CN108553341A - A kind of composition of suppression acne sterilization - Google Patents
A kind of composition of suppression acne sterilization Download PDFInfo
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- CN108553341A CN108553341A CN201810564359.XA CN201810564359A CN108553341A CN 108553341 A CN108553341 A CN 108553341A CN 201810564359 A CN201810564359 A CN 201810564359A CN 108553341 A CN108553341 A CN 108553341A
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- Prior art keywords
- acne
- composition
- oil
- suppression
- acrylate
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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Abstract
A kind of composition of suppression acne sterilization of the present invention, count by weight percentage, formula includes following components:Hard fat compound 0.1 12.0%;Emulsifier 0.1 8%;Emollient 0.1 30.0%;Moisturizer 0.1 30.0%;Borneol 0.5 30%;Tea oil 0.2 30%;Stabilizer 0.1 10%;Surplus is deionized water.The made clear pox cosmetic of the present invention has the effect of good bactericidal antiphlogistic, maintenance, and can improve the water solubility of borneol and tea oil.
Description
Technical field
The invention belongs to cosmetics, and in particular to a kind of composition of suppression acne sterilization.
Background technology
At present China have people more than 500,000,000 deeply perplexed by whelk, with the development of economy with the continuous improvement of quality of life,
It is influenced by external causes such as South Korean TV soaps and anti-acne asks beautiful rigid need, the anti-acne consciousness of China whelk patient to improve year by year, China
In youth long acne crowd, the quantity for coming into the Best Times of whelk treatment at present drastically expands at high speed, in recent years
Coming anti-acne market has the tendency that outburst.According to statistics, the amount of consumption of China's product for resolving poxes has increased by 800% in nearest 3 years.Expert is pre-
It surveys, in the coming years, China anti-acne market is still the market of high speed development.
Acne is commonly called as whelk, also known as dark sore or acne, is a kind of inflammation being happened at pilosebaceous follicle and its surrounding tissue
Disease lesion, occur in various people especially young man it is more universal, be mainly shown as hoary hair, blackhead, inflamed papules,
The features such as pleomorphism skin lesion such as warts, such as treatment in time, acne print acne hole is gently then remained, it is heavy then disfeature.
Guangzhou, two city list Pharmaceutical retail market of Shenzhen anti-acne class product sales be as high as 74,950,000 yuan, if plus
Channels market, the total sales volumes such as upper quotient is super, cosmetics shop, beauty parlor easily will surpass hundred million.And so on, it is contemplated that entire Guangdong Province dispels
Acne market capacity is up between 1.5-2 hundred million.One do not allow always in the industry marketing personage " thinking highly of eye " anti-acne market, unexpectedly
Contain so big business opportunity, allows people unexpected rather.With marketing education deeply and it is universal, be mistaken in the past " necessary
The whelk of length " " without controlling " is replaced by " easily controlling " " without tired ", market potential also thus rapid expansion, relevant expert
Prediction, in 12 years futures, anti-acne market is still the market of high speed development.
Tea oil is broad spectrum antimicrobial.The pure day extracted from the wood Myrtaceae Cajeputtree Leaf of port in a manner of distillation
Right plants essential oil originates in Australia state.It is colourless to weak yellow liquid, there is the effect of characteristic perfume and antibacterial, anti-inflammatory, expelling parasite, mite killing.
It is pollution-free, non-corrosive, permeability is strong.Treat acne, acne.Its unique fragrant strongly fragrant smell helps to refresh the mind.Chinese at present,
India is also in production tea oil, and domestic main producing region is in Guangxi.Annual output is about tens of tons, is mainly used for exporting, but remote in yield
Not as good as Australia, (refer mainly to 1,8- folium eucalyptis mutually and Foxlene -1- alcohol -4) is also not as good as Australia tea tree in the quality of oil
Oil.
Tea oil is a kind of natural disinfectant, and for treating many diseases, wound has very great help.As cut wound, scratch,
By insect bite, acne, burn, vagina infection, tinea etc..It also be used to control the bacterium and mould in air-conditioning system.Australia is big
Leah tea oil is widely used in cosmetics, toilet articles and veterinary product.The concentration of tea oil is about essentially 15%, for disappearing
Expense person directly makees disinfectant use.
