CN103656320A - Oral compound traditional Chinese medicine preparation for preventing poultry chill cold and flu - Google Patents

Oral compound traditional Chinese medicine preparation for preventing poultry chill cold and flu Download PDF

Info

Publication number
CN103656320A
CN103656320A CN201310729236.4A CN201310729236A CN103656320A CN 103656320 A CN103656320 A CN 103656320A CN 201310729236 A CN201310729236 A CN 201310729236A CN 103656320 A CN103656320 A CN 103656320A
Authority
CN
China
Prior art keywords
parts
chinese medicine
medicine preparation
herba
traditional chinese
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201310729236.4A
Other languages
Chinese (zh)
Other versions
CN103656320B (en
Inventor
刘长斗
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NANYANG XINXIANFENG PHARMACEUTICAL Co Ltd
Original Assignee
NANYANG XINXIANFENG PHARMACEUTICAL Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NANYANG XINXIANFENG PHARMACEUTICAL Co Ltd filed Critical NANYANG XINXIANFENG PHARMACEUTICAL Co Ltd
Priority to CN201310729236.4A priority Critical patent/CN103656320B/en
Publication of CN103656320A publication Critical patent/CN103656320A/en
Application granted granted Critical
Publication of CN103656320B publication Critical patent/CN103656320B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Landscapes

  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention discloses an oral compound traditional Chinese medicine preparation for preventing poultry chill cold and flu. The traditional Chinese medicine preparation is prepared from the following raw materials in parts by weight through even mixing: 120-200 parts of schizonepeta, 50-80 parts of ox horn wire, 15-35 parts of taurine, 20-60 parts of shikimic acid, 80-150 parts of gypsum, 1-3 parts of borneol, 80-150 parts of mint, 80-150 parts of herba violae, 30-80 parts of rhizoma phragmitis, and 10-50 parts of isatis root. The compound preparation is compounded by adopting traditional Chinese medicine extracts and traditional Chinese medicine powder with unique effects, has the effects of diminishing inflammation, killing bacteria, resisting virus, strengthening heart, relieving cough, resisting allergic reaction, improving poultry disease resisting immunity, repairing damaged mucous membranes and effectively controlling secondary infection, and has efficient treating effect on the poultry influenza and flu. The oral compound traditional Chinese medicine preparation has the advantages of reasonable and scientific formula, simple preparation, prominent effect and wide application, and can be used as the priority drug for preventing and treating the poultry influenza and flu.

