CN107996846A - A kind of mixed feed additive for animals and preparation method and application - Google Patents
A kind of mixed feed additive for animals and preparation method and application Download PDFInfo
- Publication number
- CN107996846A CN107996846A CN201711240227.3A CN201711240227A CN107996846A CN 107996846 A CN107996846 A CN 107996846A CN 201711240227 A CN201711240227 A CN 201711240227A CN 107996846 A CN107996846 A CN 107996846A
- Authority
- CN
- China
- Prior art keywords
- feed additive
- animals
- mixed feed
- mixture
- mixed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/195—Antibiotics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/163—Sugars; Polysaccharides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/24—Compounds of alkaline earth metals, e.g. magnesium
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K40/00—Shaping or working-up of animal feeding-stuffs
- A23K40/10—Shaping or working-up of animal feeding-stuffs by agglomeration; by granulation, e.g. making powders
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
- A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Polymers & Plastics (AREA)
- Health & Medical Sciences (AREA)
- Food Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Animal Husbandry (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Emergency Medicine (AREA)
- Inorganic Chemistry (AREA)
- Fodder In General (AREA)
- Feed For Specific Animals (AREA)
Abstract
The invention discloses a kind of mixed feed additive for animals, it is characterised in that is made of the raw material of following percentage by weight：Chlortetracycline premix 50~80%, fumaric acid tiamulin 1~10%, maltodextrin 1~15%, microcrystalline cellulose 1~15%, calcium carbonate 1~30%.Mixed feed additive of the present invention, the blank of the mixed feed additive without animals for treating breathing problem is filled up, breach existing Chlortetracycline premix and the characteristics of fumaric acid tiamulin pre-mixing agent individually uses, fumaric acid tiamulin pre-mixing agent palatability is poor, dust is big, penetrating odor is strong, it can ensure poultry feed intake, dosage has been effectively ensured, the cure rate of disease for animals is improved, and reduces the waste of medicine.It is applicable to treatment poultry breathing problem and there is certain growth promoting function.
Description
Technical field
The invention belongs to field of medicine preparing technology, and in particular to a kind of novel veterinary mixed feed additive and its system
Preparation Method and application.
Background technology
Chlortetracycline premix, its effective medicinal ingredient are aureomycin, the main protein synthesis for suppressing sensitive microbial.Its
Has a broad antifungal spectrum, can press down gram positive bacteria, negative bacterium, conveyor screw, rickettsia, mycoplasma, Chlamydia, part protozoon etc.
System.
Fumaric acid tiamulin, is mainly used for preventing chronic respiratory disease, porcine mycoplasmal pneumonia, actinomyces property pleura
Pneumonia and treponema dysentery etc..Low dosage can promote to grow, and improve efficiency of feed utilization.Tiamulin is with aureomycin with 1：
3 compatibility mixed feedings, can treat pig bacterial enteritis, bacterial pneumonia, treponema swine dysentery, to Eaton agent pneumonia, bronchus
Pneumonia caused by sepsis bordetella bacilli and pasteurella multocida mixed infection is evident in efficacy.
At present, in the market fumaric acid tiamulin on sale and Chlortetracycline premix are single preparations of ephedrine, inconvenient for use；
Meanwhile fumaric acid when being compounded with aureomycin hydrochloride stability it is poor, easily cause aureomycin content (in terms of aureomycin hydrochloride) reduction
And generation chlorquatrimycin, cause toxicity to increase, therefore urgently develop a kind of efficient composite feed additive of novel stabilising
Kind.
The content of the invention
Present invention aims at a kind of mixed feed additive for animals of offer, while it is the present invention to provide its preparation method
Second goal of the invention, there is provided its application be the present invention the 3rd goal of the invention.
To achieve the above object, the present invention adopts the following technical scheme that：
A kind of mixed feed additive for animals, is made of the raw material of following percentage by weight：Chlortetracycline premix 50~
80%, fumaric acid tiamulin 1~10%, maltodextrin 1~15%, microcrystalline cellulose 1~15%, calcium carbonate 1~30%.
