CN108402127A - A kind of health-caring biscuit of auxiliary treatment gout - Google Patents
A kind of health-caring biscuit of auxiliary treatment gout Download PDFInfo
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- A—HUMAN NECESSITIES
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- A21D—TREATMENT, e.g. PRESERVATION, OF FLOUR OR DOUGH, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS; PRESERVATION THEREOF
- A21D13/00—Finished or partly finished bakery products
- A21D13/06—Products with modified nutritive value, e.g. with modified starch content
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- A21—BAKING; EDIBLE DOUGHS
- A21D—TREATMENT, e.g. PRESERVATION, OF FLOUR OR DOUGH, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS; PRESERVATION THEREOF
- A21D2/00—Treatment of flour or dough by adding materials thereto before or during baking
- A21D2/08—Treatment of flour or dough by adding materials thereto before or during baking by adding organic substances
- A21D2/36—Vegetable material
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- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K36/52—Juglandaceae (Walnut family)
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- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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Abstract
A kind of health-caring biscuit of auxiliary treatment gout, raw material and formula composition are：Wheat flour, milk powder, fresh milk, sugar, butter, yeast powder, honey, celery seed powder, brown sugar, pure jujube original powder, walnut oil, Purple Perilla Seed Oil, wormwood, dried orange peel, pueraria lobata, perilla leaf.Celery seed, pueraria lobata, dried orange peel, perilla leaf have the function of that anti-trioxypurine can auxiliary treatment pain wind action in the present invention；Purple Perilla Seed Oil, walnut oil play the role of that intelligence development is cooperateed with part can also to be replaced to make grease needed for biscuit；Celery seed, wormwood, brown sugar powder, pure jujube powder have the effect of blood-enrich；And add fresh milk, honey make biscuit have unique flavor, patient with gout, which takes the biscuit for a long time, can effectively mitigate symptom, can keep fit and healthy, and be free from side effects to human body, and have anti-oxidation efficacy, be free of additive and preservative.
Description
Technical field
The invention belongs to field of health care food, and in particular to a kind of auxiliary treatment gout, it is lowering blood pressure and blood fat, anti-oxidant
Health-caring biscuit.
Background technology
Gout is purine substance metabolic disorder, and serum Uric Acid Concentration, which persistently increases, leads to urate crystal deposition soft tissue institute
The one group of metabolic disease caused.Gout Producing reason is that xanthine oxidase (xanthine oxidase) is generated in human body
Key enzyme during uric acid causes " uricolytic enzyme " to lack since this enzyme increases or activity enhancing, cannot be by uric acid point
Solution is discharged at allantoin soluble easily in water, and urate crystal is made to gather within the organization, forms urarthritis.Clinical signs
For hyperuricemia, gouty acute arthritis, tophaceous deposition, characteristic chornic arthritis and arthritis deformans, often involve
Kidney causes arteriosclerotic kidney and kidney calculus urate.
The common medicine of western medical treatment gout has allopurinol, has the adverse reactions such as liver, bone marrow toxicity；Non- purines choosing
Selecting property xanthine oxidase inhibitor Febuxostat, related researches show that patients higher cardiovascular event incidence.Although
Clinic has some and prevents antipodagric Western medicine, and the symptom of gout is made to be controlled, but more clinical datas show due to existing
The limitation of drug, adverse reaction and the disease medicine less varieties cause medicament selection limited, gout are made not obtain very well
Prevention and treatment.And the continuous improvement of the self health consciousness with people, correlated crowd with auxiliary treatment gout to imitating
The functional food of fruit produces certain consumption demand.The existing health-care effect of functional food, and the not side effect of drug,
It is welcome by people.Existing health care taste is single, alimentary health-care function has its limitation, in order to improve mouthfeel and convenient for depositing
Storage is eaten for a long time wherein usually containing a large amount of additive and preservative, very big burden is brought to health.
Celery seed is taken from the flower of celery, and Uygur medicine thinks that celery seed has air-dispersing, detumescence, diuresis, opens resistance
Stagnant, blood pressure lowering and other effects is taken for a long time and is far superior to other Pharmaceuticals, without any side effects, is best natural green
Food.
Invention content
It is in good taste the present invention provides a kind of manufacture craft is simple, there is anti-oxidation efficacy, be free of additive and preservative
Auxiliary treatment gout health-caring biscuit.
