CN109932520A - Blood test device - Google Patents
Blood test device Download PDFInfo
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- CN109932520A CN109932520A CN201910319419.6A CN201910319419A CN109932520A CN 109932520 A CN109932520 A CN 109932520A CN 201910319419 A CN201910319419 A CN 201910319419A CN 109932520 A CN109932520 A CN 109932520A
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Abstract
The invention discloses a kind of blood test device, which includes blood routine detection unit and SAA detection unit；The blood routine detection unit includes sampling needle and counting cell unit, and the SAA detection unit includes the pond SAA；The sampling needle is for drawing and distributing blood sample to the counting cell unit and the pond SAA；The counting cell unit is used to carry out the blood sample of distribution the measurement of blood routine parameter, and the pond SAA measures SAA parameter as dilution, the reaction vessel of SAA reagent and blood sample.The present invention can detect SAA and blood routine simultaneously, and realization automatic measurement blood routine parameter and SAA parameter on an instrument with a venous whole improve hospital outpatient efficiency to provide more fully diagnostic data in lower cost and shorter time for inflammation.
Description
Technical field
The present invention relates to the field of medical instrument technology more particularly to a kind of blood test devices.
Background technique
In clinic, being frequently run onto some patients' needs while detecting blood routine and certain Special Proteins to diagnose the patient is
It is no since bacterium or virus infection bring slight illness, the detection of Special Proteins generally comprises CRP, and (C-reactionprotein, C are anti-
Answer albumen) measurement and SAA (serum amyloid A protein) measurement, blood routine detection and blood in Special Proteins detection due to
Using different detection methods, so being completed by different instruments.
Due to detect different types of haemocyte or Special Proteins, it is therefore desirable to which purchasing different detecting instruments could be complete
At detection, the equipment input cost that is bound to is high, inconvenient.
Summary of the invention
The main object of the present invention is to provide a kind of blood test device, it is intended to solve detection device function in the prior art
Single and inconvenient technical problem.
To achieve the above object, blood test device proposed by the present invention includes that blood routine detection unit and SAA detection are single
Member；The blood routine detection unit includes sampling needle and counting cell unit, and the SAA detection unit includes the pond SAA；The sampling
Needle is for drawing and distributing blood sample to the counting cell unit and the pond SAA；The counting cell unit is used for the blood to distribution
Sample carries out the measurement of blood routine parameter, and the pond SAA is measured as dilution, the reaction vessel of SAA reagent and blood sample
SAA parameter.
Preferably, the blood test device further includes CRP detection unit, and the CRP detection unit includes the pond CRP；Institute
It states sampling needle and is also used to draw and distribute blood sample to the pond CRP, the pond CRP is anti-as dilution, CRP reagent and blood sample
Container is answered, and measures CRP parameter.
Preferably, the blood routine detection unit further includes DIFF channel measurement unit, syringe unit, dilution point
With unit and negative pressure chamber；The counting cell unit includes the pond DIFF, the pond WBC, the pond RBC, and the pond DIFF is as dilution, DIFF
The reaction vessel of reagent and blood sample, the pond WBC are used as dilution, the reaction vessel of WBC reagent and blood sample, the pond RBC
It is counted in carrying out RBC and PLT；The dilution allocation unit connects the pond SAA, the pond CRP, the pond DIFF, the pond WBC and the pond RBC；
The syringe unit via the dilution allocation unit for distributing dilution to the pond SAA, the pond CRP, the pond DIFF, WBC
Pond and the pond RBC；The syringe unit is also used to SAA reagent being assigned to the pond SAA, CRP reagent is assigned to the CRP
WBC reagent is assigned to the pond WBC by pond；DIFF reagent is assigned to the pond DIFF；The DIFF lane testing unit is used
In the classification of leucocyte；The negative pressure chamber provides sample flow driving force for the pond WBC and the pond RBC.
Preferably, the counting cell unit includes the pond DIFF, and the pond DIFF is provided with DIFF reagent inlet, the DIFF
Reagent inlet one and only one, the sampling needle is also used to draw and distribute blood sample to the pond DIFF, the pond the DIFF work
For dilution, the reaction vessel of DIFF reagent and blood sample.
Preferably, the blood test device further includes CRP detection unit, and the CRP detection unit includes the pond CRP；Institute
It states sampling needle and is also used to draw and distribute blood sample to the pond CRP, the pond CRP is anti-as dilution, CRP reagent and blood sample
Container is answered, and measures CRP parameter.
