CN114146045A - Skin care product obtained by biological fermentation technology and preparation method thereof - Google Patents
Skin care product obtained by biological fermentation technology and preparation method thereof Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
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- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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Abstract
The invention belongs to the technical field of skin care products, and discloses a skin care product obtained by using a biotechnology and a preparation method thereof, wherein the skin care product obtained by using the biotechnology comprises the following raw materials in parts by weight: 2-10 parts of vegetable oil, 2-5 parts of propylene glycol dicaprate, 1-2 parts of 1, 2-pentanediol and 1-3 parts of octyl dodecanol xyloside; 1-2 parts of octyl dodecanol and 1-3 parts of an emulsifier; 1-3 parts of acryloyl dimethyl ammonium taurate/VP copolymer, 1-5 parts of isostearyl alcohol and 1-3 parts of cetearyl alcohol; 1-5 parts of aureobasidium pullulans/barley seed fermentation product filtrate, 0.3-1.0 part of p-hydroxyacetophenone, 1-5 parts of 1, 3-propylene glycol, 0.01-0.3 part of sodium hyaluronate and the balance of water phase components. The technical scheme of the invention aims to improve the moisturizing effect and the absorption effect of the skin care product by adding the aureobasidium pullulans into the skin care product.
Description
Technical Field
The invention relates to the technical field of skin care products, in particular to a skin care product obtained by utilizing a biological fermentation technology and a preparation method thereof.
Background
Water is indispensable for human metabolism, the water taken by human bodies every day reaches the surface of the skin of people very rarely and rarely, the skin is lack of water, a plurality of skin problems such as dead skin, wrinkling, greasy skin, blackhead and the like are caused, and the skin is dried and damaged from inside to outside due to the influence of dry environment, sun, environmental pollution, air conditioning, insufficient sleep and various pressures, so that the skin is dry and damaged, and is dry and loses elasticity, thereby causing the aging problem. If the skin of a human body is lack of moistening of sebum and moisture, the outermost epidermal cuticle layer is dried up, aging is accelerated, desquamation occurs, and the air conditioner can also pump away the moisture, so that people can feel dry and astringent, desquamation is increased, symptoms such as dry seborrheic dermatitis, white pityriasis and the like easily occur, and therefore, the moisture retention is not slow. Most skin care products have the moisturizing function, and the film forming agent is added into the skin care products to maintain or increase the moisture content of the skin and improve the absorption and moisturizing effects.
The skin care products commonly used in the market at present mainly have three troubles: 1. the moisturizing effect cannot be lasting; 2. the absorption performance is poor, and the water only floats on the surface of the skin; 3. after the use, the feeling is sticky and greasy, and the uncomfortable feeling is obvious. Therefore, a skin care product with lasting moisturizing effect, fresh and smooth skin feel, no stickiness, good absorption and good safety is urgently needed.
Disclosure of Invention
In order to solve the problems in the prior art, the invention aims to provide a skin care product obtained by utilizing a biological fermentation technology and a preparation method thereof, and aims to improve the moisturizing effect and the absorption effect of the skin care product by adding aureobasidium pullulans into the skin care product.
In order to realize the purpose, the invention provides a preparation method of a skin care product obtained by utilizing biotechnology, which comprises the following steps:
a. adding vegetable oil, propylene glycol dicaprate, emulsifier, isostearyl alcohol and cetostearyl alcohol into an oil phase pot, stirring and mixing, heating to 75-80 ℃, and stirring and mixing until the mixture is completely dissolved to serve as an oil phase;
b. adding propylene glycol and sodium hyaluronate into a beaker, and stirring and mixing uniformly for later use;
c. adding the water phase component, the propylene glycol and sodium hyaluronate mixed solution into a water phase pot, stirring at normal temperature until the water phase component, the propylene glycol and the sodium hyaluronate mixed solution are completely dissolved, adding the acryloyl dimethyl ammonium taurate/VP copolymer after the water phase component, uniformly stirring, injecting steam, heating to 80-85 ℃, and keeping the temperature for 5-10 minutes;
d. adding propylene glycol dicaprate, octyl dodecanol xyloside and octyl dodecanol into the oil phase in the step a, and uniformly stirring for later use;
e. adding hydroxyacetophenone into the water phase pot in the step c, and stirring uniformly for later use;
f. respectively adding 85-90% of the water phase obtained in the step e and all the oil phase obtained in the step d into an emulsifying and stirring pot for emulsification, and controlling the temperature to be 80-85 ℃;
g. after the reaction in the step f is carried out for 8-10 minutes, adding the residual 10-15% of water phase, and starting to shear the solution in the emulsifying pot, wherein the shearing speed is 2800r/min-3880r/min, and the shearing time is 5-6 minutes;
h. and g, after the shearing in the step g is finished, injecting cooling water to cool the solution, after cooling to below 38 ℃, adding the aureobasidium pullulans/barley seed fermentation product filtrate, uniformly stirring, discharging, and sealing and storing.
