CN109875931A - It is a kind of to have effects that the cosmetic additive agent of antipollution and its cosmetics - Google Patents
It is a kind of to have effects that the cosmetic additive agent of antipollution and its cosmetics Download PDFInfo
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Abstract
Have effects that the cosmetic additive agent of antipollution and its cosmetics the invention discloses a kind of, it is intended to provide a kind of attachment that can effectively reduce pollutant to skin, protect Skin Cell, resist the infringement of environmental contaminants, and have anti-inflammatory, it repairs, the cosmetic additive agent releived and other effects, technical points are, this has effects that the cosmetic additive agent of antipollution includes the component of following parts by weight: 3~12 parts of water shield leaf extract, 1~10 part of summer oak root extract, 1~7 part of seed extract of wing seed Moringa, 2~8 parts of grass green salicornia europaeal extract, 1~6 part of Aureobasidium pullulans tunning, 2~7 parts of ginkgo biloba p.e；Cosmetic additive agent of the present invention can be used in cosmetics, enhances skin barrier, excellent isolation and defense function are played to skin, is had a good application prospect；Belong to cosmetic technical field.
Description
Technical field
The invention discloses a kind of cosmetic additive agents, specifically, being that a kind of cosmetics with antipollution add
Add agent and cosmetics, belongs to cosmetic technical field.
Background technique
In recent years, with the development that global industry and urbanization process are advanced by leaps and bounds, environmental pollution especially atmosphere is dirty
Increasingly severe, and physiologic barrier of the skin as human body is contaminated, the first line of defence of all kinds of pollution sources is resistant to.Not only breathing is inhaled
The pollution sources entered can hurt skin, and the substance of many topical applications can be absorbed into internal cell or tissue by skin, break
Bad skin barrier function.
Currently, the air pollutants harmful to human health include dust suspension, particle (PM10, PM2.5), polycyclic virtue
Hydrocarbon (PAHs), ozone, nitrogen oxides, oxysulfide and oxycarbide etc., wherein PM2.5 is a kind of very important skin invasion
Person, its surface area is big, activity is strong, has tiny porous structure, is easier to subsidiary poisonous and harmful substances, such as: PAHs, a huge sum of money
Category, microorganism etc., and PM2.5 cannot penetrate skin, be easy to be attached to skin surface and constantly discharge adsorbed poisonous and harmful
Substance, these harmful substances can enter deep skin by pore, destroy skin health cell, lead to skin aging, and cause
A series of skin problems such as allergy, dermatitis, color spot.In addition to air pollution, ultraviolet line pollution will also result in skin lesion, UVA
Penetration power is very strong, and can go directly dermal layer of the skin, elastomer and collagen fabric is destroyed, by skin tanning, to the wound of skin
Evil property is maximum；UVB can be absorbed by stratospheric ozone, caused to shine and injured that skin is red, swollen, hot, pain, and serious person can also get blister
Or decortication.For a long time by the pollution of ultraviolet light, can make skin aging relaxation, it is dry it is coarse, generate wrinkle, follow the string, is black
Pigementation causes dermatitis, or even can also cause cutaneum carcinoma.
Therefore, resistant to pollution cosmetics first have to the adherency of the pollutants to skin such as isolation PM2.5, dust, polycyclic aromatic hydrocarbon,
The pollution particle on skin is removed, injury of the pollutant to skin is protected, it is also contemplated that light pollution bring skin is encroached on, skin
It is chronically under pollution environment, will lead to the problems such as skin barrier is impaired, and exacerbation skin is sensitive, initiation skin inflammation.And it is current
Pollution sources cannot be resisted effectively to resistant to pollution cosmetics from many aspects, or cannot be resisted well while to antipollution
Inflammation is releived, and skin barrier is repaired, and as people's consciousness anti-pollution to skin is gradually increased, for protective cosmetics
Demand is also constantly expanding, and therefore, developing one kind effectively antipollution cosmetic additive agent can be used in cosmetics just seem
It is extremely important.
Summary of the invention
Has effects that the cosmetic additive agent of antipollution the object of the present invention is to provide a kind of, which can have
Effect reduces attachment of the pollutant to skin, protects Skin Cell, and resisting air pollution bring PAHs, heavy metal, dust etc. has
Phenomena such as malicious harmful substance and ultraviolet light pollution bring skin aging, and have it is anti-inflammatory, repair, releive and other effects；It is answered
For skin barrier can be enhanced in cosmetics, excellent isolation and defense function are played to skin, delaying skin aging improves
The problems such as skin splash, inflammation, allergy.
