CN108079044A - The estrualization agent that a kind of breeding season sow uses - Google Patents
The estrualization agent that a kind of breeding season sow uses Download PDFInfo
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- CN108079044A CN108079044A CN201810089733.5A CN201810089733A CN108079044A CN 108079044 A CN108079044 A CN 108079044A CN 201810089733 A CN201810089733 A CN 201810089733A CN 108079044 A CN108079044 A CN 108079044A
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- Prior art keywords
- siraitia grosvenorii
- sow
- extraction
- breeding season
- estrualization
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/02—Breeding vertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Environmental Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Alternative & Traditional Medicine (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Chemical & Material Sciences (AREA)
- Medicines Containing Plant Substances (AREA)
- Fodder In General (AREA)
Abstract
The invention discloses the estrualization agents that a kind of breeding season sow uses, and are prepared by the following preparation method：1) feedstock processing：By fresh prematurity Siraitia grosvenorii, the Siraitia grosvenorii to drop, the villus on removal Siraitia grosvenorii surface；2) Subcritical Water Extraction：The raw material that upper step is obtained, is smashed, the deionized water of the weight such as addition, progress Subcritical Water Extraction, 120 150 DEG C of Extracting temperature, 5 8MPa of pressure, 10 15min of extraction time, and extraction terminates, and extract liquor is collected in pressure release；3) filter：By the extract liquor that upper step obtains by 0.45 μm of filtering, it is sealed, obtains.
Description
Technical field
The invention belongs to the estrualization agents that pig cultural technique field more particularly to a kind of breeding season sow use.
Background technology
The breeding of sow, the target with inter-species kind are bred in due course with the sow of body condition with herd boar with meeting with health
To improve pregnancy rate, the daily management for sow of weaning should focus on heat stimulation.After wean, breast can be swollen due to galactosis
It bulges and, when galactopoiesis keeps balance with reabsorbing, suckling process will taper off.After wean 2-3 days, breast is swollen
Swollen reduction, celluar tissue start to decompose, while FSH (follicular stimulating hormone) stimulates Oocyte Development folliculus ovarii is tough into ovarian follicle
Band will quickly increase and start to secrete estrogen, prepare to receive fertilized eggs for uterus, and stimulate performance symptom of estrus,
Estrogen can promote the secretion of LH (lutropin), and LH can make follicular development into ovum, and accelerate to ovulate.This stage is boar
The important stage of management, effective breeding just determine farrowing as a result, wean influences farrowing index to breeding interval, also influence
Litter size.The management of gestation and nursery phase has a major impact wean to the interval of breeding of sow.With pig cultural technique
It continuously improves, pig-breeding structure is just towards scale, intensive, specialized aquaculture model is fast-developing.Wherein, litter size
It is the important indicator for weighing sow reproductive performance, improves sow the first-born litter size, helps to improve the lifelong breeding achievement of sow.
Pig farm sow is when being bred at present, since the heat situation of wean sow is poor or breeding means are unreasonable
And other reasons so that first breeding or unsuccessful for the breeding again of Suprapubic arch sling, long-term nonpregnant sow proportion
Greatly, added cost is fed, there are larger economic losses, and additionally, due to that cannot breed in time, the farrowing rate on pig farm can be subject to very
Big to influence, economic benefit is difficult to improve, so as to be unfavorable for the development on pig farm.
It is presently used for before breeding in the daily ration of sow nurturing period, energy level and source can significantly affect the first feelings of sow
The quality of phase startup, Oestrus rate and egg mother cell.It has been investigated that high-energy level remarkably promotes Insulin, IGF- in blood
The secretion of 1 and Leptin increases the secretion frequency of LH, so as to improve the Oestrus rate of sow and ovulation rate, therefore, increases in daily ration
Add fat content that can improve triglyceride and total cholesterol concentration in blood, and E2 is promoted to secrete, be conducive to sow puberty
Start；And increase content of starch, as energy level improves, large follicle number increases, and IGF-1, E2 concentration raise in liquor folliculi, then
Be conducive to the maturation of egg mother cell.
