CN102511666A - Oregano oil premix for livestock and poultry and preparation method - Google Patents
Oregano oil premix for livestock and poultry and preparation method Download PDFInfo
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- CN102511666A CN102511666A CN2011104592086A CN201110459208A CN102511666A CN 102511666 A CN102511666 A CN 102511666A CN 2011104592086 A CN2011104592086 A CN 2011104592086A CN 201110459208 A CN201110459208 A CN 201110459208A CN 102511666 A CN102511666 A CN 102511666A
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/70—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in livestock or poultry
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Abstract
The invention discloses an oregano oil premix for livestock and poultry and a preparation method. The oregano oil premix comprises the following components by weight percent: 2.5% to 10% of oregano oil, 2.5% to 10% of silicon dioxide powder and 80% to 95% of smectite powder. The novel premix product comprising oregano oil and smectite powder can be used for preventing and treating diarrhea caused by escherichia coli in pigs and chicken and salmonella, promoting growth of livestock and poultry, and improving the feed conversion rate, has an optimal compatible effect, does not bring no toxic or side effect, and is a green and safe premix product; and residues are avoided. The raw material powder of the product provided by the invention has the advantages of fineness, smoothness, large surface, good distribution and good using effect; and the finished product is small in particle size, has a good fluidity, and is easy to mix uniformly, so that good absorption, utilization and feeding effects can be achieved.
Description
Technical field
The present invention relates to a kind of veterinary drug pre-mixing agent, also relate to feed additive field, specifically, is that a kind of livestock and poultry are with origanum oil pre-mixing agent and preparation method.
Background technology
Origanum oil is the volatile oil that from the natural plants wild marjoram, extracts, at present can be artificial synthetic.This main component of essential oil is carvacrol and Thymol; The antibacterial activity of origanum oil is the same with other phenol derivatives, depends on the surface-active of its chemical constitution and fat-soluble, therefore very easily penetrates bacterial cell membrane; In endochylema, reduce the stability of albumen synzyme; Upset oxidizing process, destroy cell membrane, thereby suppress microbial growth.
These article have certain inhibitory action to gram-positive bacteria and negative bacterium, and streptococcus, staphylococcus, Escherichia coli, salmonella, Cray Bai Shi bacillus and enterococcus are responsive to these article.To dust Xi Shi Escherichia coli, salmonella typhimurium, have a liking for water hydrophila, Listeria, Staphylococcus aureus higher antibacterial activity all arranged, and these article are difficult for producing drug resistance.
Because origanum oil has the excellent antibiotic effect, have the effect that promotes growth of animals or poultry simultaneously, be widely used.
Mostly the common dosage forms of market supply is solution, pre-mixing agent, is mainly used in prevention and treatment pig, chicken, Escherichia coli, salmonellal diarrhea.Also be used to promote growth of animals or poultry, improve food conversion ratio (" People's Republic of China's veterinary drug allusion quotation veterinary drug guide for use " chemicals volume, 2005 version, the .92 of Chinese agriculture publishing house～93 pages).
Just the external origanum oil solution of the approval of import, origanum oil pre-mixing agent are used in the 9's 0 of last century in China; And its consumption increases year by year; Because the existing antibacterial action of this series products again can be as the growth regulator of livestock and poultry, and noresidue, nuisanceless, is accepted extensively by numerous raisers.
Origanum oil solution because consumption is little, is difficult to mix thoroughly in the adding feed, causes consumption to be difficult for controlling, and is directly for oral administration, because smell is dense often by ill livestock and poultry food refusal, causes very big inconvenience to use.The origanum oil pre-mixing agent has improved the convenience of using; Can mix in the feed equably and use; But its pre-mixing agent mostly adopts calcium carbonate or starch to add the direct mixed preparing of origanum oil; Particularly adopt organic excipient, to product in storage period quality all be difficult to be guaranteed, directly influence the product service efficiency.
A kind of origanum oil micro-capsule powder of method (ZL20041003379.3) preparation for preparing natural anti-bacteria agent for feeding origanum oil micro-capsule powder to the stability that improves its product and the effect of use, has played impetus.A kind of livestock and poultry that contain origanum oil have been developed a kind of new feed addictive with feed addictive and production method (ZL200510107322.7) thereof to the result of use that improves origanum oil, and can access to use effectively to origanum oil provides a kind of new process for producing.The application of these products undoubtedly to promoting the development of livestock and poultry breeding industry, has been played impetus.