First technical solution provided by the present application is such that
It is a kind of to have effects that the cosmetic additive agent of antipollution, the component comprising following parts by weight: water shield leaf extract 3~
12 parts, 1~10 part of summer oak root extract, 1~7 part of wing seed Moringa seed extract, 2~8 parts of grass green salicornia europaeal extract, budding it is short
Obstruct 1~6 part of mould tunning, 2~7 parts of ginkgo biloba p.e.
Further, which further includes 2~6 parts of edelweiss extract, Radix Mirabilis extract 1~5
Part；
Further, which further includes high mountain flower of Radix Scutellariae/4~8 parts of leaf/stem extraction.
Preferably, which includes the component of following parts by weight: 5~9 parts of water shield leaf extract, summer oak root mention
Take 3~8 parts of object, 3~6 parts of wing seed Moringa seed extract, 4~7 parts of grass green salicornia europaeal extract, Aureobasidium pullulans tunning 2
~5 parts, 3~6 parts of ginkgo biloba p.e；
It is highly preferred that the cosmetic additive agent includes the component of following parts by weight: 6~8 parts of water shield leaf extract, Xia Yue
5~7 parts of root extract, 4~5 parts of wing seed Moringa seed extract, 5~6 parts of grass green salicornia europaeal extract, Aureobasidium pullulans fermentation produce
3~4 parts of object, 4~5 parts of ginkgo biloba p.e, 3~5 parts of edelweiss extract, 2~4 parts of Radix Mirabilis extract；
It is highly preferred that the cosmetic additive agent includes the component of following parts by weight: 6~8 parts of water shield leaf extract, Xia Yue
5~7 parts of root extract, 4~5 parts of wing seed Moringa seed extract, 5~6 parts of grass green salicornia europaeal extract, Aureobasidium pullulans fermentation produce
3~4 parts of object, 4~5 parts of ginkgo biloba p.e, 4~5 parts of edelweiss extract, 3~4 parts of Radix Mirabilis extract, high mountain are yellow
5~7 parts of a kind of reed mentioned in ancient books flower/leaf/stem extraction.
Second technical solution provided by the invention is:
Containing the above-mentioned cosmetics with the cosmetic additive agent of antipollution, the cosmetics are lotion, essence, face
Frost, toner, make-up remover, gel, facial mask etc..In production, the selection of other components and preparation process can be according in cosmetics
Routine operation in this field carries out, and has effects that the cosmetic additive agent of antipollution accounts for the 1~10% of cosmetics gross mass.
Compared with prior art, the device have the advantages that it is as follows:
(1) both water shield leaf extract, summer oak root extract are combined and can effectively be prevented in technical solution provided by the invention
Aromatic hydrocarbon receptor (AhR) in BaP (representative substances of PAHs) and Skin Cell combines, and avoids the expression of CYP1A1 enzyme, supports
Anti- air pollution bring PAHs protects cell activity, while having very strong polyphenoils clear active oxygen and active nitrogen
Except activity, there is very strong affinity interaction to metal, protect the skin against the nocuousness such as ozone, nitrogen oxides, oxysulfide, heavy metal
Substance, and the back side of water shield leaf can secrete a kind of mucus of similar agar, this mucus is rich in carbohydrate, can be formed in skin surface
Layer protecting film locks more juicy, has moisturizing, anti-inflammatory effect；Wing seed Moringa seed extract is rich in protein isoreactivity
Ingredient, this is a kind of natural cation micro molecule albumen, and has lotus-effect, not only can be reduced pollutant in skin surface
Attachment, moreover it is possible to the murder by poisoning to preventing from heavy metal to Skin Cell, three collaboration plays the role of protection pollution, purification skin.
(2) Aureobasidium pullulans tunning is rich in Aureobasidium pullulans polysaccharide in technical solution provided by the invention, it has
Excellent film forming has very strong gas barrier property to oxygen, nitrogen, but have stronger penetrability in the film that skin surface is formed；Grass
Green salicornia europaeal extract is rich in glycine betaine, minerals, amino acid isoreactivity ingredient, can promote hyaluronic acid, ceramide synthesis
The synthesis of enzyme -3 and silk polyprotein, prevents water loss, provides skin better moisturizing effect, and can be improved and turn paddy ammonia
The synthesis of amidase -1 promotes the maturation of hornification coating, repairs damaged cell, Aureobasidium pullulans tunning, grass green salt angle
Careless extract, the collaboration of water shield leaf extract can form reticular structure in skin surface, serve as aqueous protective barrier, block contaminants
Absorption and infiltration to skin, and discomfort is dried caused by effectively releiving because of pollutant, it, can be effective with other compositions scientific composition
The absorption of the harmful substances such as PM2.5 in air, dust, heavy metal on the skin is resisted, prevents environmental contaminants to the wound of skin
Evil reaches enhancing skin barrier, improves cell viability, is effective against the effect of pollution.
