CN101991521A - Tea tree oil mouth wash and preparation method thereof - Google Patents
Tea tree oil mouth wash and preparation method thereof Download PDFInfo
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- CN101991521A CN101991521A CN 201010532283 CN201010532283A CN101991521A CN 101991521 A CN101991521 A CN 101991521A CN 201010532283 CN201010532283 CN 201010532283 CN 201010532283 A CN201010532283 A CN 201010532283A CN 101991521 A CN101991521 A CN 101991521A
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Abstract
The invention relates to mouth wash and a preparation method thereof, in particular to tea tree oil mouth wash with the functions of bacteriostasis, inflammation diminishing and hemostasis and a preparation method thereof. The tea tree oil mouth wash comprises the following components in percentage by weight: 0.01 to 30 percent of tea tree oil, 0.01 to 20 percent of propylene glycol (for medicine or food), 0.01 to 20 percent of Tween-60, 30 to 99.97 percent of distilled water and few additives. In the invention, the tea tree oil is added into the mouth wash, so that the mouth wash can be taken, has no toxic nor side effects, has a wide-spectrum antibacterial property, has high capability of killing many anaerobic bacteria and non-anaerobic bacteria, can reduce gingival inflammation and promote canker sore coalescence, has a remarkable effect of alleviating throat pain and is safe and nonirritating.
Description
[technical field]
The present invention relates to a kind of collutory and preparation method thereof, relate in particular to a kind of tea tree oil collutory and preparation method thereof with antibacterial, antiinflammatory, hemostatic function.
[background technology]
In recent years, along with the raising of quality of life and the enhancing of life taste consciousness, people more and more pay close attention to oral hygiene with healthy, and problems such as gingivitis, periodontitis, gingival hemorrhage, oral ulcer, halitosis become a lot of people's puzzlement.At present, a lot of oral cavity cleaning series products being arranged on the market, have the dental products of better effect few to relevant oral disease, mainly is to lack corresponding effect material base.
Tea tree oil (Tea tree oil) should be titrol according to the botany definition, it mainly from the fresh branch and leaf of Melaleuca Alternifolia (Melabeuca alternifolia) plant of Myrtaceae Melaleuca through steam distillation obtain colourless to flaxen quintessence oil, this quintessence oil claims Australia tea tree oil, and calendar year 2001 is put into European Pharmacopoeia.Therefore people as the existing very long history of drug use, during World War II as the important drugs of soldier's skin damage treatment, and are accepted extensively tea tree oil by the world.Studies show that tea tree oil has that broad-spectrum is antibiotic, antifungal, antiviral and anti-inflammatory activity, can effectively prevent and treat the infection of oral cavity, skin, urinary system, can treat surface injury, can infiltrate deep layer skin performance drug effect, can maintain and promote the metabolism of skin.The nineties in 20th century, China is to the Melaleuca Alternifolia successful introduction, at present in Hainan, all there is establishing in large scale in Guangdong, Guangxi, Yunnan, tea tree oil output has had considerable scale, portioned product is sold abroad.
[summary of the invention]
At foregoing, the purpose of this invention is to provide a kind of tea tree oil that is added with, have antibacterial, antiinflammatory, hemostatic function, mouthfeel is good, tea tree oil collutory easy to use, that problems such as the common periodontitis in oral cavity, gingivitis, gingival hemorrhage, oral ulcer, halitosis are had better curative effect.
For achieving the above object, the technical solution adopted in the present invention is as follows:
A kind of tea tree oil collutory, containing purity is the pure natural tea tree oil of 95%-99%.
Described tea tree oil collutory, contain following component by mass percent:
Constituent content (%)
Tea tree oil 0.01-30
Propylene glycol (medicinal or edible) 0.01-20
Tween-60 0.01-20
Distilled water 30-99.97
Additives 0-1
Described tea tree oil is to extract from bright leaf of Melaleuca Alternifolia and twig by vapor distillation or organic solvent to obtain, and main component is a terpineol-4, and its content is 30%-48%.
Described additives are for adjusting the natural essential oil of taste.
In a preferred embodiment, described natural essential oil is a natural menthence.
In another preferred embodiment, described natural essential oil is a natural lemon oil.
Tea tree oil collutory of the present invention prepares by the following method:
(1) tea tree oil, Tween-60, propylene glycol, additives are mixed successively, stir;
(2) add distilled water and stir, filter, bottling, the tea tree oil collutory that promptly obtains rinsing the mouth or dilute in proportion.
The present invention adds tea tree oil in collutory, it has that broad-spectrum is antibiotic, antifungal, antiviral and anti-inflammatory activity, can effectively treat the infection of oral cavity, skin, urinary system, can treat surface injury, the metabolism of skin can be maintained and promote to infiltration deep layer skin performance drug effect.
