CN115089536A - Moisturizing cream with anti-aging effect strengthening effect and preparation method thereof - Google Patents
Moisturizing cream with anti-aging effect strengthening effect and preparation method thereof Download PDFInfo
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Abstract
The invention discloses moisturizing cream for strengthening anti-aging effect and a preparation method thereof, and the moisturizing cream comprises lycium ruthenicum raw stock, magnetite pentaaviti N, cell activating factor OXY229PF, gene repair beauty extract GENEWHITE-D60, double purple oil, cucumber water, pomegranate fruit extract, yeast/barley seed fermentation product filtrate, ginseng root extract, perilla seed extract, wenzhou mandarin orange peel extract, soapberry fruit extract, tara gum, carrageen rup extract, austenitic seaweed extract, vaccinum myrtillus fruit juice and vaccinum myrtillus fruit extract, wild soybean oil, peony root extract, pine mushroom extract, harpagne, pseudo-agar extract, purslane extract, caffeine, sunflower seed oil, p-hydroxyacetophenone and sodium hyaluronate. The invention ensures that the face cream has good moisturizing effect, further strengthens anti-aging effect, and can effectively brighten and whiten skin, improve false fine lines of skin and reduce true wrinkles.
Description
Technical Field
The invention relates to a moisturizing cream with an enhanced anti-aging effect and a preparation method thereof, in particular to a moisturizing cream containing a moisturizing component, an antioxidant and anti-saccharification component, an activated cell regeneration component and an anti-allergy component and a preparation method thereof.
Background
With age, the skin tissue function of the human body is slowly decaying.
Along with the improvement of living standard of people, the demand of anti-aging skin care products is continuously released, and a plurality of skin care products with anti-aging efficacy are continuously produced in the market. The anti-aging skin care products usually exist in the form of essential oil or essence, the main function of the cream is usually to preserve moisture, and other effects such as anti-aging, whitening, freckle removing and the like are realized by the essential products. The cream product disclosed by the invention has the advantages that the moisturizing effect of the cream product is further enhanced through comprehensive matching and application of multiple components, and the anti-aging effect of the cream product is further enhanced while the moisturizing effect is enhanced, so that the cream product can be used as an independent anti-aging product.
Disclosure of Invention
The technical problem to be solved by the invention is to provide the moisturizing cream with the anti-aging effect strengthened and the preparation method thereof, and the moisturizing component and the anti-aging component are comprehensively applied, so that the anti-aging effect of the cream is strengthened while the moisturizing effect of the cream is maintained, and the cream product not only has a good moisturizing effect, but also has a good anti-aging effect, so that the cream product can be used as an independent anti-aging product.
In order to solve the technical problems, the technical scheme adopted by the invention is as follows.
The moisture-preserving cream for strengthening the anti-aging effect comprises the following components in percentage by weight: 1-100% of water; 1-10% of C12-20 acid PEG-8 ester; 0.1-4% of isoprene glycol; 0.1-4% of caprylic/capric triglyceride; 1-10% of hydrogenated polyisobutene; 1-5% of tri (octyldodecanol) citrate; 1-5% of polydimethylsiloxane; 1-5% of phenyl trimethyl siloxane; 0.1-5% of sunflower seed oil; 0.1-5% of cucumber juice; 0.1-5% of ginseng root extract; 0.1-5% of citrus unshiu peel extract; 0.1-5% of soapberry fruit extract; 0.1-5% of Caesalpinia spinosa gum; 0.1-5% of pomegranate fruit extract; 0.1 to 5 percent of caffeine; 0.1-5% of Chondrus crispus extract; 0.1-5% of an austenitic seaweed extract; 0.1 to 5 percent of vaccinium myrtillus juice; 0.1-5% of vaccinium myrtillus fruit extract; 0.1-5% of acetyl chitosamine; 0.1-5% of yeast extract; 0.1-5% of peony root extract; 0.1-1% of sodium hyaluronate; 0.1-5% of ergothioneine; 0.1-5% of Armillaria matsutake extract; 0.1-5% of 1, 2-pentanediol; 0.1-5% of ethylhexyl glycerin; 0.1-5% of tetrahexyldecyl ascorbate; 0.1-5% of wild soybean oil; 0.1-5% of a Uncaria tomentosa extract; 0.1-5% of a broccoli extract; 0.1-5% of purslane extract; 0.1-5% of yeast fermentation product extract; 0.1-5% of tocopherol acetate; 0.1-5% of potassium cetyl phosphate; 0.1-5% of cetearyl alcohol; inulin lauryl carbamate 0.1-5%; 0.1-5% of lecithin; 0.1-5% of siloxane triol alginate; 0.1-5% of oleic acid; 0.1-5% of sorbitol (sugar); 0.1-5% of glycerol; 0.1-5% of butanediol; 0.1-5% of propylene glycol; 0.1-5% of acryloyl dimethyl ammonium taurate/VP copolymer; 0.1-5% of xanthan gum; 0.01-1% of p-hydroxyacetophenone; 0.01-1% of EDTA disodium; 0.1-1% of sodium citrate; 1-5% of yeast/barley seed fermentation product filtrate; the water-locking magnet PentaavitiN 1-10%; 3-10% of lycium ruthenicum raw stock; OXY229PF0.2-5% of cell activating factor; gene repair Mei Jing GENEWHITE-D600.2-5%; 0.1-5% of double purple oil.
