CN108685728A - A kind of eye cream and preparation method thereof - Google Patents

A kind of eye cream and preparation method thereof Download PDF

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Publication number
CN108685728A
CN108685728A CN201810705308.4A CN201810705308A CN108685728A CN 108685728 A CN108685728 A CN 108685728A CN 201810705308 A CN201810705308 A CN 201810705308A CN 108685728 A CN108685728 A CN 108685728A
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extract
eye cream
phase
alcohol
oil
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王齐
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Kunming University of Science and Technology
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Kunming University of Science and Technology
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/347Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9706Algae
    • A61K8/9711Phaeophycota or Phaeophyta [brown algae], e.g. Fucus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
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  • Microbiology (AREA)
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  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a kind of eye creams and preparation method thereof, the eye cream include camellia flower extract, prinsepia utilis royle oil, cannabidiol, cocoyl glucoside and lauric alcohol, thorn A Gan trees benevolence oil, purslane extract, ascorbic acid glucoside, fibroin, aloe barbadensis Miller leaf extract, moral skin repair, Chondrus crispus extract, Japanese elm root extract, fragrant quick easypro, propylben, glycyrrhiza glabra root extract isoreactivity ingredient, remaining is matrix agent, and each ingredient is made after the mixing that gradually feeds intake at different temperatures.Eye cream of the present invention can improve absorption of the human skin to its active ingredient, the effect of realizing the nursing of releiving to eye part skin, desalinate microgroove, anti-oxidant reparation, slow down aging.

Description

A kind of eye cream and preparation method thereof
Technical field
The invention belongs to cosmetic fields, and in particular to a kind of eye cream and preparation method thereof.
Background technology
Skin is the maximum organ of human body, and with advancing age, human body has a series of biology in aging course Change, while the reduction of skin and subcutaneous tissue cell ingredient and the change of immune system.Skin aging mechanism study shows to disappear Except free radical, improve immune function and adjust endocrine function can effective delaying skin tissue aging.
In human facial skin, eye skin is the most thin skin of human body, while being the most frequent position of activity again, pulls skin The most place of skin number.During skin aging, the generation of wrinkle and microgroove is main surface.Therefore, it is badly in need of The eye cream of moisturizing, anti-aging antiallergic sense is moistened in exploitation.And commercially available existing eye cream is pure chemistry constituent mostly, only moisturizing work( Effect.
Invention content
In view of the defects existing in the prior art, the present invention is from the medicinal efficacy of natural products, provide a kind of eye cream and Preparation method removes free radical, improves immune function and adjust endocrine function, to delay eye part skin aging, eliminates Wrinkle and microgroove improve absorption of the human skin to its active ingredient, realize nursing of releiving to eye part skin, desalination microgroove, The effect of anti-oxidant reparation, anti-aging.
The invention is realized by the following technical scheme:
