, dental bed swell and ache.Modern medicine study proves that Herba Menthae has following medicinal efficacy: (1) antivirus action; (2) ease pain itching-relieving action; (3) irritation, antitussive action: the irritation effect of Mentholum causes trachea to produce new secretion, and make the mucus of stiff be easy to discharge, therefore have phlegm-dispelling functions, Mentholum also has good antitussive action.(4) bactericidal action: Herba Menthae has extremely strong sterilization antibacterial action, often drinks its energy preventing viral flu, oral disease, makes breath freshening.(5) physiological function: Herba Menthae is the best quintessence oil for the treatment of flu, can suppress fever and mucosa inflammation, can also promote perspire, cleaning throat and moistening larynx, elimination halitosis; Also there is effect of relieveing pain and refreshing, headache, migraine and toothache can be alleviated; In addition for respiratory system, digestive system, hormonal system, good effect is had.
Herba Violae: Herba Violae has heat-clearing and toxic substances removing, removing heat from blood is subsided a swelling, the effect of clearing away heat-damp and promoting diuresis.Flavonoid glycosides contained by Herba Violae and organic acid have stronger bacteriostasis to gold-coloured staphylococci, pig pasteurellosis bacillus, escherichia coli, streptococcus and Salmonella.Institute's Rich in Trace Element, effect is had to the activity of enzyme multiple in human body, direct or indirect effect is had to the synthesis of nucleic acid-protein, immunologic process, cell proliferation, epithelial cell reparation can be promoted, cell division is increased, and T cell increases, active increase, thus the immunologic function of organism is played regulatory role, play the regulation and control to organism metabolism by enzyme system.Contained zinc can antiviral, and can stimulate antitoxic synthesis, and improving the resistance to infectious disease, is the basis of its " heat-clearing and toxic substances removing ", " controlling cellulitis treatment malicious ".
Rhizoma Phragmitis: this product is sweet in flavor and cold in property, lung gastric qi can divide excess-heat clearly thoroughly, again can promoting the production of body fluid to quench thirst, relieving restlessness, therefore availablely control consumption of body fluid caused by febrile disease, dysphoria with smothery sensation thirster, Rhizoma Phragmitis has treatment cough due to lung-heat, lung abscess vomiting pus, and gastric heat is vomitted effect of the sound of vomiting, the puckery pain of pyretic stranguria.
Radix Isatidis: Radix Isatidis has effect of heat-clearing and toxic substances removing, removing heat from blood detumescence, sore-throat relieving.Medical research proves, Radix Isatidis has following medicinal efficacy: (1) resisting pathogenic microbes effect: Radix Isatidis has inhibitory action to various bacteria. infusion has inhibitory action in various degree to bacillus subtilis, staphylococcus aureus, sarcine, escherichia coli, Bacillus typhi, Salmonella paratyphi, dysentery (will congratulate, Fu Shi) bacillus, bacillus enteritidis etc.; And effective to Hemolytic streptococcus. similar to bacteriostasis and the Bulbus Allii of A type meningococcus, Flos Lonicerae. infected by influenza PR8 strain and Jing Ke 68-1 strain have obvious inhibitory action. and in vitro leptospiral effect killed by Radix Isatidis.(2) to cardiovascular effect: experiment proves, these product can make the in vitro rabbit ear and rat lower limb perfusion flow increase, and improve Rabbit Mesentery microcirculation, reduce the blood pressure of Anaesthetic Rabbits, reduce capillary permeability, and mouse cardiac muscle oxygen consumption is declined.
Beneficial effect: the present invention is carrying out on the basis of large quantity research to influenza multiple clinically, influenza, in conjunction with the pharmacodynamic profile of Chinese medicine and Effective Component of Chinese Medicine, and has carried out abundant checking by a series of clinical trial.By three-dimensional prescription, by antitussive, eliminate the phlegm, antiviral, antibacterial, improve the object that effect of immunity of organisms reaches treating both the principal and secondary aspects of a disease, the factor of causing a disease is considered comprehensively, adopt Chinese medicine extract, the Chinese medicinal powder with unique effects is re-dubbed compound preparation, there is antiinflammatory, sterilization, antiviral, heart tonifying, antitussive, antiallergic action, promote poultry anti pathologic immunity power, repair impaired mucosa, effectively control the effects such as secondary infection, have efficient therapeutical effect to avian influenza, influenza.Formula of the present invention rationally, simple, the Be very effective of science, preparation, to be widely used, can be used as the choice drug of prevention and therapy avian influenza, influenza.
Detailed description of the invention
Below in conjunction with preferred embodiment, the present invention will be further described.
