CN109875931B - Cosmetic additive with anti-pollution effect and cosmetic thereof - Google Patents
Cosmetic additive with anti-pollution effect and cosmetic thereof Download PDFInfo
- Publication number
- CN109875931B CN109875931B CN201910209737.7A CN201910209737A CN109875931B CN 109875931 B CN109875931 B CN 109875931B CN 201910209737 A CN201910209737 A CN 201910209737A CN 109875931 B CN109875931 B CN 109875931B
- Authority
- CN
- China
- Prior art keywords
- parts
- extract
- skin
- cosmetic
- cosmetic additive
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Cosmetics (AREA)
Abstract
The invention discloses a cosmetic additive with an anti-pollution effect and a cosmetic thereof, aiming at providing a cosmetic additive which can effectively reduce the attachment of pollutants to skin, protect skin cells and resist the invasion of external pollutants and has the effects of anti-inflammation, repair, relief and the like, and the technical key point is that the cosmetic additive with the anti-pollution effect comprises the following components in parts by weight: 3-12 parts of water shield leaf extract, 1-10 parts of quercus robur root extract, 1-7 parts of winged seed moringa seed extract, 2-8 parts of grass green salicornia extract, 1-6 parts of aureobasidium pullulans fermentation product and 2-7 parts of ginkgo leaf extract; the cosmetic additive can be used in cosmetics, enhances the skin barrier, has excellent isolation and defense functions on the skin, and has good application prospect; belongs to the technical field of cosmetics.
Description
Technical Field
The invention discloses a cosmetic additive, in particular to a cosmetic additive with an anti-pollution effect and a cosmetic, and belongs to the technical field of cosmetics.
Background
In recent years, with the rapid development of global industrialization and urbanization, environmental pollution, particularly air pollution, is more and more serious, and skin is used as a physiological barrier of human body and is the first defense line for resisting various pollution sources. Not only can the skin be damaged by the source of respiratory inhalation, but many topically applied substances can be absorbed through the skin into cells or tissues in the body, disrupting the skin barrier function.
At present, air pollutants harmful to human health include suspended dust, particulates (PM10, PM2.5), Polycyclic Aromatic Hydrocarbons (PAHs), ozone, nitrogen oxides, sulfur oxides, carbon oxides, and the like, wherein PM2.5 is a non-negligible skin aggressor, has a large surface area, strong activity, a fine porous structure, and is more likely to be accompanied by toxic and harmful substances, such as: PAHs, heavy metals, microorganisms and the like, and PM2.5 cannot penetrate through the skin, is easy to adhere to the surface of the skin and continuously releases adsorbed toxic and harmful substances, and the harmful substances can enter the deep layer of the skin through pores to damage healthy cells of the skin, cause skin aging, and cause a series of skin problems such as allergy, dermatitis, color spots and the like. Besides air pollution, ultraviolet pollution can also cause skin damage, UVA has strong penetrating power and can directly reach the dermis layer of the skin, elastic fibers and collagen fibers are damaged, the skin is tanned, and the skin is most harmful; UVB is absorbed by ozone in the stratosphere, causing sunburn and redness, swelling, heat, pain in the skin, and in severe cases, blistering or peeling. The long-term exposure to UV radiation can cause skin aging, skin dryness, pachylosis, wrinkle formation, loss of elasticity, melanin precipitation, dermatitis, and skin cancer.
Therefore, the anti-pollution cosmetics firstly isolate the adhesion of pollutants such as PM2.5, dust, polycyclic aromatic hydrocarbon and the like to the skin, remove pollution particles on the skin, protect the skin from being damaged by the pollutants, consider skin invasion caused by light pollution, and cause the problems of skin barrier damage, skin sensitivity aggravation, skin inflammation initiation and the like when the skin is in a polluted environment for a long time. However, the current pollution-resistant cosmetics cannot effectively resist pollution sources from multiple aspects, or can not well resist the pollution, resist inflammation, relieve and repair skin barriers, and along with the gradual improvement of the awareness of people on the pollution prevention of the skin, the demand of protective cosmetics is continuously expanded, so that the development of a cosmetic additive capable of effectively preventing pollution is very important for the cosmetics.
Disclosure of Invention
The invention aims to provide a cosmetic additive with an anti-pollution effect, which can effectively reduce the attachment of pollutants to the skin, protect skin cells, resist toxic and harmful substances such as PAHs, heavy metals and dust caused by air pollution and skin aging caused by ultraviolet pollution, and has the effects of anti-inflammation, repair, relief and the like; the skin-protecting cosmetic can be applied to cosmetics, can enhance skin barrier, has excellent isolation and defense functions on skin, delays skin aging, and improves skin stain, inflammation, allergy and other problems.
The first technical scheme provided by the application is as follows:
a cosmetic additive with an anti-pollution effect comprises the following components in parts by weight: 3-12 parts of water shield leaf extract, 1-10 parts of quercus robur root extract, 1-7 parts of pterospermum indicum seed extract, 2-8 parts of carex glauca extract, 1-6 parts of aureobasidium pullulans fermentation product and 2-7 parts of ginkgo leaf extract.
