CN103316146A - Traditional Chinese medicinal preparation for anesthesia - Google Patents

Abstract

The invention discloses a traditional Chinese medicine preparation for anesthesia. The raw materials of the active ingredients of the traditional Chinese medicine preparation are keel, wild jujube seed, acacia bark, mandala, celestia chinensis, seven peristae, chuanwu, grass aconitum, cloves and chicken droppings Rattan, Danpi, Eucommia, Indigo Daisy, Fenugreek, Honeysuckle, and Atractylodes macrocephala; the traditional Chinese medicine preparation of the present invention is composed of multi-flavored medicinal materials, and has quick effect, short duration, high anesthesia efficiency, strong controllability during operation, and recovery after operation The advantage of being fast, the anesthetic drug can be metabolized and excreted in time after the operation, and has good curative effect against complications caused by anesthesia; the traditional Chinese medicine preparation of the present invention also has obvious analgesic effect and anti-shock effect.

Description

A kind of traditional Chinese medicine preparation for anesthesia

technical field

The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine preparation for anesthesia.

Background technique

In clinical operations, anesthesia is a variety of methods used to eliminate pain, ensure patient safety, and create good surgical conditions during operations or diagnostic inspections. A patient who feels pain during a surgical or diagnostic test and needs anesthesia or other means to temporarily lose consciousness. Surgery or inspection operations can also cause mental stress and reflex adverse reactions, such as gastrointestinal surgery can cause nausea and vomiting. Long-term uncomfortable positions (such as prone position) can increase the patient's discomfort and pain. Therefore, the patient should be operated in a comfortable and quiet environment without responding to adverse stimuli and temporarily losing memory.

At present, injection of procaine or conduction block is generally used for anesthesia or topical anesthesia through patch. The existing anesthesia methods are relatively cumbersome to operate, and also have anesthesia risks. Therefore, be badly in need of a kind of Chinese medicinal preparation for anesthesia to implement local anesthesia better on the market.

Contents of the invention

The invention provides a traditional Chinese medicine preparation for anesthesia, which is a pure Chinese medicine preparation made of multi-flavor medicinal materials, and has the advantages of quick effect, short duration, high anesthesia efficiency, strong controllability during operation, and quick recovery after operation. The anesthesia drug can be metabolized and excreted in time after the operation, and has a good curative effect against complications caused by anesthesia; the traditional Chinese medicine preparation of the invention also has obvious analgesic effect and anti-shock effect.

To achieve the above object, the implementation of the technical solution of the present invention is as follows:

A traditional Chinese medicine preparation for anesthesia, the raw material composition and parts by weight of the active ingredients of the Chinese medicine preparation are:

30-70 parts of keel;

26-62 parts of Tianxianzi, 25-60 parts of Qilizi, 24-58 parts of Chuanwu, 23-56 parts of Caowu

22-54 parts of cloves, 21-52 parts of chicken dung vine, 20-50 parts of paeonol, 19-48 parts of Eucommia

Qingdai 18-46 parts, Fenugreek 17-45 parts, Honeysuckle 16-42 parts, Atractylodes macrocephala 15-40 parts.

The raw material composition and the parts by weight of making described Chinese medicine preparation active ingredient are:

33-67 parts of keel, 32-65 parts of jujube seed, 31-63 parts of Albizia jujuba, 30-61 parts of Datura

29-59 parts of Tianxianzi, 28-57 parts of Qilizi, 27-55 parts of Chuanwu, 26-53 parts of Caowu

25-51 parts of cloves, 24-49 parts of chicken dung vine, 23-47 parts of paeonol, 22-45 parts of Eucommia

Qingdai 21-44 parts, Fenugreek 20-42 parts, Honeysuckle 19-39 parts, Atractylodes macrocephala 18-37 parts.

The raw material composition and the parts by weight of making described Chinese medicine preparation active ingredient are:

37-63 parts of keel, 35-61 parts of jujube seed, 33-59 parts of Albizia jujuba, 32-57 parts of Datura

32-55 parts of Tianxianzi, 30-53 parts of Qilizi, 29-51 parts of Chuanwu, 28-50 parts of Caowu

27-48 parts of cloves, 26-45 parts of chicken dung vine, 25-44 parts of paeonol, 24-42 parts of Eucommia

Qingdai 23~41 parts, Fenugreek 22~39 parts, Honeysuckle 21~36 parts, Atractylodes macrocephala 20~34 parts.

