CN109106622B - Cleansing milk with moisturizing and repairing functions and preparation method thereof - Google Patents

Cleansing milk with moisturizing and repairing functions and preparation method thereof Download PDF

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CN109106622B
CN109106622B CN201811305283.5A CN201811305283A CN109106622B CN 109106622 B CN109106622 B CN 109106622B CN 201811305283 A CN201811305283 A CN 201811305283A CN 109106622 B CN109106622 B CN 109106622B
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skin
polyquaternium
peg
alcohol
moisturizing
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CN109106622A (en
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于寒
王丽辉
林锦雄
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Guangzhou Aibei Biological Technology Co Ltd
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Guangzhou Aibei Biological Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • A61K8/375Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/39Derivatives containing from 2 to 10 oxyalkylene groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/14Preparations for removing make-up
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/007Preparations for dry skin

Abstract

The invention discloses a moisturizing repair makeup removing lotion and a preparation method thereof, wherein the makeup removing lotion comprises a skin conditioner, a humectant, deionized water, a thickening agent, an emulsifier, a preservative and an emollient, wherein the skin conditioner comprises acetylated sodium hyaluronate, PEG-7 glyceryl cocoate, a saccharide isomer and polyquaternium-51; the makeup removing lotion disclosed by the invention has a mild makeup removing effect, does not stimulate the skin, can repair damaged epidermis, enhances the barrier function of stratum corneum, improves the dry and water-deficient state of the skin, is convenient to use, can lock the moisture of the skin, reduces the irritation, has the characteristic of flushing resistance, can supplement water deeply, and does not enable the skin to feel dry while removing the makeup.

Description

Cleansing milk with moisturizing and repairing functions and preparation method thereof
Technical Field
The invention relates to the technical field of cosmetics, in particular to a makeup removing lotion with moisturizing and repairing functions and a preparation method thereof.
Background
The makeup is to apply cosmetics and tools, and the face, five sense organs and other parts of the human body are rendered, drawn and arranged by adopting steps and skills in accordance with rules, so that the three-dimensional impression is enhanced, the shape and color are adjusted, the defects are covered, and the expression is magical, thereby achieving the purpose of beautifying. The makeup can show unique aesthetic interest of people, express personality and add charm. The successful makeup can arouse the psychological and physiological potential vitality of people, enhance the confidence, refresh the people, also help to eliminate fatigue and delay senility. The dirt on the skin is divided into two types, including sebum, water-soluble dirt which is contaminated in daily life, and oily dirt such as cosmetics. The water-soluble dirt can be easily removed only by using a common detergent; the oily dirt of cosmetics cannot be cleaned unless the oily dirt is makeup removing lotion which also takes oil as a main component. The makeup remover is used to assist in removing makeup from a female skin care product. The makeup removing cream has moderate water-oil balance, the oily components can wash away dirt, and the water-based components can keep the skin moist, so that the makeup removing cream is suitable for daily makeup and is also suitable for the skin lack of water. The basic method of selecting a makeup remover must be based on the adhesion of the previously used foundation to the skin. If the makeup is not completely removed, the residual dirt can cause pigment deposition, black spots, acne and other adverse sequelae. The first condition for making the makeup removal step is the amount of parsimony-wise makeup removal. After the existing makeup removing product is usually used, the face is tight, the water loss is serious, and the effect of moisturizing and repairing is not achieved.
Disclosure of Invention
The invention aims to overcome the problems and provide the makeup removing lotion with moisturizing and repairing effects and the preparation method thereof.
In order to achieve the purpose, the invention adopts the technical scheme that the makeup removing cream comprises a skin conditioner, a humectant, deionized water, a thickener and an emulsifier, wherein the skin conditioner comprises acetylated sodium hyaluronate, PEG-7 glyceryl cocoate, saccharide isomerate and polyquaternium-51; the skin conditioner comprises, by mass, 0.001-0.5% of acetylated sodium hyaluronate, 3-12% of PEG-7 glyceryl cocoate, 0.2-2% of saccharide isomer and-510.1-5% of polyquaternium.