Further, the cosmetic additive also comprises 2-6 parts of an alpine edelweiss extract and 1-5 parts of a mirabilis jalapa extract;
furthermore, the cosmetic additive also comprises 4-8 parts of scutellaria alpina flower/leaf/stem extract.
Preferably, the cosmetic additive comprises the following components in parts by weight: 5-9 parts of water shield leaf extract, 3-8 parts of quercus robur root extract, 3-6 parts of winged seed moringa seed extract, 4-7 parts of grass green salicornia extract, 2-5 parts of aureobasidium pullulans fermentation product and 3-6 parts of ginkgo leaf extract;
more preferably, the cosmetic additive comprises the following components in parts by weight: 6-8 parts of water shield leaf extract, 5-7 parts of quercus robur root extract, 4-5 parts of winged seed moringa seed extract, 5-6 parts of grass green salicornia extract, 3-4 parts of aureobasidium pullulans fermentation product, 4-5 parts of ginkgo leaf extract, 3-5 parts of alpine edelweiss extract and 2-4 parts of mirabilis jalapa extract;
more preferably, the cosmetic additive comprises the following components in parts by weight: 6-8 parts of water shield leaf extract, 5-7 parts of quercus robur root extract, 4-5 parts of winged seed moringa seed extract, 5-6 parts of turfgrass extract, 3-4 parts of aureobasidium pullulans fermentation product, 4-5 parts of ginkgo leaf extract, 4-5 parts of alpine edelweiss extract, 3-4 parts of mirabilis jalapa extract and 5-7 parts of alpine scutellaria flower/leaf/stem extract.
The second technical scheme provided by the invention is as follows:
the cosmetics containing the cosmetic additive with the anti-pollution effect are emulsion, essence, cream, lotion, makeup removing cream, gel, facial mask and the like. During production, the selection and preparation processes of other components in the cosmetics can be carried out according to conventional operations in the field, and the cosmetic additive with the anti-pollution effect accounts for 1-10% of the total mass of the cosmetics.
Compared with the prior art, the invention has the following beneficial effects:
(1) according to the technical scheme provided by the invention, the combination of the water shield leaf extract and the quercus robur root extract can effectively prevent benzopyrene (representative substances of PAHs) from being combined with an aromatic hydrocarbon receptor (AhR) in skin cells, so that the expression of CYP1A1 enzyme is avoided, the PAHs brought by air pollution is resisted, the activity of cells is protected, meanwhile, the active oxygen and the active nitrogen have very strong antioxidant removal activity, and a very strong affinity effect on metal is achieved, so that the skin is protected against harmful substances such as ozone, nitric oxide, sulfur oxide, heavy metal and the like, and the back of the water shield leaf can secrete agar-like mucus which is rich in saccharides and can form a layer of protective film on the surface of the skin to lock more water, so that the water shield and anti-inflammatory effects are achieved; the moringa oleifera seed extract is rich in active ingredients such as protein, is a natural cationic small molecular protein, has a lotus effect, can reduce the attachment of pollutants on the surface of skin, can resist the poison of heavy metals on skin cells, and has the effects of protecting pollution and purifying the skin in a synergistic manner.
(2) The Aureobasidium pullulans fermentation product in the technical scheme provided by the invention is rich in Aureobasidium pullulans, has excellent film forming property, and a film formed on the surface of skin has strong air resistance to oxygen and nitrogen but has strong moisture permeability; the turfgrass horn extract is rich in active ingredients such as betaine, mineral substances, amino acids and the like, can promote the synthesis of hyaluronic acid, ceramide synthetase-3 and filaggrin, prevent water loss, provide better moisturizing effect for skin, improve the synthesis of transglutaminase-1, promote the maturation of cornified envelope, repair damaged cells, form a net structure on the surface of the skin by the cooperation of the fermentation product of aureobasidium pullulans, the turfgrass horn extract and the brasenia schreberi leaf extract, serve as a water-containing protective barrier, prevent the adsorption and permeation of pollutants on the skin and effectively relieve the drying discomfort caused by the pollutants, and can effectively resist the adsorption of harmful substances such as PM2.5, dust, heavy metals and the like in the air on the skin, prevent the damage of external pollutants on the skin, achieve the aims of enhancing the skin barrier and improving the cell vitality, and the like, Effective against pollution.
(3) According to the technical scheme provided by the invention, the alpine edelweiss extract contains a large amount of edelweiss, chlorogenic acid and luteolin derivatives, can stimulate increase of glutamine transaminase-1 and involucrin levels, enhances cornified envelopes, stimulates gene expression of loricrin, proline-rich small protein, keratin 1 and keratin 10, provides strong capacity of protecting and regenerating skin barriers, and the edelweiss have excellent oxidation resistance, anti-inflammation and DNA protection characteristics and can reduce death of skin cells; the Mirabilis jalapa extract can effectively prevent skin sensitive reaction and reduce skin inflammation, redness, itching and other phenomena caused by environmental pollution, and the Mirabilis jalapa extract can help the skin to resist environmental disturbance by combining with a water shield leaf extract, a quercus robur root extract, a pterospermum pterocarpum seed extract, a carex incarnata extract and a fermentation product of aureobasidium pullulans to achieve the effects of repairing sensitive skin and resisting inflammation.