(3) in technical solution provided by the invention edelweiss extract contain a large amount of 2-[(3S)-3-hydroxybutanate, chlorogenic acid and
Luteolin derivative can stimulate glutamine transaminage -1, involurin level to increase, enhance hornification coating, stimulate pocket
The gene expression of first albumen, small prolin rich proteins, Keratin 1 and Keratin 10 provides powerful protection and regeneration skin
The ability of barrier, and 2-[(3S)-3-hydroxybutanate has brilliant anti-oxidant, anti-inflammatory, DNA protection feature, can reduce the death of Skin Cell；
In conjunction with Radix Mirabilis extract can effectively prevent skin sensitivity reaction, mitigate environmental pollution caused by chafing, it is general it is red, itch
Phenomenon, with water shield leaf extract, summer oak root extract, wing seed Moringa seed extract, grass green salicornia europaeal extract, Aureobasidium pullulans
Tunning prescription helps skin to resist environment, has the function that repair sensitive skin, anti-inflammatory.
(4) high mountain flower of Radix Scutellariae/leaf/stem extraction, ginkgo biloba p.e can absorb UAV in technical solution provided by the invention
And UVB, cell membrane damage caused by mitigating because of ultraviolet light irradiation prevent infringement of the light pollution to skin, reach anti-aging, dispel
The effect of spot cooperates with the injury for being effective against multiple pollutant to skin with other components, protects Skin Cell, enhances skin
Barrier plays excellent isolation and defense function to skin, and then the problems such as improvement skin aging, color spot, inflammation, allergy.
Specific embodiment
The following is a clear and complete description of the technical scheme in the embodiments of the invention, it is clear that described embodiment
Only a part of the embodiments of the present invention, rather than whole embodiments.For not specifically specified technological parameter or condition,
It can refer to routine techniques progress.
Raw material used in the present invention is bought by commercial channel.Wherein, the buying of water shield leaf extract is good in Guangzhou hundred
Rich Co., Ltd, the buying of summer oak root extract in Guangzhou Bo Chi Biotechnology Co., Ltd, the buying of wing seed Moringa seed extract in
Miao Sen limited liability company, grass green salicornia europaeal extract purchase Yu Laiyu enterprise group, the buying of Aureobasidium pullulans tunning in
Weigh Industrial Co., Ltd. in Shanghai million, ginkgo biloba p.e buying in Shanghai Jia Ye Industrial Co., Ltd., edelweiss extract,
In Guangzhou Run Pei Chemical Co., Ltd., Radix Mirabilis extract buying is raw in Guangzhou Austria source for high mountain flower of Radix Scutellariae/leaf/stem extraction buying
Object Science and Technology Ltd..
Embodiment 1
It is a kind of to have effects that the cosmetic additive agent of antipollution, the component comprising following parts by weight: water shield leaf extract 3
Part, 1 part of summer oak root extract, 1 part of wing seed Moringa seed extract, 2 parts of grass green salicornia europaeal extract, Aureobasidium pullulans tunning
1 part, 2 parts of ginkgo biloba p.e.
Embodiment 2
It is a kind of to have effects that the cosmetic additive agent of antipollution, the component comprising following parts by weight: water shield leaf extract 5
Part, 3 parts of summer oak root extract, 3 parts of wing seed Moringa seed extract, 4 parts of grass green salicornia europaeal extract, Aureobasidium pullulans tunning
2 parts, 3 parts of ginkgo biloba p.e.
Embodiment 3
It is a kind of to have effects that the cosmetic additive agent of antipollution, the component comprising following parts by weight: water shield leaf extract 9
Part, 8 parts of summer oak root extract, 6 parts of wing seed Moringa seed extract, 7 parts of grass green salicornia europaeal extract, Aureobasidium pullulans tunning
5 parts, 6 parts of ginkgo biloba p.e.
Embodiment 4
It is a kind of to have effects that the cosmetic additive agent of antipollution, the component comprising following parts by weight: water shield leaf extract 12
Part, 10 parts of summer oak root extract, 7 parts of wing seed Moringa seed extract, 8 parts of grass green salicornia europaeal extract, Aureobasidium pullulans fermentation produce
6 parts of object, 7 parts of ginkgo biloba p.e.
Embodiment 5
It is a kind of to have effects that the cosmetic additive agent of antipollution, the component comprising following parts by weight: water shield leaf extract 3
Part, 1 part of summer oak root extract, 1 part of wing seed Moringa seed extract, 2 parts of grass green salicornia europaeal extract, Aureobasidium pullulans tunning
1 part, 2 parts of ginkgo biloba p.e, 2 parts of edelweiss extract, 1 part of Radix Mirabilis extract.
