CN108883153A - 多价和多特异性ox40结合融合蛋白 - Google Patents
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- C07—ORGANIC CHEMISTRY
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- C07K2319/00—Fusion polypeptide
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662277027P | 2016-01-11 | 2016-01-11 | |
| US62/277,027 | 2016-01-11 | ||
| PCT/US2017/013070 WO2017123673A2 (en) | 2016-01-11 | 2017-01-11 | Multivalent and multispecific ox40-binding fusion proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108883153A true CN108883153A (zh) | 2018-11-23 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201780005939.9A Pending CN108883153A (zh) | 2016-01-11 | 2017-01-11 | 多价和多特异性ox40结合融合蛋白 |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US20170198051A1 (enExample) |
| EP (1) | EP3402507A4 (enExample) |
| JP (3) | JP7328761B2 (enExample) |
| KR (1) | KR20180098671A (enExample) |
| CN (1) | CN108883153A (enExample) |
| AU (2) | AU2017207318B2 (enExample) |
| BR (1) | BR112018013911A2 (enExample) |
| CA (1) | CA3009075A1 (enExample) |
| IL (2) | IL298686A (enExample) |
| MX (2) | MX2018008310A (enExample) |
| RU (1) | RU2022106508A (enExample) |
| SG (1) | SG11201805422WA (enExample) |
| WO (1) | WO2017123673A2 (enExample) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113330036A (zh) * | 2019-01-25 | 2021-08-31 | 信达生物制药(苏州)有限公司 | 结合pd-l1和ox40的双特异性抗体 |
| CN113490686A (zh) * | 2019-01-07 | 2021-10-08 | 拜科托莱夫有限公司 | 病原体结合蛋白 |
| WO2022002009A1 (zh) * | 2020-06-30 | 2022-01-06 | 和铂医药(上海)有限责任公司 | 靶向ox40的抗体及其制备方法和应用 |
| WO2023109901A1 (en) * | 2021-12-17 | 2023-06-22 | Shanghai Henlius Biotech, Inc. | Anti-ox40 antibodies and methods of use |
| CN118515763A (zh) * | 2024-07-23 | 2024-08-20 | 北京百普赛斯生物科技股份有限公司 | Il-6的抗体、检测试剂盒及其应用 |
| TWI907375B (zh) | 2019-12-20 | 2025-12-11 | 加拿大商木曾路生物科技公司 | 多肽、蛋白質複合物及其製造方法 |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
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| KR102410078B1 (ko) | 2012-05-31 | 2022-06-22 | 소렌토 쎄라퓨틱스, 인코포레이티드 | Pd-l1에 결합하는 항원 결합 단백질 |
| CA2978942A1 (en) | 2015-03-13 | 2016-09-22 | Cytomx Therapeutics, Inc. | Anti-pdl1 antibodies, activatable anti-pdl1 antibodies, and methods of use thereof |
| JP7328761B2 (ja) * | 2016-01-11 | 2023-08-17 | インヒブルクス インコーポレイテッド | 多価多重特異性ｏｘ４０結合融合タンパク質 |
| EP3487533A4 (en) * | 2016-07-20 | 2020-03-25 | IGM Biosciences, Inc. | MULTIMERE OX40-BINDING MOLECULES AND USES THEREOF |
| EP3494139B1 (en) | 2016-08-05 | 2022-01-12 | F. Hoffmann-La Roche AG | Multivalent and multiepitopic anitibodies having agonistic activity and methods of use |
| EP3515951B1 (en) * | 2016-09-23 | 2024-02-28 | Merus N.V. | Binding molecules that modulate a biological activity expressed by a cell |
| EA201991207A1 (ru) | 2016-12-19 | 2019-12-30 | Гленмарк Фармасьютикалс С.А. | Новые агонисты tnfr и их применение |
| IL269826B1 (en) | 2017-04-11 | 2025-09-01 | Inhibrx Inc | Multispecific polypeptide constructs having constrained cd3 binding and methods of using the same |
| TWI842672B (zh) | 2017-04-13 | 2024-05-21 | 美商艾吉納斯公司 | 抗ｃｄ１３７抗體及其使用方法 |
| KR20200016899A (ko) | 2017-06-01 | 2020-02-17 | 싸이톰스 테라퓨틱스, 인크. | 활성화가능 항-pdl1 항체, 및 이의 이용 방법 |