(4) According to the technical scheme provided by the invention, the scutellaria alpina flower/leaf/stem extract and the ginkgo leaf extract can absorb UAV and UVB, reduce cell membrane damage caused by ultraviolet irradiation, prevent the damage of light pollution to the skin, achieve the effects of delaying aging and removing freckles, can effectively resist the damage of various pollutants to the skin by cooperating with other components, protect skin cells, enhance the skin barrier, have excellent isolation and defense functions on the skin, and further improve the problems of skin aging, color spots, inflammation, allergy and the like.
Detailed Description
The technical solutions in the embodiments of the present invention are clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. For process parameters or conditions not specifically mentioned, it can be carried out with reference to conventional techniques.
The raw materials used in the present invention are all purchased from commercial sources. The water shield leaf extract is purchased from Guangzhou Baihabo Co., Ltd, the quercus robur root extract is purchased from Guangzhou Bochi Biotechnology Co., Ltd, the moringa oleifera seed extract is purchased from vast forest GmbH, the carex glauca extract is purchased from Yuyu Enterprise group, the Aureobasidium pullulans fermentation product is purchased from Shanghai Mega-Heng-Industrial Co., Ltd, the ginkgo leaf extract is purchased from Shanghai Gaojia leaf Enteromorpha Henry extract, the Gaoshan Leontopodium flower/leaf/stem extract is purchased from Guangzhou Runfei chemical Co., Ltd, and the mirabilis jalapa extract is purchased from Guangzhou Oyuan Biotechnology Co., Ltd.
Example 1
A cosmetic additive with an anti-pollution effect comprises the following components in parts by weight: 3 parts of water shield leaf extract, 1 part of quercus robur root extract, 1 part of moringa oleifera seed extract, 2 parts of grass green salicornia extract, 1 part of aureobasidium pullulans fermentation product and 2 parts of ginkgo leaf extract.
Example 2
A cosmetic additive with an anti-pollution effect comprises the following components in parts by weight: 5 parts of water shield leaf extract, 3 parts of quercus robur root extract, 3 parts of moringa oleifera seed extract, 4 parts of grass green salicornia extract, 2 parts of aureobasidium pullulans fermentation product and 3 parts of ginkgo leaf extract.
Example 3
A cosmetic additive with an anti-pollution effect comprises the following components in parts by weight: 9 parts of water shield leaf extract, 8 parts of quercus robur root extract, 6 parts of moringa oleifera seed extract, 7 parts of grass green salicornia extract, 5 parts of aureobasidium pullulans fermentation product and 6 parts of ginkgo leaf extract.
Example 4
A cosmetic additive with an anti-pollution effect comprises the following components in parts by weight: 12 parts of water shield leaf extract, 10 parts of quercus robur root extract, 7 parts of moringa oleifera seed extract, 8 parts of grass green salicornia extract, 6 parts of aureobasidium pullulans fermentation product and 7 parts of ginkgo leaf extract.
Example 5
A cosmetic additive with an anti-pollution effect comprises the following components in parts by weight: 3 parts of water shield leaf extract, 1 part of quercus robur root extract, 1 part of moringa oleifera seed extract, 2 parts of grass green salicornia extract, 1 part of aureobasidium pullulans fermentation product, 2 parts of ginkgo leaf extract, 2 parts of alpine edelweiss extract and 1 part of mirabilis jalapa extract.
Example 6
A cosmetic additive with an anti-pollution effect comprises the following components in parts by weight: 6 parts of water shield leaf extract, 5 parts of quercus robur root extract, 4 parts of winged seed moringa seed extract, 5 parts of grass green saline grass extract, 3 parts of aureobasidium pullulans fermentation product, 4 parts of ginkgo leaf extract, 3 parts of alpine edelweiss extract and 2 parts of mirabilis jalapa extract.
Example 7
A cosmetic additive with an anti-pollution effect comprises the following components in parts by weight: 8 parts of water shield leaf extract, 7 parts of quercus robur root extract, 5 parts of winged seed moringa seed extract, 6 parts of grass green salicornia extract, 4 parts of aureobasidium pullulans fermentation product, 5 parts of ginkgo leaf extract, 5 parts of alpine edelweiss extract and 4 parts of mirabilis jalapa extract.
Example 8
A cosmetic additive with an anti-pollution effect comprises the following components in parts by weight: 12 parts of water shield leaf extract, 10 parts of quercus robur root extract, 7 parts of pterospermum pterocarpum seed extract, 8 parts of grass green saline grass extract, 6 parts of aureobasidium pullulans fermentation product, 7 parts of ginkgo leaf extract, 6 parts of alpine edelweiss extract and 5 parts of mirabilis jalapa extract.
Example 9
A cosmetic additive with an anti-pollution effect comprises the following components in parts by weight: 3 parts of water shield leaf extract, 1 part of quercus robur root extract, 1 part of moringa oleifera seed extract, 2 parts of grass green salicornia extract, 1 part of aureobasidium pullulans fermentation product, 2 parts of ginkgo leaf extract and 4 parts of scutellaria alpina flower/leaf/stem extract.