The preparation method of the mixed feed additive for animals, includes the following steps：
1) material prepares：Chlortetracycline premix is crushed, crosses 100 mesh sieves；
2) material mixes：Fumaric acid tiamulin is mixed with maltodextrin, microcrystalline cellulose, calcium carbonate, must be mixed
Thing A；Mixture A is mixed to get mixture B with the Chlortetracycline premix that crushed in advance；
3) post-process：To obtain the final product into mixture B plus after water mixing through granulation, whole grain, drying, sub-sieve.
In step 2), carry out being mixed to get mixture A using equivalent dilution method of progressively increasing.
In step 2), mixture B is mixed when mixing in three-dimensional mixer, and the time of mixing is 5~10min.
In step 3), the addition of water is mixture B weight 30~60%.
In step 3), granulation, the concrete operations of whole grain are：Add water mixing to be placed in granulator mixture B to pelletize, then
Granulation gained particle is put into centrifugation pelletizing machine, whole grain 10~60 seconds under 150~250r/min.
In step 3), the dry, concrete operations of sub-sieve are：The uniform particle of whole grain is put into fluidized bed airflow drying machine
In, 80~150 DEG C of inlet air temperature of control, 50~100 DEG C of leaving air temp, dry 30~50min；Dried pellet through sieves, sieve
The particle of 20~60 mesh is selected, is got product, excessive or little particle excessively is crushed as raw material for standby again.
Application of the mixed feed additive for animals in terms of as poultry treatment of respiratory diseases medicine.
Application of the mixed feed additive for animals in terms of as poultry growth promotion medicine.
Usage and dosage：If being used as poultry breathing problem, its additive amount is added in basal diet according to 2kg/t,
Feed within one day twice, free water；
If for improving poultry growth promotion, its additive amount is added in basal diet according to 0.5kg/t, feeds within one day
Twice, free water.
In mixed feed additive formulations of the present invention, aureomycin, fumaric acid tiamulin are medicinal ingredient, and crystallite is fine
Dimension element is used as disintegrant, and maltodextrin is used as filler as adhesive, calcium carbonate；Raw material in formula can directly be bought general
Logical commercial product.Compared with traditional folk prescription Chlortetracycline premix, fumaric acid tiamulin pre-mixing agent, product stability is good, controls
Therapeutic effect is more preferable, and reduce be stained with wall, dust, choke people phenomena such as generation, it is more convenient to use.
Compared with prior art, the beneficial effects of the present invention are：
1) compared to folk prescription Chlortetracycline premix, fumaric acid tiamulin pre-mixing agent, mixed feed addition of the present invention
Agent is more abundant by the performance of scientific matching drug effect for two kinds of medicines, easy to use；
2) mixed feed additive process is being prepared, the operation such as raw material is by crushing, mixing, granulation, drying can be notable
Improve the uniformity and stability of product；Wherein prepare 20~60 mesh particle premix can effectively avoid product use during
Be stained with wall, rise dirt, choke people the shortcomings of；
3) mixed feed additive of the present invention, has filled up the mixed feed additive without animals for treating breathing problem
Blank, breach existing Chlortetracycline premix and fumaric acid tiamulin pre-mixing agent individually use, fumaric acid it is safe
The characteristics of wonderful rhzomorph palatability is poor, dust is big, penetrating odor is strong, it is ensured that poultry feed intake, so as to be effectively ensured to medicament
Amount, improves the cure rate of disease for animals, and reduces the waste of medicine, and cost significantly reduces；
4) it is verified by experiments, mixed feed additive of the present invention is equal in terms for the treatment of poultry breathing problem and growth promotion
With good result.
Embodiment
Technical scheme is further discussed in detail with reference to embodiments, but protection scope of the present invention
It is not limited thereto.
Embodiment 1
A kind of mixed feed additive for animals, is made of the raw material of following percentage by weight：Chlortetracycline premix 75%
(15% aureomycin of active ingredient, in terms of aureomycin hydrochloride), fumaric acid tiamulin 5%, maltodextrin 5%, microcrystalline cellulose
Element 10%, calcium carbonate 5%.
The preparation method of above-mentioned mixed feed additive for animals, includes the following steps：
1) material prepares：Chlortetracycline premix 75% (15% aureomycin of active ingredient, in terms of aureomycin hydrochloride) is crushed,
Cross 100 mesh sieves；
2) material mixes：Dilution method is progressively increased by fumaric acid tiamulin and maltodextrin, microcrystalline cellulose, carbon with equivalent
Sour calcium mixing, obtains mixture A；Mixture A is put into three-dimensional mixer with the Chlortetracycline premix that crushed in advance
10min is mixed, obtains mixture B；
3) post-process：To obtain the final product into mixture B plus after water mixing through granulation, whole grain, drying, sub-sieve.