Contained tea tree oil is as follows to the minimum inhibitory concentration of different strains anaerobe in the collutory of the present invention:
Tea tree oil to the bacteriostatic test of anaerobe-minimum antibacterial concentrating (MIC, %)
Tea tree oil to the bacteriostatic test of anaerobe-minimum antibacterial concentrating (MIC, %)
Beneficial effect of the present invention is: 1, can be oral: tea tree oil derives from Australia Melaleuca Alternifolia plant, is used to boil tea behind the branch and leaf and drinks because of the original inhabitant adopts, so claim Australia Camellia sinensis again, other components are medicinal or edible adjuvant commonly used, all can be oral; 2, have no side effect: tea tree oil has been listed European Pharmacopoeia in, and is authenticated by U.S. FDA, can use safely; 3, pain relieving can sterilize: collutory of the present invention comprises tea tree oil, tea tree oil has broad spectrum antibacterial, to a lot of anaerobe, non-anaerobe all has good sterilizing ability, its antibacterial ability is stronger 13 times than phenol, and percutaneous permeability is good, add in the collutory as functional material, compare with existing chemical antiinflammatory, tea tree oil is to removing the growth of oral cavity anaerobium, alleviate various focusing depths represented, promote the oral ulcer healing, the effect that alleviates laryngopharynx swelling and pain is remarkable, safety, non-stimulated, can not produce long-time use and the microorganism Drug resistance that forms, the tooth flavescence, negative effects such as oral cavity exsiccation.
[specific embodiment]
The invention will be further described below in conjunction with specific embodiment.
Embodiment 1
By mass percentage with tea tree oil 0.05%, Tween-60 10%, propylene glycol 10%, mixing successively, add the additives trace again, slowly add distilled water 86.95%, be stirred into transparency liquid, filter, bottled, the tea tree oil collutory that promptly obtains direct rinsing the mouth or dilute in proportion.
Embodiment 2
By mass percentage with tea tree oil 0.3%, Tween-60 10%, propylene glycol 10%, mixing successively, add the additives trace again, slowly add distilled water 86.7%, be stirred into transparency liquid, filter, bottled, the tea tree oil collutory that promptly obtains direct rinsing the mouth or dilute in proportion.
Embodiment 3
By mass percentage with tea tree oil 1%, Tween-60 10%, propylene glycol 10%, mixing successively, add the additives trace again, slowly add distilled water 86%, be stirred into transparency liquid, filter, bottled, the tea tree oil collutory that promptly obtains direct rinsing the mouth or dilute in proportion.
Embodiment 4
By mass percentage with tea tree oil 5%, Tween-60 10%, propylene glycol 10%, mixing successively, add the additives trace again, slowly add distilled water 82%, be stirred into transparency liquid, filter, bottled, the tea tree oil collutory that promptly obtains direct rinsing the mouth or dilute in proportion.
Embodiment 5
By mass percentage with tea tree oil 10%, Tween-60 10%, propylene glycol 10%, mixing successively, add the additives trace again, slowly add distilled water 77%, be stirred into transparency liquid, filter, bottled, the tea tree oil collutory that promptly obtains direct rinsing the mouth or dilute in proportion.
Embodiment 6
By mass percentage with tea tree oil 20%, Tween-60 10%, propylene glycol 20%, mixing successively, add the additives trace again, slowly add distilled water 57%, be stirred into transparency liquid, filter, bottled, the tea tree oil collutory that promptly obtains direct rinsing the mouth or dilute in proportion.
Embodiment 7
By mass percentage with tea tree oil 0.3%, Tween-60 10%, propylene glycol 10%, mixing adds natural menthence 0.3% more successively, the additives trace, slowly add distilled water 86.4%, be stirred into transparency liquid, filter, bottled, as promptly to obtain direct rinsing the mouth or dilute in proportion tea tree oil collutory.
Embodiment 8
By mass percentage with tea tree oil 0.3%, Tween-60 10%, propylene glycol 10%, mixing adds natural lemon oil 0.3% more successively, the additives trace, slowly add distilled water 86.4%, be stirred into transparency liquid, filter, bottled, as promptly to obtain direct rinsing the mouth or dilute in proportion tea tree oil collutory.
Embodiment 9
Certain man, 28 years old, pericoronitis, symptom: hat week is red and swollen, purulent secretion is arranged, limitation of mouth opening, diet difficulty.Take the antibiotic medicine, auxiliary used the embodiment of the invention 2 collutorys 3, every day 3-5 rinsing the mouth 30s, pain reduces, use 7 continuously after, swelling is disappeared, dehisce normally, but normal diet.