A kind of eye cream, including following ingredient(Weight percent):A phases:Purified water 39.32-73.58%, natrium adetate 0.05%, Card wave U20 0.10%, allantoin 0.20%, xanthans 0.10-0.50%, glycerine 5.00%, camellia flower extract 0.10-0.50%, B Phase:Sucrose Polystearic Acid Esters 1.00-3.00%, vitamin E 0.50-2.00%, dimethyl silicone polymer 3.00%, cetanol 0.10%, tridecanol trimellitate 1.00-3.00%, prinsepia utilis royle oil 0.10-0.20%, dimethyl silicone polymer 3.00%, day Right fatty alcohol(Hexadeca-octadecyl alcohol, the hexadeca-octadecyl alcohol include hexadecanol, heptadecanol and octadecyl alcolol)0.50-0.80%, diethyl Base hexyl hexamethylene 2.00%, cannabidiol 0.50-2.00%, cocoyl glucoside and lauric alcohol 0.50-2.5%, thorn A Gan tree benevolence Oily 0.50-2.5%, C phase:Acrylamide/ammonium acrylate copolymer and polyisobutene and polysorbate -20 0.80%, D phases:Benzene Oxyethanol and Sensiva SC50 compound ligand 0.50%, 1,2- pentanediols 3.00%, hyaluronic acid(10000 molecular weight)0.05- 0.10%, low-numerator sodium hyaluronate(200000 molecular weight)0.01-0.03%, beta glucan 1.00-5.00%, hexyl decyl alcohol and red Bisabol and cetyl-PG hydroxyethyl palmitamides and stearic acid and campesterol class 1.00-3.00%, purslane extract 1.00-5.00%, hydrolysis chitin 0.50-2.00%, ascorbic acid glucoside 0.50-1.00%, fibroin 1.00-3.00%, Aloe barbadensis Miller leaf extract 1.00-3.00%, moral skin repair 0.50-1.00%, Chondrus crispus extract 0.50-1.00%, Japanese elm Root extract 0.50-1.00%, fragrant quick easypro 0.10-0.50%, propylben 0.20%, glycyrrhiza glabra root extract 0.01- 0.10%。
Preferably, the eye cream includes following ingredient(Weight percent):A phases:Purified water 56.60%, natrium adetate 0.05%, card wave U20 0.10%, allantoin 0.20%, xanthans 0.20%, glycerine 5.00%, camellia flower extract 0.10%, B phases: Sucrose Polystearic Acid Esters 2.00%, vitamin e1 .50%, dimethyl silicone polymer 3.00%, cetanol 0.10%, the inclined benzene of tridecanol Three acid esters 2.0%, prinsepia utilis royle oil 0.15%, dimethyl silicone polymer 3.00%, natural fatty alcohol(Hexadeca-octadecyl alcohol, described 16- Octadecyl alcolol includes hexadecanol, heptadecanol and octadecyl alcolol)0.65%, diethylhexyl hexamethylene 2.00%, cannabidiol 1.50%, coconut palm Oil base glucoside and lauric alcohol 1.5%, thorn A Gan tree benevolence oil 1.0%, C phases:Acrylamide/ammonium acrylate copolymer and polyisobutene With polysorbate -20 0.80%, D phases:Phenoxyethanol and Sensiva SC50 compound ligand 0.50%, 1,2- pentanediols 3.00%, Hyaluronic acid(10000 molecular weight)0.08%, low-numerator sodium hyaluronate(200000 molecular weight)0.02%, beta glucan 3.00%, hexyl Decyl alcohol and bisabolol and cetyl-PG hydroxyethyl palmitamides and stearic acid and campesterol class 2.00%, purslane extract 3.00%, chitin 1.50%, ascorbic acid glucoside 1.00%, fibroin 1.00%, aloe barbadensis Miller leaf extract are hydrolyzed 1.00%, moral skin repaiies 0.50%, Chondrus crispus extract 1.00%, Japanese elm root extract 0.50%, the fragrant quick 0.20%, nipalgin that relaxes Propyl ester 0.20%, glycyrrhiza glabra root extract 0.05%.
The preparation method of the eye cream, includes the following steps:
(1)It takes the A phase materials of formula ratio to be added in water phase pot, after being heated to 75-80 DEG C, stirs evenly, be pumped into vacuum emulsifying machine In, heat preservation is spare;
(2)It takes the B phase materials of formula ratio to be added in oil phase pot, after being heated to 80-85 DEG C, stirs evenly, be pumped into vacuum emulsifying machine In;
(3)Vacuum emulsifying machine, emulsifying 15-20min are opened, C phase materials are added in 80-85 DEG C of process control temp, continue equal After matter emulsifies 5-10min, start to cool down;
(4)45 DEG C are cooled to, D phase materials are added, continues to stir 35-40min;
(5)It is cooled to 35 DEG C, you can discharging, inspection after the assay was approved can be filling.
