CN101450067A - Premixing agent for treating and preventing livestock and poultry respiratory disease - Google Patents

Premixing agent for treating and preventing livestock and poultry respiratory disease Download PDF

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Publication number
CN101450067A
CN101450067A CNA2007101505624A CN200710150562A CN101450067A CN 101450067 A CN101450067 A CN 101450067A CN A2007101505624 A CNA2007101505624 A CN A2007101505624A CN 200710150562 A CN200710150562 A CN 200710150562A CN 101450067 A CN101450067 A CN 101450067A
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China
Prior art keywords
respiratory disease
livestock
poultry
treating
adjuvant
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Pending
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CNA2007101505624A
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Chinese (zh)
Inventor
李旭东
鲍恩东
苏建东
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TIANJIN RINGPU BIOLOGICAL TECHNOLOGY GROUP Co Ltd
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TIANJIN RINGPU BIOLOGICAL TECHNOLOGY GROUP Co Ltd
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Priority to CNA2007101505624A priority Critical patent/CN101450067A/en
Publication of CN101450067A publication Critical patent/CN101450067A/en
Pending legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Feed For Specific Animals (AREA)

Abstract

The invention relates to a premixing agent for preventing and treating livestock and poultry respiratory disease, comprising tiamulin fumarate, chlortetracycline hydrochloride and auxiliary materials. The premixing agent is mainly use for preventing and treating swine enzzootic pneumonia and chook chronic respiratory disease, and can be suitable for treating swine enzzootic pneumonia, swine infections pleuropneumonia, hemolytic streptococcus, pig treponeme diarrhea and chook chronic respiratory disease, chook botryomycosis and so on. The secondary infection caused by bacteria can be simultaneously controlled when the chronic respiratory diseases of the livestock and poultry can be treated, the invention has certain growth-promoting action for the livestock and poultry in the growth phase, can effectively improve the utilization ratio of feed stuff, has high safety, can be suitable for popularization and application in the animal production.