In order to achieve the above object, the technical solution adopted by the present invention is as follows：
A kind of health-caring biscuit of auxiliary treatment gout, making include the following steps：
The raw material of the health-caring biscuit includes：Wheat flour 600g-800g, milk powder 160g-180g, fresh milk 400g-500g, sugar
10g-20g, butter 10g-12g, yeast powder 6g-10g, honey 10g-12g, celery seed powder 2g-4g, brown sugar 10g-12g, pure jujube
Original powder 10g-12g, walnut oil 6g-8g, Purple Perilla Seed Oil 10g-12g, wormwood 6g-8g, dried orange peel 6g-8g, pueraria lobata 6g-8g, perilla leaf
6g-8g；
Its making includes the following steps：
(1) by dried orange peel, methanol 100mL-150mL is added to be heated to reflux 20 minutes, the filtrate of filtering concentrates filtrate under vacuum
Thick medicinal extract is obtained, dry extract is spray-dried to obtain, then be crushed to -100 mesh of 60 mesh, obtains dried orange peel medicinal extract powder；
(2) pueraria lobata and wormwood are added water to cook secondary 2 hours every time, collecting decoction filters to get filtrate, and concentrates under vacuum
Filtrate obtains thick medicinal extract, is spray-dried to obtain dry extract, then is crushed to -100 mesh of 60 mesh, obtains Chinese medical concrete powder；
(3) perilla leaf is taken, adds methanol 150mL-200mL to be ultrasonically treated 30 minutes and filters, the filtrate of filtering is dense under vacuum
Contracting filtrate obtains thick medicinal extract, is spray-dried to obtain dry extract, then is crushed to -100 mesh of 60 mesh, obtains perilla leaf medicinal extract powder；
(4) wheat flour, milk powder, fresh milk, yeast powder and water stir evenly in dough mixing machine, and at dough and ferment, 30 DEG C-
32 DEG C, fermentation time -10 hours 6 hours adds dried orange peel medicinal extract powder, step prepared by sugar, butter, honey, step (2)
(3) perilla leaf medicinal extract powder, brown sugar, the pure jujube original powders of 8g-10g, the purple perilla of the Chinese medical concrete powder, step (4) preparation that prepare
Seed oil, walnut oil and water stir, and dough is made, and stand 20min-30min；
(5) zhang dough is rolled to flour cake with making dough, goes out shape with various Biscuit mold coining, 200 DEG C of -250 DEG C of ovens are baked to
It is ripe, biscuit is obtained, and celery seed powder, remaining pure jujube original powder 2g-4g are sprinkling upon the biscuit surface baked.
Beneficial effects of the present invention：
1. celery seed powder has good xanthine oxidase inhibitor activity；The alkalinity of dried orange peel can also reduce blood uric acid, have
It helps and releases gout symptom；Pueraria lobata has antiinflammation, and pueraria lobata is as expelling wind drug, and above and below the whole body that can pass through, acrid flavour, fragrance can wake up
Spleen, solve it is all poison and control all numbness, that is, effect a permanent cure can anti-trioxypurine, taking stopgap measures can curing arthritis；Pueraria lobata has expelling wind and eliminating dampness, invigorate blood circulation, virtue
Perfume (or spice) is amusing and the effect detoxified, itself has no toxic side effect, kudzuvine root for treating can reduce purine synthesis, make uric acid generate reduce, make it is fast
Purine decomposition rate is accelerated, promotes purine excretion.
2. using Purple Perilla Seed Oil, walnut oil, Purple Perilla Seed Oil contains a large amount of alpha-linolenic acids, there is abundant unsaturation in walnut oil
Aliphatic acid has the hypolipemic function that grease does not have, and is rich in abundant phosphatide in walnut oil, is that brain is essential heavy
Nutrient is wanted, there is distinguished brain-healthy effect nootropic effect part can be replaced to make grease needed for biscuit.
3. wormwood is bitter in taste, pungent, warm, enter spleen, liver and kidney channel.Energy dispelling cold and removing dampness, warming channel for arresting bleeding.Modern experimental research has shown that,
Folium artemisiae argyi has antibacterial and antivirus action, can enhance resistivity of the human body to disease.And wormwood is warm-natured, can effectively alleviate
Pueraria lobata it is cold；Dried orange peel, spleen benefiting and stimulating the appetite, herbal medicine is mitigated together with wormwood to react a few peoples' discomfort.Meanwhile the alkali of the two
Property can also reduce blood uric acid, help releasing symptom.
