PL2970378T3 - Chromatografia oddziaływań hydrofobowych białek w warunkach bez soli - Google Patents

Chromatografia oddziaływań hydrofobowych białek w warunkach bez soli

Info

Publication number
PL2970378T3
PL2970378T3 PL14765488T PL14765488T PL2970378T3 PL 2970378 T3 PL2970378 T3 PL 2970378T3 PL 14765488 T PL14765488 T PL 14765488T PL 14765488 T PL14765488 T PL 14765488T PL 2970378 T3 PL2970378 T3 PL 2970378T3
Authority
PL
Poland
Prior art keywords
hydrophobic interaction
chromatography under
salt conditions
interaction protein
protein chromatography
Prior art date
Application number
PL14765488T
Other languages
English (en)
Inventor
Sanchayita Ghose
Yinying TAO
Original Assignee
Biogen Ma Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51537906&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2970378(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biogen Ma Inc. filed Critical Biogen Ma Inc.
Publication of PL2970378T3 publication Critical patent/PL2970378T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
PL14765488T 2013-03-15 2014-03-15 Chromatografia oddziaływań hydrofobowych białek w warunkach bez soli PL2970378T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361791238P 2013-03-15 2013-03-15
EP14765488.3A EP2970378B1 (en) 2013-03-15 2014-03-15 Hydrophobic interaction protein chromatography under no-salt conditions
PCT/US2014/029930 WO2014145208A1 (en) 2013-03-15 2014-03-15 Hydrophobic interaction protein chromatography under no-salt conditions

Publications (1)

Publication Number Publication Date
PL2970378T3 true PL2970378T3 (pl) 2021-12-06

Family

ID=51537906

Family Applications (1)

Application Number Title Priority Date Filing Date
PL14765488T PL2970378T3 (pl) 2013-03-15 2014-03-15 Chromatografia oddziaływań hydrofobowych białek w warunkach bez soli

Country Status (6)