Description

For preventing and treating the oral administered compound Chinese medicine preparation of birds anemofrigid cold, influenza
Technical field
The present invention relates to a kind of fowl medicine, particularly relate to a kind of for preventing and treating the oral administered compound Chinese powder medicine of birds anemofrigid cold, influenza.
Background technology
Aquaculture is the pillar industry in modern agriculture, and the sustainable and stable development of aquaculture is for promoting the development of modern agriculture and the material support of uplifting the people's living standard and providing strong.But the level of China's cultivation is at present relatively backward, some small-sized raisers lack management system and the technological means of science, driven by interests, adopt inappropriate method for breeding and means to produce inferior even poisonous animal products.In feeding process, abuse antimicrobial drug, cause on the one hand that medicine is residual to exceed standard, serious harm people's health, has promoted the generation of " superbacteria " on the other hand.In several past years, the events such as " clenbuterol hydrochloride ", tripolycyanamide in rapid succession, have caused and have had a strong impact on people's healthy and consumer psychology.Therefore, science healthy aquaculture and standardization medication are current aquaculture problems in the urgent need to address.That Chinese herbal medicine and preparation thereof have is nontoxic, noresidue, be difficult for producing the advantages such as drug resistance, and China's Chinese herbal medicine resource is abundant, has shown academic significance, practical value and unlimited prospect more and more important in herbal control.And anemofrigid cold, influenza (comprising influenza) are one of major diseases of harm aquaculture always, therefore, a kind of prescription science is provided, without drug resistance, evident in efficacy for preventing and treating the Chinese traditional compound medicine of birds anemofrigid cold, influenza, become one of this those skilled in the art's problem demanding prompt solution.
In the with a long history and abundant achievement of China's application herbal control livestock and poultry.Over nearly more than 10 years, the development of intensive culture industry, numerous veterinarys scientific worker and cultivation worker are in scientific experiments and production practices, use theoretical system and the application form of Chinese medicine uniqueness, in conjunction with features such as the physiology of animal, pathology, probe boldly, constantly bring forth new ideas, develop Chinese herbal medicine resource, in diseases prevention and treatment, obtained important breakthrough and gratifying development.Application Chinese herbal medicine not only can be treated, and can prevent; Not only can prevent and treat common disease, can also prevent and treat infectious disease, even in the control of deadly infectious disease, also obtain compellent effect; Also, from individual treatment to mass prevention and mass treatment, adapt to the needs of intensive farm; Particularly Chinese herbal medicine nonspecific immunity is prevented and treated exploration and the breakthrough of aspect, not only proved that Chinese herbal medicine has science and has again actuality, and at home and abroad medical domain causes huge science and technology change.
The application of Chinese herbal medicine in aquaculture: the preparation being comprised of Chinese herbal medicine is a lot, has a wide range of applications in livestock breeding industry.Its Main Function has immunostimulant, the weightening finish of fattening, anti-bacteria and anti-virus, anthelmintic, growth-promoting is grown and lactogenic, seasoning, painted, fresh-keeping etc.Now with regard to the various application features of Chinese herbal and crude drugs preparations, simply introduce.
Chinese medicine immunity enhancer: Chinese herbal medicine strengthens immune composition and mainly contains polysaccharide, organic acid, alkaloid, glycoside and volatile oil.The mechanism of its effect is that 1. Chinese herbal medicine can promote the growth of Immune Organs of Body; 2. the immunologic enhancement of Chinese herbal medicine to leukocyte and monocytes/macrophages system; 3. the facilitation of Chinese herbal medicine to natural killer cell; 4. the facilitation of Chinese herbal medicine to cytokine; 5. the facilitation of Chinese herbal medicine to cellular immunization; 6. the facilitation of Chinese herbal medicine to humoral immunization; 7. the two-way immunoregulation effect of Chinese herbal medicine, much Chinese medicine or its active ingredient are dual regulation to body's immunity, and the one, the two-way immunoregulation effect of dose dependent, the one, the two-way immunoregulation effect of activity-dependent.The two-way immunoregulation effect of dose dependent shows as low dose (or low concentration) and promotes body's immunity, and heavy dose of (or high concentration) suppresses body's immunity; And the two-way immunoregulation effect of activity-dependent can make body machine disorder (hyperfunction or low) immune state recover normal.
Chinese herbal antibacterial agent and anthelmintic: in the middle of Chinese herbal medicine, have some fine antibacterial and anthelmintics, as the Radix Dichroae of Chinese medicine anthelmintic Semen Arecae, Fructus Quisqualis, Herba Buddlejae Lindleyanae and anticoccidial, the Radix Pulsatillae etc.And most Chinese herbal medicine is that to take eliminating evil double righting be major function, these Chinese herbal antibacterial anti-infective action principles mainly comprise virulence (aggressivity and toxin) or the direct killing power to microorganism, body tissue but play and strengthen organ-tissue antibacterial functions, strengthen reticuloendothelial system phagocytic function and inducement interferon and the antianaphylactic effect of other antiinflammatory.These specific functions in view of Chinese herbal medicine, be highly suitable for the diseases prevention and treatment of ecological cultivation farm, particularly, for the plant's (as supported eel field, prawn field, outlet barren sow field) that produces outlet animal product, Chinese herbal medicine has more been brought into play absolute irreplaceable advantage.