4. phenylpropanoids and flavone compound have preferably in isolated monomeric compound in perilla leaf
Xanthine oxidase inhibitory activity.
5. the Flavonoid substances in celery seed, mainly digicitrine and apiolin.Flavones in celery seed can be effective
Inhibit the generation of DPPH and hydroxy radical, there is stronger antioxidation, preservative can be replaced, it is without any side effects,
And it is more long that biscuit can be made to preserve.
6. the pure jujube powder of celery seed powder and part is directly edible by people in the form of being attached to biscuit surface, avoid baking high
Destruction of the temperature to fragrance and nutritional ingredient, pure jujube powder add celery seed powder make biscuit flavor is unique, mouthfeel is more preferable, it is functional more
It is good.
7. simple to operation.Finished product biscuit combines the celery seed of grease form and powder type in a manner of unique, tool
Have a stable function, fusion celery seed powder, pueraria lobata, wormwood, dried orange peel, perilla leaf multiple efficacies be suitable for various crowds to eat, have
Effective auxiliary treatment gout, anti-trioxypurine, QI invigorating cold dispelling, the advantages of keeping fit and healthy, and flavor be full, good for health while having again
There is unique strong fragrance, is conducive to improve a poor appetite.
Specific implementation mode
The present invention is described in further details with specific embodiment below, but the present invention is not only limited in detail below in fact
Apply example.
Embodiment 1
Weigh raw material：Wheat flour 600g, milk powder 160g, fresh milk 400g, sugar 10g, butter 10g, yeast powder 6g, honey 10g, celery
Rapeseed meal 2g, brown sugar 10g, pure jujube original powder 10g, Purple Perilla Seed Oil 10g, walnut oil 6g, wormwood 6g, dried orange peel 6g, pueraria lobata 6g, purple perilla
Leaf 6g；It is made by following procedure of processing：
(1) dried orange peel 6g is added into methanol 100mL, be heated to reflux 20 minutes, the filtrate of filtering, concentration filtrate obtains thick under vacuum
Medicinal extract is spray-dried to obtain dry extract, then is crushed to 60 mesh, obtains dried orange peel medicinal extract powder.
(2) pueraria lobata 6g and wormwood 6g are added water to cook secondary 2 hours every time, collecting decoction filters to get filtrate, under vacuum
Concentration filtrate obtains thick medicinal extract, is spray-dried to obtain dry extract, then be crushed to 60 mesh, obtains Chinese medical concrete powder.
(3) it takes perilla leaf 6g to add methanol 150mL, is ultrasonically treated 30min filtrations, the filtrate of filtering, under vacuum concentration filter
Liquid obtains thick medicinal extract, is spray-dried to obtain dry extract, then is crushed to 60 mesh, obtains perilla leaf medicinal extract powder.
(4) wheat flour 600g, milk powder 160g, fresh milk 400g, yeast powder 6g and water stir evenly in dough mixing machine, and at dough
And ferment, at 30 DEG C, fermentation time 6 hours adds dried orange peel medicinal extract prepared by sugared 10g, butter 10g, honey 10g, step (1)
Powder, the Chinese medical concrete powder of step (2) preparation, the perilla leaf medicinal extract powder of step (3) preparation, brown sugar 10g, pure jujube original powder
8g, Purple Perilla Seed Oil 10g, walnut oil 6g and suitable water stir evenly, and at dough, stand 20min；
(5) zhang dough is rolled to flour cake with making dough, goes out shape with various Biscuit mold coining, 200 DEG C of ovens are baked to ripe, obtain
Biscuit ontology, and the pure jujube original powders of remaining 2g, 2g celery seed powder are sprinkling upon the biscuit surface baked.
