CN108785200A

CN108785200A - A kind of antibacterial, anti-acne, crease-resistant silver ion moisture saver mask liquid, facial mask and preparation method thereof

Info

Publication number: CN108785200A
Application number: CN201810725318.4A
Authority: CN
Inventors: 沈平凡
Original assignee: Anhui Silver Lithium Biotechnology Development Co Ltd
Priority date: 2018-07-04
Filing date: 2018-07-04
Publication date: 2018-11-13
Anticipated expiration: 2038-07-04
Also published as: CN108785200B

Abstract

The present invention relates to household chemicals technical fields, and in particular to a kind of antibacterial, anti-acne, crease-resistant silver ion moisture saver mask liquid, facial mask and preparation method thereof.A kind of antibacterial, anti-acne, crease-resistant silver ion moisture saver mask liquid include at least following components by weight：Kuh-seng and 0.5~4 part of Rosmarinus officinalis extract, 2~10 parts of Gotu Kola P.E, 0.6~3 part of Baical Skullcap root P.E, 0.5~3 part of aloe extract, 0.001~0.03 part of silver ion solution.

Description

A kind of antibacterial, anti-acne, crease-resistant silver ion moisture saver mask liquid, facial mask and its preparation Method

Technical field

The present invention relates to household chemicals technical fields, and in particular to is protected to a kind of antibacterial, anti-acne, crease-resistant silver ion Wet facial mask liquid, facial mask and preparation method thereof.

Background technology

Facial mask is a kind of carrier of skin of face maintenance or cosmetics, is applied or is attached to and keeps certain time on the face, When the benefit materials in maintenance or cosmetics be absorbed by the skin or epidermis face in be harmful to skin health substance adsorbed by facial mask Afterwards, it is removed it by cleaning or removing, reaches facial skin quality maintenance or beautification purpose.At present facial mask product type and dosage form compared with It is more, such as paste, pulvis, creme, lotion and with non-woven fabrics, silk, biological fiber material be rely on tearing type hygenic towelette face Film etc..The beauty of facial mask or maintenance principle are exactly to be covered in face's certain time using it, be skin with extraneous air with it is dirty Dye is temporarily isolating, and improves skin temperature, and the pore expansion of skin promotes sweat gland secretion and metabolism, makes the oxygen content of skin Rise, excludes epidermal cell metabolism product and accumulation oil substances, while the moisture in facial mask and beneficiating ingredient infiltration The cuticula of epidermis, skin become soft, naturally bright flexible.Generally by facial mask be divided into mud paste type, tear-pull, gel-type, Four kinds of forms of hygenic towelette type.Especially hygenic towelette formula face paper, easy to use, effect is good, easily stored, the deep people's happiness liked to be beautiful Love, occupies very big share in cosmetics industry rapidly.It is also deep to be praised highly by manufacturer since storing is convenient, transportation cost is low, because This its consumption figure is very big.

The incidence of acne is higher in many facial skin diseases, also known as acne, dark sore, and Chinese medicine ancient times claim face sore, are skins Skin can common disease, frequently-occurring disease.If treatment is not in time or blindly treating can cause maxillofacial disease more serious, extend the course of disease, very It is unhealthful and vivid to leaving the scar for being difficult to eradicate, bring psychological shade to teenager.When face has acne, siberian crabapple System cannot resist bacterial infestation completely, while skin is more sensitive to extraneous stimulation and strong, and the mistaken ideas of existing research are recognized There is harmful effect to the healing of acne for skin care and cosmetics, therefore is avoided during general recommendations face acne using makeup Product, but skin of face can be made to keep moisture using plant extracts as the skin care item of primary raw material using some in fact, clearly relaxed Freely, it releives antiallergic, moisture-keeping crease-shedding, while killing skin surface harmful bacteria, accelerate wound healing, cutin-softening cell, prevent Pigment deposition is beneficial to elimination and skin barrier reparation of acne and small pox etc..

In view of the above technical problems, the present invention provides a kind of antibacterial, anti-acne, crease-resistant silver ion moisture saver mask liquid, faces Film is free of irritating sterilization and anticorrosion ingredient, skin surface bacterium can be effectively killed by the compounding of various plants extract, Accelerate wound healing, cutin-softening cell, prevent pigment deposition, there is good curative effect and excellent to acne and small pox Different moisture-keeping crease-shedding effect.It is the salubrious delicate fragrance of this product flavor, safe and non-toxic, nonirritant, it is used for a long time without any side effects.

Invention content

In order to solve the above-mentioned technical problem, the first aspect of the invention provide a kind of antibacterial, anti-acne, crease-resistant silver from Sub- moisture saver mask liquid includes at least following components by weight：Kuh-seng and 0.5~4 part of Rosmarinus officinalis extract, centella carry Take 2~10 parts of object, 0.6~3 part of Baical Skullcap root P.E, 0.5~3 part of aloe extract, 0.001~0.03 part of silver ion solution.

As a kind of preferred technical solution of the present invention, the antibacterial, anti-acne, crease-resistant silver ion moisture saver mask liquid, By weight, also contain following components：40~70 parts of water, 0.1~1.6 part of tackifier, 0.1~2 part of dipotassium glycyrrhizinate, high score 0.01~3 part of sub- moisturizer, 1~5 part of propylene glycol, 1~3 part of 1,3 butylene glycol, 0.1~1 part of Phenoxyethanol.

As a kind of preferred technical solution of the present invention, the antibacterial, anti-acne, crease-resistant silver ion moisture saver mask liquid, By weight, following components is included at least：1.5~4 parts of 50~65 parts of water, kuh-seng and Rosmarinus officinalis extract, centella extraction 5~10 parts of object, 0.6~2 part of Baical Skullcap root P.E, 1~3 part of aloe extract, 0.5~1.4 part of tackifier, dipotassium glycyrrhizinate 0.5 ~1.6 parts, 0.2~2.4 part of macromolecule moisturizer, 1~5 part of propylene glycol, 1~3 part of 1,3 butylene glycol, Phenoxyethanol 0.1~0.5 Part, 0.001~0.01 part of silver ion solution.

As a kind of preferred technical solution of the present invention, the kuh-seng and Rosmarinus officinalis extract are prepared bitter in raw material The mass ratio of ginseng and rosemary is 5~10：1.

As a kind of preferred technical solution of the present invention, the silver ion solution is chitin modified silver ion solution.

As a kind of preferred technical solution of the present invention, the tackifier are xanthans, carbomer, polyvinyl alcohol, bright Glue, gluconic acid, cornstarch, decyl glucan, polyvinylpyrrolidone, hydroxyethyl cellulose, cellulose acetate, acetic acid-fourth At least one of sour fiber, methylcellulose, sodium carboxymethylcellulose.

As a kind of preferred technical solution of the present invention, the tackifier are the mixing of xanthans and hydroxyethyl cellulose Object, mass ratio are 1~3：1.

As a kind of preferred technical solution of the present invention, the macromolecule moisturizer is selected from Sodium Hyaluronate, pyrrolidines At least one of keto carboxylic acid sodium, polyglutamic acid sodium, aloe polysaccharide, algal polysaccharides, collagen.

The second part of the present invention provides a kind of facial mask, and the facial mask includes：As the mask matrix of carrier, with And the antibacterial, anti-acne, crease-resistant silver ion moisture saver mask liquid, the antibacterial is adsorbed in the mask matrix, is dispelled Acne, crease-resistant silver ion moisture saver mask liquid.

As a kind of preferred technical solution of the present invention, the material of the mask matrix is selected from non-woven fabrics, silk, concept At least one of stealthy silk, hydrogel, pure cotton fiber, biological fiber, viscose rayon, tencel fiber, bamboo charcoal fiber.

The above-mentioned of the application and other features, aspect and advantage is more readily understood with reference to following detailed description.