The invention has the advantages that:
(1)Cannabidiol can repair nerve system of human body, and with anti-spasm, resisting rheumatoid arthritis, antianxiety, antidepression, The pharmacological activity such as anti-insomnia, can releive skin after skin takes in human body, it is often more important that have and relieve stress, improve and sleep Dormancy quality adjusts the effect of immunity so that improve skin quality from inside to outside;
(2)Being rich in purslane extract has a large amount of flavonoids, adrenin, polysaccharide and various vitamins, amino acid Equal substances can effectively inhibit pruitus, redness, pain effect, and prevent skin allergy to a certain extent;
(3)Fibroin is the natural polymer fibrin extracted from silk, contains 18 kinds of amino acid;It is to tyrosinase Inhibiting effect, can effectively inhibit the generation of melanin, have the function that skin whitening;In addition, fibroin can also promote Into collagen synthesis, activating skin cell improves microcirculation, the effect of repairing impaired skin histology, reach anti-ageing smoothing wrinkle;
(4)Camellia flower extract is extracted to Yunnan camellia, wherein containing there are many flavones, polyphenol, Tea Saponin class activity constituents. Addition has moistening skin-care, anti-aging, anti-inflammatory and white-skinned face function in cosmetics;
(5)Contain leaf Cai containing reed glucoside, isobarbaloin, β-barbaloin, aloe-emodin and aloe in aloe barbadensis Miller leaf extract Glucoside A, B isoreactivity constituent.Addition aloe barbadensis Miller leaf extract, which has skin histology, in eye cream significantly sterilizes, disappears Inflammation, antiallergy, softening skin effect, and have strong absorption to ultraviolet light, there is sun-proof function;
(6)Chondrus crispus is a kind of natural seaweed, and principle active component is polysaccharide carrageenan in extract, is had to skin The effect of removing aging cutin, Firm, moistening and desalinate wrinkle;
(7)Glycyrrhiza glabra root extract is extracted to the stem of glycyrrhiza glabra, and glycyrrhiza glabra extract can go deep into inside skin and keep High activity effectively inhibits the activity of a variety of enzymes during melanin production, be it is a kind of it is fast, efficient, safe, green it is sun-proof, Whitening cosmetics additive.Glycyrrhiza glabra extract also has effects that prevent pachylosis and anti-inflammatory, antibacterial simultaneously;
(8)By the synergistic effect of the above natural extracts, it can reach and remove free radical, improve immune function and adjusting Endocrine function delays eye part skin aging, smoothes away wrinkles and microgroove.
Specific implementation mode
With reference to embodiment, the claim of the present invention is further described in detail, but not structure At any limitation of the invention, anyone limited number of time made within the scope of the invention as claimed modification, still in the present invention Claims in.
Embodiment 1
A kind of eye cream, including following ingredient(Weight percent):A phases:Purified water 56.60%, natrium adetate 0.05%, card wave U20 0.10%, allantoin 0.20%, xanthans 0.20%, glycerine 5.00%, camellia flower extract(The limited public affairs of Shan Yunnan, Yunnan medicine company Department)0.10%, B phase:Sucrose Polystearic Acid Esters 2.00%, vitamin e1 .50%, dimethyl silicone polymer 3.00%, cetanol 0.10%, tridecanol trimellitate 2.0%, prinsepia utilis royle oil 0.15%, dimethyl silicone polymer 3.00%, natural fatty alcohol(Ten Six-octadecyl alcolols)0.65%, diethylhexyl hexamethylene 2.00%, cannabidiol 1.50%, cocoyl glucoside and lauric alcohol 1.5%, The dry tree benevolence oil of Ci A(French SEPPIC companies)1.0%, C phase:Acrylamide/ammonium acrylate copolymer and polyisobutene and poly- mountain Pears alcohol ester -20(French SEPPIC companies)0.80%, D phase:Phenoxyethanol and Sensiva SC50 compound ligand(Kening Co., Ltd of the U.S.) 0.50%, 1,2- pentanediols 3.00%, hyaluronic acid(10000 molecular weight)0.08%, low-numerator sodium hyaluronate(200000 molecular weight) 0.02%, beta glucan 3.00%, hexyl decyl alcohol and bisabolol and cetyl-PG hydroxyethyl palmitamides and stearic acid and rape Sterols(German SYMRISE companies)2.00%, purslane extract(Bioland companies of South Korea)3.00%, chitin is hydrolyzed(North Capital and the bio tech ltd Zheng Tang)1.50%, ascorbic acid glucoside 1.00%, fibroin 1.00%, Aloe Barbadensis Miller Extract 1.00%, moral skin repair 0.50%, Chondrus crispus extract 1.00%, Japanese elm root extract(Bioland companies of South Korea) 0.50%, fragrant quick 0.20%, propylben 0.20%, the glycyrrhiza glabra root extract 0.05% of relaxing.
The preparation method of the eye cream is:
(1)It takes the A phase materials of formula ratio to be added in water phase pot, after being heated to 75 DEG C, stirs evenly, be pumped into vacuum emulsifying machine, It keeps the temperature spare;
(2)It takes the B phase materials of formula ratio to be added in oil phase pot, after being heated to 80 DEG C, stirs evenly, be pumped into vacuum emulsifying machine;
(3)Vacuum emulsifying machine, emulsifying 15min are opened, C phase materials are added in 80 DEG C of process control temp, continue emulsifying After 5min, start to cool down;
(4)45 DEG C are cooled to, D phase materials are added, continues to stir 35min;
(5)It is cooled to 35 DEG C, you can discharging, inspection after the assay was approved can be filling.
