CN105594994A - Mildew-proof detoxication and detoxification mixed type feed additive - Google Patents
Mildew-proof detoxication and detoxification mixed type feed additive Download PDFInfo
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- CN105594994A CN105594994A CN201511010790.2A CN201511010790A CN105594994A CN 105594994 A CN105594994 A CN 105594994A CN 201511010790 A CN201511010790 A CN 201511010790A CN 105594994 A CN105594994 A CN 105594994A
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Abstract
The invention relates to a mildew-proof detoxication and detoxification mixed type feed additive, and belongs to the technical field of feed additives. The feed additive is prepared from the following raw materials in percentage by weight: 70 to 95 percent of modified montmorillonite, 0.4 to 0.8 percent of bacillus subtilis, 2 to 20 percent of yeast cell wall polysaccharide, 0.6 to 1 percent of glucose oxidase, 0.5 to 4 percent of methionine, 0.5 to 2 percent of alpha-mannatide and 0.5 to 4 percent of VC. The mildew-proof detoxication and detoxification mixed type feed additive has the advantages that the reasonable ingredient preparation is adopted; through reasonable use, mycotoxin can be adsorbed; the mildew growth is inhibited; the influence of mycotoxin on animal physiology is eliminated; the resistivity of animals on diseases is improved; the phenomenon of having loose bowels is reduced; the culture benefits are improved.
Description
Technical field
The invention belongs to field of feed additive technology, be specifically related to a kind of mildew-resistant detoxification removing toxic substances mixed feed and addAgent.
Background technology
Mould is a part for fungi, and mycotoxin is that a kind of that mould produces has the poisonous secondary of extensive chemical constitutionMetabolite, has toxicity widely to humans and animals. The current known mould that can produce mycotoxin has more than 150 to plant, according to estimatingMeter, annual nearly 25% cereal suffers various mould contaminations in the world. China most areas, particularly on the south the Changjiang riverDistrict, summer high temperature humidity, feed mold phenomenon is very general, and feed is very easily subject to mould contamination in processing, transporting procedures, evenForage crop may be subject to mould contamination in field, between harvest time. Mould can grow in feedstuff or feed, generationToxin can cause that Production of Livestock and Poultry power declines, reproductive capability obstacle, and severe patient can cause death. The production moment of herding is all over the world subject toTo the harm of mycotoxin, observablely to go mouldy not fearfully, user can delete and not use. Can the extraordinary raw material of outward appearance commonContaining the invisible mycotoxins such as zearalenone, FT, vomitoxin has become the main body that poison becomes, becomes motherPig miscarriage, stillborn foetus, produce pig search for food reduce or do not eat, speed of production is slow, Immunosuppression power, thereby cause that viral disease is attacked etc.The arch-criminal that phenomenon generally occurs, becomes the unsettled one of the main reasons of Swine Production effect. Meanwhile, mycotoxin also canResidual in animal products, bring safely very big hidden danger to human health. Therefore, mycotoxins in feed pollutes has become feed workThe problem that industry and animal husbandry can not be ignored in producing.
At present, on market, the constituent of mildew-resistant detoxifying agent is more single, generally adsorbs mould bacterium with sial silicateElement, as zeolite, kaolin, montmorillonite etc., can stop the absorption of mycotoxin in animal alimentary canal, thus reduced enter movingToxin amount in thing body, makes its toxicity alleviate or eliminate. But because Aluminosilicates adsorbent only can adsorb a kind of specificMycotoxin (the longest see be aflatoxin), and addition is larger, and therefore such product becomes for molecular weight and polarityChange various mycotoxin and be do not have resultful. Meanwhile, in absorbing mycotoxin, can with feed in vitamin, ore depositThe nutritional labelings such as material combine, and disturb the utilization of nutriment.
Therefore, exploitation one can mildew-resistant again can detoxification, can also remove toxin harm, repair the compound of impaired body and addAdding agent is a job that has theory significance and real value.
Summary of the invention
The problem existing for prior art, the object of the invention is to design provides a kind of mildew-resistant detoxification removing toxic substances mixed typeThe technical scheme of feed addictive, this feed addictive can absorbing mycotoxin, mildew-resistant, removing toxic substances, strengthens livestock and poultry resistance, repaiiesMultiple impaired body and effectively prevention mycotoxin endanger livestock and poultry.
