CN109851547B - 一种醋酸巴多昔芬晶型d的制备方法及用途 - Google Patents
一种醋酸巴多昔芬晶型d的制备方法及用途 Download PDFInfo
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CN111060619B (zh) * | 2019-12-18 | 2022-11-18 | 北京鑫开元医药科技有限公司 | 一种醋酸巴多昔芬杂质的检测方法 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2010151541A1 (en) * | 2009-06-23 | 2010-12-29 | Wyeth Llc | Polymorphic form d of bazedoxifene acetate and methods of preparing same |
CN102395561A (zh) * | 2009-04-13 | 2012-03-28 | 桑多斯股份公司 | 合成巴多昔芬乙酸酯及其中间体的方法 |
CN103864664A (zh) * | 2012-12-18 | 2014-06-18 | 江苏柯菲平医药有限公司 | 巴多昔芬乙酸盐新晶型及其制备方法 |
CN105669518A (zh) * | 2014-12-04 | 2016-06-15 | 上海医药集团股份有限公司 | 醋酸巴多昔芬及其a晶型的制备方法 |
KR20170029141A (ko) * | 2015-09-07 | 2017-03-15 | 주식회사 경보제약 | 고순도 바제독시펜 아세테이트의 제조방법 |
CN107793344A (zh) * | 2017-10-24 | 2018-03-13 | 扬子江药业集团有限公司 | 一种醋酸巴多昔芬的工业化生产方法 |
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Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
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CN102395561A (zh) * | 2009-04-13 | 2012-03-28 | 桑多斯股份公司 | 合成巴多昔芬乙酸酯及其中间体的方法 |
WO2010151541A1 (en) * | 2009-06-23 | 2010-12-29 | Wyeth Llc | Polymorphic form d of bazedoxifene acetate and methods of preparing same |
CN103864664A (zh) * | 2012-12-18 | 2014-06-18 | 江苏柯菲平医药有限公司 | 巴多昔芬乙酸盐新晶型及其制备方法 |
CN105669518A (zh) * | 2014-12-04 | 2016-06-15 | 上海医药集团股份有限公司 | 醋酸巴多昔芬及其a晶型的制备方法 |
KR20170029141A (ko) * | 2015-09-07 | 2017-03-15 | 주식회사 경보제약 | 고순도 바제독시펜 아세테이트의 제조방법 |
CN107793344A (zh) * | 2017-10-24 | 2018-03-13 | 扬子江药业集团有限公司 | 一种醋酸巴多昔芬的工业化生产方法 |
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Inventor after: Wu Yanpeng Inventor after: Li Jing Inventor after: Pang Yalong Inventor after: Ge Zhimin Inventor after: Dai Xinmin Inventor before: Wu Yanpeng Inventor before: Li Jing Inventor before: Pang Yalong Inventor before: Ge Zhimin |
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Denomination of invention: A Preparation Method and Application of Batixifen Acetate Crystal Form D Effective date of registration: 20230829 Granted publication date: 20200908 Pledgee: Industrial Bank Co.,Ltd. Beijing Pinggu Branch Pledgor: BEIJING XINKAIYUAN PHARMACEUTICAL TECHNOLOGY CO.,LTD. Registration number: Y2023110000364 |