CN109157445A

CN109157445A - Skin matrix and the preparation method and application thereof with antipollution and anti-inflammatory efficacy

Info

Publication number: CN109157445A
Application number: CN201811042168.3A
Authority: CN
Inventors: 贺君玉; 孙云起; 孙怀庆; 裴运林; 聂艳峰; 金宇尧
Original assignee: Guangdong Marubi Biological Technology Co Ltd
Current assignee: Guangdong Marubi Biological Technology Co Ltd
Priority date: 2018-09-07
Filing date: 2018-09-07
Publication date: 2019-01-08
Anticipated expiration: 2038-09-07
Also published as: CN109157445B

Abstract

The skin matrix and the preparation method and application thereof with antipollution and anti-inflammatory efficacy that the invention discloses a kind of.Skin matrix provided by the invention mainly includes following components: 1,2- pentanediol 3~5%, butanediol 10~15%, wing seed Moringa seed extract 1~10%, Ganodenna Lucidum P.E 1~10%, licorice root extract 1~10%, Flos Nelumbinis extract 1~10%.Cell can be effectively protected in the skin matrix, resist external environmental, purify toxin, and deep layer cleaning pollution diminishes inflammation；The matrix in cosmetics, long-time service can clean skin prevent pore obstruction, diminish inflammation.Therefore, which can be added in the cosmetics such as lotion, cream, toner or Essence as raw material, supply nutrition for skin, have both antipollution and anti-inflammatory effect.

Description

Skin matrix and the preparation method and application thereof with antipollution and anti-inflammatory efficacy

Technical field

The present invention relates to the technical field of cosmetics, in particular to a kind of skin matrix with antipollution and anti-inflammatory efficacy And the preparation method and application thereof.

Background technique

Air pollution, also known as atmosphere pollution, according to the definition of International Organization for standardization (ISO), air pollution refer to due to Mankind's activity or natural process cause Cucumber to enter in atmosphere, show enough concentration, reach time enough, and because This compromises the phenomenon that the comfortable, healthy of the mankind, welfare or environment.In other words, as long as the existing amount of a certain substance, property And the time, enough to the mankind or other biological, the property person of having an impact, we can be called air pollutants, exist and make At phenomenon, be exactly air pollution.

With production and economic fast development, people's lives level is continuously improved, but living environment is also in disconnected evil Change.Suspended particulate substance has generally exceeded the standard in urban air, control pollution gets worse, sandstorm, haze, PM2.5, industrial waste gas, The increase of the pollutions such as vehicle exhaust and heavy metal, seriously threatens everyone health.If things go on like this skin will appear a series of Problem, such as skin is easy allergy, easy clogging of pores leads to the problem of a series of skin such as inflammation.Currently, we can not change The status of air pollution, but erosion of the outside contamination to skin can be resisted by scientific and effective measure, therefore, exploitation It is a with antipollution and the skin care item of anti-inflammatory two kinds of functions are very necessary.

Summary of the invention

The primary purpose of the present invention is that the shortcomings that overcoming the prior art and deficiency, provide a kind of with antipollution and anti-inflammatory The skin matrix of effect.

Another object of the present invention is to provide the preparation methods by above-mentioned skin matrix.

A further object of the present invention is to provide the applications of above-mentioned skin matrix.

The purpose of the invention is achieved by the following technical solution: a kind of skin matrix with antipollution and anti-inflammatory efficacy, Mainly include following component as mass fraction: 1,2- pentanediol 3~5%, butanediol 10~15%, wing seed moringa seeds extract Object 1~10%, Ganodenna Lucidum P.E 1~10%, licorice root extract 1~10%, Flos Nelumbinis extract 1~10%；Preferably, mainly Include following component as mass fraction: 1,2- pentanediol 3~5%, butanediol 12~15%, wing seed Moringa seed extract 2 ~8%, Ganodenna Lucidum P.E 2~8%, licorice root extract 2~8%, Flos Nelumbinis extract 2~8%；It is highly preferred that mainly including Component as mass fraction below: 1,2- pentanediol 4~5%, butanediol 12~14%, wing seed Moringa seed extract 3~ 7%, Ganodenna Lucidum P.E 3~7%, licorice root extract 3~7%, Flos Nelumbinis extract 3~7%.

The skin matrix with antipollution and anti-inflammatory efficacy also may include water；Or it is also protected comprising other function At least one of skin substance, preservative, pigment and essence ingredient and water.

The other function skin care substance includes moisturizing materials, whitening material, anti-wrinkle substance etc..

The dosage of the preservative, pigment and essence be it is appropriate, meet the relevant regulations such as country, industry.

The dosage of the water is surplus.

The preparation method of the above-mentioned skin matrix with antipollution and anti-inflammatory efficacy, comprising the following steps: by formula ratio 1,2- pentanediol, butanediol and water mix, and wing seed Moringa seed extract, Ganodenna Lucidum P.E, licorice root extract and lotus flower is added Extract mixes, obtains skin matrix；Preferably include following steps:

(1) 1,2- pentanediol, butanediol and water are mixed, is heated, heat preservation obtains clear solution, spare；

(2) clear solution for obtaining step (1) cools down, and wing seed Moringa seed extract, Ganodenna Lucidum P.E, licorice is added Extract and Flos Nelumbinis extract are uniformly mixed, obtain the skin matrix with antipollution and anti-inflammatory efficacy.

The temperature of heating described in step (1) is 85~90 DEG C；Preferably 85 DEG C.

The time of heat preservation described in step (1) is 20~30min；Preferably 30min.

The mode of stirring can be used in mixing described in step (1), and the speed of stirring is 300~400r/min.

The temperature of cooling described in step (2) is 35~40 DEG C；Preferably 38 DEG C.