Described a kind of mildew-resistant detoxification removing toxic substances mixed feed additive, is characterized in that comprising following percentage by weightRaw material:
Modified montmorillonite used 70-95%
Bacillus subtilis 0.4-0.8%
Yeast cell wall polysaccharide 2-20%
Glucose oxidase 0.6-1%
Methionine 0.5-4%
A-mannatide 0.5-2%
VC0.5-4%
Wherein hundred million of bacterium number >=1000 in every gram of bacillus subtilis.
Described a kind of mildew-resistant detoxification removing toxic substances mixed feed additive, is characterized in that comprising following percentage by weightRaw material:
Modified montmorillonite used 75-90%
Bacillus subtilis 0.5-0.7%
Yeast cell wall polysaccharide 4-16%
Glucose oxidase 0.8-1%
Methionine 1-3%
A-mannatide 1-2%
VC1-3%。
Described a kind of mildew-resistant detoxification removing toxic substances mixed feed additive, is characterized in that comprising following percentage by weightRaw material:
Modified montmorillonite used 85-90%
Bacillus subtilis 0.5-0.6%
Yeast cell wall polysaccharide 2-8%
Glucose oxidase 0.6-0.8%
Methionine 2-3%
A-mannatide 1-2%
VC2-3%。
Above-mentioned a kind of mildew-resistant detoxification removing toxic substances mixed feed additive using method is: at complete feed addition be5kg。
The effect of the each component of the present invention:
1) modified montmorillonite used: the montmorillonite of modification, every 1 gram of surface area is up to 800 square metres, with carbon content active20000 times, to mycotoxin have powerful absorption affinity and consumption little, and the clean adsorption layer of this technique fully exposes, and has moreAdsorption plane and clay electronics are combined space with mycotoxin electronics, thereby effectively remove the multiple mycotoxin in feed.
2) bacillus subtilis: the subtilin, polymyxins, the system that produce in bacillus subtilis thalli growth process are mouldRhzomorph, gramicidins isoreactivity material, these active materials have significantly the conditioned pathogen of pathogenic bacteria or autogenous infectionInhibitory action. Can consume rapidly the free oxygen in environment, cause enteron aisle hypoxemia, promote useful anaerobic bacteria growth, and produce lactic acidDeng organic acid, reduce enteron aisle pH value, indirectly suppress other pathogenic bacteria growth. Growing of stimulating animal immune organ, swashsT alive, bone-marrow-derived lymphocyte, improve immunoglobulin (Ig) and antibody horizontal, strengthens cellular immunity and humoral immune function, improves colony and exempt fromEpidemic disease power. Can self synthetic AMS, the enzyme such as protease, lipase, cellulase, in alimentary canal with animal body in disappearChanging enzyme together plays a role. The multiple B family vitamins such as energy synthetic vitamin B1, B2, B6, nicotinic acid, improve in animal body and disturbThe activity of element and macrophage.
3) yeast cell wall polysaccharide: the main component of yeast cell wall comprises glucan, mannosan, chitin and albumenMatter. The special construction that polysaccharide, protein and lipid on yeast cell wall produces, by hydrogen bond, ionic bond and hydrophobic effect powerMycotoxin is produced to absorption affinity.
4) glucose oxidase: glucose oxidase, as food additives, has transforming glucose and removes remaining oxygenPromote degrading mold toxin.
5) methionine: liver can purify the mycotoxin being absorbed by animal, the process of this purification is based on glutathioneRedox reaction, and methionine is conducive to the composition of glutathione, thereby additionally adds methionine and can reduce animalThe detrimental effect that growth and other performances produce.
6) a-mannatide: can remove vivotoxin, activating immune system, strengthens swinery resistance fast.
7) VC: the formation that can resist the MDA that mycotoxin causes. Therefore can be used as a kind of antioxidant system andFree radical quenchant is protected liver and spleen, makes cell membrane avoid the destruction of mycotoxin.