Example 10
A cosmetic additive with an anti-pollution effect comprises the following components in parts by weight: 5 parts of water shield leaf extract, 3 parts of quercus robur root extract, 3 parts of pterocarpus pterocarpum seed extract, 4 parts of grass green saline grass extract, 2 parts of aureobasidium pullulans fermentation product, 3 parts of ginkgo leaf extract and 5 parts of scutellaria alpina flower/leaf/stem extract.
Example 11
A cosmetic additive with an anti-pollution effect comprises the following components in parts by weight: 9 parts of water shield leaf extract, 8 parts of quercus robur root extract, 6 parts of pterocarpus pterocarpum seed extract, 7 parts of grass green saline grass extract, 5 parts of aureobasidium pullulans fermentation product, 6 parts of ginkgo leaf extract and 7 parts of scutellaria alpina flower/leaf/stem extract.
Example 12
A cosmetic additive with an anti-pollution effect comprises the following components in parts by weight: 12 parts of water shield leaf extract, 10 parts of quercus robur root extract, 7 parts of pterocarpus pterocarpum seed extract, 8 parts of grass green saline grass extract, 6 parts of aureobasidium pullulans fermentation product, 7 parts of ginkgo leaf extract and 8 parts of scutellaria alpina flower/leaf/stem extract.
Example 13
A cosmetic additive with an anti-pollution effect comprises the following components in parts by weight: 3 parts of water shield leaf extract, 1 part of quercus robur root extract, 1 part of pterospermum pterocarpum seed extract, 2 parts of grass green salicornia extract, 1 part of aureobasidium pullulans fermentation product, 2 parts of ginkgo leaf extract, 2 parts of alpine edelweiss extract, 1 part of mirabilis jalapa extract and 4 parts of alpine scutellaria flower/leaf/stem extract.
Example 14
A cosmetic additive with an anti-pollution effect comprises the following components in parts by weight: 6 parts of water shield leaf extract, 5 parts of quercus robur root extract, 4 parts of pterospermum pterocarpum seed extract, 5 parts of grass green salicornia extract, 3 parts of aureobasidium pullulans fermentation product, 4 parts of ginkgo leaf extract, 4 parts of alpine edelweiss extract, 3 parts of mirabilis jalapa extract and 5 parts of alpine scutellaria flower/leaf/stem extract.
Example 15
A cosmetic additive with an anti-pollution effect comprises the following components in parts by weight: 8 parts of water shield leaf extract, 7 parts of quercus robur root extract, 5 parts of winged seed moringa seed extract, 6 parts of grass green salicornia extract, 4 parts of aureobasidium pullulans fermentation product, 5 parts of ginkgo leaf extract, 5 parts of alpine edelweiss extract, 4 parts of mirabilis jalapa extract and 7 parts of alpine scutellaria flower/leaf/stem extract.
Example 16
A cosmetic additive with an anti-pollution effect comprises the following components in parts by weight: 12 parts of water shield leaf extract, 10 parts of quercus robur root extract, 7 parts of pterospermum pterocarpum seed extract, 8 parts of grass green salicornia extract, 6 parts of aureobasidium pullulans fermentation product, 7 parts of ginkgo leaf extract, 6 parts of alpine edelweiss extract, 5 parts of mirabilis jalapa extract and 8 parts of alpine scutellaria flower/leaf/stem extract.
To demonstrate the effect of the present invention, comparative experimental examples of the present application are given below:
comparative example 1
A cosmetic additive with an anti-pollution effect comprises the following components in parts by weight: 5 parts of water shield leaf extract, 3 parts of winged seed moringa seed extract and 4 parts of grass green salicornia extract.
Comparative example 2
A cosmetic additive with an anti-pollution effect comprises the following components in parts by weight: 5 parts of water shield leaf extract, 3 parts of quercus robur root extract and 2 parts of aureobasidium pullulans fermentation product.
Comparative example 3
A cosmetic additive with an anti-pollution effect comprises the following components in parts by weight: 5 parts of quercus robur root extract, 4 parts of pterocarpus pterocarpum seed extract, 3 parts of ginkgo leaf extract, 5 parts of grass green saline grass extract and 3 parts of alpine edelweiss extract.
Comparative example 4
A cosmetic additive with an anti-pollution effect comprises the following components in parts by weight: 8 parts of water shield leaf extract, 7 parts of quercus robur root extract, 5 parts of ginkgo leaf extract, 4 parts of aureobasidium pullulans fermentation product and 4 parts of mirabilis jalapa extract.
Comparative example 5
A cosmetic additive with an anti-pollution effect comprises the following components in parts by weight: 5 parts of quercus robur root extract, 4 parts of pterocarpus pterocarpum seed extract, 3 parts of ginkgo leaf extract, 4 parts of alpine edelweiss extract and 5 parts of alpine scutellaria flower/leaf/stem extract.
Comparative example 6
A cosmetic additive with an anti-pollution effect comprises the following components in parts by weight: 6 parts of water shield leaf extract, 4 parts of winged seed moringa seed extract, 4 parts of ginkgo leaf extract, 3 parts of mirabilis jalapa extract and 5 parts of scutellaria alpina flower/leaf/stem extract.