Preferably, the blood routine detection unit further includes DIFF channel measurement unit, syringe unit, dilution distribution
Unit, negative pressure chamber；The counting cell unit further includes the pond WBC, the pond RBC, and the pond WBC is as dilution, WBC reagent and blood sample
Reaction vessel, the pond RBC is counted for carrying out RBC and PLT；The dilution allocation unit connects the pond SAA, CRP
Pond, the pond DIFF, the pond WBC and the pond RBC；The syringe unit be used for by dilution via the dilution allocation unit distribute to
The pond SAA, the pond CRP, the pond DIFF, the pond WBC and the pond RBC；The syringe unit be also used to for SAA reagent being assigned to the pond SAA,
CRP reagent is assigned to the pond CRP, WBC reagent is assigned to the pond WBC；DIFF reagent is assigned to the pond DIFF；
The DIFF lane testing unit is used for the classification of leucocyte；The negative pressure chamber provides sample for the pond WBC and the pond RBC
Flow driving force.
Preferably, the pond SAA includes SAA pond body, second laser and the second photodetector, the SAA pond body
Mouth, SAA waste liquid outlet is added with SAA reagent；The second laser and second photodetector are in SAA pond body
SAA measurement of concetration.
Preferably, the pond CRP includes CRP pond body, third laser and third photodetector, the CRP pond body
Mouth, CRP waste liquid outlet is added with CRP reagent；The third laser and the third photodetector are in CRP pond body
CRP measurement of concetration.
Preferably, the DIFF channel measurement unit includes first laser device, the first photodetector and flow chamber, described
First laser device and first photodetector are respectively arranged on the opposite sides along sample flow direction of the flow chamber；?
Under the syringe unit effect, sample flow passes through the flow chamber, the first laser device and first photodetector
The classification of leucocyte is completed in cooperation.
Preferably, the pond WBC and the pond RBC have respectively included impedance measuring unit, each impedance measurement list
Member includes forebay electrode, gem hole, after-bay electrode；The negative pressure of cell in the pond WBC and the pond RBC in the negative pressure chamber
One by one by the gem hole under effect, when cell passes through the gem hole, the forebay electrode can be produced with the after-bay electrode
Raw pulse, calculates WBC quantity, RBC quantity and PLT quantity according to number of pulses.
Preferably, the pond WBC further includes HGB measuring unit, and the HGB measuring unit includes light emitting diode and photoelectricity
Receiver, the light that the light emitting diode issues is transmitted to the photelectric receiver by the reaction solution in the pond WBC, according to described
The transmitted intensity that photelectric receiver receives calculates HGB concentration.
Preferably, the blood routine detection unit further includes refrigeration unit, and the refrigeration unit is used for the SAA reagent
It controls with the CRP temperature of reagent at 2-8 DEG C.
Preferably, the blood routine detection unit further includes preheating unit, and the preheating unit tries the SAA
Agent, CRP reagent, DIFF reagent and dilution are preheated before being added to each reaction tank.
Preferably, the blood routine detection unit further includes syringe unit, dilution allocation unit and negative pressure chamber；It is described
Counting cell unit includes the pond WBC, the pond RBC, and the pond WBC is as dilution, the reaction vessel of WBC reagent and blood sample, the RBC
Pond is counted for carrying out RBC and PLT；The dilution allocation unit connects the pond SAA, the pond WBC and the pond RBC；The injection
Device unit via the dilution allocation unit for distributing dilution to the pond SAA, the pond WBC and the pond RBC；The syringe list
Member is also used to for SAA reagent to be assigned to the pond SAA, WBC reagent is assigned to the pond WBC；The negative pressure chamber is the WBC
Pond and the pond RBC provide sample flow driving force.
Preferably, the blood routine detection unit does not include the pond DIFF and DIFF lane testing unit.
Preferably, the blood routine detection unit further includes the pond DIFF and DIFF lane testing unit, and the pond DIFF is made
For dilution, the reaction vessel of DIFF reagent and blood sample, the dilution allocation unit connects the pond DIFF, the syringe
For distributing dilution via the dilution allocation unit to the pond DIFF, the syringe unit is also used to DIFF unit
Reagent is assigned to the pond DIFF, and the DIFF lane testing unit is used for the classification of leucocyte.