Uniformly mixed mode described in step (2) preferably stirs, and the condition of stirring is preferred are as follows: mixing speed is 800~1000r/min, preferably 1000r/min；Mixing time is 5~10min, preferably 10min.

It is also preferable to include separating steps after the uniformly mixed step in step (2), to guarantee obtained product The homogeneity of system is more preferable.

The mode of filtering can be used in the separation, and filtering mesh number is 150~300 mesh；Preferably 200 mesh.

The above-mentioned skin matrix with antipollution and anti-inflammatory efficacy is preparing the application in cosmetics.

The cosmetics are functional cosmetics, it is typical but it is unrestricted for antipollution skin care item, it is anti-inflammatory skin care item, salubrious Skin care item and anti-acne skin care item.

A kind of cosmetics with antipollution and anti-inflammatory efficacy include the above-mentioned skin care base with antipollution and anti-inflammatory efficacy Matter.

The type of the cosmetics includes lotion, cream, toner and Essence etc..

Content of the skin matrix in the cosmetics is mass percent 20~30%.

The cosmetics with antipollution and anti-inflammatory efficacy, preferably comprise following component by mass percentage:

Component A: isooctadecanol/butanediol cocounut oil acid esters/ethyl cellulose 3~7%, isononyl isononanoate 1~5%, Australia Continent nut (Macadamia ternifolia) seed oil 1~5%, dimethyl silicone polymer 1~5%；

B component: glycerol 4~10%, butanediol 4~10%, acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters crosslinking are poly- Object 0.1~0.5% is closed, surplus is water；

Component C: triethanolamine 0.08~0.15%；

D component: sodium acrylate/sodium acryloyldimethyl taurate copolymers/isohexadecane/Polyoxyethylene Sorbitan Monooleate/water/ The smooth oleate 0.5~1.2% of sorb；

Component E: the skin matrix 20~30%, essence 0~appropriate.

Described is to meet the relevant regulations such as country, industry in right amount.

Content of the essence in the cosmetics is preferably mass percent 0.01~0.05%.

The water is preferably deionized water.

The preparation method of the cosmetics includes the following steps: to mix ingredient each in component A, obtains oily phase；By B Each ingredient mixes in component, obtains water phase；It is mutually mixed oily with water phase, carries out homogeneous；It is subsequently added into component C, homogeneous；D is added Component, then homogeneous；Component E is added, obtains cosmetics after homogeneous；Preferably, specifically comprise the following steps:

1) oily phase pot is added in each ingredient in component A, stirring is warming up to 85~90 DEG C, and heat preservation obtains oily phase；

2) water phase pot is added in each substance in B component, stirring is warming up to 85~90 DEG C, and heat preservation obtains water phase；

3) water phase is sucked into emulsion pot, mutually sucks emulsion pot for oily again after mixing evenly, keeps vacuum and mixing speed not Become, homogeneous；

4) component C, homogeneous are added in the homogeneous product that step 3) obtains；

5) D component, homogeneous are added in the homogeneous product that step 4) obtains；

6) 40~45 DEG C are cooled to after the completion of homogeneous, are stirred and evenly mixed after adding component E, homogeneous obtains cosmetics.

The speed of stirring described in step 1) is 800~1000r/min；Preferably 1000r/min.

The temperature of heating described in step 1) is preferably 85 DEG C.

The time of heat preservation described in step 1) is 5~10min；Preferably 10min.

The speed of stirring described in step 2) is 800~1000r/min；Preferably 1000r/min.

The temperature of heating described in step 2) is preferably 85 DEG C.

The time of heat preservation described in step 2) is 10~20min；Preferably 20min.

The speed of stirring described in step 3) is 600~800r/min；Preferably 600r/min.

The pressure of vacuum described in step 3) is -0.05~-0.08MPa；Preferably -0.05MPa.

The time of homogeneous described in step 3) is 3~5min；Preferably 5min.

The speed of homogeneous described in step 3) is 2000~3000r/min；Preferably 3000r/min.

The time of homogeneous described in step 4) is 3~5min；Preferably 3min.

The speed of homogeneous described in step 4) is 1000~2000r/min；Preferably 2000r/min.

The time of homogeneous described in step 5) is 3~5min；Preferably 3min.

The speed of homogeneous described in step 5) is 1000~2000r/min；Preferably 2000r/min.

The temperature of cooling described in step (6) is preferably 45 DEG C.

The time of stirring described in step (6) is 3~5min；Preferably 5min.

The speed of stirring described in step (6) is 600~800r/min；Preferably 600r/min.

The time of homogeneous described in step (6) is 1~3min；Preferably 1min.

The speed of homogeneous described in step (6) is 1000~2000r/min；Preferably 2000r/min.

Above-mentioned component A is oil phase and emulsifier, is water phase after B component mixing；Component C is neutralizer, can effectively neutralize A Component and B component realize the effect mixed well；D is thickener, plays the role of thickening and stabilising system.Since component E is Low temperature component, thus need in the preparation finally cool down after component E is added, can guarantee component E effective component and remaining at Divide and is sufficiently mixed uniformly, to reduce the loss of effective component.Inventor is by sequentially adding each component and by heating, specific speed Degree and the operations such as the stirring under the time, homogeneous make to be sufficiently mixed between each effective component, active constituent sufficiently discharges, and finally obtain Property stable homogeneous and the preferable cosmetics of quality.

The present invention has the following advantages and effects with respect to the prior art:

1. skin matrix selection wing seed Moringa seed extract, Ganodenna Lucidum P.E, licorice root extract and lotus flower of the invention Four kinds of functional components of extract, and cooperate with 1,2- pentanediol, butanediol and water, it, can by reasonable compatibility between each component It realizes synergistic effect, is effectively protected cell, resist external environmental, purify toxin, deep layer cleaning pollution is eliminated Inflammation etc..