Optionally, the emulsifying pot is preheated by injecting steam into the emulsifying pot before step f.
Optionally, the stirring time for the dissolution of the aqueous phase in step c is between 10 minutes and 15 minutes.
Optionally, in step f, the rotation speed of the emulsifying pot is 20r/min-40r/min, and the vacuum pressure is 0.25 mpa-0.35 mpa.
Optionally, the skin care product has a pH of 5.5-7.4.
Optionally, the vegetable oil is 2-10 parts by weight, the propylene glycol dicaprate is 2-5 parts by weight, 1-3 parts of emulsifier, 1-5 parts of isostearyl alcohol, 1-3 parts of cetearyl alcohol, 1-3 parts of acryloyl dimethyl ammonium taurate/VP copolymer, 1-3 parts of octyl dodecanol xyloside, 1-2 parts of octyl dodecanol, 0.3 to 1.0 weight part of p-hydroxyacetophenone, 1 to 5 weight parts of aureobasidium pullulans/barley seed fermentation product filtrate, 1-5 parts of propylene glycol, 0.01-0.3 part of sodium hyaluronate, and the aqueous phase component comprises glycerol, butanediol and deionized water.
Optionally, the aureobasidium pullulans comprises by mass percent: 35 to 45 percent of potato and 55 to 65 percent of barley seed.
Optionally, the potato and the barley seeds need to be inoculated with yeast enzyme for fermentation treatment.
Alternatively, the sodium hyaluronate has a molecular weight of 130 ten thousand.
Optionally, the emulsifier is a polycrystalline structure.
Specifically, because the high temperature resistant time of the propylene glycol dicaprate, the octyl dodecanol xyloside and the octyl dodecanol is shorter, the oil phase is added before the oil phase is prepared to be added into the emulsifying pot after the temperature of the oil phase is raised; similarly, because the high temperature resistance time of the hydroxyacetophenone is short, the hydroxyacetophenone is added into the water phase after the water phase is heated and before the water phase is prepared to be added into the emulsifying pot, so as to shorten the time of the hydroxyacetophenone at high temperature. And the purpose that the water phase is added into the emulsifying pot twice is that 10% -15% of the water phase reserved later is the residual water phase pumped in after the oil phase is completely pumped out, and the effect of flushing a pipeline can be achieved.
It is to be noted that when the oil phase and the water phase are added into the emulsifying pot, steam is injected into the emulsifying pot in advance, the emulsifying pot is preheated to ensure that the cooling water in the jacket of the emulsifying pot is completely discharged, the emulsifying pot is vacuumized, the pressure in the pot is between-0.25 and 0.35mpa after vacuumization, meanwhile, the sealing degree of the emulsifying pot needs to be checked in time, the temperature change condition in the emulsifying pot needs to be observed in the emulsifying process of the water phase and the oil phase, the temperature is supplemented in time, and the temperature is controlled to be between 80 and 85 ℃.
After the oil phase and the water phase are emulsified, the solution is cooled to a temperature lower than 38 ℃, then the aureobasidium pullulans/barley seed fermentation product filtrate is added and uniformly stirred, and finally the aureobasidium pullulans is added, so that a layer of protective film is integrally formed in the solution, and the effects of improving the moisture retention effect and the absorption effect and reducing wrinkles are achieved.
According to the technical scheme, the aureobasidium pullulans is added into the components of the skin care product to improve the absorption effect and the moisturizing effect of the skin care product, and the novel biotechnology (aureobasidium pullulans/barley seed fermentation product filtrate) is applied and used as the core technology of the product; extracting biological fermentation essence from the fermentation product filtrate of the aureobasidium pullulans/barley seeds by adopting unique microbial fermentation and separation technology; the product is applied to a product formula, and the moisturizing conditioning components in the formula are combined, so that the vitality and elasticity of the product are enhanced, the ecological balance of skin probiotics is adjusted, and a protective film is formed, thereby realizing the improvement of the resistance of the external environment and achieving the purposes of improving the absorption effect and the moisturizing effect.
The skin care product obtained by the invention contains aureobasidium pullulans which can help the synthesis of collagen and glycosaminoglycan, reduce fine lines, improve and condition skin, effectively improve wrinkles, enhance the firmness and luster of the skin and improve skin color; the face mask can greatly promote the production of collagen, enables the face to be full and elastic, improves the water content and moisture retention of the skin, enables the skin to feel soft and smooth, and enables the skin to be glowing from inside to outside. The moisturizing conditioning components in the formula are combined, so that the product has the effects of enhancing vitality and elasticity, regulating ecological balance of skin probiotics, forming a protective film, improving the resistance of external conditions, and reducing skin injury caused by climate change, environmental factors and the like. The aureobasidium pullulans is applied to the skin, so that the moisturizing effect and the absorption effect can be improved, and the wrinkle reducing effect can be realized.
Detailed Description
The present invention is further illustrated below with reference to specific examples.