Embodiment 6
It is a kind of to have effects that the cosmetic additive agent of antipollution, the component comprising following parts by weight: water shield leaf extract 6
Part, 5 parts of summer oak root extract, 4 parts of wing seed Moringa seed extract, 5 parts of grass green salicornia europaeal extract, Aureobasidium pullulans tunning
3 parts, 4 parts of ginkgo biloba p.e, 3 parts of edelweiss extract, 2 parts of Radix Mirabilis extract.
Embodiment 7
It is a kind of to have effects that the cosmetic additive agent of antipollution, the component comprising following parts by weight: water shield leaf extract 8
Part, 7 parts of summer oak root extract, 5 parts of wing seed Moringa seed extract, 6 parts of grass green salicornia europaeal extract, Aureobasidium pullulans tunning
4 parts, 5 parts of ginkgo biloba p.e, 5 parts of edelweiss extract, 4 parts of Radix Mirabilis extract.
Embodiment 8
It is a kind of to have effects that the cosmetic additive agent of antipollution, the component comprising following parts by weight: water shield leaf extract 12
Part, 10 parts of summer oak root extract, 7 parts of wing seed Moringa seed extract, 8 parts of grass green salicornia europaeal extract, Aureobasidium pullulans fermentation produce
6 parts of object, 7 parts of ginkgo biloba p.e, 6 parts of edelweiss extract, 5 parts of Radix Mirabilis extract.
Embodiment 9
It is a kind of to have effects that the cosmetic additive agent of antipollution, the component comprising following parts by weight: water shield leaf extract 3
Part, 1 part of summer oak root extract, 1 part of wing seed Moringa seed extract, 2 parts of grass green salicornia europaeal extract, Aureobasidium pullulans tunning
1 part, 2 parts of ginkgo biloba p.e, high mountain flower of Radix Scutellariae/4 parts of leaf/stem extraction.
Embodiment 10
It is a kind of to have effects that the cosmetic additive agent of antipollution, the component comprising following parts by weight: water shield leaf extract 5
Part, 3 parts of summer oak root extract, 3 parts of wing seed Moringa seed extract, 4 parts of grass green salicornia europaeal extract, Aureobasidium pullulans tunning
2 parts, 3 parts of ginkgo biloba p.e, high mountain flower of Radix Scutellariae/5 parts of leaf/stem extraction.
Embodiment 11
It is a kind of to have effects that the cosmetic additive agent of antipollution, the component comprising following parts by weight: water shield leaf extract 9
Part, 8 parts of summer oak root extract, 6 parts of wing seed Moringa seed extract, 7 parts of grass green salicornia europaeal extract, Aureobasidium pullulans tunning
5 parts, 6 parts of ginkgo biloba p.e, high mountain flower of Radix Scutellariae/7 parts of leaf/stem extraction.
Embodiment 12
It is a kind of to have effects that the cosmetic additive agent of antipollution, the component comprising following parts by weight: water shield leaf extract 12
Part, 10 parts of summer oak root extract, 7 parts of wing seed Moringa seed extract, 8 parts of grass green salicornia europaeal extract, Aureobasidium pullulans fermentation produce
6 parts of object, 7 parts of ginkgo biloba p.e, high mountain flower of Radix Scutellariae/8 parts of leaf/stem extraction.
Embodiment 13
It is a kind of to have effects that the cosmetic additive agent of antipollution, the component comprising following parts by weight: water shield leaf extract 3
Part, 1 part of summer oak root extract, 1 part of wing seed Moringa seed extract, 2 parts of grass green salicornia europaeal extract, Aureobasidium pullulans tunning
1 part, 2 parts of ginkgo biloba p.e, 2 parts of edelweiss extract, 1 part of Radix Mirabilis extract, high mountain flower of Radix Scutellariae/leaf/stem extraction
4 parts of object.
Embodiment 14
It is a kind of to have effects that the cosmetic additive agent of antipollution, the component comprising following parts by weight: water shield leaf extract 6
Part, 5 parts of summer oak root extract, 4 parts of wing seed Moringa seed extract, 5 parts of grass green salicornia europaeal extract, Aureobasidium pullulans tunning
3 parts, 4 parts of ginkgo biloba p.e, 4 parts of edelweiss extract, 3 parts of Radix Mirabilis extract, high mountain flower of Radix Scutellariae/leaf/stem extraction
5 parts of object.
Embodiment 15
It is a kind of to have effects that the cosmetic additive agent of antipollution, the component comprising following parts by weight: water shield leaf extract 8
Part, 7 parts of summer oak root extract, 5 parts of wing seed Moringa seed extract, 6 parts of grass green salicornia europaeal extract, Aureobasidium pullulans tunning
4 parts, 5 parts of ginkgo biloba p.e, 5 parts of edelweiss extract, 4 parts of Radix Mirabilis extract, high mountain flower of Radix Scutellariae/leaf/stem extraction
7 parts of object.
