CN107929229B

CN107929229B - Double-layer emulsion

Info

Publication number: CN107929229B
Application number: CN201711399009.4A
Authority: CN
Inventors: 蒲思凯; 彭熙春; 周雯; 关宝匀
Original assignee: Xianting Guangzhou Technology R & D Co ltd
Current assignee: Xianting (Guangzhou) technology R & D Co.,Ltd.
Priority date: 2017-12-19
Filing date: 2017-12-19
Publication date: 2021-07-09
Anticipated expiration: 2037-12-19
Also published as: CN107929229A

Abstract

The invention discloses a double-layer emulsion which comprises the following components in percentage by weight: 5-30% of an oil phase, 0.1-2.5% of an emulsifier, 0.3-10% of a humectant and 0.01-0.2% of a stabilizer; the emulsifier comprises inulin lauryl carbamate; the weight percentage of the inulin lauryl carbamate in the double-layer emulsion is 0.1-1%. The double layers of the facial mask are shaken up before use, so that a single-phase emulsion can be formed, and a layer of smooth and moisturizing grease protective film can be formed on the face after the facial mask is smeared, so that the percutaneous water loss of the skin is reduced, and the skin hydration degree is increased. The time for the product which is shaken up and mixed after standing to restore to a double-layer state is short, and the emulsion has the same effect as a single-phase emulsion and does not need to be added with a suspension stabilizer, so the spreadability of the emulsion is better, and the skin feel is more refreshing.

Description

Double-layer emulsion

Technical Field

The invention relates to an emulsion, in particular to a double-layer emulsion.

Background

With the improvement of the living standard of people and the enhancement of the skin care consciousness, the skin care problem is more and more concerned by both women and men. Among them, skin cleaning is used as the basis of skin care, and moisturizing and nursing are also indispensable after cleaning, so that the emulsion product also becomes an indispensable household daily article in daily life.

When the skin of a human body is in a healthy and normal state, a very thin sebum layer is secreted on the surface of the skin, so that the luster and the lubrication of the skin are kept. After skin is cleaned, the protection of the sebum layer of the skin becomes weak, and if moisture retention and moistening measures are not taken, the skin becomes dry and even itchy and dandruff can be removed because the moisture loss rate of the skin is increased.

Developers try to make a stable double-layer emulsion system, but the boundary of two phases is not obvious, and the lower water phase cannot present a clear and transparent state; after shaking up, the time for recovering to two phases is long, even the two-phase state can not be completely recovered; the phenomenon that the volume ratio of upper oil separation or two phases changes can occur after certain double-layer emulsions are placed for a long time.

Conventional emulsion products are single-phase products, and due to a thinner system, the problems of emulsification stability, such as layering, of high-content grease and some grease which is difficult to emulsify, such as non-polar grease or some vegetable grease, in a formula are particularly considered in the preparation process of the formula; and a proper amount of suspension stabilizer needs to be added into the formula to achieve a stable state, and the larger the addition amount of the suspension stabilizer is, the more viscous or heavy the skin feel of the formula is.

Chinese patent CN 102525923B discloses a method for preparing carotenoid emulsion and microcapsules, wherein electrostatic force of emulsifier molecules on an emulsion interface is utilized to interact in the formula, a two-step homogenization method is applied to prepare the carotenoid double-layer emulsion, and the carotenoid double-layer emulsion is further dried to prepare the microcapsules. The production process of the product in the patent needs high-temperature heating, and the product is produced by a separate two-step method, and the upper and lower layer states of the double-layer emulsion, whether the double-layer emulsion can be separated into a stable double-layer state again after shaking up or not and the stability of the two phases after being placed for a long time are not described in the whole text.

Disclosure of Invention

The invention aims to overcome the defects of the prior art and provide a double-layer emulsion.

In order to achieve the purpose, the invention adopts the technical scheme that: a double-layer emulsion comprises the following components in percentage by weight: 5-30% of an oil phase, 0.1-2.5% of an emulsifier, 0.3-10% of a humectant and 0.01-0.2% of a stabilizer; the emulsifier comprises inulin lauryl carbamate; the weight percentage of the inulin lauryl carbamate in the double-layer emulsion is 0.1-1%.

The invention uses inulin lauryl carbamate as emulsifier, the emulsifying structure schematic diagram of inulin lauryl carbamate and traditional emulsifier is shown in figure 1 and figure 2, because of the unique structure of emulsifier, the emulsifier contains strong hydrophilic inulin main chain and lipophilic lauryl long chain structure, and can be partially coated on the surface of oil drop, a steric hindrance barrier is formed on the interface of oil drop and water drop, the aggregation between the emulsion drops is reduced, and the stability of emulsion is improved. . Meanwhile, the particle size of the emulsion can be greatly reduced by strong homogenization in the process of emulsification, so that the skin feel of the emulsion is lighter and more comfortable, the stability is better, and the emulsifier has no thickening capability and is more favorable for layering of double-layer emulsion.