Comparative example 7
A commercially available emulsion with anti-pollution efficacy was purchased.
Comparative example 8
Containing only the emulsion base.
The preparation method of the cosmetic additive comprises the following steps: weighing the components according to any one group of the weight in the embodiments 1-16 and the comparative examples 1-6, and stirring and mixing the components uniformly at normal temperature to obtain the nano-silver paste.
The application method of any one group of cosmetic additives in examples 1 to 16 and comparative examples 1 to 6 is to add any one group of cosmetic additives into cosmetics, wherein the cosmetic additives with the anti-pollution effect account for 1 to 10 percent of the total mass of the cosmetics.
The cosmetic additive with the anti-pollution effect is added into cosmetics, and can be prepared into skin care cosmetics such as emulsion, essence, cream, lotion, makeup removing cream, gel, facial mask and the like according to the conventional process and auxiliary materials for preparing the cosmetics. The selection of the other ingredients in the cosmetic product at the time of manufacture may be made according to conventional procedures in the art.
In order to better illustrate the advantages of the present invention, the experimental results of the technical solution provided by the present invention are given below:
1. dust adsorption test
1) Test samples: the test samples prepared by adding the cosmetic additives of examples 1 to 16 and comparative examples 1 to 6 to a common emulsion external substrate, wherein the cosmetic additive having an anti-pollution effect accounts for 5% of the total mass of the emulsion, and the emulsions of comparative examples 7 and 8.
2) The test method comprises the following steps: 115 road commuters were selected and randomly divided into 23 groups (5 per group), hands were cleaned with a hand lotion and wiped dry with paper towels. Each group applied 0.2g of the emulsion base of comparative example 8 to an area of approximately 2 square centimeters on the left forearm and 0.2g of each of the other groups of test samples to an area of approximately 2 square centimeters on the right forearm. Let them work on the road for 4 hours, then stick the dust off the forearms with 3M tape, weigh and average. The test results are shown in Table 1.
Table 1 dust adsorption test results
| Sample (I) | Dust amount/g of left forearm | Dust amount/g of right forearm | Reduction rate/%) |
| Example 1 | 0.0062 | 0.0024 | 61.22％ |
| Example 2 | 0.0048 | 0.0018 | 62.89％ |
| Example 3 | 0.0075 | 0.0027 | 63.34％ |
| Example 4 | 0.0053 | 0.0019 | 63.48％ |
| Example 5 | 0.0068 | 0.0024 | 64.05％ |
| Example 6 | 0.0084 | 0.0029 | 65.56％ |
| Example 7 | 0.0042 | 0.0014 | 65.85％ |
| Example 8 | 0.0055 | 0.0019 | 65.10％ |
| Example 9 | 0.0081 | 0.0026 | 67.77％ |
| Example 10 | 0.0090 | 0.0029 | 68.03％ |
| Example 11 | 0.0067 | 0.0021 | 68.28％ |
| Example 12 | 0.0088 | 0.0027 | 68.82％ |
| Example 13 | 0.0057 | 0.0016 | 71.95％ |
| Example 14 | 0.0064 | 0.0017 | 72.74％ |
| Example 15 | 0.0042 | 0.0011 | 73.13％ |
| Example 16 | 0.0084 | 0.0022 | 73.88％ |
| Comparative example 1 | 0.0059 | 0.0034 | 42.13％ |
| Comparative example 2 | 0.0073 | 0.0043 | 41.56％ |
| Comparative example 3 | 0.0080 | 0.0045 | 43.75％ |
| Comparative example 4 | 0.0077 | 0.0043 | 44.48％ |
| Comparative example 5 | 0.0064 | 0.0034 | 46.25％ |
| Comparative example 6 | 0.0069 | 0.0036 | 47.34％ |
| Comparative example 7 | 0.0055 | 0.0034 | 38.90％ |
From the experimental results in table 1, it can be seen that the dust amount of the right forearm is significantly reduced after the right forearm is applied with the emulsion containing the cosmetic additive of the embodiment of the present invention, wherein the dust amount is reduced by more than 70% in the embodiments 13 to 16, while the dust amount is reduced by only 38.90% after the emulsion of the comparative example 7 is applied with a certain commercially available anti-pollution emulsion, which indicates that the cosmetic additive of the present invention can significantly reduce the adsorption of pollutants such as dust on the skin. After the emulsions of comparative examples 1 to 6 were used, the amount of dust reduction was relatively lower than that of the emulsions prepared by using the cosmetic additives of the examples, which shows that the effect of adding several extracts of the cosmetic additives of the present invention to the emulsions alone was significantly inferior to the effect of adding all nine ingredients of the cosmetic additives of the present invention to the emulsions, and the effect of reducing the adhesion of dust pollutants to the skin was gradually enhanced with the increase in the types of the extracts of the present invention, and thus, it can be known that the extracts provided by the present invention have a synergistic effect and can better resist pollutant particles such as PM2.5, dust, and the like.