Big, easy to use with regard to how making origanum oil good stability of products, decentralization better, the better and simple product of preparation technology of effect, the present invention is accomplished with origanum oil pre-mixing agent and preparation method by a kind of livestock and poultry.
Summary of the invention
The object of the present invention is to provide a kind of livestock and poultry to use the origanum oil pre-mixing agent.
Another object of the present invention also is to provide the preparation method of a kind of livestock and poultry with the origanum oil pre-mixing agent.
The object of the invention can be realized through following method; Origanum oil is adsorbed onto on the 1500 order fine silica equably obtains the origanum oil flour; Again with 1800 order montmorillonite powder mixings, directly with Drygranulatemachine adopt compacting, fragmentation, discharging, sieving obtains the origanum oil pre-mixing agent of 100 orders～120 order particle diameters.
A kind of livestock and poultry are used the origanum oil pre-mixing agent, are made up of origanum oil, silicon dioxide powder and montmorillonite powder, and their weight ratio is: origanum oil 2.5～10%, silicon dioxide powder 2.5～10%, montmorillonite powder 80～95%.
A kind of livestock and poultry of the present invention comprise the following steps: with the preparation method of origanum oil pre-mixing agent
Earlier origanum oil and silica 1 500 order powder are put that stirring makes origanum oil be adsorbed onto on the silicon dioxide powder fully in the mixer; Gradation adding montmorillonite 1800 order powder continue to stir again; Directly be pressed into the molecule powder with Drygranulatemachine; The molecule powder degree that is pressed into is 100～120 orders, promptly gets livestock and poultry with origanum oil pre-mixing agent product.
Used Drygranulatemachine adopts general Drygranulatemachine commonly used, process such as in comminutor, carry out compressing tablet, fragmentation, discharging, sieve.
Montmorillonite (montmorillonite) has another name called montmorillonite, and the montmorillonite powder that is used for feed is formed through purification processing by the dioctahedron montmorillonite, has very big surface area, can increase substantially adsorption capacity.Because montmorillonite has powerful suction-operated; Mould dose the product of selecting for use is taken off in conduct in feedstuff industry production, and through the test of forage science research institute of Zhejiang University, montmorillonite has strong suction-operated to mycotoxin; Absorption affinity (%) is as follows: aflatoxin, 100%; Zearalenone, 87%; Ochratoxin, 70%; Ergotoxin, 100%; Fumonism, 91%.
Montmorillonite loose (trade name: dioctahedral smectite, smecta) be widely used by clinical already as people's medication, pharmacology is introduced the adsorbable several diseases substance of dioctahedral smectite; Be fixed in the enteric cavity surface, then excrete, thereby avoid enterocyte to be damaged by pathogen with intestines peristalsis; Colitoxin, staphylotoxin and cholera toxin also there is fixation; Reduce the ataxia of enterocyte simultaneously, recover the normal rhythm of enterocinesia, safeguard the conveying and the absorption function of enteron aisle.In addition, dioctahedral smectite can also alleviate the mucosal tissue pathology due to the campylobacter jejuni, repairs the intercellular bridge that damages, and cell is closely connected, and prevents that pathogen from getting into blood circulation, and suppresses its breeding.The clinical acute and chronic diarrhea that is used for.
In aquaculture, antibiotic is a promoting animal growth and the product commonly used that improves feed conversion rate, in feed supplement with open and add antibiotic in the foodstuff; Both can control pathogenic microorganism propagation; Can quicken intestine immunity tolerance process again, thereby alleviate intestinal tract injury, the generation of prevention diarrhoea.But antibiotic prolonged application one is that pathogen is produced drug resistance, the 2nd, residually in animal products bring harm to health.
Montmorillonite powder is a kind of novel mineral medicament; Be used for treatment and diseases such as prevention fowl poultry kind diarrhoea, dysentery and have drug residue free, have no drug resistance, stable curative effect, advantage such as have no side effect; Escherichia coli, comma bacillus, campylobacter jejuni, staphylococcus aureus and rotavirus and cholate all there is suction-operated preferably; Bacterial poison is have fixation, can repair and improve the defense function of gastrointestinal mucosa virulence factor.It can not only absorbing pathogenic bacteria, also contains abundant vitamin, mineral matter, trace element.
In above-mentioned prescription, wherein silicon dioxide powder is a delicatessen food grade silicon dioxide powder; Montmorillonite powder is pharmaceutical grade or feed grade commercially available prod, and origanum oil is the commercially available prod.
