CN108310036A - The estrualization agent that breeding season sow uses - Google Patents
The estrualization agent that breeding season sow uses Download PDFInfo
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- CN108310036A CN108310036A CN201810091441.5A CN201810091441A CN108310036A CN 108310036 A CN108310036 A CN 108310036A CN 201810091441 A CN201810091441 A CN 201810091441A CN 108310036 A CN108310036 A CN 108310036A
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- sow
- siraitia grosvenorii
- breeding season
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- estrualization
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/13—Preparation or pretreatment of starting material involving cleaning, e.g. washing or peeling
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/37—Extraction at elevated pressure or temperature, e.g. pressurized solvent extraction [PSE], supercritical carbon dioxide extraction or subcritical water extraction
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- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
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- Mycology (AREA)
- Medicines Containing Plant Substances (AREA)
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Abstract
The invention discloses the estrualization agents that breeding season sow uses, and are prepared by the following preparation method：1) feedstock processing：By fresh prematurity Siraitia grosvenorii, the Siraitia grosvenorii fallen, the villus on removal Siraitia grosvenorii surface adds fresh stem of Siraitia grosvenori, the leaf of 1/5 1/4 weight；2) Subcritical Water Extraction：The raw material that upper step is obtained, is smashed, the deionized water of the weight such as addition, progress Subcritical Water Extraction, 120 150 DEG C of Extracting temperature, 5 8MPa of pressure, 10 15min of extraction time, and extraction terminates, and extract liquor is collected in pressure release；3) it filters：The extract liquor that upper step is obtained is filtered by 0.45 μm, is sealed, is obtained.
Description
Technical field
The invention belongs to the estrualization agents that pig cultural technique field more particularly to breeding season sow use.
Background technology
The breeding of sow, the target with inter-species kind are bred in due course with the sow of body condition with herd boar with meeting with health
To improve pregnancy rate, the daily management for sow of weaning should focus on heat stimulation.After wean, breast can be swollen because of galactosis
It bulges and, when the secretion of milk is with holding balance is reabsorbed, suckling process will taper off.After wean 2-3 days, breast is swollen
Swollen reduction, celluar tissue start to decompose, while FSH (follicular stimulating hormone) stimulates Oocyte Development at ovarian follicle, and folliculus ovarii is tough
Band will quickly increase and start to secrete estrogen, prepare to receive fertilized eggs for uterus, and stimulate performance symptom of estrus,
Estrogen can promote the secretion of LH (lutropin), LH follicular development can be made at ovum, and accelerate to ovulate.This stage is boar
The important stage of management, effective breeding just determine farrowing as a result, wean influences farrowing index to breeding interval, also influence
Litter size.The management of gestation and nursery phase has a major impact wean to the interval of breeding of sow.With pig cultural technique
Continuously improve, pig-breeding structure just towards scale, intensive, specialized aquaculture model is fast-developing.Wherein, litter size
It is the important indicator for weighing sow reproductive performance, improves sow the first-born litter size, help to improve the lifelong breeding achievement of sow.
Pig farm sow is when being bred at present, since the heat situation of wean sow is poor or breeding means are unreasonable
And other reasons so that first breeding or unsuccessful for the breeding again of Suprapubic arch sling, long-term nonpregnant sow proportion
Greatly, added cost is fed, there are larger economic losses, and additionally, due to that cannot breed in time, the farrowing rate on pig farm can be by very
Big to influence, economic benefit is difficult to improve, to be unfavorable for the development on pig farm.
It is presently used for before breeding in the daily ration of sow nurturing period, energy level and source can significantly affect the first feelings of sow
Phase starts, the quality of Oestrus rate and egg mother cell.It has been investigated that high-energy level remarkably promotes Insulin, IGF- in blood
The secretion of 1 and Leptin increases the secretion frequency of LH, therefore the Oestrus rate and ovulation rate to improve sow increase in daily ration
Add fat content that can improve triglyceride and total cholesterol concentration in blood, and E2 is promoted to secrete, is conducive to sow puberty
Start；And increase content of starch, as energy level improves, large follicle number increases, and IGF-1, E2 concentration increase in liquor folliculi, then
Be conducive to the maturation of egg mother cell.