The acetylated sodium hyaluronate (AcHA) is obtained by acetylating natural moisturizing factor sodium Hyaluronate (HA), and the introduction of acetyl brings lipophilicity to HA, enhances the affinity and adsorbability of HA to skin, and improves the moisturizing performance of HA. Has the following characteristics: skin substantivity: the acetyl group is lipophilic, so that AcHA can be firmly adsorbed on the surface of the skin, has small molecular weight and can quickly permeate into the horny layer, and is tightly arranged on the skin in a semi-embedded structure, so that the AcHA can reduce water loss on the surface of the skin, increase internal water accumulation, permeate into epidermis to hydrate and soften the horny layer, and simultaneously acts inside and outside, thereby playing double moisturizing effects, improving the dry and rough states of the skin and enabling the skin to be soft and elastic; moisture retention: the water binding capacity of AcHA in the stratum corneum is 2 times of that of common HA, which shows that acetyl can enable AcHA to be adsorbed on the skin for a long time and play a double moisturizing role; (iii) repairing the skin barrier: AcHA can promote epidermal cell proliferation and repair damaged epidermal cells, thereby enhancing stratum corneum barrier function and improving the natural resistance of skin.
PEG-7 glycerol cocoate: has mild makeup removing effect, no irritation to skin, and moisturizing effects.
Saccharide isomerate: saccharide isomerate (sucrose isomerate) is a colorless or yellowish transparent liquid, a natural humectant extracted from a sucrose complex, which helps water to bind keratin in the stratum corneum to achieve moisturizing effect. The saccharide isomerate is also called water-locking magnetite and is a good water-retaining agent and softening agent. The isomerized D-glucan which is prepared by biochemical technology and has the functions of repairing epidermal layer cells and improving the water replenishing capacity of skin has a composition structure similar to the human cuticle, can be combined with epsilon-amino acid functional groups when being used on the skin, is firmly combined like a magnet, and can maintain the water magnetic field capacity of the skin for a long time. The roselin kai ocean essence moisturizing series contains the components.
Polyquaternium-51: the water-retaining magnet is matched with a water-retaining magnet for use, can retain skin moisture, reduces irritation, has the characteristic of flushing resistance, and can not make the skin feel dry while removing makeup.
The inventor of the application finds that the invention combines acetylated sodium hyaluronate, PEG-7 glyceryl cocoate, saccharide isomer and polyquaternium-51 together for use, and has excellent moisturizing and repairing effects.
Preferably, the acetylated sodium hyaluronate: PEG-7 glycerol cocoate: saccharide isomerate: the mass ratio of polyquaternium-51 is 0.05:10:1: 0.5. The inventors of the present application found that the moisture retention effect is affected by the mass ratio of each component in the case of the same amount of addition, and found through a large number of experimental studies that the moisture retention effect is better in each component at the specific mass ratio.
Preferably, the makeup removing cream further comprises an emollient, and the emollient comprises caprylic/capric triglyceride, jojoba oil and sweet almond oil; the mass percentages of all components of the emollient in the makeup removing cream are 0.2-3% of caprylic/capric triglyceride, 0.2-3% of jojoba seed oil and 0.2-2% of sweet almond oil.
Jojoba oil can be tightly combined with lipids on the epidermis, and is easily applied to the cortex to provide moisturizing, repairing and skin moistening effects. The aspect of repairing the skin barrier can resist water evaporation. The most important application is to help lift the water and function of the skin to meet its physiological needs.