The double-layer emulsion is shaken up before use to form single-phase emulsion, and after the double-layer emulsion is smeared, a layer of smooth and moisturizing grease protective film can be formed on the face, so that the percutaneous water loss of the skin is reduced, and the skin hydration degree is increased. The time required for the product which is shaken up and mixed after standing to restore into a double-layer state is short, the single-phase emulsion has the same effect, the problem of layering phenomenon after the single-phase emulsion is placed for a long time does not need to be considered, and the dosage of the suspension stabilizer in the formula is also greatly reduced, so that the spreadability of the emulsion is better, and the skin feel is more refreshing. After the double-layer emulsion is stood for a long time, the proportion of the upper layer and the lower layer is relatively constant, and obvious increase or decrease can not occur. The consumer can personally participate in the mixing process of the product in the using process, and can observe the state that the single phase is separated into two phases after being mixed, so that the interestingness and the playability in the using process are improved.

Preferably, the weight ratio of inulin lauryl carbamate to oil phase is: inulin lauryl carbamate: oil phase 1: 50 to 150.

The inulin lauryl carbamate and the oil phase are in the range, so that the prepared double-layer emulsion has the appearance that the upper layer is emulsion and the lower layer is transparent liquid, and the two phases are layered.

More preferably, the weight ratio of inulin lauryl carbamate to oil phase is: inulin lauryl carbamate: oil phase 1: 80-120 parts.

The inulin lauryl carbamate and the oil phase have good stability in the double-layer emulsion prepared in the range. Still preferably, the weight ratio of inulin lauryl carbamate to oil phase is: inulin lauryl carbamate: the oil phase is 1: 90-110.

The inulin lauryl carbamate and the oil phase have the advantages of good stability and best skin feel.

Preferably, the oil phase is at least one of canola oil, moroion oil, sweet almond oil, olive oil, liquid paraffin, polydimethylsiloxane, cyclomethicone, isohexadecane, C12-15 alcohol benzoate, jojoba oil, isododecane, isononyl isononanoate, octyldodecanol, squalane, isoamyl laurate, C9-12 alkane, and coco-caprylate/caprate.

More preferably, the oil phase is a mixture of oil phase a and oil phase B; the oil phase A is at least one of common coltsfoot seed oil, Monoyi oil, sweet almond oil, olive oil, C12-15 alcohol benzoate, jojoba oil, squalane, isoamyl laurate and coconut oil alcohol-caprylate/caprate; the oil phase B is at least one of liquid paraffin, polydimethylsiloxane, cyclopolydimethylsiloxane, isohexadecane, isododecane and C9-12 alkane.

Wherein the oil phase A is polar oil; oil phase B is a nonpolar oil. When the polar oil and the nonpolar oil of the oil phase are matched by adopting the substances, the layering speed of the emulsion is high, and the clarity of the lower liquid layer is good.

Preferably, the weight ratio of the non-polar oil to the oil phase is: nonpolar oils: an oil phase is 2-10: 10.

more preferably, the weight ratio of the apolar oil to the oil phase is: nonpolar oils: and (3) oil phase is 5-9: 10.

still preferably, the weight ratio of the non-polar oil to the oil phase is: nonpolar oils: and (3) oil phase is 8-9: 10.

since polar greases affect the clarity of the underlying liquid layer, more polar content results in poorer clarity. When the nonpolar oil is prepared according to the proportion, the clarity of the lower liquid layer is optimal.

Preferably, the stabilizer is at least one of sodium hyaluronate, xanthan gum, sodium carbomer, hydroxypropyl methylcellulose, ammonium acryloyldimethyl taurate/VP copolymer, and hydroxyethyl cellulose.

More preferably, the stabilizer is sodium hyaluronate, hydroxypropyl methylcellulose, and hydroxyethyl cellulose.

Preferably, the stabilizer is sodium hyaluronate and hydroxyethyl cellulose; the weight percentage of the sodium hyaluronate in the double-layer emulsion is 0.05-0.1%, and the weight percentage of the hydroxyethyl cellulose in the double-layer emulsion is 0.08-0.1%.

More preferably, the stabilizer is sodium hyaluronate; the weight percentage of the sodium hyaluronate in the double-layer emulsion is 0.08-0.1%.

Preferably, the double-layer emulsion further comprises a two-phase regulator, a skin conditioner and a preservative, wherein the weight percentage of the two-phase regulator in the double-layer emulsion is 0-2%; the weight percentage content of the skin conditioner in the double-layer emulsion is 0-10%; the preservative accounts for 0.15-1% of the double-layer emulsion in percentage by weight.

Preferably, the two-phase regulator is sodium chloride; the weight percentage of the sodium chloride in the double-layer emulsion is 0.1-1.5%.

More preferably, the weight percentage of the sodium chloride in the double-layer emulsion is 0.5-1%.

Preferably, the skin conditioning agent comprises at least one of sodium PCA, manganese PCA, zinc PCA, magnesium PCA, papaya (CHAENOMELES SINENSIS) fruit extract, persimmon (DIOSPYROS KAKI) leaf extract, cinnamon (CINNAMOMUM CASSIA) bark extract, artemisia princeps (ARTEMISIA PRINCEPS) leaf extract, chamomile (CHRYSANTHELLUM INDICUM) extract, tea (CAMELLIA SINENSIS) leaf extract, lactobacillus/soymilk fermentation product filtrate, rice bran fermentation broth, and rose water.