Specifically, the water of mixture B weight 45% is added into mixture B, is stirred evenly, adds in granulator and pelletizes；
Obtained particle is put into centrifugation pelletizing machine, rotating speed 200r/min, whole grain 60s；The uniform particle of whole grain is put into stream
Change in bed pneumatic drier, 120 DEG C of inlet air temperature, 60 DEG C of leaving air temp, dry 45min；Pellet through sieves after will be dry, screening 20
~mesh particle, both obtains finished product, and excessive or little particle excessively is crushed as raw material for standby again.
Embodiment 2
A kind of mixed feed additive for animals, is made of the raw material of following percentage by weight：Chlortetracycline premix 50%
(active ingredient aureomycin hydrochloride 10%), fumaric acid tiamulin 3.3%, maltodextrin 6.7%, microcrystalline cellulose 15%,
Calcium carbonate 25%.
The preparation method of above-mentioned mixed feed additive for animals, with reference to embodiment 1, difference is, in step 2)
Incorporation time is 5min；In step 3), the addition of water is mixture B weight 30%；Put into centrifugation pelletizing machine, in
Whole grain 30 seconds under 150r/min；80 DEG C of inlet air temperature, 50 DEG C of leaving air temp, dry 50min.
Embodiment 3
A kind of mixed feed additive for animals, is made of the raw material of following percentage by weight：Chlortetracycline premix 50%
(active ingredient aureomycin hydrochloride 10%), fumaric acid tiamulin 3.3%, maltodextrin 6.7%, microcrystalline cellulose 10%,
Calcium carbonate 30%.
The preparation method of above-mentioned mixed feed additive for animals, with reference to embodiment 1, difference is, in step 3),
The addition of water is mixture B weight 60%；Put into centrifugation pelletizing machine, whole grain 10 seconds under 250r/min；Inlet air temperature
150 DEG C, 100 DEG C of leaving air temp, dry 30min.
Embodiment 4
A kind of mixed feed additive for animals, is made of the raw material of following percentage by weight：Chlortetracycline premix 80%
(active ingredient aureomycin hydrochloride 10%), fumaric acid tiamulin 1%, maltodextrin 1%, microcrystalline cellulose 15%, carbonic acid
Calcium 3%.
Embodiment 5
A kind of mixed feed additive for animals, is made of the raw material of following percentage by weight：Chlortetracycline premix 70%
(active ingredient aureomycin hydrochloride 10%), fumaric acid tiamulin 10%, maltodextrin 15%, microcrystalline cellulose 1%, carbonic acid
Calcium 4%.
The effect observation of the mixed feed additive of the present invention treatment fattening porcine respiratory disease of application examples 1
Experimental animal：Confirmed 20 growing and fattening pigs with breathing problem.
Clinical criteria：Sick pig coughs and asthma, shows as having difficulty in breathing, sound of stridulating, when breathing is in dog shape appearance
Gesture, abdominal respiration, the visible projection of rib cage is exposed during breathing, and Respiration Rate increase, flows thick white nasal mucus, and with anorexia.
Experimental method：The piglet with diarrhoeal diseases will be diagnosed and be randomly divided into experimental group and control group, isolated rearing, experimental group
10, control group 10.The treatment method that experimental group growing and fattening pigs use is that the mixed type of the embodiment of the present invention 1 is added in daily ration
Feed addictive, additive amount are added according to 2kg/t, are fed within one day twice, free water；Control group growing and fattening pigs treatment method is：
Isodose Chlortetracycline premix (in terms of aureomycin hydrochloride) single preparations of ephedrine is added in daily ration and fumaric acid tiamulin is pre-
Mixture single preparations of ephedrine, spice feeding, free water.
Curative effect diagnostic criteria：(1) fully recover：Clinical symptoms are wholly absent；(2) effectively：Clinical symptom relief, but do not disappear completely
Lose；(3) it is invalid：For clinical symptoms without significant change, the state of an illness has no mitigation, or even deteriorates.