The Chinese herbal medicine weighting agent of fattening: adopt Chinese herbal medicine as the weightening finish preparation of fattening of poultry, in the existing long history of China, particularly in eighties of last century after the eighties, started again the upsurge of Chinese herbal feed additive, nowadays this class additive almost relates to all poultry and aquatic animal, and style is a lot of.On current Chinese herbal feed additive market, the Chinese herbal feed additive most species of pig, its function has dyspepsia and intestinal stasis relieving, regulating qi-flowing for strengthening spleen, expelling intestinal worms and removing food stagnancy, evil removing heat clearing away etc.
Growth-promoting is grown the hormonelike Chinese herbal and crude drugs preparations with lactogenic: growth-promoting grow hormonelike Chinese herbal and crude drugs preparations with lactogenic mainly refer to those can QI and blood regulating, tonify Qi of the kidney, spermatogenesis ovulation, vigorous mammary gland, promote the sexual maturity and the Chinese herbal and crude drugs preparations of gonadal hormone sample.Motherland's theory of medicine thinks, the reproduction of animal body is body equilibrium between yin and yang, internal organs coordination, essence and blood and suitable embodiment.Each internal organs of reproduction and body are closely related, and led by kidney, because kidney is hidden congenital essence, also relevant to liver spleen, because blood stored in the liver, the spleen being the foundation of acquired constitution, and the spleen governs the blood.So this class Chinese herbal medicine focuses on the kidney invigorating and essence nourishing blood, need to adjust to animal body is whole determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs.The Chinese herbal medicine of compensate qi and blood has the Radix Astragali, Radix Codonopsis, Radix Angelicae Sinensis, slender acanthopanax, Radix Glycyrrhizae etc.; The Chinese herbal medicine of the kidney invigorating and essence nourishing has the Cortex Eucommiae, Radix Morindae Officinalis, Herba Epimedii, Fructus Psoraleae, Semen Cuscutae etc.; The Chinese herbal medicine of induced ovulation of promoting the sexual maturity has Herba Epimedii, Actinolitum, Semen Trigonellae, Rhizoma Curculiginis and Flos lupuli (Flos Humuli Lupuli) etc.; The Chinese herbal medicine of lactogenic has Semen Vaccariae, Squama Manis, Radix Rhapontici, Sargassum etc.
Anti-stress Chinese herbal and crude drugs preparations: stress cause animal growth slow, systematic function obstacle, fertility performance declines, and product quality is inferior, even can cause that body's immunity weakens and various diseases occurs.Motherland's medical science is six climate exopathogens (wind, cold, summer-heat, wet, dry, fire) and seven emotions (happiness, anger, melancholy, think of, compassion, fear, shy) by destroying the stressor sorted generalization of animal body physiology with mental toughness and automatic regulation function thereof.And in aquaculture, it is heat stress that body is endangered to maximum stressor.And be milch cow and poultry to the most responsive animal of heat stress performance.In the feed additive of anti-heat stress, be mainly at present to take sodium bicarbonate and vitamin C as main alleviant, in addition, also have antipyretic tranquilizer, electrolyte, antibiotics and part trace element etc.Though these Western medicine buffer agent anti-heat stress have certain effect, but the use that chemical drugs is long-term, milch cow and laying hen are easily produced to toxicity, side effect, and residual in Lac Bovis seu Bubali and egg of chemical drugs, have a strong impact on the healthy of the quality of breast, egg and consumer, adopt over the years the experimental study of the anti-heat stress of cow in summer of Chinese herbal feed additive all to obtain good effect.Make a general survey of anti-heat stress Chinese herbal medicine additive, major part is the Chinese herbal medicine of clearing away summer-heat, tonifying QI to produce body fluid and strengthening the spleen and nourishing the stomach, as Gypsum Fibrosum, Folium Nelumbinis, Radix Isatidis, Rhizoma Phragmitis, Radix Paeoniae Alba and so on, action principle aspect, first should clearing away summer-heat, reuse the cooling of Gypsum Fibrosum, Folium Nelumbinis and so on expelling summer-heat, secondly the tired spleen of summer-heat, the most easily affect milch cow and laying hen appetite, cause milk yield and egg production to decline.So adopt the Chinese herbal medicine of strengthening the spleen and nourishing the stomach to promote appetite, strengthen digestion merit, make milch cow and laying hen keep vigorous appetite, guaranteed normal milk production and egg production.
Chinese herbal medicine also can be used as flavoring agent, coloring agent, preserving agent etc.In a word, utilize the characteristics and advantages of Chinese herbal medicine, in aquaculture, widely popularize and apply, solve the ubiquitous drug residue of cultured product and problem of poor quality, by the effect of playing very well in green animal husbandry.
Summary of the invention
Object of the present invention is intended to overcome above-mentioned weak point, a kind of green, efficient, noresidue be provided, have no drug resistance, treating both the principal and secondary aspects of a disease for preventing and treating the Chinese traditional compound medicine of birds anemofrigid cold, influenza.
The technical scheme that the present invention solves its technical problem is: a kind of for preventing and treating the oral administered compound Chinese medicine preparation of birds anemofrigid cold, influenza; this Chinese medicine preparation is made by the raw material mix homogeneously of following parts by weight: 120~200 parts of Herba Schizonepetae; 50~80 parts of Cornu Bovis seu Bubali silk, 15~35 parts of taurines, 20~60 parts of shikimic acids, 80~150 parts, Gypsum Fibrosum, 1~3 part of Borneolum Syntheticum, 80~150 parts of Herba Menthaes, 80~150 parts of Herba Violaes, 30~80 parts of Rhizoma Phragmitiss, 10~50 parts of Radix Isatidis.
Described oral administered compound Chinese medicine preparation is made by the raw material mix homogeneously of following parts by weight: 140~180 parts of Herba Schizonepetae; 60~70 parts of Cornu Bovis seu Bubali silk, 20~25 parts of taurines, 30~40 parts of shikimic acids, 90~130 parts, Gypsum Fibrosum, 1.5~2.5 parts of Borneolum Syntheticums, 100~130 parts of Herba Menthaes, 110~120 parts of Herba Violaes, 40~60 parts of Rhizoma Phragmitiss, 15~35 parts of Radix Isatidis.
Described oral administered compound Chinese medicine preparation is made by the raw material mix homogeneously of following parts by weight: 140~180 parts of Herba Schizonepetae; 60~70 parts of Cornu Bovis seu Bubali silk, 20~30 parts of taurines, 30~50 parts of shikimic acids, 90~130 parts, Gypsum Fibrosum, 1.5~2.5 parts of Borneolum Syntheticums, 100~130 parts of Herba Menthaes, 90~130 parts of Herba Violaes, 40~70 parts of Rhizoma Phragmitiss, 15~40 parts of Radix Isatidis.