| TWI742336B (zh) * | 2017-12-29 | 2021-10-11 | 圓祥生命科技股份有限公司 | 調節免疫檢查點作為癌症治療的單特異性與雙特異性蛋白質、其醫藥組成物、其核酸、及其用途 |
| CN110305210B (zh) * | 2018-03-27 | 2023-02-28 | 信达生物制药(苏州)有限公司 | 新型抗体分子、其制备方法及其用途 |
| JP7724061B2 (ja) | 2018-04-11 | 2025-08-15 | インヒブルクス バイオサイエンシズ インコーポレイテッド | 制約されたｃｄ３結合を有する多重特異性ポリペプチド構築物ならびに関連する方法および使用 |
| TW202035451A (zh) | 2018-07-24 | 2020-10-01 | 美商英伊布里克斯公司 | 含有受限cd3結合域及受體結合區之多重特異性多肽構築體及其使用方法 |
| TW202019968A (zh) * | 2018-08-13 | 2020-06-01 | 美商英伊布里克斯公司 | Ox40結合多肽及其用途 |
| US12331320B2 (en) | 2018-10-10 | 2025-06-17 | The Research Foundation For The State University Of New York | Genome edited cancer cell vaccines |
| CN113166263A (zh) | 2018-10-11 | 2021-07-23 | 印希比股份有限公司 | Dll3单域抗体及其治疗性组合物 |
| CN120623346A (zh) | 2018-10-11 | 2025-09-12 | 因荷布瑞克斯生物科学公司 | Pd-1单结构域抗体及其治疗组合物 |
| US20230124851A1 (en) | 2018-10-11 | 2023-04-20 | Inhibrx, lnc. | B7h3 single domain antibodies and therapeutic compositions thereof |
| US20210340273A1 (en) | 2018-10-11 | 2021-11-04 | Inhlbrx, inc. | 5t4 single domain antibodies and therapeutic compositions thereof |
| WO2020102233A1 (en) * | 2018-11-13 | 2020-05-22 | Jn Biosciences Llc | Bispecific antibodies for activation of immune cells |
| WO2020102647A1 (en) * | 2018-11-15 | 2020-05-22 | Invenra Inc. | Multivalent receptor-clustering agonist antibody constructs and antigen binding proteins |
| WO2021073611A1 (zh) * | 2019-10-17 | 2021-04-22 | 江苏康宁杰瑞生物制药有限公司 | Ox40/pd-l1双特异性抗体 |
| WO2021084104A1 (en) * | 2019-10-30 | 2021-05-06 | Bioinvent International Ab | Tetravalent antibody molecules |
| CA3171363A1 (en) * | 2019-12-20 | 2021-06-24 | Kisoji Biotechnology Inc. | Polypeptides, protein complexes and method for making same |
| EP3940931A1 (de) | 2020-07-14 | 2022-01-19 | Siemens Aktiengesellschaft | Verfahren zur herstellung eines rotors einer asynchronmaschine |
| US20230287087A1 (en) * | 2020-07-29 | 2023-09-14 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Therapeutic and diagnostic vhh antibodies against sars-cov-2 and methods for their enhancement |
| WO2022243341A1 (en) * | 2021-05-18 | 2022-11-24 | Pieris Pharmaceuticals Gmbh | Lipocalin muteins with binding affinity for ox40 |
| TW202334203A (zh) * | 2021-11-19 | 2023-09-01 | 德商皮里斯製藥有限公司 | 新穎的ox40及pd-l1特異性融合蛋白 |
| EP4547270A2 (en) * | 2022-06-28 | 2025-05-07 | Beijing Starmab Biomed Technology Ltd | Monospecific and multi-specific antibodies |
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-
2017
- 2017-01-11 JP JP2018535298A patent/JP7328761B2/ja active Active
- 2017-01-11 CN CN201780005939.9A patent/CN108883153A/zh active Pending
- 2017-01-11 BR BR112018013911-4A patent/BR112018013911A2/pt not_active Application Discontinuation
- 2017-01-11 KR KR1020187022337A patent/KR20180098671A/ko not_active Ceased
- 2017-01-11 RU RU2022106508A patent/RU2022106508A/ru unknown
- 2017-01-11 CA CA3009075A patent/CA3009075A1/en active Pending
- 2017-01-11 IL IL298686A patent/IL298686A/en unknown
- 2017-01-11 WO PCT/US2017/013070 patent/WO2017123673A2/en not_active Ceased
- 2017-01-11 US US15/404,167 patent/US20170198051A1/en not_active Abandoned
- 2017-01-11 AU AU2017207318A patent/AU2017207318B2/en active Active
- 2017-01-11 EP EP17738885.7A patent/EP3402507A4/en active Pending