In sum, the present invention adopts the preparation of rational component, and rationally use can absorbing mycotoxin, mould fungus inhibitionGrowth, eliminates the impact of mycotoxin on animal physiological, improves the resistance of animal to disease, and minimizing is had loose bowels, and improves cultivation effectBenefit.
Detailed description of the invention
Further illustrate the present invention below in conjunction with embodiment.
Embodiment 1:
Modified montmorillonite used 76kg
Bacillus subtilis (hundred million/gram of bacterium number >=1000) 0.7kg
Yeast cell wall polysaccharide 15kg
Glucose oxidase 0.8kg
Methionine 3kg
A-mannatide 1.5kg
VC3kg
Production stage is as follows:
Step 1, take raw material by above weight portion;
Step 2, above raw material is mixed by weight, obtain finished product.
Embodiment 2:
Modified montmorillonite used 70kg
Bacillus subtilis (>=1,000 hundred million/gram) 0.8kg
Yeast cell wall polysaccharide 18.2kg
Glucose oxidase 1kg
Methionine 4kg
A-mannatide 2kg
VC4kg
Production stage is as follows:
Step 1, take raw material by above weight portion;
Step 2, above raw material is mixed by weight, obtain finished product.
Embodiment 3:
Modified montmorillonite used 85kg
Bacillus subtilis (>=1,000 hundred million/gram) 0.4kg
Yeast cell wall polysaccharide 6kg
Glucose oxidase 0.6kg
Methionine 3kg
A-mannatide 2kg
VC3kg
Production stage is as follows:
Step 1, take raw material by above weight portion;
Step 2, above raw material is mixed by weight, obtain finished product.
Embodiment 4:
Modified montmorillonite used 90kg
Bacillus subtilis (>=1,000 hundred million/gram) 0.6kg
Yeast cell wall polysaccharide 3.6kg
Glucose oxidase 0.8kg
Methionine 2kg
A-mannatide 1kg
VC2kg
Production stage is as follows:
Step 1, take raw material by above weight portion;
Step 2, above raw material is mixed by weight, obtain finished product.
Application examples:
1. a kind of mildew-resistant detoxification removing toxic substances pig of mixed feed additive to long-term storage of the present invention and the mould of poultry feedThe inhibition result of the test of growth is as follows:
Above data show, add the effectively growth of mould fungus inhibition toxin of the present invention in the feed of pig and poultry. ?Make above long-term storage in two months, also very effective. In this test, Moisture in Feed content is 13.5%.
2, a kind of mildew-resistant detoxification removing toxic substances mixed feed additive of the present invention has de-to the corn that is subject to mycotoxin harmToxic action:
Above data show, in contaminated raw material, add the present invention, further growth that can not only mould fungus inhibition, Er QiekeTo kill mould, raw material is had to stronger detoxification, thereby can retrieve the loss that raw material is caused by mould contamination, also canAlleviate the harm of mycotoxin to animal.
3, a kind of mildew-resistant detoxification removing toxic substances mixed feed additive of the present invention is subject to the feed of mould contamination to feedingAnimal has detoxication, and liver is removing toxic substances organ maximum in animal body, and this test is by measuring Animal Liver enzyme levelBright:
Wherein:
A group: normal corn;
B group: the corn that contains aflatoxin;
C group: the corn+embodiment of the present invention 1(5kg/T that contains aflatoxin);
D group: the corn+embodiment of the present invention 3(5kg/T that contains aflatoxin);
E group: the corn+embodiment of the present invention 4(5kg/T that contains aflatoxin).
Above data show, feed to pig and poultry and are subject to the corn of mycotoxin contamination can cause Animal Liver enzyme concentration levelRaising, illustrate that liver has carried out functional metabolism to mycotoxin, and add moldy feed of the present invention, feed after body,Have no the ANOMALOUS VARIATIONS of Animal Liver enzyme concentration level, illustrate that this additive can significantly reduce mycotoxin content, ensure liverThe metabolism of normal level, has good protective effect to body.
In sum, this invention is a kind of effectively mildew-resistant detoxification removing toxic substances mixed feed additive to feed, raw material, addsAdd the growth of the permanently effective mould fungus inhibition of the present invention's energy, mouldy feed or raw material are had to detoxification, and toolThere is detoxicating functions.
