CN111419783A

CN111419783A - Revival grass skin-activating plant extract cream and preparation method thereof

Info

Publication number: CN111419783A
Application number: CN202010319338.9A
Authority: CN
Inventors: 张应贤
Original assignee: Guangzhou Lakel Stem Cell Research Institute
Current assignee: Guangzhou Lakel Stem Cell Research Institute
Priority date: 2020-04-21
Filing date: 2020-04-21
Publication date: 2020-07-17

Abstract

The invention discloses revived grass skin-activating plant extract cream and a preparation method thereof, and relates to the technical field of skin care products. The material comprises the following raw materials in percentage by mass: 0.01-0.05% of undaria pinnatifida extract, 0.1-0.5% of osmin plant allergy relieving essence, 0.01-0.03% of alteromonas ferment product extract, 0.1-0.5% of Ardisia mollissima leaf/stem extract, 0.1-0.2% of ascorbic acid (vitamin C), 16-30% of oil phase, 18.55-38.4% of water phase and 100% of water. The invention relates to revival grass skin-activating plant extract cream and a preparation method thereof, which are specially used for dry skin, multiple moisturizing components are cooperated to increase the effect, moisture is introduced into each cell of the skin, water is effectively locked and is matched with the skin cell to be activated, skin moisturizing circulation is formed, the skin is activated and regenerated, a water-in-oil preparation process is adopted, so that an oily film is formed on the surface of the skin, better moisturizing, softening and moistening effects are realized on the skin, on the other hand, a protection effect is realized, the external stimulation to the skin is prevented, the active components are prevented from being dissipated on the surface of the skin, and the active components are more extremely acted on the deep layer of the skin.

Description

Revival grass skin-activating plant extract cream and preparation method thereof

Technical Field

The invention relates to the technical field of skin care products, in particular to revived grass skin-activating plant extract cream and a preparation method thereof.

Background

The modern society works, the living pressure is increased, the air pollution is serious, the people feel addicted to stay up to night, and the skin is in an aging state of dryness, roughness, pigmentation and increased fine wrinkles without doing daily sun protection. On the other hand, with the aging, the ability of the human body to replenish new cells per se is reduced, and the functions of the systems of the whole body are reduced, so that the skin is slightly in an aging state such as roughness and wrinkle growth, and on the other hand, the skin is classified into 5 types of skin according to the moisture content of the skin, the secretion state of skin glands, and the like: dry skin, neutral skin, oily skin, sensitive skin and mixed skin are not selected, so that the skin care product has no effect when being used, the skin care products have different skin types and care key points, and the skin care products are also selected differently.

In the prior art, the skin-activating plant extract cream has a common use effect in the use process, the moisture content of dry skin stratum corneum is low easily in the use process, the skin-activating plant extract cream is sensitive to external stimulation, and wrinkles and pigment precipitates easily appear, so that the moisturizing effect is very important, Chinese patent application (CN201910044775.1) discloses a cell reviving grass cream and a preparation method thereof, only shows that the cell reviving grass cream activates cells and enhances the moisturizing effect of the skin by adding reviving factors and reviving grass extracts, does not care different skin types, and cannot achieve the good moisturizing effect in the use process of different skin types, and therefore, the reviving grass skin-activating plant extract cream and the preparation method thereof are provided to solve the problems.

Disclosure of Invention

Aiming at the defects of the prior art, the invention provides revived grass skin-activating plant extract cream and a preparation method thereof, and aims to solve the problems in the background art.

In order to achieve the purpose, the invention provides the following technical scheme: the resurrection grass skin-activating plant extract cream comprises the following raw materials in percentage by mass: 0.01-0.05% of undaria pinnatifida extract, 0.1-0.5% of osmin plant allergy relieving essence, 0.01-0.03% of alteromonas ferment product extract, 0.1-0.5% of Ardisia mollissima leaf/stem extract, 0.1-0.2% of ascorbic acid (vitamin C), 16-30% of oil phase, 18.55-38.4% of water phase and 100% of water.