Sweet almond oil: the sweet almond (PRUNUS AMYGDALUS DULCIS) oil contains vitamins A, B1, B2, B6, E, protein and fatty acid, is easily absorbed by skin, has light and soft texture, is moist but not greasy, can restore the smoothness and the softness of the skin, effectively relieves the itching phenomenon of the skin, eliminates red swelling, dryness and inflammation, and also has the function of isolating ultraviolet rays. According to the application, the compounding of jojoba seed oil, sweet almond oil, acetylated sodium hyaluronate, PEG-7 glyceryl cocoate, saccharide isomerous body and polyquaternium-51 is found, and the compound has a moisturizing synergistic effect.
Preferably, the humectant comprises 1-10% of dipropylene glycol and 1-10% of butanediol by mass; the thickening agent comprises 0-0.1% of hydroxyethyl cellulose and 0.3-1% of carbomer by mass percentage.
Preferably, the emulsifier is palmitic acid/C12-16 alcohol/hydrogenated lecithin, and the mass percentage of the palmitic acid/C12-16 alcohol/hydrogenated lecithin is 0.6-1.2%. The palmitic acid/C12-16 alcohol/hydrogenated lecithin is soybean lecithin of natural origin as emulsifier, and has antiaging and moisture keeping effects.
Preferably, the mass percentage of the palmitic acid/C12-16 alcohol/hydrogenated lecithin is 0.8-1%. The inventor of the application finds that particularly when the palmitic acid/C12-16 alcohol/hydrogenated lecithin is added in the above amount, the palmitic acid/C12-16 alcohol/hydrogenated lecithin can be better matched with a skin conditioner and an emollient to realize a deep moisturizing effect.
Preferably, the makeup removing cream also comprises a preservative and a pH regulator.
Preferably, the makeup removing lotion comprises the following components in parts by weight: caprylic/capric triglyceride 3%, jojoba seed oil 1%, sweet almond oil 1%, dipropylene glycol 5%, butylene glycol 5%, acetylated sodium hyaluronate 0.05%, allantoin 0.15%, methylparaben 0.1%, hydroxyethyl cellulose 0.05%, palmitic acid/C12-16 alcohol/hydrogenated lecithin 0.8%, carbomer 0.6%, sodium hydroxide 0.24%, PEG-7 glyceryl cocoate 10%, saccharide isomer 1%, polyquaternium-510.5%, phenoxyethanol/ethylhexyl glycerin 0.8%, and balance of deionized water.
The invention also provides a preparation method of the makeup removing lotion, which comprises the following steps: 1) uniformly mixing caprylic/capric triglyceride, jojoba seed oil and sweet almond oil respectively, and heating to 70-80 ℃ for later use;
2) mixing deionized water, dipropylene glycol, butanediol, acetylated sodium hyaluronate, allantoin, methylparaben, hydroxyethyl cellulose, palmitic acid/C12-16 alcohol/hydrogenated lecithin and carbomer, heating to 70-80 ℃, homogenizing at a low speed for 3-5 minutes to uniformly disperse, and stirring at a heat preservation temperature for 10-30 minutes;
3) uniformly mixing and stirring the materials 1) and 2), homogenizing for 3-8 minutes, and stirring for 10-15 minutes in a heat preservation manner;
4) cooling to 60 deg.C, adding sodium hydroxide, cooling to 45 deg.C, sequentially adding PEG-7 glyceryl cocoate, saccharide isomerous body, polyquaternium-51 and phenoxyethanol/ethylhexyl glycerol, stirring, and discharging after inspection.
The invention has the beneficial effects that: the makeup removing lotion disclosed by the invention has a mild makeup removing effect, does not stimulate the skin, can repair damaged epidermis, enhances the barrier function of stratum corneum, improves the dry and water-deficient state of the skin, is convenient to use, can lock the moisture of the skin, reduces the irritation, has the characteristic of flushing resistance, can supplement water deeply, and does not enable the skin to feel dry while removing the makeup.
Detailed Description
To better illustrate the objects, aspects and advantages of the present invention, the present invention will be further described with reference to specific examples.
The raw materials in the following examples are all commercially available general-purpose materials unless otherwise specified.