Further, the water-locking magnet Pentaavitin comprises saccharide isomers and deionized water. The saccharide isomerate is a natural humectant extracted from a sucrose complex, and achieves a moisturizing effect by assisting water to combine with keratin in the horny layer. The contained plant D-glucose can supplement water strongly, improve the water retention capacity of skin and strengthen the barrier function.
Furthermore, the lycium ruthenicum raw stock contains lycium ruthenicum extract and lactic acid bacteria fermentation products, is a plant active ingredient extracted by a microbial fermentation method, contains lycium ruthenicum polysaccharide, betaine, physalin, anthocyanin, carotene, B vitamins, vitamin C, linoleic acid and other active ingredients, the lycium ruthenicum polysaccharide is a main anti-aging active ingredient of lycium ruthenicum, and the lycium ruthenicum polysaccharide obtained by fermenting the lactic acid bacteria has small molecular weight and is easier to be absorbed through skin, can keep the skin of a human body to be smooth and exquisite, prevents wrinkles and has a good anti-aging effect.
Further, the cell activating factor OXY229PF comprises deionized water, glycerol, yeast lysate, valine, threonine, glycine, and glutamic acid. Is obtained by adopting biotechnology in aerobic environment, is non-animal, contains effective components capable of improving metabolism condition of 'aged skin cells', and activates cell renewal and living tissue regeneration.
Further, the gene repair extract GENEWHITE-D60 comprises Vitex agnus-castus extract, herba Hedyotidis Diffusae extract and calendula extract. Is prepared by extracting rhizome parts of blue valley lily and negundo chastetree by supercritical fluid extraction process, and synergistically fermenting and extracting effective components of oldenlandia diffusa and calendula officinalis. Adopting the technical principle of gene signal interception, and accurately inhibiting tyrosinase activity and melanin generation from the source; oxidation resistance, inflammation resistance and damaged cell repair; the effects of quickly breaking down pigmentation, brightening skin and lightening color spots are achieved.
Further, the lithospermum oil comprises Sinkiang arnebia root extract, caprylic/capric triglyceride, perilla seed extract, pentaerythritol tetrakis (bis-tert-butyl hydroxyhydrocinnamate); can promote epithelial cell proliferation, accelerate wound healing, and resist allergy and inflammation.
Furthermore, the raw material of the ginseng root extract is from the root hairs of ginseng, the effective components contained in the ginseng root extract are retained by adopting the microbial low-temperature fermentation extraction technology, the ginseng root extract contains various effective components such as ginsenoside, ginseng polysaccharide, bioactive peptide and the like, the content of superoxide dismutase and catalase in blood can be increased, and the ginseng root extract has an antioxidation effect. Partial monomer saponin in ginsenoside can reduce free radical content in vivo to different extent, and also has effects of delaying nerve cell aging, stabilizing cell membrane structure, increasing protein synthesis, delaying skin senilism, and preventing and reducing skin wrinkle. The ginseng active substance contained in the ginseng root extract also has the function of inhibiting the reduction of melanin, makes the skin white and smooth, and is a very ideal whitening component.
Furthermore, the pomegranate fruit extract contains various effective components such as anthocyanin, pomegranate polyphenol, ellagic acid and the like, which are extremely strong antioxidant substances, have high DPPH free radical removal efficiency and can improve the skin oxidation resistance. The punicosides contained in the composition can inhibit the activity of hyaluronidase, thereby slowing down the decomposition speed of hyaluronic acid and achieving the effect of moisturizing. The pomegranate polyphenols can react with protein in skin by hydrogen bond and hydrophobic effect to generate astringent effect, which can tighten skin, reduce wrinkle and delay aging. The pomegranate fruit extract also shows strong inhibition effect on the activity of B-16 melanocyte, and is a good whitening component. Antibacterial tests prove that alcohol extract and peel decoction of pomegranate have broad-spectrum antibacterial effect and obvious inhibitory effect on staphylococcus aureus, hemolytic streptococcus, vibrio cholerae, shigella dysenteriae and the like.