Same reason, for the sow of breeding season, a kind of estrualization agent that can greatly transfer oestrus of sow stimulation of exploitation,
Or method of promoting the sexual maturity, it is successfully bred to primiparity and Suprapubic arch sling, improves the pregnancy rate of sow namely becoming pregnant to life for sow
Pig production has conclusive influence, the pregnancy rate for how further increasing sow significant.
Invention content
It is an object of the present invention to provide the estrualization agents that breeding season sow uses, by increasing the secretion of Gilt Uterus, adjusting body
Interior reproductive hormone secretion, adjusts the cyclostage of sow, promotees its heat.
The invention is realized by the following technical scheme：
The estrualization agent that breeding season sow uses, is prepared by the following preparation method：
1) feedstock processing：By fresh prematurity Siraitia grosvenorii, the Siraitia grosvenorii fallen, the villus on Siraitia grosvenorii surface is removed, then
Fresh stem of Siraitia grosvenori, the leaf of 1/5-1/4 weight is added；
2) Subcritical Water Extraction：The raw material that upper step is obtained, is smashed, and the deionized water of the weight such as addition carries out subcritical
Water extracts, 120-150 DEG C of Extracting temperature, pressure 5-8MPa, extraction time 10-15min, and extraction terminates, pressure release, collects extraction
Liquid；
3) it filters：The extract liquor that upper step is obtained is filtered by 0.45 μm, is sealed, is obtained.
The villus on the removal Siraitia grosvenorii surface described in step 1) of the present invention, preferably by way of polishing or wiping.
Smashing described in step 1), it is 0.5mm or less preferably to smash to grain size.
The estrualization agent that the breeding season sow that the present invention obtains uses, when in use, timing every morning warm water is to sow
Body surface and vaginal orifice are cleaned, and are dried after cleaning, input the breeding season sow of 30-40mL to Gilt Uterus using inseminating syringe daily
The estrualization agent used.
Compared with prior art, the advantage of the invention is that：
1, the estrualization agent that the breeding season sow obtained using the present invention is used makes first farrowing sow, wean by oestrus sow
Sow heat as early as possible, can effectively improve the Oestrus rate with broad sow.
2, Siraitia grosvenorii is the Special plant in Guilin, and there is a large amount of plantation on Guilin periphery.The fruit of Siraitia grosvenorii and and Ye Junhan
There are Siraitia grosvenorii triterpenoid saponin, also a large amount of fructose, more than ten kinds of essential amino acid, aliphatic acid, flavone compound, dimension life
Plain C, trace element etc. can lead to a large amount of shedding, not in the planting process of Siraitia grosvenorii because of weather reason, pest and disease damage etc.
Mellow fruit etc., usually this part fruit can fall as offal treatment.The present invention passes through the utilization to this part Siraitia grosvenorii, a side
Face increases the benefit of Siraitia grosvenorii farmer, and on the other hand using Siraitia grosvenorii as the feed addictive of pig raising, effect is fine.And
And the present invention compares by the Subcritical Water Extraction to Siraitia grosvenorii and heats water extraction or alcohol extracting, under subcritical state, with
The hydrogen bond of the raising of temperature, subcritical water is opened or weakens, and to make water is high to Low to extract, can thus pass through control
The temperature and pressure of subcritical water processed makes the polarity of water change in wide range, to realize effective components from natural materials
Continuous extraction from water soluble ingredient to liposoluble constituent, and can realize selective extraction, retaining Siraitia grosvenorii active ingredient
Meanwhile irritating fruit blueness taste that new fresh fructus momordicae is carried can be effectively removed, a certain proportion of fresh stem of Siraitia grosvenori of addition,
Leaf prevents smell from being had an impact to pig.
3, existing studies have shown that Siraitia grosvenorii too sweet tea, be easy the impairment of the spleen.Siraitia grosvenorii such as with the sun dry can on behalf of the tea,
But it cannot be for a long time for tea.If it is drying drink more than can get angry, cough due to wind-heat evil preferably drinks or matches other heat-clearing cooling materials less
It drinks, nocturnal emission, enuresis nocturna person avoid, and drink in a short time harmless, and long-term drinking can lead to the decline of gastrointestinal function, cause chain pathology
Reaction.These drawbacks of Siraitia grosvenorii, are drawbacks to human body, equally, if as feed or feed addictive, can also influence pig
Stomach, Long-term Feeding can bring the gastro-intestinal problems of sow.The prior art, the use to Siraitia grosvenorii are mostly with reference to other plant
Either Chinese medicine is used directly as feed or feed addictive, and the present invention is compared using immature Siraitia grosvenorii, shedding
Mellow fruit, only sweetener component therein is greatly reduced, but other nutritional ingredients still remain, and is directly to make
For the uterus of sow, this drawback of ripe Siraitia grosvenorii is just avoided, pig is can effectively prevent and gastro-intestinal problems occurs.