Same reason, for the sow of breeding season, a kind of estrualization agent that can greatly transfer oestrus of sow stimulation of exploitation,
Or method of promoting the sexual maturity, it is successfully bred to primiparity and Suprapubic arch sling, improves the pregnancy rate of sow namely becoming pregnant to life for sow
Pig production has conclusive influence, and the pregnancy rate for how further improving sow is significant.
The content of the invention
It is an object of the present invention to provide the estrualization agent that a kind of breeding season sow uses, by increasing the secretion of Gilt Uterus, adjusting
Internal reproductive hormone secretion is saved, the cyclostage of sow is adjusted, promotees its heat.
The invention is realized by the following technical scheme：
The estrualization agent that a kind of breeding season sow uses, is prepared by the following preparation method：
1) feedstock processing：By fresh prematurity Siraitia grosvenorii, the Siraitia grosvenorii to drop, the villus on removal Siraitia grosvenorii surface；
2) Subcritical Water Extraction：The raw material that upper step is obtained, is smashed, and the deionized water of the weight such as addition carries out subcritical
Water extracts, 120-150 DEG C of Extracting temperature, pressure 5-8MPa, extraction time 10-15min, and extraction terminates, pressure release, collects extraction
Liquid；
3) filter：By the extract liquor that upper step obtains by 0.45 μm of filtering, it is sealed, obtains.
The villus on the removal Siraitia grosvenorii surface described in step 1) of the present invention, preferably by way of polishing or wiping.
Smashing described in step 1), it is below 0.5mm preferably to smash to grain size.
The estrualization agent that the breeding season sow that the present invention obtains uses, when in use, timing every morning warm water is to sow
Body surface and vaginal orifice are cleaned, and are dried after cleaning, input the breeding season sow of 30-40mL to Gilt Uterus using inseminating syringe daily
The estrualization agent used.
Compared with prior art, the advantage of the invention is that：
1st, the estrualization agent that the breeding season sow obtained using the present invention is used by oestrus sow, makes first farrowing sow, wean
Sow heat as early as possible, can effectively improve the Oestrus rate with broad sow.
2nd, Siraitia grosvenorii is the Special plant in Guilin, and there is substantial amounts of plantation on Guilin periphery.The fruit of Siraitia grosvenorii and and Ye Junhan
There is Siraitia grosvenorii triterpenoid saponin, also have substantial amounts of fructose, more than ten kinds of essential amino acid, aliphatic acid, flavone compound, dimension life
Plain C, trace element etc. can cause substantial amounts of shedding, not in the planting process of Siraitia grosvenorii because weather reason, pest and disease damage etc.
Mellow fruit etc., usually this part fruit can fall as offal treatment.The present invention passes through the utilization to this part Siraitia grosvenorii, a side
Face adds the benefit of Siraitia grosvenorii farmer, and on the other hand by the use of Siraitia grosvenorii as the feed addictive of pig raising, effect is fine.And
And the present invention is by the Subcritical Water Extraction to Siraitia grosvenorii, and compared to the extraction of heating water or alcohol extracting, under subcritical state, with
The rise of temperature, the hydrogen bond of subcritical water are opened or weaken, and are extracted so that water is high to Low, can thus pass through control
The temperature and pressure of subcritical water processed makes the polarity of water in interior variation in a big way, so as to fulfill effective components from natural materials
Continuous extraction from water soluble ingredient to liposoluble constituent, and can realize selective extraction, retaining Siraitia grosvenorii active ingredient
Meanwhile irritating fruit green grass or young crops taste that new fresh fructus momordicae is carried can be effectively removed, prevention smell has an impact pig.