The raw material composition and the parts by weight of making described Chinese medicine preparation active ingredient are:

50 parts of keel, 48 parts of wild jujube seed, 46 parts of acacia skin, 45 parts of Datura

44 parts of Tianxianzi, 42 parts of Qilizi, 40 parts of Chuanwu, 39 parts of Caowu

37 parts of clove, 35 parts of chicken dung vine, 34 parts of paeonol, 32 parts of Eucommia

Qingdai 31 parts, Fenugreek 29 parts, Honeysuckle 28 parts, Atractylodes macrocephala 26 parts.

A preparation method of traditional Chinese medicine preparation for anesthesia, the preparation steps are as follows:

(1) Boil keel, angelica, seven peristae, chuanwu, clove, paeonol, eucommia, fenugreek, and honeysuckle with distilled water for 3 times, add 6-10 times the amount of distilled water for the first time to soak for 3-4 hours, heat and boil Extract for 2-3 hours; add 3-5 times the amount of distilled water for the second time, heat and boil for extraction for 1-2 hours, add 2-3 times the amount of distilled water for the third time, heat and boil for 0.5-1 hour, combine the extracts, and filter to obtain The filtrate is concentrated into a dry extract for subsequent use;

(2) Add the dry extract obtained in step (1) into a 90% ethanol solution by volume, let it stand overnight, extract the supernatant, and set aside the precipitated extract;

(3) Grind the jujube seed into powder, pass through 200 mesh fine powder, soak the powder in water for 1~2 hours, filter, and take the solution for later use;

(4) Remove the ash and dust from the acacia skin, soak it in wine, wash it, take it out, dry it, grind it into powder, and set it aside;

(5) Rinse Atractylodes macrocephala, Indigo Daisy, Aconiti officinalis, Chrysanthemum officinale, and Datura 5 traditional Chinese medicines, dry them in microwave, grind them into 200 meshes, add 75% ethanol solution at 70-90°C and heat reflux to extract 1.5 -2 hours, filter off the medicinal residues, concentrate into an extract and save for later use;

(6) Mix the extract obtained in step (2) and step (5), and then mix the solution obtained in step (3) and the powder obtained in step (4) to form the traditional Chinese medicine preparation for anesthesia.

The property of medicine of Chinese medicine used in the present invention is as follows:

Keel: sweet, astringent, flat. Condensing Qi and expelling dampness, stopping night sweats, calming the nerves, astringent essence to stop bleeding. Treatment of convulsions and epilepsy, palpitations and forgetfulness, insomnia and dreaminess, spontaneous sweating, nocturnal emission and stranguria, vomiting blood in the stool, uterine bleeding, dysentery and prolapse of the anus, ulcers that do not close for a long time. The keel has the effects of calming the nerves and calming the nerves, astringing sweat and solidifying essence, stopping bleeding and puckering the intestines, promoting muscle growth and astringing sores. "Bie Lu" contains: "Dragon bones are used to treat confidant and fullness, atrophy of limbs, sweating, self-consciousness when lying down at night, anger, breathlessness under the heart, intestinal ulcers, internal gangrene, eczema, antiperspirant, narrowing of stools, and blood in the urine. , nourish the spirit, stabilize the soul."

Suanzaoren: sweet, flat. Nourishes the liver, calms the heart, soothes the nerves, and suppresses sweat. Control insomnia due to deficiency, palpitation with distress, polydipsia, sweating due to debility. "Materia Medica Zaixin" contains: "calming the liver and regulating qi, moistening the lungs and nourishing yin, warming the middle and promoting dampness, restraining qi and stopping sweating, benefiting the mind and calming down, improving ears and eyesight."

Cortex Albiziae: neutral in nature, sweet in taste; non-toxic; GUIXIN, Liver Meridian. It has the effects of relieving depression and calming the nerves, promoting blood circulation and reducing swelling. It has the functions of relieving depression, harmonizing blood, calming the heart, and eliminating carbuncle. Treatment of restlessness, depression, insomnia, lung abscess, sores, and pain from falls. "Compendium" contains: "harmonize blood, reduce swelling, relieve pain."

Datura: pungent in taste, warm in nature, and highly poisonous. Flowers can remove rheumatism, relieve asthma and relieve pain, and can cure convulsions, epilepsy and cold asthma. Decoction and washing can cure all wind stubborn numbness and cold-damp beriberi. The analgesic effect of petals is excellent, and it can cure neuralgia and so on. Datura has the functions of antispasmodic, sedative, analgesic and anesthetic.