4, ripe Siraitia grosvenorii, can dense yellowish-brown villus and mixed raw black glandular scale, villus be animal and plant for it is warming,
The Functional tissue resist the enemy, without nutrition, villus is easy shelter evil people and countenance evil practices (bacterium, mould, birds droppings, frass, pesticide etc.), and posts for itself
Infested, microbial growth good carrier.The study found that the microorganism of the every gram of enrichment in fresh fructus momordicae surface layer is up to millions of,
It is very big to human health risk.The prior art also has the research using Siraitia grosvenorii as feed, but the prior art is usually to adopt
Use fresh mature Siraitia grosvenorii either it is drying after Siraitia grosvenorii used as raw material, the villus of Siraitia grosvenorii and it is untreated or
Person's processing is clean, and when the villus of Siraitia grosvenorii is with estrualization agent is machined into, the germ or microorganism that villus carries can not be complete
It is complete to kill, the uterus of sow can be seriously affected, and it is of the invention, in process engineering, the villus of Siraitia grosvenorii is specially removed, is effectively kept away
This problem is exempted from.
Specific implementation mode
By the following examples with comparative example to further detailed description of the invention.But these embodiments are not considered as
Limitation of the present invention.
Embodiment 1：
The estrualization agent that breeding season sow uses, is prepared by the following preparation method：
1) feedstock processing：By fresh prematurity Siraitia grosvenorii, the Siraitia grosvenorii fallen, the suede on polishing removal Siraitia grosvenorii surface
Hair, adds fresh stem of Siraitia grosvenori, the leaf of 1/5 weight；
2) Subcritical Water Extraction：The raw material that upper step is obtained is smashed to grain size as 0.5mm hereinafter, the weight such as addition is gone
Ionized water carries out Subcritical Water Extraction, 120-150 DEG C of Extracting temperature, pressure 5-8MPa, extraction time 10-15min, extraction knot
Extract liquor is collected in beam, pressure release；
3) it filters：The extract liquor that upper step is obtained is filtered by 0.45 μm, is sealed, is obtained.
Embodiment 2：
The estrualization agent that breeding season sow uses, is prepared by the following preparation method：
1) feedstock processing：By fresh prematurity Siraitia grosvenorii, the Siraitia grosvenorii fallen, the suede on erasing removal Siraitia grosvenorii surface
Hair, adds fresh stem of Siraitia grosvenori, the leaf of 1/4 weight；
2) Subcritical Water Extraction：The raw material that upper step is obtained is smashed to grain size as 0.5mm hereinafter, the weight such as addition is gone
Ionized water carries out Subcritical Water Extraction, 120-150 DEG C of Extracting temperature, pressure 5-8MPa, extraction time 10-15min, extraction knot
Extract liquor is collected in beam, pressure release；
3) it filters：The extract liquor that upper step is obtained is filtered by 0.45 μm, is sealed, is obtained.
Comparative example 1：
Using fresh mature Siraitia grosvenorii as raw material.Other are the same as embodiment 1.
Comparative example 2：
It heats water extraction and replaces Subcritical Water Extraction, other are the same as embodiment 1.
Control group：
Conventinal breeding.
Experimental example：
The estrualization agent that the breeding season sow of the present invention uses, feeding experiment, feed (weight are carried out on our company pig farm respectively
Percentage)：Corn 30%, dregs of beans 25%, fish meal 25%, wheat bran 13%, brown sugar 4%, vegetable oil 2%, multi-vitamins 1%.
Conclusion：The estrualization agent that breeding season sow using the present invention uses can effectively improve the Oestrus rate of sow before breeding,
It improves average number born alive and piglet is averaged Birth weight, meanwhile, it can effectively prevent pig and vaginitis occur.