Embodiment 2
A kind of eye cream, including following ingredient(Weight percent):A phases:Purified water 39.32%, natrium adetate 0.05%, card wave U20 0.10%, allantoin 0.20%, xanthans 0.50%, glycerine 5.00%, camellia flower extract(The limited public affairs of Shan Yunnan, Yunnan medicine company Department)0.50%, B phase:Sucrose Polystearic Acid Esters 3.00%, vitamin E 2.00%, dimethyl silicone polymer 3.00%, cetanol 0.10%, tridecanol trimellitate 3.00%, prinsepia utilis royle oil 0.20%, dimethyl silicone polymer 3.00%, natural fatty alcohol(Ten Six-octadecyl alcolols)0.80%, diethylhexyl hexamethylene 2.00%, cannabidiol 2.00%, cocoyl glucoside and lauric alcohol 2.5%, The dry tree benevolence oil of Ci A(French SEPPIC companies)2.5%, C phase:Acrylamide/ammonium acrylate copolymer and polyisobutene and poly- mountain Pears alcohol ester -20(French SEPPIC companies)0.80%, D phase:Phenoxyethanol and Sensiva SC50 compound ligand(Kening Co., Ltd of the U.S.) 0.50%, 1,2- pentanediols 3.00%, hyaluronic acid(10000 molecular weight)0.10%, low-numerator sodium hyaluronate(200000 molecular weight) 0.03%, beta glucan 5.00%, hexyl decyl alcohol and bisabolol and cetyl-PG hydroxyethyl palmitamides and stearic acid and rape Sterols(German SYMRISE companies)3.00%, purslane extract(Bioland companies of South Korea)5.00%, chitin is hydrolyzed(North Capital and the bio tech ltd Zheng Tang)2.00%, ascorbic acid glucoside 1.00%, fibroin 3.00%, Aloe Barbadensis Miller Extract 3.00%, moral skin repair 1.00%, Chondrus crispus extract 1.00%, Japanese elm root extract(Bioland companies of South Korea) 1.00%, fragrant quick 0.50%, propylben 0.20%, the glycyrrhiza glabra root extract 0.10% of relaxing.
The preparation method of the eye cream is:
(1)It takes the A phase materials of formula ratio to be added in water phase pot, after being heated to 80 DEG C, stirs evenly, be pumped into vacuum emulsifying machine, It keeps the temperature spare;
(2)It takes the B phase materials of formula ratio to be added in oil phase pot, after being heated to 85 DEG C, stirs evenly, be pumped into vacuum emulsifying machine;
(3)Vacuum emulsifying machine, emulsifying 20min are opened, C phase materials are added in 85 DEG C of process control temp, continue emulsifying After 10min, start to cool down;
(4)45 DEG C are cooled to, D phase materials are added, continues to stir 40min;
(5)It is cooled to 35 DEG C, you can discharging, inspection after the assay was approved can be filling.
Embodiment 3
A kind of eye cream, including following ingredient(Weight percent):A phases:Purified water 73.58%, natrium adetate 0.05%, card wave U20 0.10%, allantoin 0.20%, xanthans 0.10%, glycerine 5.00%, camellia flower extract(The limited public affairs of Shan Yunnan, Yunnan medicine company Department)0.10%, B phase:Sucrose Polystearic Acid Esters 1.00%, vitamin E 0.50%, dimethyl silicone polymer 3.00%, cetanol 0.10%, tridecanol trimellitate 1.00%, prinsepia utilis royle oil 0.10%, dimethyl silicone polymer 3.00%, natural fatty alcohol(Ten Six-octadecyl alcolols)0.50%, diethylhexyl hexamethylene 2.00%, cannabidiol 0.50%, cocoyl glucoside and lauric alcohol 0.50%, thorn A Gan trees benevolence oil(French SEPPIC companies)0.50%, C phase:Acrylamide/ammonium acrylate copolymer and polyisobutene With polysorbate -20(French SEPPIC companies)0.80%, D phase:Phenoxyethanol and Sensiva SC50 compound ligand(Section of the U.S. Ning companies)0.50%, 1,2- pentanediols 3.00%, hyaluronic acid(10000 molecular weight)0.05%, low-numerator sodium hyaluronate(20 very much Son amount)0.01%, beta glucan 1.00%, hexyl decyl alcohol and bisabolol and cetyl-PG hydroxyethyl palmitamides and stearic acid With campesterol class(German SYMRISE companies)1.00%, purslane extract(Bioland companies of South Korea)1.00%, shell is hydrolyzed Polysaccharide(Beijing and the bio tech ltd Zheng Tang)0.50%, ascorbic acid glucoside 0.50%, fibroin 1.00-3.00%, Aloe barbadensis Miller leaf extract 1.00%, moral skin repair 0.50%, Chondrus crispus extract 0.50%, Japanese elm root extract(South Korea Bioland companies)0.50%, fragrant quick 0.10%, propylben 0.20%, the glycyrrhiza glabra root extract 0.01% of relaxing.