2. Skin barrier function test
1) The test principle is as follows: normal skin has a strong barrier function and can prevent external harmful substances from entering the skin. When barrier function is compromised, pathways are formed between keratinocytes from which water is lost. Thus, the transdermal loss of water increases when the skin barrier function is diminished and vice versa decreases. The better the skin protection layer, the higher the moisture content and the lower the value of the skin moisture loss TEWL. The test judges the strength of the skin barrier function by the percutaneous water loss (TEWL), thereby evaluating the anti-pollution efficacy of the cosmetic additive of the present invention.
2) Test samples: the cosmetic additives of examples 2, 4, 6, 8, 10, 12, 14, 16, comparative examples 1, 3, 5 were added to a common emulsion external base to prepare test samples in which the cosmetic additive having anti-contamination efficacy accounted for 5% of the total mass of the emulsion, and the emulsion of comparative example 7.
3) The test method comprises the following steps: 130 female subjects with dry and water-deficient facial skin are selected, the female subjects are 20-45 years old and randomly divided into 13 groups, 10 persons in each group are detected for three days before the detection, the face does not use any cosmetics, 0.2g of emulsion is respectively taken by each group of subjects to be coated on the facial skin, the emulsion is respectively used once every morning and evening, the samples are continuously used for 28 days, the samples are stopped at 29 days and 30 days, the TEWL values of the face are respectively measured by a Tewameter after the samples are used for 1 day and 31 days, and the TEWL values are respectively repeated for 5 times to obtain the average value. The test results are shown in Table 2.
Table 2 skin barrier function test
As can be seen from the experimental results in Table 2, the change rate of the TEWL value of the skin water loss after the emulsion added with the cosmetic additive of the embodiment of the invention is more than 60%, which is higher than that of a certain commercially available anti-pollution emulsion of the comparative example 7, and the effect of the cosmetic additive of the invention on enhancing the skin barrier function is demonstrated. The change rate of TEWL values after using the emulsions of comparative examples 1, 3 and 5 was relatively lower than that of the emulsions prepared using the cosmetic additives of the examples, indicating that the effects of enhancing the skin barrier function and reducing the loss of skin moisture are gradually enhanced as the kinds of the extracts of the present invention are increased, and thus it is understood that the extracts provided by the present invention have a synergistic effect.
3. Anti-inflammatory efficacy test
1) The test principle is as follows: the mouse auricle swelling experiment is one of non-specific inflammation models, mainly uses chemical substances as inflammatory agents to induce the mouse ear swelling, and is usually used for evaluating the anti-inflammatory activity of some synthetic compounds and plant active ingredients.
2) Test samples: the cosmetic additives of examples 1, 3, 5, 7, 9, 11, 13, 15 and comparative examples 2, 4, 6 were added to a common emulsion external base to prepare test samples in which the cosmetic additive having an anti-contamination effect was 5% by mass of the total mass of the emulsion, and the emulsion of comparative example 7.
3) The test method comprises the following steps: taking 130 male mice (female mice can generate more estrogen which has certain anti-inflammatory effect and is not suitable for anti-inflammatory experiments), randomly dividing into 13 groups, each group comprises 10 female mice, one group is blank control (applied with normal saline with equal dosage), the other groups are applied with test samples, each test sample is applied in advance for 30d, 1g is applied each time, 30 microliter of dimethylbenzene is applied to the auricle of the right ear after 30min of last administration to cause an acute inflammation model, and the left ear is not applied as a normal ear control. After 1h of xylene coating, blood was taken and sacrificed, ear pieces were punched out at the same positions of the left and right ears by a punch having a diameter of 6mm, the masses were weighed on an analytical balance, and the swelling degree and the swelling inhibition ratio were calculated by taking the average value. The results are shown in Table 3.
Wherein:
swelling degree-right ear tablet quality after inflammation-left ear tablet quality without inflammation
Swelling inhibition rate (average swelling degree of blank control group-average swelling degree of drug administration group)/average swelling degree of blank control group × 100%
Table 3 anti-inflammatory efficacy test
Note: compared to the control group,: p < 0.05, x: p is less than 0.01.
As can be seen from the experimental results of Table 3, the swelling inhibition ratio of the cosmetic additive of the present invention was higher than that of one of the commercially available anti-pollution emulsions of comparative example 7, indicating that the cosmetic additive of the present invention can significantly reduce the inflammatory swelling of mouse auricle caused by xylene. The swelling inhibition ratio using the cosmetic additives of comparative examples 2, 4, and 6 was relatively lower than that of the examples, confirming that the cosmetic additives of the present invention are reasonably compounded to have superior anti-inflammatory effects.
4. Ultraviolet resistance test
1) The test principle is as follows: the sun protection factor SPF is an important parameter for measuring the ultraviolet resistance of cosmetics, and the higher the SPF value is, the stronger the ultraviolet resistance is.
2) Test samples: samples were selected for use in the skin barrier function test.
3) The test method comprises the following steps: the SPF value of each sample is measured by a sun protection index analyzer of Labsphere company, 1g of the sample is uniformly coated on a skin-like transparent PMMA plate of 5cm multiplied by 5cm, then the plate is placed in a dark place for standing for 15 minutes, the plate is placed in a UV-2000S type ultraviolet transmittance analyzer to measure the sun protection performance, 10 different parts are taken for measurement, and the average value is taken. The test results are shown in Table 4.