Tianxianzi: bitter, warm, poisonous. Determining epilepsy, relieving pain. Cure mania, wind epilepsy, wind arthralgia Jue pain, neuralgia, wheezing and coughing, stomach pain, chronic dysentery, chronic diarrhea, proctoptosis, toothache, carbuncle, malignant sore. "Supplements to Materia Medica" contains: "mainly obsessive, eliminate evil and chase wind."

Qilizi: slightly warm in nature, pungent and bitter in taste. Suppressing liver and relieving stagnation, promoting blood circulation and expelling wind, improving eyesight, and relieving itching. For headache and dizziness, distending pain in the chest and hypochondria, mastitis, red eyes and nebula, rubella and itching.

Chuanwu: pungent, bitter, hot in nature, poisonous; Guixin, liver, kidney, spleen meridian. Expelling wind and removing dampness, warming meridians to relieve pain, used for anemofrigid-damp arthralgia, arthralgia, trusted subordinates cold pain, colic caused by cold, anesthesia for pain relief. According to the "Pearl Sac Supplementary Drug Nature Fu": "Dispel the cold evil of all winds; break the cold pain of all accumulations." Modern medical research has confirmed that aconitine contained in Aconitum aconitum has an analgesic effect and can paralyze peripheral nerves when used externally. Peripherals produce local anesthesia, analgesia and anti-inflammatory effects.

Aconitum: acrid, bitter. Expelling wind and removing dampness, warming meridian and relieving pain. For anemofrigid-damp arthralgia, arthralgia, confidant cold pain, cold colic pain, pain relief.

Clove: acrid in the mouth, warm in nature. Regulating qi and lowering adverse reactions, warming middle-JIAO and relieving pain, warming kidney. Indications of cold pain in the abdomen, hiccups, nausea, vomiting; impotence due to deficiency of kidney yang, and cold-damp leukorrhea and other diseases. "Compendium of Materia Medica" contains: "Clove treats kidney qi, rushes porpoise qi, yin pain, abdominal pain, aphrodisiac, warms waist and knees." Clove has the effects of anti-oxidation, scavenging free radicals and preventing hair loss.

Gallus chinensis: sweet and sour, flat. Expelling wind and activating blood circulation, relieving pain and detoxification, eliminating food stagnation, removing dampness and reducing swelling. Control rheumatic pain, diarrhea and dysentery, dirty abdominal pain, qi deficiency and edema, dizziness and lack of food, hepatosplenomegaly, scrofula, intestinal fistula, unknown swollen poison, traumatic injury. "Shanghai Commonly Used Chinese Herbal Medicine" contains: "Expelling wind, promoting blood circulation, relieving pain, and reducing swelling. Treat rheumatism, pain, bruises, hepatosplenomegaly, and nameless swelling."

Cortex paeonol: cold in nature, bitter in taste; cool; slightly cold. Return liver, kidney, lung meridian. Clearing away heat and cooling blood; promoting blood circulation and dispelling stasis. "Compendium of Materia Medica" contains: "Nourishing yin and reducing fire, detoxifying spots, benefiting throat, clearing blood stasis in urination. Later generations use yellow tiller to treat phase fire, but they don't know that the power of paeonol is better. The red flower is beneficial, and the white flower is beneficial. It is rare for people to understand it, so it should be separated.” Modern research shows that paeonol contained in paeonol and other glycoside components have anti-inflammatory effects; the methanol extract of paeonol has the effect of inhibiting platelets; paeonol has sedative, Cooling, antipyretic, analgesic, antispasmodic and other central inhibitory effects and anti-atherosclerosis, diuretic, anti-ulcer effects.

Eucommia ulmoides: sweet in taste, slightly pungent, warm in nature; enters liver meridian, kidney meridian. Invigorate liver and kidney, strengthen muscles and bones. Cure mainly lumbar spine pain, rheumatic arthralgia. According to "Emergency Prescriptions for Emergencies": "Functions: dispelling rheumatism, relieving numbness and pain, nourishing the liver and kidney, replenishing qi and blood, feeling wind-cold dampness, cold pain in the waist and knees, difficulty in flexion and extension of limb joints, or numbness, chills and warmth. "Modern medical research has confirmed that Eucommia has a calming effect on the nerve center, can enhance the immune function of cells, promote the secretion of cortisol and the metabolism of cAMP and cGMP in plasma.