- 2017-01-11 MX MX2018008310A patent/MX2018008310A/es unknown
- 2017-01-11 SG SG11201805422WA patent/SG11201805422WA/en unknown
-
2018
- 2018-07-04 MX MX2024004017A patent/MX2024004017A/es unknown
- 2018-07-10 IL IL260531A patent/IL260531B2/en unknown
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2019
- 2019-03-07 US US16/295,332 patent/US11117972B2/en active Active
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2021
- 2021-08-10 US US17/398,851 patent/US12227584B2/en active Active
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2022
- 2022-09-28 JP JP2022154355A patent/JP2022185021A/ja active Pending
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2024
- 2024-01-30 AU AU2024200551A patent/AU2024200551A1/en active Pending
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2025
- 2025-02-26 JP JP2025028636A patent/JP2025081649A/ja active Pending
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| US20130018175A1 (en) * | 2009-12-14 | 2013-01-17 | Ablynx N.V. | Single variable domain antibodies against ox40l, constructs and therapeutic use |
| US20150355184A1 (en) * | 2012-12-21 | 2015-12-10 | Robert H. Pierce | Antibodies that bind to human programmed death ligand 1 (pd-l1) |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113490686A (zh) * | 2019-01-07 | 2021-10-08 | 拜科托莱夫有限公司 | 病原体结合蛋白 |
| CN113330036A (zh) * | 2019-01-25 | 2021-08-31 | 信达生物制药(苏州)有限公司 | 结合pd-l1和ox40的双特异性抗体 |
| TWI907375B (zh) | 2019-12-20 | 2025-12-11 | 加拿大商木曾路生物科技公司 | 多肽、蛋白質複合物及其製造方法 |
| WO2022002009A1 (zh) * | 2020-06-30 | 2022-01-06 | 和铂医药(上海)有限责任公司 | 靶向ox40的抗体及其制备方法和应用 |
| CN115461371A (zh) * | 2020-06-30 | 2022-12-09 | 和铂医药(上海)有限责任公司 | 靶向ox40的抗体及其制备方法和应用 |
| WO2023109901A1 (en) * | 2021-12-17 | 2023-06-22 | Shanghai Henlius Biotech, Inc. | Anti-ox40 antibodies and methods of use |
| CN118515763A (zh) * | 2024-07-23 | 2024-08-20 | 北京百普赛斯生物科技股份有限公司 | Il-6的抗体、检测试剂盒及其应用 |
| CN118515763B (zh) * | 2024-07-23 | 2024-11-01 | 北京百普赛斯生物科技股份有限公司 | Il-6的抗体、检测试剂盒及其应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2017123673A3 (en) | 2017-08-24 |
| JP2019504062A (ja) | 2019-02-14 |
| US20190263916A1 (en) | 2019-08-29 |
| AU2017207318A1 (en) | 2018-07-12 |
| JP2025081649A (ja) | 2025-05-27 |
| WO2017123673A2 (en) | 2017-07-20 |
| US20220106397A1 (en) | 2022-04-07 |
| EP3402507A4 (en) | 2019-08-07 |
| JP2022185021A (ja) | 2022-12-13 |
| US11117972B2 (en) | 2021-09-14 |
| EP3402507A2 (en) | 2018-11-21 |
| MX2018008310A (es) | 2019-01-28 |
| IL260531B1 (en) | 2023-01-01 |
| KR20180098671A (ko) | 2018-09-04 |
| US12227584B2 (en) | 2025-02-18 |
| JP7328761B2 (ja) | 2023-08-17 |
| AU2024200551A1 (en) | 2024-02-22 |
| NZ743731A (en) | 2025-06-27 |
| IL298686A (en) | 2023-01-01 |
| IL260531B2 (en) | 2023-05-01 |
| MX2024004017A (es) | 2024-05-08 |
| BR112018013911A2 (pt) | 2018-12-18 |
| AU2017207318B2 (en) | 2023-12-07 |
| CA3009075A1 (en) | 2017-07-20 |
| SG11201805422WA (en) | 2018-07-30 |
| US20170198051A1 (en) | 2017-07-13 |
| IL260531A (enExample) | 2018-08-30 |
| RU2018128629A (ru) | 2020-02-13 |
| RU2022106508A (ru) | 2022-04-05 |
| RU2018128629A3 (enExample) | 2020-06-16 |
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