CN108096506A - One kind is dispelled wart Chinese medicinal plant extracting solution and preparation method thereof - Google Patents

One kind is dispelled wart Chinese medicinal plant extracting solution and preparation method thereof Download PDF

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CN108096506A
CN108096506A CN201711497721.8A CN201711497721A CN108096506A CN 108096506 A CN108096506 A CN 108096506A CN 201711497721 A CN201711497721 A CN 201711497721A CN 108096506 A CN108096506 A CN 108096506A
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weight
parts
extracting solution
wart
chinese medicinal
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罗清山
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/90Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • A61K36/195Strobilanthes
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287Chrysanthemum, e.g. daisy
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315Isatis, e.g. Dyer's woad
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/536Prunella or Brunella (selfheal)
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/85Verbenaceae (Verbena family)
    • A61K36/855Clerodendrum, e.g. glorybower
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Abstract

It dispels wart Chinese medicinal plant extracting solution the present invention relates to one kind, the wart Chinese medicinal plant extracting solution of dispelling for primary raw material and carries out reasonable compatibility by using smilax, wild chrysanthemum, folium isatidis, selfheal, honeysuckle, safflower, Radix Glycyrrhizae, the coptis, Cortex Phellodendri, the root of bidentate achyranthes, purslane, kuh-seng, the fruit of summer cypress, the wart Chinese medicinal plant extracting solution of dispelling being prepared, each Chinese medicine is used cooperatively, it gives full play to it and cooperates with compatibility effect, clearing heat and detoxicating, the effect of dispelling wart of drawing out pus by applying a plaster to the affected part is played altogether, outer control can eradicate wart and eliminate incubation period wart, so as to achieve the purpose that radical cure, recurrence rate is extremely low;Also, wart Chinese medicinal plant extracting solution of the present invention of dispelling can promote skin health to grow, and adjust skin surface cell, disease damage skin is made to get well, and adjust skin immune function controlling, also have and soothe the skin surface layer, inhibit inflammatory cell, antibacterial toxin expelling effect.

Description

One kind is dispelled wart Chinese medicinal plant extracting solution and preparation method thereof
Technical field
The invention belongs to technical field of pharmaceuticals, and in particular to one kind is dispelled wart Chinese medicinal plant extracting solution and preparation method thereof.
Background technology
Skin benign neoplasm caused by flat wart, verruca vulgaris, plantar wart, condyloma acuminatum system human papilloma virus infection, Can direct contagion, also can indirect infection.The traditional Chinese medical science thinks that be qi-blood disharmony interspaces of skin and muscles being loose feels exopathogen again, and cohesion skin forms.West Doctor is considered that infecting human papilloma virus causes, it has important relationship with immune status, particularly cellular immunity defence Mechanism plays a major role.
Treating the relatively common method of this disease at present is:Cold therapy, laser therapy, fulguration treatment, operative treatment And aminolevulinic acid photodynamic therapy (ALA-PDT therapies), the above therapy, it typically takes from larger and multiple Hair rate is very high, and therapeutic effect is unsatisfactory.Drug therapy often has 0.5% podophyllotoxin tincture (or 0.15% frost), 5% imiquimod Frost, 80-90% trichloroacetic acids or dichloroacetic acid etc., although such treatment method is spent less, side effect is larger, and recurs Rate is very high, and therapeutic effect is also preferable not to the utmost.It is well known that the treatment of verrucosis, first, wart is dispelled, second is that anti-recurrence, wart It dispels and is easier, but recurrence is a problem.
The content of the invention
In order to solve the above problem existing in the prior art, the present invention provides it is a kind of it is safe to use, evident in efficacy, after The extremely low wart Chinese medicinal plant extracting solution and preparation method thereof of dispelling of recurrence rate.The wart Chinese medicinal plant extracting solution of dispelling to mycotic infection and Cervical erosion also has significant curative effect, and without obvious toxic-side effects.
The technical solution adopted in the present invention is:
One kind is dispelled wart Chinese medicinal plant extracting solution, and raw material components include:
Smilax extracting solution 12-18 parts by weight, wild chrysanthemum extracting solution 12-18 parts by weight, folium isatidis 5-12 parts by weight, summer are withered Careless 5-12 parts by weight, honeysuckle 5-12 parts by weight, safflower 2-8 parts by weight, Radix Glycyrrhizae 5-12 parts by weight, coptis 2-8 parts by weight, Cortex Phellodendri 2-8 parts by weight, root of bidentate achyranthes 2-8 parts by weight, purslane 5-12 parts by weight, Radix Sophorae Flavescentis extractive liquid 5-12 parts by weight, fruit of summer cypress 2-8 weight Part.
