CN108671163A - Herbal mixture bactericidal composition and its application in washing shield product - Google Patents
Herbal mixture bactericidal composition and its application in washing shield product Download PDFInfo
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- CN108671163A CN108671163A CN201810847993.4A CN201810847993A CN108671163A CN 108671163 A CN108671163 A CN 108671163A CN 201810847993 A CN201810847993 A CN 201810847993A CN 108671163 A CN108671163 A CN 108671163A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
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Abstract
A kind of application the present invention relates to herbal mixture bactericidal composition and its in washing shield product, the herbal mixture bactericidal composition by weight, including following components：1~10 part of Melaleuca alternifolia leaf powder, 0.1~5 part of Melaleuca alternifolia leaf oil, 1~10 part of radix scutellariae extracting solution, 0.05~0.5 part of citronella grass oil.Above-mentioned herbal mixture bactericidal composition, each component is arranged in pairs or groups according to special ratios, the multiple efficacies ingredient being rich in is reconciled mutually, is cooperateed with, and is played and is inhibited pathogenic microorganisms, balance skin surface flora, isolation and remove the harmful substance on skin and reinforce the trophism to Skin Cell.Also, component is natural plant composition selected by the herbal mixture bactericidal composition, environmentally protective, has no toxic side effect, does not stimulate mildly.
Description
Technical field
The present invention relates to washing product technical fields, more particularly to a kind of herbal mixture bactericidal composition and its are washing shield
Application in product.
Background technology
With the promotion of people's consumption consciousness, consumer is in the safety for selecting the when of washing shield cleaning product increasingly to pay attention to product
Property, natural skin care is pursued, containing there are many washing products of medicinal plant extract can meet people for natural, green, strong
The demand of health.However, most of washing product is all to lack real antibacterial effect based on cleaning, or addition is disobeyed in the market
Prohibit ingredient, irritation is strong, and damage skin causes secondary injury.
Invention content
Based on this, it is necessary to provide and a kind of natural be capable of the effectively herbal mixture bactericidal composition of antibacterial and its washing shield
Application in product.
A kind of herbal mixture bactericidal composition, by weight, including following components：
The herbal mixture bactericidal composition in one of the embodiments, by weight, including following components：
The herbal mixture bactericidal composition in one of the embodiments, by weight, including following components：
The radix scutellariae extracting solution is prepared by the following method in one of the embodiments,：
Weighing radix scutellariae root skin adds water to boil, filter out solid to get.
The method of the tanning includes in one of the embodiments,：Radix scutellariae root skin addition 250ml described in per 15g~
350ml water, tanning 30min~60min to extraction raffinate are 80ml~120ml.
The Melaleuca alternifolia leaf powder is prepared by the following method in one of the embodiments,：
Fresh braches of the single diameter of Melaleuca alternifolia no more than 0.5cm and blade thereon are chosen, dry, crush,
Sieving to get.
The mesh screen of 60 mesh~180 is selected in the sieving in one of the embodiments,.
The present invention also provides application of the herbal mixture bactericidal composition of any of the above-described embodiment in preparing washing product.
The present invention also provides a kind of washing products, and it includes wash described in shield matrix, solvent and any of the above-described embodiment
Herbal mixture bactericidal composition.
The present invention also provides a kind of preparation methods of the washing product, include the following steps：
The herbal mixture bactericidal composition is mixed in the solvent, adds described wash in shield matrix.
The solvent is propylene glycol and/or butanediol in one of the embodiments,.
The raw material of the herbal mixture bactericidal composition of the present invention is described below：
Melaleuca alternifolia leaf oil is called Australia tea tree essential oil, is pure natural plant extract, efficient fungicide in being.