The facial mask liquid property of the present invention is stablized, and the transparency, precipitation, smell are placed under high/low temperature condition and does not generate change Change.The facial mask of the present invention has excellent replenishing water and preserving moisture effect, while having reparation skin barrier, firm skin, promotes collagen Regeneration of albumen and other effects, can effectively pre- anti-wrinkle generation, have excellent anti-wrinkle effect.And the facial mask liquid pair of the present invention Escherichia coli, staphylococcus aureus, saccharomyces albicans and streptococcus also have propionibacterium acnes and have apparent antibacterial Effect, at the same it is non-stimulated to skin, there are excellent moisturizing, crease-resistant, antipruritic, anti-inflammatory effects.

Specific implementation mode

The detailed description for preferred implementation method of the invention below of participating in the election of and including embodiment this hair can be more easily understood Bright content.Unless otherwise defined, all technologies used herein and scientific terminology have common with fields of the present invention The normally understood identical meaning of technical staff.When there is a conflict, the definition in this specification shall prevail.

As used herein term " by ... prepare " it is synonymous with "comprising".Term "comprising" used herein, " comprising ", " having ", " containing " or its any other deformation, it is intended that cover non-exclusionism includes.For example, the combination comprising listed elements Object, step, method, product or device are not necessarily limited to those elements, but may include not expressly listed other elements or Such composition, step, method, product or the intrinsic element of device.

Conjunction " Consists of " excludes any element that do not point out, step or component.If in claim, this Phrase will make claim be closed, so that it is not included the material in addition to the material of those descriptions, but relative normal Except rule impurity.When being rather than immediately following after theme in the clause that phrase " Consists of " appears in claim main body, It is only limited to the element described in the clause；Other elements are not excluded except the claim as a whole.

Equivalent, concentration or other values or parameter are excellent with range, preferred scope or a series of upper limit preferred values and lower limit When the Range Representation that choosing value limits, this, which should be understood as, specifically discloses by any range limit or preferred value and any range Any pairing of lower limit or preferred value is formed by all ranges, regardless of whether the range separately discloses.For example, when open When range " 1 to 5 ", described range should be interpreted as including range " 1 to 4 ", " 1 to 3 ", " 1 to 2 ", " 1 to 2 and 4 to 5 ", " 1 to 3 and 5 " etc..When numberical range is described herein, unless otherwise stated, otherwise range intention includes its end Value and all integers and score in the range.

Singulative includes that plural number discusses object, unless the context clearly dictates otherwise." optional " or it is " arbitrary It is a kind of " refer to that the item described thereafter or event may or may not occur, and the description include situation that event occurs and The situation that event does not occur.

Approximate term in specification and claims is used for modifying quantity, and it is specific to indicate that the present invention is not limited to this Quantity further includes the modified part of the acceptable change without lead to related basic function close to the quantity.Phase It answers, modifies a numerical value with " about ", " about " etc., mean that the present invention is not limited to the exact numericals.In some examples, approximate Term likely corresponds to the precision of the instrument of measured value.In present specification and claims, range limits can be with Combination and/or exchange, these ranges include all subranges contained therebetween if not stated otherwise.

In addition, indefinite article "an" before element of the present invention or component and "one" quantitative requirement to element or component (i.e. occurrence number) unrestriction.Therefore "one" or "an" should be read as including one or at least one, and odd number The element or component of form also include plural form, unless the apparent purport of the quantity refers to singulative.

" polymer " means the polymerizable compound prepared by the monomer by the identical or different type of polymerization.Generic term " polymer " includes term " homopolymer ", " copolymer ", " terpolymer " and " copolymer ".

" copolymer " means the polymer prepared by polymerizeing at least two different monomers.Generic term " copolymer " includes (it is general with term " terpolymer " for term " copolymer " (its generally to refer to the polymer prepared by two kinds of different monomers) To refer to the polymer prepared by three kinds of different monomers).It also includes the polymerization manufactured by polymerization four or more monomer Object." blend " means the polymerization that two or more polymer is formed by mixing jointly by physics or chemical method Object.

Kuh-seng

Kuh-seng is the dry root of legume kuh-seng Sophora flavescens Ait..It is bitter in taste, it trembles with fear.The channel tropism thoughts of returning home, Liver, stomach, large intestine, bladder warp.Major function heat-clearing and damp-drying drug, desinsection, diuresis.For hot dysentery, have blood in stool, jaundice renal shutdown, leukorrhea with reddish discharge, Swelling of vulva pruritus vulvae, eczema, wet sore, pruitus, mange leprosy；Control trichomonas vaginitis outside.

Contain alkaloid in root：Matrine (matrine), oxymatrine (oxymatrine), N- oxidation sophocarpines (N- Oxysophocarpine), Sophoridine (sophoridine), the other matrine (- allomatrine) of dextrorotation, dextrorotation Iosmatrine (I-somatrine), dextrorotation sophoranl (sophoranol), (+) sophoranl N- oxides (sophoranol N-oxide), a left side Revolve sophocarpine (sophocarpine), left-handed sophoramine (sophoramine), dextrorotation-N-Methylcytisine (N- Methylcytisine), left-handed anagyrine (anagyrine), bap-iifoline (baptifoline).Also contain a variety of flavones in root Class compound：The new alcohol of kuh-seng (kushenol) A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, kuh-seng chalcone (kuraridin), kuh-seng chalcone alcohol (kuraridinol), kuh-seng alcohol (kurarinol), neokurarinol (neokurarinol), drop kuh-seng alcohol (norkurarinol), isokurarinone (isokurarinone), formoononetin (for- Mononetin), kurarinone (kurarinone), Vexibinol (norkurarinone), the new alcohol C of methyl kuh-seng (methylkushenol C), l- maackiains (lmaackiain), trifolirhizin (trifolirhizin) and Russian red clover are purple Wingceltis glucoside malonate (rtifolirhizin-6 "-O-malonate), kushenin (kushenin), different anhydroicartin (isoanhy-droicaritin), drop anhydroicartin (noranhydroicaritin), Xanthohumol (xan- Thohumol), different fulvic acid (isoxanthohumol), cyanidenon -7- glycosides (luteolin-7-glucoside). In addition, also containing triterpenoid saponin in root：Kuh-seng saponin (sophoraflavoside) I, II, III, IV, soyasaponins (soyasaponin) I and quinones：Kuh-seng quinone (kushequinone) A.

Matrine has active anticancer.Matrine can also be released by excited beta receptor, the beta receptor of especially excited maincenter Bronchial spasm and inhibits the release of antibody and slow reacting substance and generate antiasthmatic effect.Banlangen exclusive use has slight Analgesia and stable effect.Matrine can reduce the release of Anaphylactic mediator, be immunosuppressor.

Rosemary

Rosemary is the herb of labiate rosemary.Herb is containing hesperidine (hesperidin), diosmin (dios-min), shore Ji Huang glucoside (cirsimarin), in conjunction with ovum fruit fern glucoside (phegopolin), eupafolin -3-O- grapes Glucoside (eupafolin-3-O-glucoside), eupafolin -4-O- glycosides (eupafolin-4-O- Glucoside), homoplantaginin (homoplantagi-nin), Nepal's glycosides displayed (nepetrin), apiolin -7- glucose Glucoside (apigetrin), cyanidenon -3-O- glucuronides (luteolin-3-O-glucuronide), cyanidenon -7- Glycoside (luteolin-7-glucoside), 5- hydroxyl -4,7- dimethoxy flavones (5-hydroxy-4,7- Dimethoxyflavone), 4,5- dihydroxies -7- methoxy flavones (4,5-dihydroxy-7-methoxyflavone), rat-tail Careless amarolide (carnosol), rosmarinine (rosmaricine), isorosmaricine (isorosmaricine), table-α-perfume tree Lipidol (epi- α-amyrin), α-amyrin (α-amyrin), β-amyrin (β-amyrin), betulin (betulin), cupreol (β-sitosterol), Genkwanin (genkwanin), 7- ethyoxyl rosmanols (7- Ethoxyrosmanol), rosmanol (rosmanol), 7- methoxyl groups rosmanol (7-methoxyrosmanol), ursolic acid (ursolic acid), 19a-Hydroxyursolic Acid (19 α-hydroxyursolic acid), 2β-Hydroxyoleanolic Acid (2 β- Hydroxyoleanolic acid), betulic acid (betulinic acid), Rosmarinic acid (rosmarinic acid), mouse Tail oxalic acid (carnosic acid).In addition still (labiatic acid) containing labiatic acid.Root is containing the double quinones of Japanese yew (tarodione), the total shape elecampane quinone of 7 Alpha-hydroxies (7 α-hy-droxyroyleanone), sunken tanshinone (cryptotanshinone).Volatile oil containing antibacterial action in branch, leaf, wherein containing australene (α-pinene), lauro lene (camphene), 1,8- Cineoles (cineole), borneol (borneol), camphor (camphor), α-and beta-terpineol (terpineol), terpinene-4-alcohol (terpien-4-ol), verbenol (verbenol), Bronyl acetate (bornyl Ac-etate) etc..