The raw material components of further preferably described wart Chinese medicinal plant extracting solution of dispelling include:
Smilax extracting solution 14-16 parts by weight, wild chrysanthemum extracting solution 14-16 parts by weight, folium isatidis 8-10 parts by weight, summer are withered Careless 8-10 parts by weight, honeysuckle 8-10 parts by weight, safflower 4-6 parts by weight, Radix Glycyrrhizae 8-10 parts by weight, coptis 4-6 parts by weight, Cortex Phellodendri 4-6 parts by weight, root of bidentate achyranthes 4-6 parts by weight, purslane 8-10 parts by weight, Radix Sophorae Flavescentis extractive liquid 8-10 parts by weight, fruit of summer cypress 4-6 weight Part.
The raw material components of further preferably described wart Chinese medicinal plant extracting solution of dispelling include:
15 parts by weight of smilax extracting solution, 15 parts by weight of wild chrysanthemum extracting solution, 9 parts by weight of folium isatidis, 9 weight of selfheal Part, 9 parts by weight of honeysuckle, 5 parts by weight of safflower, 9 parts by weight of Radix Glycyrrhizae, 5 parts by weight of the coptis, 5 parts by weight of Cortex Phellodendri, 5 parts by weight of the root of bidentate achyranthes, 9 parts by weight of purslane, 9 parts by weight of Radix Sophorae Flavescentis extractive liquid, 5 parts by weight of the fruit of summer cypress.
The smilax extracting solution is prepared with the following method:
(S1) fetch earth Poria cocos, after drying and crushing, obtains smilax fine powder;
(S2) the smilax fine powder is impregnated into 0.5-2h in water, heating decocts extraction 3 times, adds 15-20 times for the first time Water extracts 1-2h, and second plus 8-12 times of water extract 1-1.5h, third time plus 8-12 times of water, extract 0.5-1.5h, filter every time It crosses, merging filtrate, the volume concentration of filtrate is filtered to 3-7 times of smilax weight to obtain the final product.
The wild chrysanthemum extracting solution is prepared with the following method:
(SS1) wild chrysanthemum is taken, after drying and crushing, obtains wild chrysanthemum fine powder;
(SS2) the wild chrysanthemum fine powder is impregnated into 0.2-1h in ethanol solution, heating decocts extraction 3 times, adds for the first time 11-14 times of ethanol solution, extracts 1-2.5h, and second plus 9-11 times of ethanol solution extract 1-1.5h, third time plus 6-9 times of second Alcoholic solution extracts 0.5-1.5h, filters every time, merging filtrate, and the volume concentration of filtrate is filtered to 3-6 times of wild chrysanthemum weight To obtain the final product.
In step (SS2), the volume of the ethanol solution is 75%.
The Radix Sophorae Flavescentis extractive liquid is prepared with the following method:
(SSS1) kuh-seng is taken, after drying and crushing, obtains kuh-seng fine powder;
(SSS2) the kuh-seng fine powder is impregnated into 0.2-1h in ethanol solution, heating decocts extraction 3 times, adds for the first time 11-14 times of ethanol solution, extracts 1-2.5h, and second plus 9-11 times of ethanol solution extract 1-1.5h, third time plus 6-9 times of second Alcoholic solution extracts 0.5-1.5h, filters every time, merging filtrate, and the volume concentration of filtrate is filtered to 3-6 times of wild chrysanthemum weight To obtain the final product.
In step (SSS2), the volume of the ethanol solution is 75%.
The preparation method of the wart Chinese medicinal plant extracting solution of dispelling, includes the following steps:
(1) folium isatidis, selfheal, honeysuckle, safflower, Radix Glycyrrhizae, the coptis, Cortex Phellodendri, the root of bidentate achyranthes and purslane are taken respectively, through respectively After drying and crushing, each raw material fine powder is obtained;
(2) each raw material fine powder is sufficiently mixed uniformly, obtains mixed material;Into the mixed material plus water carries out After decoction, filtering obtains decoction liquor;
(3) decoction liquor is concentrated into relative density as 1.1-1.3, sequentially add afterwards the smilax extracting solution, Wild chrysanthemum extracting solution and Radix Sophorae Flavescentis extractive liquid are sufficiently mixed uniformly to get the wart Chinese medicinal plant extracting solution of dispelling.
In step (2), when carrying out the decoction, the mass ratio of water and mixed material is 2:1-8:1, carry out the decoction Time be 2-4h.
For the ease of understanding the present invention, the raw material in the present invention and drug effect are further elaborated below.
Smilax, it is sweet in flavor, light, it is mild-natured.Dehumidifying, removing toxic substances is easing joint movement.For damp and hot stranguria with turbid discharge, under band, carbuncle swells, scrofula, scabies Limbs contraction caused by tinea, syphilis and mercury poisoning, arthralgia and myalgia.
Wild chrysanthemum, bitter, pungent, cold nature.It is clearing heat and detoxicating.For furunculosis carbuncle swells, red eye, swell pain, dizziness of having a headache.
Folium isatidis, bitter are cold in nature.It is clearing heat and detoxicating, blood cooling and ecchymoses removing.It joins the army for warm heresy, unconsciousness due to high fever, spot dermexanthesis, Huang Subcutaneous ulcer, hot dysentery, mumps, larynx numbness, erysipelas, carbuncle swells.