Example 1
The embodiment provides a preparation method of a skin care product obtained by using a biotechnology, and the preparation method of the skin care product comprises the following steps: adding vegetable oil, propylene glycol dicaprate, emulsifier, isostearyl alcohol and cetostearyl alcohol into an oil phase pot, stirring and mixing, heating to 75-80 ℃, and stirring and mixing until the mixture is completely dissolved to serve as an oil phase; adding the propylene glycol and the sodium hyaluronate into a beaker, and stirring and mixing uniformly for later use; adding the water phase component, the propylene glycol and the sodium hyaluronate mixed solution into a water phase pot, and stirring at normal temperature until the water phase component, the propylene glycol and the sodium hyaluronate mixed solution are completely dissolved, wherein the stirring time is 10-15 minutes; after complete dissolution is ensured, adding the acryloyl dimethyl ammonium taurate/VP copolymer, stirring uniformly, injecting steam, heating to 80-85 ℃, and keeping the temperature for 5-10 minutes; adding propylene glycol dicaprate, octyl dodecanol xyloside and octyl dodecanol into the oil phase, and stirring uniformly for later use; adding hydroxyacetophenone with the formula amount into the water phase pot, and stirring uniformly for later use; injecting steam into the emulsifying pot, and preheating; respectively adding the prepared 85-90% of water phase and all the prepared oil phase into an emulsifying and stirring pot for emulsification, controlling the temperature to be 80-85 ℃, the rotating speed of the emulsifying pot to be 20-40 r/min, and the vacuum pressure to be 0.25-0.35 mpa; after the emulsification pot reacts for 8-10 minutes, adding the residual 10-15% of water phase, and starting to shear the solution in the emulsification pot at a high speed to emulsify and fuse the solution in the emulsification pot as soon as possible, wherein the shearing speed is 2800r/min-3880r/min, and the shearing time is 5-6 minutes; after the shearing is finished, cooling water is injected into the emulsifying pot to cool the solution in the emulsifying pot, after the solution is cooled to below 38 ℃, the aureobasidium pullulans/barley seed fermentation product filtrate and the solution are added, mixed, stirred uniformly and discharged, and sealed and stored.
In this embodiment, the vegetable oil is 2 parts by weight, the propylene glycol dicaprate is 2 parts by weight, the emulsifier is 1 part by weight, the isostearyl alcohol is 1 part by weight, the cetearyl alcohol is 1 part by weight, the ammonium acryloyldimethyl taurate/VP copolymer is 1 part by weight, the octyldodecanol xyloside is 1 part by weight, the octyldodecanol is 1 part by weight, the p-hydroxyacetophenone is 0.3 part by weight, the fermentation product filtrate of aureobasidium pullulanase/barley seeds is 1 part by weight, the propylene glycol is 1 part by weight, the sodium hyaluronate is 0.01 part by weight, and the aqueous phase component includes glycerin, butylene glycol and deionized water.
In this example, the skin care product has a PH of 5.5 to 7.4.
In this embodiment, the aureobasidium pullulans comprises, by mass: 35 to 45 percent of potato and 55 to 65 percent of barley seed.
In this embodiment, the potato and barley seeds need to be inoculated with yeast enzyme for fermentation treatment.
In this example, the molecular weight of the sodium hyaluronate was 130 ten thousand.
In this embodiment, the emulsifier has a polycrystalline structure.
The aureobasidium pullulans is added into a formula of the skin care product, so that the moisturizing effect and the absorption effect of the skin care product can be improved, and understandably, when the skin well absorbs moisture and nutrient substances of the skin care product, the skin vitality can be improved and the generation of wrinkles can be reduced. The aureobasidium pullulans comprises 35-45% of potato and 55-65% of barley seeds, wherein the potato and the barley seeds need to be ground and then inoculated with yeast enzyme for fermentation treatment.
After the oil phase and the water phase are emulsified, the solution is cooled to a temperature lower than 38 ℃, then the aureobasidium pullulans/barley seed fermentation product filtrate is added and uniformly stirred, and finally the aureobasidium pullulans is added, so that a layer of protective film is integrally formed in the solution, and the effects of improving the moisture retention effect and the absorption effect and reducing wrinkles are achieved.