Rosemary acrid flavour；It is warm-natured.Major function：Sweating；Invigorating the spleen；Calm the nerves；Analgesic, including various headaches；Prevent early stage de- Hair etc..The volatile oil of rosemary leave has golden yellow grape grape coccus, Escherichia coli, comma bacillus etc. the antibacterial action of affirmative.Fan Repeatedly fragrant alkali can also reinforce corticocerebral process of inhibition, there is hypnosis, anticonvulsant action.Contained diosmin can reduce in rosemary Capillary permeability, it is better than rutin to the increased therapeutic effect of capillary fragility, and toxicity is low.

Natural plants rosemary is not only a kind of spice berry, but also can therefrom extract antioxidant, Rosemary Oil And medicine intermediate, it is one of the plant of most Wheat Protein generally acknowledged at present.Its antioxidant content is mainly rat-tail The ingredients such as oxalic acid, carnosol, rosmanol, ursolic acid, Rosmarinic acid, these ingredients have anti-aging, anti-corrosion, antibacterial, It is anti-oxidant and other effects, it is widely used in food, cosmetics and medicines and health protection field.In addition to this due to the excellent antioxygen of rosemary Change, antiradical activities, thus it also has convergence and skin repair effect.Rosmarinus officinalis extract can not only effective stimulus Skin blood recycles, and has very strong compatibility with skin so that active ingredient can be absorbed by the skin.

As a kind of preferred technical solution of the present invention, the preparation method of the kuh-seng and Rosmarinus officinalis extract, at least Include the following steps：

By weight, dry radix sophorae and rosemary cured leaf are taken, 40 mesh sieve is smashed it through, is mixed uniformly, input In reaction kettle, ethyl alcohol is added, the mass ratio of the gross mass and ethyl alcohol of radix sophorae and rosemary cured leaf is 1：3~5,70~80 Refluxing extraction at DEG C, each extraction time are 0.3~2h, and extraction altogether twice, merges extracting solution；Activity is added into extracting solution The mass ratio of charcoal, activated carbon and extracting solution is 2~7：100,30min is stirred, 500 mesh filter clothes is crossed, is concentrated to dryness, obtains institute The kuh-seng and Rosmarinus officinalis extract stated.

The inventors discovered that kuh-seng and rosemary, which are carried out mixing extraction, can not only promote the dissolution of active principle, and The easily oxidizable and property easy to moisture absorption, the low-solubility of Rosmarinus officinalis extract in water of shrubby sophora extract are effectively improved, while bitter Ginseng and Rosmarinus officinalis extract show good synergistic effect in anti-inflammatory, antibacterial, skin repair etc..

Centella

Centella is the drying herb of samphire centella Centella asiatica (L.) Urb..Summer, Qiu Erji Harvesting removes silt, dries.Nature and flavor bitter, acrid, cold, Return liver, spleen, kidney channel.Major function clearing heat and promoting diuresis, removing toxicity for detumescence.For wet Hot jaundice, heatstroke diarrhea, sand drench blood strangury, carbuncle sore tumefacting virus, injury from falling down.

Triterpenoid containing a variety of α-botany bar gum alcohol type in centella, wherein having Asiaticoside (Asiaticoside), ginseng Withered Buddhist nun's glucoside (Thankuniside), isothankuniside (Isothankuniside), madecassoside (Madecas- Soside), brahmoside (Brahmoside), broken hot rice glucoside (Brah-minoside) and Brahmic acid (Brahmic acid), And madasiatic acid (Madasiatic acid) etc..In addition, still containing meso inositol (Meso-inositol), centella Sugared (Centellose, a kind of oligosaccharides), wax, carrot hydro carbons (Carotenoids), chlorophyll and Kaempferol, Quercetin and The glycosides displayed of glucose, rhamnose.Herb mainly contains triterpenic acid and triterpenoid saponin.Triterpene have asiatic acid (siatic acid), Brahmic acid (brahmic acid), different brahmic acid (isobrahmic acid) and birch skin acid (be-tulinic Acid) etc..Triterpenoid saponin has Asiaticoside (asiaticoside, madecassol), madecassoside (madecassoside), it centellas asiatica three glucosides (brahmoside) and four glucosides (brahminoside) of centellaing asiatica, and calls containing ginseng Withered glucoside (thankuniside) and the withered glucoside of different ginseng (isothankuniside).Separately containing Kaempferol and Quercetin and its glucoside, centella Alkali (hydrocotyline), meso inositol (inositol), centella oligosaccharide (centellose), sitosterol, vitamin C, carrotene, green volatile oil and resinoid.

Glucoside contained in centella has calm, stable effect；Its water extract also has antibacterial action.The alcohol extracting of centella For object without analgesic activity, Asiaticoside can treat skin ulcer, such as obstinate sexual trauma, cutaneous tuberculosis, leprosy.Centella can be tight It causes epidermis and corium coupling part, skin emolliency can be made, help to solve cutis laxa phenomenon (especially for postpartum mother)；Side It helps and collagen in skin corium is promoted to be formed, fibrin is made to regenerate；Can promote close connection between epidermis and corium and The increase that can inhibit adipocyte prevents hydroderma, obesity occurs.

As a kind of preferred technical solution of the present invention, the Gotu Kola P.E is prepared by percolation, institute The Extraction solvent stated is the ethanol water that concentration of volume percent is 30~70%.

As a kind of preferred technical solution of the present invention, the preparation method of the Gotu Kola P.E, include at least with Lower step：

It is 5~60 mesh to take dry centella herb to be crushed to granularity, is packed into diacolation column, compacting measures product The careless stacking volume of snow is added the Extraction solvent of 0.6~1 times of accumulated snow haystack product volume, 0.2~1h is impregnated at 30~70 DEG C；By 1~ The Extraction solvent of 3 times of accumulated snow haystacks product volumes flows through diacolation column and carries out seepage pressure effects from top to bottom, and Extraction solvent flow velocity is 0.2~ 1 times of accumulated snow haystack accumulates volume/hour, and the temperature of seepage pressure effects is 30~70 DEG C, collects percolate, and recycling design is concentrated under reduced pressure and obtains To Gotu Kola P.E；The Extraction solvent is the ethanol water that concentration of volume percent is 30~70%.

Radix scutellariae

Radix scutellariae is the dry root of labiate radix scutellariae Scutellaria baicalensis Georgi.It is bitter in taste, it trembles with fear. Return lung, courage, spleen, large intestine, small intestinl channel.Major function：Heat-clearing and damp-drying drug, purging intense heat and detonicating, hemostasis, tocolysis.It is uncomfortable in chest for damp-warm syndrome, heat temperature Evil of vomitting, damp and hot feeling of fullness, rush down dysentery, jaundice, cough with lung heat, hyperpyrexia polydipsia, blood-head tells nosebleed, carbuncle sore tumefacting virus, fetal irritability.