Selfheal, acrid flavour, hardship are cold in nature.It relieves inflammation or internal heat, improving eyesight, dissipating bind, detumescence.For red eye, swell pain, mesh pearl nyctalgia, headache is dizzy It is dizzy, scrofula, goiter and tumor, acute mastitis swelling and pain;Thyroid Gland Swell, scrofula, the proliferation of mammary gland, hypertension.
Honeysuckle, it is sweet in flavor, it is cold in nature.It is clearing heat and detoxicating, wind-heat dissipating.For carbuncle swells furunculosis, larynx numbness, erysipelas, toxic-heat and blood stasis, wind Thermal sensation emits, warm disease heating.
Safflower, acrid flavour are warm-natured.Invigorate blood circulation, removing blood stasis and analgesics.Belong to the blood-activating and menstruation-regulating medicinal of drug for invigorating blood circulation and eliminating stasis subordinate classification.With Controlling through closing, dysmenorrhoea, lochia, abdominal mass and lump, injury from falling down, sore swell and ache curative etc..
Radix Glycyrrhizae, it is sweet in flavor, it is mild-natured.Invigorate the spleen and benefit qi, cough-relieving apophlegmatic, emergency analgesic therapy, mediation property of medicine.Treat weakness of the spleen and the stomach, middle gas Contraction suddenly has a pain, mitigates that drug is strong, antidote is malicious in deficiency, cough and asthma, skin sore, abdomen.Heat-clearing should give birth to use, and bowl spares is preferably processed With.
The coptis, bitter are cold in nature.Heat-clearing and damp-drying drug, purging intense heat and detonicating.With control damp and hot feeling of fullness, vomiting acid regurgitation, rush down dysentery, jaundice, high fever Coma, heart-fire hyperactivity, hot eyes, have a toothache, quench one's thirst, carbuncle swells furunculosis at blood-head tells nosebleed.Suitable amount used externally controls eczema, wet sore, duct and suppurates.
Cortex Phellodendri, bitter are cold in nature.Heat-clearing and damp-drying drug, purging intense heat, except steaming, detoxification sore treatment.With control damp-heat dysentery, jaundice, band under, heat Leaching, hectic fever due to yin labor heat, night sweat, seminal emission;Sore swollen toxin, eczema itch.
The root of bidentate achyranthes, bitter, acid are mild-natured.Filling liver kidney, strengthening the bones and muscles, are ensuringd proper downward flow of the blood at dispelling stasis of blood and stimulating the menstrual flow.With control soreness of waist and knee joint, muscles and bones without Power, Jing Bi Disorder lumps in the abdomen, dizziness due to hyperactivity of liver-YANG.
Purslane, it is sour, it is cold in nature.Clearing heat and detoxicating, cooling blood and hemostasis.With controlling enteritis, bacillary dysentery, furuncle swelling toxin, snakebite and bugbite, hemorrhoid Sore swells pain, eczema, acute dermatitis, subacute dermatitis, herpes zoster, postpartum and function temper official bleeding, appendicitis, hookworm disease.
Kuh-seng, bitter are cold in nature.Heat-clearing and damp-drying drug, desinsection, diuresis.For hot dysentery, have blood in stool, jaundice renal shutdown, leukorrhea with reddish discharge, the moon Swollen pruritus vulvae, eczema, wet sore, pruitus, mange leprosy;Control trichomonas vaginitis outside.
The fruit of summer cypress, it is sweet in flavor, bitter, it is cold in nature.It is eliminating dampness and heat, antipruritic.For pruitus, nettle rash, eczema, difficult urination.
Beneficial effects of the present invention are:
Wart Chinese medicinal plant extracting solution of the present invention of dispelling, by using smilax, wild chrysanthemum, folium isatidis, selfheal, gold Honeysuckle flower, safflower, Radix Glycyrrhizae, the coptis, Cortex Phellodendri, the root of bidentate achyranthes, purslane, kuh-seng, the fruit of summer cypress is primary raw materials and carry out reasonable compatibility, prepare Obtained wart Chinese medicinal plant extracting solution of dispelling, each Chinese medicine are used cooperatively, give full play to its cooperate with compatibility effect, play altogether it is clearing heat and detoxicating, It draws out pus by applying a plaster to the affected part the effect of dispelling wart, wart can be eradicated and eliminate incubation period wart by controlling outside, and so as to achieve the purpose that radical cure, recurrence rate is extremely low; Also, wart Chinese medicinal plant extracting solution of the present invention of dispelling can promote skin health to grow, and adjust skin surface cell, make disease damage Skin is got well, and adjusts skin immune function controlling, is also had and is soothed the skin surface layer, inhibits inflammatory cell, antibacterial toxin expelling effect.
Specific embodiment
To make the object, technical solutions and advantages of the present invention clearer, technical scheme will be carried out below Detailed description.Obviously, described embodiment is only part of the embodiment of the present invention, instead of all the embodiments.Base Embodiment in the present invention, those of ordinary skill in the art are obtained all on the premise of creative work is not made Other embodiment belongs to the scope that the present invention is protected.