The preparation method of the eye cream is:
(1)It takes the A phase materials of formula ratio to be added in water phase pot, after being heated to 75 DEG C, stirs evenly, be pumped into vacuum emulsifying machine, It keeps the temperature spare;
(2)It takes the B phase materials of formula ratio to be added in oil phase pot, after being heated to 80 DEG C, stirs evenly, be pumped into vacuum emulsifying machine;
(3)Vacuum emulsifying machine, emulsifying 20min are opened, C phase materials are added in 80 DEG C of process control temp, continue emulsifying After 5min, start to cool down;
(4)45 DEG C are cooled to, D phase materials are added, continues to stir 35min;
(5)It is cooled to 35 DEG C, you can discharging, inspection after the assay was approved can be filling.
Both effectiveness experiment:
The measurement of oxidation resistance
Free radical is normal biochemical reaction product in biological normal metabolic processes, under normal conditions, machine interior free yl Result from elimination in a kind of dynamic balance, when organism is weaker than generative capacity to the elimination ability of free radical, meeting The normal cell of human body, including skin cleaning are caused to damage, accelerate organ senescence.Active ingredient is to free radical in skin-protection product Scavenging activity be its important indicator.
It selects DPPH methods to test the external model of radicals scavenging, the absorption peak intensity of 517nm is measured with spectrophotometry Degree variation, to the oxidation resistance more of the invention with commercially available reference substance.
It chooses two kinds of imports, a kind of domestic production similar product and the present invention and does check experiment, specific test method is as follows:
20mg DPPH are weighed, with absolute ethyl alcohol constant volume in 250mL brown volumetric flasks, obtain the DPPH solution of 80 μ g/mL;
Tri- kinds of reference substances of 0.50g and eye cream of the present invention are accurately weighed respectively, are dissolved with absolute ethyl alcohol, and be quantitatively transferred to 50mL capacity It is quantitative to scale, as reference substance and test solution solution of the present invention with absolute ethyl alcohol in bottle;
In 10mL colorimetric cylinders ethyl alcohol be added 5.0mL DPPH solution, after be separately added into reference substance and test solution solution of the present invention, then It is settled to scale with absolute ethyl alcohol, absorbance is surveyed at 517nm wavelength with 1.0cm colorimetric cylinders immediately after mixing, is denoted as Ai, then Room temperature measures absorbance after 30min is kept in dark place, and is denoted as Aj.Individually take 5.0mL DPPH solution with anhydrous in 10mL colorimetric cylinders Ethyl alcohol is settled to scale, measures 517nm absorbances, is denoted as Ac.Free radical scavenging activity is calculated as follows(K):
K(%)=[1-(Ai-Aj)/Ac]*100%
In triplicate, take its average value as final result.
The experimental results showed that the present invention is under 0.50g sampling amounts, the clearance rate to free radical is 31.7%, higher than it is commercially available into Mouthful(28.4% and 1.3%)With it is domestic(20.7%)Reference substance illustrates that this product oxidation resistance is higher than existing commercial product.