Melaleuca alternifolia leaf oil can antibacterial mite-removing, convergence pore, and have very strong transdermal penetration facilitation, component can be helped
In other active ingredients absorption.The main chemical compositions of Melaleuca alternifolia leaf oil include 4- terpinols and 1,8- folium eucalyptis
The antibacterial activity of element, essential oil enhances, the thorn of 1, 8-Cineole and essential oil as 4- pine tar determining alcohols increase under certain condition
It is related to swash property, 1, 8-Cineole concentration is lower, and irritation is smaller.
Melaleuca alternifolia leaf powder contains the ingredients such as volatile oil, terpinol, alkenes, and particulate powder, which is removed to contain, has more than 1%
Leaf oil outside, wash shield during may also function as massage effect, can remove skin surface drying aging cutin layer, remove obstruction
The dirt and sebum of pore adjust sebum metabolism, improve skin environment.
Baical Skullcap root P.E has antibacterial anti-inflammatory, resists containing scutelloside, baicalein, flavone compound, amino acid, carbohydrate etc.
The effects that allergy, anti-oxidant, removing free radical and conditioning skin.Baical Skullcap root P.E can clearing heat and detoxicating, scattered silt be stopped blooding, diuresis disappears
It is swollen；Elastoser can be inhibited to secrete, eliminate free radical and played to increase skin metabolism, skin elasticity and wrinkle resistance
The effect of anti-aging；Brain amide can be promoted to secrete, and improving sebum keeps skin soft and moist；The resistance that can inhibit dermatitis, enhance skin
Power has anti-inflammatory；The histamine that release can be neutralized, has the ability for preventing allergy.
Citronella grass oil contains the ingredients such as citronellal, geraniol and citronellol, can be used for cleaning Oily, plays sterilization and disappears
Inflammation, the effect for relaxing tendons and activating collaterals, relieving pain, making dermalaxia.There is citronella grass oil strong Chinese pepper fragrance, pure and fresh brains to eliminate big
Brainfag, while can reconcile the smell of Melaleuca alternifolia leaf oil, keep component smell harmony more comfortable.
Compared with existing scheme, the invention has the advantages that：
Above-mentioned herbal mixture bactericidal composition, each component are arranged in pairs or groups according to special ratios, the multiple efficacies ingredient being rich in
It reconciles mutually, collaboration, the killing of the pathogenic bacteria such as Escherichia coli, staphylococcus aureus, Candida albicans and Pseudomonas aeruginosa is imitated
Fruit is substantially better than effect when each component is used alone.
Above-mentioned herbal mixture bactericidal composition can play and inhibit pathogenic microorganisms, balance skin surface flora, be isolated and go
The effect of harmful substance and reinforcement Skin Cell nutrition apart from skin.Selected component is natural plant composition, environmentally protective,
It has no toxic side effect, it is mild non-stimulated.
Test result shows that the face cream containing above-mentioned herbal mixture bactericidal composition there is apparent treatment to imitate acne
Fruit contains only the face cream of single medicine ingredient, or low without curative effect or cure rate to acne, and containing above-mentioned multiple
The face cream of square Chinese medicine antibacterial composition can significantly improve acne cure rate in a short time.
Specific implementation mode
To facilitate the understanding of the present invention, below in conjunction with specific embodiment to invention is more fully described.But
The present invention can realize in many different forms, however it is not limited to embodiment described herein.On the contrary, providing these realities
The purpose for applying example is to make the disclosure of the present invention more thorough and comprehensive.
Unless otherwise defined, all of technologies and scientific terms used here by the article and belong to the technical field of the present invention
The normally understood meaning of technical staff is identical.Used term is intended merely to description tool in the description of the invention herein
The purpose of the embodiment of body, it is not intended that in the limitation present invention.
The Melaleuca alternifolia leaf powder that following embodiment and comparative example uses is prepared by method comprising the following steps
It arrives：
Fresh braches of the single diameter of Melaleuca alternifolia no more than 0.5cm and blade thereon are chosen, is cleaned with clear water,
After drying, shearing branch to every section of about 2cm, is crushed with pulverizer, with 60 to 180 mesh screens sieving 3 times to get.