Embodiment 16
It is a kind of to have effects that the cosmetic additive agent of antipollution, the component comprising following parts by weight: water shield leaf extract 12
Part, 10 parts of summer oak root extract, 7 parts of wing seed Moringa seed extract, 8 parts of grass green salicornia europaeal extract, Aureobasidium pullulans fermentation produce
6 parts of object, 7 parts of ginkgo biloba p.e, 6 parts of edelweiss extract, 5 parts of Radix Mirabilis extract, high mountain flower of Radix Scutellariae/leaf/stem mention
Take 8 parts of object.
In order to prove effect of the invention, the comparative experiments example of the application is given below:
Comparative example 1
It is a kind of to have effects that the cosmetic additive agent of antipollution, the component comprising following parts by weight: water shield leaf extract 5
Part, 3 parts of wing seed Moringa seed extract, 4 parts of grass green salicornia europaeal extract.
Comparative example 2
It is a kind of to have effects that the cosmetic additive agent of antipollution, the component comprising following parts by weight: water shield leaf extract 5
Part, 3 parts of summer oak root extract, 2 parts of Aureobasidium pullulans tunning.
Comparative example 3
It is a kind of to have effects that the cosmetic additive agent of antipollution, the component comprising following parts by weight: summer oak root extract 5
Part, 4 parts of wing seed Moringa seed extract, 3 parts of ginkgo biloba p.e, 5 parts of grass green salicornia europaeal extract, edelweiss extract 3
Part.
Comparative example 4
It is a kind of to have effects that the cosmetic additive agent of antipollution, the component comprising following parts by weight: water shield leaf extract 8
Part, 7 parts of summer oak root extract, 5 parts of ginkgo biloba p.e, 4 parts of Aureobasidium pullulans tunning, 4 parts of Radix Mirabilis extract.
Comparative example 5
It is a kind of to have effects that the cosmetic additive agent of antipollution, the component comprising following parts by weight: summer oak root extract 5
Part, 4 parts of wing seed Moringa seed extract, 3 parts of ginkgo biloba p.e, 4 parts of edelweiss extract, high mountain flower of Radix Scutellariae/leaf/stem mention
Take 5 parts of object.
Comparative example 6
It is a kind of to have effects that the cosmetic additive agent of antipollution, the component comprising following parts by weight: water shield leaf extract 6
Part, 4 parts of wing seed Moringa seed extract, 4 parts of ginkgo biloba p.e, 3 parts of Radix Mirabilis extract, high mountain flower of Radix Scutellariae/leaf/stem extraction
5 parts.
Comparative example 7
The a certain of purchase commercially available has effects that the lotion of antipollution.
Comparative example 8
Only contain emulsion matrix.
The cosmetic additive agent the preparation method comprises the following steps: pressing embodiment 1~16, any one group of weight number claims in comparative example 1~6
Take each component, be uniformly mixed at normal temperature to get.
Embodiment 1~16, the application method of any one group of cosmetic additive agent, is by any one group of change in comparative example 1~6
Cosmetic additive is added in cosmetics, the cosmetic additive agent with antipollution account for cosmetics gross mass 1~
10%.
The present invention has effects that the cosmetic additive agent of antipollution is added in cosmetics, can be according to preparing the normal of cosmetics
Technique and auxiliary material are advised, the skin protection cosmetics such as lotion, essence, face cream, toner, make-up remover, gel, facial mask are prepared into.It is producing
When, the selection of other components can be carried out according to the routine operation in this field in cosmetics.
In order to better illustrate the present invention the advantages of, is given below the present invention and provides the experiment effect of technical solution:
1, adsorbing powder dust is tested
1) test sample: by embodiment 1~16, the cosmetic additive agent of comparative example 1~6 is added to ordinary emulsion external application base
Resulting test sample is prepared in matter, wherein have effects that the cosmetic additive agent of antipollution accounts for the 5% of lotion gross mass, and
The lotion of comparative example 7 and 8.
2) test method: selection road assists diligent personnel 115, is randomly divided into 23 groups (every group 5), with hand cleanser by both hands
It cleans up, is dried with paper handkerchief.Every group of personnel smear the lotion of comparative example 8 on about 2 square centimeters of left forearm of area
Matrix 0.2g smears other each group test samples 0.2g on about 2 square centimeters of right forearm of area.Allow them on road side
Under being glued the dust on forearm with 3M adhesive tape after upper 4 hours on duty, weighing is averaged.Test result is shown in Table 1.