TABLE 4 ultraviolet resistance test
From the experimental results of Table 4, it can be seen that the SPF value of the cosmetic additive of the present invention is higher than that of a commercially available anti-pollution emulsion of comparative example 7, indicating that the cosmetic additive of the present invention has UV resistance. The SPF value of the emulsion of the comparative example is relatively lower than that of the emulsion of the example, which shows that the compounding and the cooperation of the cosmetic additive of the invention have better ultraviolet resistance and slow down the problems of skin aging, melanin precipitation, color spots and the like caused by ultraviolet rays.
5. Benzopyrene damage test on cellular DNA
1) The test principle is as follows: the comet assay can effectively detect and quantitatively analyze the damage degree of single-strand and double-strand gaps of DNA in cells, the more the DNA is damaged, the more chain breaks and fragments are generated, the longer the length is, the more the amount of DNA is migrated under the same electrophoresis condition, the longer the migration distance is, and the damage degree of the DNA of a single cell can be determined by determining the optical density or migration length of a DNA migration part.
2) Test samples: samples were selected for use in the skin barrier function test.
3) The test method comprises the following steps: the experiment takes human keratinocytes as objects, the human keratinocytes are cultured in vitro, each component is added with 2g of test samples respectively, then cultured for 2h, then 10% benzopyrene solution is added, and a comet assay is carried out after 24h to obtain the percentage of DNA damage, so that the effect of the cosmetic additive on reducing the damage of benzopyrene to cells is evaluated. The test results are shown in Table 5.
TABLE 5 results of the benzopyrene damage test on cellular DNA
As can be seen from the experimental results of Table 5, the percentage of DNA damage of human keratinocytes to which the cosmetic additive of the present invention was added was less than that of comparative example 7, indicating that the cosmetic additive of the present invention was effective against the invasion of skin cells by benzopyrene. The DNA damage percentage of the human keratinocytes added with the cosmetic additives of comparative examples 1, 3 and 5 is higher than that of the examples, which shows that the harm of pollutants such as polycyclic aromatic hydrocarbon and the like to the skin can be better reduced by compounding the cosmetic additives of the invention, and the effect of protecting the skin cells is achieved.
In conclusion, the skin care product can effectively reduce the attachment of pollutants to the skin and resist the invasion of external pollutants through the synergistic effect of the natural active substances of the water shield leaf extract, the quercus robur root extract, the moringa oleifera seed extract, the carex glauca linn extract, the aureobasidium pullulans fermentation product, the alpine edelweiss extract, the mirabilis jalapa extract, the scutellaria alpina flower/leaf/stem extract and the ginkgo leaf extract, and has the effects of relieving, resisting inflammation, repairing and the like.
The above embodiments are preferred embodiments of the present invention, but the present invention is not limited to the above embodiments, and any other changes, modifications, substitutions, combinations, and simplifications which do not depart from the spirit and principle of the present invention should be construed as equivalents thereof, and all such changes, modifications, substitutions, combinations, and simplifications are intended to be included in the scope of the present invention.
Claims (4)
1. The cosmetic additive with the anti-pollution effect is characterized by comprising the following components in parts by weight: 3-12 parts of water shield leaf extract, 1-10 parts of quercus robur root extract, 1-7 parts of pterocarpus pterocarpum seed extract, 2-8 parts of carex glaucophyllus extract, 1-6 parts of aureobasidium pullulans fermentation product, 2-7 parts of ginkgo leaf extract, 2-6 parts of alpine edelweiss extract, 1-5 parts of mirabilis jalapa extract and 4-8 parts of scutellaria alpina flower/leaf/stem extract.
2. The cosmetic additive with anti-pollution effect as claimed in claim 1, wherein the cosmetic additive is prepared from the following components in parts by weight: 6-8 parts of water shield leaf extract, 5-7 parts of quercus robur root extract, 4-5 parts of winged seed moringa seed extract, 5-6 parts of turfgrass extract, 3-4 parts of aureobasidium pullulans fermentation product, 4-5 parts of ginkgo leaf extract, 4-5 parts of alpine edelweiss extract, 3-4 parts of mirabilis jalapa extract and 5-7 parts of alpine scutellaria flower/leaf/stem extract.
3. The cosmetic with the anti-pollution efficacy is characterized by comprising the anti-pollution efficacy cosmetic additive and a common matrix according to the mass ratio of 1-10: 99-90.
