CN108935962A - A kind of pulvis and preparation method thereof taking off mould protect liver for livestock and poultry - Google Patents

A kind of pulvis and preparation method thereof taking off mould protect liver for livestock and poultry Download PDF

Info

Publication number
CN108935962A
CN108935962A CN201811153351.0A CN201811153351A CN108935962A CN 108935962 A CN108935962 A CN 108935962A CN 201811153351 A CN201811153351 A CN 201811153351A CN 108935962 A CN108935962 A CN 108935962A
Authority
CN
China
Prior art keywords
fermentation
pulvis
livestock
preparation
negative pressure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201811153351.0A
Other languages
Chinese (zh)
Inventor
潘慧青
张炎达
赵军
杨荣平
李珠金
吴建华
林贺桂
赵齐
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BRADY FUJIAN PHARMACEUTICAL Co
Original Assignee
BRADY FUJIAN PHARMACEUTICAL Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BRADY FUJIAN PHARMACEUTICAL Co filed Critical BRADY FUJIAN PHARMACEUTICAL Co
Priority to CN201811153351.0A priority Critical patent/CN108935962A/en
Publication of CN108935962A publication Critical patent/CN108935962A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/10Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/12Animal feeding-stuffs obtained by microbiological or biochemical processes by fermentation of natural products, e.g. of vegetable material, animal waste material or biomass
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/10Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A23K10/18Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/142Amino acids; Derivatives thereof
    • A23K20/147Polymeric derivatives, e.g. peptides or proteins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/163Sugars; Polysaccharides
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/174Vitamins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/189Enzymes
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/20Inorganic substances, e.g. oligoelements
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/30Feeding-stuffs specially adapted for particular animals for swines
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23NMACHINES OR APPARATUS FOR TREATING HARVESTED FRUIT, VEGETABLES OR FLOWER BULBS IN BULK, NOT OTHERWISE PROVIDED FOR; PEELING VEGETABLES OR FRUIT IN BULK; APPARATUS FOR PREPARING ANIMAL FEEDING- STUFFS
    • A23N17/00Apparatus specially adapted for preparing animal feeding-stuffs
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23NMACHINES OR APPARATUS FOR TREATING HARVESTED FRUIT, VEGETABLES OR FLOWER BULBS IN BULK, NOT OTHERWISE PROVIDED FOR; PEELING VEGETABLES OR FRUIT IN BULK; APPARATUS FOR PREPARING ANIMAL FEEDING- STUFFS
    • A23N17/00Apparatus specially adapted for preparing animal feeding-stuffs
    • A23N17/007Apparatus specially adapted for preparing animal feeding-stuffs for mixing feeding-stuff components
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/36Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482Cassia, e.g. golden shower tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F29/00Mixers with rotating receptacles
    • B01F29/60Mixers with rotating receptacles rotating about a horizontal or inclined axis, e.g. drum mixers
    • B01F29/62Mixers with rotating receptacles rotating about a horizontal or inclined axis, e.g. drum mixers without bars, i.e. without mixing elements; characterised by the shape or cross section of the receptacle, e.g. of Y-, Z-, S- or X- shape; with cylindrical receptacles rotating about an axis at an angle to their longitudinal axis
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/20Measuring; Control or regulation
    • B01F35/21Measuring
    • B01F35/214Measuring characterised by the means for measuring
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B9/00Cleaning hollow articles by methods or apparatus specially adapted thereto 
    • B08B9/08Cleaning containers, e.g. tanks
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00Lactic or propionic acid bacteria
    • A23V2400/11Lactobacillus
    • A23V2400/169Plantarum
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00Lactic or propionic acid bacteria
    • A23V2400/21Streptococcus, lactococcus
    • A23V2400/225Faecalis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/19Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/30Driving arrangements; Transmissions; Couplings; Brakes
    • B01F2035/35Use of other general mechanical engineering elements in mixing devices
    • B01F2035/351Sealings

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Animal Husbandry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physiology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Sustainable Development (AREA)
  • Birds (AREA)
  • Mechanical Engineering (AREA)
  • Neurosurgery (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention belongs to additive for farm animal feed production fields, disclose a kind of pulvis and preparation method thereof that mould protect liver is taken off for livestock and poultry.Be to be made in terms of 100% of each raw material of following mass percentages by the sum of mass percentage: fermented type Chinese herbal medicine extract powder 15 ~ 20%, complex enzyme 5 ~ 10%, multi-vitamins 5 ~ 10%, reductive glutathione 1 ~ 5%, compound probiotic bacterium powder 5 ~ 10%, surplus are complex carrier.Product formula disclosed by the invention improves in conjunction with the mixing degree that pulvis material mixing device is not only conducive to product and reduces oxygen sensitivity loss of material, product disclosed simultaneously has effects that in livestock and poultry cultivation that cultivated animals body is intracorporal and takes off mould and protect liver pair, beneficial to improving the resistivity in animal feeding link to mycotoxin, it is conducive to improve breeding efficiency.