The present invention has also been contrast experiment in early period for the Subcritical Water Extraction extraction of prematurity Siraitia grosvenorii, uses 130-
140 DEG C of temperature range, effect 120-150 DEG C of temperature range of ratio, still having gap, analysis is taken out because temperature range is wide
The substance come is more, more meets with the big feature of broad sow nutritional need.
Claims (4)
1. the estrualization agent that breeding season sow uses, which is characterized in that be prepared by the following preparation method：
1) feedstock processing：By fresh prematurity Siraitia grosvenorii, the Siraitia grosvenorii fallen, the villus on removal Siraitia grosvenorii surface adds
Fresh stem of Siraitia grosvenori, the leaf of weight；
2) Subcritical Water Extraction：The raw material that upper step is obtained, is smashed, and the deionized water of the weight such as addition carries out subcritical water extraction
It takes, 120-150 DEG C of Extracting temperature, pressure 5-8MPa, extraction time 10-15min, extraction terminates, pressure release, collects extract liquor；
3) it filters：The extract liquor that upper step is obtained is filtered by 0.45 μm, is sealed, is obtained.
2. the estrualization agent that breeding season sow according to claim 1 uses, it is characterised in that：Removal sieve described in step 1)
The villus on Chinese fruit surface, is by way of polishing or wiping.
3. the estrualization agent that breeding season sow according to claim 1 uses, it is characterised in that：Smashing described in step 1),
Be smash to grain size be 0.5mm or less.
4. the estrualization agent that breeding season sow according to claim 1 uses, it is characterised in that：When in use, every morning
Timing cleans sow body surface and vaginal orifice with warm water, is dried after cleaning, inputs 30- to Gilt Uterus using inseminating syringe daily
The estrualization agent that the breeding season sow of 40mL uses.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810091441.5A CN108310036A (en) | 2018-01-30 | 2018-01-30 | The estrualization agent that breeding season sow uses |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810091441.5A CN108310036A (en) | 2018-01-30 | 2018-01-30 | The estrualization agent that breeding season sow uses |
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| Publication Number | Publication Date |
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| CN108310036A true CN108310036A (en) | 2018-07-24 |
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| CN201810091441.5A Pending CN108310036A (en) | 2018-01-30 | 2018-01-30 | The estrualization agent that breeding season sow uses |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105475653A (en) * | 2015-12-30 | 2016-04-13 | 双胞胎（集团）股份有限公司 | Feed additive capable of controlling constipation of sows |
| CN105661069A (en) * | 2016-01-22 | 2016-06-15 | 广州暨南生物医药研究开发基地有限公司 | Feed additive for improving swine reproductive performance and preparation method thereof |
| CN106359268A (en) * | 2016-08-30 | 2017-02-01 | 界首市颖南万福家庭农场 | Method for cultivating sow in mating period |
| CN107087485A (en) * | 2017-04-25 | 2017-08-25 | 龙胜裕丰农业发展有限公司 | A kind of tomato non-pollution implantation methods |
| CN107098730A (en) * | 2017-04-25 | 2017-08-29 | 龙胜裕丰农业发展有限公司 | A kind of growing tomatoes spray nutritious liquor |
-
2018
- 2018-01-30 CN CN201810091441.5A patent/CN108310036A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105475653A (en) * | 2015-12-30 | 2016-04-13 | 双胞胎（集团）股份有限公司 | Feed additive capable of controlling constipation of sows |
| CN105661069A (en) * | 2016-01-22 | 2016-06-15 | 广州暨南生物医药研究开发基地有限公司 | Feed additive for improving swine reproductive performance and preparation method thereof |
| CN106359268A (en) * | 2016-08-30 | 2017-02-01 | 界首市颖南万福家庭农场 | Method for cultivating sow in mating period |
| CN107087485A (en) * | 2017-04-25 | 2017-08-25 | 龙胜裕丰农业发展有限公司 | A kind of tomato non-pollution implantation methods |
| CN107098730A (en) * | 2017-04-25 | 2017-08-29 | 龙胜裕丰农业发展有限公司 | A kind of growing tomatoes spray nutritious liquor |
Non-Patent Citations (1)
| Title |
|---|
| 梁剑平编: "《兽医中药学及实验技术》", 31 January 2012, 军事医学科学出版社 * |
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Application publication date: 20180724 |