Advantage of the present invention:
The new pre-mixing agent product that origanum oil and montmorillonite powder are formed; Be used to prevent and treat pig, chicken colibacillosis, salmonella diarrhea extremely; Promote growth of animals or poultry, improve food conversion ratio, can demonstrate the best compatibility effect that brings out the best in each other; And have no side effect, noresidue, be a kind of pre-mixing agent product of green safety.
The raw meal of product is fine and smooth, and surface area is big, and distributivity is good, and result of use is good, and the finished product particle diameter is little, good fluidity, and it is even to be easy to spice, has well to absorb and feeding effect.
Product of the present invention, production technology is simple, and product quality is steady, helps transportation, storage and the use of product.
The specific embodiment
Below in conjunction with embodiment the present invention is done further detailed description, but they are not to qualification of the present invention.
Embodiment 1
Present embodiment origanum oil premix preferred weight meter: origanum oil 2.5%, silicon dioxide powder 2.5%, cover shedding 95% and form.Its preparation method is; It is even in stirrer for mixing to take by weighing origanum oil and silicon dioxide powder (1500 order); Make origanum oil fully by silicon dioxide powder absorption, gradation adding montmorillonite powder (1800 order) stirs again, puts and directly is pressed into the molecule powder in the Drygranulatemachine; The granularity that makes the molecule powder that is pressed into is 100～120 orders, promptly gets livestock and poultry with origanum oil pre-mixing agent product.
Embodiment 2
Present embodiment origanum oil pre-mixing agent preferred weight meter: origanum oil 5%, silicon dioxide powder 5%, montmorillonite powder 90% are formed.
Its preparation method is; It is even in stirrer for mixing to take by weighing origanum oil and silicon dioxide powder (1500 order); Make origanum oil fully by silicon dioxide powder absorption, gradation adding montmorillonite powder (1800 order) stirs again, puts and directly is pressed into the molecule powder in the Drygranulatemachine; The granularity that makes the molecule powder that is pressed into is 100～120 orders, promptly gets livestock and poultry with origanum oil pre-mixing agent product.
Embodiment 3
Present embodiment origanum oil pre-mixing agent preferred weight meter: origanum oil 7.5%, silicon dioxide powder 7.5%, montmorillonite powder 85% are formed.
Its preparation method is; It is even in stirrer for mixing to take by weighing origanum oil and silicon dioxide powder (1500 order); Make origanum oil fully by silicon dioxide powder absorption, gradation adding montmorillonite powder (1800 order) stirs again, puts and directly is pressed into the molecule powder in the Drygranulatemachine; The granularity that makes the molecule powder that is pressed into is 100～120 orders, promptly gets livestock and poultry with origanum oil pre-mixing agent product.
Embodiment 4
Present embodiment origanum oil pre-mixing agent preferred weight meter: origanum oil 10%, silicon dioxide powder 10%, montmorillonite powder 80% are formed.
Its preparation method is; It is even in stirrer for mixing to take by weighing origanum oil and silicon dioxide powder (1500 order); Make origanum oil fully by silicon dioxide powder absorption, gradation adding montmorillonite powder (1800 order) stirs again, puts and directly is pressed into the molecule powder in the Drygranulatemachine; The granularity that makes the molecule powder that is pressed into is 100～120 orders, promptly gets livestock and poultry with origanum oil pre-mixing agent product.
Claims (2)
1. livestock and poultry are used the origanum oil pre-mixing agent, it is characterized in that, by the weight meter: origanum oil 2.5～10%, silicon dioxide powder 2.5～10%, montmorillonite powder 80～95% are formed.
2. a kind of livestock and poultry according to claim 1 are with the preparation method of origanum oil pre-mixing agent; It is characterized in that by the preparation of following method: earlier origanum oil and silica 1 500 order powder are put that stirring makes origanum oil absorb on the silicon dioxide powder fully in the mixer; Gradation adding montmorillonite 1800 order powder continue to stir again; Directly be pressed into the molecule powder with Drygranulatemachine, the molecule powder degree that is pressed into is 100～120 orders, and the livestock and poultry that get product are used the origanum oil pre-mixing agent.
