CN108884140B - 修饰的嵌合受体及相关组合物和方法 - Google Patents
修饰的嵌合受体及相关组合物和方法 Download PDFInfo
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- CN108884140B CN108884140B CN201680080438.2A CN201680080438A CN108884140B CN 108884140 B CN108884140 B CN 108884140B CN 201680080438 A CN201680080438 A CN 201680080438A CN 108884140 B CN108884140 B CN 108884140B
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C07K14/70539—MHC-molecules, e.g. HLA-molecules
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211269666.8A CN116041538A (zh) | 2015-12-03 | 2016-12-02 | 修饰的嵌合受体及相关组合物和方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562262911P | 2015-12-03 | 2015-12-03 | |
| US62/262,911 | 2015-12-03 | ||
| US201662348130P | 2016-06-09 | 2016-06-09 | |
| US62/348,130 | 2016-06-09 | ||
| PCT/US2016/064861 WO2017096329A1 (en) | 2015-12-03 | 2016-12-02 | Modified chimeric receptors and related compositions and methods |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211269666.8A Division CN116041538A (zh) | 2015-12-03 | 2016-12-02 | 修饰的嵌合受体及相关组合物和方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN108884140A CN108884140A (zh) | 2018-11-23 |
| CN108884140B true CN108884140B (zh) | 2022-10-25 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211269666.8A Pending CN116041538A (zh) | 2015-12-03 | 2016-12-02 | 修饰的嵌合受体及相关组合物和方法 |
| CN201680080438.2A Active CN108884140B (zh) | 2015-12-03 | 2016-12-02 | 修饰的嵌合受体及相关组合物和方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211269666.8A Pending CN116041538A (zh) | 2015-12-03 | 2016-12-02 | 修饰的嵌合受体及相关组合物和方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US12139526B2 (enExample) |
| EP (2) | EP3383892B1 (enExample) |
| JP (2) | JP7184645B2 (enExample) |
| CN (2) | CN116041538A (enExample) |
| AU (1) | AU2016363025B2 (enExample) |
| CA (1) | CA3007262A1 (enExample) |
| ES (1) | ES2940607T3 (enExample) |
| MA (1) | MA43380A (enExample) |
| MX (1) | MX2018006789A (enExample) |
| WO (1) | WO2017096329A1 (enExample) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201404991YA (en) | 2012-02-23 | 2014-09-26 | Stage Cell Therapeutics Gmbh | Chromatographic isolation of cells and other complex biological materials |
| KR101605421B1 (ko) | 2014-03-05 | 2016-03-23 | 국립암센터 | B 세포 림프종 세포를 특이적으로 인지하는 단일클론항체 및 이의 용도 |
| SG11201608557UA (en) | 2014-04-16 | 2016-11-29 | Juno Therapeutics Gmbh | Methods, kits and apparatus for expanding a population of cells |
| US11400115B2 (en) | 2014-04-23 | 2022-08-02 | Juno Therapeutics, Inc. | Methods for isolating, culturing, and genetically engineering immune cell populations for adoptive therapy |
| EP3143134B1 (en) | 2014-05-15 | 2020-10-28 | National University of Singapore | Modified natural killer cells and uses thereof |
| EP3227323B1 (en) | 2014-12-03 | 2020-08-05 | Juno Therapeutics, Inc. | Methods and compositions for adoptive cell therapy |
| CA2971186A1 (en) | 2014-12-15 | 2016-06-23 | The Regents Of The University Of California | Cytotoxic molecules responsive to intracellular ligands for selective t cell mediated killing |
| US11253546B2 (en) | 2014-12-15 | 2022-02-22 | The Regents Of The University Of California | Bispecific OR-gate chimeric antigen receptor responsive to CD19 and CD20 |
| BR112017020058A2 (pt) * | 2015-03-20 | 2018-06-05 | Childrens Nat Medical Ct | processo para produzir uma célula-t específica, composição, banco de células-t específicas, método de tratamento, e, banco ou instalação de armazenamento de células. |
| MA45488A (fr) | 2015-10-22 | 2018-08-29 | Juno Therapeutics Gmbh | Procédés, kits et appareil de culture de cellules |
| KR20180108567A (ko) | 2015-10-22 | 2018-10-04 | 주노 테라퓨틱스 게엠베하 | 형질도입을 위한 방법, 키트, 제제 및 장치 |
| MA45489A (fr) | 2015-10-22 | 2018-08-29 | Juno Therapeutics Gmbh | Procédés de culture de cellules, kits et appareil associés |
| JP2019530440A (ja) | 2016-09-02 | 2019-10-24 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | インターロイキン6受容体α結合単鎖可変断片を含む方法および組成物 |
| KR102664453B1 (ko) * | 2017-02-21 | 2024-05-10 | 주식회사 유틸렉스 | Hla-dr car-t 조성물 및 그를 제조하고 사용하는 방법 |
| EP3601537A4 (en) | 2017-03-27 | 2021-01-13 | National University of Singapore | STIMULATING CELL LINES FOR EX VIVO EXPANSION AND ACTIVATION OF NATURAL KILLER CELLS |
| SG11201908492PA (en) | 2017-03-27 | 2019-10-30 | Nat Univ Singapore | Truncated nkg2d chimeric receptors and uses thereof in natural killer cell immunotherapy |
| CN110753555A (zh) | 2017-04-19 | 2020-02-04 | 得克萨斯州大学系统董事会 | 表达工程化抗原受体的免疫细胞 |
| IL270142B2 (en) | 2017-04-27 | 2025-05-01 | Juno Therapeutics Gmbh | Oligomeric particle reagents and methods of use thereof |
| TW201908335A (zh) * | 2017-07-25 | 2019-03-01 | 美國德州系統大學評議委員會 | 增強之嵌合抗原受體及其用途 |
| CN118345102A (zh) * | 2017-10-16 | 2024-07-16 | 莱蒂恩技术公司 | 用于用抗cd22免疫治疗来治疗癌症的组合物和方法 |
| BR112020008638A2 (pt) | 2017-11-01 | 2020-10-20 | Juno Therapeutics Inc | receptores de antígenos quiméricos específicos para antígenos de maturação de células b (bcma) |
| WO2019089855A1 (en) | 2017-11-01 | 2019-05-09 | Juno Therapeutics, Inc. | Process for generating therapeutic compositions of engineered cells |
| AU2018359907A1 (en) | 2017-11-06 | 2020-05-07 | Fred Hutchinson Cancer Center | Combination of a cell therapy and a gamma secretase inhibitor |
| CN111801348A (zh) | 2018-02-09 | 2020-10-20 | 新加坡国立大学 | 活化性嵌合受体及其在自然杀伤细胞免疫疗法中的用途 |
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| AU2016363025B2 (en) | 2021-04-08 |
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