CN107921031A - 给予谷氨酰胺酶抑制剂的方法 - Google Patents

给予谷氨酰胺酶抑制剂的方法 Download PDF

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Publication number
CN107921031A
CN107921031A CN201680031557.9A CN201680031557A CN107921031A CN 107921031 A CN107921031 A CN 107921031A CN 201680031557 A CN201680031557 A CN 201680031557A CN 107921031 A CN107921031 A CN 107921031A
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alkyl
substituted
compound
aryl
heteroaryl
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Chinese (zh)
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M.I.格罗斯
M.K.班尼特
C.莫利诺瓦
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Calithera Biosciences Inc
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Calithera Biosciences Inc
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/433—Thidiazoles
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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CN201680031557.9A 2015-03-30 2016-03-30 给予谷氨酰胺酶抑制剂的方法 Pending CN107921031A (zh)

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US201562139928P 2015-03-30 2015-03-30
US62/139928 2015-03-30
US201562168112P 2015-05-29 2015-05-29
US62/168112 2015-05-29
PCT/US2016/024998 WO2016160980A1 (en) 2015-03-30 2016-03-30 Methods of administering glutaminase inhibitors

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EP (1) EP3277276B1 (enExample)
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KR (1) KR20170131650A (enExample)
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021169984A1 (zh) * 2020-02-24 2021-09-02 甫康（上海）健康科技有限责任公司 聚adp核糖聚合酶抑制剂在抗冠状病毒中的应用
WO2022001784A1 (zh) * 2020-06-30 2022-01-06 广东省中医院 谷氨酰胺酶抑制剂在制备治疗银屑病的药物中的应用
WO2023024664A1 (zh) * 2021-08-26 2023-03-02 山东第一医科大学附属眼科研究所(山东省眼科研究所、山东第一医科大学附属青岛眼科医院) Abt-263在制备抑制角膜移植免疫排斥反应的药物中的应用

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8604016B2 (en) 2011-11-21 2013-12-10 Calithera Biosciences Inc. Heterocyclic inhibitors of glutaminase
JP6275153B2 (ja) 2012-11-16 2018-02-07 キャリセラ バイオサイエンシーズ， インコーポレイテッド ヘテロ環式グルタミナーゼ阻害剤
MX2016014143A (es) 2014-04-30 2017-02-15 Pfizer Derivados de diheterociclo enlazado a cicloalquilo.
EA037738B1 (ru) 2014-08-07 2021-05-17 Калитера Байосайенсиз, Инк. Кристаллические формы ингибиторов глутаминазы
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