Indigo Daisy: heat-clearing and toxic substances removing, cooling blood, calming convulsion. It is used for warming and poisoning spots, vomiting blood heat, chest pain and hemoptysis, aphtha, mumps, sore throat, infantile convulsion and epilepsy.

Fenugreek: bitter, warm. Tonifying kidney yang, dispelling cold and damp. Cure cold hernia, abdominal fullness, cold-damp beriberi, kidney deficiency and backache, impotence. "Jiayou Materia Medica" contains: "The main element is cold air due to deficiency of viscera. Obtain aconite and sulfur to treat kidney deficiency and cold, fullness in the abdomen and flanks, and dark complexion; obtain fennel seeds and peach kernels to cure bladder qi."

Honeysuckle: sweet in taste, slightly bitter, delicate fragrance, pungent in nature, cold; return lung, stomach, heart, large intestine meridian. It has been known as a good medicine for clearing away heat and detoxifying since ancient times. It is sweet and cold in nature and fragrant, sweet and cold to clear away heat without hurting the stomach, and the fragrance is thorough and can dispel evil. Honeysuckle can not only disperse wind-heat, but also clear and detoxify blood. It is used for various febrile and sexually transmitted diseases, and the effect is remarkable. "Jishantang Experience Prescription" contains: "Half a bowl of honeysuckle natural juice, decoct it for eight minutes and take it, apply it with dregs, detoxify the tori, disperse qi and blood, and its merits are unique." The effect of dispelling heat and evil, has a certain effect on exogenous wind-heat or febrile disease at the onset, body heat, headache, upset and less sleepiness, dizziness, crimson tongue, dry throat and mouth.

Atractylodes macrocephala: sweet, bitter, warm in nature. Invigorate the spleen, harmonize neutralization, dry dampness, and promote diuresis. Indications for weak temper, mental fatigue, internal cessation of drinking water, difficulty urinating, and edema.

Compared with the prior art, the present invention has the following beneficial effects:

The traditional Chinese medicine preparation of the present invention is composed of multi-flavor medicinal materials, and has the advantages of quick effect, short duration, high anesthesia efficiency, strong controllability during operation, quick recovery after operation, and can metabolize and excrete anesthetic drugs in time after operation. It has good curative effect against complications caused by anesthesia; the traditional Chinese medicine preparation of the invention also has obvious analgesic effect and anti-shock effect.

Detailed ways

The present invention is further supplemented below in conjunction with specific examples, but the present invention is not limited in any way.

Example 1

The raw material composition and the weight of Chinese medicine preparation active ingredient of the present invention are:

keel 50g jujube seed 48g acacia skin 46g mandala 45g

Tianxianzi 44g Qilizi 42g Chuanwu 40g Caowu 39g

Clove 37g Chicken Shit Vine 35g Danpi 34g Eucommia 32g

Qingdai 31g, Fenugreek 29g, Honeysuckle 28g, Atractylodes macrocephala 26g.

A preparation method of traditional Chinese medicine preparation for anesthesia, the preparation steps are as follows:

(1) Boil keel, angelica, seven peristae, chuanwu, clove, paeonol, eucommia, fenugreek, and honeysuckle with distilled water for 3 times, add 6-10 times the amount of distilled water for the first time to soak for 3-4 hours, heat and boil Extract for 2-3 hours; add 3-5 times the amount of distilled water for the second time, heat and boil for 1-2 hours, and add 2-3 times for the third time

Double the amount of distilled water, heat and boil to extract for 0.5-1 hour, combine the extracts, filter to obtain the filtrate, concentrate it into a dry extract for later use;

(2) Add the dry extract obtained in step (1) into a 90% ethanol solution by volume, let it stand overnight, extract the supernatant, and set aside the precipitated extract;

(3) Grind the jujube seed into powder, pass through 200 mesh fine powder, soak the powder in water for 1~2 hours, filter, and take the solution for later use;

(4) Remove the ash and dust from the acacia skin, soak it in wine, wash it, take it out, dry it, grind it into powder, and set it aside;

(5) Rinse Atractylodes macrocephala, Indigo Daisy, Aconiti officinalis, Chrysanthemum officinale, and Datura 5 traditional Chinese medicines, dry them in microwave, grind them into 200 meshes, add 75% ethanol solution at 70-90°C and heat reflux to extract 1.5 -2 hours, filter off the medicinal residues, concentrate into an extract and save for later use;

(6) Mix the extract obtained in step (2) with step (5), and then mix the solution obtained in step (3) with the powder obtained in step (4) to form the traditional Chinese medicine anesthesia preparation.