It, can by heating, stirring and separation 2. the preparation method of skin matrix of the invention is simple, easy to operate Make to mix well between the effective component of each component, is conducive to active constituent and sufficiently discharges, it is final to obtain that property is uniform and quality Stable skin matrix product is suitable for standardized production and popularization and application.

3. skin matrix of the invention can be added to the cosmetics such as lotion, cream, toner or Essence as raw material In, nutrition is supplied for skin, has both antipollution and anti-inflammatory effect.

4. cosmetics of the invention can not only make cosmetics transdermal by skin by the skin matrix of addition certain content It absorbs, provides nutrition for skin, moreover it is possible to cosmetics be made to have both antipollution and anti-inflammatory effect.

5. the preparation method of cosmetics of the invention is simple, easy to operate, it can guarantee finally to obtain that property is uniform and matter Stable cosmetics are measured, standardized production and popularization and application are suitable for.

In the skin matrix that embodiment of the present invention provides.Skin matrix is applied in cosmetics, and long-time service can be clean Net skin prevents pore from blocking and diminishing inflammation.

Specific embodiment

Embodiment of the present invention is described in detail below in conjunction with embodiment, but those skilled in the art will It will be appreciated that following embodiments and embodiment are merely to illustrate the present invention, and it is not construed as limiting the scope of the invention.It is not specified Actual conditions person carries out according to conventional conditions or manufacturer's recommended conditions.Reagents or instruments used without specified manufacturer, It is the conventional products that can be obtained by commercially available purchase.

In the formula for the skin matrix that embodiment of the present invention provides:

Wing seed Moringa seed extract: the purchase of wing seed Moringa (MORINGA PTERYGOSPERMA) seed extract is certainly German BASF AG, the trade mark are Purisoft LS9726.

Chinese ganoderma lucidum (GANODERMA SINENSIS) extract, (partially red) yellow liquid are dissolved in water, index of refraction (20 DEG C): 1.370-1.420, opposite specific gravity (20 DEG C): 1.010-1.040, pH:4.0-6.0.Ganoderma lucidum is a kind of Chinese herbal medicine, usually quilt It is used as a kind of therapeutic agent for treating disease, the purposes based on it as traditional medicine, Chinese ganoderma lucidum (GANODERMA SINENSIS) extract is considered as a kind of safe cosmetic material.In the present invention, Chinese ganoderma lucidum (GANODERMA SINENSIS) the main purposes of extract is anti-inflammatory.In the present invention, Chinese ganoderma lucidum (GANODERMA SINENSIS) extract From Huzhou Jiamei, the trade mark is Ganodenna Lucidum P.E (GANODERMA EXTRACT) for purchase.

Licorice root extract, brown liquid, Radix Glycyrrhizae distinctive smell, pH:4.5-6.5.Licorice is rich in anti-oxidant Substance and antibacterial, anti-inflammatory substance, can infiltrate into deep skin, and go directly capillary.There is antibacterial, anti-inflammatory function in the present invention Effect.In the present invention, from domestic Wuhan great Hua great achievement company, the trade mark is licorice extract for licorice purchase.

Flos Nelumbinis extract, colourless transparent liquid, pH:5.0-7.0, opposite specific gravity (20 DEG C): 0.990-1.040 compares Weight (20 DEG C): 0.990-1.040, index of refraction (20 DEG C): 1.320-1.360.In the present invention, it is turned into antibacterial and antioxygen With.In the present invention, Flos Nelumbinis extract purchase wins well BIOLAND from hundred, and the trade mark is NELUMBO NUCIFERA FLOWER EXTRACT。

Optionally, the mass percent of 1,2- pentanediol it is typical but non-limiting be 3%, 3.5%, 4%, 4.5% or 5%.

Optionally, the mass percent of butanediol it is typical but non-limiting be 10%, 11%, 12%, 13%, 14% or 15%.

Optionally, it is 1% that the mass percent of wing seed Moringa seed extract is typical but non-limiting, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9% or 10%.

Optionally, the mass percent of Chinese ganoderma lucidum (GANODERMA SINENSIS) extract is typical but non-limiting is 1%, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9% or 10%.

Optionally, it is 1% that the mass percent of licorice root extract is typical but non-limiting, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9% or 10%.

Optionally, it is 1% that the mass percent of Flos Nelumbinis extract is typical but non-limiting, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9% or 10%.

In the present invention, water used is preferably deionized water.

In the main component of skin matrix, the dosage of water is surplus, refers to and removes in the raw material components of skin matrix of the present invention Go 1,2- pentanediol, butanediol, wing seed Moringa seed extract, Ganodenna Lucidum P.E, licorice root extract and lotus flower root extract and Surplus except optional other components is water, and water and 1,2- pentanediol, butanediol, wing seed Moringa seed extract, ganoderma lucidum are extracted The sum of object, licorice root extract and Flos Nelumbinis extract and the optional mass percent of other components are 100%.

In the preparation method for the skin matrix that embodiment of the present invention provides:

Optionally, the preparation method for the skin matrix that embodiment of the present invention provides, in step (1), heating temperature allusion quotation Type but it is non-limiting be 85 DEG C, 86 DEG C, 87 DEG C, 88 DEG C, 89 DEG C or 90 DEG C；Soaking time it is typical but it is non-limiting for 20min, 21min, 22min, 23min, 24min, 25min, 26min, 27min, 28min, 29min or 30min.