Example 2
The embodiment provides a preparation method of a skin care product obtained by using a biotechnology, and the preparation method of the skin care product comprises the following steps: adding vegetable oil, propylene glycol dicaprate, emulsifier, isostearyl alcohol and cetostearyl alcohol into an oil phase pot, stirring and mixing, heating to 75-80 ℃, and stirring and mixing until the mixture is completely dissolved to serve as an oil phase; adding the propylene glycol and the sodium hyaluronate into a beaker, and stirring and mixing uniformly for later use; adding the water phase component, the propylene glycol and the sodium hyaluronate mixed solution into a water phase pot, and stirring at normal temperature until the water phase component, the propylene glycol and the sodium hyaluronate mixed solution are completely dissolved, wherein the stirring time is 10-15 minutes; after complete dissolution is ensured, adding the acryloyl dimethyl ammonium taurate/VP copolymer, stirring uniformly, injecting steam, heating to 80-85 ℃, and keeping the temperature for 5-10 minutes; adding propylene glycol dicaprate, octyl dodecanol xyloside and octyl dodecanol into the oil phase, and stirring uniformly for later use; adding hydroxyacetophenone with the formula amount into the water phase pot, and stirring uniformly for later use; injecting steam into the emulsifying pot, and preheating; respectively adding the prepared 85-90% of water phase and all the prepared oil phase into an emulsifying and stirring pot for emulsification, controlling the temperature to be 80-85 ℃, the rotating speed of the emulsifying pot to be 20-40 r/min, and the vacuum pressure to be 0.25-0.35 mpa; after the emulsification pot reacts for 8-10 minutes, adding the residual 10-15% of water phase, and starting to shear the solution in the emulsification pot at a high speed to emulsify and fuse the solution in the emulsification pot as soon as possible, wherein the shearing speed is 2800r/min-3880r/min, and the shearing time is 5-6 minutes; after the shearing is finished, cooling water is injected into the emulsifying pot to cool the solution in the emulsifying pot, after the solution is cooled to below 38 ℃, the aureobasidium pullulans/barley seed fermentation product filtrate and the solution are added, mixed, stirred uniformly and discharged, and sealed and stored.
In this embodiment, the vegetable oil is 3.5 parts by weight, the propylene glycol dicaprate is 3 parts by weight, the emulsifier is 1.5 parts by weight, the isostearyl alcohol is 2 parts by weight, the cetearyl alcohol is 1.3 parts by weight, the ammonium acryloyldimethyl taurate/VP copolymer is 1.4 parts by weight, the octyldodecanol xyloside is 1.5 parts by weight, the octyldodecanol is 1.3 parts by weight, the p-hydroxyacetophenone is 0.4 parts by weight, the fermentation product filtrate of the brevibacterium pullulanase/barley seeds is 2.5 parts by weight, the propylene glycol is 3 parts by weight, the sodium hyaluronate is 0.05 parts by weight, and the aqueous phase component includes glycerin, butylene glycol and deionized water.
In this example, the skin care product has a PH of 5.5 to 7.4.
In this embodiment, the aureobasidium pullulans comprises, by mass: 35 to 45 percent of potato and 55 to 65 percent of barley seed.
In this embodiment, the potato and barley seeds need to be inoculated with yeast enzyme for fermentation treatment.
In this example, the molecular weight of the sodium hyaluronate was 130 ten thousand.
In this embodiment, the emulsifier has a polycrystalline structure.
The aureobasidium pullulans is added into a formula of the skin care product, so that the moisturizing effect and the absorption effect of the skin care product can be improved, and understandably, when the skin well absorbs moisture and nutrient substances of the skin care product, the skin vitality can be improved and the generation of wrinkles can be reduced. The aureobasidium pullulans comprises 35-45% of potato and 55-65% of barley seeds, wherein the potato and the barley seeds need to be ground and then inoculated with yeast enzyme for fermentation treatment.
After the oil phase and the water phase are emulsified, the solution is cooled to a temperature lower than 38 ℃, then the aureobasidium pullulans/barley seed fermentation product filtrate is added and uniformly stirred, and finally the aureobasidium pullulans is added, so that a layer of protective film is integrally formed in the solution, and the effects of improving the moisture retention effect and the absorption effect and reducing wrinkles are achieved.
Example 3
The embodiment provides a preparation method of a skin care product obtained by using a biotechnology, and the preparation method of the skin care product comprises the following steps: adding vegetable oil, propylene glycol dicaprate, emulsifier, isostearyl alcohol and cetostearyl alcohol into an oil phase pot, stirring and mixing, heating to 75-80 ℃, and stirring and mixing until the mixture is completely dissolved to serve as an oil phase; adding the propylene glycol and the sodium hyaluronate into a beaker, and stirring and mixing uniformly for later use; adding the water phase component, the propylene glycol and the sodium hyaluronate mixed solution into a water phase pot, and stirring at normal temperature until the water phase component, the propylene glycol and the sodium hyaluronate mixed solution are completely dissolved, wherein the stirring time is 10-15 minutes; after complete dissolution is ensured, adding the acryloyl dimethyl ammonium taurate/VP copolymer, stirring uniformly, injecting steam, heating to 80-85 ℃, and keeping the temperature for 5-10 minutes; adding propylene glycol dicaprate, octyl dodecanol xyloside and octyl dodecanol into the oil phase, and stirring uniformly for later use; adding hydroxyacetophenone with the formula amount into the water phase pot, and stirring uniformly for later use; injecting steam into the emulsifying pot, and preheating; respectively adding the prepared 85-90% of water phase and all the prepared oil phase into an emulsifying and stirring pot for emulsification, controlling the temperature to be 80-85 ℃, the rotating speed of the emulsifying pot to be 20-40 r/min, and the vacuum pressure to be 0.25-0.35 mpa; after the emulsification pot reacts for 8-10 minutes, adding the residual 10-15% of water phase, and starting to shear the solution in the emulsification pot at a high speed to emulsify and fuse the solution in the emulsification pot as soon as possible, wherein the shearing speed is 2800r/min-3880r/min, and the shearing time is 5-6 minutes; after the shearing is finished, cooling water is injected into the emulsifying pot to cool the solution in the emulsifying pot, after the solution is cooled to below 38 ℃, the aureobasidium pullulans/barley seed fermentation product filtrate and the solution are added, mixed, stirred uniformly and discharged, and sealed and stored.