The rice bran fermentation liquor mainly contains yeast/rice bran fermentation products.

Preferably, the humectant is at least one of glycerin, propylene glycol, butylene glycol, an amino acid humectant, methyl propylene glycol, and trehalose.

Preferably, the emulsifier further comprises at least one of sucrose laurate, polysorbate-60, polysorbate-20 and polyglycerol-10 laurate.

The sucrose laurate, polysorbate-60, polysorbate-20 and polyglycerol-10 laurate can be used as co-emulsifiers.

Preferably, the emulsifier is sucrose laurate and/or polysorbate-20.

More preferably, the emulsifier is sucrose laurate.

The sucrose laurate is a natural plant source component, does not contain PEG, has no risk substances and sensitization components, and can play a role in improving the appearance oil film layer of the double-layer emulsion in the emulsion.

Preferably, the weight ratio of the sucrose laurate, inulin lauryl carbamate and oil phase is: sucrose laurate: inulin lauryl carbamate: the oil phase is 0-16: 1: 100.

Preferably, the weight ratio of the sucrose laurate, inulin lauryl carbamate and oil phase is: sucrose laurate: inulin lauryl carbamate: the oil phase is 1-8: 1: 100.

Still more preferably, the weight ratio of the sucrose laurate, inulin lauryl carbamate and oil phase is: sucrose laurate: inulin lauryl carbamate: the oil phase was 1.6:1: 100. Because the viscosity of the double-layer emulsion is low, the sucrose laurate is mainly used for improving the appearance of a slight oil film on the upper layer of the double-layer emulsion prepared by only using the inulin laurate when the oil phase content is high, but the addition amount is too high, so that the layering speed and the skin feeling in use are influenced.

Preferably, the double-layer emulsion comprises the following components in percentage by weight: 0.1-1% of inulin lauryl carbamate, 0.3-3% of humectant, 5-30% of oil phase, 0.01-0.1% of stabilizer, 0.2-2% of sodium chloride and 200.1-2% of polysorbate-200.1; wherein the oil phase is a mixture of squalane, isohexadecane, C9-12 alkane and coco alcohol-caprylate/caprate; the weight ratio of squalane, isohexadecane, C9-12 alkane and cocol-caprylate/caprate is as follows: squalane, isohexadecane, C9-12 alkane, and coconut oil alcohol-caprylate/caprate ═ 1.5-8: 3-18: 0.9-4.5: 0.1-2.

Preferably, the weight ratio of inulin lauryl carbamate, squalane, isohexadecane, C9-12 alkane and coco alcohol-caprylate/caprate is: inulin lauryl carbamate: squalane: isohexadecane: c9-12 alkane: coco-caprylate/caprate ═ 1: 12: 72: 14.4: 1.6. preferably, the double-layer emulsion comprises the following components in percentage by weight: 0.1-0.15% of inulin lauryl carbamate, 0.3-3% of a humectant, 1.5-3% of squalane, 9-12% of isohexadecane, 1.8% of C9-12 alkane, 0.2% of coconut oil alcohol-caprylate/caprate, 0.08-0.1% of sodium hyaluronate, 0.8-1% of sodium chloride, 0.2% of sucrose laurate and 0.8% of a preservative; the preservative is p-hydroxyacetophenone and hexanediol.

In addition to the specific requirements of the components, other auxiliary components such as pH regulator, essence and the like can be added or used within the range of not damaging the effect of the invention, and the ordinary content can be selected by the skilled in the art according to the conventional standard.

Another object of the present invention is to provide a method for preparing the double-layer emulsion, which comprises the following steps:

1) adding the stabilizer into water, stirring uniformly, adding the humectant, the emulsifier, the two-phase regulator and the skin conditioner, and stirring uniformly to obtain a component A;

2) uniformly mixing the oil phase, adding the oil phase into the component A, and quickly homogenizing for 5-10 minutes to obtain a component B;

3) and adding a preservative into the component B, and uniformly stirring to obtain the double-layer emulsion.

The invention has the beneficial effects that: the invention provides a double-layer emulsion, which is shaken up before being used, can form a single-phase emulsion, and can form a layer of smooth and moisture-preserving grease protective film on the face after being smeared, thereby reducing the percutaneous water loss of the skin and increasing the skin hydration degree. The emulsion has the same effect as a single-phase emulsion, and does not need to be specially added with a suspension stabilizer, so the emulsion has better spreadability and more fresh skin feel. The time required for the product which is used and shaken up and mixed after standing to be restored to the double-layer state is short.

Drawings

FIG. 1 is the emulsified structure of inulin lauryl carbamate;

FIG. 2 is a conventional emulsifier emulsification structure;

wherein 1, the main chain of inulin; 2. a barrier to interfacial steric hindrance.

Detailed Description

To better illustrate the objects, aspects and advantages of the present invention, the present invention will be further described with reference to specific examples.