Embodiment 2
Weigh raw material：Wheat flour 800g, milk powder 180g, fresh milk 500g, sugar 12g, butter 12g, yeast powder 10g, honey 12g,
Celery seed powder 3g, brown sugar 12g, pure jujube original powder 12g, walnut oil 8g, Purple Perilla Seed Oil 12g, wormwood 8g, dried orange peel 8g, pueraria lobata 8g, purple
Perilla leaf 8g；It is made by following procedure of processing：
(1) dried orange peel 8g is added into methanol 150mL, be heated to reflux 20 minutes, the filtrate of filtering, concentration filtrate obtains thick under vacuum
Medicinal extract is spray-dried to obtain dry extract, then is crushed to 100 mesh, obtains dried orange peel medicinal extract powder.
(2) pueraria lobata 8g and wormwood 8g are added water to cook secondary 2 hours every time, collecting decoction filters to get filtrate, under vacuum
Concentration filtrate obtains thick medicinal extract, is spray-dried to obtain dry extract, then be crushed to 100 mesh, obtains Chinese medical concrete powder.
(3) it takes perilla leaf 8g to add methanol 200mL, is ultrasonically treated 30min filtrations, the filtrate of filtering, under vacuum concentration filter
Liquid obtains thick medicinal extract, is spray-dried to obtain dry extract, then is crushed to 100 mesh, obtains perilla leaf medicinal extract powder.
(4) wheat flour 800g, milk powder 180g, fresh milk 500g, yeast powder 10g and water stir evenly in dough mixing machine, and at face
It rolls into a ball and ferments, at 32 DEG C, fermentation time 10 hours adds dried orange peel prepared by sugared 12g, butter 12g, honey 12g, step (1)
Perilla leaf medicinal extract powder, brown sugar 12g, the pure jujube of Chinese medical concrete powder, step (3) preparation prepared by medicinal extract powder, step (2)
Original powder 8g, walnut oil 8g, Purple Perilla Seed Oil 12g and suitable water stir evenly, and stand 30min；
(5) zhang dough is rolled to flour cake with making dough, goes out shape with various Biscuit mold coining, 250 DEG C of ovens are baked to ripe, obtain
Biscuit ontology, and remaining pure jujube original powder 4g, celery seed powder 3g are sprinkling upon on the biscuit ontology baked.
Embodiment 3
(1) raw material is weighed：Wheat flour 700g, milk powder 170g, fresh milk 450g, sugar 20g, butter 11g, yeast powder 7g, honey
11g, celery seed powder 4g, brown sugar 11g, pure jujube original powder 11g, walnut oil 7g, Purple Perilla Seed Oil 11g, wormwood 7g, dried orange peel 7g, pueraria lobata
7g, perilla leaf 7g；
(2) dried orange peel is added into methanol 125mL, be heated to reflux 20 minutes, the filtrate of filtering, concentrated filtrate under vacuum and obtain thick leaching
Cream is spray-dried to obtain dry extract, then is crushed to 80 mesh, obtains dried orange peel medicinal extract powder.
(3) pueraria lobata and wormwood are added water to cook secondary 2 hours every time, collecting decoction filters to get filtrate, and concentrates under vacuum
Filtrate obtains thick medicinal extract, is spray-dried to obtain dry extract, then is crushed to 80 mesh, obtains Chinese medical concrete powder.
(4) take perilla leaf that methanol 175mL is added to be ultrasonically treated 30min filtrations, the filtrate of filtering concentrates filtrate and obtains under vacuum
Thick medicinal extract is spray-dried to obtain dry extract, then is crushed to 80 mesh, obtains perilla leaf medicinal extract powder.
(5) wheat flour, milk powder, fresh milk, yeast powder and water stir evenly in dough mixing machine, and at dough and ferment, at 30 DEG C
~32 DEG C, fermentation time 8 hours adds sugar, butter, honey, each medicinal extract powder, brown sugar, the pure jujube original powders of 9g, purple perilla seed
Oil, walnut oil and water stir, and dough is made, and stand 25min；
(6) zhang dough is rolled to flour cake with making dough, goes out shape with various Biscuit mold coining, 230 DEG C of ovens are baked to ripe, obtain
Biscuit, and pure jujube original powder 2g and celery seed powder are sprinkling upon on the biscuit surface baked.