Radix scutellariae contains flavone compound：Baicalein (baicalein), neobaicalein (neobaicalein) i.e. skullcapflavone II (skullcapflavone II), baicalin (baicalin), wogonin (wogonin), wogonoside (wogono- Side), oroxylin A (oroxylin, oroxylin A), 7- methoxyl groups baicalein (7-methoxbaic alein), radix scutellariae Flavones (skullcapflavone) I, dihydro oroxylin A (dihydrooroxylin A), Chrysin (chrysin), 2,5, 8- trihydroxy -7- methoxy flavones (2,5,8-trihydroxy-7-methoxy-flavone), 2,5,8- trihydroxies -6,7- two Methoxy flavone (2,5,8-trihydroxy-6,7-dimethoxyflavone), 4,5,7- trihydroxy -6- methoxy flavanones (4,5,7-trhydroxy-6-methoxyflavanone), 2,3,5,6,7- penta hydroxy group flavanones (2,3,5,6,7- Pentahydroxyflavanone), wogonin -5- β-D-Glucose glucoside (wogonin-5- β-D-glucoside), 2- (3- Hydroxyl -4- methoxyphenyls)-ethyl -1-O- α-L- rhamnopyranosyls ([2- (3-hydroxy-4-methoxyphenyl) ethyl- 1-O- α-L-rhamnosyl), (1 → 3)-β-D (4- asafoetides acyl group)-glucose ((1 → 3)-β-D- (4-feruloyl)- Glucoside), Chrysin -6-C- α-L-arabinose glucoside (chrysin-6-C- β-D-glucoside-8-C- β-L- Arabinoside), Chrysin -6-C- α-L-arabinose glucoside -8-C- β-D-Glucose glucoside (chrysin-6-C- α-L- Arabi-noside-8-C- β-D-glucoside), (2S) -2,5,6,7- tetrahydroxys flavanones [(2S) -2,5,6,7- Terahydroxyflavanone], 5,7,2,6- kaempferols (5,7,2,7-tetrahydroxyflavone), 5,8- bis- Hydroxyl -6,7- dimethoxy flavones (5,8-dihydroxy-6,7-drimethoxyflavone), 5,7,4- trihydroxy -8- first Oxygroup flavones (5,7,4-trihydroxy-8-methoxyflavone), oroxylin A-7-O- glucuronides (oroxylinA-7-O-glucuronide), 5,7,2- trihydroxies methoxy flavone (5,7,2-trihyroxy-6- Methoxyflavone), 5,2- dihydroxy -6,7,8- trimethoxy flavones (5,2-dihydroxy-6,7,8- Trimethoxyfla-vone), 5- hydroxyls -7,8- dimethoxy flavones (5-hydroxy-7,8-dimethoxy-flavone), Norwogonin (norwogonin), dihydro baicalein (dihydro-baicalin), 5,7,2- trihydroxyflavones (5,7,2- Trihydroxyflavone), 5,7,2- trihydroxies -8,6- dimethoxy flavones (5,7,2-trihydroxy-8,6- Dimethoxyflavone), 5,7,2,5- tetrahydroxys -8,6- dimethoxy flavones, that is, viscidulin Ⅲ (5,7,2,5- Tetrahydroxy-8,6-dimethoxyflavone, vis-ciduiin III), 5,2,5- trihydroxy trimethoxy flavones (5, 2,5-trihy-droxy-6,7,8-trimethoxyflavone), baicalein -7-O- β-D- glucopyanosides (baicalein-7-O- β-D-glucopyranoside), 5,7,2- trihydroxy -8- methoxy flavones (5,7,2- Trhiyroxy-8-methoxyflavone), 5,2,6- trihydroxies -7,8- dimethoxy flavones, 5,2,6- trihydroxy -6- methoxies Base flavones (5,7,2-trihydroxy-6-methoxyflavone), 5,7,2,3- kaempferols (5,7,2,3- Trihydroxy-6-methoxyflavone), 5,7,2,3- kaempferols (5,7,2,3-tetrahydroxyflavone), 3,5,7,2,5,6- pentahydroxyflavones (3,5,7,2,6-pentahydroxyflavone) i.e. viscidulin Ⅰ (viscidulin I), (2S) -7,2,6- trihydroxy -5- methoxy flavanones [(2S) -7,2,6-trihydroxy-5- Methoxyflavanone], 2,6,2,4- tetrahydroxy -6- methoxyl group chalcones (2,6,2,4-tetrahydroxy-6- Methoxychalcone), 5,7,2,5- kaempferols (5,7,2,5-tetrahydroxyflavone), left-handed eriodictyol (eriodictyol), Sculellaria barbata kind plain (rivularin) and viscidulin Ⅲ -2-O- β-D- glucopyanosides (III -2-O- β-D-glucoplyranoside of viscidulin) etc..In addition also contain cupreol (β-sitosterol), rape oil Sterol (campesterol) and stigmasterol (stigmasterol).

Flavonoid substances in radix scutellariae have antibacterial anti-inflammatory, antipyretic, analgesia, anti-oxidant and removing free radical and other effects, together When it is strong to ultraviolet absorption ability.Extract baicalein and scutelloside can reduce the generation of free radical or effectively eliminate and generate Free radical, and can effectively delay skin aging and wrinkle generation.Medical field thinks that radix scutellariae is ideal nontoxic, harmless and effect The excellent natural substance having sun-screening function of fruit.Promotion of the Baical Skullcap root P.E to the activation of luciferase and to interferon secretion, this illustrates it To inhibiting dermatitis, increasing skin resistance has effect.Baical Skullcap root P.E has the ability for neutralizing histamine, so allergy can be prevented.

As a kind of preferred technical solution of the present invention, the preparation method of the Baical Skullcap root P.E includes at least following Step：

It takes radix scutellariae, crushing to sieve with 100 mesh sieve, the water of 7~10 times of quality is added, under conditions of 0~10 DEG C and pH=5~7 Twice, 15~40min, merges extracting solution every time, filters, and uses for stirring, ultrasonic (frequency 40kHz, power 100W) extraction The pH of filtrate is adjusted to 4~6 by malic acid, is heated to 50~60 DEG C and is kept the temperature 10~15h, precipitation is collected by filtration, washes, is dry, Obtain the Baical Skullcap root P.E.

Aloe

Aloe be liliaceous plant aloe barbadensis Miller Aloe barbadensis Miller, it be apply at present food, Widest kind in terms of drug and beauty.The main component of aloe has：(1) aloe gel composition is stabilized：Lignin, aloe Acid, saponin, anthraquinone, aloin, cinnamic acid quinone, barbaloin big, aloe-emodin, phenol, chrysophanic acid, anthracene etc.；(2) vitamin： Vitamin B1, folic acid, vitamin B2, vitamin C, niacinamide, vitamin E, vitamin B6, vitamin A, choline；(3) monosaccharide and Mucopolysaccharide：Cellulose, glucose, L- rhamnoses, glycosides dew sugar, xylose etc.；(4) enzyme：Oxidizing ferment, lipase, amylase, hydrogen peroxide Enzyme：(5) essential amino acid：Lysine, leucine, threonine, isoleucine, phenylalanine, valine etc..Scientific research is found Many ingredients have good nutrition moisten effect to human skin in aloe, and irritation is small, has skin whitening, prevents on skin Pigment formed and infiltration, softening skin effect, while also have analgesic disappear itch, antiperspirant deodorization, anti-acne, anti-senile plaque, it is right Pachylosis, facial wrinkles etc. have certain curative effect.Moisten beautification function：Aloe polysaccharide and vitamin have good battalion to skin Foster, moist, whitening effect.Aloe-emodin etc., which belongs to anthraquinone glycoside substance, can make hair soft and glossy, and with anti-dandruff Effect.Anti-aging effects：Mucus (i.e. protein) in aloe is the important component for preventing cell senescence and treating chronic allergic. Anti-sunlight function：The derivative of natural anthraquinone glycoside or anthracene in aloe, can absorb ultraviolet light, prevent that skin is red, foxiness generates.

