CN109706119A - 扩增造血干细胞的培养体系、方法及其用途 - Google Patents
扩增造血干细胞的培养体系、方法及其用途 Download PDFInfo
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- CN109706119A CN109706119A CN201810330298.0A CN201810330298A CN109706119A CN 109706119 A CN109706119 A CN 109706119A CN 201810330298 A CN201810330298 A CN 201810330298A CN 109706119 A CN109706119 A CN 109706119A
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/26—Flt-3 ligand (CD135L, flk-2 ligand)
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- Health & Medical Sciences (AREA)
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- General Engineering & Computer Science (AREA)
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Abstract
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Application Number | Priority Date | Filing Date | Title |
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CN201810330298.0A CN109706119B (zh) | 2018-04-13 | 2018-04-13 | 扩增造血干细胞的培养体系、方法及其用途 |
PCT/CN2018/083216 WO2019196128A1 (zh) | 2018-04-13 | 2018-04-16 | 扩增造血干细胞的培养体系、方法及其用途 |
PCT/CN2019/081854 WO2019196816A1 (zh) | 2018-04-13 | 2019-04-09 | 丁酸钠的用途及含有丁酸钠的培养体系 |
CN201980001861.2A CN110799641B (zh) | 2018-04-13 | 2019-04-09 | 丁酸钠的用途及含有丁酸钠的培养体系 |
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CN201810330298.0A CN109706119B (zh) | 2018-04-13 | 2018-04-13 | 扩增造血干细胞的培养体系、方法及其用途 |
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CN109706119A true CN109706119A (zh) | 2019-05-03 |
CN109706119B CN109706119B (zh) | 2020-11-27 |
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WO (1) | WO2019196128A1 (zh) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110951686A (zh) * | 2019-11-14 | 2020-04-03 | 武汉济源高科技有限公司 | 一种造血干细胞体外扩增培养体系和方法 |
CN114736862A (zh) * | 2022-05-18 | 2022-07-12 | 诺航生物技术研究院徐州有限公司 | 一种造血干细胞培养基和造血干细胞的体外扩增方法 |
CN115927169A (zh) * | 2022-10-11 | 2023-04-07 | 再造再生医学科技(杭州)有限公司 | 用于扩增cd34+造血干细胞的培养液和体外扩增cd34+造血干细胞的方法 |
CN114736862B (zh) * | 2022-05-18 | 2024-05-28 | 诺航生物技术研究院徐州有限公司 | 一种造血干细胞培养基和造血干细胞的体外扩增方法 |
Citations (1)
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CN106455542A (zh) * | 2014-03-26 | 2017-02-22 | 布里格姆及妇女医院股份有限公司 | 用于人造血干/祖细胞的离体扩增的组合物和方法 |
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RU2635317C2 (ru) * | 2009-10-19 | 2017-11-10 | Тристем Трейдинг (Сайпрес) Лимитед | Лечение с применением перепрограммированных зрелых и дифференцированных клеток |
DK3035798T3 (en) * | 2013-08-20 | 2018-11-19 | Univ Yeditepe | CELL CRYO-CONSERVATION MEDIUM ADDED TO DRILL |
CN104419683A (zh) * | 2013-09-10 | 2015-03-18 | 中国科学院生物物理研究所 | 制备范可尼贫血症患者自体诱导多能干细胞的方法及其应用 |
CN103740757B (zh) * | 2014-01-21 | 2016-04-20 | 中国科学院生物物理研究所 | 一种利用重编程制备猪神经干细胞的方法 |
-
2018
- 2018-04-13 CN CN201810330298.0A patent/CN109706119B/zh active Active
- 2018-04-16 WO PCT/CN2018/083216 patent/WO2019196128A1/zh active Application Filing
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106455542A (zh) * | 2014-03-26 | 2017-02-22 | 布里格姆及妇女医院股份有限公司 | 用于人造血干/祖细胞的离体扩增的组合物和方法 |
Non-Patent Citations (2)
Title |
---|
MARINA TARUNINA 等: ""A Novel High-Throughput Screening Platform Reveals an Optimized Cytokine Formulation for Human Hematopoietic Progenitor Cell Expansion"", 《STEM CELLS AND DEVELOPMENT》 * |
范洁 等: ""重组人体干细胞因子的表达、复性、纯化及其对脐带血干细胞体外扩增作用研究"", 《实用临床医学杂志》 * |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110951686A (zh) * | 2019-11-14 | 2020-04-03 | 武汉济源高科技有限公司 | 一种造血干细胞体外扩增培养体系和方法 |
CN114736862A (zh) * | 2022-05-18 | 2022-07-12 | 诺航生物技术研究院徐州有限公司 | 一种造血干细胞培养基和造血干细胞的体外扩增方法 |
CN114736862B (zh) * | 2022-05-18 | 2024-05-28 | 诺航生物技术研究院徐州有限公司 | 一种造血干细胞培养基和造血干细胞的体外扩增方法 |
CN115927169A (zh) * | 2022-10-11 | 2023-04-07 | 再造再生医学科技(杭州)有限公司 | 用于扩增cd34+造血干细胞的培养液和体外扩增cd34+造血干细胞的方法 |
CN115927169B (zh) * | 2022-10-11 | 2023-08-11 | 再造再生医学科技(杭州)有限公司 | 用于扩增cd34+造血干细胞的培养液和体外扩增cd34+造血干细胞的方法 |
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WO2019196128A1 (zh) | 2019-10-17 |
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