Optionally, in step (1), 1,2- pentanediol, butanediol and water can also be stirred when mixing, mixing speed It is typical but non-limiting for 300r/min, 310r/min, 320r/min, 330r/min, 340r/min, 350r/min, 360r/ Min, 370r/min, 380r/min, 390r/min or 400r/min.

Optionally, in step (2), temperature is 35~40 DEG C after cooling；And/or mixing speed is 800~1000r/ Min, mixing time are 5~10min；And/or separation, by the way of filtering, filtering mesh number is 150~250 mesh.

Optionally, in step (2), after cooling temperature it is typical but it is non-limiting be 35 DEG C, 36 DEG C, 37 DEG C, 38 DEG C, 39 DEG C Or 40 DEG C.

Optionally, in step (2), typical but non-limiting mixing speed is 800r/min, 820r/min, 840r/ Min, 850r/min, 870r/min, 900r/min, 920r/min, 940r/min, 950r/min, 970r/min or 1000r/ min；And/or mixing time is typical but non-limiting for 5min, 6min, 7min, 8min, 9min or 10min.

Optionally, in step (2), it is 150 mesh, 200 mesh, 250 mesh or 300 mesh that filtering mesh number is typical but non-limiting.

In the cosmetics that embodiment of the present invention provides:

Optionally, it is 20% that mass percent of the skin matrix in cosmetics is typical but non-limiting, 21%, 22%, 23%, 24%, 25%, 26%, 27%, 28%, 29% or 30%.

Queensland nut (MACADAMIA TERNIFOLIA) seed oil, the commercial goods of purchase have mildly, do not stimulate skin Skin, protect cell membrane and moisten, moisturizing the effect of.

Optionally, isooctadecanol/butanediol cocounut oil acid esters/ethyl cellulose mass percent is typical but non-limiting is 3%, 4%, 4.5%, 5%, 6% or 7%.

Optionally, it is 1%, 2%, 2.5%, 3%, 4% that the mass percent of isononyl isononanoate is typical but non-limiting Or 5%.

Optionally, the mass percent of Queensland nut (MACADAMIA TERNIFOLIA) seed oil is typical but non-limiting is 1%, 2%, 2.5%, 3%, 4% or 5%.

Optionally, it is 1% that the mass percent of dimethyl silicone polymer is typical but non-limiting, 2%, 2.5%, 3%, 4% or 5%.

Optionally, it is 4%, 5%, 6%, 8% or 10% that the mass percent of glycerol is typical but non-limiting.

Optionally, it is 4%, 5%, 6%, 8% or 10% that the mass percent of butanediol is typical but non-limiting.

Optionally, acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymer mass percent is typical but non- Restricted is 0.1%, 0.2%, 0.3%, 0.4% or 0.5%.

Optionally, it is 0.08%, 0.1%, 0.12%, 0.14% that the mass percent of triethanolamine is typical but non-limiting Or 0.15%.

Optionally, sodium acrylate/sodium acryloyldimethyl taurate copolymers/isohexadecane/Polyoxyethylene Sorbitan Monooleate/water/ It is 0.5%, 0.7%, 1.0% or 1.2% that the mass percent of the smooth oleate of sorb is typical but non-limiting.Optionally, essence Mass percent it is typical but it is non-limiting be 0.01%, 0.03% or 0.05%.

It, can be right by the way that the skin matrix of the present invention of certain content is added in the cosmetics that embodiment of the present invention provides Skin realizes antipollution and anti-inflammatory effect, while cooperating with other raw materials, additionally it is possible to realize good replenishing water and preserving moisture, moisten The effect of skin skin lightening.

In the preparation method for the cosmetics that embodiment of the present invention provides:

Homogeneous is also referred to as homogenized, be make dispersion micronized in suspension (or emulsion) system, homogenization it is processed Journey, it is this to handle while plaing a part of to reduce dispersion scale and improving dispersion distributing homogeneity.

By sequentially adding each component and by operations such as heating, stirring and homogeneous, can make to fill between each effective component Divide mixing, is conducive to active constituent and sufficiently discharges, obtain the cosmetics of stable homogeneous.

Optionally, in step 1), mixing speed is 800~1000r/min；Mixing speed it is typical but it is non-limiting can be with For 800r/min, 850r/min, 900r/min, 950r/min or 1000r/min.

Optionally, in step 1), warming temperature is typical but non-limiting be 85 DEG C, 86 DEG C, 87 DEG C, 88 DEG C, 89 DEG C or 90℃。

Optionally, in step 1), soaking time is 5~10min；Soaking time it is typical but it is non-limiting for 5min, 6min, 7min, 8min, 9min or 10min.

Optionally, in step 2), mixing speed is 800~1000r/min；Mixing speed it is typical but it is non-limiting can be with For 800r/min, 850r/min, 900r/min, 950r/min or 1000r/min.

Optionally, in step 2), warming temperature is typical but non-limiting be 85 DEG C, 86 DEG C, 87 DEG C, 88 DEG C, 89 DEG C or 90℃。

Optionally, in step 2), soaking time is 10~20min；Soaking time it is typical but it is non-limiting for 10min, 11min, 12min, 13min, 14min, 15min, 16min, 17min, 18min, 19min or 20min.

Optionally, in step 3), mixing speed is 600~800r/min；Mixing speed is typical but non-limiting to be 600r/min, 650r/min, 700r/min, 750r/min or 800r/min.

Optionally, in step 3), pressure is -0.05~-0.08MPa under vacuum；Pressure is typical but unrestricted under vacuum Property be -0.05MPa, -0.06MPa, -0.07MPa or -0.08MPa.

Optionally, in step 3), the typical but non-limiting time of homogeneous is 3min, 4min or 5min；Homogeneous speed For 2000~3000r/min；Typical but non-limiting homogeneous speed is 2000r/min, 2500r/min or 3000r/min.