Described taurine is the taurine extracting in natural biological product.
Described shikimic acid is a kind of monomeric compound extracting from Chinese medicine Fructus Anisi Stellati.
The pharmacological property of the various medicines of the present invention is analyzed as follows:
Herba Schizonepetae: the medicinal efficacy that Herba Schizonepetae has dispeling the wind, induces sweat, stops blooding.Cure mainly the diseases such as cold, fever, headache, eye itching, cough, laryngopharynx swelling and pain, measles, carbuncle, there is following pharmacological action: 1. antipyretic-antalgic, 2. resisting pathogenic microbes effect, 3. anastalsis, 4. other effect: the effects such as anticancer, antiinflammatory.
Cornu Bovis seu Bubali silk: Cornu Bovis seu Bubali silk has heat-clearing and toxic substances removing, kind clearing away heat from blood, is usually used in warm febrile disease is joined the army, heat in blood is contained heated high heat, coma; Also have the effect of cooling blood for hemostasis, energy removing heat from blood is with clearing away heat from blood, for a speckle, the epistaxis of bleeding due to blood-heat.Be usually used in treating the diseases such as wind heat headache, calentura stupor, numb pox, macule, larynx pharyngeal swelling.
Taurine: taurine has another name called taurine, Taurine, is a kind of non-protein amino acid of sulfur-bearing, and in the present invention, taurine used is separated from Fel Bovis seu Bubali, is a kind of nutrient substance with extensive biological function.Due to its special biological effects of taurine, its application in aquaculture is the focus that zoologist studies always.A large amount of poultry results of study prove, and taurine can improve growth performance, fertility, improves immunity etc.Make a concrete analysis of as follows:
1. improve growth performance: although taurine does not participate in protein biosynthesis, in daily ration, add the utilization rate that appropriate taurine can improve protein, thereby indirectly promote animal growth.In addition, taurine promotes fat and fatsoluble vitamin to digest and assimilate, and is combined forms taurocholic acid with bile acid, and taurocholic acid is essential for digesting and assimilating of lipid in digestive tract.Aspect raising growth performance, taurine is to different aquatic animal, as Paralichthys olivaceus, jewfish, Ctenopharyngodon idellus, Cyprinus carpio etc. show certain diversity.
2. improve reproductive performance: taurine is normal pregnancy, childbirth, young stock survives and the essential nutrient substance of normal development.Lack and can cause miscarriage, stillborn fetus, fertility to decline and young stock growth retardation.Meanwhile, taurine is the component of antioxidant system in body, and in this system, taurine is water solublity antioxidant, can maintain the anti-oxidative defense of sperm and embryonal tissue, thereby play an important role in the breeding of birds.
3. improve immunity: the taurine that contains high concentration in most of histiocytes, especially inflammatory cell (as phagocyte), this function that may improve with it immunity of organisms is closely related.Taurine can react with the hypochlorous acid producing with peroxide enzymatic pathway, generates taurine-chlorine of stablizing low toxicity, and in body, haloid acid is the causative factors of injury of inflammation, and taurine can be removed them by such process, reduces the injury of inflammation.Lot of experiments confirms equally, and taurine-chlorine is a kind of powerful immunomodulator, in innate immunity, plays a key effect.There is scholar to think that taurine-chlorine can be used for treating popular at present various infection, comprise chronic inflammatory diseases etc.
Shikimic acid: shikimic acid is a kind of monomeric compound extracting from Chinese medicine Fructus Anisi Stellati, there is following pharmacological action: 1. 2. antithrombotic and cerebral ischemia of antibacterial antitumor action: shikimic acid has obvious anti thrombotic action, can suppress the formation of artery and vein thrombosis and cerebral thrombosis, shikimic acid and derivant thereof also have treating cerebral ischemia.3. antiinflammatory action.
4. anti-avian influenza effect: human health and social stability in the bird flu epidemic situation serious harm that spreads fast in the world.At present, the anti-avian influenza patent drug " oseltamivir phosphate capsule " that Switzerland Roche Holding Ag produces be unique a kind of can be clinically to the medicable medicine of bird flu virus, it has obvious inhibitory action to H5N1 type bird flu.Antiviral ingredients Oseltamivir in " oseltamivir phosphate capsule " be further transform shikimic acid structure and a kind of derivant.Oseltamivir phosphate capsule is a kind of neural ammonia inhibitor, it is the ethyl esterification prodrug of Oseltamivir carboxylate, Oseltamivir carboxylate is that a kind of infected by influenza A and B neuraminidase (NA) have optionally inhibitor of brute force, spreads all over whole body and brings into play drug effect can be converted into its active metabolite in liver after.In experiment, it all has powerful antiviral activity to all influenza A and B strain (comprising the H5N1 and the H9N2 that recently infect the mankind in Hong Kong) in vitro.In body, all prove with experiment in vitro, Oseltamivir carboxylate is all effective to the infection of prevention and treatment influenza A and B, and has good toleration.By comparing discovery with bird flu inhibitor amantadine and rimantadine, oseltamivir has broader antiviral spectrum, the side effect lighter than amantadine, and cause can hereditary drug resistance strain tendentiousness less.
Shikimic acid is antiviral class medicine, and various DNA and RNA viruses disease are all had to stronger inhibitory action, especially the influenza being caused by subtype influenza viruses such as H5N1, H9N2 is had the effect for the treatment of and prevention.Be mainly used in clinically preventing and treating the viral diseases such as avian influenza, infectious bronchitis, infectious laryngotracheitis, newcastle, infectious bursa of Fabricius.
The pharmacological action of shikimic acid has following characteristics: 1. drug effect is more lasting: when this product is brought into play drug effect in vivo, in its body, derivatization product has antivirus action equally, thereby the efficacy stability time is longer; 2. model of action is unique :directly suppress virion and discharge from cell, thereby stop it further to infect normal cell, play the effect of the rapid control state of an illness; 3. treating both the principal and secondary aspects of a disease: playing the antiviral while, having antiinflammatory and analgesic effect concurrently.