1 adsorbing powder dust test result of table
| Sample | Left forearm Dust Capacity/g | Right forearm Dust Capacity/g | Slip/% |
| Embodiment 1 | 0.0062 | 0.0024 | 61.22% |
| Embodiment 2 | 0.0048 | 0.0018 | 62.89% |
| Embodiment 3 | 0.0075 | 0.0027 | 63.34% |
| Embodiment 4 | 0.0053 | 0.0019 | 63.48% |
| Embodiment 5 | 0.0068 | 0.0024 | 64.05% |
| Embodiment 6 | 0.0084 | 0.0029 | 65.56% |
| Embodiment 7 | 0.0042 | 0.0014 | 65.85% |
| Embodiment 8 | 0.0055 | 0.0019 | 65.10% |
| Embodiment 9 | 0.0081 | 0.0026 | 67.77% |
| Embodiment 10 | 0.0090 | 0.0029 | 68.03% |
| Embodiment 11 | 0.0067 | 0.0021 | 68.28% |
| Embodiment 12 | 0.0088 | 0.0027 | 68.82% |
| Embodiment 13 | 0.0057 | 0.0016 | 71.95% |
| Embodiment 14 | 0.0064 | 0.0017 | 72.74% |
| Embodiment 15 | 0.0042 | 0.0011 | 73.13% |
| Embodiment 16 | 0.0084 | 0.0022 | 73.88% |
| Comparative example 1 | 0.0059 | 0.0034 | 42.13% |
| Comparative example 2 | 0.0073 | 0.0043 | 41.56% |
| Comparative example 3 | 0.0080 | 0.0045 | 43.75% |
| Comparative example 4 | 0.0077 | 0.0043 | 44.48% |
| Comparative example 5 | 0.0064 | 0.0034 | 46.25% |
| Comparative example 6 | 0.0069 | 0.0036 | 47.34% |
| Comparative example 7 | 0.0055 | 0.0034 | 38.90% |
It can be seen that from the experimental result of table 1 and smear the cream of addition cosmetic additive agent of the embodiment of the present invention in right forearm
After liquid, right forearm Dust Capacity is substantially reduced, and wherein dust reduction amount reaches 70% or more in embodiment 13~16, and smears comparison
Dust Capacity only reduces 38.90% after a certain commercially available resistant to pollution lotion of example 7, illustrates that cosmetic additive agent of the invention can obviously subtract
The absorption of pollutants on the skin such as few dust.After lotion using comparative example 1~6, dust reduction amount is relatively lower than using real
A lotion for cosmetic additive agent preparation is applied, illustrates that several extracts in cosmetic additive agent of the present invention are individually added to cream
Effect in liquid is obviously not so good as the effect being all added to nine kinds of ingredients of cosmetic additive agent of the present invention in lotion, and with this
The increase of species is extracted in invention, is reduced the effect that dust pollution object adheres on the skin and is also gradually increased, it follows that this hair
There are synergistic functions between the extract of bright offer, can preferably resist the contaminant particles such as PM2.5, dust.
2, skin barrier function is tested
1) test philosophy: normal skin has very strong barrier function, and extraneous harmful substance can be prevented to enter skin.Work as barrier
When function is damaged, access is just formed between horn cell, moisture scatters and disappears from access.Therefore, when skin barrier function weakens
Moisture percutaneously loses increase, otherwise reduces.Protective layer of skin is better, and moisture content is higher, the number of skin water loss TEWL
It is worth lower.This test judges the power of skin barrier function with percutaneous moisture loss (TEWL), to evaluate makeup of the present invention
Antipollution effect of product additive.
2) test sample: the cosmetic additive agent of embodiment 2,4,6,8,10,12,14,16, comparative example 1,3,5 is added
Resulting test sample is prepared into ordinary emulsion external-use substrate, wherein having effects that the cosmetic additive agent of antipollution accounts for lotion
The lotion of 5% and the comparative example 7 of gross mass.
3) test method: 130 female subjects of the more dry water shortage of selection face skin, the age 20~45 years old, with
Machine is divided into 13 groups, and every group of 10 people detect first three days, and any cosmetics are not used in face, and every group of subject takes 0.2g lotion respectively
It is applied on skin of face, is used continuously 28 days, the 29th, 30 day deactivated sample uses Tewameter respectively using once sooner or later daily
The TEWL value for being measured face after using sample the 1st day, the 31st day respectively, is repeated 5 times respectively, obtains average value.Test result
It is shown in Table 2.
The test of 2 skin barrier function of table
After the lotion that the experimental result of table 2 can be seen that using addition cosmetic additive agent of the embodiment of the present invention, skin
The change rate of skin water loss TEWL value reaches 60% or more, is higher than a certain commercially available resistant to pollution lotion of comparative example 7, illustrates this hair
Bright cosmetic additive agent has the function of enhancing skin barrier function.After lotion using comparative example 1,3,5, the change of TEWL value
Rate is relatively lower than the lotion prepared using embodiment cosmetic additive agent, illustrates to extract the increase of species with the present invention,
Reinforce skin barrier function, reduces the lost effect of moisture of skin and also gradually increase, it follows that extract provided by the invention
Between there are synergistic functions.