Preferably, the pond SAA includes SAA pond body, second laser and the second photodetector, the SAA pond body
Mouth, SAA waste liquid outlet is added with SAA reagent；The second laser and second photodetector are in SAA pond body
SAA measurement of concetration.
Blood test device proposed by the present invention can do the measurement of blood routine and the measurement of SAA simultaneously, can be lower
Blood routine and the testing result of SAA are obtained in cost and shorter time, provide more fully diagnostic data for inflammation；It realizes with one
Branch venous whole on an instrument simultaneously automatic measurement blood routine parameter and SAA parameter, reduce measurement cost improve simultaneously
The convenience of the above parameter measurement, to improve hospital outpatient efficiency.
Detailed description of the invention
In order to more clearly explain the embodiment of the invention or the technical proposal in the existing technology, to embodiment or will show below
There is attached drawing needed in technical description to be briefly described, it should be apparent that, the accompanying drawings in the following description is only this
Some embodiments of invention for those of ordinary skill in the art without creative efforts, can be with
The structure shown according to these attached drawings obtains other attached drawings.
Fig. 1 is the whole theory structure schematic diagram of blood test device embodiment one of the present invention；
Fig. 2 is the structural schematic diagram of dilution allocation unit in blood test device embodiment one of the present invention；
Fig. 3 is the structural schematic diagram in the pond DIFF in blood test device embodiment one of the present invention；
Fig. 4 is the theory structure schematic diagram of DIFF channel measurement unit in blood test device embodiment one of the present invention；
Fig. 5 is the theory structure schematic diagram of one middle impedance measuring unit of blood test device embodiment of the present invention；
Fig. 6 is the theory structure schematic diagram of HGB measuring unit in blood test device embodiment one of the present invention；
Fig. 7 is the structural schematic diagram in the pond SAA in blood test device embodiment one of the present invention；
Fig. 8 is the whole theory structure schematic diagram of blood test device embodiment two of the present invention；
Fig. 9 is the structural schematic diagram of dilution allocation unit in blood test device embodiment two of the present invention；
Figure 10 is the structural schematic diagram in the pond CRP in blood test device embodiment two of the present invention；
Figure 11 is the flow diagram of the blood testing of blood test device of the present invention.
Drawing reference numeral explanation:
The embodiments will be further described with reference to the accompanying drawings for the realization, the function and the advantages of the object of the present invention.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete
Site preparation description, it is clear that described embodiment is only a part of the embodiments of the present invention, instead of all the embodiments.Base
Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts it is all its
His embodiment, shall fall within the protection scope of the present invention.
It is to be appreciated that the directional instruction (such as up, down, left, right, before and after ...) of institute is only used in the embodiment of the present invention
In explaining in relative positional relationship, the motion conditions etc. under a certain particular pose (as shown in the picture) between each component, if should
When particular pose changes, then directionality instruction also correspondingly changes correspondingly.
In addition, the description for being such as related to " first ", " second " in the present invention is used for description purposes only, and should not be understood as
Its relative importance of indication or suggestion or the quantity for implicitly indicating indicated technical characteristic.Define as a result, " first ",
The feature of " second " can explicitly or implicitly include at least one of the features.In the description of the present invention, " multiple " contain
Justice is at least two, such as two, three etc., unless otherwise specifically defined.
In the present invention unless specifically defined or limited otherwise, term " connection ", " fixation " etc. shall be understood in a broad sense,
For example, " fixation " may be a fixed connection, it may be a detachable connection, or integral；It can be mechanical connection, be also possible to
Electrical connection；It can be directly connected, the connection inside two elements or two can also be can be indirectly connected through an intermediary
The interaction relationship of a element, unless otherwise restricted clearly.It for the ordinary skill in the art, can basis
Concrete condition understands the concrete meaning of above-mentioned term in the present invention.
It in addition, the technical solution between each embodiment of the present invention can be combined with each other, but must be general with this field
Based on logical technical staff can be realized, it will be understood that when the combination of technical solution appearance is conflicting or cannot achieve this
The combination of technical solution is not present, also not the present invention claims protection scope within.
The present invention proposes a kind of blood test device.
Referring to Fig. 1, in embodiments of the present invention, which includes blood routine detection unit 100 and SAA
(serum amyloid A protein) detection unit 200；The blood routine detection unit 100 includes sampling needle 10 and counting cell unit 30,
The SAA detection unit 200 includes the pond SAA 31；The sampling needle 10 is for drawing and distributing blood sample to the counting cell unit
30 and the pond SAA 31；The counting cell unit 30 is used to carry out the blood sample of distribution the measurement of blood routine parameter, the SAA
Pond 31 measures SAA parameter as dilution 25, the reaction vessel of SAA reagent 23 and blood sample.