Gypsum Fibrosum: in the present invention, Gypsum Fibrosum used is natural dihydrate gypsum (CaSO42H2O), be called again Gypsum Fibrosum, Gypsum Fibrosum has refrigeration function, to normal body temperature without cooling effect, and artificial fever animal is had to certain refrigeration function, artificial fever rabbit is had to obvious antipyretic effect.
Borneolum Syntheticum: this product is that the resin of Spore density Borneolum Syntheticum and the crystallization of volatile oil processed goods extraction acquisition are processed into.Borneolum Syntheticum acrid in the mouth, hardship, be slightly cold; GUIXIN, liver, lung meridian; Delicate fragrance a surname is loose, has the refreshment of having one's ideas straightened out, the loose poison of heat clearing away, and the effect of improving acuity of vision and removing nebula, cures mainly calentura unconsciousness due to high fever, apoplexy syncope due to accumulation of phlegm infantile convulsion, heat-damp in summer is hoodwinked key clearly, and sore throat is deaf, and aphtha tooth is swollen, carbuncle sore infantile malnutrition hemorrhoid, conjunctival congestion and swelling pain.
Herba Menthae: Herba Menthae is one of Chinese conventional Chinese medicine, is pungent cool property sweating antipyretic medicine, is usually used in controlling influenza, headache, conjunctival congestion, fever of the body, throat, the dental bed disease such as swell and ache.Modern medicine study proof Herba Menthae has following medicinal efficacy: (1) antivirus action; (2) analgesia itching-relieving action; (3) irritation, antitussive action: the irritation effect of Mentholum causes trachea to produce new secretion, and make the mucus of stiff be easy to discharge, therefore there is phlegm-dispelling functions, Mentholum also has good antitussive action.(4) bactericidal action: Herba Menthae has extremely strong sterilization antibacterial action, often drinks its energy preventing viral flu, oral disease, makes breath freshening.(5) physiological function: Herba Menthae is the best quintessence oil for the treatment of flu, can suppress fever and mucosa inflammation, can also promote perspire, cleaning throat and moistening larynx, elimination halitosis; The effect also with relieveing pain and refreshing, can alleviate headache, migraine and toothache; In addition for respiratory system, digestive system, hormonal system, there is good effect.
Herba Violae: Herba Violae has heat-clearing and toxic substances removing, removing heat from blood detumescence, the effect of clearing away heat-damp and promoting diuresis.The contained flavonoid glycosides of Herba Violae and organic acid have stronger bacteriostasis to gold-coloured staphylococci, pig pasteurellosis bacillus, escherichia coli, streptococcus and Salmonella.Institute's Rich in Trace Element, activity to plurality of enzymes in human body has effect, synthetic, the immunologic process of nucleic acid-protein, cell proliferation are had to direct or indirect effect, can promote epithelial cell reparation, cell division is increased, and T cell increases, active increasing, thereby the immunologic function to organism plays regulatory role, by enzyme system, bring into play the regulation and control to organism metabolism.Contained zinc can antiviral, and can stimulate antitoxic syntheticly, improves the resistance to infectious disease, is the basis of its " heat-clearing and toxic substances removing ", " control cellulitis and treat poison ".
Rhizoma Phragmitis: this product is sweet in flavor and cold in property, can be clearly thoroughly lung gastric qi divide excess-heat, again can promoting the production of body fluid to quench thirst, relieving restlessness, therefore available, control consumption of body fluid caused by febrile disease, dysphoria with smothery sensation thirster, Rhizoma Phragmitis has treatment cough due to lung-heat, lung abscess vomiting pus, the gastric heat sound of vomiting of vomitting, the effect of the puckery pain of pyretic stranguria. 
Radix Isatidis: Radix Isatidis has the effect of heat-clearing and toxic substances removing, removing heat from blood detumescence, sore-throat relieving.Medical research proves, Radix Isatidis has following medicinal efficacy: (1) resisting pathogenic microbes effect: Radix Isatidis has inhibitory action to various bacteria. infusion has inhibitory action in various degree to bacillus subtilis, staphylococcus aureus, sarcine, escherichia coli, Bacillus typhi, Salmonella paratyphi, dysentery (will is congratulated, Fu Shi) bacillus, bacillus enteritidis etc.; And effective to Hemolytic streptococcus. similar to the bacteriostasis of A type meningococcus and Bulbus Allii, Flos Lonicerae. the 68-1 of the section strain of infected by influenza PR8Zhu He capital has obvious inhibitory action. and in vitro Radix Isatidis is killed leptospiral effect.(2) to cardiovascular effect: experiment showed, that these product can make the in vitro rabbit ear and rat lower limb perfusion flow increase, improve Rabbit Mesentery microcirculation, reduce the blood pressure of Anaesthetic Rabbits, reduce capillary permeability, and mouse cardiac muscle oxygen consumption is declined.
Beneficial effect: the present invention carries out on the basis of large quantity research in the influenza to multiple clinically, influenza, in conjunction with the drug effect feature of Chinese medicine and Effective Component of Chinese Medicine, and has carried out abundant checking by a series of clinical trial.By three-dimensional prescription, by antitussive, eliminate the phlegm, antiviral, the object that antibacterial, effect that improve immunity of organisms reaches treating both the principal and secondary aspects of a disease, pathogenic factor is considered comprehensively, the Chinese medicinal powder that adopt Chinese medicine extract, has a unique effects is re-dubbed compound preparation, there is antiinflammatory, sterilization, antiviral, heart tonifying, antitussive, antiallergic action, promote poultry anti pathologic immunity power, repair impaired mucosa, effectively control the effects such as secondary infection, avian influenza, influenza are had to efficient therapeutical effect.The present invention fills a prescription rationally, science, preparation is simple, effect is remarkable, be widely used, and can be used as the choice drug of prevention and treatment avian influenza, influenza.
The specific embodiment