Furthermore, the yeast/barley seed fermentation product filtrate is prepared by fermenting barley seeds serving as a raw material by using yeast, is rich in natural active component substances such as micromolecular amino acid, polypeptide, nucleotide, vitamins and the like, and is a very good comprehensive skin conditioner. The saccharomycete fermentation product filtrate can balance grease, moisten white, lighten spots, resist oxidation and repair skin; the Natural Moisturizing Factor (NMF) is rich in moisture for promoting the full moisture of the horny layer, and is beneficial to the absorption and transformation of nutrient substances. Can effectively improve the water holding capacity of the skin, enter deep body circulation, resist oxidation, reduce skin inflammation, smooth and tender the skin, reduce skin wrinkles, prevent and delay aging and whiten the skin.
Furthermore, the cucumber juice is prepared from cucumbers by a low-temperature extraction technology. It contains bioactive components such as vitamin E and Cucumis sativus enzyme, has effects of activating aromatase in cells, promoting metabolism, removing wrinkle, and resisting aging. And is also a good humectant.
Furthermore, the wenzhou mandarin orange peel extract is prepared by adopting the wenzhou mandarin orange peel produced in the kyushu area as a raw material, and extracting through a low-temperature biological fermentation technology to retain bioactive components. Contains various kinds of sexual substances such as eucalyptol, saccharide, flavone, hesperidin, etc. The flavonoid substance contained in the composition has the effects of scavenging free radicals, resisting inflammation, resisting virus, resisting bacteria, delaying aging, inhibiting sebum synthesis and the like, the hesperidin has a promoting effect on the generation of cerebroamide, and the cerebroamide has very important physiological functions in organisms, so that the composition has a skin-activating effect, and has a very good anti-aging effect by combining the cell proliferation capacity of the cerebroamide. The wenzhou mandarin orange peel extract also has the function of promoting the luciferase activity and has obvious anti-inflammatory effect.
Furthermore, the soapberry fruit extract is a biological fermentation extract of soapberry, contains saponin, vitamin, amino acid, fruit acid and the like, and can help skin to remove aged cutin accumulated on the outer layer, accelerate skin renewal, and improve the problems of skin acne, black spots, wrinkles, dry skin, roughness and the like.
Further, the caffeine is a xanthine alkaloid compound. It is mainly found in the fruits and leaves of coffee tree, tea tree, ilex paraguariensis and guarana, and caffeine mainly acts through antioxidation, anti-inflammation and regulating skin moisture circulation. The product can be used as antioxidant for delaying skin senilism caused by sunshine and pollution, scavenging free radicals harmful to skin, protecting cells from ultraviolet radiation, delaying skin photoaging process, tranquilizing mind, relieving inflammation, improving blood circulation of face and around eyes, relieving eye edema, and reducing eye pouch and dark circle.
Furthermore, the raw material of the austenitic seaweed extract is sourced from Okinawa area of Japan, the extract is a pure natural marine biological product, and the special seaweed contains active ingredients such as alginic acid, crude protein, multiple vitamins, enzymes, trace elements and the like, and has excellent effects of resisting oxidation, delaying senescence and whitening. The antioxidant components and the moisture-retaining components in the austenitic seaweed extract are easily absorbed by skin, and the vitamin C participates in hydroxylation reaction to synthesize collagen, so that collagen is supplemented for the skin, and the antioxidant and wrinkle-removing effects are achieved. The methionine and cystine can regulate water-oil balance of skin, keep moisture and lock water. The contained vitamin E and other ingredients can effectively relieve skin pigmentation, lighten color spots and improve skin quality.
Further, the bilberry fruit extract and the bilberry fruit juice contain many kinds and high content of flavonoids, and mainly contain components equivalent to anthocyanin, anthocyanidin, flavanol, proanthocyanidin, lutein and quercetin. The anthocyanin is a pure natural anti-aging nutritional supplement and is the most effective antioxidant found by people at present. The anthocyanin is fifty times higher than vitamin E and two hundred times higher than vitamin C in oxidation resistance, can enhance the elasticity of skin, strongly resist oxidation and aging, enhance the thickness of skin health barrier and the density of dermis layer, effectively block the formation of melanin and has whitening effect by removing harmful free radicals in vivo. It also has effects in improving hydration, reducing water loss through skin, and improving skin moisture retention. The contained flavonoid compounds also have biological activities of protecting retinal cells, inhibiting angiotensin converting enzyme, resisting oxidative stress of nerve cells and the like, and can relieve or reduce skin inflammation phenomena by inhibiting prostate gland hormone, cytokinin, histidinium, lipoxygenase, cyclooxygenase and the like, thereby having good anti-inflammatory effect.