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| CN2011104592086A CN102511666A (en) | 2011-12-29 | 2011-12-29 | Oregano oil premix for livestock and poultry and preparation method |
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| CN2011104592086A CN102511666A (en) | 2011-12-29 | 2011-12-29 | Oregano oil premix for livestock and poultry and preparation method |
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103583922A (en) * | 2013-11-25 | 2014-02-19 | 广州美瑞泰科生物工程技术有限公司 | Poultry used disease-resistant growth promotion green feed additive and preparing method thereof |
| CN103750038A (en) * | 2014-01-10 | 2014-04-30 | 华中农业大学 | Feed premix for resisting finishing pig transport stress and method for resisting finishing pig transport stress |
| CN105641623A (en) * | 2016-02-24 | 2016-06-08 | 禹州市合同泰药业有限公司 | Turmeric oil premix for livestock and poultry and preparation method of premix |
| CN105902638A (en) * | 2016-06-04 | 2016-08-31 | 郑堂勇 | Chinese herbal medicine compound for preventing and treating swine streptococcosis |
| CN109549021A (en) * | 2019-01-25 | 2019-04-02 | 刘锐 | A kind of bird feed additive and preparation method thereof and its application |
| CN110250100A (en) * | 2019-07-24 | 2019-09-20 | 河南爱诺生物科技有限公司 | It is a kind of using garlic P.E as the green natural plant compound and its method of main treatment egg avian escherichia coli and fallopian tubal |
| CN110279771A (en) * | 2019-06-21 | 2019-09-27 | 广西壮族自治区药用植物园 | A kind of Chinese medicine pre-mixing agent and preparation method thereof for preventing and treating bamboo rat diarrhea |
| CN111543548A (en) * | 2020-05-28 | 2020-08-18 | 河南创鑫生物科技有限公司 | Compound granular origanum oil premix and preparation method thereof |
| GB2585132A (en) * | 2019-04-08 | 2020-12-30 | Anpario Plc | Composition for reducing antimicrobial resistance |
| CN114376080A (en) * | 2020-10-20 | 2022-04-22 | 河北科星药业有限公司 | Cow feed additive containing amino acid, preparation method and application |
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Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103583922A (en) * | 2013-11-25 | 2014-02-19 | 广州美瑞泰科生物工程技术有限公司 | Poultry used disease-resistant growth promotion green feed additive and preparing method thereof |
| CN103583922B (en) * | 2013-11-25 | 2015-04-22 | 广州美瑞泰科生物工程技术有限公司 | Poultry used disease-resistant growth promotion green feed additive and preparing method thereof |
| CN103750038A (en) * | 2014-01-10 | 2014-04-30 | 华中农业大学 | Feed premix for resisting finishing pig transport stress and method for resisting finishing pig transport stress |
| CN103750038B (en) * | 2014-01-10 | 2015-07-22 | 华中农业大学 | Feed premix for resisting finishing pig transport stress and method for resisting finishing pig transport stress |
| CN105641623A (en) * | 2016-02-24 | 2016-06-08 | 禹州市合同泰药业有限公司 | Turmeric oil premix for livestock and poultry and preparation method of premix |
| CN105902638A (en) * | 2016-06-04 | 2016-08-31 | 郑堂勇 | Chinese herbal medicine compound for preventing and treating swine streptococcosis |
| CN109549021A (en) * | 2019-01-25 | 2019-04-02 | 刘锐 | A kind of bird feed additive and preparation method thereof and its application |
| GB2585132A (en) * | 2019-04-08 | 2020-12-30 | Anpario Plc | Composition for reducing antimicrobial resistance |
| GB2585132B (en) * | 2019-04-08 | 2021-12-22 | Anpario Plc | Composition for reducing antimicrobial resistance |
| CN110279771A (en) * | 2019-06-21 | 2019-09-27 | 广西壮族自治区药用植物园 | A kind of Chinese medicine pre-mixing agent and preparation method thereof for preventing and treating bamboo rat diarrhea |
| CN110250100A (en) * | 2019-07-24 | 2019-09-20 | 河南爱诺生物科技有限公司 | It is a kind of using garlic P.E as the green natural plant compound and its method of main treatment egg avian escherichia coli and fallopian tubal |
| CN111543548A (en) * | 2020-05-28 | 2020-08-18 | 河南创鑫生物科技有限公司 | Compound granular origanum oil premix and preparation method thereof |
| CN111543548B (en) * | 2020-05-28 | 2023-07-28 | 河南创鑫生物科技有限公司 | Compound granular oregano oil premix and preparation method thereof |
| CN114376080A (en) * | 2020-10-20 | 2022-04-22 | 河北科星药业有限公司 | Cow feed additive containing amino acid, preparation method and application |
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Application publication date: 20120627 |