Application of the camellia oil in terms of cosmetics.In terms of beauty, effect of the tea oil in terms of beauty has:Go livid ring around eye and
Pouch moistens lip, reduces pore, and softening skin, sun-proof and radiation protection, despeckle, the acne that disappears, hair care, smoothing wrinkle, makeup, skin care are protected
It is wet etc..Tea oil can thoroughly remove excess oil secretion, adjust water and oil balance, help and dispel acne, prevent small pox and accelerate to fully recover from an illness
More.Moisture content is provided for skin while reinforcing fine and smooth repair ability, is promoted skin smooth, is enabled pore healthier careful.
Application of the camellia oil in terms of food, tea oil use the approval for obtaining the U.S. already, FEMA as food flavor
Number be 3902, it is in bakery product, soft drink, alcoholic beverages, breakfast cereal, cheese, chewing gum, candy, egg products, fish system
In product, grease, frozen dairy product, fruit product, instant coffee, tea, meat products, dairy products, nut product, cereal product etc.
It is 10ppm, average maximum concentration 30-50ppm averagely to use depth.
Effect of the tea oil in terms of health has:Hair nursing, body care, scraping, foot lotion, soap, antimicrobial form are washed
Hand liquid, breath freshening net agent, oral care implement, first aid lotion, fungicide, burn nursing, antimycotic, mould, bacterio static itching-relieving
Deng.
In addition, the other application range of tea oil is also very extensive, (1) onychomycosis:It is directly instilled by finger tip webs, there is vertical pole
The benefits of seeing shadow.(2) it scalds:Upper several drops are directly dripped at scald, are wiped within about 2-3 hours once, collocation " aloe gel " effect is more preferable.
(3) it wounds, DOMS, slightly strain, arthritis, gout:It is crumpled on directly being dripped at swelling, can releive pain.(4) have a toothache,
Various focusing depths represented, corners of the mouth inflammation, thrush:It can directly spread, and coordinate toothpaste, dental floss, mouthwash, can be effectively improved, subtract
Light pain.(5) it has a stuffy nose, rhinitis:Directly smear under bridge of the nose both sides and nose, it is unimpeded at once after five minutes, there is the patient of rhinitis, directly
It is coated under nose with being coated in the position with rhinitis on a small quantity, then with some.But rhinitis had better take regular exercise, and avoid allergy
Source.(6) it catches cold:In the daytime healthy jasmine tea is continuously replenished, sleeps previous cup hot water+4 and drips essential oil, up to water cooling in a manner of compressing gas, then
It has a drink the careless tea of healthy jasmine tea.(7) blood from hemorrhoids:Directly wiping affected part can stop blooding.(8) it cures the wound:If diabetes patient's wound is not
Easily healing, please first wipes tea tree ethereal oil and adds medicine to again, you can improves, easily contracting wound.(9) mosquito-proof sting:10-15 drop essential oils+100CC
Water, spray whole body.Or few drops of tea tree ethereal oils are dripped in sunscreen or lotion and are smeared.(10) deodorant for refregerator:It is used to wring out
Tea bag+2-3 drop tea tree ethereal oil+2-3 drops, it is three-in-one to be placed in refrigerator.(11) it has a sore throat, cough, having phlegm, tonsillitis, branch gas
Guan Yan, asthma:Hot boiling water+the 3-4 of 200CC drip tea tree ethereal oil, with the hands open and are drawn onto until not having smell for flaring nare of shutting up, or are contained in mouth
It spues within middle about 20 seconds, symptom can get and releive.(12) eczema, diaper rash, dothienesis, acne, whelk:After face cleaning, a small amount of tea is taken
Tree essential oil pats affected part, rapid to improve.(13) serious scalp pruritus, dandruff:Shampoo+2-3 drop tea tree ethereal oil mixing hair washings,
Scalp is directly crumpled after hair washing again.(14) wet ear:Tea tree ethereal oil is stained with cotton rod directly to smear in what ear, several times rear ear humidity hair
Scorching phenomenon can improve.(15) virtue treats perfume:Fumigating light puts nine points of full water addend drop tea tree ethereal oils, can Antagonistic Environment bad cause
Son, while body and mind discomfort of releiving.(16) it baths:5-7 drops tea tree ethereal oil is dripped in bathtub or bathtub, steeps the bath warmed up.
