CN108593380B - 一种组织芯片量产制作方法 - Google Patents
一种组织芯片量产制作方法 Download PDFInfo
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- CN108593380B CN108593380B CN201810381966.2A CN201810381966A CN108593380B CN 108593380 B CN108593380 B CN 108593380B CN 201810381966 A CN201810381966 A CN 201810381966A CN 108593380 B CN108593380 B CN 108593380B
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- 238000004519 manufacturing process Methods 0.000 title claims abstract description 22
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- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 claims abstract description 18
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
- G01N1/06—Devices for withdrawing samples in the solid state, e.g. by cutting providing a thin slice, e.g. microtome
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/36—Embedding or analogous mounting of samples
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/42—Low-temperature sample treatment, e.g. cryofixation
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
- G01N2001/2866—Grinding or homogeneising
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
- G01N2001/2873—Cutting or cleaving
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/36—Embedding or analogous mounting of samples
- G01N2001/364—Embedding or analogous mounting of samples using resins, epoxy
Abstract
Description
Claims (6)
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810381966.2A CN108593380B (zh) | 2018-04-25 | 2018-04-25 | 一种组织芯片量产制作方法 |
KR1020207031934A KR102458364B1 (ko) | 2018-04-25 | 2019-04-20 | 조직 칩 양산 제작 방법 |
PCT/CN2019/083579 WO2019206054A1 (zh) | 2018-04-25 | 2019-04-20 | 一种组织芯片量产制作方法 |
JP2020560136A JP7111833B2 (ja) | 2018-04-25 | 2019-04-20 | 組織チップの量産製造方法 |
MYPI2020005582A MY196704A (en) | 2018-04-25 | 2019-04-20 | Mass Production Manufacturing Method For Tissue Chip |
US17/078,372 US20210041333A1 (en) | 2018-04-25 | 2020-10-23 | Mass production manufacturing method for tissue chip |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810381966.2A CN108593380B (zh) | 2018-04-25 | 2018-04-25 | 一种组织芯片量产制作方法 |
Publications (2)
Publication Number | Publication Date |
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CN108593380A CN108593380A (zh) | 2018-09-28 |
CN108593380B true CN108593380B (zh) | 2021-05-18 |
Family
ID=63609982
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201810381966.2A Active CN108593380B (zh) | 2018-04-25 | 2018-04-25 | 一种组织芯片量产制作方法 |
Country Status (6)
Country | Link |
---|---|
US (1) | US20210041333A1 (zh) |
JP (1) | JP7111833B2 (zh) |
KR (1) | KR102458364B1 (zh) |
CN (1) | CN108593380B (zh) |
MY (1) | MY196704A (zh) |
WO (1) | WO2019206054A1 (zh) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI820061B (zh) * | 2017-12-06 | 2023-11-01 | 美商建南德克公司 | 用於免疫組織化學的合成對照 |
CN108593380B (zh) * | 2018-04-25 | 2021-05-18 | 复旦大学附属中山医院 | 一种组织芯片量产制作方法 |
CN111088216A (zh) * | 2019-12-16 | 2020-05-01 | 齐妍 | 一种用于石蜡包埋组织分离检测细胞的方法 |
CN113759143B (zh) * | 2021-09-01 | 2024-04-26 | 广州耐确医疗器械有限责任公司 | 一种新型全自动组织芯片仪 |
CN114002030A (zh) * | 2021-10-15 | 2022-02-01 | 北京龙迈达斯科技开发有限公司 | 一种复合型组织芯片及其制备方法 |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6458598B1 (en) | 2001-08-13 | 2002-10-01 | Dako A/S | Process for preparing and presenting a tissue sample for histological study |
AU2002352787A1 (en) | 2001-11-20 | 2003-06-10 | Genentech, Inc. | Cell and tissue arrays and microarrays and methods of use |
CN100451649C (zh) * | 2004-01-08 | 2009-01-14 | 中南大学湘雅医学院肿瘤研究所 | 一种细胞芯片制作方法及其器具 |
WO2008153879A1 (en) * | 2007-06-08 | 2008-12-18 | Regan Spencer Fulton | Method and apparatus for producing high-yield tissue microarray blocks |
JP2009002768A (ja) * | 2007-06-21 | 2009-01-08 | Japan Health Science Foundation | 組織マイクロアレイ作製方法 |
CN201186924Y (zh) * | 2008-03-13 | 2009-01-28 | 陕西省人民医院 | 一种制备细胞芯片的装置 |