Description

A kind of pulvis and preparation method thereof taking off mould protect liver for livestock and poultry
Technical field
The invention belongs to additive for farm animal feed production fields, and in particular to it is a kind of for livestock and poultry take off mould protect liver pulvis and Preparation method.
Background technique
Mycotoxin is the virose secondary metabolite of tool that mould generates in grown on matrix reproductive process, science Boundary is earliest in Britain turkey because of hepatopathy event caused by being polluted by it to the harm of cultivated animals to mycotoxin.According to the United Nations Food and agricultural organization (FAO) estimation, the whole world have 25% cereal by the pollution of mycotoxin, to give grain-production in varying degrees every year Person, animal husbandry and feed industry cause huge economic loss.
The Mycotoxins in Feed influence most basic to livestock and poultry is to reduce feed intake, reduces feed conversion rate, keeps livestock and poultry raw Performance is produced to substantially reduce;Meanwhile certain mycotoxins have oxidative damage toxicity, cause to damage to target tissue and target organ, break Antioxidant Enzyme Systems in bad body generate a series of influences to animal body;In addition, mycotoxin be able to suppress DNA, RNA and The synthesis of protein, reduces immunologic function of livestock and birds, to reduce livestock and poultry disease resistance and growth performance, to farm cause through Ji loss.
It mainly include at present physical method, bioanalysis and chemistry for the method for mycotoxin is removed in livestock and poultry cultivation link Method shows that its effect all has different and the low problem of effect ideality, especially object according to existing clinical test results Detoxicity method is managed, nutriment is sloughed with not only having sloughed toxin also non-selectivity, nutrition is caused to waste.Therefore it is badly in need of one in the market Kind compound de- removing mildew takes off mould class product substitute single-element in the market, but according to market survey as a result, it has been found that, First present existing compound de- removing mildew is a variety of single simple superposition and compounding for taking off mould class products material, be second Functional defect, i.e. such product only embody a concentrated reflection of the liver for removing mycotoxin in animal intestinal tract and being not concerned with animal body Function problem, and liver is exactly maximum and most important organ-tissue in animal body body.Therefore, for one kind can take off it is mould again Can liver protecting novel fodder additive will become livestock-raising industry new direction.
Meanwhile mould class product is taken off with existing market according to the literature, it is found that the preparation classification of Chinese herbal medicine is relatively limited, It more there are no the preparation of Chinese herbal medicine crude drug, and most direct utilizations for concentrating on Chinese herbal medicine, responding time are slow.How medium-height grass is sought The Efficient utilization method of medicine effective substance will influence the function and effect of product in future huge.In addition, being produced for existing removing toxic substances How product ensure that not oxidized destroy is also following to process equipment and technique to some oxygen sensitivity substances in product processing Test even more ensures the key of product quality.
Summary of the invention
In view of the above-mentioned defects in the prior art with deficiency, the purpose of the present invention is to provide one kind to take off mould protect liver for livestock and poultry Pulvis and preparation method thereof.
To achieve the above object, the technical solution adopted by the present invention is as follows:
A kind of pulvis taking off mould protect liver for livestock and poultry is in terms of 100%, by following mass percentages by the sum of mass percentage Each raw material be made: fermented type Chinese herbal medicine extract powder 15 ~ 20%, complex enzyme 5 ~ 10%, multi-vitamins 5 ~ 10%, reproducibility paddy The sweet peptide 1 ~ 5% of Guang, compound probiotic bacterium powder 5 ~ 10%, surplus are complex carrier;
The complex enzyme is by glucose oxidase and protease (2 ~ 5) in mass ratio: 1 mixes;
The multi-vitamins are by vitamin C, vitamin A and vitamin E (1 ~ 5) in mass ratio: (1 ~ 3): (1 ~ 2) mixing and At;
The compound probiotic bacterium powder is by taking off mould class probiotics and the health-related probiotics of enteron aisle (1 ~ 5) in mass ratio: 1 mixing and At, it is described that take off mould class probiotics be commercially available bacillus subtilis, the health-related probiotics of enteron aisle by commercial plant lactobacillus and Enterococcus faecalis BD-1 (1 ~ 3) in mass ratio: 1 mixes;
The complex carrier is by active carbon-bamboo fibre compound and DEXTROSE ANHYDROUS in mass ratio 1: (5 ~ 20) mix, institute Stating active carbon-bamboo fibre compound is active carbon and bamboo fibre active carbon in mass ratio: bamboo fibre=1: the mixing of (1 ~ 5) composition Object;
The fermented type Chinese herbal medicine extract powder prepares as follows:
S1, the preparation of clostridium butyricum RCM-2 fermentation seed liquid:
Using method described in number of patent application CN201710559482.8, clostridium butyricum RCM-2 fermentation seed liquid is made;
S2, the preparation of mixed fermentation strain:
In terms of quality percent by volume g/mL, commercially available water-soluble enterococcus faecalis bacterium powder is thrown to butyric acid according to 5 ~ 10% ratio In clostridium RCM-2 fermentation seed liquid, dissolution is mixed, and mixed fermentation strain is made;
S3, fermentation substrate preparation:
The dry material of radix pseudostellariae, cassia seed, Radix Astragali, radix scutellariae, white folder leaf of bamboo five tastes Chinese herbal medicine is crushed respectively;Then with quality hundred Divide the sum of content for 100% meter, takes radix pseudostellariae 30 ~ 45%, cassia seed 15 ~ 30%, Radix Astragali 15 ~ 25%, radix scutellariae 15 ~ 20%, the white folder leaf of bamboo 10 ~ 15%, it is uniformly mixed, fermentation substrate is made;
S4, the preparation of radix pseudostellariae extract:
Using method described in number of patent application CN201610759126.6, radix pseudostellariae extract is made;
S5, radix pseudostellariae extract liquid fermentation:
The water that the radix pseudostellariae extract that S4 is obtained adds 1 ~ 1.5 mass times is diluted, adjusting pH value to 6.0 ~ 6.5, then With volume percentage, the mixed fermentation strain of S2 preparation is inoculated in the radix pseudostellariae after dilution according to 3 ~ 7% inoculative proportion and is extracted It takes and carries out static fermentation in object, the fermentation termination time is 40 ~ 48 h;
S6, fermentation substrate solid state fermentation:
By percentage to the quality, the fermentation of S3 preparation is added according to 30 ~ 40% ratio using the fermentation liquid of S5 preparation as seed liquor In matrix, after mixing, direct packaging is in progress solid stationary fermentation in fermentation bag, when fermentation temperature is 30 ~ 37 DEG C, ferments Between be 1 ~ 2 week;
S7, effective substance extract:
When S6 fermentation termination, fermentation bag to be opened, the water of fermentation material plus 10 ~ 15 mass times is extracted, Extracting temperature is 90 ~ 100 DEG C, extraction time be 3 ~ 5 h, extracting solution is using three-stage filtration system described in number of patent application CN201610759126.6 System is filtered, filtered liquid in terms of quality percent by volume g/mL, directly addition account for its 5 ~ 10% auxiliary material glucose into Row spray drying, is made fermented type Chinese herbal medicine extract powder.
Preferably, 8000 ~ 10000 U/g of enzyme activity of glucose oxidase, the enzyme activity of protease are 50000 ~ 100000 U/ g;The potency of vitamin A is 500000-1000000 IU/g, and the potency of vitamin E is 500 ~ 1000 IU/g;Commercially available withered grass bud Viable count >=1.0 × 10 of spore bacillus8CFU/g, viable count >=1.0 × 10 of commercial plant lactobacillus8CFU/g, enterococcus faecalis Viable count >=1.0 × 10 of BD-18CFU/g, viable count >=1.0 × 10 of commercially available water solubility enterococcus faecalis bacterium powder8CFU/g。
Preferably, the active carbon-bamboo fibre compound prepares as follows:
Dry bamboo pole is cut into the block of the equal 0.1 ~ 1cm of length and width first, then crushes block, it is fine to obtain bamboo Dimension;
According to quality than active carbon: bamboo fibre=1: (1 ~ 5) weighs two kinds of materials respectively, first sprays to bamboo fibre after the completion of weighing The water of its mass percent 3 ~ 5% is accounted for, then it is successively quick-fried by steam that double section Steam explosion treatments are carried out after two kinds of materials are merged Tear manages I and Steam explosion treatment II, and double sections of Steam explosion treatment interval times are 2 ~ 5min;After double sections of Steam explosion treatments Material is dried again, is crushed again after to be dried, and active carbon-bamboo fibre compound is made after crossing 80 ~ 100 meshes;
Wherein, the condition of Steam explosion treatment I are as follows: explosion chamber coefficient is 0.8 ~ 0.9, explosion steam pressure up to 0.6 ~ 0.8MPa, explosion pressure maintaining handle the time as 5 ~ 10min, and blasting time is not higher than 0.00875s;The condition of Steam explosion treatment II Are as follows: blasting gear with cavity explosion treatment, protect up to 1.5 ~ 2.5MPa, explosion by explosion steam pressure on the same stage with Steam explosion treatment I The pressure processing time is 10 ~ 30s, and blasting time is not higher than 0.00875s.
A kind of preparation method for the pulvis taking off mould protect liver for livestock and poultry: hair is launched first into pulvis material mixing device Ferment type Chinese herbal medicine extract powder, compound probiotic bacterium powder, complex carrier are finally launched complex enzyme respectively again, multi-vitamins, are gone back Originality glutathione, is finally mixed, and the pulvis that mould protect liver is taken off for livestock and poultry is made.