The classification of borneol:Borneol is China's traditional Chinese medicine, is broadly divided into natural borneol and synthetic borneol.Natural borneol is main
It is the analysis of Spore density kapur resins or the crystallization (also referred to as Borneolum) that borneo camphor tree leaf is obtained by extraction purification, master
It is d-Bomeol to want chemical composition;Or the crystalline compounds that the blade of feverfew Blumea balsamifera is precipitated by means such as extractions
(also referred to as L-Borneol), main chemical compositions are L-Borneol.Natural borneol is less currently on the market, is mostly synthetic borneol.Synthesis
Borneol chemically synthesizes mainly with turpentine oil, camphor etc. for raw material.The main chemical compositions of synthetic borneol except borneol with
Outside, also contain a large amount of isoborneol (for the racemic modification of borneol).
The chemical composition of borneol:The main component of natural borneol is d-Bomeol, contains Humuleno, carypohyllene etc. simultaneously and exists
Interior a variety of sequiterpenes.In addition to sequiterpene, in natural borneol also contain oleanolic acid, alphitolic acid, etc. triterpenoids.Borneol
Effect (1) antibacterium, fungi effect, the borneol (0.5%) of higher concentration has a bacteriostasis, synthetic borneol and natural borneol
Bacteriostasis is identical, and borneol, isoborneol have antibacterial action.(2) anti-inflammatory and analgesic effect, borneol have swelling and pain relieving, anti-inflammatory, promotion
The effects that wound healing, is clinically usually used in treating burn and scald.
Currently, tea oil and borneol are applied in cosmetics, there are problems that poorly water-soluble, it is suitable to be now badly in need of finding
The composition for pressing down acne sterilization, has the skin of inflammation to have apparent inflammation-diminishing function, and can ensure the homogenieity of product.
Invention content
In order to overcome the problems, such as in the prior art, the present invention provides a kind of mild combinations with potent suppression acne sterilization
Object can prevent the long acne of skin commonly using this product, and have apparent repair function to the skin for having acne print acne to cheat.The present invention
Following technical scheme is provided:
A kind of composition of suppression acne sterilization, formula include following components count by weight percentage:
Further, formula includes following components count by weight percentage:
Further, in having the cosmetics finished product that the composition of the suppression acne sterilization is raw material production, borneol and tea
1% should be not less than by setting the content of oil.
Further, fusing point >=25 DEG C of the hard fat compound, spread out selected from fatty alcohol, aliphatic acid, fatty alcohol
One or two or more kinds of mixtures in biology, derivative of fatty acid.
Further, the emulsifier is nonionic emulsifier or anion breast of the hydrophilic and oleophilic HLB value between 8-15
One kind in agent or their mixture.
Further, the emollient is one or two or their mixing for being selected from following substance,
1) vegetable fat or hydrogenated vegetable fat;
2) polysiloxanes or methylpolysiloxane resin;
3) alkanes;
4) esters.
Further, the moisturizer is one or more mixed in polyalcohol, hyaluronic acid or its sodium salt, ceramide
Close object.
Further, the tea oil is refined by Taiwan high mountainous tea.
Further, stabilizer used is selected from one or more kinds of mixing:Xanthans, carragheen, acrylic acid
Polymer, acrylic acid/sodium acrylate polymer, acrylate copolymer, acrylate/C10-30 alkyl acrylates copolymerization
Object, acrylic acid/C10-30 alkyl acrylate copolymers, acrylic acid/acrylonitrile copolymer, acrylate/docosyl alcohol polyoxy second
Alkene ether metacrylic acid ester, acrylate/Brij-721 methacrylate copolymer, acrylate/aminopropan
Olefin(e) acid ester copolymer, acrylic copolymer/White Mineral Oil/tridecyl polyoxyethylene polyoxypropylene (6) polyethers, sodium acrylate copolymerization
Object/soybean oil/tridecyl polyoxypropylene (1) polyoxyethylene (6) polyethers, the derivative of acrylamide, alkene/alkylene oxide
The derivative of polymer, acrylamide.