3rd, now some researches show that, Siraitia grosvenorii too sweet tea, the easy impairment of the spleens.Siraitia grosvenorii such as with the sun dry can on behalf of the tea,
It but cannot be for a long time for tea.It can get angry if the drink of drying is more, cough due to wind-heat evil's preferably drink or with other heat-clearing cooling materials less
It drinks, nocturnal emission, enuresis nocturna person avoid, and drink in a short time harmless, and long-term drinking can cause the decline of gastrointestinal function, cause chain pathology
Reaction.These drawbacks of Siraitia grosvenorii are drawbacks to human body, equally, if as feed or feed addictive, can also influence pig
Stomach, Long-term Feeding can bring the gastro-intestinal problems of sow.The prior art, the use to Siraitia grosvenorii are mostly with reference to other plant
Either Chinese medicine is used directly as feed or feed addictive, and the present invention is compared using immature Siraitia grosvenorii, shedding
Mellow fruit, simply sweetener component therein is greatly reduced, but other nutritional ingredients still remain, and is directly to make
For the uterus of sow, this drawback of ripe Siraitia grosvenorii is just avoided, pig is can effectively prevent and gastro-intestinal problems occurs.
4th, ripe Siraitia grosvenorii, can dense yellowish-brown villus and mixed raw black glandular scale, villus be animal and plant for it is warming,
The Functional tissue resist the enemy, without nutrition, villus is easily sheltered evil people and countenance evil practices (bacterium, mould, birds droppings, frass, pesticide etc.) and posted for itself
Infested, microbial growth good carrier.The study found that the microorganism of the every gram of enrichment in fresh fructus momordicae surface layer is up to millions of,
It is very big to human health risk.The prior art also has the research by the use of Siraitia grosvenorii as feed, but the prior art is usually to adopt
Used by the use of the Siraitia grosvenorii of the Siraitia grosvenorii of fresh mature after either drying as raw material, the villus of Siraitia grosvenorii and it is untreated or
Person's processing is clean, and when the villus of Siraitia grosvenorii is with estrualization agent is machined into, the germ or microorganism that villus carries can not be complete
It is complete to kill, the uterus of sow can be seriously affected, and it is of the invention, in process engineering, the villus of Siraitia grosvenorii is specially removed, is effectively kept away
This problem is exempted from.
Specific embodiment
By the following examples with comparative example to further detailed description of the invention.But these embodiments are not considered as
Limitation of the present invention.
Embodiment 1：
The estrualization agent that a kind of breeding season sow uses, is prepared by the following preparation method：
1) feedstock processing：By fresh prematurity Siraitia grosvenorii, the Siraitia grosvenorii to drop, the suede on polishing removal Siraitia grosvenorii surface
Hair；
2) Subcritical Water Extraction：The raw material that upper step is obtained, it is going for the weight such as below 0.5mm, addition to smash to grain size
Ionized water carries out Subcritical Water Extraction, 120-150 DEG C of Extracting temperature, pressure 5-8MPa, extraction time 10-15min, extraction knot
Extract liquor is collected in beam, pressure release；
3) filter：By the extract liquor that upper step obtains by 0.45 μm of filtering, it is sealed, obtains.
Embodiment 2：
The estrualization agent that a kind of breeding season sow uses, is prepared by the following preparation method：
1) feedstock processing：By fresh prematurity Siraitia grosvenorii, the Siraitia grosvenorii to drop, the suede on erasing removal Siraitia grosvenorii surface
Hair；
2) Subcritical Water Extraction：The raw material that upper step is obtained, it is going for the weight such as below 0.5mm, addition to smash to grain size
Ionized water carries out Subcritical Water Extraction, 120-150 DEG C of Extracting temperature, pressure 5-8MPa, extraction time 10-15min, extraction knot
Extract liquor is collected in beam, pressure release；
3) filter：By the extract liquor that upper step obtains by 0.45 μm of filtering, it is sealed, obtains.
Comparative example 1：
Using fresh mature Siraitia grosvenorii as raw material.Other are the same as embodiment 1.
