CN108699019B - 用于治疗中枢神经系统和其他疾病的苯并呋喃衍生物 - Google Patents

用于治疗中枢神经系统和其他疾病的苯并呋喃衍生物 Download PDF

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CN108699019B
CN108699019B CN201680078656.2A CN201680078656A CN108699019B CN 108699019 B CN108699019 B CN 108699019B CN 201680078656 A CN201680078656 A CN 201680078656A CN 108699019 B CN108699019 B CN 108699019B
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acid
compound
benzofuran
phenyl
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CN108699019A (zh
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J.C.华纳
S.R.切鲁库
J.A.格拉丁
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Warner Babcock Institute for Green Chemistry LLC
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    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
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    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical

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CN201680078656.2A 2015-11-11 2016-11-10 用于治疗中枢神经系统和其他疾病的苯并呋喃衍生物 Active CN108699019B (zh)

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US201562253903P 2015-11-11 2015-11-11
US62/253903 2015-11-11
PCT/US2016/061281 WO2017083488A1 (en) 2015-11-11 2016-11-10 Benzofuran derivatives for the treatment of cns and other disorders

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CN108699019B true CN108699019B (zh) 2022-05-10

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US (1) US10590100B2 (enExample)
EP (1) EP3374354B1 (enExample)
JP (1) JP6908805B2 (enExample)
CN (1) CN108699019B (enExample)
AU (1) AU2016353004B2 (enExample)
CA (1) CA3005212C (enExample)
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WO2018208712A1 (en) 2017-05-09 2018-11-15 Warner Babcock Insitute For Green Chemistry, Llc Stilbene and fused stilbene derivatives as solar cell dyes
CN108191966B (zh) * 2018-01-11 2020-10-27 桂林医学院 一种含导肽可穿越血脑屏障螯合脑内铁降自由基的多肽
EP3820465B1 (en) * 2018-07-10 2025-09-17 Ambient Photonics, Inc. Solar cell dyes for copper redox based dye sensitized solar cells and combinations thereof
TWI824012B (zh) * 2019-09-20 2023-12-01 美商安畢特光學公司 用於基於銅氧化還原的染料敏化太陽能電池的太陽能電池染料及其組合
WO2026055841A1 (zh) * 2024-09-11 2026-03-19 凯思凯迪(上海)医药科技股份有限公司 芳环并杂环类化合物、其制备方法和其应用

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IL259674B (en) 2021-07-29
US10590100B2 (en) 2020-03-17
EP3374354B1 (en) 2022-09-28
IL259674A (en) 2018-07-31
JP6908805B2 (ja) 2021-07-28
CN108699019A (zh) 2018-10-23
EP3374354A1 (en) 2018-09-19
CA3005212C (en) 2024-01-23
WO2017083488A1 (en) 2017-05-18
AU2016353004B2 (en) 2020-11-05
EP3374354A4 (en) 2019-07-17
AU2016353004A1 (en) 2018-06-14
CA3005212A1 (en) 2017-05-18
US20180346433A1 (en) 2018-12-06

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