Example 1

In an embodiment of the double-layer emulsion of the present invention, the double-layer emulsion comprises the following components in percentage by weight:

10% of oil phase, 0.2% of emulsifier, 3.3% of humectant, 0.05% of stabilizer and 4.5% of skin conditioner; 1.0% of preservative, 0.03% of essence and the balance of water;

wherein the emulsifier is inulin lauryl carbamate and sucrose laurate; wherein the inulin lauryl carbamate accounts for 0.1 percent by weight of the double-layer emulsion, and the sucrose laurate accounts for 0.1 percent by weight of the double-layer emulsion; the oil phase is squalane, isohexadecane, C9-12 alkane and cocol-caprylate/caprate, wherein the weight percentage of squalane in the double-layer emulsion is 2%, the weight percentage of isohexadecane in the double-layer emulsion is 6%, the weight percentage of C9-12 alkane in the double-layer emulsion is 1.8%, and the weight percentage of cocol-caprylate/caprate in the double-layer emulsion is 0.2%;

the humectant is glycerin and amino acid humectant; wherein the weight percentage content of the glycerin in the double-layer emulsion is 0.3 percent, and the weight percentage content of the amino acid humectant in the double-layer emulsion is 3 percent;

the skin conditioning agent is a mixture of sodium PCA, manganese PCA, zinc PCA, magnesium PCA, papaya (CHAENOMELES SINENSIS) fruit extract, persimmon (DIOSPYROSS KAKI) leaf extract, cinnamon (CINNAMOMUM CASSIA) bark extract, Artemisia princeps (ARTEMISIA PRINCEPS) leaf extract, chamomile (CHRYSANTHELLUM INDICAUM) extract, tea (CAMELLIA SINENSIS) leaf extract, and lactobacillus/soymilk fermentation product filtrate, wherein the total weight percentage of the sodium PCA, manganese PCA, zinc PCA, and magnesium PCA in the double-layer emulsion is 2%; the stabilizer is hydroxyethyl cellulose; the preservative is p-hydroxyacetophenone and hexanediol.

The preparation method of the double-layer emulsion described in this example includes the following steps:

3) and adding a preservative and essence into the component B, and uniformly stirring to obtain the double-layer emulsion.

Example 2

30% of oil phase, 2.5% of emulsifier, 2% of two-phase regulator, 2% of skin conditioner, 0.1% of humectant, 0.05% of stabilizer, 0.8% of preservative, 0.03% of essence and the balance of water;

wherein the emulsifier is inulin lauryl carbamate, sucrose laurate and polysorbate-20; the weight percentage content of the inulin lauryl carbamate in the double-layer emulsion is 1 percent, the weight percentage content of the sucrose laurate in the double-layer emulsion is 1 percent, and the weight percentage content of the polysorbate-20 in the double-layer emulsion is 0.5 percent;

the oil phase is squalane, jojoba oil, isohexadecane, C9-12 alkane and cocol-caprylate/caprate, wherein the weight percentage of squalane in the double-layer emulsion is 2%, the weight percentage of jojoba oil in the double-layer emulsion is 3%, the weight percentage of isohexadecane in the double-layer emulsion is 15%, the weight percentage of C9-12 alkane in the double-layer emulsion is 9%, and the weight percentage of cocol-caprylate/caprate in the double-layer emulsion is 1%;

the humectant is glycerin;

the two-phase regulator is sodium chloride; the skin conditioner is rice bran fermentation liquor; the stabilizer is sodium hyaluronate; the preservative is p-hydroxyacetophenone and hexanediol.

The preparation of the double-layer emulsion described in this example was the same as in example 1.

Example 3

20% of oil phase, 0.6% of emulsifier, 3.6% of humectant, 1.0% of two-phase regulator, 0.08% of stabilizer, 0.15% of preservative, 0.03% of essence and the balance of water;

wherein the emulsifier is inulin lauryl carbamate and sucrose laurate; the weight percentage content of the inulin lauryl carbamate in the double-layer emulsion is 0.2 percent, and the weight percentage content of the sucrose laurate in the double-layer emulsion is 0.4 percent;

the oil phase is liquid paraffin, isohexadecane, cyclomethicone, C9-12 alkane and cocol-caprylate/caprate, wherein the weight percentage of the liquid paraffin in the double-layer emulsion is 3%, the weight percentage of the cyclomethicone in the double-layer emulsion is 5%, the weight percentage of the isohexadecane in the double-layer emulsion is 10%, the weight percentage of the C9-12 alkane in the double-layer emulsion is 1.8%, and the weight percentage of the cocol-caprylate/caprate in the double-layer emulsion is 0.2%;

the humectant is glycerin and amino acid humectant; wherein the weight percentage content of the glycerin in the double-layer emulsion is 0.6 percent, and the weight percentage content of the amino acid humectant in the double-layer emulsion is 3 percent;

the two-phase regulator is sodium chloride; the stabilizer is sodium hyaluronate; the preservative is bis (hydroxymethyl) imidazolidinyl urea and iodopropynyl alcohol butyl carbamate.