Preferably, the pulvis material mixing device includes rack, hybrid agent, control main body, negative pressure main body;
The rack includes the vertical support that a horizontal base and two are respectively and vertically fixed at pedestal left and right ends, pedestal and Support inner hollow;A back-up roller wheel bearing is respectively fixedly connected on two opposite lateral walls of two supports;
The hybrid agent includes a V-type cylinder, which is docked by two cylindrical tubes, a cylindrical tube top Portion is equipped with feed inlet and feed inlet covers, and is respectively equipped with compatible collar extension and latch closure on feed inlet capping and feed inlet;V-type cylinder The on both sides of the middle of body is respectively fixedly connected with a shaft, and two shafts are respectively provided in the back-up roller wheel bearing of respective side;V-type cylinder Bottom is equipped with discharge port, and discharge port is equipped with valve;
The control main body includes motor, integrated control case, two infrared induction probes, and motor and the fixation of integrated control cabinet are set It sets inside same support and the output end of motor is connect with ipsilateral shaft, input terminal is electrically connected with integrated control case, integrate The control panel of control cabinet exposes to the outer surface of support, and the power supply line of integrated control case is drawn to carrier exterior, two infrared Line inductive probe is respectively fixedly disposed on two opposite lateral walls of two supports below back-up roller wheel bearing;The control panel It is equipped with power supply indicator, run indicator, start button, scram button, positive inching button, negative sense inching button, revolving speed Controller, intelligent digital counter;Two infrared induction probe parallel connections are electrically connected to intelligent digital counter;
The negative pressure main body includes the fixed blind flange being located at the top of another cylindrical tube, is fixed with vacuum on blind flange Pump, intelligent digital negative pressure controller, battery, the exhaust valve for carrying charging jack, vacuum pump and intelligent digital negative pressure controller are each It is electrically connected from battery, is connected between vacuum pump and intelligent digital negative pressure controller by signal wire;Vacuum pump, intelligent digital are negative Pressure controller, exhaust valve bottom respectively connect a hollow tubing conductor and communicate with V-type cylinder lumen, the hollow tubing conductor being connected with vacuum pump Bottom is equipped with cooling gas check valve;One negative pressure protective cover of blind flange bottom detachable connection, the bottom end of three hollow tubing conductors and Cooling gas check valve is respectively positioned in negative pressure protective cover;The negative pressure protective cover upper section is cylindrical, lower section is in back taper, and back taper is negative Several stomatas have been evenly arranged on pressure protective cover, have been fitted with several layers non-woven fabrics, nonwoven outside back taper negative pressure protective cover Cloth is pressed on cylindrical negative pressure protective cover by annulus.
Preferably, the detachable connection between blind flange and negative pressure protective cover is to be threadedly coupled, i.e. flange pan bottom is set There are internal screw thread counterbore, cylindrical negative pressure protective cover top to be equipped with external screw thread, the external screw thread precession flange of cylindrical negative pressure protective cover In the internal screw thread of pan bottom counterbore;Pore opening is 1 ~ 5mm, and the number of plies of non-woven fabrics is 1 ~ 5 layer.
Preferably, the pulvis material mixing device further includes sampling main body and/or cleaning main body;
The sampling main body includes concave groove, and the bottom wall fitting of concave groove is fixed on the inner sidewall of V-type cylinder and concave The lower end of slot is abutted against with discharge port;V-type cylinder is penetrated on the bottom wall of concave groove is fixedly uniformly arranged with several sample taps;Institute Stating sample tap includes circular base, the outer silk of clip, and one end of circular base is fixed in concave groove bottom wall, the other end penetrates V-type cylinder extends outwardly and the end is connect with the threaded threaded one end of the outer silk of clip, and the other end of the outer silk of clip passes through card Hoop is connected with blocking film;
The cleaning main body includes two tubular inlets, and two inlets are respectively provided at two cylindrical tube top sidewalls On, the bottom end of two inlets is respectively connected with rotary wash ball, detachable on the cylindrical tube inner wall below two inlets Formula is connected with closed protective cover, and the closed protective cover is cylinder, the bottom end of two inlets and rotary wash ball It is respectively positioned in closed protective cover.
Preferably, ring washer and close is successively arranged between threaded one end of the outer silk of circular base and clip from inside to outside Mounting;Detachable connection between cylindrical tube and closed protective cover is to be threadedly coupled, i.e. cylindrical tube inner wall is equipped with Internal screw thread counterbore, closed protective cover top are equipped with external screw thread, and the external screw thread precession cylindrical tube inner wall of closed protective cover is heavy In the internal screw thread in hole;Several sample taps are equally arranged along concave groove bottom wall direction, 5 ~ 15 cm of spacing size, bottom The vertical height of sample tap and discharge port is 10 ~ 20 cm.
Preferably, the sampling main body further include with the matching used probe tube of sample tap, the front end of probe tube offers Sample inlet, rear end are screw thread handle, and sample inlet is integrally in flat but front end in pointed, from sample inlet on probe tube Rear end opens up one section of gap backwards, is equipped with circular baffle plate compatible with probe tube in gap rear position inside probe tube.
Preferably, gap width is 5mm ~ 2cm, and the horizontal space between gap and circular baffle plate is 3 ~ 6 cm.
The utility model has the advantages that
1, product formula disclosed by the invention is improved and is dropped in conjunction with the mixing degree that pulvis material mixing device is not only conducive to product Hypoxic sensitivity loss of material, while disclosed product has in livestock and poultry cultivation that cultivated animals body is intracorporal takes off mould and protect liver Double effects are conducive to improve breeding efficiency beneficial to improving the resistivity in animal feeding link to mycotoxin.
2, pulvis material mixing device of the present invention can be realized livestock and poultry medicinal powder powder material mixing in place, continuous quick object The function of material sampling, the static cleaning of inner barrel in place;
3, stationary internal cleans the ability of barrel, more traditional rock and roll in place after pulvis material mixing device material mixing of the present invention Formula cleaning, significantly reduces equipment running wastage;
4, pulvis material mixing device of the present invention can realize the quick continuous sampling of product and finished product among material, be greatly improved and take Sample efficiency also improves the sampling accuracy of mixed material;
5, pulvis material mixing device of the present invention can also realize mixing and sampling overall process vacuum cavitations, overcome mixing with Material loss caused by dust escapes in sampling process is big and particulate matter space-pollution problem;
6, pulvis material mixing device control main body of the present invention controls the revolving speed of adjustment V-type cylinder with rotational speed governor, with intelligence The revolution of energy digital display counter, infrared induction probe control V-type cylinder, can run after the completion of revolving speed and revolution setting and set Standby, when reaching revolution setting value, equipment forward direction is vertical, out of service, and the function and other same categories of device are mixed with time control Material operation is different, and V-type cylinder is in non-positive vertical stop position and also needs manually when overcoming the operation stopping of other same categories of device The drawbacks of crawl adjusting position;
7, pulvis material mixing device tightness of the present invention is high, and reduction is by outside contamination and the probability to outside contamination, drop Low loss of material rate, and dust leakage is substantially reduced, harm to the human body is reduced, while negative pressure device can also examination device and its portion Part whether leakage problem, be conducive to plant maintenance, also be conducive to different batches product conservation of matter.
Detailed description of the invention
Fig. 1: the overall structure diagram of pulvis material mixing device in the present invention;
Fig. 2: the decomposition texture schematic diagram of sample tap;
Fig. 3: the structural schematic diagram of probe tube;
Fig. 4: the structural schematic diagram of main body is cleaned;
Fig. 5: the overlooking structure diagram of negative pressure main body;
Fig. 6: the schematic view of the front view of negative pressure main body;
Fig. 7: the structural schematic diagram of negative pressure protective cover;
Description of symbols: 1- pedestal, 2- support, 3- back-up roller wheel bearing, 4-V type tube body, 5- feed inlet, 6- feed inlet envelope Lid, 7- collar extension, 8- latch closure, 9- seal washer, 10- shaft, 11- discharge port, 12- valve, 13- motor, 14- integrated control case, 15- power supply line, 16- infrared induction probe, 17- power supply indicator, 18- run indicator, 19- start button, 20- emergency stop are pressed Button, 21- forward direction inching button, 22- negative sense inching button, 23- rotational speed governor, 24- intelligent digital counter, 25- concave groove, 26- sample tap, 261- circular base, the outer silk of 262- clip, 263- blocking film, 264- ring washer, 265- diaphragm seal, 27- sampling Pipe, 271- sample inlet, 272- screw thread handle, the gap 273-, 274- circular baffle plate, 28- inlet, 29- rotary wash ball, The closed protective cover of 30-, 31- blind flange, 32- vacuum pump, 33- intelligent digital negative pressure controller, 34- battery, 35- exhaust valve, 36- hollow tubing conductor, 37- cooling gas check valve, 38- negative pressure protective cover, 39- annulus.