3, anti-inflammatory efficacy is tested
1) test philosophy: mice auricle swelling experiment is one kind of nonspecific inflammation model, mainly with chemical substance
Carry out inducing mouse ear swelling as proinflammatory agent, is commonly used to evaluate the anti-inflammatory activity of some synthesis compounds and effective ingredients in plant.
2) test sample: the cosmetic additive agent of embodiment 1,3,5,7,9,11,13,15, comparative example 2,4,6 is added to
Resulting test sample is prepared in ordinary emulsion external-use substrate, wherein it is total to have effects that the cosmetic additive agent of antipollution accounts for lotion
The lotion of 5% and the comparative example 7 of quality.
3) test method: taking male mice 130, (female mice can generate more estrogen, and estrogen has certain
Anti-inflammatory effect, should not be used in anti-inflammatory experiment), be randomly divided into 13 groups, every group 10, wherein one group (is smeared etc. for blank control
The physiological saline of dosage) group, remaining, which is organized, smears test sample, smears each test sample 30d, each 1g, last dose in advance
Auricle smears 30 μ L of dimethylbenzene and causes acute inflammation model outside auris dextra after 30min, and left ear does not apply to be compareed as normal ear.Apply two
It after toluene 1h, is put to death after taking blood, lays auricle in left and right ear same position with the punch of diameter 6mm, in claiming on assay balance
Quality is averaged, and calculates swelling and swelling inhibiting rate.Experimental result is shown in Table 3.
Wherein:
Auris dextra tablet quality-does not cause scorching left auricle quality after swelling=cause is scorching
Swelling inhibiting rate=(blank control group be averaged swelling-medication group be averaged swelling)/blank control group is averagely swollen
Expansibility × 100%
The test of 3 anti-inflammatory efficacy of table
Note: compared with the control group, *: P < 0.01 of *: P < 0.05, *.
It is a certain higher than comparative example 7 to can be seen that cosmetic additive agent swelling inhibiting rate of the invention from the experimental result of table 3
Commercially available resistant to pollution lotion illustrates that cosmetic additive agent of the present invention can substantially reduced mice caused by dimethylbenzene xylene auricle inflammatory swelling.Make
With the cosmetic additive agent of comparative example 2,4,6, its swelling inhibiting rate is relatively lower than embodiment, it was demonstrated that cosmetics addition of the invention
Agent, which rationally compounds, just has preferable anti-inflammatory efficacy.
4, anti-ultraviolet property is tested
1) test philosophy: sun protection factor SPF is an important parameter for measuring cosmetics uvioresistant performance, and spf value is higher,
Uvioresistant performance is stronger.
2) test sample: the sample in skin barrier function test is selected.
3) test method: with the spf value of the SPF analysis-e/or determining each sample of Labsphere company, respectively 1g
Test sample is evenly applied on the transparent PMMA plate of class skin quality of 5cm × 5cm, is then placed on dark place standing after 15 minutes, will
It is placed on its sun-proof performance of UV-2000S type ultraviolet ray transmissivity analysis-e/or determining, takes 10 different parts to be measured, takes it
Average value.Test result is shown in Table 4.
The test of 4 anti-ultraviolet property of table
It is a certain commercially available that the spf value that can be seen that cosmetic additive agent of the present invention from the experimental result of table 4 is higher than comparative example 7
Resistant to pollution lotion illustrates that cosmetic additive agent of the present invention has and supports anti-ultraviolet performance.The spf value of comparative example lotion is opposite
Lower than the lotion of embodiment, illustrate that better uvioresistant effect is played in cosmetic additive agent compounding collaboration of the present invention, slow down because
The problems such as UV-induced skin aging, melanin deposition, color spot.
5, BaP tests DNA Damage
1) test philosophy: the journey that comet can be detected effectively and the single, double chain notch of DNA damages in quantitative analysis cell
Degree, DNA is impaired more serious, and the chain rupture of generation and part are more, and length is also bigger, the DNA migrated under identical deposition condition
Just the more, the distance of migration is just longer for amount, and migrating the optical density of part or migration length by measurement DNA can measure individually
DNA Damage degree.
2) test sample: the sample in skin barrier function test is selected.
3) test method: using Human Keratinocytes as object, in vitro culture human body keratinocyte, each group adds respectively for this experiment
Culture 2h adds 10% BaP solution after entering test sample 2g, carries out comet afterwards for 24 hours, obtains DNA damage percentage,
BaP is reduced to the effect of cellular damage for evaluating cosmetic additive agent of the present invention.Test result is shown in Table 5.