Examples 1 to 16
Examples 1 to 16 are examples of the moisturizing and repairing cleansing cream of the present invention, the formulas of the cleansing creams of examples 1 to 6 are shown in table 1, and the formulas of examples 7 to 16 are shown in table 2:
table 1 examples 1-6 formulas of moisturizing and repairing spray type makeup remover
Figure BDA0001852783380000051
Table 2 formula of moisturizing and repairing cleansing milk of examples 7 to 16
Figure BDA0001852783380000052
Figure BDA0001852783380000061
The preparation method of the moisturizing and repairing cleansing milk comprises the following steps: 1) uniformly mixing caprylic/capric triglyceride, jojoba seed oil and sweet almond oil respectively, and heating to 70-80 ℃ for later use; 2) mixing deionized water, dipropylene glycol, butanediol, acetylated sodium hyaluronate, allantoin, methylparaben, hydroxyethyl cellulose, palmitic acid/C12-16 alcohol/hydrogenated lecithin and carbomer, heating to 70-80 ℃, homogenizing at a low speed for 3-5 minutes to uniformly disperse, and stirring at a heat preservation temperature for 10-30 minutes; 4) uniformly mixing and stirring the materials 1) and 2), homogenizing for 3-8 minutes, and stirring for 10-15 minutes in a heat preservation manner; 5) cooling to 60 deg.C, adding sodium hydroxide, cooling to 45 deg.C, sequentially adding PEG-7 glyceryl cocoate, saccharide isomerous body, polyquaternium-51 and phenoxyethanol/ethylhexyl glycerol, stirring, and discharging after inspection.
Comparative examples 1 to 4
The makeup remover formulas of comparative examples 1 to 4 are shown in table 3:
TABLE 3 cleansing milk formulations for comparative examples 1-4
Figure BDA0001852783380000071
Example 17
Evaluation of Effect of cleansing milk
The experimental method comprises the following steps: randomly selecting 200 volunteers with the age of 20-40. The makeup remover creams of examples 1 to 16 and comparative examples 1 to 4 were used for 1 month each day at night for washing 10 persons in each group. The volunteers were subjected to questionnaires and the experience of the evaluation items before and after use was compared. Grading standard: very good 5 points: good 4 points are: slightly better for 3 minutes: and 2, common score: slightly worse by 1 point: the difference 0, the evaluation results are shown in table 4:
TABLE 4 evaluation of effects of examples 1 to 16 and comparative examples 1 to 4
Group of Makeup removal effect Moisture retention Repairing effects Feeling of use
Example 1 5 5 5 5
Example 2 0 3 4 4
Example 3 2 3 5 4
Example 4 4 4 5 3
Example 5 5 5 5 2
Example 6 5 2 2 3
Example 7 5 3 3 5
Example 8 5 5 5 1
Example 9 5 2 2 5
Example 10 5 5 5 3
Example 11 5 5 5 2
Example 12 5 5 5 1
Example 13 5 1 1 5
Example 14 5 2 2 5
Example 15 5 5 5 2
Example 16 5 5 5 0
Comparative example 1 5 2 1 5
Comparative example 2 0 4 5 3
Comparative example 3 5 2 3 5
Comparative example 4 5 2 2 5
As can be seen from Table 4, the cleansing milk of the present invention has good moisturizing repair effect, wherein the effect of example 1 is the best, the cleansing milk has excellent cleansing and moisturizing repair effects, and the use feeling is also the best, and the change in the content of PEG-7 glyceryl cocoate is examined on the effect of the cleansing milk of the present invention in examples 1 to 5, from which it can be seen that, when the content of PEG-7 glyceryl cocoate is 3%, the cleansing effect is not provided, and the moisturizing effect is reduced compared with example 1, indicating that the content of PEG-7 glyceryl cocoate not only affects the moisturizing effect, but also affects the cleansing effect, and when the content exceeds 10%, the use feeling is poor, and the content change in the content of saccharide isomerate is examined on the effect of the cleansing milk of the present invention in examples 6 to 8, and when the content of saccharide isomerate is less than 1%, the moisturizing