In this embodiment, the vegetable oil is 10 parts by weight, the propylene glycol dicaprate is 4 parts by weight, the emulsifier is 2 parts by weight, the isostearyl alcohol is 3 parts by weight, the cetearyl alcohol is 2 parts by weight, the ammonium acryloyldimethyl taurate/VP copolymer is 1.5 parts by weight, the octyldodecanol xyloside is 2 parts by weight, the octyldodecanol is 1 part by weight, the p-hydroxyacetophenone is 1 part by weight, the fermentation product filtrate of aureobasidium pullulanase/barley seeds is 3 parts by weight, the propylene glycol is 4 parts by weight, the sodium hyaluronate is 0.3 part by weight, and the aqueous phase component includes glycerin, butylene glycol and deionized water.
In this example, the skin care product has a PH of 5.5 to 7.4.
In this embodiment, the aureobasidium pullulans comprises, by mass: 35 to 45 percent of potato and 55 to 65 percent of barley seed.
In this embodiment, the potato and barley seeds need to be inoculated with yeast enzyme for fermentation treatment.
In this example, the molecular weight of the sodium hyaluronate was 130 ten thousand.
In this embodiment, the emulsifier has a polycrystalline structure.
The aureobasidium pullulans is added into a formula of the skin care product, so that the moisturizing effect and the absorption effect of the skin care product can be improved, and understandably, when the skin well absorbs moisture and nutrient substances of the skin care product, the skin vitality can be improved and the generation of wrinkles can be reduced. The aureobasidium pullulans comprises 35-45% of potato and 55-65% of barley seeds, wherein the potato and the barley seeds need to be ground and then inoculated with yeast enzyme for fermentation treatment.
After the oil phase and the water phase are emulsified, the solution is cooled to a temperature lower than 38 ℃, then the aureobasidium pullulans/barley seed fermentation product filtrate is added and uniformly stirred, and finally the aureobasidium pullulans is added, so that a layer of protective film is integrally formed in the solution, and the effects of improving the moisture retention effect and the absorption effect and reducing wrinkles are achieved.
Comparative example 1
The comparative example provides a method for preparing a skin care product from a fermentation product filtrate of aureobasidium pullulans-free/barley seeds, which comprises the following steps: adding vegetable oil, propylene glycol dicaprate, emulsifier, isostearyl alcohol and cetostearyl alcohol into an oil phase pot, stirring and mixing, heating to 75-80 ℃, and stirring and mixing until the mixture is completely dissolved to serve as an oil phase; adding the propylene glycol and the sodium hyaluronate into a beaker, and stirring and mixing uniformly for later use; adding the water phase component, the propylene glycol and the sodium hyaluronate mixed solution into a water phase pot, and stirring at normal temperature until the water phase component, the propylene glycol and the sodium hyaluronate mixed solution are completely dissolved, wherein the stirring time is 10-15 minutes; after complete dissolution is ensured, adding the acryloyl dimethyl ammonium taurate/VP copolymer, stirring uniformly, injecting steam, heating to 80-85 ℃, and keeping the temperature for 5-10 minutes; adding propylene glycol dicaprate, octyl dodecanol xyloside and octyl dodecanol into the oil phase, and stirring uniformly for later use; adding hydroxyacetophenone with the formula amount into the water phase pot, and stirring uniformly for later use; injecting steam into the emulsifying pot, and preheating; respectively adding the prepared 85-90% of water phase and all the prepared oil phase into an emulsifying and stirring pot for emulsification, controlling the temperature to be 80-85 ℃, the rotating speed of the emulsifying pot to be 20-40 r/min, and the vacuum pressure to be 0.25-0.35 mpa; after the emulsification pot reacts for 8-10 minutes, adding the residual 10-15% of water phase, and starting to shear the solution in the emulsification pot at a high speed to emulsify and fuse the solution in the emulsification pot as soon as possible, wherein the shearing speed is 2800r/min-3880r/min, and the shearing time is 5-6 minutes; after the shearing is finished, cooling water is injected into the emulsifying pot to cool the solution in the emulsifying pot, and the solution is cooled, sealed and stored.