CN101556224B (zh) * | 2009-05-18 | 2011-02-16 | 复旦大学附属中山医院 | 一种石蜡组织芯片制作方法 |
CN101694429B (zh) | 2009-10-15 | 2011-03-30 | 复旦大学附属中山医院 | 一种石蜡组织芯片包埋方法 |
JP5674004B2 (ja) | 2010-08-23 | 2015-02-18 | 国立大学法人九州大学 | 組織標本の凍結方法及び保存方法 |
CN102435725A (zh) * | 2011-08-31 | 2012-05-02 | 复旦大学附属中山医院 | 一种简易石蜡组织芯片接种方法 |
CN202471473U (zh) * | 2011-09-14 | 2012-10-03 | 饶莹 | 一种一次成型的组织芯片制作装置 |
KR101434048B1 (ko) * | 2012-12-05 | 2014-08-25 | 삼성전기주식회사 | 세포 박편 표본의 제조 방법 |
CN103869057B (zh) * | 2012-12-13 | 2017-01-18 | 泰州医药城博奥邦科生物科技有限公司 | 穿刺活检组织芯片 |
CN103900864A (zh) * | 2012-12-25 | 2014-07-02 | 泰州医药城博奥邦科生物科技有限公司 | 脱落细胞芯片 |
CN103091151B (zh) * | 2013-01-04 | 2014-10-29 | 复旦大学附属中山医院 | 一种石蜡细胞芯片接种方法 |
CN103439163B (zh) * | 2013-09-04 | 2015-07-15 | 中南大学湘雅三医院 | 活版式组织芯片制备方法及制备仪器 |
CN104034570B (zh) * | 2014-04-29 | 2016-09-14 | 大连工业大学 | 一种海蜇石蜡切片制备方法 |
RU2743169C2 (ru) | 2015-11-06 | 2021-02-15 | Вентана Медикал Системз, Инк. | Репрезентативная диагностика |
CN105259001B (zh) * | 2015-11-13 | 2018-11-20 | 广州市金圻睿生物科技有限责任公司 | 一种用于组织活检的石蜡切片前处理方法 |
CN108593380B (zh) | 2018-04-25 | 2021-05-18 | 复旦大学附属中山医院 | 一种组织芯片量产制作方法 |
-
2018
- 2018-04-25 CN CN201810381966.2A patent/CN108593380B/zh active Active
-
2019
- 2019-04-20 JP JP2020560136A patent/JP7111833B2/ja active Active
- 2019-04-20 KR KR1020207031934A patent/KR102458364B1/ko active IP Right Grant
- 2019-04-20 WO PCT/CN2019/083579 patent/WO2019206054A1/zh active Application Filing
- 2019-04-20 MY MYPI2020005582A patent/MY196704A/en unknown
-
2020
- 2020-10-23 US US17/078,372 patent/US20210041333A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
KR20200142026A (ko) | 2020-12-21 |
KR102458364B1 (ko) | 2022-10-24 |
JP2021518919A (ja) | 2021-08-05 |
WO2019206054A1 (zh) | 2019-10-31 |
CN108593380A (zh) | 2018-09-28 |
JP7111833B2 (ja) | 2022-08-02 |
US20210041333A1 (en) | 2021-02-11 |
MY196704A (en) | 2023-04-30 |
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Application publication date: 20180928 Assignee: FUZHOU MAIXIN BIOTECH, Co.,Ltd. Assignor: ZHONGSHAN HOSPITAL, FUDAN University Contract record no.: X2021980013874 Denomination of invention: A mass production method of tissue chip Granted publication date: 20210518 License type: Common License Record date: 20211202 |
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Application publication date: 20180928 Assignee: Shanghai Xiawei medical laboratory Co.,Ltd. Assignor: ZHONGSHAN HOSPITAL, FUDAN University Contract record no.: X2022980000485 Denomination of invention: A mass production method of tissue chip Granted publication date: 20210518 License type: Common License Record date: 20220113 |
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Application publication date: 20180928 Assignee: Shanghai Dunhui Medical Technology Development Co.,Ltd. Assignor: ZHONGSHAN HOSPITAL, FUDAN University Contract record no.: X2022980000985 Denomination of invention: A mass production method of tissue chip Granted publication date: 20210518 License type: Common License Record date: 20220125 |
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Application publication date: 20180928 Assignee: Shanghai Puen Haihui Medical Laboratory Co.,Ltd. Assignor: ZHONGSHAN HOSPITAL, FUDAN University Contract record no.: X2022980002034 Denomination of invention: A mass production method of tissue chip Granted publication date: 20210518 License type: Common License Record date: 20220301 |
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Application publication date: 20180928 Assignee: Ningbo Baiqiang Medical Instrument Co.,Ltd. Assignor: ZHONGSHAN HOSPITAL, FUDAN University Contract record no.: X2022980012296 Denomination of invention: A method for mass production of tissue chips Granted publication date: 20210518 License type: Common License Record date: 20220810 |