A preparation method of revived grass skin-activating plant extract cream comprises the following steps:

s1, weighing the raw materials for the first time: weighing raw materials of each component in a required oil phase according to a proportion, and putting the raw materials into a beaker I for later use;

s2, preparation of oil phase mixture: heating the raw materials in the first beaker in the step S1 to 75-80 ℃ to completely dissolve, and weakly homogenizing for 1-2min to obtain the required oil phase mixture;

s3, weighing the raw materials for the second time: weighing raw materials of each component in the required water phase according to a proportion, and putting the raw materials into a beaker II for later use;

s4, preparation of aqueous phase mixture: heating the raw materials in the beaker II in the step S3 to 75-80 ℃ until the water phase in the beaker II is completely dissolved, keeping the temperature and stirring, cooling, adding the active ingredients, and stirring uniformly to obtain a water phase mixture;

s5, mixing of raw materials: adding the water phase mixture prepared in the step S4 into the oil phase mixture prepared in the step S2, and uniformly stirring at a certain temperature to prepare a required mixed raw material;

s6, preparation of revival grass skin-activating plant extract cream: opening weak homogenization on the mixed raw material obtained in the step S5 to enable the mixed raw material to have fine appearance to obtain uniform paste, and preparing the revived grass skin-activating plant extract cream;

s7, filling and checking: and (5) filling, inspecting and packaging the revived grass skin-activating plant extract cream prepared in the step S6.

Further optimizing the technical scheme, the oil phase comprises 1-5% of cyclopentadidimethyl siloxane, 2-3.5% of cyclohexasiloxane, 1-2% of buckeye double seed resin, 5-8% of polydimethylsiloxane, 1-2.5% of dimethiconol, 3.5-5% of Runemul WSI and 102.5-4% of GI CD.

Further optimizing the technical scheme, the water phase comprises 5-10% of glycerol, 1.5-3% of betaine, 0.05-0.15% of sodium hyaluronate, 8-12% of butanediol, 1-5% of propylene glycol, 0.1-0.25% of allantoin, 0.8-1.5% of magnesium sulfate, 1-2.5% of PEG/PPG/polytetramethylene glycol-8/5/3 glycerol, 0.5-1.5% of ethylhexyl glycerol, 0.5-2% of 1, 2-hexanediol, 0.1-0.5% of chlorphenesin and 100% of water.

Further optimizing the technical scheme, the Runemul WSI comprises the following components: PEG-10 polydimethylsiloxane, disteardimonium hectorite, and cyclopentadimethylsiloxane. The technical proposal is further optimized,

further optimizing the technical scheme, the GI CD-10 comprises the following components: stearyloxymethicone/dimethicone copolymer, dimethicone, and cyclopentadimethicone.

Further optimizing the technical scheme, the heat preservation and stirring time in the step S4 is 5-10min, the temperature for cooling is 40-45 ℃, and the certain temperature in the step S5 is 40-45 ℃.

Further optimizing the technical scheme, the weak homogenization condition in the step S2 and the step S6 is the homogenization speed of 1000-2500rpm/min, and the homogenization time in the step S6 is 3-5 min.

Advantageous effects

Compared with the prior art, the invention provides revived grass skin-activating plant extract cream and a preparation method thereof, and the revived grass skin-activating plant extract cream has the following beneficial effects:

1. the invention relates to resurrection grass skin-activating plant extract cream and a preparation method thereof, and the resurrection grass skin-activating plant extract cream is specially used for dry skin, accurate repair and scientific skin care, can quickly hold moisture by cooperating multiple moisture-retaining components to generate synergistic effect when meeting skin water, can guide the moisture into each cell of the skin, can strongly lock the water to be matched with the skin cell activation to form skin water nourishing circulation and enable the skin to activate and regenerate.