The Melaleuca alternifolia leaf oil that following embodiment and comparative example uses is prepared by method comprising the following steps
It arrives：
Fresh Melaleuca alternifolia branches and leaves are chosen, distillation extraction are heated by water distillation apparatus, condensation makes water-oil separating obtain
To extraction crude oil, harmful substance is filtered out through purification apparatus, remains most active ingredient in Australia tea tree.
The radix scutellariae extracting solution that following embodiment and comparative example uses is prepared by method comprising the following steps：
It weighs radix scutellariae root skin and is added 250ml~350ml water per radix scutellariae root skin described in 15g, tanning 30min~60min is to remaining
Liquid is 80ml~120ml, is filtered with 50 mesh filter screens, and radix scutellariae extracting solution is obtained, and sealing, which is placed in 4 DEG C of refrigerators, to be stored.
The citronella grass oil that following embodiment and comparative example uses is same commercial product.
Embodiment 1
Weigh Melaleuca alternifolia leaf powder 1g, Melaleuca alternifolia leaf oil 5g, radix scutellariae extracting solution 10g and citronella grass oil
0.05g, with propylene glycol solvent dissolve a concentration of 10wt% herbal mixture bactericidal composition mixed liquor.
Shield matrix (water, Sodium Hyaluronate, butanediol, hydrolysis are washed into the addition of above-mentioned herbal mixture bactericidal composition mixed liquor
Collagen and lipid etc.) in, it stirs evenly, face cream is made.
Embodiment 2
Weigh Melaleuca alternifolia leaf powder 10g, Melaleuca alternifolia leaf oil 0.1g, radix scutellariae extracting solution 1g and citronella grass oil
0.5g, with propylene glycol solvent dissolve a concentration of 10wt% herbal mixture bactericidal composition mixed liquor.
Shield matrix (water, Sodium Hyaluronate, butanediol, hydrolysis are washed into the addition of above-mentioned herbal mixture bactericidal composition mixed liquor
Collagen and lipid etc.) in, it stirs evenly, face cream is made.
Embodiment 3
Weigh Melaleuca alternifolia leaf powder 5g, Melaleuca alternifolia leaf oil 3g, radix scutellariae extracting solution 8g and citronella grass oil
0.05g, with propylene glycol solvent dissolve a concentration of 10wt% herbal mixture bactericidal composition mixed liquor.
Shield matrix (water, Sodium Hyaluronate, butanediol, hydrolysis are washed into the addition of above-mentioned herbal mixture bactericidal composition mixed liquor
Collagen and lipid etc.) in, it stirs evenly, face cream is made.
Embodiment 4
Weigh Melaleuca alternifolia leaf powder 8g, Melaleuca alternifolia leaf oil 0.5g, radix scutellariae extracting solution 3g and citronella grass oil
0.3g, with propylene glycol solvent dissolve a concentration of 10wt% herbal mixture bactericidal composition mixed liquor.
Shield matrix (water, Sodium Hyaluronate, butanediol, hydrolysis are washed into the addition of above-mentioned herbal mixture bactericidal composition mixed liquor
Collagen and lipid etc.) in, it stirs evenly, face cream is made.
Embodiment 5
Weigh Melaleuca alternifolia leaf powder 5g, Melaleuca alternifolia leaf oil 2.5g, radix scutellariae extracting solution 5g and citronella grass oil
0.25g, with propylene glycol solvent dissolve a concentration of 10wt% herbal mixture bactericidal composition mixed liquor.
Shield matrix (water, Sodium Hyaluronate, butanediol, hydrolysis are washed into the addition of above-mentioned herbal mixture bactericidal composition mixed liquor
Collagen and lipid etc.) in, it stirs evenly, face cream is made.