In example below 1g is represented with 1 parts by weight.
Embodiment 1
It dispels wart Chinese medicinal plant extracting solution the present embodiment provides one kind, raw material components include:
12 parts by weight of smilax extracting solution, 18 parts by weight of wild chrysanthemum extracting solution, 5 parts by weight of folium isatidis, 12 weight of selfheal Part, 5 parts by weight of honeysuckle, 8 parts by weight of safflower, 5 parts by weight of Radix Glycyrrhizae, 8 parts by weight of the coptis, 2 parts by weight of Cortex Phellodendri, 8 parts by weight of the root of bidentate achyranthes, 5 parts by weight of purslane, 12 parts by weight of Radix Sophorae Flavescentis extractive liquid, 2 parts by weight of the fruit of summer cypress.
The smilax extracting solution is prepared with the following method:
(S1) fetch earth Poria cocos, after drying and crushing, obtains smilax fine powder;
(S2) the smilax fine powder is impregnated into 0.5h in water, heating decocts extraction 3 times, adds 15 times of water for the first time, carry 2h is taken, second plus 8 times of water extract 1.5h, third time plus 8 times of water, extract 1.5h, filter every time, merging filtrate, the body of filtrate Product is concentrated into 3 times of smilax weight, filters to obtain the final product.
The wild chrysanthemum extracting solution is prepared with the following method:
(SS1) wild chrysanthemum is taken, after drying and crushing, obtains wild chrysanthemum fine powder;
(SS2) the wild chrysanthemum fine powder is impregnated into 0.2h in volume fraction is 75% ethanol solution, heating decocts extraction 3 Secondary, for the first time plus 11 times of 75% ethanol solution, extraction 2.5h add 9 times of 75% ethanol solution for the second time, extract 1.5h, third time Add 6 times of 75% ethanol solution, extract 1.5h, filter every time, merging filtrate, 3 times of the volume concentration of filtrate to wild chrysanthemum weight, It filters to obtain the final product.
The Radix Sophorae Flavescentis extractive liquid is prepared with the following method:
(SSS1) kuh-seng is taken, after drying and crushing, obtains kuh-seng fine powder;
(SSS2) the kuh-seng fine powder is impregnated into 0.2h in volume fraction is 75% ethanol solution, heating decocts extraction 3 Secondary, for the first time plus 11 times of 75% ethanol solution, extraction 2.5h, second plus 9 times of ethanol solutions extract 1.5h, and third time adds 6 times 75% ethanol solution extracts 1.5h, filters every time, merging filtrate, and the volume concentration of filtrate is filtered to 3 times of wild chrysanthemum weight To obtain the final product.
Further the present embodiment provides the preparation method of the wart Chinese medicinal plant extracting solution of dispelling, include the following steps:
(1) folium isatidis, selfheal, honeysuckle, safflower, Radix Glycyrrhizae, the coptis, Cortex Phellodendri, the root of bidentate achyranthes and purslane are taken respectively, through respectively After drying and crushing, each raw material fine powder is obtained;
(2) each raw material fine powder is sufficiently mixed uniformly, obtains mixed material;Add 2 times of matter into the mixed material After amount water carries out decoction 4h, filtering obtains decoction liquor;
(3) it is 1.1 the decoction liquor to be concentrated into relative density, sequentially adds the smilax extracting solution, mother chrysanthemum afterwards Flower extracting solution and Radix Sophorae Flavescentis extractive liquid, are sufficiently mixed uniformly to get the wart Chinese medicinal plant extracting solution of dispelling.
Embodiment 2
It dispels wart Chinese medicinal plant extracting solution the present embodiment provides one kind, raw material components include:
18 parts by weight of smilax extracting solution, 12 parts by weight of wild chrysanthemum extracting solution, 12 parts by weight of folium isatidis, 5 weight of selfheal Part, 12 parts by weight of honeysuckle, 2 parts by weight of safflower, 12 parts by weight of Radix Glycyrrhizae, 2 parts by weight of the coptis, 8 parts by weight of Cortex Phellodendri, 2 weight of the root of bidentate achyranthes Part, 12 parts by weight of purslane, 5 parts by weight of Radix Sophorae Flavescentis extractive liquid, 8 parts by weight of the fruit of summer cypress.
The smilax extracting solution is prepared with the following method:
(S1) fetch earth Poria cocos, after drying and crushing, obtains smilax fine powder;
(S2) the smilax fine powder is impregnated into 2h in water, heating decocts extraction 3 times, adds 20 times of water, extraction for the first time 1h, second plus 12 times of water extract 1h, third time plus 12 times of water, extract 0.5h, filter every time, merging filtrate, the volume of filtrate It is concentrated into 7 times of smilax weight, filters to obtain the final product.
