DK3114455T3 - Robust antistof-oprensning - Google Patents
Robust antistof-oprensning Download PDFInfo
- Publication number
- DK3114455T3 DK3114455T3 DK15706374.4T DK15706374T DK3114455T3 DK 3114455 T3 DK3114455 T3 DK 3114455T3 DK 15706374 T DK15706374 T DK 15706374T DK 3114455 T3 DK3114455 T3 DK 3114455T3
- Authority
- DK
- Denmark
- Prior art keywords
- robust antibody
- cleaning
- antibody cleaning
- robust
- antibody
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/32—Bonded phase chromatography
- B01D15/325—Reversed phase
- B01D15/327—Reversed phase with hydrophobic interaction
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
- B01D15/361—Ion-exchange
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
- B01D15/3804—Affinity chromatography
- B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G, L chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461947761P | 2014-03-04 | 2014-03-04 | |
| PCT/EP2015/000361 WO2015131978A1 (en) | 2014-03-04 | 2015-02-18 | Robust antibody purification |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3114455T3 true DK3114455T3 (da) | 2020-04-06 |
Family
ID=52589333
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15706374.4T DK3114455T3 (da) | 2014-03-04 | 2015-02-18 | Robust antistof-oprensning |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10457720B2 (da) |
| EP (1) | EP3114455B1 (da) |
| JP (2) | JP7037275B2 (da) |
| KR (1) | KR102405382B1 (da) |
| CN (1) | CN106103477B (da) |
| CA (1) | CA2942134C (da) |
| DK (1) | DK3114455T3 (da) |
| ES (1) | ES2784638T3 (da) |
| SG (2) | SG10201807572PA (da) |
| WO (1) | WO2015131978A1 (da) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2970732C (en) * | 2014-12-15 | 2023-05-16 | Merck Patent Gmbh | Target molecule capture from crude solutions |
| US11186858B1 (en) | 2016-03-15 | 2021-11-30 | Fresenius Kabi Deutschland Gmbh | Methods for increasing biosimilarity |
| US11059856B2 (en) * | 2016-09-15 | 2021-07-13 | Klawego Gmbh & Co. Kg | Use of a polymeric mesh for the purification of macromolecules |
| CN106674403A (zh) * | 2017-01-03 | 2017-05-17 | 宏葵生物（中国）有限公司 | 一种用于增强免疫比浊法的聚苯乙烯微球制备方法及其应用 |
| WO2019164227A1 (ko) * | 2018-02-20 | 2019-08-29 | 고려대학교 산학협력단 | 엑소좀을 분리하기 위한 다중 컬럼 및 엑소좀 분리 방법 |
| JP7404689B2 (ja) * | 2018-08-06 | 2023-12-26 | 東ソー株式会社 | Ｆｃ結合性タンパク質を固定化した抗体吸着剤、およびそれを用いた抗体分離法 |
| JPWO2022260091A1 (da) * | 2021-06-10 | 2022-12-15 | ||
| EP4377361A1 (en) * | 2021-07-29 | 2024-06-05 | CSL Behring AG | Method of purifying immunoglobulin g and uses thereof |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4382124B1 (en) | 1958-07-18 | 1994-10-04 | Rohm & Haas | Process for preparing macroreticular resins, copolymers and products of said process |
| JPS5798504A (en) | 1980-12-11 | 1982-06-18 | Mitsubishi Monsanto Chem Co | Production of vinyl polymer |
| JP2534979B2 (ja) | 1984-12-27 | 1996-09-18 | 東ソー株式会社 | 液体クロマトグラフイ−用充てん剤 |
| JPS61141704A (ja) | 1985-11-11 | 1986-06-28 | Mitsubishi Kasei Vinyl Co | ビニル系重合体の製造方法 |