Comparative example 1
Weigh Melaleuca alternifolia leaf powder with propylene glycol solvent dissolve a concentration of 10wt% herbal mixture antibacterial combination
Object mixed liquor.
Shield matrix (water, Sodium Hyaluronate, butanediol, hydrolysis are washed into the addition of above-mentioned herbal mixture bactericidal composition mixed liquor
Collagen and lipid etc.) in, it stirs evenly, face cream is made.
Comparative example 2
Weigh Melaleuca alternifolia leaf oil with propylene glycol solvent dissolve a concentration of 10wt% herbal mixture antibacterial combination
Object mixed liquor.
Shield matrix (water, Sodium Hyaluronate, butanediol, hydrolysis are washed into the addition of above-mentioned herbal mixture bactericidal composition mixed liquor
Collagen and lipid etc.) in, it stirs evenly, face cream is made.
Comparative example 3
Weigh radix scutellariae extracting solution with propylene glycol solvent dissolve a concentration of 10wt% herbal mixture bactericidal composition mix
Liquid.
Shield matrix (water, Sodium Hyaluronate, butanediol, hydrolysis are washed into the addition of above-mentioned herbal mixture bactericidal composition mixed liquor
Collagen and lipid etc.) in, it stirs evenly, face cream is made.
Comparative example 4
Weigh citronella grass oil with propylene glycol solvent dissolve a concentration of 10wt% herbal mixture bactericidal composition mixed liquor.
Shield matrix (water, Sodium Hyaluronate, butanediol, hydrolysis are washed into the addition of above-mentioned herbal mixture bactericidal composition mixed liquor
Collagen and lipid etc.) in, it stirs evenly, face cream is made.
Suspension quantitative bactericidal test
Culture 18~Escherichia coli for 24 hours, staphylococcus aureus, Pseudomonas aeruginosa, Candida albicans bacterium colony are taken, using straight
Bacterium colony suspension preparation method is connect, the bacteria suspension for meeting requirement of experiment is prepared into.
It is added in sterile test tube in compound prepared by 1ml experiment bacteria suspensions and 4ml Examples 1 to 5 and comparative example 1~4
Medicine bactericidal composition mixed liquor, mixing, constant temperature to (20 ± 1 DEG C) act on 5min and 10min.0.5ml sample liquids are taken to be added to
Mixing in 4.5ml neutralizers (+1% glycine+0.03mol/L PBS of+0.5% lecithin of 2% Tween-80) test tube neutralizes and makees
Use 10min.1.0ml sample liquids are drawn respectively, are measured survival bacterium number by viable bacteria culture method of counting, are calculated killing rate.On tablet
When the clump count of growth is more, after 10 times of dilutions of series can be carried out, then carries out viable bacteria culture and count.It is replaced simultaneously with dilution real
Herbal mixture bactericidal composition mixed liquor prepared by example 1~5 and comparative example 1~4 is applied, parallel test is carried out, as positive control.
As a result as follows：
Embodiment 1
Embodiment 2
Embodiment 3
Embodiment 4
Embodiment 5
Comparative example 1
Comparative example 2
Comparative example 3
Comparative example 4
The data from table are as it can be seen that compared with each component is used alone, herbal mixture antibacterial group that Examples 1 to 5 is provided
It is mutual by the Melaleuca alternifolia leaf powder of specific proportioning, Melaleuca alternifolia leaf oil, radix scutellariae extracting solution and citronella grass oil to close object
Collaboration has more obvious killing to pathogenic bacteria such as Escherichia coli, staphylococcus aureus, Candida albicans and Pseudomonas aeruginosas
The herbal mixture bactericidal composition that effect, wherein embodiment 5 are provided acts on 10min, sterilization Shuai≤99.9%.