Below in conjunction with preferred embodiment, the present invention will be further described.
Embodiment 1: the powder that takes respectively following raw materials according according to following proportioning: Herba Schizonepetae 160g, Cornu Bovis seu Bubali silk 65g, taurine 25g, shikimic acid 40g, Gypsum Fibrosum 110g, Borneolum Syntheticum 2g, Herba Menthae 120g, Herba Violae 100g, Rhizoma Phragmitis 50g, Radix Isatidis 30g; mix homogeneously, make a kind of green, efficient, have no drug resistance, treating both the principal and secondary aspects of a disease for preventing and treating the Chinese traditional compound medicine of birds anemofrigid cold, influenza.Described raw material is commercially available prod.Taurine used is the taurine that extracts (extracting from products such as Fel Bovis seu Bubali, fish and shellfishs) in natural biological product.
Embodiment 2: the powder that takes respectively following raw materials according according to following proportioning: Herba Schizonepetae 130g; Cornu Bovis seu Bubali silk 53g; taurine 16g, shikimic acid 25g, Gypsum Fibrosum 140g, Borneolum Syntheticum 2.5g; Herba Menthae 145g; Herba Violae 90g; Rhizoma Phragmitis 75g, Radix Isatidis 50g, mix homogeneously, make a kind of green, efficient, noresidue, have no drug resistance, treating both the principal and secondary aspects of a disease for preventing and treating the Chinese traditional compound medicine of birds anemofrigid cold, influenza.Described raw material is commercially available prod.Taurine used is the taurine that extracts (extracting from products such as Fel Bovis seu Bubali, fish and shellfishs) in natural biological product.Described shikimic acid is a kind of monomeric compound extracting from Chinese medicine Fructus Anisi Stellati.
Embodiment 3: the powder that takes respectively following raw materials according according to following proportioning: Herba Schizonepetae 190g; Cornu Bovis seu Bubali silk 75g; taurine 30g, shikimic acid 55g, Gypsum Fibrosum 82g, Borneolum Syntheticum 1g; Herba Menthae 85g; Herba Violae 140g; Rhizoma Phragmitis 30g, Radix Isatidis 13g, mix homogeneously, make a kind of green, efficient, noresidue, have no drug resistance, treating both the principal and secondary aspects of a disease for preventing and treating the Chinese traditional compound medicine of birds anemofrigid cold, influenza.Described raw material is commercially available prod.Taurine used is the taurine that extracts (extracting from products such as Fel Bovis seu Bubali, fish and shellfishs) in natural biological product.Described shikimic acid is a kind of monomeric compound extracting from Chinese medicine Fructus Anisi Stellati.
Embodiment 4: the powder that takes respectively following raw materials according according to following proportioning: Herba Schizonepetae 145g; Cornu Bovis seu Bubali silk 62g; taurine 29g, shikimic acid 32g, Gypsum Fibrosum 95g, Borneolum Syntheticum 1.7g; Herba Menthae 125g; Herba Violae 129g; Rhizoma Phragmitis 68g, Radix Isatidis 16g, mix homogeneously, make a kind of green, efficient, noresidue, have no drug resistance, treating both the principal and secondary aspects of a disease for preventing and treating the Chinese traditional compound medicine of birds anemofrigid cold, influenza.Described raw material is commercially available prod.Taurine used is the taurine that extracts (extracting from products such as Fel Bovis seu Bubali, fish and shellfishs) in natural biological product.Described shikimic acid is a kind of monomeric compound extracting from Chinese medicine Fructus Anisi Stellati.
Embodiment 5: the powder that takes respectively following raw materials according according to following proportioning: Herba Schizonepetae 175g; Cornu Bovis seu Bubali silk 68g; taurine 21g, shikimic acid 47g, Gypsum Fibrosum 128g, Borneolum Syntheticum 2.4g; Herba Menthae 104g; Herba Violae 93g; Rhizoma Phragmitis 43g, Radix Isatidis 38g, mix homogeneously, make a kind of green, efficient, noresidue, have no drug resistance, treating both the principal and secondary aspects of a disease for preventing and treating the Chinese traditional compound medicine of birds anemofrigid cold, influenza.Described raw material is commercially available prod.Taurine used is the taurine that extracts (extracting from products such as Fel Bovis seu Bubali, fish and shellfishs) in natural biological product.Described shikimic acid is a kind of monomeric compound extracting from Chinese medicine Fructus Anisi Stellati.
Embodiment 6: the powder that takes respectively following raw materials according according to following proportioning: Herba Schizonepetae 160g; Cornu Bovis seu Bubali silk 65g; taurine 26g, shikimic acid 38g, Gypsum Fibrosum 110g, Borneolum Syntheticum 2g; Herba Menthae 117g; Herba Violae 118g; Rhizoma Phragmitis 55g, Radix Isatidis 27g, mix homogeneously, make a kind of green, efficient, noresidue, have no drug resistance, treating both the principal and secondary aspects of a disease for preventing and treating the Chinese traditional compound medicine of birds anemofrigid cold, influenza.Described raw material is commercially available prod.Described shikimic acid is a kind of monomeric compound extracting from Chinese medicine Fructus Anisi Stellati.
Embodiment 7: the powder that takes respectively following raw materials according according to following proportioning: Herba Schizonepetae 160 g, Cornu Bovis seu Bubali silk 60g, taurine 25 g, shikimic acid 40 g, Gypsum Fibrosum 100 g, Borneolum Syntheticum 1 g, Herba Menthae 100 g, Herba Violae 100 g, Rhizoma Phragmitis 50 g, Radix Isatidis 30 g.Mix homogeneously, make a kind of green, efficient, noresidue, have no drug resistance, treating both the principal and secondary aspects of a disease for preventing and treating the Chinese traditional compound medicine of birds anemofrigid cold, influenza.Described raw material is commercially available prod.Taurine used is the taurine that extracts (extracting from products such as Fel Bovis seu Bubali, fish and shellfishs) in natural biological product.Described shikimic acid is a kind of monomeric compound extracting from Chinese medicine Fructus Anisi Stellati.
Using method: with this product medicine 1000g spice 1000kg, be used in conjunction 5-7 days, during prevention, dose can reduce by half.
Effect: be applicable to prevent and treat birds anemofrigid cold, influenza, there is obvious respiratory symptom, the chicken group that mortality rate is high, feed intake sharply declines, by the therapeutic efficiency of Chinese medicine uniqueness, can control at short notice respiratory symptom, reduce chicken group stress, be conducive to chicken group disease recovery.