Embodiment 10
Certain woman, 23 years old, patient's oral ulcer was shown effect nearly 2 years repeatedly, pain with symptoms such as halitosis, heating, lymph enlargements, successively fails to cure at how tame hospital therapy unbearably during sick sending out, work and life have been had a strong impact on, use embodiments of the invention 4 collutorys after 15 days, the state of an illness is clearly better, and halitosis disappears, pain symptom is alleviated, continue to use, oral ulcer complete obiteration after 30 days is not sent out so far.
Claims (7)
1. a tea tree oil collutory is characterized in that containing the pure natural tea tree oil that purity is 95%-99%.
2. tea tree oil collutory as claimed in claim 1 is characterized in that containing following components in weight percentage:
Tea tree oil 0.01-30%
Propylene glycol (medicinal or edible) 0.01-20%
Tween-60 0.01-20%
Distilled water 30-99.97%
Additives 0-1%.
3. tea tree oil collutory as claimed in claim 1 is characterized in that described tea tree oil is to extract from bright leaf of Melaleuca Alternifolia and twig by vapor distillation or organic solvent to obtain, and main component is a terpineol-4, and its content is 30%-48%.
4. tea tree oil collutory as claimed in claim 2 is characterized in that described additives are for adjusting the natural essential oil of taste.
5. tea tree oil collutory as claimed in claim 4 is characterized in that described natural essential oil is a natural menthence.
6. tea tree oil collutory as claimed in claim 4 is characterized in that described natural essential oil is a natural lemon oil.
7. method for preparing as tea tree oil collutory as described in above-mentioned arbitrary claim, it is characterized in that may further comprise the steps: mix tea tree oil, Tween-60, propylene glycol, additives successively (1), stirs; (2) add distilled water and stir, filter, bottling, the tea tree oil collutory that promptly obtains rinsing the mouth or dilute in proportion.
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| Application Number | Priority Date | Filing Date | Title |
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| CN 201010532283 CN101991521A (en) | 2010-11-03 | 2010-11-03 | Tea tree oil mouth wash and preparation method thereof |
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|---|---|---|---|
| CN 201010532283 CN101991521A (en) | 2010-11-03 | 2010-11-03 | Tea tree oil mouth wash and preparation method thereof |
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| CN101991521A true CN101991521A (en) | 2011-03-30 |
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| CN 201010532283 Pending CN101991521A (en) | 2010-11-03 | 2010-11-03 | Tea tree oil mouth wash and preparation method thereof |
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Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102268328A (en) * | 2011-07-08 | 2011-12-07 | 中国热带农业科学院农产品加工研究所 | Method for extracting tea tree oil by microwave radiation |
| CN102911788A (en) * | 2012-09-25 | 2013-02-06 | 华南理工大学 | Water-soluble tea tree oil and method for preparing same |
| CN103191026A (en) * | 2013-04-20 | 2013-07-10 | 五河克菱保健科技有限公司 | Denture adhesive cream |
| CN104586948A (en) * | 2014-10-20 | 2015-05-06 | 恒康医疗集团股份有限公司 | Oral care composition, oral care solution containing same and preparation method of oral care solution |
| CN104740443A (en) * | 2015-04-07 | 2015-07-01 | 范永启 | Traditional Chinese medicine compound essential oil |
| CN104784240A (en) * | 2015-04-28 | 2015-07-22 | 广东工业大学 | Rinse solution containing plant essential oil and preparation method of rinse solution |
| CN105362530A (en) * | 2015-12-11 | 2016-03-02 | 靖州苗族侗族自治县科技推广中心 | Health tea for preventing and treating oral ulcer and nasopharyngitis and preparation method of health tea |
| CN106665700A (en) * | 2016-12-07 | 2017-05-17 | 张树清 | Botanical disinfection composition, disinfectant and preparation method thereof |
| CN108175736A (en) * | 2018-01-22 | 2018-06-19 | 福建美菰林生物科技有限公司 | Gargle and preparation method thereof |
| CN108524606A (en) * | 2017-03-03 | 2018-09-14 | 宁波高新区凡迈科技有限公司 | A kind of tea oil throat sprays |
| CN109568185A (en) * | 2019-01-10 | 2019-04-05 | 德利宝(广州)香料有限公司 | A kind of dentifrice composition and preparation method thereof containing tea oil compounding menthol essence |