Claims (3)
1. a mildew-resistant detoxification removing toxic substances mixed feed additive, is characterized in that comprising the raw material of following percentage by weight:
Modified montmorillonite used 70-95%
Bacillus subtilis 0.4-0.8%
Yeast cell wall polysaccharide 2-20%
Glucose oxidase 0.6-1%
Methionine 0.5-4%
A-mannatide 0.5-2%
VC0.5-4%
Wherein hundred million of bacterium number >=1000 in every gram of bacillus subtilis.
2. a kind of mildew-resistant detoxification removing toxic substances mixed feed additive as claimed in claim 1, is characterized in that comprising following heavyThe raw material of amount percentage:
Modified montmorillonite used 75-90%
Bacillus subtilis 0.5-0.7%
Yeast cell wall polysaccharide 4-16%
Glucose oxidase 0.8-1%
Methionine 1-3%
A-mannatide 1-2%
VC1-3%。
3. a kind of mildew-resistant detoxification removing toxic substances mixed feed additive as claimed in claim 1, is characterized in that comprising following heavyThe raw material of amount percentage:
Modified montmorillonite used 85-90%
Bacillus subtilis 0.5-0.6%
Yeast cell wall polysaccharide 2-8%
Glucose oxidase 0.6-0.8%
Methionine 2-3%
A-mannatide 1-2%
VC2-3%。
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| CN201511010790.2A CN105594994A (en) | 2015-12-30 | 2015-12-30 | Mildew-proof detoxication and detoxification mixed type feed additive |
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Cited By (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106387359A (en) * | 2016-10-26 | 2017-02-15 | 深圳市裕农科技股份有限公司 | Feed additive capable of improving immunity and disease resistance and using method of feed additive |
| CN106472961A (en) * | 2016-10-26 | 2017-03-08 | 北京科润生科技发展有限公司 | The detoxifying agent of ochratoxin and its preparation technology in a kind of biodegradation feedstuff |
| CN106472962A (en) * | 2016-10-26 | 2017-03-08 | 北京科润生科技发展有限公司 | The detoxifying agent of 6-(10-hydroxy-6-oxo-trans-1-undecenyl)-.beta.-resorcylic acid lactone and its preparation technology in a kind of biodegradation feedstuff |
| CN106509590A (en) * | 2016-10-26 | 2017-03-22 | 北京科润生科技发展有限公司 | Detoxification agent for vomitoxin in biodegradable feed and preparation technology thereof |
| CN106578386A (en) * | 2016-12-20 | 2017-04-26 | 河南科技学院 | Thymol new application |
| CN106689982A (en) * | 2016-12-30 | 2017-05-24 | 新乡天祥药业有限公司 | Animal feed mold removal agent and preparation method thereof |
| CN106721932A (en) * | 2016-11-25 | 2017-05-31 | 中州大学 | A kind of feed biological de- mould dose of livestock and poultry and its application |
| CN107114584A (en) * | 2017-06-13 | 2017-09-01 | 湖南农业大学 | The feed addictive and its making application method of a kind of milking sow |
| CN107259141A (en) * | 2017-06-13 | 2017-10-20 | 湖南绿亨世源动物药业有限公司 | The feed addictive and its making application method of a kind of in-pig |
| CN107772195A (en) * | 2016-08-27 | 2018-03-09 | 瑞普（天津）生物药业有限公司 | One kind poultry poultry fodder takes off mould dose and preparation method thereof |
| CN107927338A (en) * | 2017-11-27 | 2018-04-20 | 山东迅达康兽药有限公司 | A kind of medicine, its preparation method and the application of anti-mildew verticillium toxin |
| CN108740443A (en) * | 2018-06-28 | 2018-11-06 | 河南普尼尔生物制药有限公司 | It is a kind of conditioning sow gastrointestinal tract function detoxification take off mould dose and preparation method thereof |
| CN108935962A (en) * | 2018-09-30 | 2018-12-07 | 福建贝迪药业有限公司 | A kind of pulvis and preparation method thereof taking off mould protect liver for livestock and poultry |