and repairing effect of the polysaccharide is obviously lower than that of example 1, which shows that the saccharide isomer plays an important role in moisturizing and repairing, and similarly, when the content of the saccharide isomer is 2%, the use feeling is poor; examples 9-12 investigate the influence of the content change of the polyquaternium-51 on the effect of the makeup removing cream, when the content of the polyquaternium-51 is lower than 1%, the moisturizing and repairing effect is obviously lower than that of example 1, and the using feeling of the polyquaternium-51 is gradually reduced along with the increase of the content; examples 13 to 16 examined the effect of the content change of the sodium hyaluronate on the cleansing milk of the present invention, and the moisturizing and repairing effect was increased with the increase of the content, and the effect was optimized when the content was 0.05%. The PEG-7 glyceryl cocoate, the saccharide isomer, the polyquaternium-51 and the acetylated sodium hyaluronate are respectively lacked in the comparative examples 1 to 4, so that the moisturizing effect of the four components can be reduced due to the fact that any one of the four components is lacked, and the moisturizing effect is better than that of one, two or three components when the four components are used simultaneously.
Example 18
This example demonstrates the effect of mass ratios of sodium acetylated hyaluronate, PEG-7 glyceryl cocoate, saccharide isomerate, polyquaternium-51 on the moisture retention performance of the present invention.
According to the formula of the example 1, only the contents of the acetylated sodium hyaluronate, the PEG-7 glyceryl cocoate, the saccharide isomer and the polyquaternium-51 are changed, and the acetylated sodium hyaluronate, the PEG-7 glyceryl cocoate, the saccharide isomer and the polyquaternium-51 are respectively added into the formula of the example 1 according to the mixture ratio in the table 5, so that the moisturizing effect is verified, and the test result is shown in the table 6.
The test method is as follows:
1. test of moisturizing Effect
Test samples: examples samples
The tested person: 90 women of 20-24 years old
Testing an instrument: a Corneometer CM 825 used for detecting moisture content of stratum corneum
Test area: medial left forearm and medial right forearm
The test method comprises the following steps: the test samples were applied in a single application (2.0. + -. 0.1) mg/cm2 using a latex finger cuff to apply the test sample to a 3cm by 3cm test area.
And (3) testing period: 0h, 2h, 4h and 6h
Scheme design: 0 h: no product is used 2-3 days before the tested part, and water can not be contacted for 1-3 h. Before the test, the inner side of the forearm is cleaned uniformly and wiped clean. Prior to testing, subjects sit still in a laboratory at a temperature of 21. + -. 1 ℃ and a relative humidity of 50. + -. 10% for 20min, without drinking water or drink, with the forearms exposed. After the test is started, the parameter measurement of the moisture content of the stratum corneum of the skin is carried out on the sample smearing area.
2 h: and (3) carrying out parameter measurement on the moisture content of the stratum corneum of the skin on the sample smearing area.
4 h: and (3) carrying out parameter measurement on the moisture content of the stratum corneum of the skin on the sample smearing area.
6 h: and (3) carrying out parameter measurement on the moisture content of the stratum corneum of the skin on the sample smearing area.
In each group, 10 subjects were randomly selected for testing, the moisture content of the inner horny layer of the left and right forearms was measured, and the average of the moisture content of the inner left arm and the average of the moisture content of the inner right arm and the increase thereof were obtained from the data of 10 subjects, and the results are shown in table 6.