Blood test device proposed by the present invention can do the measurement of blood routine and the measurement of SAA simultaneously, can be lower
Blood routine and the testing result of SAA are obtained in cost and shorter time, provide more fully diagnostic data for inflammation；It realizes with one
Branch venous whole on an instrument simultaneously automatic measurement blood routine parameter and SAA parameter, reduce measurement cost improve simultaneously
The convenience of the above parameter measurement, to improve hospital outpatient efficiency.This is also some anaemias for needing to do blood testing simultaneously
Patient or the patient of other anaematopoiesis bring convenience, they only need to extract a pipe blood when doing blood testing
Sample goes different detecting instruments to detect without extracting multitube blood sample again.
Embodiment one:
Specifically, referring to Fig. 1, the blood routine detection unit 100 further includes reagent unit 20, syringe unit
40, dilution allocation unit 50, DIFF (Differential, classification) channel measurement unit 325, negative pressure chamber 60 and discharging of waste liquid
Unit 70；
The reagent unit 20 includes: dilution 25, WBC (White Blood Cell, leucocyte) reagent 21, DIFF examination
Agent 22, SAA reagent 23；
The counting cell unit 30 includes: the pond DIFF 32, the pond WBC 33, RBC (Red Blood Cell, red blood cell) pond 34；
The pond DIFF 32 as dilution 25, the reaction vessel of DIFF reagent 22 and blood sample, the pond WBC 33 as dilution 25,
The reaction vessel of WBC reagent 21 and blood sample, the pond RBC 34 are counted for carrying out RBC and PLT (Platelet, blood platelet)；
The sampling needle 10 is for drawing and distributing blood sample to the pond SAA 31, the pond DIFF 32, the pond WBC 33, the pond RBC 34；
The dilution allocation unit 50 connects the pond SAA 31, the pond DIFF 32, the pond WBC 33 and the pond RBC 34；The note
Emitter unit 40 is used to via the dilution allocation unit 50 distribute dilution 25 to the pond SAA 31, the pond DIFF 32, the pond WBC
The pond 33 and RBC 34；The syringe unit 40 is also used to SAA reagent 23 being assigned to the pond SAA 31, divides WBC reagent 21
It is fitted on the pond WBC 33；DIFF reagent 22 is assigned to the pond DIFF 32；
The DIFF lane testing unit 325 is used for the classification of leucocyte；
The negative pressure chamber 60 provides sample flow driving force with the pond RBC34 for the pond WBC 33；
The discharging of waste liquid unit 70 is used for the discharge of complete machine waste liquid.Since the discharge of pharmaceutical reagent will meet industry mark
Standard, therefore increase discharging of waste liquid unit 70.But for instrument and equipment, discharging of waste liquid unit 70 is also possible to be arranged to be set at other
Standby upper component, or extraneous individual component.
Specifically, the syringe unit 40 include the first syringe 41, the second syringe 42, third syringe 43 and
4th syringe 44；First syringe 41 connects the dilution allocation unit 50, mentions for the distribution of the dilution 25
For power；Second syringe 42 connects the DIFF channel measurement unit 325, for the channel DIFF sample flow provide it is dynamic
Power；The third syringe 43 drags three syringes for one, and one of syringe connects the suction that the sampling needle 10 carries out blood sample
Take and inject, other two syringe is separately connected the pond WBC 33 and the pond DIFF 32, and cooperate the first triple valve 331,
The WBC reagent 21 and the DIFF reagent 22 are separately dispensed into the pond WBC 33 and the pond DIFF by the second triple valve 321
32；4th syringe 44 is one drag two syringe, and the SAA reagent 23 includes that the first SAA reagent 231 and the 2nd SAA are tried
Agent 232, the 4th syringe 44 connect the pond SAA 31, and third triple valve 315, the 4th triple valve 316 is cooperated respectively will
The first SAA reagent 231 and the 2nd SAA reagent 232 are assigned to the pond SAA 31.