The wild chrysanthemum extracting solution is prepared with the following method:
(SS1) wild chrysanthemum is taken, after drying and crushing, obtains wild chrysanthemum fine powder;
(SS2) the wild chrysanthemum fine powder is impregnated into 1h in volume fraction is 75% ethanol solution, heating decocts extraction 3 Secondary, for the first time plus 14 times of 75% ethanol solution, extraction 1h, second plus 11 times of 75% ethanol solution extract 1h, and third time adds 9 Times 75% ethanol solution extracts 0.5h, filters every time, merging filtrate, and the volume concentration of filtrate is to 6 times of wild chrysanthemum weight, mistake It filters to obtain the final product.
The Radix Sophorae Flavescentis extractive liquid is prepared with the following method:
(SSS1) kuh-seng is taken, after drying and crushing, obtains kuh-seng fine powder;
(SSS2) the kuh-seng fine powder is impregnated into 1h in volume fraction is 75% ethanol solution, heating decocts extraction 3 times, For the first time plus 14 times of 75% ethanol solution, extraction 1h, second plus 11 times of ethanol solutions extract 1h, and third time adds 9 times of 75% second Alcoholic solution extracts 0.5h, filters every time, and merging filtrate, the volume concentration of filtrate is filtered to 6 times of wild chrysanthemum weight to obtain the final product.
Further the present embodiment provides the preparation method of the wart Chinese medicinal plant extracting solution of dispelling, include the following steps:
(1) folium isatidis, selfheal, honeysuckle, safflower, Radix Glycyrrhizae, the coptis, Cortex Phellodendri, the root of bidentate achyranthes and purslane are taken respectively, through respectively After drying and crushing, each raw material fine powder is obtained;
(2) each raw material fine powder is sufficiently mixed uniformly, obtains mixed material;Add 8 times of matter into the mixed material After amount water carries out decoction 2h, filtering obtains decoction liquor;
(3) it is 1.3 the decoction liquor to be concentrated into relative density, sequentially adds the smilax extracting solution, mother chrysanthemum afterwards Flower extracting solution and Radix Sophorae Flavescentis extractive liquid, are sufficiently mixed uniformly to get the wart Chinese medicinal plant extracting solution of dispelling.
Embodiment 3
It dispels wart Chinese medicinal plant extracting solution the present embodiment provides one kind, raw material components include:
16 parts by weight of smilax extracting solution, 14 parts by weight of wild chrysanthemum extracting solution, 10 parts by weight of folium isatidis, 8 weight of selfheal Part, 10 parts by weight of honeysuckle, 4 parts by weight of safflower, 10 parts by weight of Radix Glycyrrhizae, 4 parts by weight of the coptis, 6 parts by weight of Cortex Phellodendri, 4 weight of the root of bidentate achyranthes Part, 10 parts by weight of purslane, 8 parts by weight of Radix Sophorae Flavescentis extractive liquid, 6 parts by weight of the fruit of summer cypress.
The smilax extracting solution is prepared with the following method:
(S1) fetch earth Poria cocos, after drying and crushing, obtains smilax fine powder;
(S2) the smilax fine powder is impregnated into 1.2h in water, heating decocts extraction 3 times, adds 17 times of water for the first time, carry 1.5h is taken, second plus 10 times of water extract 1.2h, third time plus 10 times of water, extract 1h, filter every time, merging filtrate, filtrate Volume concentration is filtered to 5 times of smilax weight to obtain the final product.
The wild chrysanthemum extracting solution is prepared with the following method:
(SS1) wild chrysanthemum is taken, after drying and crushing, obtains wild chrysanthemum fine powder;
(SS2) the wild chrysanthemum fine powder is impregnated into 0.6h in volume fraction is 75% ethanol solution, heating decocts extraction 3 Secondary, for the first time plus 12 times of 75% ethanol solution, extraction 1.2h add 10 times of 75% ethanol solution for the second time, extract 1.2h, third time Add 7 times of 75% ethanol solution, extract 1h, filter every time, merging filtrate, the volume concentration of filtrate is to 4 times of wild chrysanthemum weight, mistake It filters to obtain the final product.
The Radix Sophorae Flavescentis extractive liquid is prepared with the following method:
(SSS1) kuh-seng is taken, after drying and crushing, obtains kuh-seng fine powder;
(SSS2) the kuh-seng fine powder is impregnated into 0.6h in volume fraction is 75% ethanol solution, heating decocts extraction 3 Secondary, for the first time plus 13 times of 75% ethanol solution, extraction 1.7h, second plus 10 times of ethanol solutions extract 1.2h, and third time adds 15 75% ethanol solution again extracts 1h, filters every time, merging filtrate, and the volume concentration of filtrate is filtered to 4 times of wild chrysanthemum weight To obtain the final product.
Further the present embodiment provides the preparation method of the wart Chinese medicinal plant extracting solution of dispelling, include the following steps:
(1) folium isatidis, selfheal, honeysuckle, safflower, Radix Glycyrrhizae, the coptis, Cortex Phellodendri, the root of bidentate achyranthes and purslane are taken respectively, through respectively After drying and crushing, each raw material fine powder is obtained;
(2) each raw material fine powder is sufficiently mixed uniformly, obtains mixed material;Add 5 times of matter into the mixed material After amount water carries out decoction 3h, filtering obtains decoction liquor;
(3) it is 1.2 the decoction liquor to be concentrated into relative density, sequentially adds the smilax extracting solution, mother chrysanthemum afterwards Flower extracting solution and Radix Sophorae Flavescentis extractive liquid, are sufficiently mixed uniformly to get the wart Chinese medicinal plant extracting solution of dispelling.