In this comparative example, the vegetable oil was 2 parts by weight, the propylene glycol dicaprate was 2 parts by weight, the emulsifier was 1 part by weight, the isostearyl alcohol was 1 part by weight, the cetearyl alcohol was 1 part by weight, the ammonium acryloyldimethyl taurate/VP copolymer was 1 part by weight, the octyldodecanol xyloside was 1 part by weight, the octyldodecanol was 1 part by weight, the p-hydroxyacetophenone was 0.3 part by weight, the propylene glycol was 1 part by weight, the sodium hyaluronate was 0.01 part by weight, and the aqueous phase component included glycerin, butylene glycol, and deionized water; the molecular weight of the sodium hyaluronate is 130 ten thousand; the emulsifier is of a polycrystalline structure.
In this comparative example, the skin care product had a pH of 5.5 to 7.4.
Comparative example 2
The comparative example provides a method for preparing a skin care product from a fermentation product filtrate of aureobasidium pullulans-free/barley seeds, which comprises the following steps: adding vegetable oil, propylene glycol dicaprate, emulsifier, isostearyl alcohol and cetostearyl alcohol into an oil phase pot, stirring and mixing, heating to 75-80 ℃, and stirring and mixing until the mixture is completely dissolved to serve as an oil phase; adding the propylene glycol and the sodium hyaluronate into a beaker, and stirring and mixing uniformly for later use; adding the water phase component, the propylene glycol and the sodium hyaluronate mixed solution into a water phase pot, and stirring at normal temperature until the water phase component, the propylene glycol and the sodium hyaluronate mixed solution are completely dissolved, wherein the stirring time is 10-15 minutes; after complete dissolution is ensured, adding the acryloyl dimethyl ammonium taurate/VP copolymer, stirring uniformly, injecting steam, heating to 80-85 ℃, and keeping the temperature for 5-10 minutes; adding propylene glycol dicaprate, octyl dodecanol xyloside and octyl dodecanol into the oil phase, and stirring uniformly for later use; adding hydroxyacetophenone with the formula amount into the water phase pot, and stirring uniformly for later use; injecting steam into the emulsifying pot, and preheating; respectively adding the prepared 85-90% of water phase and all the prepared oil phase into an emulsifying and stirring pot for emulsification, controlling the temperature to be 80-85 ℃, the rotating speed of the emulsifying pot to be 20-40 r/min, and the vacuum pressure to be 0.25-0.35 mpa; after the emulsification pot reacts for 8-10 minutes, adding the residual 10-15% of water phase, and starting to shear the solution in the emulsification pot at a high speed to emulsify and fuse the solution in the emulsification pot as soon as possible, wherein the shearing speed is 2800r/min-3880r/min, and the shearing time is 5-6 minutes; after the shearing is finished, cooling water is injected into the emulsifying pot to cool the solution in the emulsifying pot, and the solution is cooled, sealed and stored.
In this comparative example, the vegetable oil was 3.5 parts by weight, the propylene glycol dicaprate was 3 parts by weight, the emulsifier was 1.5 parts by weight, the isostearyl alcohol was 2 parts by weight, the cetearyl alcohol was 1.3 parts by weight, the ammonium acryloyldimethyl taurate/VP copolymer was 1.4 parts by weight, the octyldodecanol xyloside was 1.5 parts by weight, the octyldodecanol was 1.3 parts by weight, the p-hydroxyacetophenone was 0.4 parts by weight, the sodium hyaluronate was 0.05 parts by weight, and the aqueous phase component included glycerin, butylene glycol, and deionized water; the molecular weight of the sodium hyaluronate is 130 ten thousand; the emulsifier is of a polycrystalline structure.
In this comparative example, the skin care product had a pH of 5.5 to 7.4.
Comparative example 3
The comparative example provides a method for preparing a skin care product from a fermentation product filtrate of aureobasidium pullulans-free/barley seeds, which comprises the following steps: adding vegetable oil, propylene glycol dicaprate, emulsifier, isostearyl alcohol and cetostearyl alcohol into an oil phase pot, stirring and mixing, heating to 75-80 ℃, and stirring and mixing until the mixture is completely dissolved to serve as an oil phase; adding the propylene glycol and the sodium hyaluronate into a beaker, and stirring and mixing uniformly for later use; adding the water phase component, the propylene glycol and the sodium hyaluronate mixed solution into a water phase pot, and stirring at normal temperature until the water phase component, the propylene glycol and the sodium hyaluronate mixed solution are completely dissolved, wherein the stirring time is 10-15 minutes; after complete dissolution is ensured, adding the acryloyl dimethyl ammonium taurate/VP copolymer, stirring uniformly, injecting steam, heating to 80-85 ℃, and keeping the temperature for 5-10 minutes; adding propylene glycol dicaprate, octyl dodecanol xyloside and octyl dodecanol into the oil phase, and stirring uniformly for later use; adding hydroxyacetophenone with the formula amount into the water phase pot, and stirring uniformly for later use; injecting steam into the emulsifying pot, and preheating; respectively adding the prepared 85-90% of water phase and all the prepared oil phase into an emulsifying and stirring pot for emulsification, controlling the temperature to be 80-85 ℃, the rotating speed of the emulsifying pot to be 20-40 r/min, and the vacuum pressure to be 0.25-0.35 mpa; after the emulsification pot reacts for 8-10 minutes, adding the residual 10-15% of water phase, and starting to shear the solution in the emulsification pot at a high speed to emulsify and fuse the solution in the emulsification pot as soon as possible, wherein the shearing speed is 2800r/min-3880r/min, and the shearing time is 5-6 minutes; after the shearing is finished, cooling water is injected into the emulsifying pot to cool the solution in the emulsifying pot, and the solution is cooled, sealed and stored.
