CN103535524A - Compound type disinfecting mold-removal additive for feed - Google Patents
Compound type disinfecting mold-removal additive for feed Download PDFInfo
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- CN103535524A CN103535524A CN201310468893.8A CN201310468893A CN103535524A CN 103535524 A CN103535524 A CN 103535524A CN 201310468893 A CN201310468893 A CN 201310468893A CN 103535524 A CN103535524 A CN 103535524A
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Abstract
The invention provides a compound type disinfecting mold-removal additive for feed which comprises the following raw materials in parts by weight: 20-25 parts of nanometer montmorillonite powder, 40-50 parts of compound feeding microecological preparation, 10-20 parts of complex enzyme preparation, 2-3 parts of honeysuckle extract, 2-3 parts of fructus forsythiae extract, 3-5 parts of indigowoad root extract and 3-5 parts of vitamin C, and the compound type disinfecting mold-removal additive is prepared by mixing the raw materials uniformly. Through repeated animal experiments, the compound type disinfecting mold-removal additive has the effects of removing toxins generated by autophage of animals and exogenous mycotoxin infected in the case that animals eat mildewed feed and forage grass, enhancing the immunity of animal organism, reducing the death and culling rate, promoting the quality of animal food, and protecting the food safety.
Description
Technical field
The invention belongs to field of feed additive technology, be specifically related to the mould additive of compound detoxicating solution for a kind of feed, utilize the collaborative mycotoxin of removing in feed of bioanalysis and Physical, reduce the harm that mycotoxin is produced growth of animal, improve culture benefit.
Background technology
Along with the fast development of aquaculture to scale, standardization direction; the Raw material processing complete feeds such as a large amount of use corn of people, dregs of beans, wheat bran are to provide the nutrition (complete feed is exactly full-time grain mixed feed) of livestock and poultry abundance; but in these agricultural byproducts, generally contain various mycotoxins; particularly particularly outstanding in complete feed, the recall rate of mycotoxin is more than 90%.Mycotoxin is to produce the secondary metabolite producing in the process of malicious mould when field growing stage of cereal, results and storage or at feed, the most common and harm the most serious having: aflatoxin, conspicuous aspertoxin, vomitoxin, zearalenone etc.Animal edible going mouldy after feed of being destroyed of nutritional labeling, can cause acute and chronic poisoning, the adverse consequences such as immunity reduces, disease increases, the speed of growth slows down, severe patient livestock and poultry occur dead.And more seriously mould and the harmful metabolite thereof in feed, can be residual in liver, kidney, muscle, blood, milk and the egg of animal, cause the pollution of animal food, mycotoxin has strong carcinogenicity, by this food chain, the mankind's health is had to great potential hazard, and mycotoxin contamination has become global animal and fowl fodder and human food's safety deterrent at all times.At present, for the feed ，Yong Ministry of Agriculture of having gone mouldy, allow the mould inhibitor of interpolation to carry out mildew-resistant processing and can only go mould removing toxic substances, the main method of using has physical absorption, mixed diluting, chemical degradation etc., but these methods are cured the symptoms, not the disease and effect is not remarkable, be therefore necessary to improve.
Summary of the invention
The technical problem that the present invention solves: the mould additive of compound detoxicating solution for a kind of feed is provided, effectively control and solve/remove the pollution of mycotoxin to grain and feed, thereby improve pollution and infringement that animal body is produced, indirectly improve human food's safety.
The technical solution used in the present invention: the mould additive of compound detoxicating solution for a kind of feed, is comprised of the raw material of following weight parts:
With the mould additive of compound detoxicating solution, preferred following proposal:
Further, described compound feeding micro-ecological preparation is mixed by bacillus subtilis, bacillus licheniformis and lactic acid bacteria, and the mass ratio of bacillus subtilis, bacillus licheniformis and lactic acid bacteria is 5:3:1.
Further, described complex enzyme formulation is mixed by muramidase and glucose oxidase, and the mass ratio of muramidase and glucose oxidase is 2:1.
The present invention is through zoopery repeatedly; have and remove in animal body the toxin that self metabolism produces and the external source mycotoxin that feed and herbage infects that goes mouldy of searching for food, strengthen animal body immunity, reduce death rate; promote animal foodstuff quality, the effect of protection food security.
