CN109575049B - Iap蛋白的二价抑制剂和使用其的治疗方法 - Google Patents

Iap蛋白的二价抑制剂和使用其的治疗方法 Download PDF

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CN109575049B
CN109575049B CN201811229870.0A CN201811229870A CN109575049B CN 109575049 B CN109575049 B CN 109575049B CN 201811229870 A CN201811229870 A CN 201811229870A CN 109575049 B CN109575049 B CN 109575049B
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iap
cancer
compound
apoptosis
cell
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CN109575049A (zh
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S·王
R·盛
H·孙
L·刘
J·卢
D·麦凯克恩
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University of Michigan Ann Arbor
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CN201811229870.0A 2012-08-23 2013-08-16 Iap蛋白的二价抑制剂和使用其的治疗方法 Active CN109575049B (zh)

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CN107987083A (zh) * 2017-11-24 2018-05-04 江苏亚盛医药开发有限公司 用于治疗和/或预防与肝炎病毒相关的疾病或病症的双二氮杂双环化合物
EP4512407A3 (en) 2018-07-13 2025-09-24 F. Hoffmann-La Roche AG Oligonucleotides for modulating rtel1 expression
WO2020027225A1 (ja) 2018-07-31 2020-02-06 ファイメクス株式会社 複素環化合物
TW202012411A (zh) * 2018-07-31 2020-04-01 大陸商蘇州亞盛藥業有限公司 Iap抑制劑與免疫檢查點分子調節劑的組合用於治療癌症的方法
CN113453678A (zh) 2018-11-26 2021-09-28 德彪药业国际股份公司 Hiv感染的联合治疗
US10870663B2 (en) 2018-11-30 2020-12-22 Glaxosmithkline Intellectual Property Development Limited Compounds useful in HIV therapy
CA3148504A1 (en) 2019-08-08 2021-02-11 Institute For Cancer Research D/B/A/ The Research Institute Of Fox Chase Cancer Center Combination therapy for treatment of cancer
MX2022003628A (es) 2019-09-25 2022-07-21 Debiopharm Int Sa Regímenes de dosificación para el tratamiento de pacientes con carcinoma de células escamosas avanzado localmente.
CN112891510A (zh) * 2019-11-19 2021-06-04 苏州亚盛药业有限公司 采用iap抑制剂的治疗方法
US20230029259A1 (en) * 2019-12-02 2023-01-26 Ascentage Pharma (Suzhou) Co., Ltd. Combination of iap inhibitors and parp or mek inhibitors or other chemotherapeutic agents
WO2021110136A1 (en) * 2019-12-04 2021-06-10 Ascentage Pharma (Suzhou) Co., Ltd. Pharmaceutical combination and use thereof
CN114828852A (zh) 2019-12-24 2022-07-29 豪夫迈·罗氏有限公司 用于治疗hbv的靶向hbv的抗病毒药剂和/或免疫调节剂的药物组合
US20230078120A1 (en) * 2020-05-04 2023-03-16 Ascentage Pharma (Suzhou) Co.,Ltd. Methods for Treating Coronavirus Infections
WO2022012671A1 (en) * 2020-07-16 2022-01-20 Ascentage Pharma (Suzhou) Co., Ltd. The crystalline forms or amorphous forms of bisdiazabicyclic compounds or salts thereof
CN116963732A (zh) * 2021-02-23 2023-10-27 苏州亚盛药业有限公司 药物组合物及其制备方法
EP4382126A4 (en) 2021-08-02 2025-07-30 Ascentage Pharma Suzhou Co Ltd PHARMACEUTICAL COMBINATION AND ITS USE
WO2023056069A1 (en) 2021-09-30 2023-04-06 Angiex, Inc. Degrader-antibody conjugates and methods of using same
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CA2882496A1 (en) 2014-02-27
JP2015528447A (ja) 2015-09-28
CN109485662B (zh) 2021-12-21
HK1211030A1 (en) 2016-05-13
EP2888265A1 (en) 2015-07-01
EP2888265A4 (en) 2016-01-27
KR102111704B1 (ko) 2020-05-15
CA2882496C (en) 2020-07-14
US8883771B2 (en) 2014-11-11
ES2654623T3 (es) 2018-02-14
WO2014031487A8 (en) 2014-05-30
CN104718209A (zh) 2015-06-17
RU2649975C2 (ru) 2018-04-06
AU2013306087A1 (en) 2015-03-12
US20140057924A1 (en) 2014-02-27
WO2014031487A1 (en) 2014-02-27
EP2888265B1 (en) 2017-10-11
CN109575049A (zh) 2019-04-05
KR20150044937A (ko) 2015-04-27
MX2015002371A (es) 2015-10-05
KR102237888B1 (ko) 2021-04-07
RU2015107552A (ru) 2016-10-10
MX366130B (es) 2019-06-28
KR20200054334A (ko) 2020-05-19
JP6247298B2 (ja) 2017-12-13
AU2013306087B2 (en) 2017-08-10

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