Specific embodiment
To keep the present invention clearer, clear, technical solution of the present invention is further described below.It should manage Solution, the specific embodiments described herein are merely illustrative of the present invention, is not intended to limit the present invention.
In following embodiments, the enzyme activity of glucose oxidase is 8000 U/g, and proteinase activity is 50000 U/g;Dimension life The potency of plain A is 500000 IU/g, and the potency of vitamin E is 500 IU/g;The viable count of commercially available bacillus subtilis is 1.0 ×108 CFU/g, the viable count of commercial plant lactobacillus are 1.0 × 108 The viable count of CFU/g, enterococcus faecalis BD-1 be 1.0 × 108 The viable count of CFU/g, commercially available water solubility enterococcus faecalis bacterium powder are 1.0 × 108 CFU/g;Enterococcus faecalis BD-1 is applicant Enterococcus faecalis disclosed in the patent application (application number: CN201710559483.2) submitted on July 11st, 2017 (Enterococcus faecalis) BD-1, and the bacterial strain is preserved in China typical culture collection center, address: Wuhan City Wuchang Luo Jia Shan, preservation date: on July 7th, 2017;Deposit number: CCTCC NO:M2017416.
Embodiment 1
A kind of pulvis taking off mould protect liver for livestock and poultry is in terms of 100%, by following mass percentages by the sum of mass percentage Each raw material be made: fermented type Chinese herbal medicine extract powder 20%, complex enzyme 8%, multi-vitamins 10%, reductive glutathione 5%, Compound probiotic bacterium powder 9%, surplus are complex carrier;
The complex enzyme is mixed by glucose oxidase and protease in mass ratio 4: 1;
The multi-vitamins are mixed by vitamin C, vitamin A and vitamin E in mass ratio 5: 3: 2;
The compound probiotic bacterium powder is mixed by taking off mould class probiotics and the health-related probiotics of enteron aisle in mass ratio 3: 1, institute It states and takes off mould class probiotics for commercially available bacillus subtilis, the health-related probiotics of enteron aisle is by commercial plant lactobacillus and excrement intestines ball Bacterium BD-1 in mass ratio 2: 1 is mixed;
The complex carrier is mixed by active carbon-bamboo fibre compound and DEXTROSE ANHYDROUS in mass ratio 1: 15, the work Property charcoal-bamboo fibre compound be active carbon and bamboo fibre active carbon in mass ratio: bamboo fibre=1: the mixtures of 3 compositions;
The fermented type Chinese herbal medicine extract powder prepares as follows:
S1, the preparation of clostridium butyricum RCM-2 fermentation seed liquid:
Using 9 step of embodiment (1) in number of patent application CN201710559482.8 ~ (2) the method, clostridium butyricum is made RCM-2 fermentation seed liquid;
S2, the preparation of mixed fermentation strain:
In terms of quality percent by volume g/mL, commercially available water-soluble enterococcus faecalis bacterium powder is thrown to clostridium butyricum according to 7% ratio In RCM-2 fermentation seed liquid, dissolution is mixed, and mixed fermentation strain is made;
S3, fermentation substrate preparation:
The dry material of radix pseudostellariae, cassia seed, Radix Astragali, radix scutellariae, white folder leaf of bamboo five tastes Chinese herbal medicine is crushed to 60 mesh respectively;Then with The sum of mass percentage is 100% meter, takes radix pseudostellariae 40%, cassia seed 20%, Radix Astragali 15%, radix scutellariae 15%, the white folder leaf of bamboo 10%, is mixed It closes uniformly, fermentation substrate is made;
S4, the preparation of radix pseudostellariae extract:
Using 1 the method for embodiment in number of patent application CN201610759126.6, radix pseudostellariae extract is made;
S5, radix pseudostellariae extract liquid fermentation:
The water that the radix pseudostellariae extract that S4 is obtained adds 1.5 mass times is diluted, with the hydrochloric acid of 1M and/or the hydroxide of 1M Sodium solution adjusts pH value to 6.0, then with volume percentage, by the mixed fermentation strain of S2 preparation according to 7% inoculative proportion Static fermentation is carried out in radix pseudostellariae extract after being inoculated in dilution, the fermentation termination time is 48 h;
S6, fermentation substrate solid state fermentation:
By percentage to the quality, the fermentation base of S3 preparation is added according to 30% ratio using the fermentation liquid of S5 preparation as seed liquor In matter, after mixing, direct packaging is in carrying out solid stationary fermentation in fermentation bag, fermentation temperature is 37 DEG C, fermentation time 2 Week;
S7, effective substance extract:
When S6 fermentation termination, fermentation bag is opened, the water of fermentation material plus 10 mass times is extracted, Extracting temperature 100 DEG C, extraction time be 4 h, extracting solution is carried out using three-level filter system described in number of patent application CN201610759126.6 Filtering, in terms of quality percent by volume g/mL, the auxiliary material glucose of directly addition 10% is spray-dried filtered liquid, Fermented type Chinese herbal medicine extract powder is made;
The active carbon-bamboo fibre compound prepares as follows:
Dry bamboo pole (picking up from Zherong County mountain planting bamboo grove, bamboo pole, that is, bamboo harvesting goes after branches and leaves to dry to be made) is used first Dicer is cut into the block of the equal 0.1cm of length and width, then crushes block, obtains bamboo fibre;According to quality specific activity Charcoal: bamboo fibre=1: 3 weigh two kinds of materials respectively, first account for the water of its mass percent 4% after the completion of weighing to bamboo fibre sprinkling, then Successively pass through Steam explosion treatment I and Steam explosion treatment II for double section Steam explosion treatments are carried out after two kinds of materials merging, Double sections of Steam explosion treatment interval times are 3min;Material after double sections of Steam explosion treatments is dried again, it is to be dried after again It crushes, the compound of active carbon and bamboo fibre is made after sieving with 100 mesh sieve;Wherein, the condition of Steam explosion treatment I are as follows: explosion chamber Coefficient is 0.8, and explosion steam pressure reaches 0.7MPa, and explosion pressure maintaining handles the time as 10min, and blasting time is not higher than 0.00875s;The condition of Steam explosion treatment II are as follows: blasting gear is quick-fried with cavity explosion treatment on the same stage with Steam explosion treatment I Broken steam pressure reaches 2.0MPa, and explosion pressure maintaining handles the time as 20s, and blasting time is not higher than 0.00875s.
A kind of preparation method for the pulvis taking off mould protect liver for livestock and poultry: hair is launched first into pulvis material mixing device Ferment type Chinese herbal medicine extract powder, compound probiotic bacterium powder, complex carrier are finally launched complex enzyme respectively again, multi-vitamins, are gone back Originality glutathione, is finally mixed, and the pulvis that mould protect liver is taken off for livestock and poultry is made;
The pulvis material mixing device as shown in Fig. 1 ~ 7, including rack, hybrid agent, control main body, negative pressure main body, take Sample main body, cleaning main body;
The rack includes the vertical support 2 that a horizontal base 1 and two are respectively and vertically fixed at 1 left and right ends of pedestal, bottom Seat 1 and 2 inner hollow of support;A back-up roller wheel bearing 3 is respectively fixedly connected on two opposite lateral walls of two supports 2;
The hybrid agent includes a V-type cylinder 4, which is docked by two cylindrical tubes, a cylindrical tube Top is equipped with feed inlet 5 and feed inlet capping 6, is respectively equipped with compatible collar extension 7(U type on feed inlet capping 6 and feed inlet 5) With latch closure 8(spiral rotating), seal washer 9 is additionally provided on feed inlet 5;The on both sides of the middle of V-type cylinder 4 is respectively fixedly connected with one turn Axis 10, two shafts 10 are respectively provided in the back-up roller wheel bearing 3 of respective side;The bottom of V-type cylinder 4 is equipped with discharge port 11, discharging Mouth 11 is equipped with valve 12;
The control main body includes motor 13,14, two infrared induction probes 16 of integrated control case, motor 13 and integrated control Case 14 is fixed at same 2 inside of support and the output end of motor 13 is connect with ipsilateral shaft 10, input terminal is controlled with integrated Case 14 processed is electrically connected, and the control panel of integrated control case 14 exposes to the outer surface of support 2, the power supply line 15 of integrated control case 14 It is drawn outside to support 2, two infrared induction probes 16 are respectively fixedly disposed at two supports 2 of 3 lower section of back-up roller wheel bearing On two opposite lateral walls;The control panel is equipped with power supply indicator 17, run indicator 18, start button 19, emergency stop Button 20, positive inching button 21, negative sense inching button 22, rotational speed governor 23, intelligent digital counter 24;Two infrared rays 16 parallel connection of inductive probe is electrically connected to intelligent digital counter 24;
