CN108699528A - 在先天性巨结肠症中通过衍生自多能干细胞的人肠神经嵴谱系可行的基于细胞的治疗和药物开发 - Google Patents

在先天性巨结肠症中通过衍生自多能干细胞的人肠神经嵴谱系可行的基于细胞的治疗和药物开发 Download PDF

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CN108699528A
CN108699528A CN201680082392.8A CN201680082392A CN108699528A CN 108699528 A CN108699528 A CN 108699528A CN 201680082392 A CN201680082392 A CN 201680082392A CN 108699528 A CN108699528 A CN 108699528A
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L·施图德
F·法塔希
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Memorial Sloan Kettering Cancer Center
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CN201680082392.8A 2015-12-23 2016-12-22 在先天性巨结肠症中通过衍生自多能干细胞的人肠神经嵴谱系可行的基于细胞的治疗和药物开发 Pending CN108699528A (zh)

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US201562387468P 2015-12-23 2015-12-23
US62/387,468 2015-12-23
PCT/US2016/068430 WO2017112901A1 (en) 2015-12-23 2016-12-22 Cell-based treatment and drug discovery in hirschsprung's disease enabled by pluripotent stem cell-derived human enteric neural crest lineages

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US (1) US12371662B2 (https=)
EP (1) EP3414322A4 (https=)
JP (2) JP7549442B2 (https=)
KR (1) KR20180093063A (https=)
CN (1) CN108699528A (https=)
AU (2) AU2016377701B2 (https=)
CA (1) CA3009509A1 (https=)
IL (1) IL260214B2 (https=)
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CN110747276A (zh) * 2019-11-22 2020-02-04 山东大学齐鲁医院 Bace2作为胶质瘤预后/诊断/治疗标志物的应用
WO2022199682A1 (zh) * 2021-03-26 2022-09-29 广州市妇女儿童医疗中心 先天性巨结肠的诊断或早期诊断标志物及其应用

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JP7094567B2 (ja) * 2017-04-27 2022-07-04 国立大学法人京都大学 神経堤細胞および交感神経細胞の製造方法
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AU2019401518B2 (en) * 2018-12-21 2026-02-26 The Regents Of The University Of California Method of producing enteric neurons and uses thereof
US12600943B2 (en) 2019-02-01 2026-04-14 The University Of Hong Kong Innervated organoid compositions and methods of making same
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CA3162011A1 (en) * 2019-12-19 2021-06-24 Rodolphe SORET Use of glial cell line-derived neurotrophic factor (gdnf) for the treatment of enteric neuropathies
US20230126711A1 (en) * 2020-03-25 2023-04-27 The Regents Of The University Of California Enteric nitrergic neurons and methods of using the same
WO2022046771A1 (en) * 2020-08-24 2022-03-03 The Johns Hopkins University Juvenile protective factors to arrest and reverse aging in the enteric nervous system
US20240252545A1 (en) * 2021-05-07 2024-08-01 Children's Hospital Los Angeles Methods for Making Stem Cell-Derived Enteric Neural Crest Cells and Their Use in Enteric Neuropathy Treatment
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110747276A (zh) * 2019-11-22 2020-02-04 山东大学齐鲁医院 Bace2作为胶质瘤预后/诊断/治疗标志物的应用
CN110747276B (zh) * 2019-11-22 2020-06-30 山东大学齐鲁医院 Bace2作为胶质瘤预后/诊断/治疗标志物的应用
WO2022199682A1 (zh) * 2021-03-26 2022-09-29 广州市妇女儿童医疗中心 先天性巨结肠的诊断或早期诊断标志物及其应用

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AU2016377701B2 (en) 2023-04-06
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IL260214A (en) 2018-07-31
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