2. The invention relates to a revival grass skin-activating plant extract cream and a preparation method thereof, wherein, the extract of melaleuca mollissima leaves/stems is added, which can enhance the activity and metabolism of cells, accelerate the synthesis of type I collagen precursors in aging cells, obviously improve the moisture retention, elasticity and smoothness of skin, reduce the redness of skin, accelerate the healing of wounds and the tissue repair, meanwhile, the extract of alteromonas ferment products is extracted after being fermented by marine strains, can be dispersed on the horny layer on the surface of the skin, prevent the skin from drying, has good moisture retention property, increases the elasticity of the skin by promoting the synthesis of collagen, can stimulate the growth of skin collagenocyte, accelerate the healing of wounds, the addition of the undaria pinnatifida extract has the functions of anti-inflammation, effectively resisting allergy, diminishing inflammation and relieving the discomfort of the skin, can be used as an antioxidant, has the function of activating the skin and resisting wrinkles, and the addition of the, the multiple healing promoting components are compounded and cooperate, so that the healing promoting effect of the whole formula is superior, skin chap and wound are quickly repaired, a strong water locking function and a deep skin cell activating effect are brought, the skin is stimulated to be moisturized, the collagen regeneration is promoted, the skin elasticity is obviously improved, the young vitality of the skin is recovered, and the undaria pinnatifida extract is matched with the allergy relieving plant essence for relieving and moisturizing.

Drawings

FIG. 1 is a schematic diagram of the transdermal water dispersion loss measured at different times by a revived grass skin-activating plant extract cream and a preparation method thereof provided by the invention;

FIG. 2 is a schematic diagram of the skin elasticity increasing rate measured at different times by the revived grass skin-activating plant extract cream and the preparation method thereof provided by the invention;

fig. 3 is a flow schematic diagram of a revived grass skin-activating plant cream and a preparation method thereof.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

The first embodiment is as follows: referring to fig. 3, the invention discloses a revived grass skin-activating plant cream, which comprises the following raw materials in percentage by mass: 0.01% of undaria pinnatifida extract, 0.2% of osmin plant allergy-relieving essence, 0.01% of alteromonas ferment product extract, 0.2% of melaleuca molle leaf/stem extract, 0.1% of ascorbic acid (vitamin C), 2% of cyclopentadimethylsiloxane, 2% of cyclohexasiloxane, 1% of buckeye resin, 6% of polydimethylsiloxane, 1% of dimethiconol, 3.5% of Runemul WSI, GICD-103%, 8% of glycerol, 2% of betaine, 0.1% of sodium hyaluronate, 10% of butanediol, 3.5% of propylene glycol, 0.1-0.25% of allantoin, 1% of magnesium sulfate, 1% of PEG/PPG/polybutylene glycol-8/5/3 glycerol, 0.8% of ethylhexylglycerol, 1.5% of 1, 2-hexanediol, 0.35% of chlorphenesin and water to 100%.

s4, preparation of aqueous phase mixture: heating the raw materials in the beaker II in the step S3 to 75 ℃ until the water phase in the beaker II is completely dissolved, keeping the temperature and stirring, cooling, adding the active ingredients, and uniformly stirring to obtain a water phase mixture;

As a specific optimization scheme of this embodiment, the oil phase includes 1 to 5% of cyclopentadimethylsiloxane, 2 to 3.5% of cyclohexasiloxane, 1 to 2% of buckeye resin, 5 to 8% of polydimethylsiloxane, 1 to 2.5% of dimethiconol, 3.5 to 5% of runimul WSI, and 102.5 to 4% of GI CD-102.5.

As a specific optimization scheme of the embodiment, the water phase comprises 5-10% of glycerol, 1.5-3% of betaine, 0.05-0.15% of sodium hyaluronate, 8-12% of butanediol, 1-5% of propylene glycol, 0.1-0.25% of allantoin, 0.8-1.5% of magnesium sulfate, 1-2.5% of PEG/PPG/polytetramethylene glycol-8/5/3 glycerol, 0.5-1.5% of ethylhexyl glycerol, 0.5-2% of 1, 2-hexanediol, 0.1-0.5% of chlorphenesin and 100% of water.