In this comparative example, the vegetable oil was 10 parts by weight, the propylene glycol didecanoate was 4 parts by weight, the emulsifier was 2 parts by weight, the isostearyl alcohol was 3 parts by weight, the cetearyl alcohol was 2 parts by weight, the ammonium acryloyldimethyl taurate/VP copolymer was 1.5 parts by weight, the octyldodecanol xyloside was 2 parts by weight, the octyldodecanol was 1 part by weight, the p-hydroxyacetophenone was 1 part by weight, the propylene glycol was 4 parts by weight, the sodium hyaluronate was 0.3 part by weight, and the aqueous phase component included glycerin, butylene glycol, and deionized water; the molecular weight of the sodium hyaluronate is 130 ten thousand; the emulsifier is of a polycrystalline structure.
In this comparative example, the skin care product had a pH of 5.5 to 7.4.
The experimental effects can be seen in the following tables 1,2 and 3, wherein table 1 is an analysis table of the skin moisturizing and conditioning collagen lifting value percentage data of the skin care products of the examples and the comparative examples, and the details are shown in the following table:
table 1 table of percentage data analysis of skin moisturizing and conditioning collagen lifting values of skin care products of examples and comparative examples at different time periods
Examples 1 to 3 are skin care products prepared from raw materials containing 1 part, 2 parts and 3 parts of the filtrate of fermentation products of Brevibacterium pullulans/barley seeds, respectively; comparative examples 1 to 3 are skin care products prepared in examples 1 to 3, respectively, which did not contain the fermentation product filtrate of aureobasidium pullulans/barley seeds, and the skin moisturizing conditioning collagen increase value increased with time to a peak value and gradually decreased, the skin moisturizing conditioning collagen increase values of examples 1 to 3 were significantly higher than those of comparative examples 1 to 3, and the skin moisturizing conditioning collagen increase values were better as the amount of the fermentation product filtrate of aureobasidium pullulans/barley seeds in the raw material was larger than those of comparative examples 1 to 3, and the comparative examples 1 to 3 were more effective as the amount of the fermentation product filtrate of aureobasidium pullulans/barley seeds in the raw material was larger.
Table 2 is an analysis of the moisture content of the stratum corneum of the skin care product of example 1 applied and no product applied, as detailed in the table below:
TABLE 2 comparison of moisture content of stratum corneum with and without the skin care product applied at different time periods
As can be seen from table 2, after the skin care product is applied, the moisture content of the stratum corneum is significantly higher than that of the skin care product which is not applied, and the moisture content is increased along with the increase of the time, and after the skin care product is applied for a certain time, the moisture is kept at a certain value which is higher than that of the skin care product which is not applied, so that the skin care product has the effects of moisturizing and promoting moisture absorption.
Table 3 shows comparative analysis of wrinkle reduction degree after observing the skin with 5% of fermentation product filtrate of Brevibacterium pullulanase/barley seed, Hamamelis virginiana extract, collagen, etc. applied on the skin for 2 weeks:
TABLE 3 analysis of wrinkle reduction
As is apparent from Table 3, the addition of Brevibacterium pullulanase was effective in removing wrinkles, and the longer the use time was, the better the wrinkle removal effect was.
The present invention is not limited to the above-described alternative embodiments, and various other forms of products can be obtained by anyone in light of the present invention. The above detailed description should not be taken as limiting the scope of the invention, which is defined in the claims, and which the description is intended to be interpreted accordingly.