To the measurement of staphylococcus aureus minimum inhibitory concentration (MIC value)
Test method：Minimum inhibitory concentration (MIC), which measures, uses micro-dilution method, is compared and is diluted with EP pipes, by embodiment 1
~5 and the herbal mixture bactericidal composition mixed liquor for preparing of comparative example 1~4 dilute 8 concentration, each pipe concentration is followed successively by 50%,
25%, 12.5%, 6.25%, 3.13%, 1.56%, 0.78%, 0.39%, 0.20%, 0.10%, it is added in 96 orifice plates, often
50 μ l of hole.The staphylococcus aureus bacterium solution (10 that will have been diluted6Cfu/ml it) is added and has Examples 1 to 5 and comparative example 1~4
In the hole of the herbal mixture bactericidal composition mixed liquor of preparation, per hole 50ul, covers, set in 35 DEG C and cultivate for 24 hours.Visually to see
It examines, drug minimum concentration pipe is without bacterial growth person, the MIC value of as tested bacterium.As a result as follows：
The data from table are as it can be seen that compared with each component is used alone, herbal mixture antibacterial group that Examples 1 to 5 is provided
It is mutual by the Melaleuca alternifolia leaf powder of specific proportioning, Melaleuca alternifolia leaf oil, radix scutellariae extracting solution and citronella grass oil to close object
Collaboration, is substantially reduced staphylococcus aureus minimum inhibitory concentration.
The treatment test of teenager's face acnes
Test object：14 years old~20 years old teenager with face acnes.Each test group is 25.
Test method：Test carries out 14 days, daily morning and evening each Example 1~5 and 1~4 blank of comparative example shield obtained
3~5g of skin frost is applied to the facial positions of acne.
Testing standard：1. fully recovering：Acne disappears；2. effective：Acne mitigates to a little；3. effectively：Acne mitigates；4. nothing
Effect：Acne is not played a role.
Treatment test effect see the table below.
| Sample | Recovery from illness | It is effective | Effectively | In vain | Cure rate | Total effective rate |
| Embodiment 1 | 8 | 7 | 3 | 7 | 32% | 72% |
| Embodiment 2 | 11 | 4 | 4 | 6 | 44% | 76% |
| Embodiment 3 | 15 | 2 | 5 | 3 | 60% | 88% |
| Embodiment 4 | 13 | 6 | 3 | 3 | 52% | 88% |
| Embodiment 5 | 15 | 6 | 3 | 1 | 60% | 96% |
| Comparative example 1 | 1 | 5 | 6 | 13 | 8% | 48% |
| Comparative example 2 | 3 | 5 | 6 | 11 | 12% | 56% |
| Comparative example 3 | 0 | 2 | 7 | 16 | 0 | 36% |
| Comparative example 4 | 0 | 0 | 10 | 15 | 0 | 40% |
The data from table are as it can be seen that compared with comparative example 1~4, the face cream that Examples 1 to 5 is provided eliminates the work(of acne
Effect is relatively apparent, and the effect for the face cream that wherein embodiment 5 is provided is best, illustrates the compound of currently preferred constituent content
Chinese medicine antibacterial composition effect is more preferably.During product test of the present invention, do not find that allergy occur in toxic side effect, no an example
Reaction, only 3 local skins have the person of festering, and are having slight tingling sensation, third to disappear behind day using first two days.
Above-mentioned herbal mixture bactericidal composition, each component are arranged in pairs or groups according to special ratios, the multiple efficacies ingredient being rich in
It reconciles mutually, collaboration, plays the harmful substance inhibited on pathogenic microorganisms, balance skin surface flora, isolation and removal skin
With reinforcement to the trophism of Skin Cell.
Above-mentioned herbal mixture bactericidal composition, selected component is natural plant composition, environmentally protective, is had no toxic side effect,
It does not stimulate mildly.
Each technical characteristic of embodiment described above can be combined arbitrarily, to keep description succinct, not to above-mentioned reality
It applies all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited
In contradiction, it is all considered to be the range of this specification record.