Furthermore, the peony root extract contains various effective components such as anthocyanin, flavonoid, polyphenol, phytosterol, etc. Scientific experiments prove that the skin care product has stronger antioxidant activity, can remove free radicals in a chain reaction initiation stage, can directly capture the free radicals in a reaction chain, blocks the chain reaction of the free radicals, has double functions of prevention and chain breakage, and has obvious anti-wrinkle and anti-aging effects when being applied to skin care products. The contained paeonol also has analgesic, antipyretic, spasmolytic, and antiinflammatory effects. The peony polysaccharide has effects of inhibiting melanin, preventing melanin generation, increasing skin fineness and improving skin whiteness.
Further, the matsutake mushroom extract is prepared from fruiting body of matsutake mushroom of Tricholomataceae by low temperature fermentation extraction technique to retain bioactive components. The Armillaria matsutake extract contains 18 amino acids, 49 active nutrients, unsaturated fatty acids, vitamins, and various active enzymes. In addition, the mushroom fungus also contains 3 kinds of precious active substances, namely double-chain tricholoma matsutake polysaccharide, tricholoma matsutake polypeptide and unique anti-cancer substance-tricholoma matsutake alcohol all over the world, and is the most precious natural medicinal fungus all over the world. The matsutake mushroom extract contains triterpenes: the tricholoma matsutake triterpene has the effect of inhibiting tyrosinase activity, intervenes in the generation process of melanin deposition, has the effects of beautifying and whitening when used for protecting skin, and is an ideal raw material of whitening and anti-aging cosmetics. The active substance can enhance skin immunity by enhancing monocyte macrophage system function, and has effects of inhibiting cell division and regulating immune system reaction, and good antiviral effect.
Furthermore, the wild soybean oil contains rich nutrient substances such as isoflavone, fatty acid, vitamin and the like, and can help strengthen skin barrier, make loose skin more compact and improve skin elasticity around pores. The wild soybean oil contains rich amino acids, and can nourish skin, relieve skin dryness and roughness, make skin durable, smooth and tender, and soft touch feeling. The linoleic acid contained in the whitening cream can effectively prevent the synthesis of melanin in skin cells, has a good whitening effect, and can effectively improve skin aging. Isoflavone in the wild soybean oil is a chemical component with a structure similar to that of estrogen, is a plant estrogen with estrogen activity, can delay female cell aging and keep skin elastic, and is a natural beautifying and face nourishing raw material.
Further, the purslane extract contains components such as polysaccharide, vitamins, amino acids and the like. The plant polysaccharide and vitamins contained in the composition can nourish the skin, promote the physiological function of epithelial cells to be normal, and reduce the generation of dead skin and cuticle; it can relieve skin and inhibit skin pruritus caused by dryness. Also has obvious inhibition ability on pain and red swelling. The herba Portulacae extract contains flavone and saponin, and has effects of scavenging free radicals, resisting oxidation, and effectively delaying skin aging. The alkaloid and flavone contained in the purslane extract also have good antibacterial and common pathogenic dermatophyte inhibiting effects, and can further protect damaged skin and promote the rapid recovery of local inflammation when being used in skin care products.
Furthermore, the sunflower seed oil is an important base oil raw material and contains nutritional ingredients such as phytosterol, lecithin, oleic acid and the like, and the sunflower seed oil has an activating effect on peroxidase-activated receptors, can stimulate skin lipid synthesis, activates an anti-inflammatory function, promotes skin wound healing and maintains skin barriers. The sunflower seed oil can promote decomposition of fat cells, and has weight reducing effect. Has effects in inhibiting tyrosinase and whitening skin. The oleic acid has good oxidation resistance, and can moisten and soften skin cutin, resist aging, and prevent water loss through skin epidermis.
Furthermore, the C12-20 acid PEG-8 ester, the glycerol and the inulin lauryl carbamate are used as the emulsifier of the formula.
Further, the ammonium acryloyldimethyl taurate/VP copolymer and the xanthan gum are thickening agents of the formula disclosed by the invention.
Furthermore, the p-hydroxyacetophenone is an antioxidant of the formula, and is mainly used for the preservative function.
Further, the disodium EDTA is a chelating agent for the formulation of the present invention.
Further, the sodium citrate is a pH regulator formulated by the present invention for regulating the overall pH of the product.
A preparation method of moisturizing cream with an anti-aging effect is enhanced, and comprises the following steps:
accurately weighing various raw materials for later use;
cleaning an emulsifying pot, mixing the phase A, adding the phase A into an oil phase pot, and heating to 85 ℃;
thirdly, adding the phase B into a water phase pot, heating to 85 ℃, stirring uniformly, and keeping the temperature for half an hour;
pumping the phase A into an emulsifying pot, pumping the phase B into the emulsifying pot, homogenizing, stirring and emulsifying;
cooling to 45 ℃, sequentially adding the C phase components, and uniformly stirring;
sixthly, sampling, measuring pH, discharging after the semi-product sampling detection meets the standard;
and seventhly, after the semi-finished product is inspected to be qualified, filling and packaging, and after the finished product is inspected to be qualified, warehousing.