5 BaP of table is to DNA Damage test result
It can be seen that the DNA damage that the Human Keratinocytes of cosmetic additive agent of the present invention are added from the experimental result of table 5
Percentage is less than comparative example 7, illustrates the infringement that cosmetic additive agent of the present invention is effective against BaP to Skin Cell.And add
The DNA damage percentage for entering the Human Keratinocytes of 1,3,5 cosmetic additive agent of comparative example is relatively higher than embodiment, illustrates this hair
Bright cosmetic additive agent compounding can preferably reduce injury of the pollutants such as polycyclic aromatic hydrocarbon to skin, reach protection Skin Cell
Effect.
In conclusion the present invention passes through water shield leaf extract, summer oak root extract, wing seed Moringa seed extract, grass green salt
Angle grass extract, Aureobasidium pullulans tunning, edelweiss extract, Radix Mirabilis extract, high mountain flower of Radix Scutellariae/leaf/stem
Synergistic effect between extract, ginkgo biloba p.e these types natural active products can effectively adjust and reduce of low pollution object to skin
Adhere to, resist the infringement of environmental contaminants, and have and releive, is anti-inflammatory, repair and other effects.
The above embodiment is a preferred embodiment of the present invention, but embodiments of the present invention are not by above-described embodiment
Limitation, other any changes, modifications, substitutions, combinations, simplifications made without departing from the spirit and principles of the present invention,
It should be equivalent substitute mode, be included within the scope of the present invention.
Claims (8)
1. a kind of have effects that the cosmetic additive agent of antipollution, which is characterized in that the component comprising following parts by weight: water shield leaf
3~12 parts of extract, 1~10 part of summer oak root extract, 1~7 part of wing seed Moringa seed extract, grass green salicornia europaeal extract 2~8
Part, 1~6 part of Aureobasidium pullulans tunning, 2~7 parts of ginkgo biloba p.e.
A kind of has effects that the cosmetic additive agent of antipollution 2. according to claim 1, which is characterized in that the makeup
Product additive also includes the component of following parts by weight: 2~6 parts of edelweiss extract, 1~5 part of Radix Mirabilis extract.
A kind of has effects that the cosmetic additive agent of antipollution 3. according to claim 1 or 2, which is characterized in that described
Cosmetic additive agent also includes the component of following parts by weight: high mountain flower of Radix Scutellariae/4~8 parts of leaf/stem extraction.
A kind of has effects that the cosmetic additive agent of antipollution 4. according to claim 1, which is characterized in that the makeup
Product additive includes the component of following parts by weight: 5~9 parts of water shield leaf extract, 3~8 parts of summer oak root extract, wing seed moringa seeds
3~6 parts of extract, 4~7 parts of grass green salicornia europaeal extract, 2~5 parts of Aureobasidium pullulans tunning, ginkgo biloba p.e 3~6
Part.
A kind of has effects that the cosmetic additive agent of antipollution 5. according to claim 2, which is characterized in that the makeup
Product additive includes the component of following parts by weight: 6~8 parts of water shield leaf extract, 5~7 parts of summer oak root extract, wing seed moringa seeds
4~5 parts of extract, 5~6 parts of grass green salicornia europaeal extract, 3~4 parts of Aureobasidium pullulans tunning, ginkgo biloba p.e 4~5
Part, 3~5 parts of edelweiss extract, 2~4 parts of Radix Mirabilis extract.
A kind of has effects that the cosmetic additive agent of antipollution 6. according to claim 3, which is characterized in that the makeup
Product additive includes the component of following parts by weight: 6~8 parts of water shield leaf extract, 5~7 parts of summer oak root extract, wing seed moringa seeds
4~5 parts of extract, 5~6 parts of grass green salicornia europaeal extract, 3~4 parts of Aureobasidium pullulans tunning, ginkgo biloba p.e 4~5
Part, 4~5 parts of edelweiss extract, 3~4 parts of Radix Mirabilis extract, high mountain flower of Radix Scutellariae/5~7 parts of leaf/stem extraction.
7. a kind of containing the cosmetics with the cosmetic additive agent of antipollution described in claim 1, which is characterized in that by
Have effects that the cosmetic additive agent of antipollution and common matrix are formed according to 1~10 ﹕ 99~90 of mass ratio.
8. according to claim 7 have effects that the cosmetics of antipollution, which is characterized in that the cosmetics are cream
One of liquid, essence, face cream, toner, make-up remover, gel, facial mask.
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| CN114146045A (en) * | 2021-11-12 | 2022-03-08 | 赣州澳丽尔化妆品有限公司 | Skin care product obtained by biological fermentation technology and preparation method thereof |
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