Optionally, in step 4), the typical but non-limiting time of homogeneous is 3min, 4min or 5min；Homogeneous speed For 1000~2000r/min；Homogeneous speed it is typical but it is non-limiting for 1000r/min, 1200r/min, 1500r/min, 1800r/min or 2000r/min.

Optionally, in step 5), the typical but non-limiting time of homogeneous is 3min, 4min or 5min；Homogeneous speed For 1000~2000r/min；Homogeneous speed it is typical but it is non-limiting for 1000r/min, 1200r/min, 1500r/min, 1800r/min or 2000r/min.

Optionally, in step 6), the mode of cooling can be cooled down using cold water, and temperature is typical but non-limiting after cooling It is 40 DEG C, 41 DEG C, 42 DEG C, 43 DEG C, 44 DEG C or 45 DEG C.

Optionally, in step 6), mixing time typical case but non-limiting 3min, 4min or 5min；Mixing speed is 600 ~800r/min, typical but non-limiting mixing speed is 600min, 650min, 700min, 750min or 800r/min.

Optionally, in step 6), typical but non-limiting homogenizing time is 1min, 2min or 3min；Homogeneous speed is 1000~2000r/min；Typical but non-limiting homogeneous speed is 1000r/min, 1200r/min, 1500r/min, 1800r/ Min or 2000r/min.

By selecting specific mixing speed, mixing time, homogeneous speed and homogenizing time, each component can effectively ensure that Be sufficiently mixed uniformly, avoid influence cosmetics using effect, property stable homogeneous is finally prepared and have both antipollution and The cosmetics of anti-inflammatory effect.

In order to further appreciate that the present invention, combined with specific embodiments below with comparative example to product of the present invention method and effect It elaborates.Each raw material component of the present invention can be obtained by purchase.

Embodiment 1

A kind of skin matrix is mainly grouped as by following group by mass percentage: 1,2- pentanediol 4%, butanediol 10%, wing seed Moringa seed extract 5%, Ganodenna Lucidum P.E 5%, licorice root extract 5%, Flos Nelumbinis extract 5%, water 66%.

The preparation method of skin matrix, includes the following steps:

(1) it is heated to 85 DEG C after mixing water, 1,2- pentanediol and butanediol, keeps the temperature 30min, obtains clear solution.

(2) clear solution is cooled to 38 DEG C, wing seed Moringa seed extract, Ganodenna Lucidum P.E, licorice root extract is added And Flos Nelumbinis extract, 10min, mixing speed 1000r/min are stirred, is discharged with 200 mesh filter-cloth filterings, obtains skin matrix.

Embodiment 2

A kind of skin matrix is mainly grouped as by following group by mass percentage: 1,2- pentanediol 4%, butanediol 10%, wing seed Moringa seed extract 3%, Ganodenna Lucidum P.E 3%, licorice root extract 3%, Flos Nelumbinis extract 3%, water 74%.

The preparation method of skin matrix, includes the following steps:

(1) it is heated to 90 DEG C after mixing water, 1,2- pentanediol and butanediol, keeps the temperature 20min, obtains clear solution；

(2) clear solution is cooled to 40 DEG C, be added seed Moringa seed extract, Ganodenna Lucidum P.E, licorice root extract and Flos Nelumbinis extract stirs 5min, mixing speed 800r/min, is discharged with 300 mesh filter-cloth filterings, obtains skin matrix.

Embodiment 3

A kind of skin matrix is mainly grouped as by following group by mass percentage: 1,2- pentanediol 4%, butanediol 10%, wing seed Moringa seed extract 10%, Ganodenna Lucidum P.E 8%, licorice root extract 8%, Flos Nelumbinis extract 8%, water 52%.

The preparation method of skin matrix, includes the following steps:

(1) it is heated to 87 DEG C after mixing water, 1,2- pentanediol and butanediol, keeps the temperature 25min, obtains clear solution；

(2) seed Moringa seed extract, Ganodenna Lucidum P.E, licorice is added thereto after clear solution is cooled to 35 DEG C to mention Object and lotus flower root extract are taken, 8min, mixing speed 900r/min are stirred, is discharged with 250 mesh filter-cloth filterings, obtains skin care base Matter.

Embodiment 4

A kind of skin matrix is mainly grouped as by following group by mass percentage: 1,2- pentanediol 5%, butanediol 12%, wing seed Moringa seed extract 8%, Ganodenna Lucidum P.E 1%, licorice root extract 1%, lotus flower root extract 10%, water 63%.

The preparation method of skin matrix, with embodiment 1.

Embodiment 5

A kind of skin matrix is mainly grouped as by following group by mass percentage: 1,2- pentanediol 3%, butanediol 15%, wing seed Moringa seed extract 1%, Ganodenna Lucidum P.E 10%, licorice root extract 10%, Flos Nelumbinis extract 1%, water 60%.

The preparation method of skin matrix, with embodiment 1.

Embodiment 6

A kind of skin care cream is mainly grouped as by following group by mass percentage:

Component A: isooctadecanol/butanediol cocounut oil acid esters/ethyl cellulose 5%, isononyl isononanoate 2.5%, Australia are hard Fruit seed oil 2.5%, dimethyl silicone polymer 2.5%.

B component: glycerol 8%, butanediol 4%, acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymer 0.3%, surplus is water.

Component C: triethanolamine 0.12%.

D component: sodium acrylate/sodium acryloyldimethyl taurate copolymers/isohexadecane/Polyoxyethylene Sorbitan Monooleate/water/ The smooth oleate 0.8% of sorb.

Component E: skin matrix prepared by essence 0.02%, 30% embodiment 1.