The phase A comprises: PEG-8C 12-20 acid ester, caprylic/capric triglyceride, hydrogenated polyisobutene, tri (octyldodecanol) citrate, polydimethylsiloxane, phenyl trimethicone, sunflower seed oil, soybean oil, peony root extract, tocopheryl acetate, potassium cetyl phosphate, cetearyl alcohol.
The phase B comprises: deionized water, isoprene glycol, glycerol, inulin lauryl carbamate, acryloyl dimethyl ammonium taurate/VP copolymer, xanthan gum, p-hydroxyacetophenone and EDTA disodium.
The phase C comprises: lycium ruthenicum raw stock, yeast/barley seed fermentation product filtrate, cucumber fruit water, cell activation factor OXY229PF, ginseng root extract, perilla seed extract, wenzhou mandarin orange peel extract, generepair beauty extract GENEWHITE-D60, magnetite pentaviti N, soapberry fruit extract, tara gum, glycerin, propylene glycol, pomegranate fruit extract, caffeine, silicone triol alginate, butylene glycol, carrageen crispa extract, austenitic seaweed extract, bilberry juice, bilberry extract, acetyl chitosamine, yeast extract, sodium hyaluronate, ergothioneine, matsutake mushroom extract, 1, 2-pentanediol, ethylhexylglycerin, tetrahexyldecanol ascorbate, Uncaria tomentosa extract, gelidium amabilis extract, purslane extract, yeast fermentation product extract, lecithin, oleic acid, xanthan gum, sorbitol (sugar) alcohol, glycerin, sodium stearate, sorbitol (sodium stearate), sorbitol) (sodium stearate), sorbitol (sorbitol) (sodium stearate), sorbitol) (sorbitol, Sodium citrate and double purple oil.
The invention completely meets all indexes in the technical Specification for cosmetic safety (2022 edition) issued by the state, and the face cream product does not contain any toxic substance.
Due to the adoption of the technical scheme, the technical progress of the invention is as follows.
According to the invention, by adding various combined components such as lycium ruthenicum raw stock, yeast/barley seed fermentation product filtrate, cucumber fruit juice, cell activating factors OXY229PF, ginseng root extract, perilla seed extract, wenzhou mandarin orange peel extract, gene repairing beauty extract GENEWHITE-D60, and crystal locking magnet Pentaavitin into the formula of the cream, the anti-aging effect of the cream is enhanced while the moisturizing effect of the cream is maintained, so that the cream product not only has a good moisturizing effect, but also has a good anti-aging effect, and the cream product can be used independently as an independent anti-aging product.
According to the invention, through the comprehensive application of sodium hyaluronate and the locked magnet Pentaavitin, the face cream has a good moisturizing effect, and meanwhile, through the comprehensive application of cell activating factor OXY229PF and gene signal blocking technical component gene repairing beauty extract GENEWHITE-D60, the metabolism condition of aged skin cells is improved, the cells are activated to be updated, damaged cells are quickly repaired, and the regeneration of skin tissues is activated. The lycium ruthenicum raw pulp, the pomegranate fruit extract, the ginseng root extract, the saccharomycetes/barley seed fermentation product filtrate, the double violet oil and the like extracted by a microbial fermentation method further enhance the oxidation resistance and the anti-saccharification capacity of skin cells, quickly remove free radicals, tighten and resist wrinkles, brighten and whiten the skin, fade color spots and delay aging.
Drawings
FIG. 1 is a graph illustrating the effectiveness of a moisture retention test according to an embodiment of the present invention;
FIG. 2 is a graph illustrating the effect of skin smoothness change rate testing according to an embodiment of the present invention;
FIG. 3 is a graph of the effectiveness of an anti-aging test according to an embodiment of the present invention;
FIG. 4 is a graph illustrating the effect of skin elasticity tests according to embodiments of the present invention;
FIG. 5 is a graph showing the effect of an anti-glycation assay performed according to an embodiment of the present invention.