Experimental result is shown in Table 1：Experimental group treatment cure rate is 90%, higher than control group by 10.0%；Experimental group treatment always has
Efficiency is 100%, higher than control group by 10%.
Table 1 fattens the clinical treatment outcome of porcine respiratory disease experiment
It can be seen from the above that mixed feed additive of the present invention and traditional Chlortetracycline premix single preparations of ephedrine, fumaric acid
Tiamulin pre-mixing agent single preparations of ephedrine, which is used in mixed way, to be compared, and is breathed using mixed feed additive of the present invention in treatment growing and fattening pigs
In terms of tract disease, cure rate and total effective rate significantly improve.
The effect observation of the mixed feed additive of the present invention treatment chickens respiratory disease of application examples 2
Experimental animal：Confirmed 40 broiler chicken with breathing problem.
Clinical criteria：Sneeze, get rid of nose, cough, asthma, and with breathing rale, with progression of the disease, may occur in which
Shed tears, eyelid side or bilateral swelling, there is hemoptysis phenomenon when serious.Row's green, yellow-white or white loose stools, growth retardation.
Experimental method：The broiler chicken with breathing problem will be diagnosed and be randomly divided into experimental group and control group, isolated rearing is real
Test group 20, control group 20.The treatment method that experimental group broiler chicken uses is that the mixing of the embodiment of the present invention 1 is added in daily ration
Type feed addictive, additive amount are added according to 2kg/t, are fed within one day twice, free water；Control group broiler chicken treatment method is：
Isodose Chlortetracycline premix (in terms of aureomycin hydrochloride) single preparations of ephedrine is added in daily ration and fumaric acid tiamulin is pre-
Mixture single preparations of ephedrine, spice feeding, free water.
Curative effect diagnostic criteria：(1) fully recover：Clinical symptoms are wholly absent；(2) effectively：Clinical symptom relief, but do not disappear completely
Lose；(3) it is invalid：For clinical symptoms without significant change, the state of an illness has no mitigation, or even deteriorates.
Experimental result is shown in Table 2：Experimental group treatment cure rate is 95%, higher than control group by 15.0%；Experimental group treatment always has
Efficiency is 100%, higher than control group by 10%.
The clinical treatment outcome of 2 chickens respiratory disease of table experiment
It can be seen from the above that mixed feed additive of the present invention and traditional Chlortetracycline premix single preparations of ephedrine, fumaric acid
Tiamulin pre-mixing agent single preparations of ephedrine, which is used in mixed way, to be compared, using mixed feed additive of the present invention in treatment chickens respiratory
In terms of disease, cure rate and total effective rate significantly improve.
The somatotrophic effect observation of mixed feed additive of the present invention of application examples 3
Experimental animal：Confirmed 60 first 40 age in days piglets of the health without disease.
Experimental method：60 piglets are randomly divided into experimental group and control group, experimental group 30, control group 30.Experiment
Group adds the mixed feed additive of the embodiment of the present invention 1 in daily ration, and additive amount is added according to 0.5kg/t, feeds within one day
Twice, free water.Control group adds isodose Chlortetracycline premix (in terms of aureomycin hydrochloride) single preparations of ephedrine in daily ration
With the mix preparation of fumaric acid tiamulin pre-mixing agent single preparations of ephedrine, spice feeding, free water.
Effect assessment standard：(1) survival rate；(2) average weight；(3) feedstuff-meat ratio.
Experimental result is shown in Table 3：Experimental group control group survival rate is 100%；Experimental group average weight is higher than control group
1.5kg, feedstuff-meat ratio low 0.1.
The clinical effectiveness of 3 piglet growth promotion of table experiment
It can be seen from the above that mixed feed additive of the present invention and traditional Chlortetracycline premix single preparations of ephedrine, fumaric acid
Tiamulin pre-mixing agent single preparations of ephedrine, which is used in mixed way, to be compared, rectangular in piglet growth-promoting using mixed feed additive of the present invention
Face, cure rate and total effective rate significantly improve.
Claims (9)
1. a kind of mixed feed additive for animals, it is characterised in that be made of the raw material of following percentage by weight：Aureomycin is pre-
Mixture 50~80%, fumaric acid tiamulin 1~10%, maltodextrin 1~15%, microcrystalline cellulose 1~15%, calcium carbonate 1
~30%.
