CN107874060A - 一种降血糖的保健食品及其制备方法 - Google Patents
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Abstract
本发明提供一种降血糖的保健食品，它由如下重量份数的原料制备得到：决明子20‑30份、金银花15‑25份、黄芥子10‑15份、青果10‑25份、平卧菊三七10‑20份、薄荷10‑15份、淡竹叶5‑10份，并采用了相应的制备方法，本发明具有降血糖功效。
Description
技术领域
本发明属于中医药保健技术领域，具体涉及一种降血糖的保健食品。
背景技术
糖尿病是一组以高血糖为特征的代谢性疾病。高血糖则是由于胰岛素分泌缺陷或其生物作用受损，或两者兼有引起。糖尿病时长期存在的高血糖，导致各种组织，特别是眼、肾、心脏、血管、神经的慢性损害、功能障碍。目前缺少降血糖的保健食品。
发明内容
发明目的：本发明提供了一种降血糖的保健食品。
技术方案：一种降血糖的保健食品，它由如下重量份数的原料制备得到：决明子20-30份、金银花15-25份、黄芥子10-15份、青果10-25份、平卧菊三七10-20份、薄荷10-15份、淡竹叶5-10份。
所述降血糖的保健食品，它由如下重量份数的原料制备得到：决明子28份、金银花17份、黄芥子13份、青果17份、平卧菊三七15份、薄荷12份、淡竹叶7份。
所述所述降血糖的保健食品，保健食品剂型为固体饮料。
所述降血糖的保健食品，制备方法为：取上述原料，粉碎成细粉，分装，即得固体饮料。
有益效果：本发明具有降血糖作用。
具体实施方式
以下通过实施例形式对本发明的上述内容再作进一步的详细说明，但不应将此理解为本发明上述主题的范围仅限于以下的实施例，凡基于本发明上述内容所实现的技术均属于本发明的范围。
实施例1：取决明子20份、金银花25份、黄芥子10份、青果25份、平卧菊三七10份、薄荷15份、淡竹叶5份，制备方法为：取上述原料，粉碎成细粉，分装，即得固体饮料。
实施例2：取决明子30份、金银花15份、黄芥子15份、青果10份、平卧菊三七20份、薄荷10份、淡竹叶10份，制备方法为：取上述原料，粉碎成细粉，分装，即得固体饮料。
实施例3：取决明子28份、金银花17份、黄芥子13份、青果17份、平卧菊三七15份、薄荷12份、淡竹叶7份，制备方法为：取上述原料，粉碎成细粉，分装，即得固体饮料。
实施例4：本发明降血糖作用实验研究
样品的制备：按上述实施例3方法制备，制备成固体饮料。
给药剂量：则按大鼠体重计，低剂量、中剂量和高剂量分别为5g生药量/kg、10g生药量/kg和20g生药量/kg。
主要仪器和试剂：链脉佐菌素(STZ)，Sigma公司。微量快速血糖仪OneTouch-ll型,美国强生公司。血糖试纸，美国强生公司。尿糖试纸，广州市珠江生化试剂公司。MPZOOB电子天平，上海天普分析仪器有限公司。格列奇特片，石家庄四药厂，批号：20130305，规格80mg*60s。
实验动物：SD大鼠180-220g，雄性，由上海斯莱克实验动物有限责任公司提供，生产许可证：SCXK(沪)2007-0005。
动物饲养：自由饮食饲养5d后进行实验，恒温23℃，湿度60％，人工照明12小时白天与12小时黑夜交替，给予常规的实验室饮食，不限制饮水。
实验过程：动物模型的制备：将实验用大鼠用天平称量体重，STZ按60mg/kg体重称取后，溶解于pH值4.5，浓度为0.1mol/L的柠檬酸-柠檬酸钠缓冲液，配制成2％的溶液，过滤器除菌，将禁食12h的大鼠腹腔注射，观察2h，开始饮食。3d后取尾静脉尖血用OneTouchll型血糖仪检测血糖，并同时测尿糖。以尿糖(+++)以上，血糖16.5mmol/L以上，出现多尿、多饮、多食症状的大鼠即为造模成功的糖尿病大鼠。实验期间大鼠正常饮食水。未成模的大鼠于7d后再次腹腔注射STZ。分组及给药：取糖尿病大鼠，随机分为5组，每组10只，即糖尿病模型组、本发明高中低剂量组、格列齐特对照组。按上述剂量分别灌胃。各组大鼠分别在20d后空腹静脉取血，测定血糖的浓度。
实验结果：
可发现本发明高中低剂量组和格列齐特对照组一样可显著降低实验性糖尿病鼠体内血糖的浓度。
表1各组模型实验后各项生化指标的变化(χ±s，n＝10)
注:同模型组相比*p<0.05**<0.01
结论：本发明各剂量组能降低实验性高糖大鼠血糖水平。
显然，本发明的上述实施例仅仅是为清楚地说明本发明所作的举例，而并非是对本发明的实施方式的限定。对于所属领域的普通技术人员来说，在上述说明的基础上还可以做出其它不同形式的变化或变动。这里无需也无法对所有的实施方式予以穷举。而这些属于本发明的实质精神所引伸出的显而易见的变化或变动仍属于本发明的保护范围。
Claims (4)
1.一种降血糖的保健食品，其特征在于，它由如下重量份数的原料制备得到：决明子20-30份、金银花15-25份、黄芥子10-15份、青果10-25份、平卧菊三七10-20份、薄荷10-15份、淡竹叶5-10份。
2.如权利要求1所述降血糖的保健食品，其特征在于，它由如下重量份数的原料制备得到：决明子28份、金银花17份、黄芥子13份、青果17份、平卧菊三七15份、薄荷12份、淡竹叶7份。
3.如权利要求1所述降血糖的保健食品，其特征在于，保健食品剂型为固体饮料。
4.如权利要求1所述降血糖的保健食品，其特征在于，制备方法为：取上述原料，粉碎成细粉，分装，即得固体饮料。
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108514064A (zh) * | 2018-05-10 | 2018-09-11 | 南昌大学 | 一种平卧菊三七固体饮料的生产方法 |
| CN111109587A (zh) * | 2018-11-01 | 2020-05-08 | 韩连慧 | 具有降低人体内血糖水平、增强免疫力的食品及制备方法 |
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| CN104366636A (zh) * | 2014-10-30 | 2015-02-25 | 袁丁 | 一种平卧菊三七复合制剂及制备方法及应用 |
| CN106924317A (zh) * | 2015-12-30 | 2017-07-07 | 北京万源普达医疗科技有限公司 | 一种平卧菊三七提取物的制备方法及降血糖的中药制剂 |
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| CN104171188A (zh) * | 2014-08-04 | 2014-12-03 | 廖为明 | 平卧菊三七养生茶 |
| CN104366636A (zh) * | 2014-10-30 | 2015-02-25 | 袁丁 | 一种平卧菊三七复合制剂及制备方法及应用 |
| CN106924317A (zh) * | 2015-12-30 | 2017-07-07 | 北京万源普达医疗科技有限公司 | 一种平卧菊三七提取物的制备方法及降血糖的中药制剂 |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108514064A (zh) * | 2018-05-10 | 2018-09-11 | 南昌大学 | 一种平卧菊三七固体饮料的生产方法 |
| CN111109587A (zh) * | 2018-11-01 | 2020-05-08 | 韩连慧 | 具有降低人体内血糖水平、增强免疫力的食品及制备方法 |
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