Further, the composition contains:Fatty alcohol weight percent 4%, PEG-100 stearates and stearic acid are sweet
Glyceride mixtures weight percent 4%, carbonic acid dibutyl ester weight percent 14%, butanediol weight percent 12%, borneol weight
Measure percentage 0.5%, tea oil weight percent 0.8%, acrylate copolymer weight percent 0.2%, deionized water weight
Percentage 64.5%.
Further, the suppression acne bactericidal composition is applied to clear acne frost, clear acne cream, clear acne lotion, clear acne oils makeup
Product.
Using above-mentioned technical proposal, the present invention has the advantages that:
1, the composition of suppression acne of the invention sterilization can be used for clear acne frost, clear acne cream, clear acne lotion in skin care item.Tea oil
With bactericidal antiphlogistic, convergence pore, treatment cold, cough, rhinitis, asthma and other effects.Suitable for oiliness and acne-prone skin,
It treatment suppurative wound and burns, tan severely, athlete's foot and dandruff.It clears the head, rejuvenates, anti-depression is of the invention made
Clear pox cosmetic has the effect of good bactericidal antiphlogistic, maintenance.
2, tea tree ethereal oil is added, fat secretion is adjusted, promotes cytothesis, toxin expelling, oil extraction, improvement skin is coarse, desalination
The acne print left in the past, pockmark and acne recess hole, face pit repair all very acne prints, skin are allowed to take on an entirely new look.
3, tea tree ethereal oil and borneol are added, permeates skin bottom rapidly, anti-inflammation and sterilization keeps skin respiration channel unimpeded.It opens
Skin deep layer water source is opened, moisturizing water lock keeps moisture content power cycle, adjusts skin to water and oil balance state, eliminates small pox growth
Root.
Specific implementation mode
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to embodiment, to the present invention
It is further elaborated.It should be appreciated that described herein, specific examples are only used to explain the present invention, is not used to limit
The fixed present invention.
Embodiment 1
The present invention is a kind of mild composition with potent suppression acne sterilization, it is characterised in that:Count by weight percentage,
Formula includes following components:Hard fat compound 0.1-12.0%;Emulsifier 0.1-8%;Emollient 0.1-30.0%;It protects
Humectant 0.1-30.0%;Borneol 0.5-30%;Tea oil 0.2-30%;Stabilizer 0.1-10%;Surplus is deionized water.
Hard fat compound
Fatty compound can increase product consistency and skin care in the present invention.Fatty compound is in the present composition
Usage amount be 0.1-12%, preferably 1.0-9.0%, more preferably 3.0-6.0%.
Fusing point >=25 DEG C of hard fat compound are spread out selected from fatty alcohol, aliphatic acid, fatty alcohol derivative, aliphatic acid
One or two or more kinds of mixtures in biology.The hard fat compound for being best suited for the present invention is fatty alcohol, fat
The fusing point of alcohol is higher than 25 DEG C, and fatty alcohol of the invention most preferably has the fatty alcohol of 16 to about 22 carbon atoms, these fat
Fat alcohol is saturated fatty alcohol, and can be linear chain or branched chain alcohol.The non-limiting examples of fatty alcohol include cetanol, tristearin
The mixing of one or more of alcohol, docosyl alcohol.
Emulsifier
It is nonionic emulsifier or anion breast of the hydrophilic and oleophilic HLB value between 6-15 to be suitable for the invention emulsifier
A kind of or their mixing of agent, most preferred emulsifier are nonionic Emulsion of the hydrophilic and oleophilic HLB value between 10-14
A kind of or their mixing of agent or anion emulsifier.Preferable emulsifier is selected from glycoside, esters.
Glycoside is selected from coco group glucoside, cetyl glucoside, eicosyl glucoside, C12-20 alkyl glucosides
Glycosides.Esters are selected from C20-22 alkyl phosphates, tristerin, PEG-100 stearates, Sucrose Fatty Acid Ester.
Emollient
It is 0.1 to about 30.0% to be suitable for the invention emollient levels, most preferably 15-24%.Emollient has moist
It the effect of with soft skin, can be to prevent dry skin, dim, cracking.