As a specific optimization scheme of this embodiment, the ingredients of the runimul WSI are: PEG-10 polydimethylsiloxane, disteardimonium hectorite, and cyclopentadimethylsiloxane.

As a specific optimization scheme of this embodiment, the GI CD-10 comprises the following components: stearyloxymethicone/dimethicone copolymer, dimethicone, and cyclopentadimethicone.

As a specific optimization scheme of this embodiment, the time for maintaining the temperature and stirring in step S4 is 5min, the temperature for reducing the temperature is 40 ℃, and the certain temperature in step S5 is 40 ℃.

As a specific optimization scheme of this embodiment, the weak homogenization condition in step S2 and step S6 is a homogenization speed of 1000-.

Example two: referring to fig. 3, the invention discloses a revived grass skin-activating plant cream, which comprises the following raw materials in percentage by mass: 0.01% of undaria pinnatifida extract, 0.1% of osmin plant allergy-relieving essence, 0.01% of alteromonas ferment product extract, 0.1% of melaleuca molle leaf/stem extract, 0.1% of ascorbic acid (vitamin C), 1% of cyclopentadimethylsiloxane, 2% of cyclohexasiloxane, 1% of buckeye dill seed resin, 5% of polydimethylsiloxane, 1% of dimethiconol, 3.5% of Runemul WSI, 3.5% of GI CD-102.5%, 5% of glycerol, 1.5% of betaine, 0.05-0.15% of sodium hyaluronate, 8% of butanediol, 1% of propylene glycol, 0.1% of allantoin, 0.8% of magnesium sulfate, 1% of PEG/PPG/polytetramethylene glycol-8/5/3 glycerol, 1.5% of ethylhexyl glycerol, 0.5% of 1, 0.5% of 2-hexanediol, 0.5% of chlorphenesin and water to 100.

s4, preparation of aqueous phase mixture: heating the raw materials in the beaker II in the step S3 to 78 ℃ until the water phase in the beaker II is completely dissolved, keeping the temperature and stirring, cooling, adding the active ingredients, and uniformly stirring to obtain a water phase mixture;

As a specific optimization scheme of this embodiment, the time for maintaining the temperature and stirring in step S4 is 8min, the temperature for reducing the temperature is 42 ℃, and the certain temperature in step S5 is 42 ℃.

Example three: referring to fig. 3, the invention discloses a revived grass skin-activating plant cream, which comprises the following raw materials in percentage by mass: 0.05% of undaria pinnatifida extract, 0.5% of osmin plant allergy-relieving essence, 0.03% of alteromonas ferment product extract, 0.5% of melaleuca molle leaf/stem extract, 0.2% of ascorbic acid (vitamin C), 5% of cyclopentadimethylsiloxane, 3.5% of cyclohexasiloxane, 2% of buckeye diligena seed resin, 8% of polydimethylsiloxane, 2.5% of dimethiconol, 5% of Runemul WSI, 5% of GI CD-104, 5% to 10% of glycerol, 3% of betaine, 0.15% of sodium hyaluronate, 12% of butanediol, 5% of propylene glycol, 0.25% of allantoin, 1.5% of magnesium sulfate, 2.5% of PEG/PPG/polytetramethylene glycol-8/5/3 glycerol, 1.5% of ethylhexyl glycerol, 2% of 1, 2-hexanediol, 0.5% of chlorphenesin and water to 100%.

s2, preparation of oil phase mixture: heating the raw materials in the first beaker in the step S1 to 80 ℃ to completely dissolve, and weakly homogenizing for 2min to obtain the required oil phase mixture;

s4, preparation of aqueous phase mixture: heating the raw materials in the beaker II in the step S3 to 80 ℃ until the water phase in the beaker II is completely dissolved, keeping the temperature and stirring, cooling, adding the active ingredients, and stirring uniformly to obtain a water phase mixture;

As a specific optimization scheme of this embodiment, the time for maintaining the temperature and stirring in step S4 is 10min, the temperature for reducing the temperature is 45 ℃, and the certain temperature in step S5 is 45 ℃.