| US6251996B1 (en) * | 1998-12-09 | 2001-06-26 | The Dow Chemical Company | Gel-type copolymer bead and ion-exchange resins made therefrom |
| EP1179732B2 (en) | 2000-08-11 | 2012-02-29 | Rohm And Haas Company | Polymeric adsorbent and method of preparation |
| JP4319979B2 (ja) | 2002-04-26 | 2009-08-26 | ジェネンテック・インコーポレーテッド | タンパク質の非アフィニティ精製 |
| WO2005042569A1 (en) * | 2003-10-24 | 2005-05-12 | Amgen, Inc. | Process for purifying proteins in a hydrophobic interaction chromatography flow-through fraction |
| CN1927899A (zh) * | 2006-09-01 | 2007-03-14 | 烟台硕德新材料有限公司 | 一种微米级单分散共聚微球的制备方法 |
| AU2011214361C1 (en) * | 2010-02-12 | 2016-01-14 | Dpx Holdings B.V. | Single unit antibody purification |
| EP2726496B1 (en) | 2011-07-01 | 2018-04-04 | F.Hoffmann-La Roche Ag | Method for separation of monomeric polypeptides from aggregated polypeptides |
| WO2013028330A2 (en) * | 2011-08-19 | 2013-02-28 | Emd Millipore Corporation | Methods of reducing level of one of more impurities in a sample during protein purification |
| PL2970378T3 (pl) * | 2013-03-15 | 2021-12-06 | Biogen Ma Inc. | Chromatografia oddziaływań hydrofobowych białek w warunkach bez soli |
| US8946395B1 (en) * | 2013-10-18 | 2015-02-03 | Abbvie Inc. | Purification of proteins using hydrophobic interaction chromatography |
| CA2970732C (en) * | 2014-12-15 | 2023-05-16 | Merck Patent Gmbh | Target molecule capture from crude solutions |
-
2015
- 2015-02-18 EP EP15706374.4A patent/EP3114455B1/en active Active
- 2015-02-18 US US15/123,110 patent/US10457720B2/en active Active
- 2015-02-18 CN CN201580011575.6A patent/CN106103477B/zh active Active
- 2015-02-18 DK DK15706374.4T patent/DK3114455T3/da active
- 2015-02-18 SG SG10201807572PA patent/SG10201807572PA/en unknown
- 2015-02-18 WO PCT/EP2015/000361 patent/WO2015131978A1/en active Application Filing
- 2015-02-18 CA CA2942134A patent/CA2942134C/en active Active
- 2015-02-18 KR KR1020167027436A patent/KR102405382B1/ko active IP Right Grant
- 2015-02-18 JP JP2016555750A patent/JP7037275B2/ja active Active
- 2015-02-18 ES ES15706374T patent/ES2784638T3/es active Active
- 2015-02-18 SG SG11201607341SA patent/SG11201607341SA/en unknown
-
2020
- 2020-03-23 JP JP2020050723A patent/JP7153041B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| ES2784638T3 (es) | 2020-09-29 |
| JP2020128373A (ja) | 2020-08-27 |
| KR20160128411A (ko) | 2016-11-07 |
| JP2017509621A (ja) | 2017-04-06 |
| US20170073394A1 (en) | 2017-03-16 |
| EP3114455A1 (en) | 2017-01-11 |
| CA2942134A1 (en) | 2015-09-11 |
| WO2015131978A1 (en) | 2015-09-11 |
| KR102405382B1 (ko) | 2022-06-03 |
| CN106103477A (zh) | 2016-11-09 |
| JP7153041B2 (ja) | 2022-10-13 |
| SG10201807572PA (en) | 2018-10-30 |
| US10457720B2 (en) | 2019-10-29 |
| CN106103477B (zh) | 2021-08-17 |
| JP7037275B2 (ja) | 2022-03-16 |
| SG11201607341SA (en) | 2016-10-28 |
| EP3114455B1 (en) | 2020-01-15 |
| CA2942134C (en) | 2023-08-15 |
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