As a kind of preferred technical solution of the present invention, the preparation method of the aloe extract includes at least following Step：

A certain amount of fresh aloe blade is extracted, prunes crust with knife, stripping and slicing is put into squeeze juice in juice extractor, with four Layer filtered through gauze, filter residue discard, and filtrate, which is set, preserves 10h in refrigerator (3~6 DEG C), then discard slag with four layers of filtered through gauze again, Obtain the aloe extract.

As a kind of preferred technical solution of the present invention, the preparation method of the silver ion solution includes at least following Step：

It is 1 by weight：1：1：1 takes dry Chinese red rose, sophora flower, cloves, lavender, crushes and is uniformly mixed, The ethanol water that the concentration of volume percent of 5~8 times of quality of addition is 15~25% thereto, 40~60 DEG C of extractions 5~ 10h, filtering, is concentrated under reduced pressure into no ethyl alcohol, obtains plant extracts；

Chitosan is taken, the aqueous acetic acid that volume fraction is 2%, the chitosan of configuration quality a concentration of 2% are dissolved in Aqueous acetic acid, stirring to chitosan are completely dissolved；Chitosan-acetic acid solution is taken, the AgNO of a concentration of 12.5mmol/L is added₃ Aqueous solution, chitosan-acetic acid solution and AgNO₃The volume ratio of aqueous solution is 20~30：1, stir 20~45min；Institute is added dropwise State plant extracts, the plant extracts and AgNO₃The volume ratio of aqueous solution is 20~50：1, it stirs, after 24~40min To the silver ion solution.

The inventors discovered that chitin modified silver ion solution, relative to common silver ion, antibiotic property is remarkably reinforced, and By the compounding with other plant extract, the dosage of common antiseptic and antibiotic agent is effectively reduced, enhances the facial mask liquid Safety.In addition, the silver ion solution of the present invention is prepared by special synthetic method, and good dispersion, not coagulation, The facial mask liquid has excellent stability.Silver is covered by inside chitosan in the silver ion solution of the present invention, not directly With skin contact, its irritation to skin is reduced, and by chitin modified, the interaction of silver and mask matrix increases By force, user's silver during using facial mask can play its antibacterial and promote cell growth, wound healing and other effects, simultaneously Non-stimulated, low sensitization, almost noresidue.

The second aspect of the invention provides the preparation of the antibacterial, anti-acne, crease-resistant silver ion moisture saver mask liquid Method at least includes the following steps：

By weight, it adds water in reaction kettle, is heated to 75~85 DEG C, stirred with the speed of 10~20r/min, Xiang Qi Middle addition tackifier, dipotassium glycyrrhizinate, macromolecule moisturizer, propylene glycol, 1,3-BDO, Phenoxyethanol, stirring are complete to material Fully dissolved keeps the speed of 10~20r/min to stir and cool down, is cooled to 35~45 DEG C, and kuh-seng and rosemary are added thereto Extract, Gotu Kola P.E, Baical Skullcap root P.E, aloe extract, silver ion solution keep the stirring speed of 10~20r/min PH adjusting agent is added to being uniformly mixed in degree, and it is 6~7 to adjust pH, is cooled to 25~34 DEG C, continues 15~30min of stirring, obtain The antibacterial, anti-acne, crease-resistant silver ion moisture saver mask liquid.

As a kind of preferred technical solution of the present invention, the pH adjusting agent is selected from calcium lactate, pyrophosphoric acid, ethoxy ammonia Base butyric acid, decoyl salicylic acid, diethyl sebacate, apple dioctyl phthalate, double third glycosides alcohol salicylates, folic acid, triethanolamine, lemon At least one of lemon acid, tartaric acid, malic acid, diethanol amine, ethylenediamine tetra-acetic acid, fumaric acid, phosphoric acid.

The third aspect of the invention provides a kind of facial mask, and the facial mask includes：As the mask matrix of carrier, with And the antibacterial, anti-acne, crease-resistant silver ion moisture saver mask liquid, the facial mask liquid is adsorbed in the mask matrix.

The facial mask liquid of the present invention is free of irritating sterilization and anticorrosion ingredient, passes through answering for various plants extract and silver ion With can effectively kill skin surface bacterium, accelerates wound healing, cutin-softening cell, prevents pigment deposition, to acne and acne Acne has good curative effect.The facial mask liquid opposite hymeniderm skin that the present invention is used for a long time has the facial skin of removing dirt, beautification Skin, antiphlogistic antibacterial mitigate the effects that acne, desalination whelk scar, while skin of face can be made smooth, careful, glossy, Can effectively pre- anti-wrinkle formation.The present invention is suitble to each stratum, each age group crowd to face without essence, pigment, preservative The needs of nursing are maintained, especially face has the skin patient of acne (whelk).The salubrious delicate fragrance of this product flavor, it is safe and non-toxic, It is nonirritant, it is used for a long time without any side effects.

The present invention is specifically described below by embodiment.It is necessarily pointed out that following embodiment is only used In the invention will be further described, it should not be understood as limiting the scope of the invention, professional and technical personnel in the field Some the nonessential modifications and adaptations made according to the content of aforementioned present invention, still fall within protection scope of the present invention.

In addition, if without other explanations, it is raw materials used to be all commercially available.

Embodiment 1：

Embodiment 1 provides a kind of antibacterial, anti-acne, crease-resistant silver ion moisture saver mask liquid and includes at least by weight Following components：0.5 part of 40 parts of water, kuh-seng and Rosmarinus officinalis extract, 2 parts of Gotu Kola P.E, 0.6 part of Baical Skullcap root P.E, aloe 0.5 part of extract, 0.1 part of tackifier, 0.1 part of dipotassium glycyrrhizinate, 0.01 part of macromolecule moisturizer, 1 part of propylene glycol, 1,3- fourths two 1 part of alcohol, 0.1 part of Phenoxyethanol, 0.001 part of silver ion solution.

The kuh-seng and Rosmarinus officinalis extract, it is 5 to prepare the mass ratio of kuh-seng and rosemary in raw material：1.

The preparation method of the kuh-seng and Rosmarinus officinalis extract, at least includes the following steps：

By weight, dry radix sophorae and rosemary cured leaf are taken, 40 mesh sieve is smashed it through, is mixed uniformly, input In reaction kettle, ethyl alcohol is added, the mass ratio of the gross mass and ethyl alcohol of radix sophorae and rosemary cured leaf is 1：5, at 70~80 DEG C Lower refluxing extraction, each extraction time are 1.5h, and extraction altogether twice, merges extracting solution；Activated carbon is added into extracting solution, activity The mass ratio of charcoal and extracting solution is 5：100, stir 30min, cross 500 mesh filter clothes, be concentrated to dryness, obtain the kuh-seng and Rosmarinus officinalis extract.

The Gotu Kola P.E is prepared by percolation, and the Extraction solvent is that concentration of volume percent is 70% ethanol water.

The preparation method of the Gotu Kola P.E, at least includes the following steps：

It is 40 mesh to take dry centella herb to be crushed to granularity, is packed into diacolation column, compacting measures accumulated snow Careless stacking volume is added the Extraction solvent of 0.8 times of accumulated snow haystack product volume, 1h is impregnated at 50 DEG C；2 times of accumulated snow haystacks are accumulated into volume Extraction solvent flow through diacolation column from top to bottom and carry out seepage pressure effects, Extraction solvent flow velocity is that 0.5 times of accumulated snow haystack accumulates volume/small When, the temperature of seepage pressure effects is 50 DEG C, collects percolate, and recycling design is concentrated under reduced pressure and obtains Gotu Kola P.E；Described carries It is the ethanol water that concentration of volume percent is 70% to take solvent.