The negative pressure main body includes the fixed blind flange 31 being located at the top of another cylindrical tube, is fixed on blind flange 31 true Sky pump 32, intelligent digital negative pressure controller 33, battery 34, the exhaust valve 35 for carrying charging jack, vacuum pump 32 and intelligent digital Negative pressure controller 33 is respectively electrically connected with battery 34, is connected between vacuum pump 32 and intelligent digital negative pressure controller 33 by signal wire It connects;Vacuum pump 32, intelligent digital negative pressure controller 33,35 bottom of exhaust valve respectively connect in a hollow tubing conductor 36 and V-type cylinder 4 Chamber communicates, and 36 bottom of hollow tubing conductor being connected with vacuum pump 32 is equipped with cooling gas check valve 37;The detachable company in 31 bottom of blind flange Connect a negative pressure protective cover 38, the bottom end of three hollow tubing conductors 36 and cooling gas check valve 37 are respectively positioned in negative pressure protective cover 38;Institute It states that 38 upper section of negative pressure protective cover is cylindrical, lower section is in back taper, has been evenly arranged several on back taper negative pressure protective cover 38 Stomata (pore opening 3mm), three layers of non-woven fabrics are fitted with outside back taper negative pressure protective cover 38, and non-woven fabrics passes through annulus 39 It is pressed on cylindrical negative pressure protective cover 38;Wherein, the detachable connection between blind flange 31 and negative pressure protective cover 38 is spiral shell Line connection, i.e. flange pan bottom are equipped with internal screw thread counterbore, cylindrical 38 top of negative pressure protective cover is equipped with external screw thread, cylindrical negative pressure In the internal screw thread of the external screw thread precession flange pan bottom counterbore of protective cover 38;
The sampling main body includes concave groove 25, the bottom wall fitting of concave groove 25 be fixed on the inner sidewall of V-type cylinder 4 and The lower end of concave groove 25 is abutted against with discharge port 11;V-type cylinder 4 is penetrated on the bottom wall of concave groove 25 is fixedly uniformly arranged with three Sample tap 26, three sample taps 26 are equally arranged along concave groove bottom wall direction, spacing size 15cm, bottom sample tap 26 Vertical height with discharge port 11 is 10cm;The sample tap 26 includes circular base 261, the outer silk 262 of clip, circular base 261 one end is fixed on 25 bottom wall of concave groove, the other end penetrates V-type cylinder 4 and extends outwardly and outside the end and clip The other end of the threaded threaded one end connection of silk 262, the outer silk 262 of clip has blocking film 263, circular base by clamp connection It is successively arranged ring washer 264 and diaphragm seal 265 from inside to outside between 261 and threaded one end of the outer silk 262 of clip;
The sampling main body further include with the matching used probe tube 27 of sample tap 26, the front end of probe tube 27 offers sample and enters Mouthfuls 271, rear end is screw thread handle 272, sample inlet 271 it is whole in flat but front end in pointed, from sample on probe tube 27 The rear end of entrance 271 opens up one section of gap gap 273(, 273 width for 1cm), at 273 rear of gap inside probe tube 27 backwards Position is equipped with the horizontal space between the gap circular baffle plate 274(273 compatible with probe tube 27 and circular baffle plate 274 4cm);
The cleaning main body includes two tubular inlets 28, and two inlets 28 are respectively provided at two cylindrical tube top sides On wall, the bottom end of two inlets 28 is respectively connected with rotary wash ball 29, the cylindrical tube inner wall of two 28 lower sections of inlet Upper detachable connection has closed protective cover 30, and the closed protective cover 30 is cylinder, the bottom end of two inlets 28 And rotary wash ball 29 is respectively positioned in closed protective cover 30;Wherein, between cylindrical tube and closed protective cover 30 can It is detachably connected with to be threadedly coupled, i.e., cylindrical tube inner wall is equipped with internal screw thread counterbore, 30 top of closed protective cover equipped with outer Screw thread, in the internal screw thread of the external screw thread precession cylindrical tube inner wall counterbore of closed protective cover 30.
The operational process of pulvis material mixing device are as follows: assigned first in livestock and poultry medicinal powder powder production instruction order laggard Row parameter setting, specifically includes: (1) carrying out rotary speed parameter setting by rotational speed governor 23;(2) pass through intelligent digital counter 24 carry out revolution parameter setting;(3) negative pressure pressure parameter setting in overall process is carried out by intelligent digital negative pressure controller 33;So Corresponding pulvis major ingredient and auxiliary material are entered into V-type cylinder by feed inlet 5 respectively according to the production requirement on production instruction order afterwards Body 4, then operator can leave scene after pressing start button 19, and power supply indicator 17, run indicator 18 are bright this moment;To When reaching 24 1 sections of parameter setting values of intelligent digital counter, V-type cylinder 4 is out of service, QA personnel first open clip remove it is stifled Piece 263, hand-held probe tube 27 are quickly sequentially inserted into three sample taps 26 and are sampled, chemical examination detection or three after sample equivalent merges Part chemically examines detection level respectively;Blocking film 263 is fastened with clip again after sampling, presses start button 19 again;It is to be achieved V-type cylinder 4 is out of service when 24 2 sections of parameter setting values of intelligent digital counter, first closes the switch of battery 34 and stops power supply, connects Opening exhaust valve 35, finally open valve 12 make preform by discharge port 11 releasing carry out the operation such as packing;When putting It is adjusted during material if there is low-angle, it can manual crawl forward direction inching button 21, the progress V-type cylinder of negative sense inching button 22 The fine position of body 4;If can directly press scram button when needing to terminate operation there are problem in mixing operating process 20;Cleaning operation can be carried out after material mixes end and blowing, blind flange 31 is changed to common flange first Disk (is not provided with vacuum pump 32, intelligent digital negative pressure controller 33, battery 34, the exhaust valve 35 for carrying charging jack) thereon, Back out closed protective cover 30;Valve 12 is opened again, external infusion pipeline is connected at discharge port 11, finally by feed liquor exterior line It is connected to the internal washing operation that two inlets 28 carry out V-type cylinder 4.
Furthermore it is also possible to carry out 4 leakproofness inspection operation of V-type cylinder: to (refer to and material is not added) before the mixing of each material Each component of V-type cylinder 4 is closed or fixed, vacuum pump 32 is then started, battery 34 is closed when setting value to be achieved and is opened It closes, then pressure stabilizing 5min, proves good airproof performance if 33 numerical value of intelligent digital negative pressure controller is constant, if numerical value increase indicates There are problems for leakproofness.
Reference examples 1
Difference from example 1 is that: prepare herbal raw material difference used when fermented type Chinese herbal medicine extract powder, step The specific steps of rapid S3 are as follows:
The dry material of Radix Astragali, radix scutellariae, Schisandra chinensis, four taste Chinese herbal medicine of radix bupleuri is crushed respectively;Then, in terms of mass percentage, Radix Astragali 40%, radix scutellariae 20%, Schisandra chinensis 20%, radix bupleuri 20% are taken, is uniformly mixed, fermentation substrate is made.
Other steps are the same as embodiment 1.
Clinical effectiveness
(1) test method
Respondent of 80 original body mass for the sow pig of 45kg or so as this research topic is selected, is divided at random Four groups, test site is Zherong County Fujian Bei Di pharmaceutcal corporation, Ltd test site, and test period is in May, 2018, test period 2 Week pig vaginal orifice area is measured respectively in 0,3,7,10,14d, 0d is the time of experiment the previous day.Wherein, the survey of vaginal orifice area Amount method is to measure vaginal orifice respectively in 0,3,7,10,14d respectively using vernier caliper based on sow vaginal orifice is considered as diamond shape character Length and width, by diamond shape reference area, formula are as follows: the measurement and calculating of length × wide/2(vaginal orifice, bibliography: Jiang Shuzhen Equal zearalenone pollution daily ration is to the influence zearalenone pollution daily ration of wean sow vaginal orifice to wean sow yin Animal and veterinary 2012, the Shandong influence (33) at family: 4-6), the sow vaginal orifice area of different times is calculated.And it is different The formula of the sow vaginal orifice area change rate of measurement point are as follows: sow vaginal orifice area change rate=(S1-S0)/S0* 100%, wherein S1 For the sow vaginal orifice area value of 0d, S1For the sow vaginal orifice area value of 3,7,10,14d.
It is grouped daily ration:
Control group 1: normal corn type diet is freely eaten, is used in conjunction 2 weeks;
Control group 2: mouldy corn type diet (ZEA200ppb) is freely eaten, is used in conjunction 2 weeks;
Control group 3: mouldy corn type diet (ZEA200ppb)+1 pulvis of reference examples (2kg/T) is freely eaten, is used in conjunction 2 weeks;
Processing group 1: mouldy corn type diet (ZEA200ppb)+1 pulvis of embodiment (2kg/T) is freely eaten, is used in conjunction 2 weeks;
" ZEA " among the above is the english abbreviation of zearalenone, and " ZEA200ppb " represents corn in mouldy corn type diet Zeranol content is 200ppb, and " 2kg/T " represents the reference examples 1 or embodiment powder of mouldy corn type diet addition 2kg per ton Agent;The group of normal corn type diet and mouldy corn type diet becomes (in terms of mass percentage): corn 65.1%, dregs of beans 26.4%, wheat bran 3.0%, fish meal 1.5%, premix 4.0%.
(2) test result
As shown in Table 1, the pulvis of mouldy corn type diet addition embodiment 1, can mitigate and alleviate significantly sow pig jade Zearlenone poisoning symptom.
Pig liver enzymatic activity index separately is detected in off-test, as shown in table 2.
As can be seen from Table 3,1 liver glutamic-pyruvic transaminase (GPT) of processing group, glutamic-oxalacetic transaminease (GOT), alkaline phosphatase (ALP) it is significantly improved than control group 1-3 with glutathione S-transferase (GST) activity, illustrates pulvis pair of the invention Animal's liver can play the role of protection.