The preparation method of skin care cream, includes the following steps:

(1) component A is sequentially added into oily phase pot, 1000r/min is stirred and is warming up to 85 DEG C, and heat preservation 10min obtains oily phase Ingredient；

(2) water phase pot is added in B component, 1000r/min stir and is warming up to 85 DEG C, heat preservation 20min, obtain water phase at Point；

(3) after water-phase component being sucked emulsion pot, emulsion pot stirring, mixing speed 600r/min are opened, then slowly will Oil-phase component sucks emulsion pot, and then holding -0.05MPa vacuum and mixing speed are constant, opens outer circulation homogenizer immediately Homogeneous, homogenizing time 5min are carried out, homogeneous speed is 3000r/min；

(4) component C is added after the completion of homogeneous, and opens outer circulation homogenizer and carries out homogeneous, homogenizing time 3min, Matter speed is 2000r/min；

(5) D component is added after the completion of homogeneous, and opens outer circulation homogenizer and carries out homogeneous, homogenizing time 3min, Matter speed is 2000r/min；

(6) temperature lowering water being opened after the completion of homogeneous and being cooled to 45 DEG C, component E is added and stirs 5min, mixing speed 600r/ Min is then turned on interior circulation homogenizer homogeneous 1min, and homogeneous speed is 2000r/min, obtains skin care cream.

Embodiment 7

Component A: isooctadecanol/butanediol cocounut oil acid esters/ethyl cellulose 3%, isononyl isononanoate 1%, Queensland nut Seed oil 1%, dimethyl silicone polymer 5%.

B component: glycerol 4%, butanediol 10%, acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymer 0.5%, surplus is water.

Component C: triethanolamine 0.15%.

D component: sodium acrylate/sodium acryloyldimethyl taurate copolymers/isohexadecane/Polyoxyethylene Sorbitan Monooleate/water/ The smooth oleate 1.2% of sorb.

Component E: the skin matrix of 20% embodiment 2 preparation, essence 0.03%.

The preparation method of skin care cream, includes the following steps:

(1) component A is sequentially added into oily phase pot, 900r/min is stirred and is warming up to 90 DEG C, and heat preservation 5min obtains oil and coordinates Point；

(2) water phase pot is added in B component, 900r/min is stirred and is warming up to 90 DEG C, and heat preservation 10min obtains water-phase component；

(3) after water-phase component being sucked emulsion pot, emulsion pot stirring, mixing speed 800r/min are opened, then slowly will Oil-phase component sucks emulsion pot, and then holding -0.08MPa vacuum and mixing speed are constant, opens outer circulation homogenizer immediately Homogeneous, homogenizing time 3min are carried out, homogeneous speed is 2000r/min；

(4) component C is added after the completion of homogeneous, and opens outer circulation homogenizer and carries out homogeneous, homogenizing time 3min, Matter speed is 1000r/min；

(5) D component is added after the completion of homogeneous, and opens outer circulation homogenizer and carries out homogeneous, homogenizing time 3min, Matter speed is 1000r/min；

(6) temperature lowering water being opened after the completion of homogeneous and being cooled to 40 DEG C, component E is added and stirs 3min, mixing speed 800r/ Min is then turned on interior circulation homogenizer homogeneous 3min, and homogeneous speed is 1000r/min, obtains skin care cream.

Embodiment 8

Component A: isooctadecanol/butanediol cocounut oil acid esters/ethyl cellulose 7%, isononyl isononanoate 5%, Queensland nut Seed oil 5%, dimethyl silicone polymer 1%.

B component: glycerol 10%, butanediol 8%, acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymer 0.1%, surplus is water.

Component C: triethanolamine 0.08%.

D component: sodium acrylate/sodium acryloyldimethyl taurate copolymers/isohexadecane/Polyoxyethylene Sorbitan Monooleate/water/ The smooth oleate 0.5% of sorb.

Component E: the skin matrix of 25% embodiment 3 preparation, essence 0.01%.

The preparation method of skin care cream, includes the following steps:

(1) component A is sequentially added into oily phase pot, 800r/min is stirred and is warming up to 87 DEG C, and heat preservation 8min obtains oil and coordinates Point；

(2) water phase pot is added in B component, 800r/min is stirred and is warming up to 90 DEG C, and heat preservation 15min obtains water-phase component；

(3) after water-phase component being sucked emulsion pot, emulsion pot stirring, mixing speed 700r/min are opened, then slowly will Oil-phase component sucks emulsion pot, and then holding -0.08MPa vacuum and mixing speed are constant, opens outer circulation homogenizer immediately Homogeneous, homogenizing time 4min are carried out, homogeneous speed is 2500r/min；

(4) component C is added after the completion of homogeneous, and opens outer circulation homogenizer and carries out homogeneous, homogenizing time 4min, Matter speed is 1500r/min；

(5) D component is added after the completion of homogeneous, and opens outer circulation homogenizer and carries out homogeneous, homogenizing time 4min, Matter speed is 1500r/min；

(6) temperature lowering water being opened after the completion of homogeneous and being cooled to 42 DEG C, component E is added and stirs 4min, mixing speed 700r/ Min is then turned on interior circulation homogenizer homogeneous 2min, and homogeneous speed is 1500r/min, obtains skin care cream.

Embodiment 9

A kind of skin care cream, according to mass percentage, except the skin matrix in component E is made from 30% embodiment 4 Outside skin matrix, other components and content are the same as embodiment 6.

The preparation method of skin care cream is the same as embodiment 6.

Embodiment 10

A kind of skin care cream, according to mass percentage, except the skin matrix in component E is made from 30% embodiment 5 Outside skin matrix, other components and content are the same as embodiment 6.