Dosage: Oral administration, 1 tablet at a time, 10 minutes before surgery.

Example 2

The raw material composition and the weight of Chinese medicine preparation active ingredient of the present invention are:

keel 39g jujube seed 37g acacia skin 35g mandala 34g

Tianxianzi 34g Qilizi 32g Chuanwu 31g Caowu 30g

29g of cloves, 28g of vines, 27g of paeonol, 26g of Eucommia

Qingdai 25g, Fenugreek 24g, Honeysuckle 23g, Atractylodes macrocephala 22g.

The preparation method of the traditional Chinese medicine preparation of the present embodiment is the same as the embodiment 1 in terms of process steps, usage and dosage.

Example 3

The raw material composition and the weight of Chinese medicine preparation active ingredient of the present invention are:

keel 35g jujube seed 34g acacia skin 33g mandala 32g

Tianxianzi 31g Qilizi 30g Chuanwu 29g Caowu 28g

27g of cloves, 26g of vines, 25g of paeonol, 24g of Eucommia

Qingdai 23g, Fenugreek 22g, Honeysuckle 21g, Atractylodes macrocephala 20g.

The preparation method of the traditional Chinese medicine preparation of the present embodiment is the same as the embodiment 1 in terms of process steps, usage and dosage.

Example 4

The raw material composition and the weight of Chinese medicine preparation active ingredient of the present invention are:

keel 32g jujube seed 31g acacia skin 30g mandala 29g

Tianxianzi 28g Qilizi 27g Chuanwu 26g Caowu 25g

24g of cloves, 23g of vines, 22g of paeonol, 21g of Eucommia

Qingdai 20g, Fenugreek 19g, Honeysuckle 18g, Atractylodes macrocephala 17g.

The preparation method of the traditional Chinese medicine preparation of the present embodiment is the same as the embodiment 1 in terms of process steps, usage and dosage.

clinical information:

The traditional Chinese medicine preparation of the present invention has been clinically observed in 100 cases of patients, and the effective rate of the traditional Chinese medicinal preparation of the present invention is remarkable. During the clinical observation process, the efficacy is definite, and no adverse reaction or allergic reaction is found in the patient.

treatment method:

Oral administration, 1 tablet at a time, 10 minutes before surgery. Calculate the anesthesia time according to the severity of the patient's condition, take 1 tablet for short-term and minor surgery patients, and 2 tablets for long-term and major surgery patients.

Efficacy Judgment Criteria:

(1) Significant effect: no pain during the operation;

(2) Effective: There is a sense of pain relief during the operation;

(3) Invalid: There is no pain relief during the operation.

Treatment results:

After taking the traditional Chinese medicine preparation of the present invention through clinical observation, 75 cases were markedly effective, 22 cases were effective, and 3 cases were ineffective. The total effective rate was 97%, which fully reached the standard for clinical use.

The traditional Chinese medicine preparation of the present invention is composed of multi-flavor medicinal materials, and has the advantages of quick effect, short duration, high anesthesia efficiency, strong controllability during operation, quick recovery after operation, and can metabolize and excrete anesthetic drugs in time after operation. It has good curative effect against complications caused by anesthesia; the traditional Chinese medicine preparation of the invention also has obvious analgesic effect and anti-shock effect.

Claims (5)

1. anesthesia Chinese medicine preparation is characterized in that: the raw material of making described Chinese medicine preparation effective ingredient forms and parts by weight are:

27～64 parts of 28～66 portions of Flos Daturae of 29～68 portions of Cortex Albiziaes of 30～70 parts of Semen Ziziphi Spinosaes of Os Draconis

23～56 parts of 24～58 portions of Radix Aconiti Kusnezoffii of Semen Hyoscyami 25～60 portions of Radix Aconitis of 26～62 parts of seven lis of sons

19～48 parts of 20～50 parts of Cortexs Eucommiae of 21～52 parts of Cortex Moutans of 22～54 parts of Herba Paederiaes of Flos Caryophylli

15～40 parts of 16～42 parts of Rhizoma Atractylodis Macrocephalaes of 17～45 portions of Flos Loniceraes of 18～46 parts of Semen Trigonellaes of Indigo Naturalis.