Embodiment 1: the powder taking following raw materials according according to following proportioning respectively: Herba Schizonepetae 160g, Cornu Bovis seu Bubali silk 65g, taurine 25g, shikimic acid 40g, Gypsum Fibrosum 110g, Borneolum Syntheticum 2g, Herba Menthae 120g, Herba Violae 100g, Rhizoma Phragmitis 50g, Radix Isatidis 30g; mix homogeneously, namely make a kind of green, efficient, have no drug resistance, the Chinese traditional compound medicine for preventing and treating birds anemofrigid cold, influenza for the treatment of both the principal and secondary aspects of a disease.Described raw material is commercially available prod.Taurine used is the taurine extracting (extracting from the product such as Fel Bovis seu Bubali, fish and shellfish) in natural biological product.
Embodiment 2: the powder taking following raw materials according according to following proportioning respectively: Herba Schizonepetae 130g; Cornu Bovis seu Bubali silk 53g; taurine 16g, shikimic acid 25g, Gypsum Fibrosum 140g, Borneolum Syntheticum 2.5g; Herba Menthae 145g; Herba Violae 90g; Rhizoma Phragmitis 75g, Radix Isatidis 50g, mix homogeneously, namely makes a kind of green, efficient, noresidue, has no drug resistance, the Chinese traditional compound medicine for preventing and treating birds anemofrigid cold, influenza for the treatment of both the principal and secondary aspects of a disease.Described raw material is commercially available prod.Taurine used is the taurine extracting (extracting from the product such as Fel Bovis seu Bubali, fish and shellfish) in natural biological product.Described shikimic acid is a kind of monomeric compound extracted from Chinese medicine Fructus Anisi Stellati.
Embodiment 3: the powder taking following raw materials according according to following proportioning respectively: Herba Schizonepetae 190g; Cornu Bovis seu Bubali silk 75g; taurine 30g, shikimic acid 55g, Gypsum Fibrosum 82g, Borneolum Syntheticum 1g; Herba Menthae 85g; Herba Violae 140g; Rhizoma Phragmitis 30g, Radix Isatidis 13g, mix homogeneously, namely makes a kind of green, efficient, noresidue, has no drug resistance, the Chinese traditional compound medicine for preventing and treating birds anemofrigid cold, influenza for the treatment of both the principal and secondary aspects of a disease.Described raw material is commercially available prod.Taurine used is the taurine extracting (extracting from the product such as Fel Bovis seu Bubali, fish and shellfish) in natural biological product.Described shikimic acid is a kind of monomeric compound extracted from Chinese medicine Fructus Anisi Stellati.
Embodiment 4: the powder taking following raw materials according according to following proportioning respectively: Herba Schizonepetae 145g; Cornu Bovis seu Bubali silk 62g; taurine 29g, shikimic acid 32g, Gypsum Fibrosum 95g, Borneolum Syntheticum 1.7g; Herba Menthae 125g; Herba Violae 129g; Rhizoma Phragmitis 68g, Radix Isatidis 16g, mix homogeneously, namely makes a kind of green, efficient, noresidue, has no drug resistance, the Chinese traditional compound medicine for preventing and treating birds anemofrigid cold, influenza for the treatment of both the principal and secondary aspects of a disease.Described raw material is commercially available prod.Taurine used is the taurine extracting (extracting from the product such as Fel Bovis seu Bubali, fish and shellfish) in natural biological product.Described shikimic acid is a kind of monomeric compound extracted from Chinese medicine Fructus Anisi Stellati.
Embodiment 5: the powder taking following raw materials according according to following proportioning respectively: Herba Schizonepetae 175g; Cornu Bovis seu Bubali silk 68g; taurine 21g, shikimic acid 47g, Gypsum Fibrosum 128g, Borneolum Syntheticum 2.4g; Herba Menthae 104g; Herba Violae 93g; Rhizoma Phragmitis 43g, Radix Isatidis 38g, mix homogeneously, namely makes a kind of green, efficient, noresidue, has no drug resistance, the Chinese traditional compound medicine for preventing and treating birds anemofrigid cold, influenza for the treatment of both the principal and secondary aspects of a disease.Described raw material is commercially available prod.Taurine used is the taurine extracting (extracting from the product such as Fel Bovis seu Bubali, fish and shellfish) in natural biological product.Described shikimic acid is a kind of monomeric compound extracted from Chinese medicine Fructus Anisi Stellati.
Embodiment 6: the powder taking following raw materials according according to following proportioning respectively: Herba Schizonepetae 160g; Cornu Bovis seu Bubali silk 65g; taurine 26g, shikimic acid 38g, Gypsum Fibrosum 110g, Borneolum Syntheticum 2g; Herba Menthae 117g; Herba Violae 118g; Rhizoma Phragmitis 55g, Radix Isatidis 27g, mix homogeneously, namely makes a kind of green, efficient, noresidue, has no drug resistance, the Chinese traditional compound medicine for preventing and treating birds anemofrigid cold, influenza for the treatment of both the principal and secondary aspects of a disease.Described raw material is commercially available prod.Described shikimic acid is a kind of monomeric compound extracted from Chinese medicine Fructus Anisi Stellati.