Country Link
US (3) US9994609B2 (pl)
EP (2) EP2970378B1 (pl)
JP (1) JP6592426B2 (pl)
DK (1) DK2970378T3 (pl)
PL (1) PL2970378T3 (pl)
WO (1) WO2014145208A1 (pl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10023608B1 (en) 2013-03-13 2018-07-17 Amgen Inc. Protein purification methods to remove impurities
EP2970378B1 (en) 2013-03-15 2021-05-26 Biogen MA Inc. Hydrophobic interaction protein chromatography under no-salt conditions
WO2015131978A1 (en) * 2014-03-04 2015-09-11 Merck Patent Gmbh Robust antibody purification
TW201628649A (zh) 2014-10-09 2016-08-16 再生元醫藥公司 減少醫藥調配物中微可見顆粒之方法
SG11201900201YA (en) 2016-08-16 2019-02-27 Regeneron Pharma Methods for quantitating individual antibodies from a mixture
AU2017350807B2 (en) 2016-10-25 2022-07-07 Regeneron Pharmaceuticals, Inc. Methods and systems for chromatography data analysis
EP4467565A3 (en) 2016-12-21 2025-03-12 Amgen Inc. Anti-tnf alpha antibody formulations
CN118416215A (zh) 2017-09-19 2024-08-02 里珍纳龙药品有限公司 减少粒子形成的方法以及由其形成的组合物
TWI853823B (zh) 2018-07-02 2024-09-01 美商里珍納龍藥品有限公司 自混合物製備多肽之系統及方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5641870A (en) * 1995-04-20 1997-06-24 Genentech, Inc. Low pH hydrophobic interaction chromatography for antibody purification
US7427659B2 (en) * 2003-10-24 2008-09-23 Amgen Inc. Process for purifying proteins in a hydrophobic interaction chromatography flow-through fraction
AU2004315196B2 (en) 2004-01-30 2008-10-02 Amgen Inc. Process for purifying proteins
BRPI0518216C8 (pt) 2004-10-21 2017-03-21 Ge Healthcare Bio Sciences Ab ligante de cromatografia, métodos de preparação de uma matriz de separação, e de separação de um ou mais anticorpos de um ou mais outros compostos em uma amostra líquida, matriz de separação, e, coluna de cromatografia descartável.
US7408030B2 (en) * 2005-01-13 2008-08-05 North Carolina State University Purification of immunoglobulins using affinity chromatography and peptide ligands
CN101384623B (zh) * 2005-12-22 2013-07-24 常山凯捷健生物药物研发（河北）有限公司 白蛋白与治疗剂的预成型偶联物的制备方法
ES2439490T3 (es) 2007-01-05 2014-01-23 University Of Zurich Anticuerpo anti-beta amiloide y usos del mismo
EP2114984A2 (en) 2007-01-17 2009-11-11 Merck Serono S.A. Process for the purification of fc-containing proteins
US20110182809A1 (en) 2008-07-09 2011-07-28 University Of Zurich Method of Promoting Neurogenesis
AU2009269099B2 (en) 2008-07-09 2016-03-10 Biogen Ma Inc. Compositions comprising antibodies to LINGO or fragments thereof
US8497358B2 (en) 2008-12-19 2013-07-30 Takeda Pharmaceutical Company Limited Antibody purification method
WO2011046494A1 (en) 2009-10-12 2011-04-21 Ge Healthcare Bio-Sciences Ab Separation matrices
RU2603055C2 (ru) 2009-10-20 2016-11-20 Эббви Инк Выделение и очистка антител против il-13 с применением аффинной хроматографии с белком а
JP5699429B2 (ja) * 2009-12-18 2015-04-08 東ソー株式会社 Ｆｃレセプターの精製方法
WO2012078376A1 (en) 2010-12-08 2012-06-14 Amgen Inc. Ion exchange chromatography in the presence of an amino acid
MX2013014615A (es) 2011-06-16 2014-02-17 Dsm Ip Assets Bv Purificacion de anticuerpos por cromatografia de unidad unica.
DK2723379T3 (en) 2011-06-23 2018-10-15 Biogen Int Neuroscience Gmbh ANTI-ALPHA SYNUCLEIN BINDING MOLECULES
US9150645B2 (en) 2012-04-20 2015-10-06 Abbvie, Inc. Cell culture methods to reduce acidic species
US9249182B2 (en) * 2012-05-24 2016-02-02 Abbvie, Inc. Purification of antibodies using hydrophobic interaction chromatography
EP2919902B1 (en) 2012-11-13 2020-01-01 GE Healthcare BioProcess R&D AB Multimodal anion exchange matrices
EP2970378B1 (en) 2013-03-15 2021-05-26 Biogen MA Inc. Hydrophobic interaction protein chromatography under no-salt conditions
HK1222871A1 (zh) 2013-05-13 2017-07-14 Medimmune, Llc 具有最小单体分离的重组多克隆抗体多聚体的分离
NZ756750A (en) 2013-09-13 2022-05-27 Genentech Inc Methods and compositions comprising purified recombinant polypeptides
CA2942101A1 (en) * 2014-03-21 2015-09-24 Abbvie Inc. Anti-egfr antibodies and antibody drug conjugates

Also Published As

Publication number Publication date
EP3936515A1 (en) 2022-01-12
US20160024145A1 (en) 2016-01-28
JP6592426B2 (ja) 2019-10-16
EP2970378A4 (en) 2016-11-16
US20230391820A1 (en) 2023-12-07
US20190144495A1 (en) 2019-05-16
EP2970378A1 (en) 2016-01-20
EP2970378B1 (en) 2021-05-26
JP2016515529A (ja) 2016-05-30
DK2970378T3 (da) 2021-08-23
US11111269B2 (en) 2021-09-07
WO2014145208A1 (en) 2014-09-18
US9994609B2 (en) 2018-06-12

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