Detailed Description
The moisturizing cream with the anti-aging effect strengthened is prepared from the following raw materials in percentage by weight:
the phases in the table above are used to group the components at the time of preparation, wherein: the phase A comprises: PEG-8C 12-20 acid ester, caprylic/capric triglyceride, hydrogenated polyisobutene, tri (octyldodecanol) citrate, polydimethylsiloxane, phenyl trimethicone, sunflower seed oil, soybean oil, peony root extract, tocopheryl acetate, potassium cetyl phosphate, cetearyl alcohol; the phase B comprises: deionized water, isoprene glycol, glycerol, inulin lauryl carbamate, acryloyl dimethyl ammonium taurate/VP copolymer, xanthan gum, p-hydroxyacetophenone and EDTA disodium; the phase C comprises: lycium ruthenicum raw stock, yeast/barley seed fermentation product filtrate, cucumber fruit water, cell activation factor OXY229PF, ginseng root extract, perilla seed extract, wenzhou mandarin orange peel extract, generepair beauty extract GENEWHITE-D60, magnetite pentaviti N, soapberry fruit extract, tara gum, glycerin, propylene glycol, pomegranate fruit extract, caffeine, silicone triol alginate, butylene glycol, carrageen crispa extract, austenitic seaweed extract, bilberry juice, bilberry extract, acetyl chitosamine, yeast extract, sodium hyaluronate, ergothioneine, matsutake mushroom extract, 1, 2-pentanediol, ethylhexylglycerin, tetrahexyldecanol ascorbate, Uncaria tomentosa extract, gelidium amabilis extract, purslane extract, yeast fermentation product extract, lecithin, oleic acid, xanthan gum, sorbitol (sugar) alcohol, glycerin, sodium stearate, sorbitol (sodium stearate), sorbitol) (sodium stearate), sorbitol (sorbitol) (sodium stearate), sorbitol) (sorbitol, Sodium citrate, and SHUANGZIYOU.
The invention also provides a preparation method of the moisturizing cream with the anti-aging effect, which mainly comprises the following steps:
accurately weighing various raw materials for later use;
cleaning an emulsifying pot, mixing the phase A, adding the mixture into an oil phase pot, and heating to 85 ℃;
thirdly, adding the phase B into a water phase pot, heating to 85 ℃, stirring uniformly, and keeping the temperature for half an hour;
pumping the phase A into an emulsifying pot, pumping the phase B into the emulsifying pot, homogenizing, stirring and emulsifying;
cooling to 45 ℃, sequentially adding the C phase components, and uniformly stirring;
sixthly, sampling, measuring pH, discharging after the semi-finished product sampling detection meets the standard;
and seventhly, after the semi-finished product is inspected to be qualified, filling and packaging, and after the finished product is inspected to be qualified, warehousing.
The invention will be described in further detail with reference to the following figures and specific examples.
Example 1
Example 2
Example 3
The difference of the three implementation cases is that the addition proportions of lycium ruthenicum raw stock with serial number 9, the cell activating factor OXY229PF with serial number 13, the gene repairing Meiji No. 15, the Meiji No. GENEWHITE-D60 and the Pentaavitin magnet with serial number 16 are different.
Comparative example (a cream of some international known brand on the market):
the skin care products of the three examples were tested and checked for efficacy and compared to the comparative examples.
1) Moisture retention test
60 female volunteers aged 28-50 years are found, 20 testers are selected from each sample, the skin care product with the anti-aging effect of the embodiment and the comparative case product are respectively used on the face, the water content (%) of the skin cuticle after the samples are used is respectively measured by an instrument MOISTURE METERSCMSC1212(DELFIN) for 0h, 0.5h, 1h, 2h, 4h and 8h, and the result is shown in figure 1.
The experimental results show that the moisture retention performance of the product is obviously improved compared with that of a comparative case product.
2) Skin smoothness change rate test
| Sample(s) | Before use | After use |
| Example 1 | 3.1755 | 1.7102 |
| Example 2 | 3.205 | 1.9087 |
| Example 3 | 3.1205 | 2.025 |
| Comparative example | 3.1521 | 2.2875 |
The experimental results show that the skin smoothness of the invention is better than that of the comparative case, and the anti-aging effect is more obvious.
3) Anti-aging test
The skin care products of the examples and the nutrient solutions of the comparative examples were used to cultivate caenorhabditis elegans, and then the effects of the skin care products of the examples and the comparative examples on the longevity of model organisms caenorhabditis elegans were examined. The test results are shown in the following table and fig. 3.
| Sample(s) | Average life (sky) | Maximum life (sky) |
| Example 1 | 12.95±0.35d | 20.12±1.35d |
| Example 2 | 11.52±0.21d | 18.26±1.22d |
| Example 3 | 10.75±0.25d | 16.26±1.25d |
| Comparative example | 8.87±0.35d | 11.33±1.16d |
From the above experimental results, the anti-aging capability of the invention is better than that of the comparative case product.
4) Skin elasticity test
| Sample (I) | Before use | After 2 weeks of use | After 4 weeks of use |
| Example 1 | 0.265 | 0.352 | 0.496 |
| Example 2 | 0.273 | 0.335 | 0.425 |
| Example 3 | 0.251 | 0.296 | 0.371 |
| Comparative example | 0.266 | 0.278 | 0.358 |
From the above experimental results, the skin elasticity recovery effect of the invention is better than that of the comparative case product.