Example 4

5% of oil phase, 0.2% of emulsifier, 10% of humectant, 0.8% of two-phase regulator, 10% of skin conditioner, 0.1% of stabilizer, 0.8% of preservative, 0.03% of essence and the balance of water;

wherein the emulsifier is inulin lauryl carbamate and polysorbate-20; the weight percentage content of the inulin lauryl carbamate in the double-layer emulsion is 0.06 percent, and the weight percentage content of the polysorbate-20 in the double-layer emulsion is 0.14 percent;

the oil phase is the moenomy oil, isohexadecane, C9-12 alkane and cocol-caprylate/caprate, wherein the weight percentage of the moenomy oil in the double-layer emulsion is 1%, the weight percentage of the isohexadecane in the double-layer emulsion is 2%, the weight percentage of the C9-12 alkane in the double-layer emulsion is 1.8%, and the weight percentage of the cocol-caprylate/caprate in the double-layer emulsion is 0.2%;

the humectant is glycerol, methyl propylene glycol and trehalose; wherein the glycerin accounts for 2 percent by weight of the double-layer emulsion, the methyl propylene glycol accounts for 4 percent by weight of the double-layer emulsion, and the trehalose accounts for 4 percent by weight of the double-layer emulsion;

the two-phase regulator is sodium chloride; the skin conditioner is rose water; the stabilizer is sodium hyaluronate; the antiseptic is menthone and hexanediol.

Example 5

14.5% of oil phase, 0.65% of emulsifier, 2.6% of humectant, 0.01% of stabilizer, 0.8% of preservative, 0.1% of essence and the balance of water;

wherein the emulsifier is inulin lauryl carbamate and polysorbate-20; the weight percentage content of the inulin lauryl carbamate in the double-layer emulsion is 0.15 percent, and the weight percentage content of the polysorbate-20 in the double-layer emulsion is 0.5 percent;

the oil phase is squalane, isohexadecane, C9-12 alkane and cocol-caprylate/caprate, wherein the weight percentage of squalane in the double-layer emulsion is 1.5%, the weight percentage of isohexadecane in the double-layer emulsion is 9%, the weight percentage of C9-12 alkane in the double-layer emulsion is 3.6%, and the weight percentage of cocol-caprylate/caprate in the double-layer emulsion is 0.4%;

the humectant is glycerin; the stabilizer is a mixture of sodium hyaluronate and hydroxyethyl cellulose, the weight percentage content of the sodium hyaluronate in the double-layer emulsion is 0.07%, and the weight percentage content of the hydroxyethyl cellulose in the double-layer emulsion is 0.03%; the preservative is p-hydroxyacetophenone and hexanediol.

Example 6

12.5% of oil phase, 0.325% of emulsifier, 2.0% of humectant, 0.8% of two-phase regulator, 0.1% of stabilizer, 0.8% of preservative, 0.03% of essence and the balance of water;

wherein the emulsifier is inulin lauryl carbamate and polysorbate-20; the weight percentage content of the inulin lauryl carbamate in the double-layer emulsion is 0.125 percent, and the weight percentage content of the polysorbate-20 in the double-layer emulsion is 0.2 percent;

the oil phase is squalane, isohexadecane, C9-12 alkane and cocol-caprylate/caprate, wherein the weight percentage of squalane in the double-layer emulsion is 1.5%, the weight percentage of isohexadecane in the double-layer emulsion is 9%, the weight percentage of C9-12 alkane in the double-layer emulsion is 1.8%, and the weight percentage of cocol-caprylate/caprate in the double-layer emulsion is 0.2%;

the humectant is glycerin; the two-phase regulator is sodium chloride; the stabilizer is sodium hyaluronate; the preservative is p-hydroxyacetophenone and 1, 2-hexanediol.

Example 7

An embodiment of the double-layer emulsion of the present invention is different from embodiment 6 only in the addition amount of inulin lauryl carbamate, wherein in the embodiment, the weight percentage content of the inulin lauryl carbamate in the double-layer emulsion is 0.25%, the weight percentage content of the oil phase is 12.5%, that is, the weight ratio of the inulin lauryl carbamate to the oil phase is: inulin lauryl carbamate: oil phase 1: 50.

Example 8

An embodiment of the double-layer emulsion of the present invention is different from embodiment 6 only in the addition amount of inulin lauryl carbamate, in which the weight percentage content of the inulin lauryl carbamate in the double-layer emulsion is 0.156%, the weight percentage content of the oil phase is 12.5%, that is, the weight ratio of the inulin lauryl carbamate to the oil phase is: inulin lauryl carbamate: oil phase 1: 80.

Example 9

An embodiment of the double-layer emulsion of the present invention is different from embodiment 6 only in the addition amount of inulin lauryl carbamate, wherein the inulin lauryl carbamate accounts for 0.104% by weight of the double-layer emulsion, and the oil phase accounts for 12.5%; namely, the weight ratio of the inulin lauryl carbamate to the oil phase is as follows: inulin lauryl carbamate: oil phase 1: 120.

Example 10

An example of the double-layer emulsion of the present invention is different from example 6 only in the addition amounts of an oil phase and inulin lauryl carbamate, wherein the weight percentage of the inulin lauryl carbamate in the double-layer emulsion is 0.08%, and the oil phase is 12.5%; namely, the weight ratio of the inulin lauryl carbamate to the oil phase is as follows: inulin lauryl carbamate: oil phase 1: 150.