Specifically, referring to Figure 2 together, the dilution allocation unit 50 includes liquid storage tank 51, the 7th triple valve 52, the
Eight triple valves 53, the 9th triple valve 54 and the tenth triple valve 55；The liquid storage tank 51 is described for storing the dilution 25
Dilution 25 is added respectively by the 7th triple valve 52, the 8th triple valve 53, the 9th triple valve 54 and the tenth triple valve 55
Enter to the pond SAA 31, the pond DIFF 32, the pond WBC 33, the pond RBC 34.
Specifically, also referring to Fig. 3, the pond DIFF 32 be provided with DIFF reagent inlet 322, sample exit port 323 with
And DIFF waste liquid outlet 324, the DIFF reagent inlet 322 one and only one, the DIFF reagent inlet 322 connects described
Third syringe 43 and DIFF reagent 22, the sample exit port 323 connect the DIFF channel measurement unit 325, the DIFF
Waste liquid outlet 324 connects the discharging of waste liquid unit 70.Its DIFF channel measurement only needs to reduce using a kind of DIFF reagent 22
Reagent use cost and instrument cost.
Specifically, referring to Figure 4 together, the DIFF channel measurement unit 325 includes first laser device 3251, the first light
Electric explorer 3252 and flow chamber 3253, the first laser device 3251 are respectively arranged on institute with first photodetector 3252
State the opposite sides along sample flow direction of flow chamber 3253；In second syringe 42 and the third syringe 43
Under collective effect, sample flow passes through the flow chamber 3253, the first laser device 3251 and first photodetector
The measurement in the channel DIFF is completed in 3252 cooperations.Its specific measurement process is to handle in haemocyte by dilution 25 and hemolytic agent
Flow chamber 3253 is flowed through to leucocyte to be measured, the sheath fluid 3255 of certain speed is added in 3254 two sides of leucocyte channel, when white
When cell is flowed through at 3251 irradiation of first laser device, two kinds of scattering light of the low angle angle of elevation, first photodetector are produced
3252 can receive scattered light signal.Wherein low angle scattering light is related with cell size, and high angle scatter light and cell interior are fine
Structure is related with particle, to realize blood cell differential.
Specifically, please refer to fig. 5, the pond WBC 33 and the pond RBC 34 include impedance measuring unit 332, institute
Stating impedance measuring unit 332 includes forebay electrode 333, gem hole 334, after-bay electrode 335；The pond WBC 33 and the pond RBC
Cell in 34, one by one by the gem hole 334, is put under the suction function of the negative pressure chamber 60 at the both ends of gem hole 334
A pair can provide the forebay electrode 333 and after-bay electrode 335 of constant current, when in sample cell or blood platelet flow through gem hole
When 334, the D.C. resistance between two electrodes can change, and the voltage at electrode both ends can also change at this time, will form
Pulse relevant to cellular morphology, the number of pulse are exactly the number of cell, and the size of pulse amplitude represents cell amplitude
Size, so as to calculate WBC quantity, RBC quantity and PLT quantity.
Further, referring to Fig. 6, the pond WBC 33 further includes HGB (Hemoglobin, hemoglobin) measuring unit
336, the HGB measuring unit 336 includes light emitting diode 337 and photelectric receiver 338；Sample passes through hemolytic agent in measurement
Afterwards, red blood cell is dissolved, HGB is reacted with hemolytic agent, forms haemoglobin complexes, there is specific wavelength in the one end in the pond WBC 33
Light emitting diode 337, other side photelectric receiver 338 carry out photoelectric conversion to transmitted light and obtain voltage signal；It allows first only
The sample of dilution 25 enters the pond WBC 33, measures a background voltage, and sample is then entered the pond WBC 33 and obtains sample at this time
Voltage, wherein hemoglobin concentration is bigger, and the translucency of reactant is poorer, and the voltage value of photoelectric conversion is lower, so as to
Calculate HGB concentration.
Specifically, referring to Fig. 7, the pond SAA 31 includes SAA pond body 311, second laser 318 and the second photoelectricity
There is SAA reagent mouth 312, SAA waste liquid outlet 317 is added for detector 319, the SAA pond body 311, and mouth is added in the SAA reagent
312 include that mouth 313 and the 2nd SAA reagent addition mouth 314 is added in the first SAA reagent；The second laser 318 and described second
Photodetector 319 is separately positioned on 311 two sides of SAA pond body.When blood sample, the first SAA reagent 231 and the 2nd SAA reagent
232, which are added separately in SAA pond body 311 rear solution, starts to react, and insoluble compound occurs, when second laser 318 issues
Light scatter when passing through insoluble compound, scattered light intensity and SAA concentration have certain proportionate relationship, pass through second
The scattered light intensity that photodetector 319 receives can calculate SAA concentration.