The preparation method of skin care cream is the same as embodiment 6.

Comparative example 1

A kind of skin matrix, according to mass percentage, in addition to without wing seed Moringa seed extract, other components and content It with embodiment 1, and is adaptively adjusted, i.e., supplies the content of wing seed Moringa seed extract with water.

The preparation method is the same as that of Example 1 for skin matrix.

Comparative example 2

A kind of skin matrix, according to mass percentage, in addition to without Ganodenna Lucidum P.E, other components and content are the same as real Example 1 is applied, and is adaptively adjusted, i.e., supplies the content of Ganodenna Lucidum P.E with water.

The preparation method is the same as that of Example 1 for skin matrix.

Comparative example 3

A kind of skin matrix, according to mass percentage, in addition to without licorice root extract, other components and content are same Embodiment 1, and be adaptively adjusted, i.e., the content of licorice root extract is supplied with water.

The preparation method is the same as that of Example 1 for skin matrix.

Comparative example 4

A kind of skin matrix, according to mass percentage, in addition to without Flos Nelumbinis extract, other components and content are the same as real Example 1 is applied, and is adaptively adjusted, i.e., supplies the content of Flos Nelumbinis extract with water.

The preparation method is the same as that of Example 1 for skin matrix.

Comparative example 5

A kind of skin care cream, according to mass percentage, except the skin matrix in component E is made from 30% comparative example 1 Outside skin matrix, other components and content are the same as embodiment 6.

The preparation method of skin care cream, with embodiment 6.

Comparative example 6

A kind of skin care cream, according to mass percentage, except the skin matrix in component E is made from 30% comparative example 2 Outside skin matrix, other components and content are the same as embodiment 6.

The preparation method of skin care cream, with embodiment 6.

Comparative example 7

A kind of skin care cream, according to mass percentage, except the skin matrix in component E is made from 30% comparative example 3 Outside skin matrix, other components and content are the same as embodiment 6.

The preparation method of skin care cream, with embodiment 6.

Comparative example 8

A kind of skin care cream, according to mass percentage, except the skin matrix in component E is made from 30% comparative example 4 Outside skin matrix, other components and content are the same as embodiment 6.

The preparation method of skin care cream, with embodiment 6.

Effect example

1, the attachment of dust in air particle is tested

(1) it (is made of I-type collagen and human body cell, the limited public affairs of Guangdong Bo Xi biotechnology using 3D artificial skin Department) it is tested, it is 2cm in every piece of area³The sample to be tested for spreading identical weight (0.3g) is uniformly applied on 3D artificial skin, Sample to be tested is the skin care cream of embodiment 6 and comparative example 5-8, and control group 1 (is prepared by embodiment 6, is free of skin matrix, water The amount of supplying), control group 2 (by the cream that embodiment 6 is prepared, the difference of skin matrix is with the difference of embodiment 6, this The formula of skin matrix used in control group is as follows: 1,2- pentanediol 4%, butanediol 10%, wing seed Moringa seed extract 20%, Water 66%), control group 3 (by the cream that embodiment 6 is prepared, the difference of skin matrix is with the difference of embodiment 6, this The formula of skin matrix used in control group is as follows: 1,2- pentanediol 4%, butanediol 10%, Ganodenna Lucidum P.E 20%, water 66%), control group 4 (by the cream that embodiment 6 is prepared, the difference of skin matrix is with the difference of embodiment 6, this is right It is as follows according to the formula of group skin matrix used: 1,2- pentanediol 4%, butanediol 10%, licorice root extract 20%, water 66%), control group 5 (by the cream that embodiment 6 is prepared, the difference of skin matrix is with the difference of embodiment 6, this is right It is as follows according to the formula of group skin matrix used: 1,2- pentanediol 4%, butanediol 10%, Flos Nelumbinis extract 20%, water 66%)； Control group 6 (by the cream that embodiment 6 is prepared, the difference of skin matrix is with the difference of embodiment 6, this control group institute The formula of skin matrix is as follows: 1,2- pentanediol 4%, butanediol 10%, wing seed Moringa seed extract 5%, ganoderma lucidum are extracted Object 5%, Honegsukle flower P.E 5%, Flos Nelumbinis extract 5%, water 66%)；It is parallel that each test group is arranged 3, while sky is arranged White control group (not smearing anything on 3D artificial skin).

(2) show that air quality index is the date of slight pollution in weather forecast, with triumphant Sheng sun SDL301 laser PM2.5 It is 108 μ g/m that detector, which measures PM2.5 in the busy section of wagon flow,³When take air.By the device of the air equipped with slight pollution It is connect with detection case.It will test case and be evacuated to -0.1MPa, continue to take out 5min vacuum, open the air that slight pollution is housed Device and detection case between valve, the air of slight pollution is injected into detection case, the pressure in measuring tank to be checked is 1 big When air pressure, the 3D artificial skin that step (1) painting wipes sample to be tested is put into detection case, 8 hours are placed.

(3) then sample is taken out, is weighed, before weight-detection after weight=detection of adhering contaminant Weight.

Experimental result is as shown in table 1:

Attachment experimental result of the table 1 to dust in air particle

Embodiment 6	Comparative example 5	Comparative example 6	Comparative example 7	Comparative example 8	Blank control group
						The weight (g) of adhering contaminant	0.0034	0.0046	0.0040	0.0041	0.0040	0.0049
Control group 1	Control group 2	Control group 3	Control group 4	Control group 5	Control group 6
						The weight (g) of adhering contaminant	0.0048	0.0038	0.0046	0.0045	0.0047	0.0039

2, the tolerance of stimulant is tested

Experimental method: 100 female volunteers (age is 30-40 years old, average age 35 years old) is selected, stochastic averagina is divided into 10 groups, after daily face cleaning, on the cheek of each volunteer, left cheek coats the cream type cosmetics of embodiment 6, right face respectively The corresponding cream type cosmetics for smearing comparative example 5-8 of cheek, the cream type cosmetics of control group 1~6 (being prepared by step (1))；Often The amount that group uses every time is all the same, and laggard assassinate swashs test within continuous use 3 weeks.