Embodiment 7: the powder taking following raw materials according according to following proportioning respectively: Herba Schizonepetae 160g, Cornu Bovis seu Bubali silk 60g, taurine 25g, shikimic acid 40g, Gypsum Fibrosum 100g, Borneolum Syntheticum 1g, Herba Menthae 100g, Herba Violae 100g, Rhizoma Phragmitis 50g, Radix Isatidis 30g.Mix homogeneously, namely makes a kind of green, efficient, noresidue, has no drug resistance, the Chinese traditional compound medicine for preventing and treating birds anemofrigid cold, influenza for the treatment of both the principal and secondary aspects of a disease.Described raw material is commercially available prod.Taurine used is the taurine extracting (extracting from the product such as Fel Bovis seu Bubali, fish and shellfish) in natural biological product.Described shikimic acid is a kind of monomeric compound extracted from Chinese medicine Fructus Anisi Stellati.
Using method: with this product medicine 1000g spice 1000kg, be used in conjunction 5-7 days, during prevention, dose can reduce by half.
Effect: be applicable to control birds anemofrigid cold, influenza, there is the chicken group that obvious respiratory symptom, mortality rate are high, feed intake sharply declines, by the therapeutic efficiency of Chinese medicine uniqueness, respiratory symptom can be controlled at short notice, reduce chicken group stress, be conducive to chicken group disease recovery.
Claims (5)
1. for preventing and treating an oral administered compound Chinese medicine preparation for birds anemofrigid cold, influenza, it is characterized in that: this Chinese medicine preparation is made up of the raw material mix homogeneously of following parts by weight: Herba Schizonepetae 120 ~ 200 parts, Cornu Bovis seu Bubali silk 50 ~ 80 parts, taurine 15 ~ 35 parts, shikimic acid 20 ~ 60 parts, 80 ~ 150 parts, Gypsum Fibrosum, Borneolum Syntheticum 1 ~ 3 part, Herba Menthae 80 ~ 150 parts, Herba Violae 80 ~ 150 parts, Rhizoma Phragmitis 30 ~ 80 parts, Radix Isatidis 10 ~ 50 parts.
2. oral administered compound Chinese medicine preparation according to claim 1, is characterized in that: described Chinese medicine preparation is made up of the raw material mix homogeneously of following parts by weight: Herba Schizonepetae 140 ~ 180 parts, Cornu Bovis seu Bubali silk 60 ~ 70 parts, taurine 20 ~ 30 parts, shikimic acid 30 ~ 50 parts, 90 ~ 130 parts, Gypsum Fibrosum, Borneolum Syntheticum 1.5 ~ 2.5 parts, Herba Menthae 100 ~ 130 parts, Herba Violae 90 ~ 130 parts, Rhizoma Phragmitis 40 ~ 70 parts, Radix Isatidis 15 ~ 40 parts.
3. oral administered compound Chinese medicine preparation according to claim 1, is characterized in that: described Chinese medicine preparation is made up of the raw material mix homogeneously of following parts by weight: Herba Schizonepetae 160 parts, Cornu Bovis seu Bubali silk 60 parts, taurine 25 parts, shikimic acid 40 parts, 100 parts, Gypsum Fibrosum, Borneolum Syntheticum 1 part, Herba Menthae 100 parts, Herba Violae 100 parts, Rhizoma Phragmitis 50 parts, Radix Isatidis 30 parts.
4. the oral administered compound Chinese medicine preparation according to any one of claim 1-3, is characterized in that: described taurine is the taurine extracted in natural biological product.
5. the oral administered compound Chinese medicine preparation according to any one of claim 1-3, is characterized in that: described shikimic acid is a kind of monomeric compound extracted from Chinese medicine Fructus Anisi Stellati.
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| CN108743705A (en) * | 2018-08-14 | 2018-11-06 | 南宁市黄陈生猪养殖场 | A kind of Chinese medicine preparation of prevention birds influenza |
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| CN102397408A (en) * | 2011-11-21 | 2012-04-04 | 郑州百瑞动物药业有限公司 | Compound antiviral oral liquid for poultry and preparation method thereof |
| CN102845638A (en) * | 2012-08-31 | 2013-01-02 | 杨高林 | Duck feed capable of preventing and treating avian influenza and Chinese herbal additive used therein |
| CN103463609A (en) * | 2013-09-27 | 2013-12-25 | 常州市第一人民医院 | Traditional Chinese medicine oral decoction for treating upper respiratory infection and preparation method for Chinese patent medicine of traditional Chinese medicine oral decoction |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102397408A (en) * | 2011-11-21 | 2012-04-04 | 郑州百瑞动物药业有限公司 | Compound antiviral oral liquid for poultry and preparation method thereof |
| CN102845638A (en) * | 2012-08-31 | 2013-01-02 | 杨高林 | Duck feed capable of preventing and treating avian influenza and Chinese herbal additive used therein |
| CN103463609A (en) * | 2013-09-27 | 2013-12-25 | 常州市第一人民医院 | Traditional Chinese medicine oral decoction for treating upper respiratory infection and preparation method for Chinese patent medicine of traditional Chinese medicine oral decoction |
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