Claims (6)

1. a kind of eye cream, including following ingredient, the weight percent of each ingredient are:A phases:Purified water 39.32-73.58%, according to ground Acid disodium 0.05%, card wave U20 0.10%, allantoin 0.20%, xanthans 0.10-0.50%, glycerine 5.00%, camellia flower extract 0.10-0.50%, B phase:Sucrose Polystearic Acid Esters 1.00-3.00%, vitamin E 0.50-2.00%, dimethyl silicone polymer 3.00%, cetanol 0.10%, tridecanol trimellitate 1.00-3.00%, prinsepia utilis royle oil 0.10-0.20%, poly dimethyl silicon Oxygen alkane 3.00%, natural fatty alcohol 0.50-0.80%, diethylhexyl hexamethylene 2.00%, cannabidiol 0.50-2.00%, cocounut oil Base glucoside and lauric alcohol 0.50-2.5%, thorn A Gan tree benevolence oil 0.50-2.5%, C phases:Acrylamide/ammonium acrylate copolymer and Polyisobutene and polysorbate -20 0.80%, D phases:Phenoxyethanol and Sensiva SC50 compound ligand 0.50%, 1,2- penta 2 Alcohol 3.00%, hyaluronic acid 0.05-0.10%, low-numerator sodium hyaluronate 0.01-0.03%, beta glucan 1.00-5.00%, hexyl Decyl alcohol and bisabolol and cetyl-PG hydroxyethyl palmitamides and stearic acid and campesterol class 1.00-3.00%, purslane Extract 1.00-5.00%, hydrolysis chitin 0.50-2.00%, ascorbic acid glucoside 0.50-1.00%, fibroin 1.00- 3.00%, aloe barbadensis Miller leaf extract 1.00-3.00%, moral skin repair 0.50-1.00%, Chondrus crispus extract 0.50- 1.00%, Japanese elm root extract 0.50-1.00%, fragrant quick easypro 0.10-0.50%, propylben 0.20%, the extraction of glycyrrhiza glabra root Object 0.01-0.10%.
2. eye cream according to claim 1, which is characterized in that including following ingredient, the weight percent of each ingredient is:A Phase:Purified water 56.60%, natrium adetate 0.05%, card wave U20 0.10%, allantoin 0.20%, xanthans 0.20%, glycerine 5.00%, camellia flower extract 0.10%, B phases:Sucrose Polystearic Acid Esters 2.00%, vitamin e1 .50%, dimethyl silicone polymer 3.00%, cetanol 0.10%, tridecanol trimellitate 2.0%, prinsepia utilis royle oil 0.15%, dimethyl silicone polymer 3.00%, day Right fatty alcohol 0.65%, diethylhexyl hexamethylene 2.00%, cannabidiol 1.50%, cocoyl glucoside and lauric alcohol 1.5%, thorn A Gan tree benevolence oil 1.0%, C phases:Acrylamide/ammonium acrylate copolymer and polyisobutene and polysorbate -20 0.80%, D Phase:Phenoxyethanol and Sensiva SC50 compound ligand 0.50%, 1,2- pentanediols 3.00%, hyaluronic acid 0.08%, low molecule are transparent Matter acid sodium 0.02%, beta glucan 3.00%, hexyl decyl alcohol and bisabolol and cetyl-PG hydroxyethyl palmitamides and stearic acid With campesterol class 2.00%, purslane extract 3.00%, hydrolysis chitin 1.50%, ascorbic acid glucoside 1.00%, silk Albumen 1.00%, aloe barbadensis Miller leaf extract 1.00%, moral skin repair 0.50%, Chondrus crispus extract 1.00%, Japanese elm root carries Take object 0.50%, fragrant quick 0.20%, propylben 0.20%, the glycyrrhiza glabra root extract 0.05% of relaxing.
3. eye cream according to claim 1 or 2, which is characterized in that the natural fatty alcohol is hexadeca-octadecyl alcohol.
4. eye cream according to claim 1 or 2, which is characterized in that the hyaluronic acid is 10,000 molecular weight.
5. eye cream according to claim 1 or 2, which is characterized in that low-numerator sodium hyaluronate is 200,000 molecular weight.
6. the preparation method of eye cream, includes the following steps described in claim 1-5 any one:
(1)It takes A phase materials to be added in water phase pot, after being heated to 75-80 DEG C, stirs evenly, be pumped into vacuum emulsifying machine, heat preservation is standby With;
(2)It takes B phase materials to be added in oil phase pot, after being heated to 80-85 DEG C, stirs evenly, be pumped into vacuum emulsifying machine;
(3)Vacuum emulsifying machine, emulsifying 15-20min are opened, C phase materials are added in 80-85 DEG C of process control temp, continue equal After matter emulsifies 5-10min, start to cool down;
(4)45 DEG C are cooled to, D phase materials are added, continues to stir 35-40min;
(5)Be cooled to 35 DEG C to get.
CN201810705308.4A 2018-07-02 2018-07-02 A kind of eye cream and preparation method thereof Pending CN108685728A (en)

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Application publication date: 20181023