The specific embodiment
The first embodiment of the present invention is described below.(for routine prevention)
The mould additive of compound detoxicating solution for a kind of feed, get 20 kilograms, nano montmorillonite powder, (compound feeding micro-ecological preparation is mixed by bacillus subtilis, bacillus licheniformis and lactic acid bacteria for 40 kilograms of compound feeding micro-ecological preparations, wherein, bacillus subtilis (viable bacteria content is 2,000,000,000 CFU/ gram), bacillus licheniformis (viable bacteria content is 1,500,000,000 CFU/ gram), lactic acid bacteria (viable bacteria content is 1,000,000,000 CFU/ gram), and the mass ratio of bacillus subtilis, bacillus licheniformis and lactic acid bacteria is 5:3:1.), (complex enzyme formulation is mixed by muramidase and glucose oxidase, and the mass ratio of muramidase and glucose oxidase is 2:1 for 10 kilograms of complex enzyme formulations.), 2 kilograms of Honegsukle flower P.Es, 2 kilograms of forsythia suspense extractions, 3 kilograms of 3 kilograms of isatis root extracts and vitamin Cs mix and stir makes 80 kilograms of additives, then in 2 ‰ ratios, adds in complete feed, and mixing and stirring gets final product feeding animals.
The concrete mechanism of action of each component in the present embodiment is as follows:
1, nano montmorillonite:
(1) take off mould effect, nano montmorillonite has huge specific area, the mycotoxins such as aflatoxin are had to the superpower suction-operated of specificity, also there is mildew-resistant and mineral nutrition effect simultaneously, to the adsorption rate of mycotoxin, be wherein: aflatoxin 100%, zearalenone 80%, ochratoxin 70%, ergotoxin 85%
(2) good styptic, relieving diarrhea with astringents agent.
2, compound feeding micro-ecological preparation
Component: withered grass gemma: lichens gemma: lactic acid bacteria :=5:3:1(mass ratio)
Concrete effect: help animal to remove oxygen radical, in and Escherichia coli exotoxin, suppress intrinsic spoilage organisms in intestines, reduce the content of intestinal endotoxin and spoilage product, alleviate the removing toxic substances burden of animal's liver, strengthen the Nutrition and Metabolism function of liver.
3, complex enzyme formulation
Component: muramidase: glucose oxidase=2:1(mass ratio)
Concrete effect: the integrality of mycotoxin heavy damage intestinal epithelial cell.The prothetic group flavin adenine dinucleotide (FAD) of glucose oxidase can catalytic specie in cellular respiration metabolism redox reaction; there is multiple physiological effect; can remove free radical; the intestinal epithelial cell that watches for animals is complete; remove the destruction of mycotoxin, thereby played the effect that resists mould and removing toxic substances.Muramidase can make Escherichia coli in animal intestinal reduce, and promotes the propagation of endogenous beneficial bacterium, and the infringement of emulative minimizing mould to intestinal mucosa, also can promote digesting and assimilating of protein in addition, improves the digestibility of feed.
4, vitamin C: function of detoxification, improves immunity.
5, Honegsukle flower P.E: clearing heat and detoxicating, anti-inflammatory.
6, forsythia suspense extraction: broad-spectrum antiseptic.
7, isatis root extract: antiviral.
The second embodiment of the present invention is described below.(while causing Animal diseases for mycotoxin)
The mould additive of compound detoxicating solution for a kind of feed, get 25 kilograms, nano montmorillonite powder, (compound feeding micro-ecological preparation is mixed by bacillus subtilis, bacillus licheniformis and lactic acid bacteria for 50 kilograms of compound feeding micro-ecological preparations, wherein, bacillus subtilis (viable bacteria content is 2,000,000,000 CFU/ gram), bacillus licheniformis (viable bacteria content is 1,500,000,000 CFU/ gram), lactic acid bacteria (viable bacteria content is 1,000,000,000 CFU/ gram), and the mass ratio of bacillus subtilis, bacillus licheniformis and lactic acid bacteria is 5:3:1.), (complex enzyme formulation is mixed by muramidase and glucose oxidase, and the mass ratio of muramidase and glucose oxidase is 2:1 for 20 kilograms of complex enzyme formulations.), 3 kilograms of Honegsukle flower P.Es, 3 kilograms of forsythia suspense extractions, 5 kilograms of 5 kilograms of isatis root extracts and vitamin Cs mix and stir makes 111 kilograms of additives, then in 1 ‰ ratios, adds in complete feed, and mixing and stirring gets final product feeding animals.
In above-described embodiment, the concrete mechanism of action of each component is with embodiment mono-.
The third embodiment of the present invention is described below.(addition when removing toxin)
The mould additive of compound detoxicating solution for a kind of feed, get 22 kilograms, nano montmorillonite powder, (compound feeding micro-ecological preparation is mixed by bacillus subtilis, bacillus licheniformis and lactic acid bacteria for 45 kilograms of compound feeding micro-ecological preparations, wherein, bacillus subtilis (viable bacteria content is 2,000,000,000 CFU/ gram), bacillus licheniformis (viable bacteria content is 1,500,000,000 CFU/ gram), lactic acid bacteria (viable bacteria content is 1,000,000,000 CFU/ gram), and the mass ratio of bacillus subtilis, bacillus licheniformis and lactic acid bacteria is 5:3:1.), (complex enzyme formulation is mixed by muramidase and glucose oxidase, and the mass ratio of muramidase and glucose oxidase is 2:1 for 15 kilograms of complex enzyme formulations.), 2.5 kilograms of Honegsukle flower P.Es, 2.5 kilograms of forsythia suspense extractions, 4 kilograms of 4 kilograms of isatis root extracts and vitamin Cs mix and stir makes 95 kilograms of additives, then in 1.5 ‰ ratios, adds in complete feed, and mixing and stirring gets final product feeding animals.