The preparation method of the Baical Skullcap root P.E, at least includes the following steps：

It takes radix scutellariae, crushing to sieve with 100 mesh sieve, the water of 8 times of quality is added, stirring, ultrasound (frequency under conditions of 5 DEG C and pH=5 Rate is 40kHz, power 100W) extraction twice, each 30min merges extracting solution, filtering, using malic acid by the pH of filtrate 5 are adjusted to, be heated to 50 DEG C and keeps the temperature 12h, precipitation is collected by filtration, washing, drying obtain the Baical Skullcap root P.E.

The preparation method of the aloe extract, at least includes the following steps：

The tackifier are xanthans, for the cosmetics-stage product purchased from Xi'an Ze Long Bioisystech Co., Ltd.Institute The macromolecule moisturizer stated is selected from Sodium Hyaluronate, for the cosmetics-stage product purchased from Xi'an Ze Long Bioisystech Co., Ltd.

The silver ion solution is chitin modified silver ion solution.

The preparation method of the silver ion solution, at least includes the following steps：

It is 1 by weight：1：1：1 takes dry Chinese red rose, sophora flower, cloves, lavender, crushes and is uniformly mixed, The ethanol water that the concentration of volume percent of 8 times of quality is 18% is added thereto, 55 DEG C of extraction 7h are filtered, are concentrated under reduced pressure To no ethyl alcohol, plant extracts is obtained；

Chitosan is taken, the aqueous acetic acid that volume fraction is 2%, the chitosan of configuration quality a concentration of 2% are dissolved in Aqueous acetic acid, stirring to chitosan are completely dissolved；Chitosan-acetic acid solution is taken, the AgNO of a concentration of 12.5mmol/L is added₃ Aqueous solution, chitosan-acetic acid solution and AgNO₃The volume ratio of aqueous solution is 25：1, stir 25min；The plant is added dropwise to carry Take object, the plant extracts and AgNO₃The volume ratio of aqueous solution is 40：1, it stirs, it is molten that the silver ion is obtained after 30min Liquid.

The preparation method of the antibacterial, anti-acne, crease-resistant silver ion moisture saver mask liquid, at least includes the following steps：

By weight, it adds water in reaction kettle, is heated to 75~85 DEG C, stirred with the speed of 10~20r/min, Xiang Qi Middle addition tackifier, dipotassium glycyrrhizinate, macromolecule moisturizer, propylene glycol, 1,3-BDO, Phenoxyethanol, stirring are complete to material Fully dissolved keeps the speed of 10~20r/min to stir and cool down, is cooled to 35~45 DEG C, and kuh-seng and rosemary are added thereto Extract, Gotu Kola P.E, Baical Skullcap root P.E, aloe extract, silver ion solution keep the stirring speed of 10~20r/min PH adjusting agent is added to being uniformly mixed in degree, and it is 6~7 to adjust pH, is cooled to 25~34 DEG C, continues 15~30min of stirring, obtain The antibacterial, anti-acne, crease-resistant silver ion moisture saver mask liquid.The pH adjusting agent is malic acid or triethanolamine.

Embodiment 2：

Embodiment 2 provides a kind of antibacterial, anti-acne, crease-resistant silver ion moisture saver mask liquid and includes at least by weight Following components：4 parts of 70 parts of water, kuh-seng and Rosmarinus officinalis extract, 10 parts of Gotu Kola P.E, 3 parts of Baical Skullcap root P.E, aloe extraction 3 parts of object, 1.6 parts of tackifier, 2 parts of dipotassium glycyrrhizinate, 3 parts of macromolecule moisturizer, 5 parts of propylene glycol, 3 parts of 1,3 butylene glycol, benzene oxygen 1 part of ethyl alcohol, 0.03 part of silver ion solution.

The kuh-seng and Rosmarinus officinalis extract, it is 10 to prepare the mass ratio of kuh-seng and rosemary in raw material：1.

The preparation method is the same as that of Example 1 for the kuh-seng and Rosmarinus officinalis extract.

The Gotu Kola P.E is prepared by percolation, and the Extraction solvent is that concentration of volume percent is 30% ethanol water.

The preparation method is the same as that of Example 1 for the Gotu Kola P.E.

The preparation method is the same as that of Example 1 for the Baical Skullcap root P.E.

The preparation method is the same as that of Example 1 for the aloe extract.

The tackifier are carbomer, for the Acritamer 940 purchased from Guangzhou Nan Jia Chemical Industry Science Co., Ltd.Described Macromolecule moisturizer is selected from pyrrolidone sodium carboxylate, is purchased from Xun Nuo Chemical Industry Science Co., Ltd of Shantou City.

The silver ion solution is chitin modified silver ion solution.

The preparation method is the same as that of Example 1 for the silver ion solution.

The antibacterial, anti-acne, the preparation method is the same as that of Example 1 for crease-resistant silver ion moisture saver mask liquid.The pH tune It is malic acid or triethanolamine to save agent.

Embodiment 3：

Embodiment 3 provides a kind of antibacterial, anti-acne, crease-resistant silver ion moisture saver mask liquid and includes at least by weight Following components：1.5 parts of 50 parts of water, kuh-seng and Rosmarinus officinalis extract, 5 parts of Gotu Kola P.E, 0.6 part of Baical Skullcap root P.E, aloe 1 part of extract, 0.5 part of tackifier, 0.5 part of dipotassium glycyrrhizinate, 0.2 part of macromolecule moisturizer, 1 part of propylene glycol, 1,3 butylene glycol 1 Part, 0.1 part of Phenoxyethanol, 0.001 part of silver ion solution.

The kuh-seng and Rosmarinus officinalis extract, it is 8 to prepare the mass ratio of kuh-seng and rosemary in raw material：1.

The preparation method is the same as that of Example 1 for the Gotu Kola P.E.

The preparation method is the same as that of Example 1 for the aloe extract.

The tackifier are the mixture of xanthans and hydroxyethyl cellulose, mass ratio 1：1.The xanthans For the cosmetics-stage product purchased from Xi'an Ze Long Bioisystech Co., Ltd.Hydroxyethyl cellulose, CAS：0255-10-7 is purchased from Guangzhou Bo Feng Chemical Industry Science Co., Ltd.The macromolecule moisturizer is selected from polyglutamic acid sodium, and universe biology section is held purchased from Shaanxi Skill Co., Ltd, model CQ25513-46-6.

The silver ion solution is chitin modified silver ion solution.

Embodiment 4：

Embodiment 4 provides a kind of antibacterial, anti-acne, crease-resistant silver ion moisture saver mask liquid and includes at least by weight Following components：4 parts of 65 parts of water, kuh-seng and Rosmarinus officinalis extract, 10 parts of Gotu Kola P.E, 2 parts of Baical Skullcap root P.E, aloe extraction 3 parts of object, 1.4 parts of tackifier, 01.6 part of dipotassium glycyrrhizinate, 2.4 parts of macromolecule moisturizer, 5 parts of propylene glycol, 3 parts of 1,3 butylene glycol, 0.5 part of Phenoxyethanol, 0.01 part of silver ion solution.

The preparation method is the same as that of Example 1 for the Gotu Kola P.E.

The preparation method is the same as that of Example 1 for the aloe extract.

The tackifier are the mixture of xanthans and hydroxyethyl cellulose, mass ratio 3：1.The xanthans For the cosmetics-stage product purchased from Xi'an Ze Long Bioisystech Co., Ltd.Hydroxyethyl cellulose, CAS：0255-10-7 is purchased from Guangzhou Bo Feng Chemical Industry Science Co., Ltd.The macromolecule moisturizer is selected from Sodium Hyaluronate, to be purchased from the grand biology in Xi'an pool The cosmetics-stage product of Technology Co., Ltd..

The silver ion solution is chitin modified silver ion solution.