Example 11

The present invention is an example of a double-layer emulsion, which is different from example 6 only in the amount of sodium chloride, and does not contain sodium chloride.

Example 12

An embodiment of the double-layer emulsion of the present invention is different from embodiment 6 only in the addition amount of sodium chloride, and in this embodiment, the weight percentage of the sodium chloride in the double-layer emulsion is 0.5%.

Example 13

An embodiment of the double-layer emulsion of the present invention is different from embodiment 6 only in the addition amount of sodium chloride, and in this embodiment, the weight percentage of the sodium chloride in the double-layer emulsion is 1%.

Example 14

An embodiment of the double-layer emulsion of the present invention is different from embodiment 6 only in the addition amount of sodium chloride, and in this embodiment, the weight percentage of the sodium chloride in the double-layer emulsion is 1.5%.

Example 15

An embodiment of the double-layer emulsion of the present invention is different from embodiment 6 only in the addition amount of sodium chloride, and in this embodiment, the weight percentage of the sodium chloride in the double-layer emulsion is 2%.

Example 16

An example of the double-layer emulsion of the present invention is different from example 6 only in the amount of sucrose laurate, and the present example does not contain sucrose laurate.

Example 17

An embodiment of the double-layer emulsion of the present invention is different from embodiment 6 only in the addition amount of sucrose laurate, and in this embodiment, the sucrose laurate is 0.5% by weight in the double-layer emulsion.

Example 18

An embodiment of the double-layer emulsion of the present invention is different from embodiment 6 only in the addition amount of sucrose laurate, and in this embodiment, the sucrose laurate is 1% by weight in the double-layer emulsion.

Example 19

An embodiment of the double-layer emulsion of the present invention is different from embodiment 6 only in the addition amount of sucrose laurate, and in this embodiment, the sucrose laurate is 2% by weight in the double-layer emulsion.

Example 20

An embodiment of the double-layer emulsion of the present invention is different from embodiment 6 only in that the stabilizer is different, in this embodiment, the stabilizer is sodium hyaluronate and xanthan gum, and the weight percentage content of the sodium hyaluronate in the double-layer emulsion is 0.05%; the weight percentage of the xanthan gum in the double-layer emulsion is 0.05%.

Example 21

An embodiment of the double-layer emulsion of the present invention is different from embodiment 6 only in that the stabilizer is sodium hyaluronate, xanthan gum and carbomer sodium, in which the sodium hyaluronate is 0.05% by weight in the double-layer emulsion, the xanthan gum is 0.03% by weight in the double-layer emulsion, and the carbomer sodium is 0.02% by weight in the double-layer emulsion. The preparation of the double-layer emulsion described in this example was the same as in example 1.

Example 22

An embodiment of the double-layer emulsion of the present invention is different from embodiment 6 only in the difference of the stabilizer, in which the stabilizer is sodium hyaluronate and hydroxyethyl cellulose, the weight percentage of the sodium hyaluronate in the double-layer emulsion is 0.03%, and the weight percentage of the hydroxyethyl cellulose in the double-layer emulsion is 0.07%.

Comparative example

The emulsion of the double-layer emulsion is a single-layer emulsion, and the difference between the emulsion of the double-layer emulsion and the emulsion of the embodiment 6 is that the stabilizer is different, in the comparative example, the stabilizer is carbomer sodium and xanthan gum, the weight percentage content of the xanthan gum in the double-layer emulsion is 0.1%, the weight percentage content of the carbomer sodium in the double-layer emulsion is 0.2%, and the weight percentage content of the sodium chloride of the two-phase regulator is 0.05%.

Example 23

The double-layer emulsions described in examples 1-22 were subjected to sensory evaluation, stability testing, pH testing, and delamination rate testing.

1. Appearance: examples 1 to 22 the double-layer emulsion had an emulsion layer as the upper layer and a clear transparent layer as the lower layer.

2. Stability test: 5 ℃, 10 ℃, normal temperature, 48 ℃ and ultraviolet light for 3 months, wherein the phenomenon of chromatography oil appears after the heat resistance of the example 10 is kept for 48 hours, and other examples have no obvious change.

3. And (3) pH test: the pH value of the double-layer emulsion of the embodiment 1 to 22 is 6.0 to 6.8.

4. And (3) testing the layering speed:

the double-layer emulsions described in examples 1 to 22 were respectively filled into a 100ml graduated flask, the two phases were completely mixed by the same stirring speed and stirring time, and then the time required for re-layering was observed by standing, and the setting of observation time was tested: the first half hour is an observation period every 5 minutes, the observation period is set after standing for half an hour to 4 hours, a test observation period is set every 10 minutes, and a test observation period is set every 4 hours to 12 hours; every 4 hours for 12 hours to 48 hours is a test observation period; after 48 hours, every 24 hours is a test observation period. Retention of test data: the last bit is an integer multiple of 5. The test results are shown in Table 1.