| CN109090351A (en) * | 2018-08-25 | 2018-12-28 | 郑州智谷工业技术有限公司 | A kind of glucose oxidase mixed feed additive |
| CN109527222A (en) * | 2018-11-15 | 2019-03-29 | 山西大学 | It is a kind of prevent and treat vomitoxin poisoning symptom feed addictive and its application |
| CN110452843A (en) * | 2019-08-01 | 2019-11-15 | 中国农业大学 | A kind of feeding bacillus subtilis and its application |
| CN111418756A (en) * | 2020-01-07 | 2020-07-17 | 中国农业大学 | Application of glucose oxidase and peroxidase in mycotoxin detoxification |
| CN113845121A (en) * | 2021-10-22 | 2021-12-28 | 龙岩学院 | Modified layered aluminosilicate for improving quality of breeding duck eggs and preparation method and application thereof |
| CN115380995A (en) * | 2022-07-25 | 2022-11-25 | 武汉新华扬生物股份有限公司 | Bacterium enzyme acid composite preparation and application thereof |
| CN116268218A (en) * | 2023-01-12 | 2023-06-23 | 云南壹祺牛生物科技有限公司 | Biological fermentation feed for cattle produced by utilizing vegetable tail leaves and preparation method thereof |
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| CN107772195A (en) * | 2016-08-27 | 2018-03-09 | 瑞普（天津）生物药业有限公司 | One kind poultry poultry fodder takes off mould dose and preparation method thereof |
| CN106472961A (en) * | 2016-10-26 | 2017-03-08 | 北京科润生科技发展有限公司 | The detoxifying agent of ochratoxin and its preparation technology in a kind of biodegradation feedstuff |
| CN106472962A (en) * | 2016-10-26 | 2017-03-08 | 北京科润生科技发展有限公司 | The detoxifying agent of 6-(10-hydroxy-6-oxo-trans-1-undecenyl)-.beta.-resorcylic acid lactone and its preparation technology in a kind of biodegradation feedstuff |
| CN106509590A (en) * | 2016-10-26 | 2017-03-22 | 北京科润生科技发展有限公司 | Detoxification agent for vomitoxin in biodegradable feed and preparation technology thereof |
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| CN106721932A (en) * | 2016-11-25 | 2017-05-31 | 中州大学 | A kind of feed biological de- mould dose of livestock and poultry and its application |
| CN106578386A (en) * | 2016-12-20 | 2017-04-26 | 河南科技学院 | Thymol new application |
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| CN107114584A (en) * | 2017-06-13 | 2017-09-01 | 湖南农业大学 | The feed addictive and its making application method of a kind of milking sow |
| CN107259141B (en) * | 2017-06-13 | 2021-06-22 | 湖南绿亨世源动物药业有限公司 | Feed additive for pregnant sows and preparation and use methods thereof |
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| CN110452843B (en) * | 2019-08-01 | 2021-02-19 | 中国农业大学 | Bacillus subtilis for feed and application thereof |
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| CN111418756A (en) * | 2020-01-07 | 2020-07-17 | 中国农业大学 | Application of glucose oxidase and peroxidase in mycotoxin detoxification |
| CN111418756B (en) * | 2020-01-07 | 2023-12-15 | 中国农业大学 | Application of glucose oxidase and peroxidase in mycotoxin detoxification |
| CN113845121A (en) * | 2021-10-22 | 2021-12-28 | 龙岩学院 | Modified layered aluminosilicate for improving quality of breeding duck eggs and preparation method and application thereof |
| CN113845121B (en) * | 2021-10-22 | 2023-09-29 | 龙岩学院 | Modified layered aluminosilicate for improving quality of duck eggs, and preparation method and application thereof |
| CN115380995A (en) * | 2022-07-25 | 2022-11-25 | 武汉新华扬生物股份有限公司 | Bacterium enzyme acid composite preparation and application thereof |
| CN115380995B (en) * | 2022-07-25 | 2024-02-13 | 武汉新华扬生物股份有限公司 | Bacterial enzyme acid composite preparation and application thereof |
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Application publication date: 20160525 |