Embodiment 5：

Embodiment 5 provides a kind of antibacterial, anti-acne, crease-resistant silver ion moisture saver mask liquid and includes at least by weight Following components：3 parts of 60 parts of water, kuh-seng and Rosmarinus officinalis extract, 6 parts of Gotu Kola P.E, 2 parts of Baical Skullcap root P.E, aloe extraction 1.5 parts of object, 0.8 part of tackifier, 1.3 parts of dipotassium glycyrrhizinate, 1.2 parts of macromolecule moisturizer, 4 parts of propylene glycol, 1,3 butylene glycol 1.5 Part, 0.15 part of Phenoxyethanol, 0.003 part of silver ion solution.

The preparation method is the same as that of Example 1 for the Gotu Kola P.E.

The preparation method is the same as that of Example 1 for the aloe extract.

The tackifier are the mixture of xanthans and hydroxyethyl cellulose, mass ratio 1.6：1.The xanthan Glue is the cosmetics-stage product purchased from Xi'an Ze Long Bioisystech Co., Ltd.Hydroxyethyl cellulose, CAS：0255-10-7, purchase From Guangzhou Bo Feng Chemical Industry Science Co., Ltd.The macromolecule moisturizer is selected from Sodium Hyaluronate, to be purchased from Xi'an Ze Longsheng The cosmetics-stage product of object Technology Co., Ltd..

The silver ion solution is chitin modified silver ion solution.

Comparative example 1：

The specific implementation mode of comparative example 1 with embodiment 5, the difference is that, include kuh-seng and Rosmarinus officinalis extract.

Comparative example 2：

The specific implementation mode of comparative example 2 with embodiment 5, the difference is that, kuh-seng and Rosmarinus officinalis extract are replaced For etc. the shrubby sophora extract of quality and the mixture of Rosmarinus officinalis extract.The preparation method of the kuh-seng/Rosmarinus officinalis extract, It at least includes the following steps：By weight, dry radix sophorae/rosemary cured leaf is taken, 40 mesh sieve is smashed it through, is mixed It is even, it puts into reaction kettle, ethyl alcohol is added, the gross mass of radix sophorae/rosemary cured leaf and the mass ratio of ethyl alcohol are 1：3~5, Refluxing extraction at 70~80 DEG C, each extraction time are 0.3~2h, and extraction altogether twice, merges extracting solution；It is added into extracting solution The mass ratio of activated carbon, activated carbon and extracting solution is 2~7：100,30min is stirred, 500 mesh filter clothes is crossed, is concentrated to dryness, obtains To the kuh-seng/Rosmarinus officinalis extract.

Comparative example 3：

The specific implementation mode of comparative example 3 with embodiment 5, the difference is that, kuh-seng and Rosmarinus officinalis extract are replaced For etc. quality shrubby sophora extract.

Comparative example 4：

The specific implementation mode of comparative example 4 with embodiment 5, the difference is that, kuh-seng and Rosmarinus officinalis extract are replaced For etc. quality Rosmarinus officinalis extract.

Comparative example 5：

The specific implementation mode of comparative example 5 with embodiment 5, the difference is that, include silver ion solution.

Comparative example 6：

The specific implementation mode of comparative example 6 with embodiment 5, the difference is that, the preparation side of the silver ion solution Method at least includes the following steps：It is 1 by weight：1：1：1 takes dry Chinese red rose, sophora flower, cloves, lavender, crushes And be uniformly mixed, the ethanol water that the concentration of volume percent of 8 times of quality is 18%, 55 DEG C of extraction 7h, mistake are added thereto Filter, is concentrated under reduced pressure into no ethyl alcohol, obtains plant extracts；Configuration concentration is the AgNO of 12.5mmol/L₃Aqueous solution is added dropwise The plant extracts, the plant extracts and AgNO₃The volume ratio of aqueous solution is 40：1, it stirs, is obtained after 30min described Silver ion solution.

Comparative example 7：

The specific implementation mode of comparative example 7 with embodiment 5, the difference is that, the preparation side of the silver ion solution Method at least includes the following steps：Chitosan is taken, the aqueous acetic acid that volume fraction is 2% is dissolved in, configuration quality is a concentration of 2% chitosan aqueous acetic acid, stirring to chitosan are completely dissolved；Chitosan-acetic acid solution is taken, is added a concentration of 12.5mmol/L AgNO₃Aqueous solution, chitosan-acetic acid solution and AgNO₃The volume ratio of aqueous solution is 25：1, stir 25min；By It is added dropwise to the sodium citrate solution of a concentration of 5mmol/L, the sodium citrate solution and AgNO₃The volume ratio of aqueous solution is 40： 1, it stirs, the silver ion solution is obtained after 30min.

Performance evaluation：

Antibacterial, anti-acne, crease-resistant silver ion moisture saver mask liquid next life are obtained using Examples 1 to 5 and comparative example 1~7 Produce facial mask.Non-woven fabrics mask, every leaching liquid containing moisture saver mask 30g are impregnated when the present invention applies.

1. toxicology is tested

Select mouse carry out toxicology test, by the facial mask liquid of Examples 1 to 5 be configured to mass concentration be 25% it is water-soluble Liquid is tested, and it is shown that test result is as follows：

A. acute oral toxicity：It is nontoxic

B. eye irritation：It is resistant to very much

C. sensitization test (STT)：Without sensitization

2. facial mask performance evaluation

Choose 120 female volunteers, the age between 20~40 years old, volunteer's selection criteria：Sensibility skin, face There are the female volunteers of small pox or erythema.Volunteer is randomly divided into 12 groups, every group of 10 people use Examples 1 to 5 and right respectively The facial mask of ratio 1~7.After each group volunteer cleans face, using corresponding facial mask, facial mask is unfolded inwardly to be lightly spread in face, Flicking applies 15min to complete fitting, to the moisturizing effect, antipruritic, irritation, anti-inflammatory effects of facial mask after using 3 times, 4 weeks weekly It is evaluated, summarize data and calculates average value, evaluation method is：

A. moisturizing effect：5 points-effect is fine；4 points-effect is good；3 points-effect is general；2 points-there is no effect；

B. antipruritic：5 points-effect is fine；4 points-effect is good；3 points-effect is general；2 points-there is no effect；

C. irritation：5 points-non-stimulated；4 points-stimulate a little, but without it is red, itch；2 points-have stimulation, have it is red, itch；2 Point-stimulation, it is red, swollen；

D. anti-inflammatory effects：5 points-effect is fine, and the swelling and pain of small pox or erythema are subsided；4 points-effect is good, and small pox or erythema do not have There is pain；3 points-effect is general, and the swelling and pain of small pox or erythema also exist；2 points-there is no effect, small pox or erythema swelling and pain serious.

Table 1

	Moisturizing effect	It is antipruritic	Irritation	Anti-inflammatory effects
					Embodiment 1	3.9	4.0	4.8	3.9
Embodiment 2	3.8	4.1	4.7	4.0
					Embodiment 3	4.0	4.4	5	4.2
Embodiment 4	4.2	4.5	5	4.3
					Embodiment 5	4.5	4.7	5	4.4
Comparative example 1	3.2	3.0	3.6	2.5
					Comparative example 2	3.6	3.3	3.2	3.3
Comparative example 3	3.3	3.1	2.5	2.9
					Comparative example 4	3.4	3.1	2.6	3.0
Comparative example 5	3.8	3.8	5	3.5
					Comparative example 6	3.5	2.8	3.4	3.2
Comparative example 7	3.6	3.2	3.7	3.0

3. stabilizing effect is evaluated

A. facial mask liquid is placed in (45 ± 2) DEG C electro-heating standing-temperature cultivator 30 days, its stability is observed after restoring room temperature； B. facial mask liquid is placed in the refrigerator of (- 5 ± 2) DEG C 30 days, its stability is observed after restoring room temperature.