Emollients vegetable oils fat or hydrogenated vegetable fat, such as:Apricot kernel oil, evening primrose oil, Sweet Almond Oil, rose hip oil, suddenly
Bar oil, wheat-germ oil, olive oil, carrot oil, castor oil, avocado oil, coconut oil, palm oil, cupu oil, cocoa butter, palm fibre suddenly
Palmitic acid benevolence oil, soybean oil, rice bran oil, aloe, mother-in-law sieve's fat, mowrah fat, sher butter, peanut oil, corn oil, Queensland nut
Oil, candlenut oil, Seabuckthorn Oil, linseed oil, passionflower caul-fat, pot marigold, mango kernel oil, cynarrhodion oil.
Emollient polysiloxanes or methylpolysiloxane resin.Including dimethyl siloxane and the poly- silicon of mixed aminomethyl phenyl
Oxygen alkane, resin can not be encroached on effective protection hair by extraneous harmful chemical, and polysiloxanes or methyl polysilicon oxygen
Alkane resin is a kind of gas permeability oil, can not only protect hair, but also can make hair eupnea and absorb nutriment, can be with
Lubrication hair and water resistant effect are provided.Emollient alkanes can be:Isomery dodecane, the isomery tetradecane, isomery hexadecane, angle
Shark alkane hydrogenates poly- certain herbaceous plants with big flowers alkene, dormant oil, vaseline etc.
Ester emollients are such as:Isopropyl palmitate, isobutyl palmitate, isopropyl myristate, isononyl isononanoate, firmly
Resin acid butyl ester, isopropyl isostearate, tridecyl trimellitate, three isopropyl ester of trimerized linoleic acid, propylene glycol isostearate, third
Glycol dicaprate, propylene, pentaerythritol stearate, isostearic acid butyl ester, carbonic acid dioctyl ester etc..
Moisturizer
Be suitable for the invention moisturizer be selected from polyalcohol, hyaluronic acid or its sodium salt, ceramide one kind or they
Mixing.Its polyalcohol dosage is between 0.1-30.0%, and preferable amount is between 2-20%, and most preferred quantities are in 10-15%
Between.The dosage of hyaluronic acid and its sodium salt and ceramide is in 0.1-10%, and most preferably weight is between 0.1-2%.These
Under certain condition, the moisture that can be absorbed in air plays moisture-keeping function to substance.Moisturizer can keep moisture, when being coated onto skin
Upper and skin close contact, can be transmitted to epidermis by moisture.Polyalcohol is such as:Propylene glycol, sorbierite, glycerine, 1.3 butanediols, two
Propylene glycol, methyl propanediol, molecular weight is in 2000 polyethylene glycol below, polyglycereol, maltitol, xylitol etc..Hyalomitome
Acid or its sodium salt are 1% aqueous solutions.
Tea oil
Camellia oil is suitable for the invention to be selected from:National Taiwan peasant undertaking area's sample platform gulf high mountainous tea.In recent years, Tianwan businessman
Alpineteafield in Zhangping popularizes tea tree in an all-round way and pours ' soya-bean milk ' technology, develops organic farming.By improveing soil, inhibiting disease
Bacterium extends the methods of tea picking period, effectively increases the yield and quality of tealeaves and tea seed.Its tea oil produced is rich in fat
Fat acid, camellin, Phospholipids, saponin(e, vitamin E, tannin etc. are at being grouped as.Its unsaturated fatty acid content is abundant, up to
93%., to skin have high moisturizing, moisten, maintenance the effect of, and it is natural pollution-free, be green product.Its dosage
Between 1.0-30%, preferred percent is in 5.0-20.0%, and most preferably percentage is between 7.0-15.0%.
Stabilizer
It is suitable for the invention stabilizer and is selected from one or more kinds of mixing:Xanthans, carragheen, acrylic acid are poly-
Close object, acrylic acid/sodium acrylate polymer, acrylate copolymer, acrylate/C10-30 alkyl acrylate copolymers,
Acrylic acid/C10-30 alkyl acrylate copolymers, acrylic acid/acrylonitrile copolymer, acrylate/docosyl alcohol polyoxyethylene
(25) ether metacrylic acid ester, acrylate/Brij-721 (20) methacrylate copolymer, acrylate/
Aminoacrylate copolymers, acrylic copolymer/White Mineral Oil/tridecyl polyoxypropylene (1) polyoxyethylene (6) polyethers, third
Olefin(e) acid sodium copolymer/soybean oil/tridecyl polyoxypropylene (1) polyoxyethylene (6) polyethers, the derivative of acrylamide, alkene/
Derivative (acrylamide copolymer compound, the acrylamide/sodium Acrylate copolymerization of alkylene oxide polymer, acrylamide
Object, alkene/alkylene oxide current limiting polymer, acid-thickened dose of Sal care SC 92, Sal care SC 95, Sal care
SC96 series.