Claims (10)
1. A preparation method of a skin care product obtained by utilizing biotechnology is characterized by comprising the following steps:
a. adding vegetable oil, propylene glycol dicaprate, emulsifier, isostearyl alcohol and cetostearyl alcohol into an oil phase pot, stirring and mixing, heating to 75-80 ℃, and stirring and mixing until the mixture is completely dissolved to serve as an oil phase;
b. adding propylene glycol and sodium hyaluronate into a beaker, and stirring and mixing uniformly for later use;
c. adding the water phase component, the propylene glycol and sodium hyaluronate mixed solution into a water phase pot, stirring at normal temperature until the water phase component, the propylene glycol and the sodium hyaluronate mixed solution are completely dissolved, adding the acryloyl dimethyl ammonium taurate/VP copolymer after the water phase component, uniformly stirring, injecting steam, heating to 80-85 ℃, and keeping the temperature for 5-10 minutes;
d. adding propylene glycol dicaprate, octyl dodecanol xyloside and octyl dodecanol into the oil phase in the step a, and uniformly stirring for later use;
e. adding hydroxyacetophenone into the water phase pot in the step c, and stirring uniformly for later use;
f. respectively adding 85-90% of the water phase obtained in the step e and all the oil phase obtained in the step d into an emulsifying and stirring pot for emulsification, and controlling the temperature to be 80-85 ℃;
g. after the reaction in the step f is carried out for 8-10 minutes, adding the residual 10-15% of water phase, and starting to shear the solution in the emulsifying pot, wherein the shearing speed is 2800r/min-3880r/min, and the shearing time is 5-6 minutes;
h. and g, after the shearing in the step g is finished, injecting cooling water to cool the solution, after cooling to below 38 ℃, adding the aureobasidium pullulans/barley seed fermentation product filtrate, uniformly stirring, discharging, and sealing and storing.
2. The method of claim 1, wherein the emulsification vessel is preheated by injecting steam before step f.
3. The method of claim 1, wherein the stirring time for the dissolution of the aqueous phase in step c is 10 minutes to 15 minutes.
4. The method of claim 1, wherein the rotation speed of the emulsifying pot is 20-40 r/min and the vacuum pressure is 0.25-0.35 mpa in step f.
5. The method of claim 1, wherein the skin care product has a PH of 5.5 to 7.4.
6. The method for preparing a skin care product according to claim 1, wherein the vegetable oil is 2 to 10 parts by weight, the propylene glycol dicaprate is 2 to 5 parts by weight, the emulsifier is 1 to 3 parts by weight, the isostearyl alcohol is 1 to 5 parts by weight, the cetearyl alcohol is 1 to 3 parts by weight, the ammonium acryloyldimethyl taurate/VP copolymer is 1 to 3 parts by weight, the octyldodecanol xyloside is 1 to 3 parts by weight, the octyldodecanol is 1 to 2 parts by weight, the p-hydroxyacetophenone is 0.3 to 1.0 part by weight, the fermentation product filtrate of the Brevibacterium pullulanase/barley seeds is 1 to 5 parts by weight, the propylene glycol is 1 to 5 parts by weight, the sodium hyaluronate is 0.01 to 0.3 part by weight, the aqueous phase component includes glycerin, butylene glycol, and deionized water.
7. The method for preparing a skin care product according to claim 6, wherein the aureobasidium pullulans comprises, in mass percent: 35 to 45 percent of potato and 55 to 65 percent of barley seed.
8. The method for preparing skin care product according to claim 7, wherein the potato and the barley seeds are inoculated with yeast enzyme for fermentation treatment.
9. The method of claim 6, wherein the sodium hyaluronate has a molecular weight of 130 ten thousand.
10. The method of claim 6, wherein the emulsifier has a polycrystalline structure.
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| KR101449282B1 (en) * | 2013-05-14 | 2014-10-08 | 가천대학교 산학협력단 | Composition for improving skin wrinkle and skin moisturing comprising Barley fermented by Pichia jadinii and Aureobasidium pullulans bacteria |
| KR20160039972A (en) * | 2014-10-02 | 2016-04-12 | 샘표식품 주식회사 | Functional cosmetic composition comprising complex ferment consisting of soybean and barley |
| CN107496231A (en) * | 2017-08-28 | 2017-12-22 | 广州市馨雨化妆品有限公司 | A kind of skin care compositions and preparation method thereof |
| CN109875931A (en) * | 2019-03-19 | 2019-06-14 | 广东芭薇生物科技股份有限公司 | It is a kind of to have effects that the cosmetic additive agent of antipollution and its cosmetics |
| CN111249187A (en) * | 2018-12-03 | 2020-06-09 | 西安博鸿生物技术有限公司 | Wrinkle-removing eye cream and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| KR101449282B1 (en) * | 2013-05-14 | 2014-10-08 | 가천대학교 산학협력단 | Composition for improving skin wrinkle and skin moisturing comprising Barley fermented by Pichia jadinii and Aureobasidium pullulans bacteria |
| KR20160039972A (en) * | 2014-10-02 | 2016-04-12 | 샘표식품 주식회사 | Functional cosmetic composition comprising complex ferment consisting of soybean and barley |
| CN107496231A (en) * | 2017-08-28 | 2017-12-22 | 广州市馨雨化妆品有限公司 | A kind of skin care compositions and preparation method thereof |
| CN111249187A (en) * | 2018-12-03 | 2020-06-09 | 西安博鸿生物技术有限公司 | Wrinkle-removing eye cream and preparation method thereof |
| CN109875931A (en) * | 2019-03-19 | 2019-06-14 | 广东芭薇生物科技股份有限公司 | It is a kind of to have effects that the cosmetic additive agent of antipollution and its cosmetics |
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