5) Anti-glycation assay
15 female volunteers between 18-50 years of age were identified and the anti-aging skin care products and comparative products of the above examples were applied to the face, respectively, twice a day for 30 consecutive days without any other product during the test period. The glycation inhibition results obtained from the measurements using the german MAP580 skin tester are shown in the following table and fig. 5.
| Sample (I) | Example 1 | Example 2 | Example 3 | Comparative example |
| Glycation inhibition (%) | 42 | 38 | 31 | 22 |
From the above experimental results, the anti-glycation ability of the invention is more remarkable than the anti-glycation effect of the comparative case product.
The above description is only a preferred embodiment of the present invention, and the present invention is not limited to the above embodiment, and there may be some slight structural changes in the implementation, and if there are various changes or modifications to the present invention without departing from the spirit and scope of the present invention, and within the claims and equivalent technical scope of the present invention, the present invention also includes those changes and modifications.
Claims (7)
1. The moisturizing cream with the anti-aging effect is characterized by comprising the following components in percentage by weight: 1-100% of water; 1-10% of C12-20 acid PEG-8 ester; 0.1-4% of isoprene glycol; 0.1-4% of caprylic/capric triglyceride; 1-10% of hydrogenated polyisobutene; 1-5% of tri (octyldodecanol) citrate; 1-5% of polydimethylsiloxane; 1-5% of phenyl trimethyl siloxane; 0.1-5% of sunflower seed oil; 0.1-5% of cucumber juice; 0.1-5% of ginseng root extract; 0.1-5% of citrus unshiu peel extract; 0.1-5% of perilla seed extract; 0.1-5% of soapberry fruit extract; 0.1-5% of Caesalpinia spinosa gum; 0.1-5% of pomegranate fruit extract; 0.1-5% of caffeine; 0.1-5% of Chondrus crispus extract; 0.1-5% of an austenitic seaweed extract; 0.1-5% of vaccinium myrtillus juice; 0.1-5% of vaccinium myrtillus fruit extract; 0.1-5% of acetyl chitosamine; 0.1-5% of yeast extract; 0.1-5% of wild soybean oil; 0.1-5% of peony root extract; 0.1-1% of sodium hyaluronate; 0.1-5% of ergothioneine; 0.1-5% of Armillaria matsutake extract; 0.1-5% of 1, 2-pentanediol; 0.1-5% of ethylhexyl glycerin; 0.1-5% of tetrahexyldecyl ascorbate; 0.1-5% of a Uncaria tomentosa extract; 0.1-5% of a broccoli extract; 0.1-5% of purslane extract; 0.1-5% of yeast fermentation product extract; 0.1-5% of tocopherol acetate; 0.1-5% of potassium cetyl phosphate; cetearyl alcohol 0.1-5%; inulin lauryl carbamate 0.1-5%; 0.1-5% of lecithin; 0.1-5% of siloxane triol alginate; 0.1-5% of oleic acid; 0.1-5% of sorbitol (sugar); 0.1-5% of glycerol; 0.1-5% of butanediol; 0.1-5% of propylene glycol; 0.1-5% of acryloyl dimethyl ammonium taurate/VP copolymer; 0.1-5% of xanthan gum; 0.01-1% of p-hydroxyacetophenone; 0.01-1% of EDTA disodium; 0.1-1% of sodium citrate; 1-5% of yeast/barley seed fermentation product filtrate; the water-locking magnet PentaavitiN 1-10%; 3-10% of lycium ruthenicum raw stock; OXY229PF0.2-5% of cell activating factors; gene repair Mei Jing GENEWHITE-D600.2-5%; 0.1-5% of double purple oil.
2. The anti-aging effect-intensified moisturizing cream according to claim 1, wherein: the water-locking magnet Pentaavitin comprises saccharide isomerate and deionized water.
3. The anti-aging effect-intensified moisturizing cream according to claim 1, wherein: the lycium ruthenicum raw stock comprises a lycium ruthenicum extract and a lactic acid bacteria fermentation product.
4. The anti-aging effect-intensified moisturizing cream as claimed in claim 1, wherein: the cell activating factor OXY229PF comprises deionized water, glycerol, yeast lysate, valine, threonine, glycine, and glutamic acid.
5. The anti-aging effect-intensified moisturizing cream as claimed in claim 1, wherein: the gene repair beauty extract GENEWHITE-D60 comprises Vitex agnus-castus extract, hedyotis diffusa extract and calendula extract.
6. The anti-aging effect-intensified moisturizing cream according to claim 1, wherein: the double purple oil comprises Sinkiang arnebia root extract, caprylic/capric triglyceride, perilla seed extract and pentaerythritol tetra (di-tert-butyl hydroxy hydrocinnamic acid) ester.