Embodiment two:
Fig. 8 and Fig. 9 are please referred to, the second embodiment of the present invention is identical with the first embodiment substantially, and difference is: the blood
Liquid detection device further includes CRP detection unit 300, and the CRP detection unit 300 includes CRP (C-reactionprotein, C
Reactive protein) pond 35, reagent unit 20 further includes CRP reagent 24, and the CRP reagent 24 includes the first CRP reagent 241 and second
CRP reagent 242；For the sampling needle 10 for drawing and distributing blood sample to the pond CRP 35, the pond CRP 35 is used as dilution
25, the reaction vessel of CRP reagent 24 and blood sample, and measure CRP parameter；4th syringe 44 is one to drag four syringes, the 4th
Syringe 44 connects the pond SAA 31 and the pond CRP 35, and third triple valve 315, the 4th triple valve 316 is cooperated respectively will
The first SAA reagent 231 and the 2nd SAA reagent 232 are assigned to the pond SAA 31, cooperate the 5th triple valve the 355, the 6th 3
The first CRP reagent 241 and the 2nd CRP reagent 242 are assigned to the pond CRP 35 respectively by port valve 356；Dilution distribution is single
Member 50 further includes the 11st triple valve 56, and the dilution 25 is added to the pond CRP 35 by the 11st triple valve 56.
Specifically, also referring to Figure 10, the pond CRP 35 includes CRP pond body 351, third laser 358 and third
There is CRP reagent mouth 352, CRP waste liquid outlet 357 is added for photodetector 359, the CRP pond body 351；The CRP reagent adds
Entrance 352 includes that mouth 353 and the 2nd CRP reagent addition mouth 354 is added in the first CRP reagent；The third laser 358 with it is described
Third photodetector 359 is separately positioned on 351 two sides of CRP pond body.As blood sample, the first CRP reagent 241 and the 2nd CRP
Solution starts to react after reagent 242 is added separately in CRP pond body 351, insoluble compound occurs, when third laser 358
The light of sending scatters when passing through insoluble compound, and scattered light intensity and CRP concentration have certain proportionate relationship, passes through
The scattered light intensity that third photodetector 359 receives can calculate CRP concentration.
Embodiment three:
The third embodiment of the present invention is identical with the first embodiment substantially, and difference is: the blood routine detection unit is not
Including the pond DIFF 32, DIFF lane testing unit 325 and DIFF reagent 22.
Based on above three embodiments, the blood test device further includes refrigeration unit 80 and preheating unit 90, institute
Refrigeration unit 80 is stated for the first CRP reagent 241 and the control of 231 temperature of the first SAA reagent at 2-8 DEG C, to be guaranteed reagent
Validity.The preheating unit 90 be used for the first CRP reagent 241, the 2nd CRP reagent 242, the first SAA reagent 231,
2nd SAA reagent 232, dilution 25 and DIFF reagent 22 are preheated, and the reaction of each reaction tank is accelerated, and improve measurement effect
Rate.
Figure 11 is please referred to, above-mentioned blood test device is based on, the present invention provides a kind of blood testing, specific method stream
Journey is as follows:
Step S1: sampling needle 10 draws whole blood sample；
Step S2: sampling needle 10 is moved to 35 position of the pond CRP, injects appropriate blood sample, while the 4th syringe 44 will pass through
Preheating CRP reagent 24 is injected in the pond CRP 35 and is reacted；
Step S3: sampling needle 10 is moved to 31 position of the pond SAA, injects appropriate blood sample, while the 4th syringe 44 will pass through
Preheating SAA reagent 23 is injected in the pond SAA 31 and is reacted；
Step S4: sampling needle 10 is moved to 32 position of the pond DIFF, injects appropriate blood sample, while third syringe 43 will pass through
Preheating DIFF reagent 22 is injected in the pond DIFF 32 and is reacted；
Appropriate dilution 25 is injected in the pond step S5:WBC 33, and sampling needle 10 is moved to 33 position of the pond WBC, injects appropriate blood
Sample；
Step S6: sampling needle 10 draws suitable diluted sample in the pond WBC 33, and third syringe 43 is by WBC reagent later
It is reacted in the 21 injection ponds WBC 33；
Step S7: sampling needle 10 is moved to 34 position of the pond RBC, injects the diluted sample drawn from the pond WBC 33；
The pond step S8:CRP 35, the pond SAA 31, DIFF measuring unit, the pond WBC 33 and the pond RBC 34 respectively carry out each parameter
Parallel measurement exports the cleaning in measurement result and each channel after the completion.