Claims (5)

1. for preventing and treating an oral administered compound Chinese medicine preparation for birds anemofrigid cold, influenza, it is characterized in that: this Chinese medicine preparation is made by the raw material mix homogeneously of following parts by weight: 120~200 parts of Herba Schizonepetae, 50~80 parts of Cornu Bovis seu Bubali silk, 15~35 parts of taurines, 20~60 parts of shikimic acids, 80~150 parts, Gypsum Fibrosum, 1~3 part of Borneolum Syntheticum, 80~150 parts of Herba Menthaes, 80~150 parts of Herba Violaes, 30~80 parts of Rhizoma Phragmitiss, 10~50 parts of Radix Isatidis.
2. oral administered compound Chinese medicine preparation according to claim 1, is characterized in that: described Chinese medicine preparation is made by the raw material mix homogeneously of following parts by weight: 140~180 parts of Herba Schizonepetae, 60~70 parts of Cornu Bovis seu Bubali silk, 20~30 parts of taurines, 30~50 parts of shikimic acids, 90~130 parts, Gypsum Fibrosum, 1.5~2.5 parts of Borneolum Syntheticums, 100~130 parts of Herba Menthaes, 90~130 parts of Herba Violaes, 40~70 parts of Rhizoma Phragmitiss, 15~40 parts of Radix Isatidis.
3. oral administered compound Chinese medicine preparation according to claim 1, is characterized in that: described Chinese medicine preparation is made by the raw material mix homogeneously of following parts by weight: 160 parts of Herba Schizonepetae, 60 parts of Cornu Bovis seu Bubali silk, 25 parts of taurines, 40 parts of shikimic acids, 100 parts, Gypsum Fibrosum, 1 part of Borneolum Syntheticum, 100 parts of Herba Menthaes, 100 parts of Herba Violaes, 50 parts of Rhizoma Phragmitiss, 30 parts of Radix Isatidis.
4. according to the oral administered compound Chinese medicine preparation described in claim 1-3 any one, it is characterized in that: described taurine is the taurine extracting in natural biological product.
5. according to the oral administered compound Chinese medicine preparation described in claim 1-3 any one, it is characterized in that: described shikimic acid is a kind of monomeric compound extracting from Chinese medicine Fructus Anisi Stellati.
CN201310729236.4A 2013-12-26 2013-12-26 For preventing and treating the oral administered compound Chinese medicine preparation of birds anemofrigid cold, influenza Active CN103656320B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201310729236.4A CN103656320B (en) 2013-12-26 2013-12-26 For preventing and treating the oral administered compound Chinese medicine preparation of birds anemofrigid cold, influenza