Claims (10)

1. a kind of pulvis for taking off mould protect liver for livestock and poultry, which is characterized in that by the sum of mass percentage be 100% in terms of, by following Each raw material of mass percentage is made: fermented type Chinese herbal medicine extract powder 15 ~ 20%, complex enzyme 5 ~ 10%, multi-vitamins 5 ~ 10%, reductive glutathione 1 ~ 5%, compound probiotic bacterium powder 5 ~ 10%, surplus are complex carrier;
The complex enzyme is by glucose oxidase and protease (2 ~ 5) in mass ratio: 1 mixes;
The multi-vitamins are by vitamin C, vitamin A and vitamin E (1 ~ 5) in mass ratio: (1 ~ 3): (1 ~ 2) mixing and At;
The compound probiotic bacterium powder is by taking off mould class probiotics and the health-related probiotics of enteron aisle (1 ~ 5) in mass ratio: 1 mixing and At, it is described that take off mould class probiotics be commercially available bacillus subtilis, the health-related probiotics of enteron aisle by commercial plant lactobacillus and Enterococcus faecalis BD-1 (1 ~ 3) in mass ratio: 1 mixes;
The complex carrier is by active carbon-bamboo fibre compound and DEXTROSE ANHYDROUS in mass ratio 1: (5 ~ 20) mix, institute Stating active carbon-bamboo fibre compound is active carbon and bamboo fibre active carbon in mass ratio: bamboo fibre=1: the mixing of (1 ~ 5) composition Object;
The fermented type Chinese herbal medicine extract powder prepares as follows:
S1, the preparation of clostridium butyricum RCM-2 fermentation seed liquid:
Using method described in number of patent application CN201710559482.8, clostridium butyricum RCM-2 fermentation seed liquid is made;
S2, the preparation of mixed fermentation strain:
In terms of quality percent by volume g/mL, commercially available water-soluble enterococcus faecalis bacterium powder is thrown to butyric acid according to 5 ~ 10% ratio In clostridium RCM-2 fermentation seed liquid, dissolution is mixed, and mixed fermentation strain is made;
S3, fermentation substrate preparation:
The dry material of radix pseudostellariae, cassia seed, Radix Astragali, radix scutellariae, white folder leaf of bamboo five tastes Chinese herbal medicine is crushed respectively;Then with quality hundred Divide the sum of content for 100% meter, takes radix pseudostellariae 30 ~ 45%, cassia seed 15 ~ 30%, Radix Astragali 15 ~ 25%, radix scutellariae 15 ~ 20%, the white folder leaf of bamboo 10 ~ 15%, it is uniformly mixed, fermentation substrate is made;
S4, the preparation of radix pseudostellariae extract:
Using method described in number of patent application CN201610759126.6, radix pseudostellariae extract is made;
S5, radix pseudostellariae extract liquid fermentation:
The water that the radix pseudostellariae extract that S4 is obtained adds 1 ~ 1.5 mass times is diluted, adjusting pH value to 6.0 ~ 6.5, then With volume percentage, the mixed fermentation strain of S2 preparation is inoculated in the radix pseudostellariae after dilution according to 3 ~ 7% inoculative proportion and is extracted It takes and carries out static fermentation in object, the fermentation termination time is 40 ~ 48 h;
S6, fermentation substrate solid state fermentation:
By percentage to the quality, the fermentation of S3 preparation is added according to 30 ~ 40% ratio using the fermentation liquid of S5 preparation as seed liquor In matrix, after mixing, direct packaging is in progress solid stationary fermentation in fermentation bag, when fermentation temperature is 30 ~ 37 DEG C, ferments Between be 1 ~ 2 week;
S7, effective substance extract:
When S6 fermentation termination, fermentation bag to be opened, the water of fermentation material plus 10 ~ 15 mass times is extracted, Extracting temperature is 90 ~ 100 DEG C, extraction time be 3 ~ 5 h, extracting solution is using three-stage filtration system described in number of patent application CN201610759126.6 System is filtered, filtered liquid in terms of quality percent by volume g/mL, directly addition account for its 5 ~ 10% auxiliary material glucose into Row spray drying, is made fermented type Chinese herbal medicine extract powder.
2. the pulvis of mould protect liver is taken off for livestock and poultry as described in claim 1, it is characterised in that: the enzyme activity of glucose oxidase 8000 ~ 10000 U/g, the enzyme activity of protease are 50000 ~ 100000 U/g;The potency of vitamin A is 500000-1000000 IU/g, the potency of vitamin E are 500 ~ 1000 IU/g;Viable count >=1.0 × 10 of commercially available bacillus subtilis8CFU/g, city Sell viable count >=1.0 × 10 of lactobacillus plantarum8CFU/g, viable count >=1.0 × 10 of enterococcus faecalis BD-18CFU/g, commercially available water Viable count >=1.0 × 10 of dissolubility enterococcus faecalis bacterium powder8CFU/g。
3. the pulvis of mould protect liver is taken off for livestock and poultry as described in claim 1, it is characterised in that: the active carbon-bamboo fibre is multiple Object is closed to prepare as follows:
Dry bamboo pole is cut into the block of the equal 0.1 ~ 1cm of length and width first, then crushes block, it is fine to obtain bamboo Dimension;
According to quality than active carbon: bamboo fibre=1: (1 ~ 5) weighs two kinds of materials respectively, first sprays to bamboo fibre after the completion of weighing The water of its mass percent 3 ~ 5% is accounted for, then it is successively quick-fried by steam that double section Steam explosion treatments are carried out after two kinds of materials are merged Tear manages I and Steam explosion treatment II, and double sections of Steam explosion treatment interval times are 2 ~ 5min;After double sections of Steam explosion treatments Material is dried again, is crushed again after to be dried, and active carbon-bamboo fibre compound is made after crossing 80 ~ 100 meshes;
Wherein, the condition of Steam explosion treatment I are as follows: explosion chamber coefficient is 0.8 ~ 0.9, explosion steam pressure up to 0.6 ~ 0.8MPa, explosion pressure maintaining handle the time as 5 ~ 10min, and blasting time is not higher than 0.00875s;The condition of Steam explosion treatment II Are as follows: blasting gear with cavity explosion treatment, protect up to 1.5 ~ 2.5MPa, explosion by explosion steam pressure on the same stage with Steam explosion treatment I The pressure processing time is 10 ~ 30s, and blasting time is not higher than 0.00875s.
4. a kind of preparation method of the pulvis for taking off mould protect liver for livestock and poultry as described in claim 1 ~ 3 is any, it is characterised in that: Fermented type Chinese herbal medicine extract powder, compound probiotic bacterium powder, complex carrier are launched first into pulvis material mixing device, most It launches complex enzyme, multi-vitamins, reductive glutathione respectively again afterwards, is finally mixed, be made and take off mould shield for livestock and poultry The pulvis of liver.
5. the preparation method of the pulvis of mould protect liver is taken off for livestock and poultry as claimed in claim 4, it is characterised in that: the pulvis Material mixing device includes rack, hybrid agent, control main body, negative pressure main body;