Preferably, outer in the above formula, it is also possible to containing other ingredients, such as additive used in composition, preservative,
Fragrance, pigment, addition content is generally in 0.0-5%.
Plant extraction liquid, animal extracting solution can be selected.The mixing of one or more of biochemical product.Such as:Aloe,
Arnica, fragrant bee leaf, bigarabe, camomile, Chinese cassia tree, pseudo-ginseng, ginseng, gleditsia sinensis, ganoderma lucidum, burdock, lavender, cucumber, seaweed, rosemary
Equal plant extraction liquids, placenta extracting liquid, RHEGF, hydrolysis silk, royal jelly, propolis, vitamin e acetate, vitamin A palm
One kind of acid esters, niacinamide, vitamin B6, allantoin etc. or its mixing.The dosage of preservative is between 0.2-1.0%, such as hydroxyl
Benzene methyl, hydroxyl this propyl ester, ethyl hydroxy benzoate, butyl hydroxybenzoate, oxybenzene isobutyl ester, imidazolidinyl urea, chlormethylisothiazo,ine ketone, methyl
Isothiazolinone, iodo propinyl carbamate (IPBC), DMDM hydantoin, sodium benzoate, potassium sorbate one kind or its
Mixing.
In formula raw materials used and pigment and perfume ingredient all meet the 07 edition≤cosmetics health specification in China >=
Regulation.
Deionized water used in the present invention is to be purified twice by reverse osmosis and ion exchange resin, then pass through ultraviolet light
The pure water of sterilizing, conductivity are less than 0.5 μ s/cm.
Preferably, the formula of present invention suppression acne bactericidal composition is:Fatty alcohol weight percent 4%, PEG-100 stearic acid
Ester and glyceryl stearate mixture weight percent 4%, carbonic acid dibutyl ester weight percent 14%, butanediol weight percent
12%, borneol weight percent 0.5%, tea oil weight percent 0.8%, acrylate copolymer weight percent 0.2%, go
Ionized water weight percent 64.5%.
Embodiment 2
To be expanded on further and illustrating that the various embodiments in the scope of the invention, institute are only illustrative to example
, it is not intended to limit the present invention, because without departing from the spirit and scope of the present invention, can be carried out to the present invention
A variety of changes, unless stated otherwise, following raw materials according title all presses the material name of INCI names or its trade name is write.Raw material
Percentage all refer to weight percent, ratio is all based on the pure content of ingredient.
The clear acne frost of comparative example and embodiment is all fabricated by following process in table one, and wherein step 5 is preferred step
Suddenly.
It is all molten to 90 DEG C -95 DEG C to raw material that A is added to the warming while stirring in a suitable container by step 1
Solution;
It is all molten to 90 DEG C -95 DEG C to raw material that B is added to the warming while stirring in a suitable container by step 2
Solution;
Step 3 is slowly added into B phases in A phases while stirring, stirs 2 minutes, homogeneous 5 minutes, and mixing speed control exists
20r/m homogeneous speed is 1400-2600r/m, and homogenizing temperature is controlled at 80-90 DEG C;It is stirred 5 minutes after homogeneous and starts to cool down.
C phases are added when 50 DEG C of step 4;
40 DEG C of step 5 is that D phases are added, and continues to be stirred to 35-38 DEG C of discharging.
By with cold cycling method to carrying out one month tracing detection with the product of the above technique productions, it was demonstrated that the formula
It is stable, technique is feasible.
Table one is each experimental group and the formulation content of control group, as shown in Table 1.
Table one
Clear acne frost measure of merit, looks for the volunteer of face or the long acne of skin of back totally 30 people, one group of every 5 people, totally six components
Not Shi Yong experimental group and control group totally six products, be used continuously 10 days, be further continued for tracking 5 days, existed daily by 8 skin experts
Using being evaluated its skin before clear acne frost, every group takes its average value, as a result summarizes as (wherein 0-10 refers to skin to table 2
Health index, index is higher, and skin is more healthy).