Above-mentioned steps S2, step S3, step S4 sequencing with no restrictions, other steps guarantee above-mentioned steps sequence.
The above description is only a preferred embodiment of the present invention, is not intended to limit the scope of the invention, all at this
Under the design of invention, using equivalent structure transformation made by description of the invention and accompanying drawing content, or directly/it is used in it indirectly
He is included in scope of patent protection of the invention relevant technical field.
Claims (17)
1. a kind of blood test device, which is characterized in that including blood routine detection unit and SAA detection unit；The blood routine
Detection unit includes sampling needle and counting cell unit, and the SAA detection unit includes the pond SAA；The sampling needle for draw and
Blood sample is distributed to the counting cell unit and the pond SAA；The counting cell unit is used to carry out blood routine to the blood sample of distribution
The measurement of parameter, the pond SAA measure SAA parameter as dilution, the reaction vessel of SAA reagent and blood sample.
2. blood test device as described in claim 1, which is characterized in that the blood test device further includes CRP detection
Unit, the CRP detection unit include the pond CRP；The sampling needle is also used to draw and distribution blood sample is to the pond CRP, described
The pond CRP measures CRP parameter as dilution, the reaction vessel of CRP reagent and blood sample.
3. blood test device as claimed in claim 2, which is characterized in that the blood routine detection unit further includes DIFF logical
Road measuring unit, syringe unit, dilution allocation unit and negative pressure chamber；
The counting cell unit includes the pond DIFF, the pond WBC, the pond RBC, and the pond DIFF is as dilution, DIFF reagent and blood sample
Reaction vessel, the pond WBC as dilution, the reaction vessel of WBC reagent and blood sample, the pond RBC for carry out RBC and
PLT is counted；
The dilution allocation unit connects the pond SAA, the pond CRP, the pond DIFF, the pond WBC and the pond RBC；The syringe unit
For distributing dilution via the dilution allocation unit to the pond SAA, the pond CRP, the pond DIFF, the pond WBC and the pond RBC；It is described
Syringe unit is also used to for SAA reagent to be assigned to the pond SAA, CRP reagent is assigned to the pond CRP, divides WBC reagent
It is fitted on the pond WBC；DIFF reagent is assigned to the pond DIFF；
The DIFF lane testing unit is used for the classification of leucocyte；
The negative pressure chamber provides sample flow driving force for the pond WBC and the pond RBC.
4. blood test device as described in claim 1, which is characterized in that the counting cell unit includes the pond DIFF, described
The pond DIFF is provided with DIFF reagent inlet, the DIFF reagent inlet one and only one, the sampling needle be also used to draw and
Blood sample is distributed to the pond DIFF, the pond DIFF is as dilution, the reaction vessel of DIFF reagent and blood sample.
5. blood test device as claimed in claim 4, which is characterized in that the blood test device further includes CRP detection
Unit, the CRP detection unit include the pond CRP；The sampling needle is also used to draw and distribution blood sample is to the pond CRP, described
The pond CRP measures CRP parameter as dilution, the reaction vessel of CRP reagent and blood sample.
6. blood test device as claimed in claim 5, which is characterized in that the blood routine detection unit further includes DIFF logical
Road measuring unit, syringe unit, dilution allocation unit, negative pressure chamber；
The counting cell unit further includes the pond WBC, the pond RBC, and the pond WBC holds as the reaction of dilution, WBC reagent and blood sample
Device, the pond RBC are counted for carrying out RBC and PLT；
The dilution allocation unit connects the pond SAA, the pond CRP, the pond DIFF, the pond WBC and the pond RBC；The syringe unit
For distributing dilution via the dilution allocation unit to the pond SAA, the pond CRP, the pond DIFF, the pond WBC and the pond RBC；It is described
Syringe unit is also used to for SAA reagent to be assigned to the pond SAA, CRP reagent is assigned to the pond CRP, divides WBC reagent
It is fitted on the pond WBC；DIFF reagent is assigned to the pond DIFF；
The DIFF lane testing unit is used for the classification of leucocyte；
The negative pressure chamber provides sample flow driving force for the pond WBC and the pond RBC.