Embodiment 4
It dispels wart Chinese medicinal plant extracting solution the present embodiment provides one kind, raw material components include:
14 parts by weight of smilax extracting solution, 16 parts by weight of wild chrysanthemum extracting solution, 8 parts by weight of folium isatidis, 10 weight of selfheal Part, 8 parts by weight of honeysuckle, 6 parts by weight of safflower, 8 parts by weight of Radix Glycyrrhizae, 6 parts by weight of the coptis, 4 parts by weight of Cortex Phellodendri, 6 parts by weight of the root of bidentate achyranthes, 8 parts by weight of purslane, 10 parts by weight of Radix Sophorae Flavescentis extractive liquid, 4 parts by weight of the fruit of summer cypress.
The smilax extracting solution is prepared with the following method:
(S1) fetch earth Poria cocos, after drying and crushing, obtains smilax fine powder;
(S2) the smilax fine powder is impregnated into 1.2h in water, heating decocts extraction 3 times, adds 22 times of water for the first time, carry 1.5h is taken, second plus 10 times of water extract 1.2h, third time plus 10 times of water, extract 1h, filter every time, merging filtrate, filtrate Volume concentration is filtered to 5 times of smilax weight to obtain the final product.
The wild chrysanthemum extracting solution is prepared with the following method:
(SS1) wild chrysanthemum is taken, after drying and crushing, obtains wild chrysanthemum fine powder;
(SS2) the wild chrysanthemum fine powder is impregnated into 0.6h in volume fraction is 75% ethanol solution, heating decocts extraction 3 Secondary, for the first time plus 12 times of 75% ethanol solution, extraction 1.7h add 10 times of 75% ethanol solution for the second time, extract 1.2h, third time Add 7 times of 75% ethanol solution, extract 1h, filter every time, merging filtrate, the volume concentration of filtrate is to 4 times of wild chrysanthemum weight, mistake It filters to obtain the final product.
The Radix Sophorae Flavescentis extractive liquid is prepared with the following method:
(SSS1) kuh-seng is taken, after drying and crushing, obtains kuh-seng fine powder;
(SSS2) the kuh-seng fine powder is impregnated into 0.6h in volume fraction is 75% ethanol solution, heating decocts extraction 3 Secondary, for the first time plus 12 times of 75% ethanol solution, extraction 1.7h, second plus 10 times of ethanol solutions extract 1.2h, and third time adds 7 75% ethanol solution again extracts 1h, filters every time, merging filtrate, and the volume concentration of filtrate is filtered to 4 times of wild chrysanthemum weight To obtain the final product.
Further the present embodiment provides the preparation method of the wart Chinese medicinal plant extracting solution of dispelling, include the following steps:
(1) folium isatidis, selfheal, honeysuckle, safflower, Radix Glycyrrhizae, the coptis, Cortex Phellodendri, the root of bidentate achyranthes and purslane are taken respectively, through respectively After drying and crushing, each raw material fine powder is obtained;
(2) each raw material fine powder is sufficiently mixed uniformly, obtains mixed material;Add 5 times of matter into the mixed material After amount water carries out decoction 3h, filtering obtains decoction liquor;
(3) it is 1.2 the decoction liquor to be concentrated into relative density, sequentially adds the smilax extracting solution, mother chrysanthemum afterwards Flower extracting solution and Radix Sophorae Flavescentis extractive liquid, are sufficiently mixed uniformly to get the wart Chinese medicinal plant extracting solution of dispelling.
Embodiment 5
It dispels wart Chinese medicinal plant extracting solution the present embodiment provides one kind, raw material components include:
15 parts by weight of smilax extracting solution, 15 parts by weight of wild chrysanthemum extracting solution, 9 parts by weight of folium isatidis, 9 weight of selfheal Part, 9 parts by weight of honeysuckle, 5 parts by weight of safflower, 9 parts by weight of Radix Glycyrrhizae, 5 parts by weight of the coptis, 5 parts by weight of Cortex Phellodendri, 5 parts by weight of the root of bidentate achyranthes, 9 parts by weight of purslane, 9 parts by weight of Radix Sophorae Flavescentis extractive liquid, 5 parts by weight of the fruit of summer cypress.
The smilax extracting solution is prepared with the following method:
(S1) fetch earth Poria cocos, after drying and crushing, obtains smilax fine powder;
(S2) the smilax fine powder is impregnated into 1.2h in water, heating decocts extraction 3 times, adds 7 times of water, extraction for the first time 1.5h, second plus 10 times of water extract 1.2h, third time plus 10 times of water, extract 1h, filter every time, merging filtrate, the body of filtrate Product is concentrated into 5 times of smilax weight, filters to obtain the final product.