The weight percent of each ingredient is obtained through repeatedly allotment is final in above example, not only unique in taste but also each
The blend proportion balanced and reasonable of ingredient, has effectively played the effect of each ingredient, after being especially combined, wormwood, pueraria lobata,
Dried orange peel, perilla leaf, celery seed powder and Fructus Perillae quintessence oil, each ingredient of walnut oil match each other and promote, and greatly improve auxiliary and control
Gout, oxidation resistant effect are treated, through most experiments number it was demonstrated that the attainable work(of institute after more individually various composition is respectively adopted in it
The summation of effect improves whole twice, also, character of the present invention is more mild, even if in the case that large amounts of food will not be to people
Body constitutes injury, can be used as daily bread long-term consumption.
Now by 3 scheme biscuit of embodiment 1- embodiments, do not add the biscuit of celery seed or any preservative and by celery seed
The biscuit for being exchanged with the preservatives such as sorbic acid, potassium sorbate, benzoic acid carries out contrast test, in 70% time 28 DEG C, relative humidity guarantor
It deposits, inoxidizability test is carried out to health-caring biscuit, the results are shown in Table 2
Table 2
As shown in Table 1, the health-caring biscuit that prepared by the present invention has stronger oxidation resistant effect, and it is anti-can to significantly improve biscuit
The rotten time.
3 embodiment of table, 1 product quality testing result
Explanation：It is GB/T 20980-2007 (similarly hereinafter) that quality inspection, which executes standard,.
4 embodiment of table, 2 product quality testing result
Explanation：It is GB/T 20980-2007 that quality inspection, which executes standard,.
3 product quality testing result of embodiment
Explanation：It is GB/T 20980-2007 that quality inspection, which executes standard,.
5 1~embodiment of embodiment of table, 3 Analyses Methods for Sensory Evaluation Results
| Embodiment | Evaluation number | Appearance acceptance % | Smell acceptance % | Mouthfeel acceptance % | Flavour acceptance % |
| Embodiment 1 | 50 | 98 | 96 | 95 | 96 |
| Embodiment 2 | 50 | 97 | 99 | 98 | 94 |
| Embodiment 3 | 50 | 95 | 87 | 96 | 97 |
As shown in table 5, the health-caring biscuit that 1~embodiment of embodiment 3 is obtained using the present invention, sensory modalities are good, appearance, gas
Taste, mouthfeel, flavour can be widely accepted.
6 Examples 1 to 3 Analysis of Nutritive Composition table of table
| Embodiment | Embodiment 1 | Embodiment 2 | Embodiment 3 |
| Protein g/100g | 20.1 | 18.0 | 17 |
| Water-soluble dietary fiber g/100g | 10 | 12 | 11 |
| Calcium mg/100g | 300 | 325 | 310 |
| Iron mg/100g | 4.5 | 4.7 | 4.6 |
| Selenium ug/100g | 10 | 12 | 10 |
| Zinc mg/100g | 4.37 | 4.63 | 4.14 |
| Vitamin A ug/100g | 245 | 238 | 235 |
| Vitamin D ug/100g | 1.8 | 1.7 | 2.0 |
| Vitamin B1 mg/100g | 0.29 | 0.32 | 0.30 |
| Vitamin B2 mg/100g | 0.34 | 0.42 | 0.38 |
| Vitamin B6 mg/100g | 0.26 | 0.3 | 0.27 |
| Niacin mg/100g | 3.50 | 3.69 | 3.58 |
The ratio of 7 1~embodiment of embodiment of table 3 nutritional ingredient and nutrient reference value (NRV)
| Embodiment | Embodiment 1 | Embodiment 2 | Embodiment 3 |
| Protein g/100g | 34 | 30 | 28 |
| Water-soluble dietary fiber g/100g | 40 | 48 | 44 |
| Calcium mg/100g | 38 | 41 | 39 |
| Iron mg/100g | 30 | 31 | 30 |
| Selenium ug/100g | 20 | 24 | 20 |
| Zinc mg/100g | 29 | 31 | 28 |
| Vitamin A ug/100g | 31 | 30 | 29 |
| Vitamin D ug/100g | 36 | 34 | 40 |
| Vitamin B1 mg/100g | 21 | 23 | 21 |
| Vitamin B2 mg/100g | 24 | 30 | 27 |
| Vitamin B6 mg/100g | 19 | 21 | 20 |
| Niacin mg/100g | 25 | 26 | 25 |
If 6~7 data of table can be seen that in the health-caring biscuit that 1~embodiment of the embodiment of the present invention 3 obtains, each nutrient
The ratio of nutrient reference value (NRV) is accounted between 19%~48%, rich content, and match more equilibrium and meet fortification
Requirement, can reach effectively and reasonably supplement the nutrients element purpose.