Several embodiments of the invention above described embodiment only expresses, the description thereof is more specific and detailed, but simultaneously
It cannot therefore be construed as limiting the scope of the patent.It should be pointed out that coming for those of ordinary skill in the art
It says, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to the protection of the present invention
Range.Therefore, the protection domain of patent of the present invention should be determined by the appended claims.
Claims (10)
1. a kind of herbal mixture bactericidal composition, which is characterized in that by weight, including following components：
2. herbal mixture bactericidal composition as described in claim 1, which is characterized in that by weight, including following components：
3. herbal mixture bactericidal composition as claimed in claim 2, which is characterized in that by weight, including following components：
4. such as claims 1 to 3 any one of them herbal mixture bactericidal composition, which is characterized in that the radix scutellariae extracting solution
It is prepared by the following method：
Weighing radix scutellariae root skin adds water to boil, filter out solid to get.
5. herbal mixture bactericidal composition as claimed in claim 4, which is characterized in that the method for the tanning includes：Per 15g
250ml~350ml water is added in the radix scutellariae root skin, and tanning 30min~60min to extraction raffinate is 80ml~120ml.
6. such as claims 1 to 3 any one of them herbal mixture bactericidal composition, which is characterized in that the alternate leaf white thousand
Layer leaf powder is prepared by the following method：
Fresh braches of the single diameter of Melaleuca alternifolia no more than 0.5cm and blade thereon are chosen, dries, crush, be sieved,
To obtain the final product.
7. herbal mixture bactericidal composition as claimed in claim 6, which is characterized in that the mesh of 60 mesh~180 is selected in the sieving
Sieve.
8. such as application of the claim 1~7 any one of them herbal mixture bactericidal composition in preparing washing product.
9. a kind of washing product, which is characterized in that protect matrix, solvent and such as claim 1~7 any one of them comprising washing
Herbal mixture bactericidal composition.
10. a kind of preparation method of washing product as claimed in claim 9, which is characterized in that include the following steps：
The herbal mixture bactericidal composition is mixed in the solvent, adds described wash in shield matrix.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810847993.4A CN108671163B (en) | 2018-07-27 | 2018-07-27 | Compound traditional Chinese medicine antibacterial composition and application thereof in washing and protecting products |
| PCT/CN2019/093400 WO2020019929A1 (en) | 2018-07-27 | 2019-06-27 | Compound chinese traditional medicine antibacterial composition and application thereof in toiletry products |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810847993.4A CN108671163B (en) | 2018-07-27 | 2018-07-27 | Compound traditional Chinese medicine antibacterial composition and application thereof in washing and protecting products |
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| CN108671163B CN108671163B (en) | 2021-01-05 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020019929A1 (en) * | 2018-07-27 | 2020-01-30 | 广东成烨泰生物科技有限公司 | Compound chinese traditional medicine antibacterial composition and application thereof in toiletry products |
| CN111701003A (en) * | 2020-05-22 | 2020-09-25 | 黄欣 | Application of Huoxiang Zhengqi compound in preparation of external washing and protecting product |
| CN111991297A (en) * | 2020-09-15 | 2020-11-27 | 广州莱约生物科技有限公司 | Anti-aging wrinkle-removing composition and preparation method and application thereof |
| CN112675093A (en) * | 2021-01-11 | 2021-04-20 | 广东成烨泰生物科技有限公司 | Plant scalp care composition, scalp care solution and preparation method thereof |
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| Publication number | Publication date |
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| WO2020019929A1 (en) | 2020-01-30 |
| CN108671163B (en) | 2021-01-05 |
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Application publication date: 20181019 Assignee: Nova Petroleum Guangzhou Co.,Ltd. Assignor: GUANGDONG SEMYTAI BIOTECHNOLOGY Co.,Ltd. Contract record no.: X2023980032257 Denomination of invention: Antibacterial composition of compound Chinese medicine and its application in washing and nursing products Granted publication date: 20210105 License type: Common License Record date: 20230220 |