Experimental examples 1-3 and comparative examples 1-2 plant extracts were prepared as follows:

s5, mixing: adding the water phase mixture prepared in the step S4 into the oil phase mixture prepared in the step S2, and uniformly stirring at a certain temperature to prepare a required mixed raw material;

Comparative example 1 differs from example 1 in that the Artocarpus millettii leaf/stem extract, alteromonas ferment extract were not added.

Comparative example 2 is different from example 1 in that the undaria pinnatifida extract and the osmin plant hypomin essence are not added.

Comparative example 3 differs from example 1 in that Runemul WSI was not added as an emulsifier and 3% AVH30 was added as an emulsifier for the general oil-in-water cream preparation.

Control group: certain commercially available moisturizing cream

Determination of the amount of Water loss from the skin surface (TEW L)

30 volunteers of each experimental group, which are aged 19-55 years, are dry skin with dry skin and fine lines, the water loss of the skin of the 30 subjects before the application of each example, the comparative example and the control group and after the application for 1h, 2h and 4h is measured, and the mean value of TEW L is calculated, and the result is shown in figure 1.

And (3) testing environment: the room temperature is 22 +/-2 ℃, and the humidity is 47 +/-7%.

The instrument comprises the following steps: finland Delfin Vapometer percutaneous water loss measuring instrument

The smaller the value of the percutaneous water loss TEW L, the less the water loss, the stronger the water locking capacity, and on the contrary, the weaker the water locking capacity, the lower the TEW L value, the better the water locking effect, and the results are shown in figure 1.

As can be seen from FIG. 1, the revived grass skin-activating plant extract cream prepared in examples 1-3 has a significantly reduced TEW L value, reduces the rate of skin moisture loss, and effectively locks moisture to activate skin.

FIG. 1 Water Dispersion loss measured at different times

Skin elasticity efficacy verification: carrying out long-acting moisturizing tests of the plant extract creams and the control group moisturizing cream in examples 1-4 and comparative examples 1-3 on a subject, carrying out blank test on the subject by using an Elastimeter skin elasticity measuring instrument, measuring blank values, measuring skin elasticity 3, 7 and 10 days after smearing is started, and calculating the skin elasticity increase rate, wherein the results are shown in figure 2;

as can be seen from FIG. 2, the revival grass plant extracts prepared in examples 1-3 all increase the elasticity of the skin, all curves are raised, the elasticity of the skin is closely related to the moisture content in the horny layer, and the skin is more elastic when the horny layer is rich in moisture. Therefore, the revived grass skin-activating plant extract cream provided by the invention has a good moisturizing effect, the skin elasticity is obviously improved, and the young vitality of the skin is restored.

And (4) judging the standard: through comparison of the three embodiments, the best effect is the first embodiment, so that the selection of the first embodiment as the best embodiment, and the specific change of the amount also belongs to the protection scope of the technical scheme.