TABLE 1 results of the delamination Rate test

As can be seen from Table 1, the emulsions described in examples 1 and 3-17 showed delamination within 5 minutes; the initial layering time of example 2 and examples 18-22 was longer; in examples 1 and 3 to 17, the time required for complete delamination varied depending on the content of the components or the ratio of the components to each other. The emulsion of example 10 and example 16 had a small oil film layer on the surface.

In table 1, the influence of the content of different oil phases in the formula on the layering speed of the formula is studied in examples 1 to 6, and it can be seen from the test results in table 1 that the proportion of the upper emulsion layer is correspondingly increased along with the increase of the proportion of the content of the oil phases in the formula.

Skin feel evaluation was performed for examples 1 to 6:

1) the test population: 14 women, between 20 and 35 years of age.

2) Test samples: the two-layer emulsions of examples 1-6.

3) The specific test method comprises the following steps: marking out six test areas of 2.5cm x 2.5cm on the inner sides of the left and right arms, uniformly smearing the same proper amount of emulsion in the test areas of the arms, and gently massaging until the emulsion is absorbed.

And (3) testing results: best evaluation of skin feel: example 1 was 3, example 2 was 0 (example 2 was considered too greasy), example 3 was 1, example 4 was 1, example 5 was 2, and example 6 was 7, thus it can be seen that example 6 had the best comfort.

In table 1, examples 6 to 10 study the ratio of inulin lauryl carbamate to oil phase, and it can be seen from the comparison of examples 6 to 10 that the ratio of inulin lauryl carbamate to oil phase is decreased, the speed of emulsion stratification is faster, and when the ratio is decreased or increased to a certain value, the ratio of the emulsion layer is correspondingly decreased and the emulsification effect of the system is affected.

Skin feel evaluation was performed for examples 6 to 10:

1) the test population: 14 women and 2 men, the age is between 20 and 35 years.

2) Test samples: examples 6 to 10 are the double-layer emulsions.

3) The specific test method comprises the following steps: marking five test areas of 2.5cm x 2.5cm on the inner sides of the left and right arms, uniformly smearing the same proper amount of emulsion in the test areas of the arms, and gently massaging until the emulsion is absorbed.

And (3) testing results: best evaluation of skin feel: example 6 was 12, example 7 was 0, example 8 was 0, example 9 was 3, example 10 was 1, and it can be seen that the weight ratio of inulin lauryl carbamate to oil phase was 1: the effect is optimal at 100 deg.C.

In Table 1, it can be seen from the comparative tests of examples 6 and 11 to 15 that the time required for complete delamination was shorter as the sodium chloride content in the system increased.

Skin feel evaluation was performed for example 6 and examples 11 to 15:

1) the test population: 14 women and 2 men, the age is between 20 and 35 years.

2) Test samples: the two-layer emulsion of examples 6 and 11 to 15.

And (3) testing results: best evaluation of skin feel: the skin feel was considered to be close to that of examples 6 and 11 to 15 and the skin feel was best for 9 persons, the skin feel was considered to be best for example 6 for 6 persons, and the skin feel was considered to be best for example 12 for 1 person, and slight tingling was considered to be felt in example 14 and example 15 for 1 person.

From the above results, it was found that the optimum amount of sodium chloride added to the double emulsion was 0.8%.

The best layering speed was evaluated for example 6 and examples 11 to 15:

the test method comprises the following steps: questionnaires were conducted on 15 persons who used a general base cosmetic and 10 persons who performed the production in the cosmetics shop, wherein the optimal layering time was 20 persons in example 6, the optimal layering speed was 3 persons in examples 12 and 13, respectively, and the optimal layering speed was 2 persons in example 14.

The results of the above tests were combined to show that the combined effect of example 6 was the best, followed by example 12 and example 13.

In Table 1, it can be seen from the comparison of examples 6 and 16 to 19 that the time for complete separation is longer as the amount of sucrose laurate is increased.

Skin feel evaluation was performed for example 6 and examples 16 to 19:

1) the test population: 14 women, between 20 and 35 years of age.

2) Test samples: the two-layer emulsion of example 6 and examples 16 to 19.

3) The specific test method comprises the following steps: marking four test areas of 2.5cm x 2.5cm on the inner sides of the left and right arms, uniformly smearing the same proper amount of emulsion in the test areas of the arms, and gently massaging until the emulsion is absorbed.

And (3) testing results: example 6 was considered to have 8 people with the most comfortable skin feel, example 16 was considered to have 6 people with the most comfortable skin feel, examples 17, 18 and 19 were considered to have 0 people with the most comfortable skin feel, of which 3 people considered example 18 to have a sticky skin feel and 8 people considered example 19 to have a sticky skin feel.

In example 16, which contained no sucrose laurate, the upper layer of the double emulsion had a slight oil film layer.

The above results were combined and analyzed, and the weight ratio of the amount of co-emulsifier added to inulin lauryl carbamate and the oil phase in the examples was 1.6:1: the optimum is 100.

Skin feel evaluation was performed on example 6 and examples 20 to 22:

1) the test population: 14 women, between 20 and 35 years of age.