2. the preparation method of the mixed feed additive for animals described in claim 1, it is characterised in that include the following steps：
1）Material prepares：Chlortetracycline premix is crushed, crosses 100 mesh sieves；
2）Material mixes：Fumaric acid tiamulin is mixed with maltodextrin, microcrystalline cellulose, calcium carbonate, obtains mixture A；
Mixture A is mixed to get mixture B with the Chlortetracycline premix that crushed in advance；
3）Post processing：To obtain the final product into mixture B plus after water mixing through granulation, whole grain, drying, sub-sieve.
3. the preparation method of mixed feed additive for animals as claimed in claim 2, it is characterised in that step 2）In, adopt
Carry out being mixed to get mixture A with equivalent dilution method of progressively increasing.
4. the preparation method of mixed feed additive for animals as claimed in claim 2, it is characterised in that step 2）In, mix
Compound B is mixed when mixing in three-dimensional mixer, and the time of mixing is 5~10min.
5. the preparation method of mixed feed additive for animals as claimed in claim 2, it is characterised in that step 3）In, water
Addition be mixture B weight 30~60%.
6. the preparation method of mixed feed additive for animals as claimed in claim 5, it is characterised in that step 3）In, system
Grain, the concrete operations of whole grain are：Add water mixing to be placed in granulator mixture B to pelletize, then will granulation gained particle input
Into centrifugation pelletizing machine, whole grain 10~60 seconds under 150~250r/min.
7. the preparation method of mixed feed additive for animals as claimed in claim 2, it is characterised in that step 3）In, do
Dry, sub-sieve concrete operations are：The uniform particle of whole grain is put into fluidized bed airflow drying machine, control inlet air temperature 80~
150 DEG C, 50~100 DEG C of leaving air temp, dry 30~50min；Dried pellet through sieves, screen the particle of 20~60 mesh, i.e.,
Finished product is obtained, excessive or little particle excessively is crushed as raw material for standby again.
8. the answering in terms of as poultry treatment of respiratory diseases medicine of the mixed feed additive for animals described in claim 1
With.
9. application of the mixed feed additive for animals in terms of as poultry growth promotion medicine described in claim 1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711240227.3A CN107996846A (en) | 2017-11-30 | 2017-11-30 | A kind of mixed feed additive for animals and preparation method and application |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711240227.3A CN107996846A (en) | 2017-11-30 | 2017-11-30 | A kind of mixed feed additive for animals and preparation method and application |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107996846A true CN107996846A (en) | 2018-05-08 |
Family
ID=62055589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711240227.3A Pending CN107996846A (en) | 2017-11-30 | 2017-11-30 | A kind of mixed feed additive for animals and preparation method and application |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107996846A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111903701A (en) * | 2020-06-28 | 2020-11-10 | 武汉轻工大学 | Fly-killing premix for animals and preparation method and application thereof |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2909558A1 (en) * | 2006-12-12 | 2008-06-13 | Ceva Sante Animale Sa | Granulated medicated premixture, useful to treat infectious diseases, comprises orally administrable active ingredient, prepared by mixing the ingredient with a support/primary and secondary granulated excipient, wetting and stabilizing |
| CN101450067A (en) * | 2007-11-29 | 2009-06-10 | 天津瑞普生物技术集团有限公司 | Premixing agent for treating and preventing livestock and poultry respiratory disease |
| CN102319181A (en) * | 2011-09-08 | 2012-01-18 | 广东大华农动物保健品股份有限公司 | Enveloping process for micro-capsule animal medicament |
| CN104146949A (en) * | 2014-08-29 | 2014-11-19 | 宁夏泰瑞制药股份有限公司 | Premixing agent for tiamulin fumarate, and preparation method thereof |
| CN104490788A (en) * | 2014-11-26 | 2015-04-08 | 上海同仁药业有限公司 | Tiamulin fumarate particles and preparation method thereof |
| CN106265711A (en) * | 2016-08-25 | 2017-01-04 | 浦城正大生化有限公司 | Tylosin phosphonate pre-mixing agent formula and preparation technology |
| CN106822034A (en) * | 2016-12-02 | 2017-06-13 | 北京科百大科技有限责任公司 | The capsule core material or micro-capsule of drug containing are prepared as capsule core material with maize cob meal |