7. A method for preparing the anti-aging effect-potentiated moisturizing cream according to any one of claims 1 to 6, comprising the steps of:
accurately weighing various raw materials for later use;
cleaning an emulsifying pot, mixing the phase A, adding the mixture into an oil phase pot, and heating to 85 ℃;
thirdly, adding the phase B into a water phase pot, heating to 85 ℃, stirring uniformly, and keeping the temperature for half an hour;
pumping the phase A into an emulsifying pot, pumping the phase B into the emulsifying pot, homogenizing, stirring and emulsifying;
cooling to 45 ℃, sequentially adding the C phase components, and uniformly stirring;
sixthly, sampling, measuring pH, discharging after the semi-product sampling detection meets the standard;
seventhly, after the semi-finished product is inspected to be qualified, filling and packaging are carried out, and after the finished product is inspected to be qualified, the finished product is put into a warehouse;
the phase A comprises: PEG-8C 12-20 acid ester, caprylic/capric triglyceride, hydrogenated polyisobutene, tri (octyldodecanol) citrate, polydimethylsiloxane, phenyl trimethicone, sunflower seed oil, soybean oil, peony root extract, tocopheryl acetate, potassium cetyl phosphate, cetearyl alcohol;
the phase B comprises: deionized water, isoprene glycol, glycerol, inulin lauryl carbamate, acryloyl dimethyl ammonium taurate/VP copolymer, xanthan gum, p-hydroxyacetophenone and EDTA disodium;
the phase C comprises: lycium ruthenicum puree, yeast/barley seed fermentation product filtrate, cucumber fruit water, cell activating factor OXY229PF, ginseng root extract, perilla seed extract, wenzhou mandarin orange peel extract, generepair beauty extract GENEWHITE-D60, magnetite pintaaviti, soapberry fruit extract, tara gum, glycerin, propylene glycol, pomegranate fruit extract, caffeine, silicone triol alginate, butylene glycol, rugose carrageenan extract, austenitic seaweed extract, bilberry juice, bilberry fruit extract, acetyl chitosamine, yeast extract, sodium hyaluronate, ergothioneine, pine mushroom extract, 1, 2-pentanediol, ethylhexylglycerin, tetrahexyldecanol ascorbate, Uncaria tomentosa extract, gelidium amabilis extract, purslane extract, yeast fermentation product extract, lecithin, oleic acid, xanthan gum, sorbitol extract, glycerin, sorbitol, and glycerin, Sodium citrate and double purple oil.
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| CN115804736A (en) * | 2022-12-14 | 2023-03-17 | 广州臻颜化妆品有限公司 | Multi-effect lip balm and preparation method thereof |
| CN115813795A (en) * | 2022-12-30 | 2023-03-21 | 泉后(广州)生物科技研究院有限公司 | Anti-wrinkle composition and application thereof |
| CN115919698A (en) * | 2023-01-09 | 2023-04-07 | 广州德芙化妆品有限公司 | Composition with effects of tightening and resisting wrinkles and application thereof |
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| CN113768853A (en) * | 2021-10-12 | 2021-12-10 | 广州市雅创化妆品有限公司 | Whitening and spot-fading composition as well as preparation method and application thereof |
| CN113893215A (en) * | 2021-10-09 | 2022-01-07 | 广州市涵美化妆品有限公司 | Eye tightening and repairing composition, application, eye cream and preparation method thereof |
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| CN113893215A (en) * | 2021-10-09 | 2022-01-07 | 广州市涵美化妆品有限公司 | Eye tightening and repairing composition, application, eye cream and preparation method thereof |
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| CN115804736A (en) * | 2022-12-14 | 2023-03-17 | 广州臻颜化妆品有限公司 | Multi-effect lip balm and preparation method thereof |
| CN115804736B (en) * | 2022-12-14 | 2024-04-26 | 广州臻颜化妆品有限公司 | Multi-effect lip balm and preparation method thereof |
| CN115813795A (en) * | 2022-12-30 | 2023-03-21 | 泉后(广州)生物科技研究院有限公司 | Anti-wrinkle composition and application thereof |
| CN115919698A (en) * | 2023-01-09 | 2023-04-07 | 广州德芙化妆品有限公司 | Composition with effects of tightening and resisting wrinkles and application thereof |
| CN115919698B (en) * | 2023-01-09 | 2024-02-09 | 广州德芙化妆品有限公司 | Composition with tightening and anti-wrinkle effects and application thereof |
| CN117180125A (en) * | 2023-10-23 | 2023-12-08 | 广东康容实业有限公司 | Plant allergy-relieving and red-dispelling composition and preparation method thereof |
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