The wild chrysanthemum extracting solution is prepared with the following method:
(SS1) wild chrysanthemum is taken, after drying and crushing, obtains wild chrysanthemum fine powder;
(SS2) the wild chrysanthemum fine powder is impregnated into 0.6h in volume fraction is 75% ethanol solution, heating decocts extraction 3 Secondary, for the first time plus 12 times of 75% ethanol solution, extraction 1.2h add 10 times of 75% ethanol solution for the second time, extract 1.2h, third time Add 7 times of 75% ethanol solution, extract 1h, filter every time, merging filtrate, the volume concentration of filtrate is to 4 times of wild chrysanthemum weight, mistake It filters to obtain the final product.
The Radix Sophorae Flavescentis extractive liquid is prepared with the following method:
(SSS1) kuh-seng is taken, after drying and crushing, obtains kuh-seng fine powder;
(SSS2) the kuh-seng fine powder is impregnated into 0.6h in volume fraction is 75% ethanol solution, heating decocts extraction 3 Secondary, for the first time plus 12 times of 75% ethanol solution, extraction 1.7h, second plus 10 times of ethanol solutions extract 1.2h, and third time adds 7 75% ethanol solution again extracts 1h, filters every time, merging filtrate, and the volume concentration of filtrate is filtered to 4 times of wild chrysanthemum weight To obtain the final product.
Further the present embodiment provides the preparation method of the wart Chinese medicinal plant extracting solution of dispelling, include the following steps:
(1) folium isatidis, selfheal, honeysuckle, safflower, Radix Glycyrrhizae, the coptis, Cortex Phellodendri, the root of bidentate achyranthes and purslane are taken respectively, through respectively After drying and crushing, each raw material fine powder is obtained;
(2) each raw material fine powder is sufficiently mixed uniformly, obtains mixed material;Add 5 times of matter into the mixed material After amount water carries out decoction 3h, filtering obtains decoction liquor;
(3) it is 1.2 the decoction liquor to be concentrated into relative density, sequentially adds the smilax extracting solution, mother chrysanthemum afterwards Flower extracting solution and Radix Sophorae Flavescentis extractive liquid, are sufficiently mixed uniformly to get the wart Chinese medicinal plant extracting solution of dispelling.
The above description is merely a specific embodiment, but protection scope of the present invention is not limited thereto, any Those familiar with the art in the technical scope disclosed by the present invention, can readily occur in change or replacement, should all contain Lid is within protection scope of the present invention.Therefore, protection scope of the present invention should be based on the protection scope of the described claims.

Claims (10)

  1. The wart Chinese medicinal plant extracting solution 1. one kind is dispelled, which is characterized in that raw material components include:
    Smilax extracting solution 12-18 parts by weight, wild chrysanthemum extracting solution 12-18 parts by weight, folium isatidis 5-12 parts by weight, selfheal 5- 12 parts by weight, honeysuckle 5-12 parts by weight, safflower 2-8 parts by weight, Radix Glycyrrhizae 5-12 parts by weight, coptis 2-8 parts by weight, Cortex Phellodendri 2-8 Parts by weight, root of bidentate achyranthes 2-8 parts by weight, purslane 5-12 parts by weight, Radix Sophorae Flavescentis extractive liquid 5-12 parts by weight, fruit of summer cypress 2-8 parts by weight.
  2. 2. wart Chinese medicinal plant extracting solution according to claim 1 of dispelling, which is characterized in that raw material components include:
    Smilax extracting solution 14-16 parts by weight, wild chrysanthemum extracting solution 14-16 parts by weight, folium isatidis 8-10 parts by weight, selfheal 8- 10 parts by weight, honeysuckle 8-10 parts by weight, safflower 4-6 parts by weight, Radix Glycyrrhizae 8-10 parts by weight, coptis 4-6 parts by weight, Cortex Phellodendri 4-6 Parts by weight, root of bidentate achyranthes 4-6 parts by weight, purslane 8-10 parts by weight, Radix Sophorae Flavescentis extractive liquid 8-10 parts by weight, fruit of summer cypress 4-6 parts by weight.
  3. 3. wart Chinese medicinal plant extracting solution according to claim 1 of dispelling, which is characterized in that raw material components include:
    15 parts by weight of smilax extracting solution, 15 parts by weight of wild chrysanthemum extracting solution, 9 parts by weight of folium isatidis, 9 parts by weight of selfheal, gold 9 parts by weight of honeysuckle flower, 5 parts by weight of safflower, 9 parts by weight of Radix Glycyrrhizae, 5 parts by weight of the coptis, 5 parts by weight of Cortex Phellodendri, 5 parts by weight of the root of bidentate achyranthes, dent 9 parts by weight of amaranth, 9 parts by weight of Radix Sophorae Flavescentis extractive liquid, 5 parts by weight of the fruit of summer cypress.