The rack includes the vertical support that a horizontal base and two are respectively and vertically fixed at pedestal left and right ends, pedestal and Support inner hollow;A back-up roller wheel bearing is respectively fixedly connected on two opposite lateral walls of two supports;
The hybrid agent includes a V-type cylinder, which is docked by two cylindrical tubes, a cylindrical tube top Portion is equipped with feed inlet and feed inlet covers, and is respectively equipped with compatible collar extension and latch closure on feed inlet capping and feed inlet;V-type cylinder The on both sides of the middle of body is respectively fixedly connected with a shaft, and two shafts are respectively provided in the back-up roller wheel bearing of respective side;V-type cylinder Bottom is equipped with discharge port, and discharge port is equipped with valve;
The control main body includes motor, integrated control case, two infrared induction probes, and motor and the fixation of integrated control cabinet are set It sets inside same support and the output end of motor is connect with ipsilateral shaft, input terminal is electrically connected with integrated control case, integrate The control panel of control cabinet exposes to the outer surface of support, and the power supply line of integrated control case is drawn to carrier exterior, two infrared Line inductive probe is respectively fixedly disposed on two opposite lateral walls of two supports below back-up roller wheel bearing;The control panel It is equipped with power supply indicator, run indicator, start button, scram button, positive inching button, negative sense inching button, revolving speed Controller, intelligent digital counter;Two infrared induction probe parallel connections are electrically connected to intelligent digital counter;
The negative pressure main body includes the fixed blind flange being located at the top of another cylindrical tube, is fixed with vacuum on blind flange Pump, intelligent digital negative pressure controller, battery, the exhaust valve for carrying charging jack, vacuum pump and intelligent digital negative pressure controller are each It is electrically connected from battery, is connected between vacuum pump and intelligent digital negative pressure controller by signal wire;Vacuum pump, intelligent digital are negative Pressure controller, exhaust valve bottom respectively connect a hollow tubing conductor and communicate with V-type cylinder lumen, the hollow tubing conductor being connected with vacuum pump Bottom is equipped with cooling gas check valve;One negative pressure protective cover of blind flange bottom detachable connection, the bottom end of three hollow tubing conductors and Cooling gas check valve is respectively positioned in negative pressure protective cover;The negative pressure protective cover upper section is cylindrical, lower section is in back taper, and back taper is negative Several stomatas have been evenly arranged on pressure protective cover, have been fitted with several layers non-woven fabrics, nonwoven outside back taper negative pressure protective cover Cloth is pressed on cylindrical negative pressure protective cover by annulus.
6. the preparation method of the pulvis of mould protect liver is taken off for livestock and poultry as claimed in claim 5, it is characterised in that: blind flange and negative Pressing the detachable connection between protective cover is to be threadedly coupled, i.e., flange pan bottom is equipped with internal screw thread counterbore, cylindrical negative pressure is protected Shield top is equipped with external screw thread, in the internal screw thread of the external screw thread precession flange pan bottom counterbore of cylindrical negative pressure protective cover;Stomata Size is 1 ~ 5mm, and the number of plies of non-woven fabrics is 1 ~ 5 layer.
7. the preparation method of the pulvis of mould protect liver is taken off for livestock and poultry as claimed in claim 5, it is characterised in that: the pulvis Material mixing device further includes sampling main body and/or cleaning main body;
The sampling main body includes concave groove, and the bottom wall fitting of concave groove is fixed on the inner sidewall of V-type cylinder and concave The lower end of slot is abutted against with discharge port;V-type cylinder is penetrated on the bottom wall of concave groove is fixedly uniformly arranged with several sample taps;Institute Stating sample tap includes circular base, the outer silk of clip, and one end of circular base is fixed in concave groove bottom wall, the other end penetrates V-type cylinder extends outwardly and the end is connect with the threaded threaded one end of the outer silk of clip, and the other end of the outer silk of clip passes through card Hoop is connected with blocking film;
The cleaning main body includes two tubular inlets, and two inlets are respectively provided at two cylindrical tube top sidewalls On, the bottom end of two inlets is respectively connected with rotary wash ball, detachable on the cylindrical tube inner wall below two inlets Formula is connected with closed protective cover, and the closed protective cover is cylinder, the bottom end of two inlets and rotary wash ball It is respectively positioned in closed protective cover.
8. as claimed in claim 7 for livestock and poultry take off mould protect liver pulvis preparation method, it is characterised in that: circular base with It is successively arranged ring washer and diaphragm seal from inside to outside between threaded one end of the outer silk of clip;Cylindrical tube and closed protection Detachable connection between cover is to be threadedly coupled, i.e., cylindrical tube inner wall is equipped with internal screw thread counterbore, closed protective cover top It holds and is equipped with external screw thread, in the internal screw thread of the external screw thread precession cylindrical tube inner wall counterbore of closed protective cover;Several sample taps Equally it is arranged along concave groove bottom wall direction, 5 ~ 15 cm of spacing size, the vertical height of bottom sample tap and discharge port is 10~20 cm。
9. the preparation method of the pulvis of mould protect liver is taken off for livestock and poultry as claimed in claim 7, it is characterised in that: the sampling master Body further include with the matching used probe tube of sample tap, the front end of probe tube offer sample inlet, rear end be screw thread handle, sample Product entrance is integrally in flat but front end in pointed, opens up one section of gap backwards from the rear end of sample inlet on probe tube, samples Circular baffle plate compatible with probe tube is equipped in gap rear position inside pipe.
10. the preparation method of the pulvis of mould protect liver is taken off for livestock and poultry as claimed in claim 9, it is characterised in that: gap width For 5mm ~ 2cm, the horizontal space between gap and circular baffle plate is 3 ~ 6 cm.
CN201811153351.0A 2018-09-30 2018-09-30 A kind of pulvis and preparation method thereof taking off mould protect liver for livestock and poultry Pending CN108935962A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201811153351.0A CN108935962A (en) 2018-09-30 2018-09-30 A kind of pulvis and preparation method thereof taking off mould protect liver for livestock and poultry