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201310729236.4A CN103656320B (en) 2013-12-26 2013-12-26 For preventing and treating the oral administered compound Chinese medicine preparation of birds anemofrigid cold, influenza

Publications (2)

Publication Number Publication Date
CN103656320A true CN103656320A (en) 2014-03-26
CN103656320B CN103656320B (en) 2016-01-13

Family

ID=50295878

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201310729236.4A Active CN103656320B (en) 2013-12-26 2013-12-26 For preventing and treating the oral administered compound Chinese medicine preparation of birds anemofrigid cold, influenza

Country Status (1)

Country Link
CN (1) CN103656320B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104189231A (en) * 2014-08-19 2014-12-10 郑州马基森生物科技有限公司 Traditional Chinese medicine preparation for resisting virus and enhancing immunity and preparation method thereof
CN108743705A (en) * 2018-08-14 2018-11-06 南宁市黄陈生猪养殖场 A kind of Chinese medicine preparation of prevention birds influenza

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102397408A (en) * 2011-11-21 2012-04-04 郑州百瑞动物药业有限公司 Compound antiviral oral liquid for poultry and preparation method thereof
CN102845638A (en) * 2012-08-31 2013-01-02 杨高林 Duck feed capable of preventing and treating avian influenza and Chinese herbal additive used therein
CN103463609A (en) * 2013-09-27 2013-12-25 常州市第一人民医院 Traditional Chinese medicine oral decoction for treating upper respiratory infection and preparation method for Chinese patent medicine of traditional Chinese medicine oral decoction

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102397408A (en) * 2011-11-21 2012-04-04 郑州百瑞动物药业有限公司 Compound antiviral oral liquid for poultry and preparation method thereof
CN102845638A (en) * 2012-08-31 2013-01-02 杨高林 Duck feed capable of preventing and treating avian influenza and Chinese herbal additive used therein
CN103463609A (en) * 2013-09-27 2013-12-25 常州市第一人民医院 Traditional Chinese medicine oral decoction for treating upper respiratory infection and preparation method for Chinese patent medicine of traditional Chinese medicine oral decoction

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104189231A (en) * 2014-08-19 2014-12-10 郑州马基森生物科技有限公司 Traditional Chinese medicine preparation for resisting virus and enhancing immunity and preparation method thereof
CN108743705A (en) * 2018-08-14 2018-11-06 南宁市黄陈生猪养殖场 A kind of Chinese medicine preparation of prevention birds influenza

Also Published As

Publication number Publication date
CN103656320B (en) 2016-01-13

Similar Documents

Publication Publication Date Title
CN103238756B (en) Compound feed for finishing pigs and preparation method thereof
CN101836691B (en) Chinese medicinal herb feed additive
CN105410346A (en) Cultured penaeus vannamei survival rate improving traditional Chinese medicine preparation and preparation method thereof
CN102920957B (en) Chinese herbal medicine additive for preventing pig salmonellosis and pig feed using additive
CN1251732C (en) Chinese medicine for treating intrapulmonic infection and SARS
CN103083510A (en) Chinese medicinal oral liquid for improving poultry immune function and its preparation method
CN103656320B (en) For preventing and treating the oral administered compound Chinese medicine preparation of birds anemofrigid cold, influenza
CN104322985A (en) Piglet feed
CN110025657B (en) Bacteriostatic traditional Chinese medicine composition, bacteriostatic traditional Chinese medicine preparation, and preparation method and application thereof
CN106511675A (en) Medicine for preventing and treating poultry diseases and preparation method of medicine
CN105535406A (en) Traditional Chinese medicine composition for preventing and treating livestock respiratory disease
CN105106394A (en) Chinese herb preparation for preventing and treating animal digestive canal infection and preparing method and application thereof
CN111760004B (en) Traditional Chinese medicine granules for preventing and treating livestock and poultry influenza and application thereof
CN102793869B (en) Traditional Chinese medicine composition for controlling porcine viral diseases and preparation method thereof
CN103142702A (en) Chinese herbal medicine injection liquid for treating porcine reproductive and respiratory syndrome and preparation method thereof
CN103566312B (en) Traditional Chinese medicine combination for treating loss of appetite of pigs
CN111632092A (en) Traditional Chinese medicine formula for preventing and treating respiratory diseases of livestock and poultry and application thereof
CN102885927A (en) Traditional Chinese medicine composition for treating pullorum disease and preparation method thereof
CN105535720A (en) Chinese herbal medicinal composition for preventing and treating chick bronchitis, and preparation method thereof
CN101314033A (en) Oral liquid synergistic agent for livestock, poultry and aquatic product, and preparation method thereof
CN104606627B (en) A kind of pharmaceutical composition for treating grice diarrhoea and preparation method thereof
CN107648494A (en) One kind treats gingivitis and canker sore Chinese medical collutory and preparation method thereof
CN102228568B (en) Chinese medicine for treating warm heat diseases in livestock and poultry and preparation method thereof
CN101953879B (en) Microbial ecological agent for quickly and efficiently preventing and treating pig high fever
CN106728505A (en) A kind of Chinese medicine composition for treating pig founder

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C53 Correction of patent of invention or patent application
CB03 Change of inventor or designer information

Inventor after: Liu Changdou

Inventor after: Cao Sufang

Inventor before: Liu Changdou

COR Change of bibliographic data

Free format text: CORRECT: INVENTOR; FROM: LIU CHANGDOU TO: LIU CHANGDOU CAO SUFANG

C14 Grant of patent or utility model
GR01 Patent grant