Description

A kind of pre-mixing agent that is used to prevent and treat livestock and birds respiratory disease
Technical field
The invention belongs to field of veterinary, particularly relate to a kind of pre-mixing agent that is used to prevent and treat livestock and birds respiratory disease.
Background technology
Along with the expansion of intensive culture scale, the disease of each side such as the respiratory system disease of poultry, digestive system disease is more serious.Simultaneously because the abuse of antibiotics aspect livestock and poultry cultivation makes the problem of Resistant strain more and more serious.
With the fowl respiratory system disease is example, and the outburst of respiratory system disease has had a strong impact on fowl weightening finish and efficiency of feed utilization, and laying rate is reduced, the carcass quality degradation, even cause a considerable amount of death, influenced the economic benefit of foster fowl.The respiratory tract disease of fowl is more complicated in foster fowl produces, and the kind of disease is a lot, has virus to cause, has antibacterial and mycoplasma to cause, M ﹠ M does not wait.Clinical manifestation is shed tears, rhinorrhea, cough or sneeze, breathe, symptom such as dyspnea.
At present, the medicine that adopt in market mostly is antibiotics, is used for treatment and prevention respiratory tract disease, though little, the instant effect of these medicine dosage often can not treat that it is basic, because antibiotic abuse also makes bacterial strain produce drug resistance easily.Adopt the treatment by Chinese herbs livestock and birds respiratory disease to become one of effective treatment means.Yet at present the Chinese medicine preparation that uses clinically mostly is powder, exists problems such as administration inconvenience, consumption are big.
Summary of the invention
Based on above-mentioned situation, the object of the present invention is to provide a kind of novel pre-mixing agent prescription, be used to prevent and treat the pre-mixing agent of livestock and poultry respiratory tract infection.
The object of the present invention is achieved like this: represent to be respectively fumaric acid tiamulin 2%-3% with percentage by weight, chlortetracycline hydrochloride 7%-8%, adjuvant 89%-91%.
Described adjuvant comprises: anhydrous glucose, oral glucose, maize cob meal etc. are preferably anhydrous glucose.
In order to obtain better effect, preferred ingredient is: fumaric acid tiamulin 2.5%, chlortetracycline hydrochloride 7.5%, adjuvant 90%.
The present invention can adopt the general process of industry, equipment preparation.The following method preparation of preferred employing comprises step:
Earlier fumaric acid tiamulin, chlortetracycline hydrochloride are pulverized with used adjuvant, pulverized back mistake 60 mesh sieves; The adjuvant of getting fumaric acid tiamulin, chlortetracycline hydrochloride and equivalent with equivalent progressively increase the dilution method dilution, mixes, mistake 60 order fine screens three times obtain mixture; With mixture and remaining adjuvant mix homogeneously, mixture is crossed 80 order fine screens three times, promptly.
Fumaric acid tiamulin: claim safe wonderful spirit again, antimicrobial spectrum is similar to macrolide antibiotic, mainly acts on gram positive bacteria, and staphylococcus aureus, streptococcus, mycoplasma etc. are had stronger inhibitory action;
Chlortetracycline hydrochloride: antimicrobial spectrum is similar to tetramycin hydrochloride, but antibacterial action is strong than tetracycline, oxytetracycline.Can be used for additive during low dosage, chicken chronic respiratory tract disease, colibacillosis are had prevention and therapeutical effect preferably.
In order to verify clinical effectiveness of the present invention, get medicine of the present invention and do the clinical efficacy test on pig farm, Jinghai county.Get 20 of sick pigs that suffer from asthma, add pre-mixing agent of the present invention in feedstuff, add pre-mixing agent 400g of the present invention in every 1000kg feedstuff, logotype 5 days was a course of treatment.Through the treatment of a course of treatment, used trouble swine diseases feelings all take a turn for the better, and reach healing more than 85%, and effective percentage reaches more than 90%.
Beneficial effect: as can be seen by clinical trial, medicine of the present invention curative effect aspect the treatment livestock and birds respiratory disease is certain, the present invention fills a prescription and adopts fumaric acid tiamulin, two kinds of compatibility of drugss of chlortetracycline hydrochloride to use, can effectively prevent and treat asthma of various respiratory system diseases, particularly pig of poultry and the chronic respiratory tract disease of chicken.Control may also have certain growth promoting function to the poultry that are in trophophase because of bacterial secondary infection in the treatment livestock and birds respiratory disease, also can effectively improve the utilization rate of feedstuff, also has higher safety.Be suitable in herding is produced, applying.
The specific embodiment
Embodiment 1: earlier fumaric acid tiamulin 20g, chlortetracycline hydrochloride 70g and used adjuvant 910g are pulverized, pulverize back mistake 60 mesh sieves; The adjuvant of getting fumaric acid tiamulin, chlortetracycline hydrochloride and equivalent with equivalent progressively increase the dilution method dilution, mixes, mistake 60 order fine screens three times obtain mixture; With mixture and remaining adjuvant mix homogeneously, mixture is crossed 80 order fine screens three times, promptly get the about 1000g of pre-mixing agent, wherein contain fumaric acid tiamulin 20g, chlortetracycline hydrochloride 70g.
Be mainly used in control swine enzootic pneumonia and chronic respiratory disease.Be applicable to swine enzootic pneumonia, porcine contagious pleuropneumonia, Hemolytic streptococcus disease, pig treponema dysentery and chronic respiratory disease, chicken staphylococcosis etc.Usage and dosage: mixed feeding: add pre-mixing agent 410g of the present invention in pig, the every 1000kg feedstuff of chicken, logotype 3-5 days is a course of treatment.Forbid share with polyether antibiotics.
Embodiment 2: earlier fumaric acid tiamulin 25g, chlortetracycline hydrochloride 75g and used adjuvant 900g are pulverized, pulverize back mistake 60 mesh sieves; The adjuvant of getting fumaric acid tiamulin, chlortetracycline hydrochloride and equivalent with equivalent progressively increase the dilution method dilution, mixes, mistake 60 order fine screens three times obtain mixture; With mixture and remaining adjuvant mix homogeneously, mixture is crossed 80 order fine screens three times, promptly get the about 1000g of pre-mixing agent, wherein contain fumaric acid tiamulin 25g, chlortetracycline hydrochloride 75g.
Be mainly used in control swine enzootic pneumonia and chronic respiratory disease.Be applicable to swine enzootic pneumonia, porcine contagious pleuropneumonia, Hemolytic streptococcus disease, pig treponema dysentery and chronic respiratory disease, chicken staphylococcosis etc.Usage and dosage: mixed feeding: add pre-mixing agent 400g of the present invention in pig, the every 1000kg feedstuff of chicken, logotype 3-5 days is a course of treatment.Forbid share with polyether antibiotics.
Embodiment 3: earlier fumaric acid tiamulin 30g, chlortetracycline hydrochloride 80g and used adjuvant 890g are pulverized, pulverize back mistake 60 mesh sieves; The adjuvant of getting fumaric acid tiamulin, chlortetracycline hydrochloride and equivalent with equivalent progressively increase the dilution method dilution, mixes, mistake 60 order fine screens three times obtain mixture; With mixture and remaining adjuvant mix homogeneously, mixture is crossed 80 order fine screens three times, promptly get the about 1000g of pre-mixing agent, wherein contain fumaric acid tiamulin 30g, chlortetracycline hydrochloride 80g.
Be mainly used in control swine enzootic pneumonia and chronic respiratory disease.Be applicable to swine enzootic pneumonia, porcine contagious pleuropneumonia, Hemolytic streptococcus disease, pig treponema dysentery and chronic respiratory disease, chicken staphylococcosis etc.Usage and dosage: mixed feeding: add pre-mixing agent 390g of the present invention in pig, the every 1000kg feedstuff of chicken, logotype 3-5 days is a course of treatment.Forbid share with polyether antibiotics.

Claims (3)

1, a kind of pre-mixing agent that is used to prevent and treat livestock and birds respiratory disease is characterized in that the medicine that this pre-mixing agent comprises is: fumaric acid tiamulin, chlortetracycline hydrochloride and adjuvant.
2, a kind of pre-mixing agent that is used to prevent and treat livestock and birds respiratory disease according to claim 1, it is characterized in that: represent to be respectively fumaric acid tiamulin 2%-3% with percentage by weight, chlortetracycline hydrochloride 7%-8%, adjuvant 89%-91%, described adjuvant comprises: anhydrous glucose, oral glucose, maize cob meal etc. are preferably anhydrous glucose.
3, a kind of pre-mixing agent that is used to prevent and treat livestock and birds respiratory disease according to claim 1, it is characterized in that: preferred ingredient is: fumaric acid tiamulin 2.5%, chlortetracycline hydrochloride 7.5%, adjuvant 90%.
CNA2007101505624A 2007-11-29 2007-11-29 Premixing agent for treating and preventing livestock and poultry respiratory disease Pending CN101450067A (en)

Priority Applications (1)

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CNA2007101505624A CN101450067A (en) 2007-11-29 2007-11-29 Premixing agent for treating and preventing livestock and poultry respiratory disease

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Application Number Priority Date Filing Date Title
CNA2007101505624A CN101450067A (en) 2007-11-29 2007-11-29 Premixing agent for treating and preventing livestock and poultry respiratory disease

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101690717A (en) * 2009-09-30 2010-04-07 北京大北农动物保健科技有限责任公司 Valnemulin for livestock and saline premix and preparation method thereof
CN102600184A (en) * 2012-03-02 2012-07-25 山东胜利股份有限公司 Veterinary-use intestinal targeted antibacterial pellet and preparation method thereof
CN102716092A (en) * 2012-07-06 2012-10-10 浦城正大生化有限公司 Formula of aureomycin hydrochloride premix granule and granulating process
CN105902639A (en) * 2016-06-16 2016-08-31 福建傲农生物科技集团股份有限公司 Pharmaceutical preparation for prevention and treatment of chronic respiratory diseases of livestock and poultry and preparation method thereof
CN106491542A (en) * 2016-11-17 2017-03-15 四川伴农动保生物技术有限公司 Potentiation fumaric acid tiamulin pre-mixing agent and preparation method thereof
CN107996846A (en) * 2017-11-30 2018-05-08 驻马店华中正大有限公司 A kind of mixed feed additive for animals and preparation method and application
CN114796128A (en) * 2022-06-30 2022-07-29 山东国邦药业有限公司 Tiamulin fumarate premix and preparation method and application thereof

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101690717A (en) * 2009-09-30 2010-04-07 北京大北农动物保健科技有限责任公司 Valnemulin for livestock and saline premix and preparation method thereof
CN101690717B (en) * 2009-09-30 2013-03-06 北京大北农动物保健科技有限责任公司 Valnemulin for livestock and saline premix and preparation method thereof
CN102600184A (en) * 2012-03-02 2012-07-25 山东胜利股份有限公司 Veterinary-use intestinal targeted antibacterial pellet and preparation method thereof
CN102600184B (en) * 2012-03-02 2013-09-11 山东胜利股份有限公司 Veterinary-use intestinal targeted antibacterial pellet and preparation method thereof
CN102716092A (en) * 2012-07-06 2012-10-10 浦城正大生化有限公司 Formula of aureomycin hydrochloride premix granule and granulating process
CN102716092B (en) * 2012-07-06 2013-10-16 浦城正大生化有限公司 Formula of aureomycin hydrochloride premix granule and granulating process
CN105902639A (en) * 2016-06-16 2016-08-31 福建傲农生物科技集团股份有限公司 Pharmaceutical preparation for prevention and treatment of chronic respiratory diseases of livestock and poultry and preparation method thereof
CN106491542A (en) * 2016-11-17 2017-03-15 四川伴农动保生物技术有限公司 Potentiation fumaric acid tiamulin pre-mixing agent and preparation method thereof
CN107996846A (en) * 2017-11-30 2018-05-08 驻马店华中正大有限公司 A kind of mixed feed additive for animals and preparation method and application
CN114796128A (en) * 2022-06-30 2022-07-29 山东国邦药业有限公司 Tiamulin fumarate premix and preparation method and application thereof

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Open date: 20090610