4. The cosmetic according to claim 3, wherein the cosmetic is one of lotion, essence, cream, lotion, makeup remover, gel, and mask.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910209737.7A CN109875931B (en) | 2019-03-19 | 2019-03-19 | Cosmetic additive with anti-pollution effect and cosmetic thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910209737.7A CN109875931B (en) | 2019-03-19 | 2019-03-19 | Cosmetic additive with anti-pollution effect and cosmetic thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN109875931A CN109875931A (en) | 2019-06-14 |
| CN109875931B true CN109875931B (en) | 2021-08-13 |
Family
ID=66933059
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910209737.7A Active CN109875931B (en) | 2019-03-19 | 2019-03-19 | Cosmetic additive with anti-pollution effect and cosmetic thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109875931B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111803420B (en) * | 2020-08-11 | 2023-01-31 | 现代百朗德生物科技(江苏)有限公司 | Cosmetic composite with anti-pollution heavy metal resistance |
| CN113456568A (en) * | 2021-06-30 | 2021-10-01 | 广州市科能化妆品科研有限公司 | Composition for soothing, repairing and moisturizing skin and preparation method and application thereof |
| CN113730322B (en) * | 2021-10-22 | 2023-01-03 | 广州市胜梅化妆品有限公司 | Soothing cosmetic |
| CN114146045A (en) * | 2021-11-12 | 2022-03-08 | 赣州澳丽尔化妆品有限公司 | Skin care product obtained by biological fermentation technology and preparation method thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105125449A (en) * | 2015-09-24 | 2015-12-09 | 广州市索柔生物科技有限公司 | Anti-pollution cosmetic composition |
| CN106420500A (en) * | 2016-11-30 | 2017-02-22 | 广东芭薇生物科技股份有限公司 | Composition containing inonotus obliquus extract and application of composition |
| CN107412062A (en) * | 2017-08-09 | 2017-12-01 | 广东丸美生物技术股份有限公司 | For the composition of antipollution cosmetics, liposome, cream type cosmetics, emulsion-type cosmetics and its preparation method and application |
| CN109157445A (en) * | 2018-09-07 | 2019-01-08 | 广东丸美生物技术股份有限公司 | Skin matrix and the preparation method and application thereof with antipollution and anti-inflammatory efficacy |
| CN109464339A (en) * | 2018-12-26 | 2019-03-15 | 广州蜜妆生物科技有限公司 | A kind of antipollution composition and its application |
-
2019
- 2019-03-19 CN CN201910209737.7A patent/CN109875931B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105125449A (en) * | 2015-09-24 | 2015-12-09 | 广州市索柔生物科技有限公司 | Anti-pollution cosmetic composition |
| CN106420500A (en) * | 2016-11-30 | 2017-02-22 | 广东芭薇生物科技股份有限公司 | Composition containing inonotus obliquus extract and application of composition |
| CN107412062A (en) * | 2017-08-09 | 2017-12-01 | 广东丸美生物技术股份有限公司 | For the composition of antipollution cosmetics, liposome, cream type cosmetics, emulsion-type cosmetics and its preparation method and application |
| CN109157445A (en) * | 2018-09-07 | 2019-01-08 | 广东丸美生物技术股份有限公司 | Skin matrix and the preparation method and application thereof with antipollution and anti-inflammatory efficacy |
| CN109464339A (en) * | 2018-12-26 | 2019-03-15 | 广州蜜妆生物科技有限公司 | A kind of antipollution composition and its application |
Also Published As
| Publication number | Publication date |
|---|---|
| CN109875931A (en) | 2019-06-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN109875931B (en) | Cosmetic additive with anti-pollution effect and cosmetic thereof | |
| CN107875069B (en) | Mineral mud mask and preparation method thereof | |
| CN111920728A (en) | Cosmetic relieving and repairing composition and cosmetic | |
| CN106420500B (en) | A kind of composition of the extract containing Inonotus obliquus and its application | |
| CN109549893B (en) | Composition and essence milk with blue light pollution resistance and repair effects and preparation method of essence milk | |
| KR101781556B1 (en) | Cosmetic composition for anti-aging containing red algae extracts | |
| CN113181085A (en) | Composition matrix for improving skin problems after makeup and application of composition matrix in cosmetics | |
| CN115317429B (en) | Composition containing recombinant collagen and having repairing and relieving effects, eye cream containing composition, preparation method and application | |
| CN108852869B (en) | Skin care composition for resisting blue light pollution and application thereof | |
| CN112842960A (en) | Cosmetic composition with ultraviolet resistance, whitening and aging resistance | |
| CN114404340A (en) | Plant acne-removing composition and application thereof | |
| CN114796024B (en) | Bionic sebum composition for skin barrier repair, and preparation method and application thereof | |
| KR100881143B1 (en) | Composition of skin external application containing green tea flower extract | |
| CN106420395A (en) | Anti-allergy regenerative mask fluid | |
| CN113041172B (en) | Sebum membrane bionic composition for skin barrier repair, application thereof and cosmetics | |
| CN106974854B (en) | Skin-activating and repairing essence | |
| CN112263493A (en) | Sunscreen composition, sunscreen gel containing sunscreen composition and preparation method of sunscreen gel | |
| KR20150106244A (en) | UV protection and moisturizing cosmetic composition | |
| CN115177570A (en) | Composition with soothing and repairing effects and preparation method and application thereof | |
| CN110664671A (en) | Plant extract composition and application thereof in sunscreen, after-sun repair, photoaging prevention and whitening cosmetics | |
| KR102337308B1 (en) | Composition for preventing or improving skin aging containing (-)-eudesmin | |
| CN114533618A (en) | Whitening and repairing composition and preparation method and application thereof | |
| CN111419732A (en) | Protective composition and application thereof in indoor protective cosmetics | |
| CN112915060A (en) | Emulsion containing anti-aging composition and preparation method thereof | |
| CN113384510A (en) | Fermented composition with anti-photoaging, relieving and cooling effects and preparation method and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |