CN109730954A - It is quick with town, releive, maintenance, the skin care item and preparation method thereof for improving sebum film effect - Google Patents
It is quick with town, releive, maintenance, the skin care item and preparation method thereof for improving sebum film effect Download PDFInfo
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Abstract
That the invention discloses a kind of is quick with town, releive, maintenance, skin care item for improving sebum film effect and preparation method thereof, and ingredient includes Radix Cynanchi Atrati extract, trehalose, german chamomile flower extract, Radix Malvae sylvestris flower extract, Chinese herbaceous peony root extract, honeysuckle flower extract, Europe dandelion rhizome/root extract, Herba Violae extract, aloe barbadensis Miller leaf juice, double-docosyl alcohol/isooctadecanol/phytosterol dimerization Asia oleyl alcohol dimerized linoleic acid ester, oligopeptides -1, bisabolol, Cer NP, tocopherol (vitamin E).Skin care item of the invention serve many purposes, can town it is quick releive but also maintenance improve sebum barrier；Simultaneously because this is water solubility at subassembly, so not limited by product forms, aqua, lotion, cream, essence etc. can be made an addition to；Have the function of that town is quick, releive, maintenance, improving sebum film and effect；Thoroughly compensate for the obvious shortcoming that commercial product has a single function.
Description
Technical field
The present invention relates to a kind of skin care item more particularly to it is a kind of it is quick with town, releive, maintenance, improve sebum film effect
Skin care item and preparation method thereof.
Background technique
Environmental pollution, air deterioration are that developing country seeks rapid economic development and leads to negative results.To human body
One of barrier --- for skin, this is severe test together, works as environmental change, air pollution, ultraviolet radiation, life work
Cease irregular, under the multi-party pressure of job and life stress etc., skin condition can worse and worse, and problem becomes increasingly conspicuous, such as moisture stream
Mistake, sebum membrane equilibrium are destroyed, barrier is impaired, and collagen loss, flexibility missing, skin day occurs in melanin pigmentation, subsequent skin corium
Benefit seems dry, dim, sensitive, loose, general red, dry line, microgroove ... to extend the skin service life and resist years aging, skin
Skin is badly in need of being saved.However most of currently used cosmetics are indefinite there are effect and asking for certain adverse reaction occur
Topic, people are highly desirable to definite effect, effect by way of multiplicity, safely, have no adverse reaction with town is quick, releive, maintenance,
Improve the product of sebum film effect effect.
Summary of the invention
The purpose of the present invention is to solve the above problems, and provide a kind of definite effect, purposes multiplicity, safety, invariably
Good reaction has that town is quick, releive, maintenance, skin care item for improving sebum film effect and preparation method thereof.
To achieve the goals above, the present invention adopts the following technical scheme:
It is a kind of it is quick with town, releive, maintenance, the skin care item for improving sebum film effect, including following components: Radix Cynanchi Atrati extract
(CYNANCHUM ATRATUM), trehalose, german chamomile (CHAMOMILLA RECUTITA) flower extract, Ou Jin (MALVA
SYLVESTRIS) sunflower extract, Chinese herbaceous peony (PAEONIA ALBIFLORA) root extract, honeysuckle (LONICERA JAPONICA)
Flower extract, Europe dandelion (TARAXACUM OFFICINALE) rhizome/root extract, viola mandshurica (VIOLA
YEDOENSIS) extract, aloe barbadensis Miller (ALOE BARBADENSIS) leaf juice, double-docosyl alcohol/isooctadecanol/phytosterol
Dimerization Asia oleyl alcohol dimerized linoleic acid ester, oligopeptides -1, bisabolol, Cer NP, tocopherol (vitamin E).
Further, the component is by weight percentage are as follows: radix cynanchi atrati (CYNANCHUM ATRATUM) extract is 0.25%
~5%, trehalose be 0.25%~5%, german chamomile (CHAMOMILLA RECUTITA) flower extract be 0.002%~0.04%,
Radix Malvae sylvestris (MALVA SYLVESTRIS) flower extract is that 0.002%~0.04%, Chinese herbaceous peony (PAEONIA ALBIFLORA) root mentions
It is 0.002%~0.04%, Ou Pugong that take object, which be 0.002%~0.04%, honeysuckle (LONICERA JAPONICA) flower extract,
English (TARAXACUM OFFICINALE) rhizome/root extract is 0.002%~0.04%, viola mandshurica (VIOLA
YEDOENSIS it is 0.0001% that) extract, which is 0.002%~0.04%, aloe barbadensis Miller (ALOE BARBADENSIS) leaf juice,
~0.002%, double-docosyl alcohol/isooctadecanol/phytosterol dimerization Asia oleyl alcohol dimerized linoleic acid ester is 0.1%~2%, oligopeptides-
1 is 0.005%~0.1%, bisabolol is 0.1%~2%, Cer NP is 0.05%~1%, tocopherol (vitamin E)
It is 0.05%~1%.
Preferably, the component is by weight percentage are as follows: radix cynanchi atrati (CYNANCHUM ATRATUM) extract is 5%, seaweed
Sugar is that 5%, german chamomile (CHAMOMILLA RECUTITA) flower extract is 0.04%, Radix Malvae sylvestris (MALVA SYLVESTRIS) flower
Extract is that 0.04%, Chinese herbaceous peony (PAEONIA ALBIFLORA) root extract is 0.04%, honeysuckle (LONICERA
JAPONICA) flower extract is that 0.04%, Europe dandelion (TARAXACUM OFFICINALE) rhizome/root extract is
0.04%, viola mandshurica (VIOLA YEDOENSIS) extract is 0.04%, aloe barbadensis Miller (ALOE BARBADENSIS) leaf
Juice is 0.002%, double-docosyl alcohol/isooctadecanol/phytosterol dimerization Asia oleyl alcohol dimerized linoleic acid ester is 2%, oligopeptides -1 is
0.1%, bisabolol 2%, Cer NP 1%, tocopherol (vitamin E) are 1%.
Preferably, the component is by weight percentage are as follows: radix cynanchi atrati (CYNANCHUM ATRATUM) extract is 2.5%, sea
Algae sugar is that 2.5%, german chamomile (CHAMOMILLA RECUTITA) flower extract is 0.02%, Radix Malvae sylvestris (MALVA
SYLVESTRIS it is 0.02%, honeysuckle that) flower extract, which is 0.02%, Chinese herbaceous peony (PAEONIA ALBIFLORA) root extract,
(LONICERA JAPONICA) flower extract is that 0.02%, Europe dandelion (TARAXACUM OFFICINALE) rhizome/root extracts
Object is that 0.02%, viola mandshurica (VIOLA YEDOENSIS) extract is 0.02%, aloe barbadensis Miller (ALOE
BARBADENSIS) leaf juice is 0.001%, double-docosyl alcohol/isooctadecanol/phytosterol dimerization Asia oleyl alcohol dimerized linoleic acid ester is
1%, oligopeptides -1 is 0.05%, bisabolol 1%, Cer NP 0.5%, tocopherol (vitamin E) are 0.5%.
Preferably, the component is by weight percentage are as follows: radix cynanchi atrati (CYNANCHUM ATRATUM) extract is 0.25%,
Trehalose is that 0.25%, german chamomile (CHAMOMILLA RECUTITA) flower extract is 0.002%, Radix Malvae sylvestris (MALVA
SYLVESTRIS it is 0.002%, honeysuckle that) flower extract, which is 0.002%, Chinese herbaceous peony (PAEONIA ALBIFLORA) root extract,
(LONICERA JAPONICA) flower extract is that 0.002%, Europe dandelion (TARAXACUM OFFICINALE) rhizome/root mentions
It is 0.002%, aloe barbadensis Miller (ALOE that take object, which be 0.002%, viola mandshurica (VIOLA YEDOENSIS) extract,
BARBADENSIS) leaf juice is 0.0001%, double-docosyl alcohol/isooctadecanol/phytosterol dimerization Asia oleyl alcohol dimerized linoleic acid ester
It is 0.005% for 0.1%, oligopeptides -1, bisabolol 0.1%, Cer NP 0.05%, tocopherol (vitamin E) are
0.05%.
It is a kind of it is quick with town, releive, maintenance, improve sebum film effect skin care item preparation method, include the following steps:
(1) various raw materials in precise formula are held spare with vessel that are clean and disinfecting；
(2) by isononyl isononanoate, Nexbase 2004, cetylstearyl alcohol, dimethyl silicone polymer, cetearyl alcohol
Alcohol, cocoyl glucoside, Jojoba (SIMMONDSIA CHINENSIS) seed oil, stearine, PEG-100 stearate
Oily phase pot is added, warming while stirring is uniformly mixed it to 80 DEG C~85 DEG C, keeps the temperature 10~15 minutes；
(3) water phase pot, side stirring is added in water, glycerol, carbomer, parahydroxyacet-ophenone, Sodium Hyaluronate, EDETATE SODIUM
While being warming up to 80 DEG C~85 DEG C, makes it dissolve sufficiently, keep the temperature 10~15 minutes；
(4) preheating emulsion pot to 75~85 DEG C, first by water, glycerol, carbomer, parahydroxyacet-ophenone, Sodium Hyaluronate,
EDETATE SODIUM is pumped into, then by isononyl isononanoate, Nexbase 2004, cetylstearyl alcohol, dimethyl silicone polymer, whale
Wax stearyl alcohol, cocoyl glucoside, Jojoba (SIMMONDSIA CHINENSIS) seed oil, stearine, PEG-100 are hard
Resin acid ester is slowly pumped into, and emulsifying 15~30 minutes, keeps the temperature 20 minutes；
(5) 39~45 DEG C are cooled to, radix cynanchi atrati (CYNANCHUM ATRATUM) extract, trehalose, water, glycerol, mother is added
Chrysanthemum (CHAMOMILLA RECUTITA) flower extract, Radix Malvae sylvestris (MALVA SYLVESTRIS) flower extract, Chinese herbaceous peony (PAEONIA
ALBIFLORA) root extract, honeysuckle (LONICERA JAPONICA) flower extract, Europe dandelion (TARAXACUM
OFFICINALE) rhizome/root extract, viola mandshurica (VIOLA YEDOENSIS) extract, aloe barbadensis Miller (ALOE
BARBADENSIS) leaf juice, Phenoxyethanol, Sensiva SC50, double-docosyl alcohol/isooctadecanol/phytosterol dimerization Asia oleyl alcohol
Dimerized linoleic acid ester, glycerol, water, oligopeptides -1, bisabolol, Cer NP, tocopherol (vitamin E), polyacrylamide,
C13-14 isoparaffin, laureth -7, triethanolamine, glycerol caprylate, decoyl hydroximic acid, propylene glycol, Phenoxyethanol, and
It is sufficiently stirred；
(6) 30~38 DEG C are cooled to, is discharged, is stood；
(7) after the assay was approved, filling, packaging, coding, storage are stand-by.
Radix Cynanchi Atrati extract in the present invention is extracted from the radix cynanchi atrati of naturally occurring, and tradition application is upper, and radix cynanchi atrati can drop
Fire, thus can be in typhoid fever later period or postpartum consumption energy and blood of human body and body fluid and internal low fever does not weaken and cures physical fatigue
Fever after symptom, diuresis, useless fellow, malignant sore, sphagitis, is used the cough due to caused by waste heat on wound that snake stings.In skin care
On, in the research that the growth with inflammatory reaction correlation factor hinders effect, radix cynanchi atrati (CYNANCHUM ATRATUM) extract pair
The growth of IL-1 (Interleukin-1) has apparent inhibitory effect, i.e. radix cynanchi atrati (CYNANCHUM ATRATUM) extract has
There are good antiphlogistic effects.The manufacturer of Radix Cynanchi Atrati extract is RADIANT.
Trehalose is a kind of natural carbohydrate, belongs to small molecule moisturizer, has good compatibility with memebrane protein, can be used as skin
Skin bleeding agent increases absorption of the skin to nutritional ingredient.The aquation function of increasing cell, there is good moisture retention.
German chamomile (CHAMOMILLA RECUTITA) flower extract can be releived with moisturizing, toxin expelling, and help to repair skin
Barrier, and help to maintain the integrality of skin barrier.Radix Malvae sylvestris (MALVA SYLVESTRIS) flower extract can be to skin
There is good moisturizing to act on, the lost moisture content of supplement skin alleviates the allergic condition generated by skin water shortage.Chinese herbaceous peony
(PAEONIA ALBIFLORA) root extract can except antalgic and sedative act on it is outer, moreover it is possible to effectively for sensitivity skin cuticula compared with
The problem of thin and resilience declines, effective bacteriostasis antibiosis prevents skin inflammatory condition susceptible " revivable ".Honeysuckle
(LONICERA JAPONICA) flower extract can inhibit skin pigment to be formed and activate epidermal cell, and honeysuckle flowers contain spiceleaf
Alcohol can contain phenolic acid class with antibacterial, activation, healing, honeysuckle flowers, can be with antibacterial, anti-oxidant, anti-inflammatory, prevention scytitis.
Europe dandelion (TARAXACUM OFFICINALE) rhizome/root extract can have sterilization well and antibacterial effect, knot
Its anti-inflammatory and inoxidizability is closed, can be used for preventing scytitis.Viola mandshurica (VIOLA YEDOENSIS) extract can resist
Bacterium, anti-oxidant, analgesia, anti-inflammatory, viola mandshurica contains phytosterol, can keep skin surface moisture content, promotes skin newly old
Metabolism inhibits scytitis, prevents skin aging, and viola mandshurica contains saponin(e, can be anti-oxidant, and anti-aging enhances skin
Elasticity.Ultraviolet light can be absorbed in aloe barbadensis Miller (ALOE BARBADENSIS) leaf juice, prevents caused by excessive ultraviolet light
Skin allergy symptom, while again there is calmness to releive effect, it releives to by improper cosmetics bring irritation allergic symptom
Effect.The manufacturer of Sinocalmant plant Shu Min essence is ID bio.
Double-docosyl alcohol/isooctadecanol/phytosterol dimerization Asia oleyl alcohol dimerized linoleic acid ester is as skin conditioning agent, to skin
Skin has very high permeability, can keep skin surface moisture content, promotes skin metabolism, inhibits scytitis, can anti-day
The effect of shining erythema, skin aging.It may additionally facilitate wound healing, make hypertrophy, enhancing capillary circulation.Skin can be moistened
Skin optimizes sebum, maintenance skin barrier, and skin moisture-keeping prevents the evaporation of skin surface moisture, has good skin moisture-keeping effect
Fruit.
Oligopeptides -1 (inhuman oligopeptides -1), OLIGOPEPTIDE-1 have put on record CFDA Listed in Bureau of Drugs Supervision, meet Chinese law
Rule.Oligopeptides -1 is found by Pickar and Pilgeram in nineteen sixty-eight, is a kind of small-molecular peptides being made of 3 amino acid, is
ECM protein, the amino acid sequence in I-type collagen, can be swashed by the albumen enzyme r e lease of wound location, these molecules of release
Living and adjusting skin repair process.Oligopeptides -1 have promote promoting epidermization, stimulation extracellular matrix (ECM), I-type collagen,
III collagen type generates, and repairs skin barrier, improves red capillary, anti-ageing tender skin, the function of bright color.To winkey company
The oligopeptides -1 of buying.
Bisabolol plays the role of anti-inflammatory antibacterial, and the ingredient stability is good and skin has good compatibility, reduces skin
Inflammation mitigates acne, prevents dark sore from generating, and improves the anti-irritant ability of skin, repairs the skin for having inflammation injury, anti-
It shines in product and improves spf value, there is apparent anti-inflammatory effect.
Cer NP can penetrate into skin quickly, help the update of skin natural containment, can promote nature aquation
Balance and cuticula in water combine, form a kind of reticular structure, lock moisture.There is good action to skin moisturizing maintenance,
It is skin-active ingredient important in cuticula, skin barrier can be enhanced, reconstituted cell forms effective barrier to prevent water loss
With the influence for reducing external environment.The especially needed more ceramides of stimulated skin, some researches show that wipe containing nerve
The product of amide component can be reduced red and swollen and percutaneous water loss, improve sebum equilibrium state, plays enhancing skin barrier and helps
Impaired skin is helped to alleviate the effect of drying regime.
Tocopherol (vitamin E) can effectively antagonize free radical, inhibit lipid peroxide to generate, eliminate chloasma；Inhibit junket
The activity of propylhomoserin enzyme, to reduce melanin production.The vitamin E of esterified form can also be eliminated by ultraviolet light, air pollution etc.
Excessive oxygen radical caused by extraneous factor plays the effects of delaying light aging, prevention sunburn and sunburn is inhibited to generate.
The present invention complies fully with the indices in " cosmetics safety technical specification " (2015 editions) of country's promulgation, the shield
Skin product do not contain any noxious material.
Beneficial effects of the present invention: by adding radix cynanchi atrati (CYNANCHUM ATRATUM) extract, seaweed in formula
Sugar, german chamomile (CHAMOMILLA RECUTITA) flower extract, Radix Malvae sylvestris (MALVA SYLVESTRIS) flower extract, Chinese herbaceous peony
(PAEONIA ALBIFLORA) root extract, honeysuckle (LONICERA JAPONICA) flower extract, Europe dandelion
(TARAXACUM OFFICINALE) rhizome/root extract, viola mandshurica (VIOLA YEDOENSIS) extract, Curacao reed
Luxuriant growth (ALOE BARBADENSIS) leaf juice, double-docosyl alcohol/isooctadecanol/phytosterol dimerization Asia oleyl alcohol dimerized linoleic acid ester, widow
Peptide -1, bisabolol, Cer NP, tocopherol (vitamin E) at subassembly, extend the function of product, can town it is quick relax
The slow maintenance of energy again improves sebum barrier conditions；Simultaneously because this is water solubility at subassembly, so do not limited by product forms,
Aqua, lotion, cream, essence etc. can be made an addition to；One skin care item of the invention can be used in multiple use, have town
It is quick, releive, maintenance, improve sebum film effect and effect.Thoroughly compensate for the obvious shortcoming that commercial product has a single function.
Specific embodiment
The present invention is illustrated below with reference to embodiment, but the present invention is not limited to these embodiments.
The present invention is achieved through the following technical solutions: a kind of with having, town is quick, releive, maintenance, improves sebum film work
Skin care item are prepared by following materials by weight percentage using conventional method:
1 composition of raw materials table of table
Wherein: radix cynanchi atrati (CYNANCHUM ATRATUM) extract: trehalose: Sinocalmant plant Shu Min essence: double-
Docosyl alcohol/isooctadecanol/phytosterol dimerization Asia oleyl alcohol dimerized linoleic acid ester: OLIGOPEPTIDE-1: bisabolol: neural acyl
Amine 3: tocopherol (vitamin E)=5:5:2:2:2:2:1:1.
Radix cynanchi atrati (CYNANCHUM ATRATUM) extract, trehalose, Sinocalmant plant Shu Min essence, double-behenyl
Alcohol/isooctadecanol/phytosterol dimerization Asia oleyl alcohol dimerized linoleic acid ester, OLIGOPEPTIDE-1, bisabolol, ceramide,
The percentage composition in (water, cream, frost) skin-protection product is added are as follows: 1~20% in tocopherol (vitamin E).
OLIGOPEPTIDE-1 is made of following components: glycerol, water, oligopeptides -1.
Sinocalmant plant Shu Min essence is made of following components: water, glycerol, german chamomile (CHAMOMILLA
RECUTITA) flower extract, Radix Malvae sylvestris (MALVA SYLVESTRIS) flower extract, Chinese herbaceous peony (PAEONIA ALBIFLORA) root
Extract, honeysuckle (LONICERA JAPONICA) flower extract, Europe dandelion (TARAXACUM OFFICINALE) rhizome/root
Extract, viola mandshurica (VIOLA YEDOENSIS) extract, aloe barbadensis Miller (ALOE BARBADENSIS) leaf juice, benzene oxygen
Ethyl alcohol, Sensiva SC50.
The specific preparation process of skin care item of the invention is as follows:
(8) various raw materials in precise formula are held with vessel that are clean and disinfecting；
(9) by isononyl isononanoate, Nexbase 2004, cetylstearyl alcohol, dimethyl silicone polymer, cetearyl alcohol
Alcohol, cocoyl glucoside, Jojoba (SIMMONDSIA CHINENSIS) seed oil, stearine, PEG-100 stearate
Oily phase pot is added, warming while stirring is uniformly mixed it to 80 DEG C~85 DEG C, keeps the temperature 10~15 minutes；
(10) water phase pot is added in water, glycerol, carbomer, parahydroxyacet-ophenone, Sodium Hyaluronate, EDETATE SODIUM, while stirring
It mixes side and is warming up to 80 DEG C~85 DEG C, make it dissolve sufficiently, keep the temperature 10~15 minutes；
(11) preheating emulsion pot to 75~85 DEG C, first by water, glycerol, carbomer, parahydroxyacet-ophenone, Sodium Hyaluronate,
EDETATE SODIUM is pumped into, then by isononyl isononanoate, Nexbase 2004, cetylstearyl alcohol, dimethyl silicone polymer, whale
Wax stearyl alcohol, cocoyl glucoside, Jojoba (SIMMONDSIA CHINENSIS) seed oil, stearine, PEG-100 are hard
Resin acid ester is slowly pumped into, and emulsifying 15~30 minutes, keeps the temperature 20 minutes；
(12) be cooled to 39~45 DEG C, be added radix cynanchi atrati (CYNANCHUM ATRATUM) extract, trehalose, water, glycerol,
German chamomile (CHAMOMILLA RECUTITA) flower extract, Radix Malvae sylvestris (MALVA SYLVESTRIS) flower extract, Chinese herbaceous peony
(PAEONIA ALBIFLORA) root extract, honeysuckle (LONICERA JAPONICA) flower extract, Europe dandelion
(TARAXACUM OFFICINALE) rhizome/root extract, viola mandshurica (VIOLA YEDOENSIS) extract, Curacao reed
Luxuriant growth (ALOE BARBADENSIS) leaf juice, Phenoxyethanol, Sensiva SC50, double-docosyl alcohol/isooctadecanol/phytosterol two
Poly- Asia oleyl alcohol dimerized linoleic acid ester, glycerol, water, oligopeptides -1, bisabolol, Cer NP, tocopherol (vitamin E), polypropylene
Amide, C13-14 isoparaffin, laureth -7, triethanolamine, glycerol caprylate, decoyl hydroximic acid, propylene glycol, benzene oxygen second
Alcohol, and be sufficiently stirred；
(13) 30~38 DEG C are cooled to, is discharged, is stood；
(14) after the assay was approved, filling, packaging, coding；
(15) after the assay was approved, it is put in storage.
Embodiment 1
Component in embodiment 1 is constituted by following weight percent: radix cynanchi atrati (CYNANCHUM ATRATUM) extract is
5%, trehalose 5%, german chamomile (CHAMOMILLA RECUTITA) flower extract are 0.04%, Radix Malvae sylvestris (MALVA
SYLVESTRIS it is 0.04%, honeysuckle that) flower extract, which is 0.04%, Chinese herbaceous peony (PAEONIA ALBIFLORA) root extract,
(LONICERA JAPONICA) flower extract is that 0.04%, Europe dandelion (TARAXACUM OFFICINALE) rhizome/root extracts
Object is that 0.04%, viola mandshurica (VIOLA YEDOENSIS) extract is 0.04%, aloe barbadensis Miller (ALOE
BARBADENSIS) leaf juice is 0.002%, double-docosyl alcohol/isooctadecanol/phytosterol dimerization Asia oleyl alcohol dimerized linoleic acid ester is
2%, oligopeptides -1 is 0.1%, bisabolol 2%, Cer NP 1%, tocopherol (vitamin E) are 1%.
Embodiment 2
Component in embodiment 2 is constituted by following weight percent: radix cynanchi atrati (CYNANCHUM ATRATUM) extract is
2.5%, trehalose 2.5%, german chamomile (CHAMOMILLA RECUTITA) flower extract are 0.02%, Radix Malvae sylvestris (MALVA
SYLVESTRIS it is 0.02%, honeysuckle that) flower extract, which is 0.02%, Chinese herbaceous peony (PAEONIA ALBIFLORA) root extract,
(LONICERA JAPONICA) flower extract is that 0.02%, Europe dandelion (TARAXACUM OFFICINALE) rhizome/root extracts
Object is that 0.02%, viola mandshurica (VIOLA YEDOENSIS) extract is 0.02%, aloe barbadensis Miller (ALOE
BARBADENSIS) leaf juice is 0.001%, double-docosyl alcohol/isooctadecanol/phytosterol dimerization Asia oleyl alcohol dimerized linoleic acid ester is
1%, oligopeptides -1 is 0.05%, bisabolol 1%, Cer NP 0.5%, tocopherol (vitamin E) are 0.5%.
Embodiment 3
Component in embodiment 3 is constituted by following weight percent: radix cynanchi atrati (CYNANCHUM ATRATUM) extract is
0.25%, trehalose 0.25%, german chamomile (CHAMOMILLA RECUTITA) flower extract are 0.002%, Radix Malvae sylvestris (MALVA
SYLVESTRIS it is 0.002%, honeysuckle that) flower extract, which is 0.002%, Chinese herbaceous peony (PAEONIA ALBIFLORA) root extract,
(LONICERA JAPONICA) flower extract is that 0.002%, Europe dandelion (TARAXACUM OFFICINALE) rhizome/root mentions
It is 0.002%, aloe barbadensis Miller (ALOE that take object, which be 0.002%, viola mandshurica (VIOLA YEDOENSIS) extract,
BARBADENSIS) leaf juice is 0.0001%, double-docosyl alcohol/isooctadecanol/phytosterol dimerization Asia oleyl alcohol dimerized linoleic acid ester
It is 0.005% for 0.1%, oligopeptides -1, bisabolol 0.1%, Cer NP 0.05%, tocopherol (vitamin E) are
0.05%.
Table 2: each component content table of Examples 1 to 3
Six, technical effect
Divide the effect of the skin care item and certain commercially available brand skin care item (reference examples) of implementing 1~3 to comparison of testing,
In, the skin care item of implementation 1~3 and the constituent content of certain commercially available brand skin care item are referring to table 1.
1, replenishing water and preserving moisture performance test
Female volunteers of 10 ages between 18~50 are looked for, in 20 DEG C, the indoor environment of relative humidity 50%, point
Draw one 2 square centimeters of fixed area in forehead, fixed area using the above moisturizing, maintenance, releive, anti-ageing skin care
It after product and commercially available common skin care item, is tested with Corneometer CM285 skin moisture detector, the comprehensive humidity of skin that obtains becomes
Change data, test result is as follows table:
Table 3: the replenishing water and preserving moisture performance control test table of embodiment 1-3
From the above experimental result as can be seen, make-up water percentage of the present invention and moisturizing rate, are relatively not added with radix cynanchi atrati (CYNANCHUM
ATRATUM) extract, trehalose, german chamomile (CHAMOMILLA RECUTITA) flower extract, Radix Malvae sylvestris (MALVA
SYLVESTRIS) flower extract, Chinese herbaceous peony (PAEONIA ALBIFLORA) root extract, honeysuckle (LONICERA JAPONICA) flower
Extract, Europe dandelion (TARAXACUM OFFICINALE) rhizome/root extract, viola mandshurica (VIOLA YEDOENSIS)
Extract, aloe barbadensis Miller (ALOE BARBADENSIS) leaf juice, double-docosyl alcohol/isooctadecanol/phytosterol dimerization Asia oleyl alcohol
Dimerized linoleic acid ester, oligopeptides -1, bisabolol, Cer NP, the reference examples of tocopherol (vitamin E) composition and commercially available
The moisturizing of common skin care item and moistening effect are significant.
2, skin smoothness change rate is tested
Look for female volunteers of 10 ages between 18~50 years old, respectively face using above have moisturizing, maintenance,
It releives, the skin care item of anti-ageing skin and commercially available common skin care item, study subject use once daily, continuous use 30 days, test
Period does not use other any products.Under the conditions of 25 ± 1 DEG C of environment temperature, humidity 50 ± 5%, using VISIA face-image
Analyzer test, comprehensive to obtain smoothness data, data value is higher, and expression skin smoothness is poorer.Test result is as follows table:
Table 4: the skin smoothness control test table of embodiment 1-3
| Sample | Before use | After use |
| Embodiment 1 | 2.9542 | 1.6241 |
| Embodiment 2 | 2.9243 | 1.6842 |
| Embodiment 3 | 2.9312 | 1.7243 |
| Reference examples | 2.8420 | 2.6112 |
| Commercially available common skin care item | 2.9311 | 2.4527 |
From the above experimental result as can be seen, skin smoothness of the present invention, is relatively not added with radix cynanchi atrati (CYNANCHUM
ATRATUM) extract, trehalose, german chamomile (CHAMOMILLA RECUTITA) flower extract, Radix Malvae sylvestris (MALVA
SYLVESTRIS) flower extract, Chinese herbaceous peony (PAEONIA ALBIFLORA) root extract, honeysuckle (LONICERA JAPONICA) flower
Extract, Europe dandelion (TARAXACUM OFFICINALE) rhizome/root extract, viola mandshurica (VIOLA YEDOENSIS)
Extract, aloe barbadensis Miller (ALOE BARBADENSIS) leaf juice, double-docosyl alcohol/isooctadecanol/phytosterol dimerization Asia oleyl alcohol
Dimerized linoleic acid ester, oligopeptides -1, bisabolol, Cer NP, the reference examples of tocopherol (vitamin E) composition and commercially available
The skin smoothness of common skin care item is good.
3, lactic acid shouting pain is tested
Pre-selection 25 are used as lactic acid sensitive subjects, at 20 DEG C, the interior of relative humidity 50% in tested volunteer (24 to 67 years old)
In environment, one 2 square centimeters of fixed area is drawn in forehead respectively, has that town is quick, releive, repair using above in fixed area
Shield, the skin care item and commercially available common skin care item for improving sebum film effect, study subject use once daily, are used continuously 7 days, survey
Other any products are not used during examination.In fixed area using above with town is quick, releive, maintenance, improves sebum film effect
Skin care item and commercially available common skin care item 1h and after 7 days again at fixed area apply 10% lactic acid solution, its itch of testing and assessing imitate
It answers.
In the case where dermatologist supervises, minute (no intensity) marks tingling sensation and continues 5 points subject from 0 to 3 per minute
Clock.If being better than 3 in the 3rd and the 5th minute mark value, then it is assumed that subject is shouting pain person.
Table 5: the lactic acid shouting pain control test table of Examples 1 to 3
| Sample | Before use | After 1h | After 7 days |
| Embodiment 1 | 6.0 | 3.5 | 3.0 |
| Embodiment 2 | 5.6 | 3.9 | 3.1 |
| Embodiment 3 | 5.8 | 4.2 | 3.3 |
| Reference examples | 5.3 | 5.1 | 4.9 |
| Commercially available common skin care item | 5.4 | 5.7 | 5.6 |
Most subjects feel quick town quick releive effect and feeling of pain, sense of discomfort, erythema, itch intensity and
The decrease of burning heat sensation.
From the above experimental result as can be seen, the quick effect of releiving in town of the present invention, is relatively not added with radix cynanchi atrati (CYNANCHUM
ATRATUM) extract, trehalose, german chamomile (CHAMOMILLA RECUTITA) flower extract, Radix Malvae sylvestris (MALVA
SYLVESTRIS) flower extract, Chinese herbaceous peony (PAEONIA ALBIFLORA) root extract, honeysuckle (LONICERA JAPONICA) flower
Extract, Europe dandelion (TARAXACUM OFFICINALE) rhizome/root extract, viola mandshurica (VIOLA YEDOENSIS)
Extract, aloe barbadensis Miller (ALOE BARBADENSIS) leaf juice, double-docosyl alcohol/isooctadecanol/phytosterol dimerization Asia oleyl alcohol
Dimerized linoleic acid ester, oligopeptides -1, bisabolol, Cer NP, the reference examples of tocopherol (vitamin E) composition and commercially available
The quick significant effect of releiving in town of common skin care item.
4, impaired skin is helped to restore test
Female volunteers of 15 ages between 18~50 are looked for, in 20 DEG C, the indoor environment of relative humidity 50%, point
The fixed area that one 2 square centimeters are drawn in forehead, in fixed area with the immersion of 5%SDS lotion 2 hours to destroy skin,
Then have that town is quick, releive, maintenance, the skin care item for improving sebum film effect and commercially available common skin care using above in fixed area
Product twice daily, continue fortnight, comprehensive to obtain skin hydration effect variation with the aquation of cutin measuring appliance measurement arm
Data (aquation value is higher to illustrate that the skin that is destroyed improves better by maintenance), test result is as follows table:
Table 6: the skin of Examples 1 to 3 restores control test table
| Sample | Before use | After 3 | After 7 days | After 14 days |
| Embodiment 1 | -12 | 17 | 18 | 19 |
| Embodiment 2 | -12 | 15 | 16 | 17 |
| Embodiment 3 | -11 | 12 | 13 | 14 |
| Reference examples | -10 | -4 | 1 | 1 |
| Commercially available common skin care item | -10 | -3 | 2 | 5 |
From the above experimental result as can be seen, skin repair improvement of the present invention, is relatively not added with radix cynanchi atrati (CYNANCHUM
ATRATUM) extract, trehalose, german chamomile (CHAMOMILLA RECUTITA) flower extract, Radix Malvae sylvestris (MALVA
SYLVESTRIS) flower extract, Chinese herbaceous peony (PAEONIA ALBIFLORA) root extract, honeysuckle (LONICERA JAPONICA) flower
Extract, Europe dandelion (TARAXACUM OFFICINALE) rhizome/root extract, viola mandshurica (VIOLA YEDOENSIS)
Extract, aloe barbadensis Miller (ALOE BARBADENSIS) leaf juice, double-docosyl alcohol/isooctadecanol/phytosterol dimerization Asia oleyl alcohol
Dimerized linoleic acid ester, oligopeptides -1, bisabolol, Cer NP, the reference examples of tocopherol (vitamin E) composition and commercially available
The skin repair improvement of common skin care item is significant.
5, skin repair efficacy test
Using EdU cell Proliferation detection method, by test specimen with town is quick, releive, maintenance, improves sebum film effect
Skin care item and commercially available common skin care item are added in culture medium, are incubated for people under certain condition and immortalize epidermal cell (HaCat), lead to
The EdU during penetrating into DNA replication dna in detection HaCat is crossed, can accurately detect newly to be proliferated by fluorescence detection tool thin
Born of the same parents, express statistic is in the percentage of cells of S phase, and then analyzes cell proliferative conditions.
Test result is as follows table:
Table 7: the skin repair efficacy test table of comparisons of embodiment 1-3
| Sample | Embodiment 1 | Embodiment 2 | Embodiment 3 | Reference examples | Commercially available common skin care item |
| Proliferation rate % | 60.75 | 55.43 | 50.34 | 1.32 | 3.13 |
From the above experimental result as can be seen, skin repair of the present invention, is relatively not added with radix cynanchi atrati (CYNANCHUM ATRATUM)
Extract, trehalose, german chamomile (CHAMOMILLA RECUTITA) flower extract, Radix Malvae sylvestris (MALVA SYLVESTRIS) flower mention
Take object, Chinese herbaceous peony (PAEONIA ALBIFLORA) root extract, honeysuckle (LONICERA JAPONICA) flower extract, Europe dandelion
(TARAXACUM OFFICINALE) rhizome/root extract, viola mandshurica (VIOLA YEDOENSIS) extract, Curacao reed
Luxuriant growth (ALOE BARBADENSIS) leaf juice, double-docosyl alcohol/isooctadecanol/phytosterol dimerization Asia oleyl alcohol dimerized linoleic acid ester, widow
Peptide -1, bisabolol, Cer NP, the reference examples of tocopherol (vitamin E) composition and commercially available common skin care item skin
It repairs significant.
The foregoing is merely better embodiments of the invention, and the invention is not limited to above embodiment, are implementing
The structural modification small there may be part in the process, if various changes or modifications of the invention are not departed from essence of the invention
Mind and range, and belong within the scope of claim and equivalent technologies of the invention, then the present invention is also intended to encompass these changes
And modification.
Claims (6)
1. it is a kind of it is quick with town, releive, maintenance, improve sebum film effect skin care item, which is characterized in that including following components:
Radix Cynanchi Atrati extract, trehalose, german chamomile flower extract, Radix Malvae sylvestris flower extract, Chinese herbaceous peony root extract, honeysuckle flower extract, Ou Pu
Radix Herba Taraxaci stem/root extract, Herba Violae extract, aloe barbadensis Miller leaf juice, double-docosyl alcohol/isooctadecanol/phytosterol two
Poly- Asia oleyl alcohol dimerized linoleic acid ester, oligopeptides -1, bisabolol, Cer NP, tocopherol.
Have that town is quick, releive, maintenance, the skin care item for improving sebum film effect 2. according to claim 1, feature exists
In the component is by weight percentage are as follows: Radix Cynanchi Atrati extract is 0.25%~5%, trehalose is 0.25%~5%, Flos Chrysanthemi
Extract is 0.002%~0.04%, Radix Malvae sylvestris flower extract is 0.002%~0.04%, Chinese herbaceous peony root extract is 0.002%
~0.04%, honeysuckle flower extract be 0.002%~0.04%, Europe dandelion rhizome/root extract be 0.002%~
0.04%, Herba Violae extract is 0.002%~0.04%, aloe barbadensis Miller leaf juice is 0.0001%~0.002%, it is double-
Docosyl alcohol/isooctadecanol/phytosterol dimerization Asia oleyl alcohol dimerized linoleic acid ester is 0.1%~2%, oligopeptides -1 be 0.005%~
0.1%, bisabolol is 0.1%~2%, Cer NP is 0.05%~1%, tocopherol is 0.05%~1%.
Have that town is quick, releive, maintenance, the skin care item for improving sebum film effect 3. according to claim 2, feature exists
In the component is by weight percentage are as follows: Radix Cynanchi Atrati extract 5%, trehalose 5%, german chamomile flower extract be 0.04%, Europe
High mallow flower extract is 0.04%, Chinese herbaceous peony root extract is 0.04%, honeysuckle flower extract is 0.04%, Europe dandelion rhizome/
Root extract is 0.04%, Herba Violae extract 0.04%, aloe barbadensis Miller leaf juice are 0.002%, double-docosyl alcohol/different
Stearyl alcohol/phytosterol dimerization Asia oleyl alcohol dimerized linoleic acid ester is 2%, oligopeptides -1 is 0.1%, bisabolol 2%, neural acyl
Amine 3 is 1%, tocopherol 1%.
Have that town is quick, releive, maintenance, the skin care item for improving sebum film effect 4. according to claim 2, feature exists
In the component is by weight percentage are as follows: Radix Cynanchi Atrati extract 2.5%, trehalose 2.5%, german chamomile flower extract are
0.02%, Radix Malvae sylvestris flower extract is 0.02%, Chinese herbaceous peony root extract is 0.02%, honeysuckle flower extract is 0.02%, Ou Pu
Radix Herba Taraxaci stem/root extract is 0.02%, Herba Violae extract 0.02%, aloe barbadensis Miller leaf juice are 0.001%, it is double-
Docosyl alcohol/isooctadecanol/phytosterol dimerization Asia oleyl alcohol dimerized linoleic acid ester is 1%, oligopeptides -1 is 0.05%, bisabolol is
1%, Cer NP 0.5%, tocopherol 0.5%.
Have that town is quick, releive, maintenance, the skin care item for improving sebum film effect 5. according to claim 2, feature exists
In the component is by weight percentage are as follows: Radix Cynanchi Atrati extract 0.25%, trehalose 0.25%, german chamomile flower extract are
0.002%, Radix Malvae sylvestris flower extract is 0.002%, Chinese herbaceous peony root extract is 0.002%, honeysuckle flower extract is 0.002%,
Europe dandelion rhizome/root extract is 0.002%, Herba Violae extract 0.002%, aloe barbadensis Miller leaf juice are
0.0001%, double-docosyl alcohol/isooctadecanol/phytosterol dimerization Asia oleyl alcohol dimerized linoleic acid ester is 0.1%, oligopeptides -1 is
0.005%, bisabolol 0.1%, Cer NP 0.05%, tocopherol 0.05%.
6. a kind of have that town is quick, releive, maintenance, the skin care item for improving sebum film effect for as claimed in claims 1-5
Preparation method, which comprises the steps of:
(1) various raw materials in precise formula are held spare with vessel that are clean and disinfecting；
(2) by isononyl isononanoate, Nexbase 2004, cetylstearyl alcohol, dimethyl silicone polymer, cetostearyl alcohol,
Oily phase pot is added in cocoyl glucoside, jojoba seed oil, stearine, PEG-100 stearate, and warming while stirring is arrived
80 DEG C~85 DEG C, it is uniformly mixed it, keeps the temperature 10~15 minutes；
(3) water phase pot is added in water, glycerol, carbomer, parahydroxyacet-ophenone, Sodium Hyaluronate, EDETATE SODIUM, risen while stirring
Temperature makes it dissolve sufficiently to 80 DEG C~85 DEG C, keeps the temperature 10~15 minutes；
(4) preheating emulsion pot is to 75~85 DEG C, first by water, glycerol, carbomer, parahydroxyacet-ophenone, Sodium Hyaluronate, EDTA bis-
Sodium is pumped into, then by isononyl isononanoate, Nexbase 2004, cetylstearyl alcohol, dimethyl silicone polymer, cetearyl alcohol
Alcohol, cocoyl glucoside, jojoba seed oil, stearine, PEG-100 stearate are slowly pumped into, and emulsifying 15~
30 minutes, keep the temperature 20 minutes；
(5) 39~45 DEG C are cooled to, Radix Cynanchi Atrati extract, trehalose, water, glycerol, german chamomile flower extract, Radix Malvae sylvestris flower is added and extracts
Object, Chinese herbaceous peony root extract, honeysuckle flower extract, Europe dandelion rhizome/root extract, Herba Violae extract, aloe barbadensis Miller
Leaf juice, Phenoxyethanol, Sensiva SC50, double-docosyl alcohol/isooctadecanol/phytosterol dimerization Asia oleyl alcohol dimerized linoleic acid ester,
Glycerol, water, oligopeptides -1, bisabolol, Cer NP, tocopherol, polyacrylamide, C13-14 isoparaffin, laruyl alcohol are poly-
Ether -7, triethanolamine, glycerol caprylate, decoyl hydroximic acid, propylene glycol, Phenoxyethanol, and be sufficiently stirred；
(6) 30~38 DEG C are cooled to, is discharged, is stood；
(7) after the assay was approved, filling, packaging, coding, storage are stand-by.
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Application publication date: 20190510 |