7. the blood test device as described in claim 3 or 6, which is characterized in that the pond SAA includes SAA pond body, second
There is SAA reagent mouth, SAA waste liquid outlet is added for laser and the second photodetector, the SAA pond body；Described second swashs
Light device and second photodetector are for SAA measurement of concetration in SAA pond body.
8. blood test device as claimed in claim 7, which is characterized in that the pond CRP includes CRP pond body, third laser
There is CRP reagent mouth, CRP waste liquid outlet is added for device and third photodetector, the CRP pond body；The third laser
With the third photodetector for CRP measurement of concetration in CRP pond body.
9. blood test device as claimed in claim 8, which is characterized in that the DIFF channel measurement unit includes first sharp
Light device, the first photodetector and flow chamber, the first laser device and first photodetector are respectively arranged on the stream
The opposite sides along sample flow direction of dynamic room；Under syringe unit effect, sample flow passes through the flow chamber, institute
It states first laser device and the classification of leucocyte is completed in first photodetector cooperation.
10. blood test device as claimed in claim 9, which is characterized in that the pond WBC and the pond RBC respectively include
There is impedance measuring unit, each impedance measuring unit includes forebay electrode, gem hole, after-bay electrode；The pond WBC and institute
The cell in the pond RBC is stated under the suction function of the negative pressure chamber one by one by the gem hole, cell passes through the gem hole
When, the forebay electrode and the after-bay electrode can generate pulse, according to number of pulses calculate WBC quantity, RBC quantity and
PLT quantity.
11. blood test device as claimed in claim 10, which is characterized in that the pond WBC further includes HGB measuring unit,
The HGB measuring unit includes light emitting diode and photelectric receiver, and the light that the light emitting diode issues passes through in the pond WBC
Reaction solution is transmitted to the photelectric receiver, calculates HGB concentration according to the transmitted intensity that the photelectric receiver receives.
12. blood test device as claimed in claim 11, which is characterized in that the blood routine detection unit further includes refrigeration
Unit, the refrigeration unit are used to control the SAA reagent and the CRP temperature of reagent at 2-8 DEG C.
13. blood test device as claimed in claim 12, which is characterized in that the blood routine detection unit further includes pre-add
Hot cell, the preheating unit are being added to each reaction tank to the SAA reagent, CRP reagent, DIFF reagent and dilution
It is preheated before.
14. blood test device as described in claim 1, which is characterized in that the blood routine detection unit further includes injection
Device unit, dilution allocation unit and negative pressure chamber；
The counting cell unit includes the pond WBC, the pond RBC, and the pond WBC holds as the reaction of dilution, WBC reagent and blood sample
Device, the pond RBC are counted for carrying out RBC and PLT；
The dilution allocation unit connects the pond SAA, the pond WBC and the pond RBC；The syringe unit is for passing through dilution
It is distributed by the dilution allocation unit to the pond SAA, the pond WBC and the pond RBC；The syringe unit is also used to SAA reagent point
It is fitted on the pond SAA, WBC reagent is assigned to the pond WBC；
The negative pressure chamber provides sample flow driving force for the pond WBC and the pond RBC.
15. blood test device as claimed in claim 14, which is characterized in that the blood routine detection unit does not include DIFF
Pond and DIFF lane testing unit.
16. blood test device as claimed in claim 14, which is characterized in that the blood routine detection unit further includes DIFF
Pond and DIFF lane testing unit, the pond DIFF is as dilution, the reaction vessel of DIFF reagent and blood sample, the dilution
Allocation unit connects the pond DIFF, the syringe unit be used for by dilution via the dilution allocation unit distribute to
The pond DIFF, the syringe unit are also used to for DIFF reagent being assigned to the pond DIFF, and the DIFF lane testing unit is used
In the classification of leucocyte.
17. blood test device as described in claim 1, which is characterized in that the pond SAA includes SAA pond body, second laser
There is SAA reagent mouth, SAA waste liquid outlet is added for device and the second photodetector, the SAA pond body；The second laser
With second photodetector for SAA measurement of concetration in SAA pond body.
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| CN201910319419.6A CN109932520A (en) | 2019-04-19 | 2019-04-19 | Blood test device |
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| CN201910319419.6A CN109932520A (en) | 2019-04-19 | 2019-04-19 | Blood test device |
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| CN112578121A (en) * | 2019-09-27 | 2021-03-30 | 深圳迈瑞生物医疗电子股份有限公司 | Sample analyzer and sample detection method |
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