Observation item：The facial mask liquid transparency, precipitation, smell variation etc., if facial mask liquid still maintains transparent, without precipitation, nothing Smell changes, then is recorded as stablizing, otherwise be recorded as unstable.Test result is as shown in table 2.

4. bactericidal property

A. the inhibition of staphylococcus aureus, Escherichia coli is tested

Facial mask made from Examples 1 to 5 and comparative example 1~7 is cut into 5 × 5cm²Print, place it in enclosed environment (room temperature, normal humidity) places culture of Escherichia coli, the staphylococcus aureus of open culture in the enclosed environment Culture, saccharomyces albicans culture and streptococcus culture after placing 12h, measure the clump count on the print (CFU/mL), specific measurement method is to take out the sample to be placed in the deionized water of 100mL, impregnates 3h, filtering takes 1mL Sample cultivates 48h at 37 DEG C, carries out total plate count measurement.

B. the inhibition of propionibacterium acnes is tested

Everybody generally believes that mass propagation of the propionibacterium acnes in hair follicle is to induce acne or small pox and cause now A kind of its very important factor deteriorated, therefore, research are evaluation product anti-acne work(to the inhibiting effect of propionibacterium acnes One important method of effect.

Specific test method：(1) it weighs 18.5g biosynthetic human insulins (BHI) powder to be dissolved in 500mL water, sterilize After BHI culture mediums are made, by propionibacterium acnes inoculation to BHI culture mediums, 37 DEG C of anaerobism trainings in bag occurs for anaerobism It supports 48h and shaking is uniformly spare, a small amount of bacterial strain is separately taken to be applied on glass slide, dyeing is fixed using the method for Grain stain, then It places it under 100 × 100 oil mirror and executes microscopy, visible chromabacterium biolaceum under mirror is micro-bend in rodlike or rod-shaped, no miscellaneous bacteria life It is long.

(2) lysis solution of propionibacterium acnes culture is diluted into 100 times of (OD₆₀₀About 0.02).By Examples 1 to 5 and Facial mask liquid made from comparative example 1~7 is each configured to the aqueous solution of 200mg/mL, doubling dilution at 100,50.0,25.0, The various concentration sample solution of 12.5mg/mL.

(3) the above-mentioned diluted 90 μ L of solution containing propionibacterium acnes are added per hole into sterile 96 orifice plate, add 10 μ L of diluted sample solution so that drug final concentration of 20mg/mL, 10mg/mL, 5mg/mL, 2.5mg/mL and 1.25mg/ mL；Add 10 μ L sterile salines as negative control using 90 μ L bacterium solutions；Positive control is by 10 μ g/mL, 5 μ g/mL and 2.5 μ The ampicillin sodium solution composition of g/mL.Above-mentioned sample is transferred to 37 DEG C of constant-temperature table incubator, the training of 250r/min anaerobism Support 48h.

(4) solution O D after every group of sample is mixed with propionibacterium acnes is measured with microplate reader₆₀₀Light absorption value.Do not have completely There is the drug concentration in light absorption hole as minimal inhibitory concentration.It takes after the bacterium solution conventional line Grain stain of not light absorption with micro- Spectroscopy proves the growth whether there is or not propionibacterium acnes.

(5) method of tablet culture repetition measurement is used to detect the minimal inhibitory concentration for above-mentioned model propionibacterium acnes Value, the results are shown in table below.

2 performance characterization of table is tested

The facial mask liquid property of the present invention is stablized, and the transparency, precipitation, smell are placed under high/low temperature condition and does not generate change Change, and also has propionibacterium acnes to Escherichia coli, staphylococcus aureus, saccharomyces albicans and streptococcus and have and is bright Aobvious fungistatic effect, at the same it is non-stimulated to skin, there are excellent moisturizing, crease-resistant, antipruritic, anti-inflammatory effects.

Example above-mentioned is merely illustrative, some features for explaining the method for the invention.Appended right is wanted The range as wide as possible for being intended to require to be contemplated that is sought, and embodiments as presented herein is only according to all possible implementation The explanation of the embodiment of the selection of the combination of example.Therefore, the purpose of applicant is that the attached claims are not illustrated this hair The exemplary selectional restriction of bright feature.Some numberical ranges used also include sub- model in the claims It encloses, the variation in these ranges should also be construed to be covered by the attached claims in the conceived case.

Claims

1. a kind of antibacterial, anti-acne, crease-resistant silver ion moisture saver mask liquid, which is characterized in that by weight, include at least following Component：Kuh-seng and 0.5~4 part of Rosmarinus officinalis extract, 2~10 parts of Gotu Kola P.E, 0.6~3 part of Baical Skullcap root P.E, aloe carry Take 0.5~3 part of object, 0.001~0.03 part of silver ion solution.

2. antibacterial as described in claim 1, anti-acne, crease-resistant silver ion moisture saver mask liquid, which is characterized in that by weight Meter, also contains following components：40~70 parts of water, 0.1~1.6 part of tackifier, 0.1~2 part of dipotassium glycyrrhizinate, macromolecule moisturizer 0.01~3 part, 1~5 part of propylene glycol, 1~3 part of 1,3 butylene glycol, 0.1~1 part of Phenoxyethanol.

3. antibacterial as claimed in claim 2, anti-acne, crease-resistant silver ion moisture saver mask liquid, which is characterized in that by weight Meter includes at least following components：50~65 parts of water, kuh-seng and 1.5~4 parts of Rosmarinus officinalis extract, Gotu Kola P.E 5~10 Part, 0.6~2 part of Baical Skullcap root P.E, 1~3 part of aloe extract, 0.5~1.4 part of tackifier, 0.5~1.6 part of dipotassium glycyrrhizinate, 0.2~2.4 part of macromolecule moisturizer, 1~5 part of propylene glycol, 1~3 part of 1,3 butylene glycol, 0.1~0.5 part of Phenoxyethanol, silver from 0.001~0.01 part of sub- solution.

4. antibacterial as described in claim 1, anti-acne, crease-resistant silver ion moisture saver mask liquid, which is characterized in that the kuh-seng And Rosmarinus officinalis extract, it is 5~10 to prepare the mass ratio of kuh-seng and rosemary in raw material：1.

5. antibacterial as described in claim 1, anti-acne, crease-resistant silver ion moisture saver mask liquid, which is characterized in that the described silver from Sub- solution is chitin modified silver ion solution.

6. antibacterial as claimed in claim 2, anti-acne, crease-resistant silver ion moisture saver mask liquid, which is characterized in that the thickening Agent is xanthans, carbomer, polyvinyl alcohol, gelatin, gluconic acid, cornstarch, decyl glucan, polyvinylpyrrolidone, hydroxyl At least one of ethyl cellulose, cellulose acetate, acetic acid-butyric acid fiber, methylcellulose, sodium carboxymethylcellulose.

7. antibacterial as claimed in claim 6, anti-acne, crease-resistant silver ion moisture saver mask liquid, which is characterized in that the thickening Agent is the mixture of xanthans and hydroxyethyl cellulose, and mass ratio is 1~3：1.

8. antibacterial as claimed in claim 2, anti-acne, crease-resistant silver ion moisture saver mask liquid, which is characterized in that the high score Sub- moisturizer is in Sodium Hyaluronate, pyrrolidone sodium carboxylate, polyglutamic acid sodium, aloe polysaccharide, algal polysaccharides, collagen At least one.

9. a kind of facial mask, which is characterized in that the facial mask includes：As the mask matrix of carrier, and as claim 1~ 8 any one of them antibacterials, anti-acne, crease-resistant silver ion moisture saver mask liquid are adsorbed in the mask matrix described anti- Bacterium, anti-acne, crease-resistant silver ion moisture saver mask liquid.

10. facial mask as claimed in claim 9, which is characterized in that the material of the mask matrix be selected from non-woven fabrics, silk, At least one of concept stealth silk, hydrogel, pure cotton fiber, biological fiber, viscose rayon, tencel fiber, bamboo charcoal fiber.