Table 2
Find out from the experimental data of table 2 and uses the clear acne frost containing 0.3%, 0.5%, 0.6%, 0.8% tea oil respectively
There is good repair to the skin of long acne, and the clear acne frost without tea oil acts on true very little to the skin repair of long acne.
It can also be seen that the clear acne frost of the tea oil containing 0.6-0.8% improves 2-4 than effect of the clear acne frost of 0.1% tea oil from table
Again, 3-5 times is improved than the effect of common face cream without tea oil.It can also find out containing 0.5% borneol and 0.8% tea from table
The clear acne frost fungistatic effect for setting oil is best, and the clear acne frost fungistatic effect containing 0.4% borneol and 0.6% tea oil takes second place.
Embodiments of the present invention above described embodiment only expresses, the description thereof is more specific and detailed, but can not
Therefore it is interpreted as the limitation to the scope of the claims of the present invention.It should be pointed out that for those of ordinary skill in the art,
Without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to the protection model of the present invention
It encloses.Therefore, the protection domain of patent of the present invention should be determined by the appended claims.
Claims (11)
1. a kind of composition of suppression acne sterilization, which is characterized in that it includes following components count by weight percentage that it, which is formulated,:
2. the composition of suppression acne sterilization according to claim 1, which is characterized in that its formula wraps count by weight percentage
Include following components:
3. the composition of suppression acne sterilization according to claim 1, which is characterized in that in the composition for having the suppression acne sterilization
In cosmetics finished product for raw material production, the content of borneol and tea oil should be not less than 1%.
4. the composition of suppression acne sterilization according to claim 1, it is characterised in that:The hard fat compound melts
Point >=25 DEG C, one or two or more kinds of mixing in fatty alcohol, aliphatic acid, fatty alcohol derivative, derivative of fatty acid
Object.
5. the composition of suppression acne sterilization according to claim 1, it is characterised in that:The emulsifier is hydrophilic and oleophilic HLB
One kind or their mixture being worth in the nonionic emulsifier or anion emulsifier between 8-15.
6. the composition of suppression acne sterilization according to claim 1, it is characterised in that:The emollient is to be selected from following substance
One or two or their mixing,
1) vegetable fat or hydrogenated vegetable fat;
2) polysiloxanes or methylpolysiloxane resin;
3) alkanes;
4) esters.
7. the composition of suppression acne sterilization according to claim 1, it is characterised in that:The moisturizer is polyalcohol, transparent
One or more mixtures in matter acid or its sodium salt, ceramide.
8. the mild composition of potent suppression acne sterilization according to claim 1, it is characterised in that:The tea oil is by platform
Gulf high mountainous tea refines.
9. the composition of suppression acne sterilization according to claim 1, it is characterised in that:Stabilizer used is selected from a kind of
Or two or more mixing:Xanthans, carragheen, acrylate copolymer, acrylic acid/sodium acrylate polymer, acrylic ester copolymer
Object, acrylate/C10-30 alkyl acrylate copolymers, acrylic acid/C10-30 alkyl acrylate copolymers, acrylic acid/
Acrylonitrile copolymer, acrylate/docosyl alcohol polyethenoxy ether metacrylic acid ester, acrylate/Brij-721
Methacrylate copolymer, acrylate/aminoacrylate copolymers, acrylic copolymer/White Mineral Oil/tridecyl are poly-
Oxypropylene polyoxyethylene (6) polyethers, sodium acrylate copolymer/soybean oil/tridecyl polyoxypropylene (1) polyoxyethylene (6) are poly-
The derivative of ether, the derivative of acrylamide, alkene/alkylene oxide polymer, acrylamide.
10. the composition of the suppression acne sterilization according to any one of claim 4-9, it is characterised in that:The composition contains
Have:Fatty alcohol weight percent 4%, PEG-100 stearates and glyceryl stearate mixture weight percent 4%, carbonic acid
Dibutyl ester weight percent 14%, butanediol weight percent 12%, borneol weight percent 0.5%, tea oil weight percent
Number 0.8%, acrylate copolymer weight percent 0.2%, deionized water weight percentage 64.5%.