| CN110090173A (en) * | 2018-08-21 | 2019-08-06 | 惠州市恒润生物科技有限公司 | A kind of antibacterial anti-inflammatory analgesic toothpaste adding plant essence |
| CN113633614A (en) * | 2021-09-08 | 2021-11-12 | 中国人民解放军陆军军医大学 | Efficient antibacterial natural tea tree essential oil nanoemulsion preparation for treating intractable dental ulcer and preparation method and application thereof |
| WO2023018597A1 (en) * | 2021-08-10 | 2023-02-16 | Prosanus Llc | Oral rinse formulations having essential oils |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1473555A (en) * | 2002-08-07 | 2004-02-11 | 上海辰源香精香料有限公司 | Mouth cavity cleaning essence |
| WO2008079898A1 (en) * | 2006-12-20 | 2008-07-03 | Pharmwest, Inc. | Methods and topical formulations comprising colloidal metal for treating or preventing skin conditions |
-
2010
- 2010-11-03 CN CN 201010532283 patent/CN101991521A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1473555A (en) * | 2002-08-07 | 2004-02-11 | 上海辰源香精香料有限公司 | Mouth cavity cleaning essence |
| WO2008079898A1 (en) * | 2006-12-20 | 2008-07-03 | Pharmwest, Inc. | Methods and topical formulations comprising colloidal metal for treating or preventing skin conditions |
Non-Patent Citations (1)
| Title |
|---|
| 《第三军医大学硕士学文论文》 20060115 王懿 茶树油药理作用的实验研究 第47－49页 1-7 , 2 * |
Cited By (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102268328A (en) * | 2011-07-08 | 2011-12-07 | 中国热带农业科学院农产品加工研究所 | Method for extracting tea tree oil by microwave radiation |
| CN102911788A (en) * | 2012-09-25 | 2013-02-06 | 华南理工大学 | Water-soluble tea tree oil and method for preparing same |
| CN102911788B (en) * | 2012-09-25 | 2014-02-12 | 华南理工大学 | Water-soluble tea tree oil and method for preparing same |
| CN103191026B (en) * | 2013-04-20 | 2015-07-29 | 安徽克菱保健科技有限公司 | Denture adhesive cream |
| CN103191026A (en) * | 2013-04-20 | 2013-07-10 | 五河克菱保健科技有限公司 | Denture adhesive cream |
| CN104586948A (en) * | 2014-10-20 | 2015-05-06 | 恒康医疗集团股份有限公司 | Oral care composition, oral care solution containing same and preparation method of oral care solution |
| CN104740443A (en) * | 2015-04-07 | 2015-07-01 | 范永启 | Traditional Chinese medicine compound essential oil |
| CN104784240B (en) * | 2015-04-28 | 2018-05-08 | 广东工业大学 | A kind of mouthwash containing plants essential oil and preparation method thereof |
| CN104784240A (en) * | 2015-04-28 | 2015-07-22 | 广东工业大学 | Rinse solution containing plant essential oil and preparation method of rinse solution |
| CN105362530A (en) * | 2015-12-11 | 2016-03-02 | 靖州苗族侗族自治县科技推广中心 | Health tea for preventing and treating oral ulcer and nasopharyngitis and preparation method of health tea |
| US10743543B2 (en) | 2016-12-07 | 2020-08-18 | Shuqing Zhang | Botanical disinfection composition, disinfectant and preparation method thereof |
| CN106665700A (en) * | 2016-12-07 | 2017-05-17 | 张树清 | Botanical disinfection composition, disinfectant and preparation method thereof |
| CN106665700B (en) * | 2016-12-07 | 2022-07-26 | 张树清 | Plant-source disinfection composition, disinfectant and preparation method thereof |
| CN108524606A (en) * | 2017-03-03 | 2018-09-14 | 宁波高新区凡迈科技有限公司 | A kind of tea oil throat sprays |
| CN112494413A (en) * | 2018-01-22 | 2021-03-16 | 福建美菰林生物科技有限公司 | Preparation method of gargle with strong antibacterial effect |
| CN108175736B (en) * | 2018-01-22 | 2020-12-01 | 福建美菰林生物科技有限公司 | Gargle and preparation method thereof |
| CN108175736A (en) * | 2018-01-22 | 2018-06-19 | 福建美菰林生物科技有限公司 | Gargle and preparation method thereof |
| CN112494413B (en) * | 2018-01-22 | 2022-12-06 | 邵武市美菰林卫生用品有限公司 | Preparation method of gargle with strong antibacterial effect |
| CN110090173A (en) * | 2018-08-21 | 2019-08-06 | 惠州市恒润生物科技有限公司 | A kind of antibacterial anti-inflammatory analgesic toothpaste adding plant essence |
| CN109568185A (en) * | 2019-01-10 | 2019-04-05 | 德利宝(广州)香料有限公司 | A kind of dentifrice composition and preparation method thereof containing tea oil compounding menthol essence |
| WO2023018597A1 (en) * | 2021-08-10 | 2023-02-16 | Prosanus Llc | Oral rinse formulations having essential oils |
| CN113633614A (en) * | 2021-09-08 | 2021-11-12 | 中国人民解放军陆军军医大学 | Efficient antibacterial natural tea tree essential oil nanoemulsion preparation for treating intractable dental ulcer and preparation method and application thereof |
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Application publication date: 20110330 |