For treating the clinical efficacy of gout
1, case selection
1) meet primary urarthritis criteria for classification, while excluding acute gout arthritis；
2) age person between 18-70 Sui, male or female；
3) other anti-trioxypurine drugs are not taken and influence the drug of uric acid metabolism and excretion up to 1 week or more.
2, diagnostic criteria
It is promulgated using Chinese Medical Association in 2010《Clinic diagnosis guide rheumatism fascicle》In " Primary Gouty Arthritis point
Class standard "：
1. there is specific urate crystal in joint fluid, or 2. chemically or in the tophus of polarization microscope confirmation contain
There is urate crystal, or 3. has 6 in following 12 (clinic, laboratory, the performances of x lines):A. acute arthritis breaking-out is super
It crosses primary；B. inflammatory reaction reaches peak in one day；C. monarthritis is broken out；D. visible joint local redness；E. it first hesitates toe
Arthralgia or swelling；F. toe joint involvement is opened up in unilateral side first；G. unilateral side stagger Bones and joints involvement；H. suspicious tophus；I. high urine
Acidaemia；J. the intra-articular swelling of asymmetry (confirmation of x lines)；K. tumour is not accompanied by bone erosion (confirmation of x lines) under cortex of bone；L.
The culture of joint fluid is negative when arthritis is broken out；
With reference first to above-mentioned diagnostic criteria, patient diagnosed has gout, and increases (male and postmenopausal women with blood uric acid>
420umol/L, Pre-menopausal Women>350umol/L).Exclude acute gout arthritis simultaneously, i.e., 1. pain progressive aggravates,
Reach peak within 12 hours, it is difficult to endure:2. affected joints redness is scorching hot, function limitation, touches a tender spot all clearly.Note:Blood uric acid value
The 7th edition published with reference to people's health《Clinical practice》
3, curative effect determinate standard
It is evaluated using comprehensive therapeutic effect:(with reference to health ministry publication《New Chinese medicine guideline of clinical investigations》)
Clinical recovery:Arthralgia, tenderness, acute red and swollen, limitation of activity total mark decline 100%.
It is effective:Arthralgia, tenderness, acute red and swollen, limitation of activity total mark decline >=66%.
Effectively:Arthralgia, tenderness, acute red and swollen, limitation of activity total mark decline >=33% and ＜ 66%.
In vain:Arthralgia, tenderness, acute red and swollen, limitation of activity total mark decline<33%.
Note:Calculation formula (Nimodipine method):Integral reduces percentage=(one post treatment integral of prior treatment integral)/treatment foreset
Divide * 100%.
4, drug application method
Treatment group allopurinol tablet 0.05g, 2 times/day and daily one bag of the health-caring biscuit in the embodiment of the present invention；
Control group 1 allopurinol tablet 0.1g, 2 times/day；
Control group 2 allopurinol tablet 0.05g, 2 times/day；
March is treated altogether.
5, clinical effectiveness
There is the symptom of side effect reaction：(occur after medication following symptom be defined as medication side effect occur)
(1) gastrointestinal reaction：Such as Nausea and vomiting, loss of appetite.
(2) cutaneous anaphylaxis：Such as pruitus, fash.
(3) bone marrow suppression is reacted：Check that leucocyte and decrease of platelet etc. occurs in blood routine.
(4) hepatocellular damage：Liver function test is done, may occur in which that dysfunction of liver, predominantly transaminase increase, minority there can be Huang
Subcutaneous ulcer.Curative effect compares after two groups of treatments, is shown in Table 1.
1 two groups of pretherapy and post-treatment curative effects of table compare
| Group | Number of cases | Recovery from illness | It is effective | Effectively | In vain | It is efficient | Side effect number of cases | Side effect rate | Effective+cure rate |
| Treatment group | 20 | 4 | 11 | 5 | 1 | 95% | 2 | 10% | 75% |
| Control group 1 | 20 | 5 | 12 | 3 | 0 | 100% | 16 | 80% | 85% |
| Control group 2 | 20 | 1 | 6 | 8 | 5 | 75% | 4 | 20% | 35% |
As shown in Table 1, after using the health-caring biscuit auxiliary treatment of auxiliary treatment gout of the present invention 3 months, total effective rate up to 95%,
And effective plus cure rate will be significantly better than control group 2, side effect rate is significantly lower than two groups using allopurinol tablet.