11. the composition of suppression acne sterilization according to claim 1, which is characterized in that the suppression acne bactericidal composition application
In clear acne frost, clear acne cream, clear acne lotion, clear acne oils cosmetics.
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| CN201810564359.XA CN108553341A (en) | 2018-06-04 | 2018-06-04 | A kind of composition of suppression acne sterilization |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810564359.XA CN108553341A (en) | 2018-06-04 | 2018-06-04 | A kind of composition of suppression acne sterilization |
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| CN108553341A true CN108553341A (en) | 2018-09-21 |
Family
ID=63552796
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| CN201810564359.XA Pending CN108553341A (en) | 2018-06-04 | 2018-06-04 | A kind of composition of suppression acne sterilization |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110403893A (en) * | 2019-08-06 | 2019-11-05 | 江苏蜂奥生物科技有限公司 | A kind of mildy wash containing propolis extract |
| CN110721127A (en) * | 2019-10-21 | 2020-01-24 | 洛阳宁邦生物制药有限公司 | Acne-removing lotion and preparation method thereof |
| CN114159346A (en) * | 2020-09-10 | 2022-03-11 | 美黛(上海)生物科技有限公司 | Bacteriostatic composition for daily life and preparation method thereof |
| CN114796113A (en) * | 2022-01-06 | 2022-07-29 | 贵州大学 | Application of blumea balsamifera oil nanoemulsion in preparation of anti-tumor drugs and wound repair drugs |
| CN116831928A (en) * | 2023-08-24 | 2023-10-03 | 新晃县九州农业综合开发有限公司 | Propionibacterium acnes-inhibiting composition containing natural borneol and application of composition in cosmetics |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104906006A (en) * | 2015-06-23 | 2015-09-16 | 蔡锦瑜 | Cleaning mask |
| CN105779175A (en) * | 2016-04-06 | 2016-07-20 | 江苏耐雀生物工程技术有限公司 | Natural handmade soap with acne removing function and preparation method of natural handmade soap |
-
2018
- 2018-06-04 CN CN201810564359.XA patent/CN108553341A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104906006A (en) * | 2015-06-23 | 2015-09-16 | 蔡锦瑜 | Cleaning mask |
| CN105779175A (en) * | 2016-04-06 | 2016-07-20 | 江苏耐雀生物工程技术有限公司 | Natural handmade soap with acne removing function and preparation method of natural handmade soap |
Non-Patent Citations (1)
| Title |
|---|
| 广州市碧莹化妆品有限公司: "战辉茶树油清痘霜(加强型)", 《HTTP://FTBA.NMPA.GOV.CN:8181/FTBAN/ITOWNET/HZP_BA/FW/PZ.JSP?PROCESSID=201511061216202PLNA&NID=201511061216202PLNA》 * |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110403893A (en) * | 2019-08-06 | 2019-11-05 | 江苏蜂奥生物科技有限公司 | A kind of mildy wash containing propolis extract |
| CN110721127A (en) * | 2019-10-21 | 2020-01-24 | 洛阳宁邦生物制药有限公司 | Acne-removing lotion and preparation method thereof |
| CN114159346A (en) * | 2020-09-10 | 2022-03-11 | 美黛(上海)生物科技有限公司 | Bacteriostatic composition for daily life and preparation method thereof |
| CN114796113A (en) * | 2022-01-06 | 2022-07-29 | 贵州大学 | Application of blumea balsamifera oil nanoemulsion in preparation of anti-tumor drugs and wound repair drugs |
| CN114796113B (en) * | 2022-01-06 | 2023-05-30 | 贵州大学 | Application of a kind of Aina sesame oil nanoemulsion in the preparation of antitumor drugs and wound repair drugs |
| CN116831928A (en) * | 2023-08-24 | 2023-10-03 | 新晃县九州农业综合开发有限公司 | Propionibacterium acnes-inhibiting composition containing natural borneol and application of composition in cosmetics |
| CN116831928B (en) * | 2023-08-24 | 2024-06-18 | 新晃县九州农业综合开发有限公司 | Propionibacterium acnes-inhibiting composition containing natural borneol and application of composition in cosmetics |
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