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201811153351.0A CN108935962A (en) 2018-09-30 2018-09-30 A kind of pulvis and preparation method thereof taking off mould protect liver for livestock and poultry

Publications (1)

Publication Number Publication Date
CN108935962A true CN108935962A (en) 2018-12-07

Family

ID=64471324

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201811153351.0A Pending CN108935962A (en) 2018-09-30 2018-09-30 A kind of pulvis and preparation method thereof taking off mould protect liver for livestock and poultry

Country Status (1)

Country Link
CN (1) CN108935962A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110787204A (en) * 2019-12-16 2020-02-14 福建贝迪药业有限公司 Fermented radix pseudostellariae liquid feed microecological preparation and preparation method thereof
CN110982868A (en) * 2019-11-29 2020-04-10 贵州中医药大学 Co-culture method for improving triterpene content of ganoderma lucidum and application
CN111802513A (en) * 2019-04-11 2020-10-23 河北维尔利动物药业集团有限公司 Preparation method of glucose oxidase probiotic additive for poultry livestock feed
CN114794324A (en) * 2022-05-06 2022-07-29 安徽喜乐佳生物科技有限公司 Pregnant sow feed

Citations (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102232998A (en) * 2011-04-15 2011-11-09 北京康华远景科技有限公司 Micro-ecological traditional Chinese medicine preparation for enhancing immunity of livestock and poultry, and preparation method thereof
CN202876725U (en) * 2012-10-30 2013-04-17 湖北博大高科生物技术有限公司 V-shaped mixer
CN103535524A (en) * 2013-09-30 2014-01-29 宝鸡市星星协力生物有限公司 Compound type disinfecting mold-removal additive for feed
CN104381687A (en) * 2014-11-24 2015-03-04 柳州华晟科技有限公司 Pig feed additive
CN105594994A (en) * 2015-12-30 2016-05-25 浙江大飞龙动物保健品有限公司 Mildew-proof detoxication and detoxification mixed type feed additive
CN105724772A (en) * 2016-02-24 2016-07-06 济南亿民动物药业有限公司 Chinese herbal medicine micro-ecological compound feed additive and preparation and use method thereof
CN205461858U (en) * 2016-02-02 2016-08-17 福建贝迪药业有限公司 Automatic material mixing equipment of mixed type feed additive
CN205473763U (en) * 2016-01-20 2016-08-17 福建贝迪药业有限公司 Micro -ecological agents sampler
CN106036040A (en) * 2016-07-31 2016-10-26 镇江天和生物技术有限公司 Mixed feed additive
CN106064034A (en) * 2016-07-04 2016-11-02 苏州北开生化设备有限公司 A kind of self controllable vacuum V-Mixer and using method thereof
CN106176882A (en) * 2016-08-30 2016-12-07 福建贝迪药业有限公司 A kind of preparation method of Radix Pseudostellariae extract
CN106214725A (en) * 2016-08-30 2016-12-14 福建贝迪药业有限公司 A kind of preparation method of Radix Pseudostellariae palpus extract
CN106306358A (en) * 2016-07-20 2017-01-11 洛阳欧科拜克生物技术股份有限公司 Formula and production technology of fermentation traditional Chinese medicine feed additive
CN205988709U (en) * 2016-07-01 2017-03-01 常州恒干干燥设备有限公司 Automatically cleaning mixer
CN107118997A (en) * 2017-07-11 2017-09-01 福建贝迪药业有限公司 A kind of feeding clostridium butyricum, the probiotics for promoting growth of animals or poultry and preparation method thereof
CN107254424A (en) * 2017-07-11 2017-10-17 福建贝迪药业有限公司 A kind of livestock and poultry new liquid compound micro-ecological preparation and preparation method thereof
CN107312730A (en) * 2017-07-11 2017-11-03 福建贝迪药业有限公司 A kind of compound Chinese herb probiotics and its Quick production method based on solid state fermentation
CN107338203A (en) * 2017-07-11 2017-11-10 福建贝迪药业有限公司 A kind of feeding enterococcus faecalis, the probiotics for preventing and treating fowl and animal thermal stress and preparation method thereof
CN108094681A (en) * 2018-01-04 2018-06-01 商丘塞弗顿生物工程有限公司 A kind of de- mould feed addictive and preparation method thereof that detoxifies

Patent Citations (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102232998A (en) * 2011-04-15 2011-11-09 北京康华远景科技有限公司 Micro-ecological traditional Chinese medicine preparation for enhancing immunity of livestock and poultry, and preparation method thereof
CN202876725U (en) * 2012-10-30 2013-04-17 湖北博大高科生物技术有限公司 V-shaped mixer
CN103535524A (en) * 2013-09-30 2014-01-29 宝鸡市星星协力生物有限公司 Compound type disinfecting mold-removal additive for feed
CN104381687A (en) * 2014-11-24 2015-03-04 柳州华晟科技有限公司 Pig feed additive
CN105594994A (en) * 2015-12-30 2016-05-25 浙江大飞龙动物保健品有限公司 Mildew-proof detoxication and detoxification mixed type feed additive
CN205473763U (en) * 2016-01-20 2016-08-17 福建贝迪药业有限公司 Micro -ecological agents sampler
CN205461858U (en) * 2016-02-02 2016-08-17 福建贝迪药业有限公司 Automatic material mixing equipment of mixed type feed additive
CN105724772A (en) * 2016-02-24 2016-07-06 济南亿民动物药业有限公司 Chinese herbal medicine micro-ecological compound feed additive and preparation and use method thereof
CN205988709U (en) * 2016-07-01 2017-03-01 常州恒干干燥设备有限公司 Automatically cleaning mixer
CN106064034A (en) * 2016-07-04 2016-11-02 苏州北开生化设备有限公司 A kind of self controllable vacuum V-Mixer and using method thereof
CN106306358A (en) * 2016-07-20 2017-01-11 洛阳欧科拜克生物技术股份有限公司 Formula and production technology of fermentation traditional Chinese medicine feed additive
CN106036040A (en) * 2016-07-31 2016-10-26 镇江天和生物技术有限公司 Mixed feed additive
CN106214725A (en) * 2016-08-30 2016-12-14 福建贝迪药业有限公司 A kind of preparation method of Radix Pseudostellariae palpus extract
CN106176882A (en) * 2016-08-30 2016-12-07 福建贝迪药业有限公司 A kind of preparation method of Radix Pseudostellariae extract
CN107118997A (en) * 2017-07-11 2017-09-01 福建贝迪药业有限公司 A kind of feeding clostridium butyricum, the probiotics for promoting growth of animals or poultry and preparation method thereof
CN107254424A (en) * 2017-07-11 2017-10-17 福建贝迪药业有限公司 A kind of livestock and poultry new liquid compound micro-ecological preparation and preparation method thereof
CN107312730A (en) * 2017-07-11 2017-11-03 福建贝迪药业有限公司 A kind of compound Chinese herb probiotics and its Quick production method based on solid state fermentation
CN107338203A (en) * 2017-07-11 2017-11-10 福建贝迪药业有限公司 A kind of feeding enterococcus faecalis, the probiotics for preventing and treating fowl and animal thermal stress and preparation method thereof
CN108094681A (en) * 2018-01-04 2018-06-01 商丘塞弗顿生物工程有限公司 A kind of de- mould feed addictive and preparation method thereof that detoxifies

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111802513A (en) * 2019-04-11 2020-10-23 河北维尔利动物药业集团有限公司 Preparation method of glucose oxidase probiotic additive for poultry livestock feed
CN110982868A (en) * 2019-11-29 2020-04-10 贵州中医药大学 Co-culture method for improving triterpene content of ganoderma lucidum and application
CN110982868B (en) * 2019-11-29 2023-09-19 贵州中医药大学 Co-culture method for improving triterpene content of ganoderma lucidum and application thereof
CN110787204A (en) * 2019-12-16 2020-02-14 福建贝迪药业有限公司 Fermented radix pseudostellariae liquid feed microecological preparation and preparation method thereof
CN114794324A (en) * 2022-05-06 2022-07-29 安徽喜乐佳生物科技有限公司 Pregnant sow feed

Similar Documents

Publication Publication Date Title
CN108935962A (en) A kind of pulvis and preparation method thereof taking off mould protect liver for livestock and poultry
JP3677656B2 (en) Feed additive for increasing physiological activity and promoting growth and growth of cultured marine fish using effective microorganisms and herbal medicines and method for producing the same
CN106173613A (en) A kind of probiotics fermention is utilized to prepare fruit and vegerable or corn or the method for integration of edible and medicinal herbs ferment health food
CN105535387B (en) Animal and bird intestines diarrhea ferment and preparation method thereof can be improved
CN110037166A (en) A kind of preparation method of Procambius clarkii Chinese herbal medicine composite fermented feed
CN110200154A (en) Pig starter feed of the yeast culture containing antibacterial type and its preparation method and application
CN106071051A (en) A kind of for complex microorganism additive removing mycotoxin and preparation method thereof
CN115678781B (en) Microbial inoculum for animal culture fermentation bed and preparation method thereof
CN107927449A (en) The preparation method of microbial fermentation prawn feed
CN113080324A (en) Pig feed additive and production method thereof
CN108813107A (en) Peanut shell powder biological fermentation feed and preparation method thereof
CN105994937A (en) Green organic selenium-rich feed and preparation method thereof
CN110973349A (en) Anti-diarrhea fermented Chinese herbal medicine feed additive for livestock and poultry and preparation method thereof
CN117070427B (en) Lactobacillus buchneri and silage starter thereof
CN113151032A (en) Bacillus subtilis with efficient gossypol degradation capability and application thereof
CN104839426B (en) A kind of biological fermentation feed and preparation method thereof
CN107586727B (en) Fermentation method of ganoderma lucidum mycelia
CN106579094A (en) Medicago sativa fine powder production process
Bhat et al. Human and animal health significance of mycotoxins in sorghum with special reference to fumonisins
CN106616001A (en) Novel tilapia feed produced from cassava lees through microbial fermentation and preparation method of tilapia feed
CN109527201A (en) A kind of channel catfishes fermentation expanded pellet diet and preparation method thereof to purify water
CN115624579A (en) Traditional Chinese medicine composition for inhibiting aeromonas veronii and application thereof
CN108795829A (en) Bacillus subtilis and its application in microbial inoculum and pork pig feed
CN110150457A (en) A kind of antibacterial type yeast culture and its application
CN104905064B (en) Indian meal moth man-made feeds and preparation method thereof

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20181207