2. a kind of anesthesia Chinese medicine preparation according to claim 1 is characterized in that: the raw material of making described Chinese medicine preparation effective ingredient forms and parts by weight are:

30～61 parts of 31～63 portions of Flos Daturae of 32～65 portions of Cortex Albiziaes of 33～67 parts of Semen Ziziphi Spinosaes of Os Draconis

26～53 parts of 27～55 portions of Radix Aconiti Kusnezoffii of Semen Hyoscyami 28～57 portions of Radix Aconitis of 29～59 parts of seven lis of sons

22～45 parts of 23～47 parts of Cortexs Eucommiae of 24～49 parts of Cortex Moutans of 25～51 parts of Herba Paederiaes of Flos Caryophylli

18～37 parts of 19～39 parts of Rhizoma Atractylodis Macrocephalaes of 20～42 portions of Flos Loniceraes of 21～44 parts of Semen Trigonellaes of Indigo Naturalis.

3. a kind of anesthesia Chinese medicine preparation according to claim 1 is characterized in that: the raw material of making described Chinese medicine preparation effective ingredient forms and parts by weight are:

32～57 parts of 33～59 portions of Flos Daturae of 35～61 portions of Cortex Albiziaes of 37～63 parts of Semen Ziziphi Spinosaes of Os Draconis

28～50 parts of 29～51 portions of Radix Aconiti Kusnezoffii of Semen Hyoscyami 30～53 portions of Radix Aconitis of 32～55 parts of seven lis of sons

24～42 parts of 25～44 parts of Cortexs Eucommiae of 26～45 parts of Cortex Moutans of 27～48 parts of Herba Paederiaes of Flos Caryophylli

20～34 parts of 21～36 parts of Rhizoma Atractylodis Macrocephalaes of 22～39 portions of Flos Loniceraes of 23～41 parts of Semen Trigonellaes of Indigo Naturalis.

4. a kind of anesthesia Chinese medicine preparation according to claim 1 is characterized in that: the raw material of making described Chinese medicine preparation effective ingredient forms and parts by weight are:

45 parts of 46 portions of Flos Daturae of 48 portions of Cortex Albiziaes of 50 parts of Semen Ziziphi Spinosaes of Os Draconis

39 parts of 40 portions of Radix Aconiti Kusnezoffii of Semen Hyoscyami 42 portions of Radix Aconitis of 44 parts of seven lis of sons

32 parts of 34 parts of Cortexs Eucommiae of 35 parts of Cortex Moutans of 37 parts of Herba Paederiaes of Flos Caryophylli

26 parts of 28 parts of Rhizoma Atractylodis Macrocephalaes of 29 portions of Flos Loniceraes of 31 parts of Semen Trigonellaes of Indigo Naturalis.

One kind such as claim 1-4 anesthesia is with the preparation method of Chinese medicine preparation as described in each, it is characterized in that: preparation process is as follows:

(1) Os Draconis, Semen Hyoscyami, seven lis of sons, Radix Aconiti, Flos Caryophylli, Cortex Moutan, the Cortex Eucommiae, Semen Trigonellae, Flos Lonicerae adding distil waters are boiled and extract 3 times, add first 6-10 and doubly measured distilled water immersion 3-4 hour, heated and boiled was extracted 2-3 hour; Add for the second time 3-5 and doubly measure distilled water heated and boiled extraction 1-2 hour, add for the third time 2-3 and doubly measure distilled water heated and boiled extraction 0.5-1 hour, merge extractive liquid, filters, and gets filtrate, is condensed into dry extract for subsequent use;

(2) gained dry extract in the step (1) being added volumetric concentration is 90% alcoholic solution, and standing over night extracts supernatant, and the extractum that precipitates is for subsequent use;

(3) Semen Ziziphi Spinosae is ground into powder, crossed 200 order fine powders, powder was soaked 1 ~ 2 hour, filter, get solution for standby;

(4) with Cortex Albiziae dedust bits, soak with wine, clean, take out, dry, be crushed into powder, for subsequent use;

(5) Rhizoma Atractylodis Macrocephalae, Indigo Naturalis, Radix Aconiti Kusnezoffii, Herba Paederiae, Flos Daturae 5 flavor cflushes are clean, microwave drying, pulverizing are 200 orders, add volumetric concentration and are 75% alcoholic solution and extracted 1.5-2 hour in 70-90 ℃ of hot reflux, the elimination medicinal residues are condensed into extractum and save backup;

(6) with step (2) with after the extractum that makes in the step (5) mixes again and the solution of step (3) gained mix with the powder of step (4) gained, described anesthesia Chinese medicine preparation.