In above-described embodiment, the concrete mechanism of action of each component is with embodiment mono-.
With the additive that the present invention produces, carry out detoxification experiment, choose 20 farrowing sows and be divided at random two groups, with the feed slightly going mouldy, feed, control group Direct-fed, experimental group is added the additive of the present embodiment in 2/1000ths ratio, feed after 20 days, and experimental group sow upgrowth situation is good, hair color light, miscarriage and stillborn foetus do not occur, in control group sow growth bad, anorexia, hair color are dark and gloomy, heating paresthesia, has 2 miscarriages.
The present invention is also to there being the pig of various ill symptomses, and as feed intake reduces, weightening finish declines, growth retardation, liver tissue injury, the pig of the symptoms such as acute pulmonary edema, feed and added the feed of additive of the present invention, all received speed of weight increment raising, the effect that death rate reduces.
The present invention is as a kind of feed addictive; 1 ‰-2 ‰ add in animal perfect compound feed by mass percentage; can prevent feed mold; mould fungus inhibition growth; thereby eliminate the impact of mycotoxin on growth of animal, improve animal immunizing power, reduce death rate; protection food security, improves culture benefit.
Above-described embodiment, is preferred embodiment of the present invention, is not used for limiting the scope of the present invention, and the equivalence of being done with content described in the claims in the present invention therefore all changes, within all should being included in the claims in the present invention scope.
Claims (4)
1. the mould additive of compound detoxicating solution for feed, is characterized in that being comprised of the raw material of following weight parts:
2. the mould additive of compound detoxicating solution for feed according to claim 1, is characterized in that being comprised of the raw material of following weight parts:
3. the mould additive of compound detoxicating solution for feed according to claim 1 and 2, it is characterized in that: described compound feeding micro-ecological preparation is mixed by bacillus subtilis, bacillus licheniformis and lactic acid bacteria, and the mass ratio 5:3:1 of bacillus subtilis, bacillus licheniformis and lactic acid bacteria.
4. the mould additive of compound detoxicating solution for feed according to claim 1, it is characterized in that: described complex enzyme formulation is mixed by muramidase and glucose oxidase, and the mass ratio of muramidase and glucose oxidase is 2:1.
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Cited By (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103859165A (en) * | 2014-03-06 | 2014-06-18 | 苏州万生源生物科技有限公司 | Mycotoxin purification agent for feed and preparation method and application of agent |
| CN104872399A (en) * | 2014-02-28 | 2015-09-02 | 雨润慕德生物科技（连云港）有限公司 | Interferon livestock and poultry micro-ecology additive |
| CN105010801A (en) * | 2015-06-17 | 2015-11-04 | 盐城恒兴饲料有限公司 | Low fishmeal feed for final grow-out period of carassius auratus gibelio and preparation method thereof |
| CN105594994A (en) * | 2015-12-30 | 2016-05-25 | 浙江大飞龙动物保健品有限公司 | Mildew-proof detoxication and detoxification mixed type feed additive |
| CN106310235A (en) * | 2016-08-23 | 2017-01-11 | 四川恒通动物制药有限公司 | Veterinary drug composition and preparing method and use thereof |
| CN107114584A (en) * | 2017-06-13 | 2017-09-01 | 湖南农业大学 | The feed addictive and its making application method of a kind of milking sow |
| CN107660643A (en) * | 2017-11-06 | 2018-02-06 | 武汉九州神农药业有限责任公司 | Animal mycetism removing toxic substances additive |
| CN107897632A (en) * | 2017-11-10 | 2018-04-13 | 雷笑天 | A kind of preparation method of high-moisture herbage bundle natural fungicidal agent |
| CN108936046A (en) * | 2018-07-16 | 2018-12-07 | 新乡市佰牧饲料有限公司 | A kind of feed addictive taking off mould removing toxic substances for poultry |