-
2017
- 2017-11-30 CN CN201711240227.3A patent/CN107996846A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2909558A1 (en) * | 2006-12-12 | 2008-06-13 | Ceva Sante Animale Sa | Granulated medicated premixture, useful to treat infectious diseases, comprises orally administrable active ingredient, prepared by mixing the ingredient with a support/primary and secondary granulated excipient, wetting and stabilizing |
| CN101450067A (en) * | 2007-11-29 | 2009-06-10 | 天津瑞普生物技术集团有限公司 | Premixing agent for treating and preventing livestock and poultry respiratory disease |
| CN102319181A (en) * | 2011-09-08 | 2012-01-18 | 广东大华农动物保健品股份有限公司 | Enveloping process for micro-capsule animal medicament |
| CN104146949A (en) * | 2014-08-29 | 2014-11-19 | 宁夏泰瑞制药股份有限公司 | Premixing agent for tiamulin fumarate, and preparation method thereof |
| CN104490788A (en) * | 2014-11-26 | 2015-04-08 | 上海同仁药业有限公司 | Tiamulin fumarate particles and preparation method thereof |
| CN106265711A (en) * | 2016-08-25 | 2017-01-04 | 浦城正大生化有限公司 | Tylosin phosphonate pre-mixing agent formula and preparation technology |
| CN106822034A (en) * | 2016-12-02 | 2017-06-13 | 北京科百大科技有限责任公司 | The capsule core material or micro-capsule of drug containing are prepared as capsule core material with maize cob meal |
Non-Patent Citations (1)
| Title |
|---|
| 张传斌等: "延胡索酸泰妙菌素颗粒的两种制粒工艺对比试验", 《兽药市场指南》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111903701A (en) * | 2020-06-28 | 2020-11-10 | 武汉轻工大学 | Fly-killing premix for animals and preparation method and application thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103504137B (en) | A kind of enteric bag is by type fodder acidulant and preparation method thereof | |
| CN102578387B (en) | A kind of slowly-releasing compound acidulant for animal and fowl fodder and preparation method thereof and feed | |
| CN101690717B (en) | Valnemulin for livestock and saline premix and preparation method thereof | |
| CN101843586A (en) | Water-soluble micro powder containing florfenicol and preparation method thereof | |
| CN108261410B (en) | Tylosin tartrate inclusion enteric-coated preparation and preparation method thereof | |
| CN104397349A (en) | Feeding intestinal tract sustained-release type compound acidifier and preparation method thereof | |
| CN107737106A (en) | Safe ten thousand rhzomorph sol particles of a kind of tartaric acid and preparation method thereof | |
| CN102511666A (en) | Oregano oil premix for livestock and poultry and preparation method | |
| CN103285374A (en) | Amoxicillin colistin sulphate granule and preparation method thereof | |
| CN101543601B (en) | Compound pharmaceutical composition for preventing and curing respiratory diseases in animals and preparation method thereof | |
| CN108967692A (en) | A kind of antibiotic-free piglet preweaning feed and preparation method | |
| CN101450067A (en) | Premixing agent for treating and preventing livestock and poultry respiratory disease | |
| CN109010320A (en) | A kind of double applications released in the agent of type Calcium polycarbophil particle and preparation method and livestock and poultry | |
| CN107996846A (en) | A kind of mixed feed additive for animals and preparation method and application | |
| CN105327334A (en) | Enteric coating pellets for treating piglet diarrhea and preparation method and application thereof | |
| CN102068412A (en) | Enteric targeted tilmicosin particles and preparation method thereof | |
| CN116998603A (en) | Efficient micromolecular organic acidulant and preparation method thereof | |
| CN112970942A (en) | Compound acidifier for slow-release feed and production method thereof | |
| CN101450061A (en) | Soluble powder for treating poultry bacterial infection | |
| CN104586875A (en) | Preparation method for compound tilmicosin enteric-coated granules | |
| CN104222484A (en) | Feed prepared through waste from xanthan gum production and preparation process of feed | |
| CN105146096B (en) | A kind of feed addictive preventing Porcine circovirus desease | |
| CN114886017A (en) | Fermented feed additive for enhancing immunity of livestock and poultry and preparation method thereof | |
| EP2123172A1 (en) | Method of preventing diseases in piglings in the weaning stage | |
| CN107996845A (en) | A kind of mixed feed additive for treating intestines problem and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180508 |