The step of stimulation test, is as follows: after taking percent by volume to be applied to nose two sides for 10% 50 μ L of lactic acid solution, Carry out reply reaction assessment.Evaluation criteria is as follows: 0 point is no tingling sensation, and 1 point is slight shouting pain, and 2 points are moderate shouting pain, and 3 points are It is as shown in table 2 to there is fever, erythema or redness, test result.

Tolerance test result of the table 2 to stimulant

	Left face stimulation scoring	Right face stimulation scoring	Difference
				Embodiment 6, comparative example 5	1.2	2.3	1.1
Embodiment 6, comparative example 6	1.3	2.6	1.3
				Embodiment 6, comparative example 7	1.2	2.8	1.6
Embodiment 6, comparative example 8	1.1	2.5	1.4
				Embodiment 6, control group 1	1.2	3.0	1.8
Embodiment 6, control group 2	1.3	2.6	1.3
				Embodiment 6, control group 3	1.1	2.0	0.9
Embodiment 6, control group 4	1.1	1.8	0.7
				Embodiment 6, control group 5	1.2	2.3	1.1
Embodiment 6, control group 6	1.1	1.6	0.5

Relative to common cream it can be seen from the test result of table 2, the skin of antipollution cosmetics of the invention is smeared Skin, uncomfortable degree reduces after stimulated, this illustrates that the present invention has effects that anti-inflammatory, enhancing to the tolerance of stimulant.

The above embodiment is a preferred embodiment of the present invention, but embodiments of the present invention are not by above-described embodiment Limitation, other any changes, modifications, substitutions, combinations, simplifications made without departing from the spirit and principles of the present invention, It should be equivalent substitute mode, be included within the scope of the present invention.

Claims

1. a kind of skin matrix with antipollution and anti-inflammatory efficacy, it is characterised in that mainly comprising it is following as mass fraction Component: 1,2- pentanediol 3~5%, butanediol 10~15%, wing seed Moringa seed extract 1~10%, Ganodenna Lucidum P.E 1~ 10%, licorice root extract 1~10%, Flos Nelumbinis extract 1~10%.

2. the skin matrix according to claim 1 with antipollution and anti-inflammatory efficacy, it is characterised in that it is main comprising with Under component as mass fraction: 1,2- pentanediol 4~5%, butanediol 12~14%, wing seed Moringa seed extract 3~7%, Ganodenna Lucidum P.E 3~7%, licorice root extract 3~7%, Flos Nelumbinis extract 3~7%.

3. the skin matrix according to claim 1 or 2 with antipollution and anti-inflammatory efficacy, it is characterised in that: also include Water；Or also comprising at least one of other function skin care substance, preservative, pigment and essence ingredient and water.

4. the preparation method of the described in any item skin matrixes with antipollution and anti-inflammatory efficacy of claims 1 to 3, feature Be the following steps are included:

(2) clear solution for obtaining step (1) cools down, and wing seed Moringa seed extract, Ganodenna Lucidum P.E, licorice is added and extracts Object and Flos Nelumbinis extract are uniformly mixed, obtain the skin matrix with antipollution and anti-inflammatory efficacy.

5. the preparation method of the skin matrix according to claim 4 with antipollution and anti-inflammatory efficacy, it is characterised in that:

The temperature of heating described in step (1) is 85~90 DEG C；

The time of heat preservation described in step (1) is 20~30min；

It is mixed into described in step (1) by the way of stirring；

The temperature of cooling described in step (2) is 35~40 DEG C；

Uniformly mixed mode described in step (2) is stirring；

It further include separating step after the uniformly mixed step in step (2).

6. the skin matrix of any of claims 1 or 2 with antipollution and anti-inflammatory efficacy is preparing the application in cosmetics.

7. a kind of cosmetics with antipollution and anti-inflammatory efficacy, it is characterised in that: have comprising of any of claims 1 or 2 The skin matrix of antipollution and anti-inflammatory efficacy.

8. the cosmetics according to claim 7 with antipollution and anti-inflammatory efficacy, it is characterised in that: the skin care base Content of the matter in the cosmetics is mass percent 20~30%.

9. the cosmetics according to claim 7 or 8 with antipollution and anti-inflammatory efficacy, it is characterised in that: comprising following Component by mass percentage:

Component A: isooctadecanol/butanediol cocounut oil acid esters/ethyl cellulose 3~7%, isononyl isononanoate 1~5%, Australia are hard Fruit seed oil 1~5%, dimethyl silicone polymer 1~5%；

B component: glycerol 4~10%, butanediol 4~10%, acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymer 0.1~0.5%, surplus is water；

Component C: triethanolamine 0.08~0.15%；

D component: sodium acrylate/sodium acryloyldimethyl taurate copolymers/isohexadecane/Polyoxyethylene Sorbitan Monooleate/water/sorb Smooth oleate 0.5~1.2%；

Component E: skin matrix 20~30% of any of claims 1 or 2, essence 0~appropriate.

10. the preparation method of the cosmetics as claimed in claim 9 with antipollution and anti-inflammatory efficacy, it is characterised in that including such as Lower step:

3) water phase is sucked into emulsion pot, mutually sucks emulsion pot for oily again after mixing evenly, keeps vacuum and mixing speed constant, Matter；