TABLE 5
Figure BDA0001852783380000101
Figure BDA0001852783380000111
TABLE 6 average moisture content and increase in the medial horny layer of the left and right forearms (group A1-group I1)
Test time/h 0 2 4 6
Group A1 mean/MMV 33.89 54.31 55.56 55.32
Group B1 mean/MMV 32.67 51.66 52.73 52.52
Group C1 mean/MMV 33.84 53.89 55.19 54.98
D1 group mean/MMV 34.08 52.75 54.05 53.76
Group average/MMV E1 34.27 54.3 55.63 55.31
Group F1 mean/MMV 33.52 52.31 53.15 52.86
Group G1 mean/MMV 33.25 51.94 52.99 52.6
H1 group mean/MMV 33.24 52.11 53.07 52.87
Group I1 mean/MMV 33.87 52.81 54.21 53.84
Moisture content increase/MMV of group A1 0 20.42 21.67 21.43
Moisture content increase/MMV of group B1 0 18.99 20.06 19.85
Moisture content increase/MMV of group C1 0 20.05 21.35 21.14
D1 group moisture content increase/MMV 0 18.67 19.97 19.68
E1 group moisture content increase/MMV 0 20.03 21.36 21.04
Moisture content increase/MMV of group F1 0 18.79 19.63 19.34
Moisture content increase/MMV of group G1 0 18.69 19.74 19.35
H1 group moisture content increase/MMV 0 18.87 19.85 19.63
H1 group moisture content increase/MMV 0 18.94 20.34 19.97
As can be seen from tables 5 and 6, when the amounts of acetylated sodium hyaluronate, PEG-7 glyceryl cocoate, saccharide isomerate, and polyquaternium-51 added were the same, the moisturizing effects differed, and as a result, it was found that the moisturizing effect was the best when the mass ratio of acetylated sodium hyaluronate, PEG-7 glyceryl cocoate, saccharide isomerate, and polyquaternium-51 was 0.05:10:1: 0.5.
Example 19
This example demonstrates the effect of the amount of palmitic acid (and) C12-16 alcohol (and) hydrogenated lecithin added on the moisturizing properties of the present invention.
The moisturizing effect was verified by adding only palmitic acid (and) C12-16 alcohol (and) hydrogenated lecithin to the formulation of example 1 according to the formulation of example 1 and the ratio in Table 7, and the test results are shown in Table 8. The test method was the same as in example 18.
TABLE 7
Figure BDA0001852783380000121
TABLE 8 average and incremental water content of the stratum corneum of the inner forearm (A2-G2)
Test time/h 0 2 4 6
Group A2 mean/MMV 33.62 53 54.12 53.94
Group B2 mean/MMV 34.59 51.82 52.96 52.74
Group C2 mean/MMV 35.10 53.78 54.79 54.4
D2 group mean/MMV 34.51 54.2 55.26 54.91
Group average/MMV E2 34.25 53.96 54.82 54.6
Group F2 mean/MMV 34.08 53.76 54.67 54.43
Group G2 mean/MMV 35.09 54.78 55.67 55.42
Moisture content increase/MMV of group A2 0 19.38 20.50 20.32
Moisture content increase/MMV of group B2 0 18.20 19.34 19.12
Moisture content increase/MMV of group C2 0 18.68 19.69 19.30
D2 group moisture content increase/MMV 0 19.69 20.75 20.40
E2 group moisture content increase/MMV 0 19.71 20.57 20.35
Moisture content increase/MMV of group F2 0 19.68 20.59 20.35
Moisture content increase/MMV of group G2 0 19.69 20.58 20.33
As can be seen from table 7, the moisturizing effect is better with the increase of the content of palmitic acid (and) C12-16 alcohol (and) hydrogenated lecithin, which indicates that palmitic acid (and) C12-16 alcohol (and) hydrogenated lecithin can exert the moisturizing effect in the formulation of the present invention, and the moisturizing effect is better and significantly increased when the addition amount of palmitic acid (and) C12-16 alcohol (and) hydrogenated lecithin is greater than 0.8%, but the moisturizing effect is not significantly increased when the addition amount of palmitic acid (and) C12-16 alcohol (and) hydrogenated lecithin is greater than 1%, and therefore the addition amount of palmitic acid (and) C12-16 alcohol (and) hydrogenated lecithin is more preferably 0.8-1%.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like made within the spirit and principle of the present invention should be included in the scope of the present invention.