Conclusion：The present invention treat gout biscuit can effective anti-trioxypurine, can assist reduce gout recur, alleviation gout
Shape.And have no toxic side effect, it is the natural functional food with health-care effect.
Using effect：
Tan, man, 61 years old, people from Shandong, in May, 2015 was medical, and repeated relapsing joint of lower extremity swells and ache more than 7 years, monthly sends out recently
Make about 2 times, 687 μm of ol/L of blood uric acid, through biscuit of embodiment of the present invention dietotherapy March, checks 307 μm of ol/L of blood uric acid, it is not multiple again
Hair.
Song, man, 55 years old, people from Dandong, 2 months 2016 medical, and joint of lower extremity swells and ache more than 9 years repeatedly, whole body many places gout
Stone, 642 μm of ol/L of blood uric acid check 310 μm of ol/L of blood uric acid, tophus part is molten through biscuit of embodiment of the present invention dietotherapy March
Solution, no relapse.
It these are only specific embodiments of the present invention, be not intended to restrict the invention, for those skilled in the art
For member, the invention may be variously modified and varied.Any modification made by all within the spirits and principles of the present invention,
Equivalent replacement, improvement etc., should all be included in the protection scope of the present invention.
Claims (1)
1. a kind of health-caring biscuit of auxiliary treatment gout, it is characterized in that：
The raw material of the health-caring biscuit includes：Wheat flour 600g-800g, milk powder 160g-180g, fresh milk 400g-500g, sugar
10g-20g, butter 10g-12g, yeast powder 6g-10g, honey 10g-12g, celery seed powder 2g-4g, brown sugar 10g-12g, jujube powder
10g-12g, walnut oil 6g-8g, Purple Perilla Seed Oil 10g-12g, wormwood 6g-8g, dried orange peel 6g-8g, pueraria lobata 6g-8g, perilla leaf 6g-
8g；
Its making includes the following steps：
(1) by dried orange peel, methanol 100mL-150mL is added to be heated to reflux 20 minutes, the filtrate of filtering concentrates filtrate under vacuum
Thick medicinal extract is obtained, dry extract is spray-dried to obtain, then be crushed to -100 mesh of 60 mesh, obtains dried orange peel medicinal extract powder；
(2) pueraria lobata and wormwood are added water to cook secondary 2 hours every time, collecting decoction filters to get filtrate, and concentrates under vacuum
Filtrate obtains thick medicinal extract, is spray-dried to obtain dry extract, then is crushed to -100 mesh of 60 mesh, obtains Chinese medical concrete powder；
(3) perilla leaf is taken, adds methanol 150mL-200mL to be ultrasonically treated 30 minutes and filters, the filtrate of filtering is dense under vacuum
Contracting filtrate obtains thick medicinal extract, is spray-dried to obtain dry extract, then is crushed to -100 mesh of 60 mesh, obtains perilla leaf medicinal extract powder；
(4) wheat flour, milk powder, fresh milk, yeast powder and water stir evenly in dough mixing machine, and at dough and ferment, 30 DEG C-
32 DEG C, fermentation time -10 hours 6 hours adds dried orange peel medicinal extract powder, step prepared by sugar, butter, honey, step (1)
(2) prepare Chinese medical concrete powder, step (3) prepare perilla leaf medicinal extract powder, brown sugar, 8g-10g jujube powders, Purple Perilla Seed Oil,
Walnut oil and water stir, and dough is made, and stand 20min-30min；
(5) zhang dough is rolled to flour cake with making dough, goes out shape with various Biscuit mold coining, 200 DEG C of -250 DEG C of ovens are baked to
It is ripe, biscuit is obtained, and celery seed powder, remaining jujube powder 2g-4g are sprinkling upon the biscuit surface baked.
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Cited By (1)
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| CN109045138A (en) * | 2018-09-26 | 2018-12-21 | 渤海大学 | A kind of compound celery seed tablet and preparation method thereof assisting in the treatment of gout |
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