2) Test samples: the two-layer emulsion of example 6 and examples 20 to 22.

And (3) testing results: example 6 is considered to have smooth and refreshing skin feeling and excellent moisture retention for 12 persons, and then example 21 for 2 persons. Of these, 9 considered the skin feel of example 20 to be relatively sticky, 4 considered the skin feel of example 22 to be slightly sticky when semi-dried, and 1 considered the slightly sticky feel of example 6 when semi-dried.

By combining the comparative analysis, the influence of different stabilizers on the layering time is large, wherein sodium hyaluronate is used alone, the thorough layering time is optimal when the addition amount is 0.1%, and the stabilizers with the suspending capacity such as carbomer and xanthan gum can obviously slow down the layering speed of the double-layer emulsion and increase the sticky feeling of the product when the product is applied.

5. The use effect evaluation was performed for example 6:

1) the test population: 14 women, between 20 and 35 years of age.

2) Test samples: double layer emulsion as described in example 6, single layer emulsion as described in comparative example, commercially available single layer emulsion of a certain brand.

3) The specific test method comprises the following steps: marking three test areas of 2.5cm by 2.5cm on the inner side of the arm, uniformly smearing the same proper amount of emulsion in the test area of the arm, and gently massaging until the emulsion is absorbed.

4) The evaluation results are shown in Table 2.

Table 2 evaluation results of usage effects

As can be seen from the results in Table 2, the two-layer emulsion of the present invention has a superior combination of effects to the single-layer emulsion and the commercially available emulsion.

Finally, it should be noted that the above embodiments are only used for illustrating the technical solutions of the present invention and not for limiting the protection scope of the present invention, and although the present invention is described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions can be made on the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention.

Claims

1. The double-layer emulsion is characterized by comprising the following components in percentage by weight: 5-20% of an oil phase, 0.1-2.5% of an emulsifier, 0.3-10% of a humectant, 0.08-0.1% of a stabilizer and 0.1-1.5% of a two-phase regulator; the emulsifier is a mixture of inulin lauryl carbamate and sucrose laurate or a mixture of inulin lauryl carbamate and polysorbate-20; the weight percentage content of the inulin lauryl carbamate in the double-layer emulsion is 0.1-1%; the weight ratio of the sucrose laurate to the inulin lauryl carbamate to the oil phase is as follows: sucrose laurate: inulin lauryl carbamate: oil phase 1-2:1: 100; the weight ratio of the polysorbate-20 to the inulin lauryl carbamate to the oil phase is as follows: polysorbate-20: inulin lauryl carbamate: oil phase 1.6:1: 100; the stabilizer is sodium hyaluronate; the two-phase regulator is sodium chloride.

2. The double emulsion of claim 1, wherein the oil phase is at least one of canola oil, moenomycin oil, sweet almond oil, olive oil, liquid paraffin, dimethicone, cyclomethicone, isohexadecane, C12-15 alcohol benzoate, jojoba oil, isododecane, isononyl isononanoate, octyldodecanol, squalane, isoamyl laurate, C9-12 alkane, and coco alcohol-caprylate/caprate.

3. The double emulsion of claim 2, wherein the oil phase is a mixture of oil phase a and oil phase B; the oil phase A is at least one of common coltsfoot seed oil, Monoyi oil, sweet almond oil, olive oil, C12-15 alcohol benzoate, jojoba oil, squalane, isoamyl laurate and coconut oil alcohol-caprylate/caprate; the oil phase B is at least one of liquid paraffin, polydimethylsiloxane, cyclopolydimethylsiloxane, isohexadecane, isododecane and C9-12 alkane.

4. The double-layer emulsion of claim 1, further comprising a skin conditioning agent and a preservative; the weight percentage content of the skin conditioner in the double-layer emulsion is 0-10%; the preservative accounts for 0.15-1% of the double-layer emulsion in percentage by weight.

5. The double-layer emulsion of claim 1, wherein the sodium chloride is present in the double-layer emulsion in an amount of 0.5 to 1.0% by weight.

6. The double-layer emulsion according to claim 1, wherein the double-layer emulsion comprises the following components in percentage by weight: 0.1-1% of inulin lauryl carbamate, 0.3-3% of humectant, 5-20% of oil phase, 0.01-0.1% of stabilizer, 0.2-2% of sodium chloride and 200.14-2% of polysorbate-200.14; wherein the oil phase is a mixture of squalane, isohexadecane, C9-12 alkane and coco alcohol-caprylate/caprate; the weight ratio of squalane, isohexadecane, C9-12 alkane and cocol-caprylate/caprate is as follows: squalane, isohexadecane, C9-12 alkane, and coconut oil alcohol-caprylate/caprate ═ 1.5-8: 3-18: 0.9-4.5: 0.1-0.5.

7. The double-layer emulsion of claim 6, wherein the weight ratio of inulin lauryl carbamate, squalane, isohexadecane, C9-12 alkane, and cocol-caprylate/caprate is: inulin lauryl carbamate: squalane: isohexadecane: c9-12 alkane: coco-caprylate/caprate ═ 1: 12: 72: 14.4: 1.6.