Claims (8)

1. The makeup removing lotion is characterized by comprising a skin conditioner, a humectant, deionized water, a thickener and an emulsifier, wherein the skin conditioner comprises acetylated sodium hyaluronate, PEG-7 glyceryl cocoate, saccharide isomerous body and polyquaternium-51; the skin conditioner comprises the following components, by mass, 0.001-0.5% of acetylated sodium hyaluronate, 3-12% of PEG-7 glyceryl cocoate, 0.2-2% of saccharide isomer and-510.1-5% of polyquaternium; the acetylated sodium hyaluronate: PEG-7 glycerol cocoate: saccharide isomerate: the mass ratio of the polyquaternium-51 is 0.05:10:1: 0.5.
2. The cleansing milk of claim 1 further comprising an emollient comprising caprylic/capric triglyceride, jojoba oil, sweet almond oil; the mass percentages of all components of the emollient in the makeup removing cream are 0.2-3% of caprylic/capric triglyceride, 0.2-3% of jojoba seed oil and 0.2-2% of sweet almond oil.
3. The makeup removing cream according to claim 1, characterized in that the humectant comprises 1-10% of dipropylene glycol and 1-10% of butanediol by mass; the thickening agent comprises 0-0.1% of hydroxyethyl cellulose and 0.3-1% of carbomer by mass percentage.
4. The cleansing milk according to claim 1, wherein the emulsifier is palmitic acid/C12-16 alcohol/hydrogenated lecithin, and the mass percentage of the palmitic acid/C12-16 alcohol/hydrogenated lecithin is 0.6-1.2%.
5. The cleansing milk according to claim 4, wherein the mass percentage of palmitic acid/C12-16 alcohol/hydrogenated lecithin is 0.8-1%.
6. The cleansing milk according to claim 1, further comprising a preservative, a pH adjuster.
7. The makeup removing cream according to claim 1, characterized by comprising the following components in parts by weight: caprylic/capric triglyceride 3%, jojoba seed oil 1%, sweet almond oil 1%, dipropylene glycol 5%, butylene glycol 5%, acetylated sodium hyaluronate 0.05%, allantoin 0.15%, methylparaben 0.1%, hydroxyethyl cellulose 0.05%, palmitic acid/C12-16 alcohol/hydrogenated lecithin 0.8%, carbomer 0.6%, sodium hydroxide 0.24%, PEG-7 glyceryl cocoate 10%, saccharide isomer 1%, polyquaternium-510.5%, phenoxyethanol/ethylhexyl glycerin 0.8%, and balance of deionized water.
8. A method for preparing the cleansing milk of claim 7, comprising the steps of: 1) uniformly mixing caprylic/capric triglyceride, jojoba seed oil and sweet almond oil respectively, and heating to 70-80 ℃ for later use;
2) mixing deionized water, dipropylene glycol, butanediol, acetylated sodium hyaluronate, allantoin, methylparaben, hydroxyethyl cellulose, palmitic acid/C12-16 alcohol/hydrogenated lecithin and carbomer, heating to 70-80 ℃, homogenizing at a low speed for 3-5 minutes to uniformly disperse, and stirring at a heat preservation temperature for 10-30 minutes;
3) uniformly mixing and stirring the materials 1) and 2), homogenizing for 3-8 minutes, and stirring for 10-15 minutes in a heat preservation manner;
4) cooling to 60 deg.C, adding sodium hydroxide, cooling to 45 deg.C, sequentially adding PEG-7 glyceryl cocoate, saccharide isomerous body, polyquaternium-51 and phenoxyethanol/ethylhexyl glycerol, stirring, and discharging after inspection.
CN201811305283.5A 2018-11-02 2018-11-02 Cleansing milk with moisturizing and repairing functions and preparation method thereof Active CN109106622B (en)

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