The invention has the beneficial effects that: the skin care cream is specially used for dry skin, is accurate in repair and scientific in skin care, can be used for dissolving water when meeting the skin, has multiple moisture retention components in a synergistic manner, can quickly grasp moisture, guides the moisture into each cell of the skin, effectively locks the water to be matched with the activation of the skin cells to form skin water nourishing circulation, enables the skin to be alive and regenerated, adopts a water-in-oil preparation process, enables the skin surface to form an oily film, and plays a better moisture retention, softening and moistening role on the skin, and plays a protective role on the other hand, thereby not only protecting the stimulation of the skin from the outside, but also protecting active components from being dissipated to the skin surface, and enabling the active components to be more extremely acted on the deep layer of; the invention adds the extract of the leaves/stems of the millettia speciosa, which can enhance the vitality and metabolism of cells, accelerate the synthesis of type I collagen precursors in aged cells, obviously improve the moisture retention, elasticity and smoothness of skin, relieve the skin redness, accelerate the wound healing and the tissue repair, simultaneously, the extract of the alteromonas fermentation product is extracted after being fermented by marine strains, can be dispersed on the horny layer on the surface of the skin, prevent the skin from being dry, has good moisture retention property, increases the skin elasticity by promoting the synthesis of collagen, can stimulate the growth of collagen fibroblasts of the skin, accelerate the wound healing, has the anti-inflammatory function, effectively resists allergy and inflammation, relieves the skin discomfort, can be used as an antioxidant, has the functions of activating skin and resisting wrinkles, and can improve the skin barrier function by adding the allergy-soothing essence of an European allergy-relieving plant, the multiple healing promoting components are compounded and cooperate, so that the healing promoting effect of the whole formula is superior, skin chap and wound are quickly repaired, a strong water locking function and a deep skin cell activating effect are brought, the skin is stimulated to be moisturized, the collagen regeneration is promoted, the skin elasticity is obviously improved, the young vitality of the skin is recovered, and the undaria pinnatifida extract is matched with the allergy relieving plant essence for relieving and moisturizing.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims

1. The revival grass skin-activating plant extract cream is characterized by comprising the following raw materials in percentage by mass: 0.01-0.05% of undaria pinnatifida extract, 0.1-0.5% of osmin plant allergy relieving essence, 0.01-0.03% of alteromonas ferment product extract, 0.1-0.5% of Ardisia mollissima leaf/stem extract, 0.1-0.2% of ascorbic acid (vitamin C), 16-30% of oil phase, 18.55-38.4% of water phase and 100% of water.

2. A preparation method of revived grass skin-activating plant extract cream comprises the following steps:

3. The revived grass skin-activating plant extract cream and the preparation method thereof as claimed in claim 2, wherein the oil phase comprises 1-5% of cyclopentadimethylsiloxane, 2-3.5% of cyclohexasiloxane, 1-2% of buckeye duplex seed resin, 5-8% of polydimethylsiloxane, 1-2.5% of dimethiconol, 3.5-5% of Runemul WSI and 102.5-4% of GI CD-102.5%.

4. The revival grass skin-activating plant extract cream and the preparation method thereof according to claim 2, characterized in that the water phase comprises 5-10% of glycerin, 1.5-3% of betaine, 0.05-0.15% of sodium hyaluronate, 8-12% of butanediol, 1-5% of propylene glycol, 0.1-0.25% of allantoin, 0.8-1.5% of magnesium sulfate, 1-2.5% of PEG/PPG/polytetramethylene glycol-8/5/3 glycerin, 0.5-1.5% of ethylhexylglycerin, 0.5-2% of 1, 2-hexanediol, 0.1-0.5% of chlorphenesin and 100% of water.

5. The revived grass skin-activating plant extract cream and the preparation method thereof as claimed in claim 3, wherein the Runemul WSI comprises the following components: PEG-10 polydimethylsiloxane, disteardimonium hectorite, and cyclopentadimethylsiloxane.

6. The revived grass skin-activating plant extract cream and the preparation method thereof according to claim 3, wherein the GICD-10 comprises the following components: stearyloxymethicone/dimethicone copolymer, dimethicone, and cyclopentadimethicone.

7. The revived grass skin-activating plant extract cream and the preparation method thereof as claimed in claim 2, wherein the time of heat preservation and stirring in the step S4 is 5-10min, the temperature of cooling is 40-45 ℃, and the certain temperature in the step S5 is 40-45 ℃.

8. The revived grass skin-activating plant extract cream and the preparation method thereof as claimed in claim 2, wherein the weak homogenization condition in step S2 and step S6 is a homogenization speed of 1000-2500rpm/min, and the homogenization time in step S6 is 3-5 min.