| CN108935962A (en) * | 2018-09-30 | 2018-12-07 | 福建贝迪药业有限公司 | A kind of pulvis and preparation method thereof taking off mould protect liver for livestock and poultry |
| CN110200156A (en) * | 2019-06-03 | 2019-09-06 | 华北制药集团动物保健品有限责任公司 | It is a kind of improve feed intake piglet mixed feed additive and application |
| CN111248347A (en) * | 2020-01-15 | 2020-06-09 | 河南天昊鸿发生物技术有限公司 | Compound feed additive for livestock and poultry to remove mildew and detoxify and preparation method thereof |
| CN114009602A (en) * | 2021-11-11 | 2022-02-08 | 河北省农林科学院滨海农业研究所 | Fattening sheep feed additive and preparation method thereof |
| CN114145388A (en) * | 2021-12-02 | 2022-03-08 | 黑龙江领康生物科技有限公司 | Biological mildew removing agent for livestock feed and preparation method thereof |
| CN115380995A (en) * | 2022-07-25 | 2022-11-25 | 武汉新华扬生物股份有限公司 | Bacterium enzyme acid composite preparation and application thereof |
| CN115428862A (en) * | 2021-06-02 | 2022-12-06 | 菲吉乐科(南京)生物科技有限公司 | Antibacterial product produced by bacteriophage and lyase and preparation method thereof |
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Cited By (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104872399A (en) * | 2014-02-28 | 2015-09-02 | 雨润慕德生物科技（连云港）有限公司 | Interferon livestock and poultry micro-ecology additive |
| CN103859165B (en) * | 2014-03-06 | 2015-11-18 | 苏州万生源生物科技有限公司 | A kind of feed mycotoxin detoxification agent and preparation method thereof and application |
| CN103859165A (en) * | 2014-03-06 | 2014-06-18 | 苏州万生源生物科技有限公司 | Mycotoxin purification agent for feed and preparation method and application of agent |
| CN105010801A (en) * | 2015-06-17 | 2015-11-04 | 盐城恒兴饲料有限公司 | Low fishmeal feed for final grow-out period of carassius auratus gibelio and preparation method thereof |
| CN105594994A (en) * | 2015-12-30 | 2016-05-25 | 浙江大飞龙动物保健品有限公司 | Mildew-proof detoxication and detoxification mixed type feed additive |
| CN106310235B (en) * | 2016-08-23 | 2019-12-06 | 四川恒通动物制药有限公司 | veterinary drug composition and preparation method and application thereof |
| CN106310235A (en) * | 2016-08-23 | 2017-01-11 | 四川恒通动物制药有限公司 | Veterinary drug composition and preparing method and use thereof |
| CN107114584A (en) * | 2017-06-13 | 2017-09-01 | 湖南农业大学 | The feed addictive and its making application method of a kind of milking sow |
| CN107114584B (en) * | 2017-06-13 | 2021-04-13 | 湖南农业大学 | Feed additive for lactating sows and preparation and use methods thereof |
| CN107660643A (en) * | 2017-11-06 | 2018-02-06 | 武汉九州神农药业有限责任公司 | Animal mycetism removing toxic substances additive |
| CN107897632A (en) * | 2017-11-10 | 2018-04-13 | 雷笑天 | A kind of preparation method of high-moisture herbage bundle natural fungicidal agent |
| CN108936046A (en) * | 2018-07-16 | 2018-12-07 | 新乡市佰牧饲料有限公司 | A kind of feed addictive taking off mould removing toxic substances for poultry |
| CN108935962A (en) * | 2018-09-30 | 2018-12-07 | 福建贝迪药业有限公司 | A kind of pulvis and preparation method thereof taking off mould protect liver for livestock and poultry |
| CN110200156A (en) * | 2019-06-03 | 2019-09-06 | 华北制药集团动物保健品有限责任公司 | It is a kind of improve feed intake piglet mixed feed additive and application |
| CN111248347A (en) * | 2020-01-15 | 2020-06-09 | 河南天昊鸿发生物技术有限公司 | Compound feed additive for livestock and poultry to remove mildew and detoxify and preparation method thereof |
| CN115428862A (en) * | 2021-06-02 | 2022-12-06 | 菲吉乐科(南京)生物科技有限公司 | Antibacterial product produced by bacteriophage and lyase and preparation method thereof |
| CN114009602A (en) * | 2021-11-11 | 2022-02-08 | 河北省农林科学院滨海农业研究所 | Fattening sheep feed additive and preparation method thereof |
| CN114145388A (en) * | 2021-12-02 | 2022-03-08 | 黑龙江领康生物科技有限公司 | Biological mildew removing agent for livestock feed and preparation method thereof |
| CN115380995A (en) * | 2022-07-25 | 2022-11-25 | 武汉新华扬生物股份有限公司 | Bacterium enzyme acid composite preparation and application thereof |
| CN115380995B (en) * | 2022-07-25 | 2024-02-13 | 武汉新华扬生物股份有限公司 | Bacterial enzyme acid composite preparation and application thereof |
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Application publication date: 20140129 |