  4. 4. wart Chinese medicinal plant extracting solution according to claim 1 of dispelling, which is characterized in that the smilax extracting solution is using such as Lower section method is prepared:
    (S1) fetch earth Poria cocos, after drying and crushing, obtains smilax fine powder;
    (S2) the smilax fine powder is impregnated into 0.5-2h in water, heating decocts extraction 3 times, adds 15-20 times of water for the first time, carry 1-2h is taken, second plus 8-12 times of water extract 1-1.5h, third time plus 8-12 times of water, extract 0.5-1.5h, filter every time, close And filtrate, the volume concentration of filtrate are filtered to 3-7 times of smilax weight to obtain the final product.
  5. 5. wart Chinese medicinal plant extracting solution according to claim 1 of dispelling, which is characterized in that the wild chrysanthemum extracting solution is using such as Lower section method is prepared:
    (SS1) wild chrysanthemum is taken, after drying and crushing, obtains wild chrysanthemum fine powder;
    (SS2) the wild chrysanthemum fine powder is impregnated into 0.2-1h in ethanol solution, heating decocts extraction 3 times, adds 11-14 for the first time Times ethanol solution extracts 1-2.5h, and second plus 9-11 times of ethanol solution extract 1-1.5h, and third time plus 6-9 times of ethyl alcohol are molten Liquid extracts 0.5-1.5h, filters every time, and merging filtrate, the volume concentration of filtrate is filtered to 3-6 times of wild chrysanthemum weight to obtain the final product.
  6. 6. wart Chinese medicinal plant extracting solution according to claim 1 of dispelling, which is characterized in that in step (SS2), the ethyl alcohol is molten The volume of liquid is 75%.
  7. 7. wart Chinese medicinal plant extracting solution according to claim 1 of dispelling, which is characterized in that the Radix Sophorae Flavescentis extractive liquid is using as follows Method is prepared:
    (SSS1) kuh-seng is taken, after drying and crushing, obtains kuh-seng fine powder;
    (SSS2) the kuh-seng fine powder is impregnated into 0.2-1h in ethanol solution, heating decocts extraction 3 times, adds 11-14 for the first time Times ethanol solution extracts 1-2.5h, and second plus 9-11 times of ethanol solution extract 1-1.5h, and third time plus 6-9 times of ethyl alcohol are molten Liquid extracts 0.5-1.5h, filters every time, and merging filtrate, the volume concentration of filtrate is filtered to 3-6 times of wild chrysanthemum weight to obtain the final product.
  8. 8. wart Chinese medicinal plant extracting solution according to claim 1 of dispelling, which is characterized in that in step (SSS2), the ethyl alcohol The volume of solution is 75%.
  9. 9. the preparation method for wart Chinese medicinal plant extracting solution of dispelling described in claim any one of 1-8, which is characterized in that including walking as follows Suddenly:
    (1) folium isatidis, selfheal, honeysuckle, safflower, Radix Glycyrrhizae, the coptis, Cortex Phellodendri, the root of bidentate achyranthes and purslane are taken respectively, through being separately dried After crushing, each raw material fine powder is obtained;
    (2) each raw material fine powder is sufficiently mixed uniformly, obtains mixed material;Into the mixed material plus water is decocted Afterwards, filter, obtain decoction liquor;
    (3) decoction liquor is concentrated into relative density as 1.1-1.3, sequentially adds the smilax extracting solution, mother chrysanthemum afterwards Flower extracting solution and Radix Sophorae Flavescentis extractive liquid, are sufficiently mixed uniformly to get the wart Chinese medicinal plant extracting solution of dispelling.
  10. 10. the preparation method for wart Chinese medicinal plant extracting solution of dispelling according to claim 9, which is characterized in that in step (2), into During the row decoction, the mass ratio of water and mixed material is 2:1-8:1, the time for carrying out the decoction is 2-4h.
CN201711497721.8A 2017-12-29 2017-12-29 One kind is dispelled wart Chinese medicinal plant extracting solution and preparation method thereof Pending CN108096506A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112402521A (en) * 2019-08-22 2021-02-26 梁德权 Traditional Chinese medicine formula for treating wart skin diseases and preparation method thereof
CN113041328A (en) * 2021-04-20 2021-06-29 相慧敏 HPV wart removing soup

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Publication number Priority date Publication date Assignee Title
CN1201676A (en) * 1997-06-09 1998-12-16 李香兰 Cosmetical face film with Chinese medicines
KR20140048908A (en) * 2014-03-05 2014-04-24 바이오이퀄 아게 Topical formulation to be applied to wart removal, nail-disease treatment and nail care

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Publication number Priority date Publication date Assignee Title
CN1201676A (en) * 1997-06-09 1998-12-16 李香兰 Cosmetical face film with Chinese medicines
KR20140048908A (en) * 2014-03-05 2014-04-24 바이오이퀄 아게 Topical formulation to be applied to wart removal, nail-disease treatment and nail care

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112402521A (en) * 2019-08-22 2021-02-26 梁德权 Traditional Chinese medicine formula for treating wart skin diseases and preparation method thereof
CN113041328A (en) * 2021-04-20 2021-06-29 相慧敏 HPV wart removing soup

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