Comparative example 2：
It heats water extraction and replaces Subcritical Water Extraction, other are the same as embodiment 1.
Control group：
Conventinal breeding.
Experimental example：
The estrualization agent that the breeding season sow of the present invention uses, feeding experiment, feed (weight are carried out on our company pig farm respectively
Percentage)：Corn 30%, dregs of beans 25%, fish meal 25%, wheat bran 13%, brown sugar 4%, vegetable oil 2%, multi-vitamins 1%.
Conclusion：The estrualization agent that breeding season sow using the present invention uses can effectively improve the Oestrus rate of sow before breeding,
It improves average number born alive and piglet is averaged Birth weight, meanwhile, it can effectively prevent pig and vaginitis occur.
The present invention has also been contrast experiment in early period for the Subcritical Water Extraction extraction of prematurity Siraitia grosvenorii, uses 130-
140 DEG C of temperature range, than 120-150 DEG C temperature range of effect still have gap, and analysis is the extraction because temperature range is wide
Substance out is more, more meets and matches somebody with somebody the characteristics of broad sow nutritional need is big.
Claims (4)
1. the estrualization agent that a kind of breeding season sow uses, which is characterized in that be prepared by the following preparation method：
1) feedstock processing：By fresh prematurity Siraitia grosvenorii, the Siraitia grosvenorii to drop, the villus on removal Siraitia grosvenorii surface；
2) Subcritical Water Extraction：The raw material that upper step is obtained, is smashed, and the deionized water of the weight such as addition carries out subcritical water extraction
It takes, 120-150 DEG C of Extracting temperature, pressure 5-8MPa, extraction time 10-15min, extraction terminates, pressure release, collects extract liquor；
3) filter：By the extract liquor that upper step obtains by 0.45 μm of filtering, it is sealed, obtains.
2. the estrualization agent that a kind of breeding season sow according to claim 1 uses, it is characterised in that：It is gone described in step 1)
It is by way of polishing or wiping except the villus on Siraitia grosvenorii surface.
3. the estrualization agent that a kind of breeding season sow according to claim 1 uses, it is characterised in that：Beating described in step 1)
It is broken, be smash to grain size be below 0.5mm.
4. the estrualization agent that a kind of breeding season sow according to claim 1 uses, it is characterised in that：When in use, daily
Morning, timing cleaned sow body surface and vaginal orifice with warm water, was dried after cleaning, defeated to Gilt Uterus using inseminating syringe daily
Enter the estrualization agent that the breeding season sow of 30-40mL uses.
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| CN1947544A (en) * | 2006-09-18 | 2007-04-18 | 阜新红日牧业有限公司 | Forage for sow with functions of promoting sexual maturity fetus-care and health-care |
| CN106359268A (en) * | 2016-08-30 | 2017-02-01 | 界首市颖南万福家庭农场 | Method for cultivating sow in mating period |
| CN106666149A (en) * | 2016-12-30 | 2017-05-17 | 中悦民安（北京）科技发展有限公司 | Estrus and pregnancy promoting premixed feed for lactating sow and preparation method of estrus and pregnancy promoting premixed feed |
| CN107087485A (en) * | 2017-04-25 | 2017-08-25 | 龙胜裕丰农业发展有限公司 | A kind of tomato non-pollution implantation methods |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1947544A (en) * | 2006-09-18 | 2007-04-18 | 阜新红日牧业有限公司 | Forage for sow with functions of promoting sexual maturity fetus-care and health-care |
| CN106359268A (en) * | 2016-08-30 | 2017-02-01 | 界首市颖南万福家庭农场 | Method for cultivating sow in mating period |
| CN106666149A (en) * | 2016-12-30 | 2017-05-17 | 中悦民安（北京）科技发展有限公司 | Estrus and pregnancy promoting premixed feed for lactating sow and preparation method of estrus and pregnancy promoting premixed feed |
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Application publication date: 20180529 |